238 Publikationen
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2024 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2990611Unraveling the interaction of co-encapsulated Saccharomyces cerevisiae and Metarhizium brunneum in calcium alginate-based attract-and-kill beadsPUB | DOI | WoS | PubMed | Europe PMC
Hermann KM, Grünberger A, Patel A (2024)
Pest Management Science. -
2024 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2990164
Protocol for microfluidic single-cell cultivation and live-cell imaging of Chinese hamster ovary suspension cell linesPUB | PDF | DOI | WoS | PubMed | Europe PMC
Schmitz J, Yermakov B, Grünberger A (2024)
STAR Protocols 5(2): 103106. -
2024 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2991980High-throughput detection of potential bacteriocin producers in a large strain library using live fluorescent biosensorsPUB | DOI | WoS | PubMed | Europe PMC
Otto SJ, Teichmann L, Fante N, Crauwels P, Grünberger A, Neddermann T, Riedel CU (2024)
Frontiers in Bioengineering and Biotechnology 12: 1405202. -
2024 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2990547
Time-resolved cell-to-cell heterogeneity of Listeria innocua after nisin exposurePUB | PDF | DOI | WoS | PubMed | Europe PMC
Fante N, Desiderato CK, Riedel CU, Grünberger A (2024)
Frontiers in Bioengineering and Biotechnology 12: 14 Seiten. -
2024 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2986983Quantifying microbial robustness in dynamic environments using microfluidic single-cell cultivationPUB | DOI | WoS | PubMed | Europe PMC
Blöbaum L, Torello Pianale L, Olsson L, Grünberger A (2024)
Microbial Cell Factories 23(1): 44. -
2023 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2968932
Experimental ks estimation: A comparison of methods for Corynebacterium glutamicum from lab to microfluidic scale.PUB | PDF | DOI | WoS | PubMed | Europe PMC
Steinhoff H, Finger M, Osthege M, Golze C, Schito S, Noack S, Buchs J, Grünberger A (2023)
Biotechnology and Bioengineering 120(5): 1167-1449. -
2023 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2988959Machine learning in bioprocess development: from promise to practicePUB | DOI | WoS | PubMed | Europe PMC
Helleckes LM, Hemmerich J, Wiechert W, von Lieres E, Grünberger A (2023)
Trends in Biotechnology 41(6): 817-835. -
2023 | Preprint | Veröffentlicht | PUB-ID: 2985556Coupling Cell Size Regulation and Proliferation Dynamics of Reveals Cell Division Based on Surface AreaPUB | DOI | PubMed | Europe PMC
Nieto C, Täuber S, Blöbaum L, Vahdat Z, Grünberger A, Singh A (2023)
bioRxiv. -
2023 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2982187Protocol to perform dynamic microfluidic single-cell cultivation of C.glutamicumPUB | DOI | WoS | PubMed | Europe PMC
Blöbaum L, Täuber S, Grünberger A (2023)
STAR Protocols 4(3): 102436. -
2023 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2969695Microfluidic single-cell scale-down systems: introduction, application, and future challengesPUB | DOI | WoS | PubMed | Europe PMC
Täuber S, Grünberger A (2023)
Current Opinion in Biotechnology 81: 102915. -
2022 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2962620
Genetically Encoded Ratiometric pH Sensors for the Measurement of Intra- and Extracellular pH and Internalization RatesPUB | PDF | DOI | WoS | PubMed | Europe PMC
Karsten L, Gött-Zink L, Schmitz J, Hoffrogge R, Grünberger A, Kottke T, Müller K (2022)
Biosensors 12(5): 271. -
2022 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2964098
Microfluidic single-cell scale-down bioreactors: A proof-of-concept for the growth of Corynebacterium glutamicum at oscillating pH valuesPUB | PDF | DOI | WoS | PubMed | Europe PMC | Preprint
Täuber S, Blöbaum L, Steier V, Oldiges M, Grünberger A (2022)
Biotechnology and Bioengineering 119(11): 3194-3209. -
2022 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2963033
Assessing the growth kinetics and stoichiometry of Escherichia coli at the single-cell levelPUB | PDF | DOI | Download (ext.) | WoS | PubMed | Europe PMC
Smaluch K, Wollenhaupt B, Steinhoff H, Kolhheyer D, Grünberger A, Dusny C (2022)
Engineering in Life Sciences . -
2022 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2967671Microbial lifelines in bioprocesses: From concept to applicationPUB | DOI | WoS | PubMed | Europe PMC
Blöbaum L, Haringa C, Grünberger A (2022)
Biotechnology Advances 62. -
2022 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2963556
Single-Cell Analysis of CHO Cells Reveals Clonal Heterogeneity in Hyperosmolality-Induced Stress ResponsePUB | PDF | DOI | Download (ext.) | WoS | PubMed | Europe PMC
Romanova N, Schmitz J, Strakeljahn M, Grünberger A, Bahnemann J, Noll T (2022)
Cells 11(11): 1763. -
2022 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2964097Microfluidic Reproduction of Dynamic Bioreactor Environment Based on Computational LifelinesPUB | DOI
Ho P, Täuber S, Stute B, Grünberger A, von Lieres E (2022)
Frontiers in Chemical Engineering 4: 826485. -
2022 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2962029Microfluidics in Biotechnology: Overview and Status QuoPUB | DOI | PubMed | Europe PMC
Bahnemann J, Grünberger A (2022)
Advances in Biochemical Engineering, Biotechnology : 1-16. -
2021 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2956409
Human Blood Serum Induces p38-MAPK- and Hsp27-Dependent Migration Dynamics of Adult Human Cardiac Stem Cells: Single-Cell Analysis via a Microfluidic-Based Cultivation PlatformPUB | PDF | DOI | WoS | PubMed | Europe PMC
Schmitz J, Höving AL, Schmidt KE, Greiner J, Knabbe C, Kaltschmidt B, Grünberger A, Kaltschmidt C (2021)
Biology 10(8): 708. -
2021 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2949089
Development and application of a cultivation platform for mammalian suspension cell lines with single-cell resolutionPUB | Dateien verfügbar | DOI | WoS | PubMed | Europe PMC | Preprint
Schmitz J, Täuber S, Westerwalbesloh C, von Lieres E, Noll T, Grünberger A (2021)
Biotechnology and Bioengineering 118(2): 992-1005. -
2021 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2956806
Formalin-casein enhances water absorbency of calcium alginate beads and activity of encapsulated Metarhizium brunneum and Saccharomyces cerevisiaePUB | PDF | DOI | WoS | PubMed | Europe PMC
Hermann KM, Grünberger A, Patel A (2021)
World Journal of Microbiology and Biotechnology 37(9): 156. -
2021 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2967242Desiccation-tolerant fungal blastospores: From production to applicationPUB | DOI | WoS
Dietsch R, Jakobs-Schoenwandt D, Grünberger A, Patel A (2021)
Current Research in Biotechnology 3: 323-339. -
2021 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2957323
Growth response and recovery of Corynebacterium glutamicum colonies on single-cell level upon defined pH stress pulsesPUB | PDF | DOI | WoS | PubMed | Europe PMC | Preprint
Täuber S, Blöbaum L, Wendisch VF, Grünberger A (2021)
Frontiers in Microbiology 12: 711893. -
2021 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2959820
How to Perform a Microfluidic Cultivation Experiment—A Guideline to SuccessPUB | PDF | DOI | WoS | PubMed | Europe PMC
Täuber S, Schmitz J, Blöbaum L, Fante N, Steinhoff H, Grünberger A (2021)
Biosensors 11(12): 485. -
2021 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2955090
Growth and eGFP-production of CHO-K1 suspension cells cultivated from single-cell to laboratory scalePUB | PDF | DOI | WoS | PubMed | Europe PMC | Preprint
Schmitz J, Hertel O, Yermakov B, Noll T, Grünberger A (2021)
Frontiers in Bioengineering and Biotechnology 9: 716343. -
2021 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2964708
Ein Wechselbad für Mikroben: Wachsen unter dynamischen UmweltbedingungenPUB | PDF | DOI
Blöbaum L, Täuber S, Grünberger A (2021)
BIOspektrum 27(5): 491-493. -
2021 | Zeitschriftenaufsatz | Im Druck | PUB-ID: 2957505Exploiting unconventional prokaryotic hosts for industrial biotechnologyPUB | DOI | WoS | PubMed | Europe PMC
Blombach B, Grünberger A, Centler F, Wierckx N, Schmid J (In Press)
Trends in biotechnology. -
2021 | Zeitschriftenaufsatz | Angenommen | PUB-ID: 2955245Towards an automatic analysis of CHO-K1 suspension growth in microfluidic single-cell cultivationPUB | DOI | WoS | PubMed | Europe PMC
Stallmann D, Göpfert JP, Schmitz J, Grünberger A, Hammer B (Accepted)
Bioinformatics . -
2021 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2951549Measurement Techniques to Resolve and Control Population Dynamics of Mixed-Culture Processes.PUB | DOI | WoS | PubMed | Europe PMC
Schlembach I, Grünberger A, Rosenbaum MA, Regestein L (2021)
Trends in Biotechnology. -
2021 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2957513The iSplit GFP assay detects intracellular recombinant proteins in Bacillus subtilisPUB | DOI | WoS | PubMed | Europe PMC
Lenz P, Hilgers F, Burmeister A, Zimmermann L, Volkenborn K, Grünberger A, Kohlheyer D, Drepper T, Jaeger K-E, Knapp A (2021)
Microbial cell factories 20(1): 174. -
2021 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2955524(Optochemical) Control of Synthetic Microbial Coculture Interactions on a Microcolony LevelPUB | DOI | WoS | PubMed | Europe PMC
Burmeister A, Akhtar Q, Hollmann L, Tenhaef N, Hilgers F, Hogenkamp F, Sokolowsky S, Marienhagen J, Noack S, Kohlheyer D, Grünberger A (2021)
ACS synthetic biology. -
2021 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2955913Reducing phenotypic instabilities of a microbial population during continuous cultivation based on cell switching dynamicsPUB | DOI | WoS | PubMed | Europe PMC
Nguyen TM, Telek S, Zicler A, Martinez JA, Zacchetti B, Kopp J, Slouka C, Herwig C, Grünberger A, Delvigne F (2021)
Biotechnology and bioengineering. -
2021 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2951151Microfluidics in Biotechnology: Quo VadisPUB | DOI | PubMed | Europe PMC
Winkler S, Grünberger A, Bahnemann J (2021)
Advances in biochemical engineering/biotechnology: 1-26. -
2020 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2946333
Engineering and application of a biosensor with focused ligand specificityPUB | PDF | DOI | WoS | PubMed | Europe PMC
Della Corte D, van Beek HL, Syberg F, Schallmey M, Tobola F, Cormann KU, Schlicker C, Baumann PT, Krumbach K, Sokolowsky S, Morris CJ, et al. (2020)
Nature communications 11(1): 4851. -
2020 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2948721
Microfluidics for Biotechnology: Bridging Gaps to Foster Microfluidic ApplicationsPUB | PDF | DOI | WoS | PubMed | Europe PMC
Ortseifen V, Viefhues M, Wobbe L, Grünberger A (2020)
Frontiers in Bioengineering and Biotechnology 8: 589074. -
2020 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2948408dMSCC: a microfluidic platform for microbial single-cell cultivation of Corynebacterium glutamicum under dynamic environmental medium conditionsPUB | DOI | WoS | PubMed | Europe PMC
Täuber S, Golze C, Ho P, von Lieres E, Grünberger A (2020)
Lab on a chip. -
2020 | Preprint | Veröffentlicht | PUB-ID: 2944674dMSCC: A microfluidic platform for microbial single-cell cultivation under dynamic environmental medium conditionsPUB | DOI | Preprint
Täuber S, Golze C, Ho P, von Lieres E, Grünberger A (2020)
bioRxiv. -
2020 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2944673
Visualisierung von Mutationen auf EinzelzellebenePUB | PDF | DOI
Täuber S, Dormeyer M, Commichau FM, Grünberger A (2020)
BIOspektrum 26(4): 388-390. -
2020 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2941821
Dynamic Environmental Control in Microfluidic Single‐Cell Cultivations: From Concepts to ApplicationsPUB | PDF | DOI | Download (ext.) | WoS | PubMed | Europe PMC
Täuber S, Lieres E, Grünberger A (2020)
Small 16(16): 1906670. -
2020 | Zeitschriftenaufsatz | Im Druck | PUB-ID: 2939030Microfluidic cultivation and analysis tools for interaction studies of microbial co-cultures.PUB | DOI | WoS | PubMed | Europe PMC
Burmeister A, Grünberger A (In Press)
Current opinion in biotechnology 62: 106-115. -
2019 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2937575
Genetically Encoded Photosensitizers as Light-Triggered Antimicrobial Agents.PUB | PDF | DOI | Download (ext.) | WoS | PubMed | Europe PMC
Hilgers F, Bitzenhofer NL, Ackermann Y, Burmeister A, Grünberger A, Jaeger K-E, Drepper T (2019)
International journal of molecular sciences 20(18): 4608. -
2019 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2936034Microbial single-cell growth response at defined carbon limiting conditionsPUB | DOI | WoS | PubMed | Europe PMC
Lindemann D, Westerwalbesloh C, Kohlheyer D, Grünberger A, von Lieres E (2019)
RSC ADVANCES 9(25): 14040-14050. -
2019 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2935887Segregostat: a novel concept to control phenotypic diversification dynamics on the example of Gram-negative bacteria.PUB | DOI | WoS | PubMed | Europe PMC
Sassi H, Nguyen TM, Telek S, Gosset G, Grünberger A, Delvigne F (2019)
Microbial biotechnology 12(5): 1064-1075. -
2019 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2935495Reproduction of Large-Scale Bioreactor Conditions on Microfluidic Chips.PUB | DOI | WoS | PubMed | Europe PMC
Ho P, Westerwalbesloh C, Kaganovitch E, Grünberger A, Neubauer P, Kohlheyer D, Lieres E von (2019)
Microorganisms 7(4): 105. -
2019 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2937237mycelyso - high-throughput analysis of Streptomyces mycelium live cell imaging dataPUB | DOI | WoS | PubMed | Europe PMC
Sachs CC, Koepff J, Wiechert W, Grünberger A, Noh K (2019)
BMC bioinformatics 20(1): 452. -
2019 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2934065Tailoring the properties of (catalytically)-active inclusion bodies.PUB | DOI | WoS | PubMed | Europe PMC
Jager VD, Kloss R, Grünberger A, Seide S, Hahn D, Karmainski T, Piqueray M, Embruch J, Longerich S, Mackfeld U, Jaeger K-E, et al. (2019)
Microbial cell factories 18(1): 33. -
2019 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2939585Microfluidic single-cell analysis in biotechnology: from monitoring towards understanding.PUB | DOI | WoS | PubMed | Europe PMC
Dusny C, Grünberger A (2019)
Current opinion in biotechnology 63: 26-33. -
2019 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2937529 PUB
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2019 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2935496A microfluidic photobioreactor for simultaneous observation and cultivation of single microalgal cells or cell aggregates.PUB | DOI | WoS | PubMed | Europe PMC
Westerwalbesloh C, Brehl C, Weber S, Probst C, Widzgowski J, Grünberger A, Pfaff C, Nedbal L, Kohlheyer D (2019)
PloS one 14(4): e0216093. -
2019 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2933358Heterogeneity Studies of Mammalian Cells for Bioproduction. From Tools to ApplicationPUB | DOI | WoS | PubMed | Europe PMC
Schmitz J, Noll T, Grünberger A (2019)
Trends in Biotechnology 37(6): 645-660. -
2019 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2935584When a single lineage is not enough: Uncertainty-Aware Tracking for spatio-temporal live-cell image analysisPUB | DOI | WoS | PubMed | Europe PMC
Theorell A, Seiffarth J, Grünberger A, Noeh K (2019)
BIOINFORMATICS 35(7): 1221-1228. -
2019 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2932955A microfluidic co-cultivation platform to investigate microbial interactions at defined microenvironmentsPUB | DOI | WoS | PubMed | Europe PMC
Burmeister A, Hilgers F, Langner A, Westerwalbesloh C, Kerkhoff Y, Tenhaef N, Drepper T, Kohlheyer D, von Lieres E, Noack S, Grünberger A (2019)
LAB ON A CHIP 19(1): 98-110. -
2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2920273Catalytically active inclusion bodies of L-lysine decarboxylase from E. coli for 1,5-diaminopentane productionPUB | DOI | WoS | PubMed | Europe PMC
Kloss R, Limberg MH, Mackfeld U, Hahn D, Grünberger A, Jaeger VD, Krauss U, Oldiges M, Pohl M (2018)
SCIENTIFIC REPORTS 8(1): 5856. -
2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2920685Inheritance of Cell-Cycle Duration in the Presence of Periodic ForcingPUB | DOI | WoS
Mosheiff N, Martins BMC, Pearl-Mizrahi S, Grünberger A, Helfrich S, Mihalcescu I, Kohlheyer D, Locke JCW, Glass L, Balaban NQ (2018)
PHYSICAL REVIEW X 8(2): 15. -
2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2932416Selective Pressure for Biofilm Formation in Bacillus subtilis: Differential Effect of Mutations in the Master Regulator SinR on BistabilityPUB | DOI | WoS | PubMed | Europe PMC
Kampf J, Gerwig J, Kruse K, Cleverley R, Dormeyer M, Grünberger A, Kohlheyer D, Commichau FM, Lewis RJ, Stuelke J (2018)
mBio 9(5): e01464-18. -
2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2932764
Germination and Growth Analysis of Streptomyces lividans at the Single-Cell Level Under Varying Medium CompositionsPUB | PDF | DOI | WoS | PubMed | Europe PMC
Koepff J, Sachs CC, Wiechert W, Kohlheyer D, Noeh K, Oldiges M, Grünberger A (2018)
FRONTIERS IN MICROBIOLOGY 9: 2680. -
2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2930515Natural biocide cocktails: Combinatorial antibiotic effects of prodigiosin and biosurfactantsPUB | DOI | WoS | PubMed | Europe PMC
Hage-Huelsmann J, Grünberger A, Thies S, Santiago-Schuebel B, Klein AS, Pietruszka J, Binder D, Hilgers F, Domroese A, Drepper T, Kohlheyer D, et al. (2018)
PLOS ONE 13(7): e0200940. -
2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2919078Quantitative modelling of nutrient-limited growth of bacterial colonies in microfluidic cultivationPUB | DOI | WoS | PubMed | Europe PMC
Hornung R, Grünberger A, Westerwalbesloh C, Kohlheyer D, Gompper G, Elgeti J (2018)
JOURNAL OF THE ROYAL SOCIETY INTERFACE 15(139): 11. -
2018 | Konferenzbeitrag | PUB-ID: 2933363Towards Microfluidic Single-Cell Cultivation of Mammalian Cell LinesPUB
Schmitz J, Noll T, Grünberger A (2018)
Presented at the Young Scientist Cell Culture Biotechnology Retreat, Laupheim. -
2018 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2933359Towards dynamic single-cell cultivation systems for industrially relevant mammalian cell linesPUB
Schmitz J, Kerkhoff Y, Noll T, Kohlheyer D, Grünberger A (2018)
Presented at the BioProcessing Days 2018, Recklinghausen. -
2018 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2933362Dynamic microfluidical single-cell cultivation of mammalian cell lines. From experiment to analysisPUB
Schmitz J, Kerkhoff Y, Noll T, Grünberger A (2018)
Presented at the CeBiTec Symposium 2018, Bielefeld. -
2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2932765Tailor-made catalytically active inclusion bodies for different applications in biocatalysisPUB | DOI | WoS
Kloss R, Karmainski T, Jaeger VD, Hahn D, Grünberger A, Baumgart M, Krauss U, Jaeger K-E, Wiechert W, Pohl M (2018)
CATALYSIS SCIENCE & TECHNOLOGY 8(22): 5816-5826. -
2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2931505A Synthetic Reaction Cascade Implemented by Colocalization of Two Proteins within Catalytically Active Inclusion BodiesPUB | DOI | WoS | PubMed | Europe PMC
Jaeger VD, Lamm R, Kloss R, Kaganovitch E, Grünberger A, Pohl M, Buechs J, Jaeger K-E, Krauss U (2018)
ACS SYNTHETIC BIOLOGY 7(9): 2282-2295. -
2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2919063Visualization of tandem repeat mutagenesis in Bacillus subtilisPUB | DOI | WoS | PubMed | Europe PMC
Dormeyer M, Lentes S, Ballin P, Wilkens M, Klumpp S, Kohlheyer D, Stannek L, Grünberger A, Commichau FM (2018)
DNA REPAIR 63: 10-15. -
2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912521Real-time monitoring of fungal growth and morphogenesis at single-cell resolutionPUB | DOI | WoS | PubMed | Europe PMC
Grünberger A, Schöler K, Probst C, Kornfeld G, Hardiman T, Wiechert W, Kohlheyer D, Noack S (2017)
Engineering in life sciences 17(1): 86–92. -
2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912738Coarse-graining bacteria colonies for modelling critical solute distributions in picolitre bioreactors for bacterial studies on single-cell levelPUB | DOI | WoS | PubMed | Europe PMC
Westerwalbesloh C, Grünberger A, Wiechert W, Kohlheyer D, von Lieres E (2017)
Microbial Biotechnology 10(4): 845-857. -
2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2916519Homogenizing bacterial cell factories: Analysis and engineering of phenotypic heterogeneityPUB | DOI | WoS | PubMed | Europe PMC
Binder D, Drepper T, Jaeger K-E, Delvigne F, Wiechert W, Kohlheyer D, Grünberger A (2017)
METABOLIC ENGINEERING 42: 145-156. -
2017 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912503Picoliter bioreactors for microbial consortia: From proof of concept to first applicationPUB
Rudat A, Wiechert W, Kohlheyer D, Grünberger A (2017)
Presented at the Himmelfahrtstagung 2017: Models for Developing and Optimising Biotech Production, Neu-Ulm, Germany. -
2017 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912508Microfluidic heterogeneity analysis of fluorescence-based gene expression of industrially relevant production strains on single-cell levelPUB
Burmeister A, Bitzenhofer NL, Grünberger A, Binder D, Drepper T, Wiechert W, Kohlheyer D (2017)
Presented at the BioProcessing Days 2017, Recklinghausen, Germany. -
2017 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912759Microfluidic Single-Cell Cultivation: A key for next generation bioprocess development?PUB
Grünberger A (2017)
Presented at the FFBiotech Symposium - Innovative approaches in bioreactors design and operation, Lille, France. -
2017 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912771Microfluidic single-cell (co-)cultivation: Exploring the next dimensionPUB
Rudat A, Noack S, Wiechert W, Kohlheyer D, Grünberger A (2017)
Presented at the Data-driven Biotechnology - bench, bioreactor and bedside, Copenhagen, Denmark. -
2017 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912502Functionally-active protein aggregates - towards the realization of an enzyme cascade in catalytically-active inclusion bodiesPUB
Jäger VD, Longerich S, Dietrich M, Kloss R, Grünberger A, Pohl M, Jaeger K-E, Krauss U (2017)
Presented at the BioTrans 2017, Budapest, Hungary. -
2017 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912505Microfluidic single-cell cultivation of S. lividans: Uncovering heterogeneity in filamentous growthPUB
Sachs CC, Koepff J, Kohlheyer D, Wiechert W, Oldiges M, Nöh K, Grünberger A (2017)
Presented at the DECHEMA-Tagung "Systems Biology meets Synthetic Biology", Frankfurt, Germany. -
2017 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912507Spatiotemporal analysis of synthetic microbial communities at the single-cell level in microfluidic interaction compartmentsPUB
Rudat A, Wiechert W, Kohlheyer D, Grünberger A (2017)
Presented at the 6th International Conference on Microbial Communication for Young Scientists, Jena, Germany. -
2017 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912501Catalytically active inclusion bodies. A novel carrier-free Enzyme Immobilisation methodPUB
Kloss R, Limberg M, Jäger VD, Mackfeld U, Karmainski T, Grünberger A, Krauss U, Pohl M (2017)
Presented at the BioTrans 2017, Budapest, Hungary. -
2017 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912506Integrated High-Throughput Platform for Microfluidic Live-Cell Analysis with Feed-Back EyperimentationPUB
Sachs CC, Grünberger A, Probst C, Wiechert W, Kohlheyer D, Nöh K (2017)
Presented at the DECHEMA-Tagung "Systems Biology meets Synthetic Biology", Frankfurt, Germany. -
2017 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2912518Microfluidic device for control and sensing of dynamic oxygen levels during cell cultivationPUB
Kaganovitch E, Krischer M, Probst C, Grünberger A, Zunic E, Freier C, Wiechert W, Kohlheyer D (2017)
In: 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2016). Red Hook, NY: Curran Associates, Inc.: 355-356. -
2017 | Sammelwerksbeitrag | Veröffentlicht | PUB-ID: 2912520Application of Mini- and Micro-Bioreactors for Microbial BioprocessesPUB | DOI
Ladner T, Grünberger A, Probst C, Kohlheyer D, Büchs J, Delvigne F (2017)
In: Current Developments in Biotechnology and Bioengineering. Larroche C, Sanromán MÁ, Du G, Pandey A (Eds); Amsterdam: Elsevier: 433-461. -
2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912737Taking control over microbial populations: Current approaches for exploiting biological noise in bioprocessesPUB | DOI | WoS | PubMed | Europe PMC
Delvigne F, Baert J, Sassi H, Fickers P, Grünberger A, Dusny C (2017)
Biotechnology Journal 12(7): 1600549. -
2017 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912504Models for Developing and Optimizing Microscale Bacteria CultivationPUB
Westerwalbesloh C, Grünberger A, Wiechert W, Kohlheyer D, von Lieres E (2017)
Presented at the Himmelfahrtstagung 2017: Models for Developing and Optimising Biotech Production, Neu-Ulm, Germany. -
2017 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912509Microfluidic cultivation chamber for the investigation of synthetic microbial co-cultures on single-cell level: From the development to first applicationPUB
Rudat A, Wiechert W, Kohlheyer D, Grünberger A (2017)
Presented at the BioProcessing Days 2017, Recklinghausen, Germany. -
2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912514
Comparative Single-Cell Analysis of Different E. coli Expression Systems during Microfluidic CultivationPUB | PDF | DOI | WoS | PubMed | Europe PMC
Binder D, Probst C, Grünberger A, Hilgers F, Loeschcke A, Jaeger K-E, Kohlheyer D, Drepper T (2016)
PLoS one 11(8): e0160711. -
2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912522
Image-Based Single Cell Profiling: High-Throughput Processing of Mother Machine ExperimentsPUB | PDF | DOI | WoS | PubMed | Europe PMC
Sachs CC, Grünberger A, Helfrich S, Probst C, Wiechert W, Kohlheyer D, Nöh K (2016)
PLoS one 11(9): e0163453. -
2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912513Optogenetic Regulation of Tunable Gene Expression in Yeast Using Photo-Labile Caged MethioninePUB | DOI | WoS | PubMed | Europe PMC
Kusen PM, Wandrey G, Probst C, Grünberger A, Holz M, Meyer zu Berstenhorst S, Kohlheyer D, Büchs J, Pietruszka J (2016)
ACS chemical biology 11(10): 2915-2922. -
2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912527Microfluidic single-cell cultivation: Is small the new beautiful?PUB
Grünberger A (2016)
Presented at the 6th International Bielefeld-CeBiTec Research Conference: Advances in Industrial Biotechnology: New Techniques, Substrates and Products for Bioprocesses, Bielefeld, Germany. -
2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912534Single-cell microfluidics for bioprocess developmentPUB
Grünberger A (2016)
Presented at the GreenWin Conferences “Green Chemistry and White Biotechnology", Gembloux, Belgium. -
2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912539Nutrient distribution in perfusion based picoliter bioreactorsPUB
Westerwalbesloh C, Grünberger A, Stute B, Weber S, Wiechert W, Kohlheyer D, von Lieres E (2016)
Presented at the 4th BioProScale Symposium "Bioprocess intensification through process analytical technology (PAT) and quality by design (QbD)", Berlin, Germany. -
2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912820Combinatorial antibiotic effects of natural biocide cocktailsPUB
Hage-Hülsmann J, Grünberger A, Thies S, Domröse A, Klein A, Binder D, Hilgers F, Kohlheyer D, Pietruszka J, Jaeger K-E, Drepper T, et al. (2016)
Presented at the IV International Conference on Antimicrobial Research, Malaga, Spain. -
2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912761Microfluidic single-cell bioreactors. Introduction, application and future perspectivesPUB
Grünberger A (2016)
Presented at the LCSB Biannual Minisymposia in Modelling/Automation/Microfluidics at the University of Luxembourg, Esch-sur-Alzette, Luxembourg. -
2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912803Employing photocaged carbohydrates in light-controlled cell factories for synthetic bio(techno)logy and single cell applicationsPUB
Binder D, Bier C, Grünberger A, Hilgers F, Loeschcke A, Kohlheyer D, Pietruszka J, Jaeger KE, Drepper T (2016)
Presented at the Annual Conference of the Association for General and Applied Microbiology (VAAM),, Jena, Germany. -
2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912512Sugar Based Caged Compounds for Biotechnological Synthetic Biological ApplicationsPUB
Bier C, Binder D, Grünberger A, Drobietz D, Hage-Hülsmann J, Kohlheyer D, Löschcke A, Jaeger K-E, Drepper T, Pietruszka J (2016)
Presented at the 26th IUPAC Symposium on Photochemistry, Osaka, Japan. -
2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912524Microfluidic cultivation of the microalgae Chlorella sorokiniana on single-cell level at defined environmentsPUB
Brehl C, Grünberger A, Probst C, Pfaff C, Wiechert W, Behrendt D, Kohlheyer D (2016)
Presented at the 9. DECHEMA Bundesalgenstammtisch, Jülich, Germany. -
2016 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 2912526Comparison of different cultivation chamber designs for microfluidic bioreactorsPUB | DOI
Westerwalbesloh C, Grünberger A, Wiechert W, Kohlheyer D, von Lieres E (2016)
Chemie Ingenieur Technik 88(9): 1390. -
2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912529Microbial metabolic state diagrams: Using microfluidic single-cell cultivation to predict bacterial gene expresssionPUB
Grünberger A, Steffens I, Binder D, Drepper T, Wiechert W, Kohlheyer D (2016)
Presented at the EMBL Conference Microfluidics, Heidelberg, Germany. -
2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912531Modeling inhomogeneities across cultivation chamber arrays in single-cell cultivation devicesPUB
Westerwalbesloh C, Grünberger A, Kohlheyer D, von Lieres E (2016)
Presented at the EMBL Conference Microfluidics, Heidelberg (Germany. -
2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912536An integrated platform for dynamic microfluidic experimentation with single-cell resolutionPUB
Sachs CC, Probst C, Grünberger A, Wiechert W, Frunzke J, Kohlheyer D, Nöh K (2016)
Presented at the DECHEMA-Tagung 'Single Cell Technologies 2016', Frankfurt, Germany. -
2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912538Bacterial phase diagrams. Analyzing and predicting cell-to-cell heterogeneity of microbial gene expressionPUB
Steffens I, Grünberger A, Binder D, Drepper T, Wiechert W, Kohlheyer D (2016)
Presented at the 4th BioProScale Symposium "Bioprocess intensification through process analytical technology (PAT) and quality by design (QbD)", Berlin (Germany). -
2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912540Bacterial phase diagrams – Using engineering concepts to predict cell-to-cell heterogeneity of microbial gene expressionPUB
Grünberger A, Steffens I, Binder D, Drepper T, Wiechert W, Kohlheyer D (2016)
Presented at the Jahrestagung 2016 der Vereinigung für Allgemeine und Angewandte Mikrobiologie, Jena, Germany. -
2016 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2912552Closing the gap between microfluidic single-cell analysis and bioprocess development for microbial organismsPUB
Probst C, Freier C, Mahr R, Grünberger A, Helfrich S, Wiechert W, Nöh K, Frunzke J, Kohlheyer D (2016)
In: 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2015). Red Hook, NY: Curran Associates, Inc.: 537-539. -
2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912525Microfluidic heterogeneity analysis of fluorescence-based gene expression of industrially relevant production strains on single-cell levelPUB
Burmeister A, Bitzenhofer NL, Grünberger A, Binder D, Drepper T, Wiechert W (2016)
Presented at the 18. Heiligenstädter Kolloquium „Technische Systeme für die Lebenswissenschaften, Heiligenstadt, Germany. -
2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912532Characterizing substrate availability within microfluidic tools employed for the analysis of genetically modified single cellsPUB
Westerwalbesloh C, Grünberger A, Stute B, Weber S, Kohlheyer D, von Lieres E (2016)
Presented at the 1. International Conference on Molecular Interaction Engineering (MIE), Karlsruhe, Germany. -
2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912537Bioprocesses under magnification. Learning from single cells about large-scale processesPUB
Grünberger A, Wiechert W, Kohlheyer D (2016)
Presented at the 4th BioProScale Symposium "Bioprocess intensification through process analytical technology (PAT) and quality by design (QbD)", Berlin, Germany. -
2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912544Photocaged Arabinose - A Novel Optogenetic Switch for Rapid and Gradual Control of Microbial Gene ExpressionPUB | DOI | WoS | PubMed | Europe PMC
Binder D, Bier C, Grünberger A, Drobietz D, Hage-Hülsmann J, rey G, Büchs J, Kohlheyer D, Loeschcke A, Wiechert W, Jaeger K-E, et al. (2016)
ChemBioChem 17(4): 296-299. -
2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912739Enhanced protein and biochemical production using CRISPRi-based growth switchesPUB | DOI | WoS | PubMed | Europe PMC
Li S, Jendresen CB, Grünberger A, Ronda C, Jensen SI, Noack S, Nielsen AT (2016)
Metabolic Engineering 38: 274-284. -
2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912760Picoliter bioreactors for microbial consortia: A novel concept to investigate microbial interactions at the single-cell levelPUB
Grünberger A (2016)
Presented at the SynComBio Workshop “Applications of synthetic microbial communities in bioeconomy", Düsseldorf, Germany. -
2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912772Spatio-temporal analysis of bacterial populations at single-cell levelPUB
Grünberger A, Sachs C, Kohlheyer D, Wiechert W, Nöh K (2016)
Presented at the IBG Modelling Workshop, Jülich, Germany. -
2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912511Photocaged Carbohydrates: Versatile Tools for Biotechnological ApplicationsPUB
Bier C, Binder D, Grünberger A, Drobietz D, Kohlheyer D, Löschcke A, Jaeger K-E, Drepper T, Pietruszka J (2016)
Presented at the 18th International Conference on Photochemistry, Paris, France. -
2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912523Microfluidic cultivation of the microalgae Chlorella sorokiniana on single-cell level at defined environmentsPUB
Brehl C, Grünberger A, Probst C, Pfaff C, Wiechert W, Behrendt D, Kohlheyer D (2016)
Presented at the ProcessNet 2016, Aachen, Germany. -
2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912530Single-cell analysis of E. coli in microfluidic batch reactorsPUB
Kaganovitch E, Probst C, Westerwalbesloh C, Grünberger A, Wiechert W, Kohlheyer D (2016)
Presented at the EMBL Conference Microfluidics, Heidelberg (Germany. -
2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912535Bacterial phase diagrams: A novel concept to predict and control bacterial gene expressionPUB
Grünberger A, Steffens I, Binder D, Drepper T, Wiechert W, Kohlheyer D (2016)
Presented at the DECHEMA-Himmelfahrtstagung: New Frontiers for Biotech Processes, Koblenz, Germany. -
2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2904866Light-controlled cell factories – Employing photocaged IPTG for light-mediated optimization of lac-based gene expression and (+)-valencene biosynthesis in Corynebacterium glutamicumPUB | DOI | WoS | PubMed | Europe PMC
Binder D, Frohwitter J, Mahr R, Bier C, Grünberger A, Loeschcke A, Peters-Wendisch P, Kohlheyer D, Pietruszka J, Frunzke J, Jaeger K-E, et al. (2016)
Appl Environ Microbiol 82(20): 6141-6149. -
2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912568Technical bias of microcultivation environments on single cell physiologyPUB | DOI | WoS | PubMed | Europe PMC
Dusny C, Grünberger A, Probst C, Wiechert W, Kohlheyer D, Schmid A (2015)
Lab on a chip 15(8): 1822-1834. -
2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912584Rapid inoculation of single bacteria into parallel picoliter fermentation chambersPUB | DOI | WoS
Probst C, Grünberger A, Braun N, Helfrich S, Nöh K, Wiechert W, Kohlheyer D (2015)
Analytical methods 7(1): 91-98. -
2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912550Spatiotemporal microbial single-cell analysis using a high-throughput microfluidics cultivation platformPUB | DOI | WoS | PubMed | Europe PMC
Grünberger A, Probst C, Helfrich S, Nanda A, Stute B, Wiechert W, von Lieres E, Nöh K, Frunzke J, Kohlheyer D (2015)
Cytometry / A 87(12): 1101–1115. -
2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912554
Non-Invasive Microbial Metabolic Activity Sensing at Single Cell Level by Perfusion of Calcein Acetoxymethyl EsterPUB | PDF | DOI | WoS | PubMed | Europe PMC
Krämer CEM, Singh A, Helfrich S, Grünberger A, Wiechert W, Nöh K, Kohlheyer D (2015)
PLoS one 10(10): e0141768. -
2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912555Vizardous: interactive analysis of microbial populations with single cell resolutionPUB | DOI | WoS | PubMed | Europe PMC
Helfrich S, Azzouzi CE, Probst C, Seiffarth J, Grünberger A, Wiechert W, Kohlheyer D, Nöh K (2015)
Bioinformatics 31(23): 3875-3877: btv468. -
2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912557
Modeling and CFD Simulation of nutrient Distribution in picoliter bioreactors for bacterial growth studies on single-cell levelPUB | PDF | DOI | WoS | PubMed | Europe PMC
Westerwalbesloh C, Grünberger A, Stute B, Weber S, Wiechert W, Kohlheyer D, von Lieres E (2015)
Lab on a chip 15(21): 4177-4186. -
2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912541Light-controlled cell factories - Employing optogenetic plug-and-play expression modules based on photocaged carbohydrates for synthetic bio(techno)logy and single cell applicationsPUB
Binder D, Bier C, Grünberger A, Loeschcke A, Kohlheyer D, Pietruszka J, Jaeger K-E, Drepper T (2015)
Presented at the ESP Photobiology conference, Aveiro, Portugal. -
2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912546Single-cell microfluidics: A key technology to understand life at environmental defined conditionsPUB
Grünberger A, Wiechert W, Kohlheyer D (2015)
Presented at the Kick-off Konferenz: Leben? - Eine neue Förderinitiative stellt sich vor, Hannover, Germany. -
2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912560Dynamic environmental control in microfluidic devices for single-cell Analysis of biological production processesPUB
Zunic E, Schechtel A, Probst C, Grünberger A, Freier C, Seibold G, Wiechert W, Kohlheyer D (2015)
Presented at the Kolloquium Synthetic Biology - Opportunities for Interdisciplinary Research from Biology to Engineering, Aachen, Germany. -
2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912565Single-cell microfluidics meets applied biotechnology. From expectation to applicationPUB
Grünberger A, Probst C, Frunzke J, Noack S, Wiechert W, Kohlheyer D (2015)
Presented at the Conference "Cell Factories and Biosustainability - Technologies for Cell Factory Construction", Hillerod, Denmark. -
2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912773Single-cell microfluidics meets applied biotechnology. From expectation to applicationPUB
Grünberger A, Probst C, Frunzke J, Noack S, Wiechert W, Kohlheyer D (2015)
Presented at the Jahreskongress Biotechnologie 2020+, Berlin, Germany. -
2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912545Heterologous production of antibacterial secondary metabolites from Serratia marcescens in Pseudomonas putidaPUB
Loeschcke A, Thies S, Hage-Hülsmann J, Grünberger A, Binder D, Domröse A, Klein A, Kohlheyer D, Pietruszka J, Jaeger K-E, Drepper T (2015)
Presented at the 6th Congress of European Microbiologists (FEMS 2015), Maastricht, Netherlands. -
2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912548Caged Compounds for Biotechnological and Synthetic Biological ApplicationsPUB
Bier C, Binder D, Grünberger A, Drobietz D, Hage-Hülsmann J, Kohlheyer D, Loeschke A, Jaeger K-E, Drepper T, Pietruszka J (2015)
Presented at the European Society for Photobiology 2015 Congress, Aveiro, Portugal. -
2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912562Einzelzell-Bioreaktoren - fast unsichtbar, aber nicht unscheinbarPUB | DOI
Grünberger A (2015)
Biospektrum 21(3): 353-353. -
2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912567Single-cell bioreactors: Improving the understanding of microbial metabolismPUB
Grünberger A (2015)
Presented at the 30. Jahrestagung der Vereinigung für Allgemeine und Angewandte Mikrobiologie, Marburg (Germany. -
2015 | Dissertation | Veröffentlicht | PUB-ID: 2912574
Single-Cell Analysis of Microbial Production Strains in Microfluidic BioreactorsPUB | PDF
Grünberger A (2015) Schriften des Forschungszentrums Jülich. Reihe Schlüsseltechnologien / Key Technologies; 114.
Jülich: RWTH Aachen. -
2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912549Metabolite biosensors for single cell Analysis and the Evolution of production strainsPUB
Mahr R, Mustafi N, Grünberger A, Helfrich S, Nöh K, Kohlheyer D, Frunzke J (2015)
Presented at the 30. Jahrestagung der Vereinigung für Allgemeine und Angewandte Mikrobiologie, Marburg, Germany. -
2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912551Genetically encoded sensor analysis with spatial and temporal Resolution by time-lapse imagingPUB
Probst C, Grünberger A, Krämer C, Sachs CC, Wiechert W, Baumgart M, Kohlheyer D (2015)
Presented at the 1st Evaluation Symposium, Molecular Interaction Engineering, MIE-Project, Karlsruhe, Germany. -
2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912556Lichtgesteuerte Genexpression auf EinzelzellebenePUB | DOI
Binder D, Probst C, Bier C, Loeschcke A, Grünberger A (2015)
Biospektrum 21(6): 612-615. -
2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912563High-throughput, long-term growth characterization of C. glutamicum on single cell level using the Mother MachinePUB
Sachs CC, Helfrich S, Grünberger A, Probst C, Wiechert W, Kohlheyer D, Nöh K (2015)
Presented at the 3rd International Conference of the Cluster of Excellence Tailor-Made Fuels from Biomass, Aachen, Germany. -
2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912804Instantaneous microfluidic metabolic activity sensing for non-invasive single cell physiology analysis of a prokaryote and its descendantsPUB
Krämer C, Helfrich S, Singh A, Grünberger A, Wiechert W, Nöh K, Kohlheyer D (2015)
Presented at the 3nd International Conference IMPLEMENTATION OF MICROREACTOR TECHNOLOGY INTO BIOTECHNOLOGY (IMTB 2015), Opatija, Croatia. -
2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912763Microfluidic Single-Cell Cultivation: The key for next generation bioprocess development?PUB
Grünberger A (2015)
Presented at the Colloquium Biotechnology, Technical Faculty - Bielefeld University, Bielefeld. -
2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912542Optical control of gene expression in bacteria on the single-cell level by caged compoundsPUB
Probst C, Grünberger A, Binder D, Steffen I, Wiechert W, Kohlheyer D (2015)
Presented at the Synthetic Biology: Opportunities for Interdisciplinary Research from Biology to Engineering, Aachen, Germany. -
2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912559High-throughput long-term growth characterization of C. glutamicum on single cell using the Mother MachinePUB
Sachs CC, Helfrich S, Grünberger A, Probst C, Wiechert W, Kohlheyer D, Nöh K (2015)
Presented at the Colloquium Synthetic Biology - Opportunities for Interdisciplinary Research from Biology to Engineering, Aachen, Germany. -
2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912566Single-Cell Bioreactors: Cutting Edge Cultivation Devices for the Ultimate Scale-Down of BioprocessesPUB
Grünberger A, Probst C, Wiechert W, Kohlheyer D (2015)
Presented at the DECHEMA-Himmelfahrtstagung "Scale-up and scale-down of bioprocesses", Hamburg-Bergedorf, Germany. -
2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912605Taking Control over Control: Use of Product Sensing in Single Cells to Remove Flux Control at Key Enzymes in Biosynthesis PathwaysPUB | DOI | WoS | PubMed | Europe PMC
Schendzielorz G, Dippong M, Grünberger A, Kohlheyer D, Yoshida A, Binder S, Nishiyama C, Nishiyama M, Bott M, Eggeling L (2014)
ACS Synthetic Biology 3(1): 21–29. -
2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912573
Application of a Genetically Encoded Biosensor for Live Cell Imaging of L-Valine Production in Pyruvate Dehydrogenase Complex-Deficient Corynebacterium glutamicum StrainsPUB | PDF | DOI | WoS | PubMed | Europe PMC
Mustafi N, Grünberger A, Mahr R, Helfrich S, Nöh K, Blombach B, Kohlheyer D, Frunzke J (2014)
PLoS one 9(1): e85731. -
2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912594
Light-responsive control of bacterial gene Expression: precise triggering of the lac promoter activity using photocaged IPTGPUB | PDF | DOI | WoS | PubMed | Europe PMC
Binder D, Grünberger A, Loeschcke A, Probst C, Bier C, Pietruszka J, Wiechert W, Kohlheyer D, Jaeger K-E, Drepper T (2014)
Integrative biology 6(8): 755-765. -
2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912589Microfluids as platform for the spatiotemporal analysis of bacterial populations at single-cell levelPUB
Helfrich S, Krämer C, Grünberger A, Azzouzi CE, Pfeifer E, Frunzke J, Wiechert W, Kohlheyer D, Nöh K (2014)
Presented at the 30th Symposium "Mechanisms of Gene Regulation" of the VAAM study group "Regulation & Signal Transduction in Prokaryotes", Düsseldorf, Germany. -
2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912591Microfluidic Single-Cell Cultivation: Opportunity for Industrial Bioprocess DevelopmentPUB
Grünberger A, Probst C, Frunzke J, Noack S, Wiechert W, Kohlheyer D (2014)
Presented at the EMBL Conference – Microfluidics 2014, Heidelberg, Germany. -
2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912596Single-cell cultivation in picoliter scale: Opportunity for bioprocess developmentPUB
Grünberger A, Probst C, Unthan S, Mustafi N, Frunzke J, Noack S, Wiechert W, Kohlheyer D (2014)
Presented at the 3rd BioProScale Symposium, Berlin, Germany. -
2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912616Beyond growth rate 0.6. What drives Corynebacterium glutamicum to higher growth rates in defined mediumPUB | DOI | WoS | PubMed | Europe PMC
Unthan S, Grünberger A, van Ooyen J, Gätgens J, Heinrich J, Paczia N, Wiechert W, Kohlheyer D, Noack S (2014)
Biotechnology and bioengineering 111(2): 359–371. -
2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912806Cage me if you can! Optogenetic bacterial gene regulation using photocaged inducersPUB
Binder D, Grünberger A, Loeschcke A, Probst C, Bier C, Pietruszka J, Wiechert W, Kohlheyer D, Jäger K-E, Drepper T (2014)
Presented at the 30th Symposium „Mechanisms of gene regulation”, Düsseldorf, Germany. -
2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912730
Analysis of SOS-Induced Spontaneous Prophage Induction in Corynebacterium glutamicum at the Single-Cell LevelPUB | PDF | DOI | WoS | PubMed | Europe PMC
Nanda AM, Heyer A, Kramer C, Grünberger A, Kohlheyer D, Frunzke J (2014)
Journal of Bacteriology 196(1): 180-188. -
2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912766Picoliter Bioreactors. Learning from Single Cells about Large Scale ProcessesPUB
Grünberger A (2014)
Presented at the iGEM Meetup, Aachen, Germany. -
2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912805Microfluidic Single-Cell Analysis – Potential for Microalgae Research?PUB
Kohlheyer D, Grünberger A, Weber S, Nedbal L, Wiechert W (2014)
Presented at the BioSC Workshop | Exploration "Perspectives of Algal Technologies", Jülich, Germany. -
2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912808Metabolite biosensors for single cell analysis and the development of production strainsPUB
Mahr R, Mustafi N, Grünberger A, Helfrich S, Nöh K, Kohlheyer D, Frunzke J (2014)
Presented at the 30th Symposium „Mechanisms of gene regulation”, Düsseldorf, Germany. -
2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912569Cage me if you can! Optogenetic bacterial gene regulation using photocaged inducersPUB
Binder D, Grünberger A, Loeschcke A, Probst C, Bier C, Pietruszka J, Wiechert W, Kohlheyer D, Jaeger K-E, Drepper T (2014)
Presented at the VAAM Jahrestagung, Dresden, Germany. -
2014 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2912571Microfluidic Single-Cell Analysis Platform for Biotechnological Process DevelopmentPUB
Grünberger A, Probst C, Helfrich S, Frunzke J, Noack S, Nöh K, Wiechert W, Kohlheyer D (2014)
In: MicroTAS 2014. San Diego, California: CBM Society: 3 p. -
2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912576From extracellular Environment to functional phenotype. Quantitative comparison of single cell physiology in static and steady environmentsPUB
Dusny C, Grünberger A, Wiechert W, Kohlheyer D, Schmid A (2014)
Presented at the 3rd BioProScale Symposium "Inhomogeneities in large-scale bioprocesses. System biology and process dynamics", Berlin, Germany. -
2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912583Picoliter Bioreactors. Learning from Single Cells about Large-Scale BioprocessesPUB
Grünberger A, Probst C, Wiechert W, Kohlheyer D (2014)
Presented at the 24th Annual conference of the German Society for Cytometry, Dresden, Germany. -
2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912586Microbial Populations on the Microfluidic Analyst's Couch: Approaching Cellular HeterogeneityPUB
Helfrich S, Azzouzi CE, Krämer C, Pfeifer E, Grünberger A, Mustafi N, Wiechert W, Frunzke J, Kohlheyer D, Nöh K (2014)
Presented at the BioImage Informatics 2014, Leuven, Belgium. -
2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912588Investigating single-cell growth of microbial cell factories: is counting cells enough?PUB
Helfrich S, Grünberger A, Kohlheyer D, Wiechert W, Nöh K (2014)
Presented at the 2nd International Workshop on Image-based Systems Biology, Jena (Germany. -
2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912590Transcription factor-based biosensor for microbial strain developmentPUB
Mahr R, Mustafi N, Grünberger A, Helfrich S, Nöh K, Kohlheyer D, Frunzke J (2014)
Presented at the 30th Symposium "Mechanisms of Gene Regulation" of the VAAM study group "Regulation & Signal Transduction in Prokaryotes", Düsseldorf, Germany. -
2014 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 2912593Systematic screening of single-cell growth and production in a picoliter cultivation platformPUB | DOI
Grünberger A, Unthan S, Mahr R, Frunzke J, Noack S, Wiechert W, Kohlheyer D (2014)
Chemie Ingenieur Technik 86(9): 1408. -
2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912595Single-cell Bioreactors boost Bioprocess Development: New Insights into Cellular MetabolismPUB
Kohlheyer D, Grünberger A, Probst C, Helfrich S, Frunzke J, Eggeling L, Nöh K, Noack S, Wiechert W (2014)
Presented at the Metabolic Engineering X, Vancouver, Canada. -
2014 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2912601Simple microfluidics for complex organisms: A microfluidic chip System for growth and Morphogenesis studies of filamentous fungiPUB
Grünberger A, Schmitz K, Probst C, Noack S, Wiechert W, Kohlheyer D (2014)
In: 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2013). Red Hook, NY: Curran. -
2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912575Microfluidics as platform for the spatiotemporal analysis of bacterial populations at single-cell levelPUB
Krämer C, Helfrich S, Azzouzi CE, Grünberger A, Pfeifer E, Frunzke J, Wiechert W, Nöh K, Kohlheyer D (2014)
Presented at the International Meeting, Phenotypic heterogeneity and sociobiology of bacterial populations, Irsee, Germany. -
2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912582Microfluidic Single-Cell Cultivation Systems: Versatile Tools for MicrobiologyPUB
Grünberger A, Probst C, Nanda A, Frunzke J, Wiechert W, Kohlheyer D (2014)
Presented at the 4th Annual Conference of the Association for General and Applied Microbiology, Dresden, Germany. -
2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912587Metabolite biosensors for single cell analysis and the development of production strainsPUB
Mahr R, Mustafi N, Grünberger A, Helfrich S, Nöh K, Kohlheyer D, Frunzke J (2014)
Presented at the Gemeinsame Jahrestagung der Deutschen Gesellschaft für Hygiene und Mikrobiologie und der Vereinigung für Allgemeine und Angewandte Mikrobiologie, Dresden, Germany. -
2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912823Application of a genetically-encoded metabolite sensor for single cell analysis and development of production strainsPUB
Mahr R, Mustafi N, Grünberger A, Helfrich S, Nöh K, Kohlheyer D, Frunzke J (2014)
Presented at the Metabolic engineering X, Vancouver, Canada. -
2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912814Introduction into Microfluidic Single-Cell AnalysisPUB
Grünberger A, Probst C (2014)
Presented at the Biology feat, Engineering – SYNBIO – Single Cell Analysis in Microfluidic Devices (Workshop), Jülich, Germany. -
2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912580Quantitative Physiology of Single Cells for Linking Phenotype and EnvironmentPUB
Dusny C, Grünberger A, Rosenthal K, Wiechert W, Schmid A (2014)
Presented at the 24th Annual Conference of the German Society for Flow Cytometry, Dresden, Germany. -
2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912585Robust Automated Image Analysis of Mother Machine Microfluidic Growth DevicesPUB
Sachs CC, Grünberger A, Wiechert W, Nöh K, Kohlheyer D (2014)
Presented at the BioImage Informatics 2014, Leuven, Belgium. -
2014 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 2912592Optimizing growth performance of Corynebacterium glutamicum at the single-cell levelPUB | DOI
Weber S, Grünberger A, Probst C, Wiechert W, Kohlheyer D (2014)
Chemie Ingenieur Technik 88(9): 1414. -
2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912597Single-cell microfluidics: opportunity for bioprocess developmentPUB | DOI | WoS | PubMed | Europe PMC
Grünberger A, Wiechert W, Kohlheyer D (2014)
Current opinion in biotechnology 29: 15-23. -
2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912599
Microfluidic Picoliter Bioreactor for Microbial Single-cell Analysis: Fabrication, System Setup, and OperationPUB | PDF | DOI | WoS | PubMed | Europe PMC
Grünberger A, Probst C, Heyer A, Wiechert W, Frunzke J, Kohlheyer D (2013)
Journal of visualized experiments. Bioengineering 82(82): e50560. -
2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912606Visualization of Imbalances in Sulfur Assimilation and Synthesis of Sulfur-Containing Amino Acids at the Single-Cell LevelPUB | DOI | WoS | PubMed | Europe PMC
Hoffmann K, Grünberger A, Lausberg F, Bott M, Eggeling L (2013)
Applied and environmental microbiology 79(21): 6730-6736. -
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912604Application of a genetically encoded biosensor for single cell analysis and strain development of production strainsPUB
Mahr R, Mustafi N, Grünberger A, Helfrich S, Nöh K, Kohlheyer D, Frunzke J (2013)
Presented at the New concepts and approaches in microbiology, Heidelberg, Germany. -
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912609Single-cell Dynamics of the SOS Response in Corynebacterium glutamicumPUB
Nanda A, Heyer A, Grünberger A, Helfrich S, Kohlheyer D, Nöh K, Frunzke J (2013)
Presented at the Bacterial Networks, Pultusk, Poland. -
2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912611
Polydimethylsiloxane (PDMS) Sub-Micron Traps for Single-Cell Analysis of BacteriaPUB | PDF | DOI | WoS
Probst C, Grünberger A, Wiechert W, Kohlheyer D (2013)
Micromachines 4(4): 357-369. -
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912623Spontaneous prophage induction in Corynebacterium glutamicumPUB
Heyer A, Nanda A, Grünberger A, Kohlheyer D, Frunzke J (2013)
Presented at the VAAM-Tagung 2013, Bremen, Germany. -
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912630Microbial single cell analysis of production strains in microfabricated habitatsPUB
Kohlheyer D, Grünberger A, Probst C, Krämer C, Eggeling L, Frunzke J, Wiechert W (2013)
Presented at the DECHEMA-Workshop Microfluidics for Systems Biology and Bioprocess Development, Frankfurt, Germany. -
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912825Characterization of light-triggered gene expression in E. coli with respect to population and single cell responsePUB
Binder D, Grünberger A, Loeschcke A, Probst C, Pietruszka J, Wiechert W, Kohlheyer D, Jaeger KE, Drepper T (2013)
Presented at the Jülich Biotech Day, Jülich, Germany. -
2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912745Coarse-Grained Modeling of Protein Second Osmotic Virial Coefficients: Sterics and Short-Ranged AttractionsPUB | DOI | WoS | PubMed | Europe PMC
Grünberger A, Lai P-K, Blanco MA, Roberts CJ (2013)
The Journal of Physical Chemistry B 117(3): 763-770. -
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912810Analysis of microbial observables on single cell level: Challenges of Cell Clusters for Microscopy-based Image ProcessingPUB
Helfrich S, Grünberger A, Kohlheyer D, Wiechert W, Nöh K (2013)
Presented at the 9th European Congress of Chemical Engineering (ECCE9)/ 2nd European Congress of Applied Biotechnology (ECAB2), The Hague, Netherlands. -
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912824Single-cell dynamics of the SOS response in Corynebacterium glutamicumPUB
Nanda AM, Heyer A, Grünberger A, Helfrich S, Kohlheyer D, Nöh K, Frunzke J (2013)
Presented at the Jülich Biotech Day, Jülich, Germany. -
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912827Application of a genetically- encoded metabolite sensor for single cell analysis and the development of production strainsPUB
Mahr R, Mustafi N, Grünberger A, Helfrich S, Nöh K, Kohlheyer D, Frunzke J (2013)
Presented at the Jülich Biotech Day, Jülich, Germany. -
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912829Automated image analysis pipeline for single cell bacterial growth studiesPUB
Sachs C, Grünberger A, Probst C, Wiechert W, Kohlheyer D (2013)
Presented at the Advanced Imaging in Cell- and Microbiology: Technology and Applications (AICMB), Jülich, Germany. -
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912834Characterization of light-triggered gene expression in E. coli with respect to population and single cell responsePUB
Binder D, Grünberger A, Loeschcke A, Probst C, Pietruszka J, Wiechert W, Kohlheyer D, Jaeger KE, Drepper T (2013)
Presented at the Advanced Imaging in Cell- and Microbiology: Technology and Applications (AICMB), Jülich, Germany. -
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912836Characterization of light-triggered gene expression in E. coli with respect to population and single cell responsePUB
Binder D, Grünberger A, Loeschcke A, Probst C, Pietruszka J, Wiechert W, Kohlheyer D, Jaeger KE, Drepper T (2013)
Presented at the New Approaches and Concepts in Microbiology, Heidelberg, Germany. -
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912603Single Cell Bioreactors for Bioprocess OptimizationPUB
Grünberger A, Probst C, Unthan S, Krämer C, Paczia N, Noack S, Wiechert W, Kohlheyer D (2013)
Presented at the Jülich Biotech Day 2013, Jülich,Germany. -
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912608SOS-induced spontaneous prophage induction in Corynebacterium glutamicumPUB
Nanda A, Heyer A, Krämer C, Grünberger A, Kohlheyer D, Frunzke J (2013)
Presented at the Jülich Biotech Day 2013, Jülich, Germany. -
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912613Microfluidic cultivation technology and application: analysing single-microbes under perfect environmental controlPUB
Probst C, Grünberger A, Frunzke J, Wiechert W, Kohlheyer D (2013)
Presented at the EMBL Heidelberg "New Approaches and Concepts in Microbiology", Heidelberg, Germany. -
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912615Explorative Analysis of Cell Population Development: Customizable Interactive Lineage TreesPUB
Helfrich S, Azzouzi CE, Grünberger A, Wiechert W, Nöh K (2013)
Presented at the EMBL Heidelberg "New Approaches and Concepts in Microbiology", Heidelberg, Germany. -
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912618Picoliter fermentation with single bacteria: Learning from the one to unravel the crowdPUB
Kohlheyer D, Grünberger A, Probst C, Frunzke J, Wiechert W (2013)
Presented at the 2nd International Congress Implementation of Microreactor Technology in Biotechnology, Cavtat, Croatia. -
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912620Increasing biomass productivity of C. glutamicum - new insights from microscale cultivationsPUB
Noack S, Grünberger A, van Ooyen J, Kohlheyer D, Wiechert W (2013)
Presented at the 9th European Congress of Chemical Engineering, Den Haag, The Netherlands. -
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912622Picoliter Bioreactors. Learning from Single Cells about Large Scale ProcessesPUB
Wiechert W, Kohlheyer D, Noack S, Frunzke J, Mustafi N, Grünberger A (2013)
Presented at the Copenhagen Bioscience Conferences, Cell Factories and Biosustainability, Favrholm, Denmark. -
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912625Single cell growth under constant environmental conditions and defined C sources: A case study for Corynebacterium glutamicumPUB
Heinrich J, Grünberger A, Probst C, Wiechert W, Kohlheyer D (2013)
Presented at the VAAM-Tagung 2013, Bremen, Germany. -
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912627Time lapse microbial single cell analysis in a micro fabricated batch reactorPUB
Probst C, Frank P, Grünberger A, Wiechert W, Kohlheyer D (2013)
Presented at the Single Cell Analysis Europe 2013, Barcelona, Spain. -
2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2614036Construction of a prophage-free variant of Corynebacterium glutamicum ATCC 13032 - a platform strain for basic research and industrial biotechnologyPUB | DOI | WoS | PubMed | Europe PMC
Baumgart M, Unthan S, Rückert C, Sivalingam J, Grünberger A, Kalinowski J, Bott M, Noack S, Frunzke J (2013)
Applied and environmental microbiology 79(19): 6006-6015. -
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912602Automated High-Throughput Time-Lapse Microscopy of Bacteria Microcolonies in Parallelized Monolayer Growth ChambersPUB
Grünberger A, Helfrich S, Mustafi N, Probst C, Frunzke J, Nöh K, Wiechert W, Kohlheyer D (2013)
Presented at the Advanced Imaging in Cell- and Microbiology: Technology and Applications, Jülich, Germany. -
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912607SOS-induced spontaneous prophage induction in Corynebacterium glutamicumPUB
Nanda A, Heyer A, Krämer C, Grünberger A, Kohlheyer D, Frunzke J (2013)
Presented at the Nikon Symposium on Advanced Imaging in Cell- and Microbiology Technology and Applications, Jülich, Germany. -
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912614Continuous Non-Invasive Real-Time Viability Measurement of Bacteria on Single Cell Level in Microfluidic Chip CulturesPUB
Krämer C, Grünberger A, Probst C, Wiechert W, Kohlheyer D (2013)
Presented at the EMBL Heidelberg "New Approaches and Concepts in Microbiology", Heidelberg, Germany. -
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912619Femtoliter chemostat for long-term bacteria growth and production analysis on single cell levelPUB
Grünberger A, Probst C, Wiechert W, Kohlheyer D (2013)
Presented at the 2nd International Conference Implementation of Microreactor Technology in Biotechnology, Cavtat, Croatia. -
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912621Towards High-Throughput Microbial Single Cell Analysis In Picoliter BioreactorsPUB
Grünberger A, Mustafi N, Probst C, Frunzke J, Wiechert W, Kohlheyer D (2013)
Presented at the 9th European Congress of Chemical Engineering, Den Haag, The Netherlands. -
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912626Femtoliter chemostat for long-term bacteria growth and production analysis on single cell levelPUB
Grünberger A, Probst C, Wiechert W, Kohlheyer D (2013)
Presented at the Single Cell Analysis Europe 2013, Barcelona, Spain. -
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912809Microbial Metabolite Production – Live in ConcertPUB
Frunzke J, Mahr R, Grünberger A, Mustafi N, Kohlheyer D (2013)
Presented at the Advanced Imaging in Cell- and Microbiology: Technology and Applications (AICMB), Jülich, Germany. -
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912828Continuous Non-Invasive Real-Time Viability Measurement of Bacteria on Single Cell Level in Microfluidic Chip Cultures?PUB
Krämer C, Grünberger A, Probst C, Wiechert W, Kohlheyer D (2013)
Presented at the Advanced Imaging in Cell- and Microbiology: Technology and Applications (AICMB), Jülich, Germany. -
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912830Microfluidic single-cell analysis in dynamic environmentsPUB
Probst C, Grünberger A, Krämer C, Wiechert W, Kohlheyer D (2013)
Presented at the Advanced Imaging in Cell- and Microbiology: Technology and Applications (AICMB), Jülich, Germany. -
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912835Application of a genetically- encoded metabolite sensor for single cell analysis and the development of production strainsPUB
Mahr R, Mustafi N, Grünberger A, Helfrich S, Nöh K, Kohlheyer D, Frunzke J (2013)
Presented at the Advanced Imaging in Cell- and Microbiology: Technology and Applications (AICMB), Jülich, Germany. -
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912826Exploration and Analysis of cell population development. Customizable interactive lineage treesPUB
Helfrich S, Azzouzi CE, Grünberger A, Wiechert W, Nöh K (2013)
Presented at the Jülich Biotech Day, Jülich, Germany. -
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912833Single-cell dynamics of the SOS response in Corynebacterium glutamicumPUB
Nanda AM, Heyer A, Grünberger A, Helfrich S, Kohlheyer D, Nöh K, Frunzke J (2013)
Presented at the Advanced Imaging in Cell- and Microbiology: Technology and Applications (AICMB), Jülich, Germany. -
2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912600Microfluidic growth chambers with optical tweezers for full spatial single-cell control and analysis of evolving microbesPUB | DOI | WoS | PubMed | Europe PMC
Probst C, Grünberger A, Wiechert W, Kohlheyer D (2013)
Journal of microbiological methods 95(3): 470-476. -
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912612SOS-induced spontaneous prophage induction in Corynebacterium glutamicumPUB
Nanda A, Heyer A, Krämer C, Grünberger A, Kohlheyer D, Frunzke J (2013)
Presented at the EMBL Heidelberg "New Approaches and Concepts in Microbiology", Heidelberg, Germany. -
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912617Continuous viability fluorescent staining of growing Corynebacterium glutamicum colonies without sample preparation in an automated microfluidic measurement systemPUB
Krämer C, Grünberger A, Probst C, Wiechert W, Kohlheyer D (2013)
Presented at the How Deas Is Dead III Conference, Berlin, Germany. -
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912624High-throughput Microbial Single Cell analysis in Picoliter BioreactorsPUB
Grünberger A, Mustafi N, Probst C, Frunzke J, Wiechert W, Kohlheyer D (2013)
Presented at the VAAM-Tagung 2013, Bremen, Germany. -
2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912631Beyond growth rate 0.6: Corynebacterium glutamicum cultivated in highly diluted environmentsPUB | DOI | WoS | PubMed | Europe PMC
Grünberger A, van Ooyen J, Paczia N, Rohe P, Schendzielorz G, Eggeling L, Wiechert W, Kohlheyer D, Noack S (2013)
Biotechnology and bioengineering 110(1): 220-228. -
2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912747Synthesis of Chiral Cyanohydrins by Recombinant Escherichia coli Cells in a Micro-Aqueous Reaction SystemPUB | DOI | WoS | PubMed | Europe PMC
Scholz KE, Okrob D, Kopka B, Grünberger A, Pohl M, Jaeger K-E, Krauss U (2012)
Applied and Environmental Microbiology 78(14): 5025-5027. -
2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912635Metabolite sensors for single-cell isolation of producing bacteriaPUB
Binder S, Schendzielorz G, Kohlheyer D, Grünberger A, Wiechert W, Bott M, Eggeling L (2012)
Presented at the Metabolic Engineering IX, Biarritz, France. -
2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912642Single Cell Microfluidics: From Fabrication to ApplicationPUB
Grünberger A, Frank P, Probst C, Wiechert W, Kohlheyer D (2012)
Presented at the Jülich Biotech Day, Jülich, Germany. -
2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912647Semi-Automated Evaluation of Microbial Observables from High-Throughput Time-lapse MicroscopyPUB
Helfrich S, Grünberger A, Kohlheyer D, Wiechert W, Nöh K (2012)
Presented at the German Conference on Bioinformatics 2012, Jena (Germany). -
2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912767Fermentation at Picoliter Scale: Microfluidics for single cell analysis of prokaryotic production strainsPUB
Grünberger A, Probst C, Wiechert W, Kohlheyer D (2012)
Presented at the Achema 2012, Frankfurt, Germany. -
2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912837Screening of Escherichia coli on single-cell level by hyphenating microfluidic picoliter fermentation and optical tweezersPUB
Probst C, Grünberger A, Wiechert W, Kohlheyer D (2012)
Presented at the 3rd European Conference on Microfluidics, Heidelberg, Germany. -
2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912728
A disposable picolitre bioreactor for cultivation and investigation of industrially relevant bacteria on the single cell levelPUB | PDF | DOI | WoS | PubMed | Europe PMC
Grünberger A, Paczia N, Probst C, Schendzielorz G, Eggeling L, Noack S, Wiechert W, Kohlheyer D (2012)
Lab on a Chip 12(11): 2060-2068. -
2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912776Single Cell Analysis of Industrially Relevant Bacterial Strains in Picoliter EnvironmentsPUB
Grünberger A, Probst. C, Frank P, Wiechert W, Kohlheyer D (2012)
Presented at the EMBL Conference – Microfluidics 2012, Heidelberg, Germany. -
2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912839Phenotypic Sorting and Analysis of Bacteria Production Strains using Optical Tweezers and MicrofluidicsPUB
Probst C, Grünberger A, Wiechert W, Kohlheyer D (2012)
Presented at the EMBL Conference – Microfluidics 2012, Heidelberg, Germany. -
2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912841Dynamics of the SOS response in single cells of Corynebacterium glutamicumPUB
Nanda AM, Grünberger A, Heyer A, Helfrich S, Kohlheyer D, Nöh K, Frunzke J (2012)
Presented at the 2nd Molecular Microbiology Meeting Würzburg, Würzburg, Germany. -
2012 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2912639Phenotypic Sorting and Analysis of Bacteria ProductionStrains Using Optical Tweezers and MicrofluidicsPUB | DOI
Probst C, Grünberger A, Kohlheyer D, Wiechert W (2012)
Chemie - Ingenieur - Technik: CIT 84(8): 1344. -
2012 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2912641Femtoliter Growth Channels. Bacteria Long-Term Growth Patterns Analysis on Singel Cell LevelPUB | DOI
Grünberger A, Probst C, Wiechert W, Kohlheyer D (2012)
Chemie - Ingenieur - Technik (CIT) 84(8): 1407. -
2012 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2912646Industrial Biotechnology meets Microfluidics - Disposable high-throughput single cell analysis device for industrially relevant bacterial strainsPUB
Grünberger A, Helfrich S, Probst C, Nöh K, Wiechert W, Kohlheyer D (2012)
In: Proceedings - µFLU-12. Colin S (Ed); Publications S.H.F. Paris: SHF. -
2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912633Picoliter bioreactors for growth heterogeneity studies of industrially relevant bacteria on single cell levelPUB
Grünberger A, Probst C, Wiechert W, Kohlheyer D (2012)
Presented at the 2nd BioProScale Symposium: Inhomogeneities in large-scale bioprocesses: System biology and process dynamics, Berlin, Germany. -
2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912638A biosensor for the intracellular detection of L-methionine and branched-chain amino acids - Monitoring of amino acid production at the single cell levelPUB
Mustafi N, Grünberger A, Helfrich S, Kohlheyer D, Nöh K, Bott M, Frunzke J (2012)
Presented at the 15th International Conference on Biotechnology, Istanbul, Turkey. -
2012 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2912640High-Throughput Growth Rate Determination of Bacteria Micro colonies on Single Cell LevelPUB | DOI
Grünberger A, Probst C, Wiechert W, Kohlheyer D (2012)
Chemie - Ingenieur - Technik: CIT 84(8): 1336-1337. -
2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912645Catch it and batch it: picoliter fermentation at the single cell levelPUB
Kohlheyer D, Grünberger A, Probst C, Frank P, Wiechert W (2012)
Presented at the International Workshop on New and Synthetic Bioproduction Systems, Hamburg-Harburg, Germany. -
2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912746The development and application of a single-cell biosensor for the detection of l-methionine and branched-chain amino acidsPUB | DOI | WoS | PubMed | Europe PMC
Mustafi N, Grünberger A, Kohlheyer D, Bott M, Frunzke J (2012)
Metabolic Engineering 14(4): 449-457. -
2012 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2912758Single Cell Trapping and Analysis for Prokaryotic Production Strains in Sub-µm Fluidic StructuresPUB
Grünberger A, Probst C, Binder S, Ziaee R, Eggeling L, Wiechert W, Kohlheyer D (2012)
In: 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011 (MiroTAS 2011). Landers J (Ed); Red Hook, NY: Curran. -
2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912777Towards high-throughput single cell growth optimization and production analysis using picoliter bioreactorsPUB
Grünberger A, Probst C, Wiechert W, Kohlheyer D (2012)
Presented at the Metabolic Engineering IX 2012, Biarritz, France. -
2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912838“Catch it and Batch it”- Microfluidics single cell batch cultivation utilizing picoliter bioreactorsPUB
Frank P, Probst C, Grünberger A, Wiechert W, Kohlheyer D (2012)
Presented at the ProcessNet- Jahrestagung 2012 und 30. DECHEMA Jahrestagung der Biotechnologen, Karlsruhe, Germany. -
2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912840Dynamics of the SOS response in single cells of Corynebacterium glutamicumPUB
Nanda AM, Grünberger A, Heyer A, Helfrich S, Kohlheyer D, Nöh K, Frunzke J (2012)
Presented at the Microbial Stress: from Molecules to System, Belgirate (VB)/Maggiore Lake, Italy. -
2012 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2912643High-Throughput lineage tree investigations of bacteria microcolonies using arrays of monolayer growth chambersPUB
Grünberger A, Helfrich S, Probst C, Wiechert W, Nöh K, Kohlheyer D (2012)
In: Proceedings of The Sixteenth International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS 2012). San Diego, California: CBMS. -
2011 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912778Single Cell Trapping and Analysis for Prokaryotic Production Strains in Sub -µm Fluidic StructuresPUB
Grünberger A, Probst C, Wiechert W, Kohlheyer D (2011)
Presented at the NanoBioTech-Montreux 2011, Montreux, Switzerland. -
2011 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912843Fluorescence reporters for the analysis of whole cell biocatalysts in non-conventional mediaPUB
Scholz KE, Okrob D, Kopka B, Grünberger A, Pohl M, Jaeger KE, Krauss U (2011)
Presented at the Biotrans 2011, Giardini Naxos (Messina), Italy. -
2011 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912811Sub-µm Fluidic Structures for Single Cell Trapping and Analysis of Prokaryotic Production StrainsPUB
Kohlheyer D, Grünberger A, Probst C, Wiechert W (2011)
Presented at the 21st Annual conference of the German Society for Cytometry, Bonn, Germany. -
2011 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912842A biosensor for the intracellular detection of L-methionine and branched-chain amino acidsPUB
Mustafi N, Grünberger A, Kohlheyer D, Bott M, Frunzke J (2011)
Presented at the 5th International Conference on Analysis of Microbial Cells at the Single Cell Level, Caryy-Le-Rouet, France. -
2011 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912768A continuous picoliter bioreactor for heterogeneity studies of bacteria microcoloniesPUB
Grünberger A, Probst C, Wiechert W, Kohlheyer D (2011)
Presented at the NanoBioTech-Montreux 2011, Montreux, Switzerland. -
2010 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912812Protein Interactions from Kirwood-Buff Analysis of Light Scattering and Coarse-Grained Molecular ModelsPUB
Blanko MA, Grünberger A, Sahin E, Roberts CJ (2010)
Presented at the AIChE Annual Meeting, Salt Lake City (UT), USA. -
2009 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912813Media optimization for the microalgae Chamydomonas reinhardtii Stm6 using statistical designPUB
Grünberger A, Stephens E, Hankamer B (2009)
Presented at the IMB Summer Symposium: A systems Biology approach to biofuel production: From light capture to biodiesel production, Brisbane, Australia.