Vizardous: interactive analysis of microbial populations with single cell resolution
Helfrich S, Azzouzi CE, Probst C, Seiffarth J, Grünberger A, Wiechert W, Kohlheyer D, Nöh K (2015)
Bioinformatics 31(23): 3875-3877: btv468.
Zeitschriftenaufsatz
| Veröffentlicht | Englisch
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Autor*in
Helfrich, Stefan;
Azzouzi, Charaf E.;
Probst, Christopher;
Seiffarth, Johannes;
Grünberger, AlexanderUniBi;
Wiechert, Wolfgang;
Kohlheyer, Dietrich;
Nöh, Katharina
Abstract / Bemerkung
Motivation: Single cell time-lapse microscopy is a powerful method for investigating heterogeneous cell behavior. Advances in microfluidic lab-on-a-chip technologies and live-cell imaging render the parallel observation of the development of individual cells in hundreds of populations possible. While image analysis tools are available for cell detection and tracking, biologists are still confronted with the challenge of exploring and evaluating this data.
Results: We present the software tool Vizardous that assists scientists with explorative analysis and interpretation tasks of single cell data in an interactive, configurable and visual way. With Vizardous, lineage tree drawings can be augmented with various, time-resolved cellular characteristics. Associated statistical moments bridge the gap between single cell and the population-average level.
Availability and implementation: The software, including documentation and examples, is available as executable Java archive as well as in source form at https://github.com/modsim/vizardous.
Contact:k.noeh@fz-juelich.de
Supplementary information:Supplementary data are available at Bioinformatics online.
Erscheinungsjahr
2015
Zeitschriftentitel
Bioinformatics
Band
31
Ausgabe
23
Art.-Nr.
btv468
Seite(n)
3875-3877
ISSN
1367-4803
eISSN
1460-2059
Page URI
https://pub.uni-bielefeld.de/record/2912555
Zitieren
Helfrich S, Azzouzi CE, Probst C, et al. Vizardous: interactive analysis of microbial populations with single cell resolution. Bioinformatics. 2015;31(23):3875-3877: btv468.
Helfrich, S., Azzouzi, C. E., Probst, C., Seiffarth, J., Grünberger, A., Wiechert, W., Kohlheyer, D., et al. (2015). Vizardous: interactive analysis of microbial populations with single cell resolution. Bioinformatics, 31(23), 3875-3877., btv468. doi:10.1093/bioinformatics/btv468
Helfrich, Stefan, Azzouzi, Charaf E., Probst, Christopher, Seiffarth, Johannes, Grünberger, Alexander, Wiechert, Wolfgang, Kohlheyer, Dietrich, and Nöh, Katharina. 2015. “Vizardous: interactive analysis of microbial populations with single cell resolution”. Bioinformatics 31 (23): 3875-3877: btv468.
Helfrich, S., Azzouzi, C. E., Probst, C., Seiffarth, J., Grünberger, A., Wiechert, W., Kohlheyer, D., and Nöh, K. (2015). Vizardous: interactive analysis of microbial populations with single cell resolution. Bioinformatics 31, 3875-3877:btv468.
Helfrich, S., et al., 2015. Vizardous: interactive analysis of microbial populations with single cell resolution. Bioinformatics, 31(23), p 3875-3877: btv468.
S. Helfrich, et al., “Vizardous: interactive analysis of microbial populations with single cell resolution”, Bioinformatics, vol. 31, 2015, pp. 3875-3877, : btv468.
Helfrich, S., Azzouzi, C.E., Probst, C., Seiffarth, J., Grünberger, A., Wiechert, W., Kohlheyer, D., Nöh, K.: Vizardous: interactive analysis of microbial populations with single cell resolution. Bioinformatics. 31, 3875-3877 : btv468 (2015).
Helfrich, Stefan, Azzouzi, Charaf E., Probst, Christopher, Seiffarth, Johannes, Grünberger, Alexander, Wiechert, Wolfgang, Kohlheyer, Dietrich, and Nöh, Katharina. “Vizardous: interactive analysis of microbial populations with single cell resolution”. Bioinformatics 31.23 (2015): 3875-3877: btv468.
Daten bereitgestellt von European Bioinformatics Institute (EBI)
6 Zitationen in Europe PMC
Daten bereitgestellt von Europe PubMed Central.
Coarse-graining bacteria colonies for modelling critical solute distributions in picolitre bioreactors for bacterial studies on single-cell level.
Westerwalbesloh C, Grünberger A, Wiechert W, Kohlheyer D, von Lieres E., Microb Biotechnol 10(4), 2017
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Westerwalbesloh C, Grünberger A, Wiechert W, Kohlheyer D, von Lieres E., Microb Biotechnol 10(4), 2017
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