107 Publikationen
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2024 | Preprint | Veröffentlicht | PUB-ID: 2993878Belmann, P., Osterholz, B., Kleinboelting, N., Pühler, A., Schlüter, A., & Sczyrba, A. (2024). Metagenomics-Toolkit: The Flexible and Efficient Cloud-Based Metagenomics Workflow featuring Machine Learning-Enabled Resource Allocation. bioRxiv. https://doi.org/10.1101/2024.10.22.619569
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2024 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2985402Heyer, R., Hellwig, P., Maus, I., Walke, D., Schlüter, A., Hassa, J., Sczyrba, A., et al. (2024). Breakdown of hardly degradable carbohydrates (lignocellulose) in a two-stage anaerobic digestion plant is favored in the main fermenter. Water Research, 250, 121020. https://doi.org/10.1016/j.watres.2023.121020
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2023 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2977923Nelkner, J., Huang, L., Lin, T. W., Schulz, A., Osterholz, B., Henke, C., Blom, J., et al. (2023). Abundance, classification and genetic potential of Thaumarchaeota in metagenomes of European agricultural soils: a meta-analysis. Environmental Microbiome, 18(1), 26. https://doi.org/10.1186/s40793-023-00479-9
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2023 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2983209Hassa, J., Tubbesing, T. J., Maus, I., Heyer, R., Benndorf, D., Effenberger, M., Henke, C., et al. (2023). Uncovering Microbiome Adaptations in a Full-Scale Biogas Plant: Insights from MAG-Centric Metagenomics and Metaproteomics. Microorganisms, 11(10), 2412. https://doi.org/10.3390/microorganisms11102412
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2023 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984553Schimmler, S., Altenhöner, R., Bernard, L., Fluck, J., Klinger, A., Lorenz, S., Mathiak, B., et al. (2023). Base4NFDI - Basic Services for NFDI. Proceedings of the Conference on Research Data Infrastructure, 1. https://doi.org/10.52825/cordi.v1i.336
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2023 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984552Hoffmann, N., Maus, I., Beier, S., Belmann, P., Krüger, J., Tauch, A., Goesmann, A., et al. (2023). Embedding the de.NBI Cloud in the National Research Data Infrastructure Activities. Proceedings of the Conference on Research Data Infrastructure, 1. https://doi.org/10.52825/cordi.v1i.387
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2023 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984551Förstner, K. U., Becker, A., Blom, J., Bork, P., Clavel, T., Dieckmann, M., Goesmann, A., et al. (2023). NFDI4Microbiota – national research data infrastructure for microbiota research. Research Ideas and Outcomes, 9. https://doi.org/10.3897/rio.9.e110501
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2023 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2979860Wolf, M., Schallert, K., Knipper, L., Sickmann, A., Sczyrba, A., Benndorf, D., & Heyer, R. (2023). Advances in the clinical use of metaproteomics. Expert review of proteomics. https://doi.org/10.1080/14789450.2023.2215440
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2023 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2968667Olo Ndela, E., Roux, S., Henke, C., Sczyrba, A., Sime Ngando, T., Varsani, A., & Enault, F. (2023). Reekeekee- and roodoodooviruses, two different Microviridae clades constituted by the smallest DNA phages. Virus Evolution , 9(1), veac123. https://doi.org/10.1093/ve/veac123
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2022 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2969509Neri, U., Wolf, Y. I., Roux, S., Camargo, A. P., Lee, B., Kazlauskas, D., Chen, I. M., et al. (2022). Expansion of the global RNA virome reveals diverse clades of bacteriophages. Cell, 185(21), 4023-4037.e18. https://doi.org/10.1016/j.cell.2022.08.023
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2022 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2969511Fremin, B. J., Bhatt, A. S., Kyrpides, N. C., Sengupta, A., Sczyrba, A., Maria da Silva, A., Buchan, A., et al. (2022). Thousands of small, novel genes predicted in global phage genomes. Cell Reports, 39(12), 110984. https://doi.org/10.1016/j.celrep.2022.110984
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2022 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2967098Khesali Aghtaei, H., Püttker, S., Maus, I., Heyer, R., Huang, L., Sczyrba, A., Reichl, U., et al. (2022). Adaptation of a microbial community to demand-oriented biological methanation. Biotechnology for Biofuels and Bioproducts, 15(1), 125. https://doi.org/10.1186/s13068-022-02207-w
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2022 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2966901Maus, I., Wibberg, D., Belmann, P., Hahnke, S., Huang, L., Spröer, C., Bunk, B., et al. (2022). The novel oligopeptide utilizing species Anaeropeptidivorans aminofermentans M3/9T, its role in anaerobic digestion and occurrence as deduced from large-scale fragment recruitment analyses. Frontiers in Microbiology, 13, 1032515. https://doi.org/10.3389/fmicb.2022.1032515
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2022 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2966286Joshi, A., Young, D., Huang, L., Mosberger, L., Munk, B., Vinzelj, J., Flad, V., et al. (2022). Effect of Growth Media on the Diversity of Neocallimastigomycetes from Non-Rumen Habitats. Microorganisms, 10(10), 1972. https://doi.org/10.3390/microorganisms10101972
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2022 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2965465Young, D., Joshi, A., Huang, L., Munk, B., Wurzbacher, C., Youssef, N. H., Elshahed, M. S., et al. (2022). Simultaneous Metabarcoding and Quantification of Neocallimastigomycetes from Environmental Samples: Insights into Community Composition and Novel Lineages. Microorganisms, 10(9), 1749. https://doi.org/10.3390/microorganisms10091749
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2022 | Herausgeber*in Sammelwerk | Veröffentlicht | PUB-ID: 2963745Sczyrba A., & German Network for Bioinformatics Infrastructure (de.NBI) (Eds.) (2022). Development and Operation of the Federated de.NBI Cloud: Contributions of the German Network for Bioinformatics Infrastructure. Bielefeld: Center for Biotechnology, de.NBI Administration Office. https://doi.org/10.4119/unibi/2963745
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2022 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2962388Meyer, F., Fritz, A., Deng, Z. - L., Koslicki, D., Lesker, T. R., Gurevich, A., Robertson, G., et al. (2022). Critical Assessment of Metagenome Interpretation: the second round of challenges. Nature Methods, 19, 429-440. https://doi.org/10.1038/s41592-022-01431-4
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2021 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2950292Blifernez-Klassen, O., Klassen, V., Wibberg, D., Cebeci, E., Henke, C., Rückert, C., Chaudhari, S., et al. (2021). Phytoplankton consortia as a blueprint for mutually beneficial eukaryote-bacteria ecosystems based on the biocoenosis of Botryococcus consortia. Scientific Reports, 11(1), 1726. https://doi.org/10.1038/s41598-021-81082-1
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2021 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2957501Brandt, D., Simunovic, M., Busche, T., Haak, M., Belmann, P., Jünemann, S., Schulz, T., et al. (2021). Multiple Occurrences of a 168-Nucleotide Deletion in SARS-CoV-2 ORF8, Unnoticed by Standard Amplicon Sequencing and Variant Calling Pipelines. Viruses, 13(9), 1870. https://doi.org/10.3390/v13091870
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2021 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2956369Fritz, A., Bremges, A., Deng, Z. - L., Lesker, T. R., Götting, J., Ganzenmueller, T., Sczyrba, A., et al. (2021). Haploflow: strain-resolved de novo assembly of viral genomes. Genome Biology, 22(1), 212. https://doi.org/10.1186/s13059-021-02426-8
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2021 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2960171Van Den Bossche, T., Kunath, B. J., Schallert, K., Schäpe, S. S., Abraham, P. E., Armengaud, J., Arntzen, M. Ø., et al. (2021). Critical Assessment of MetaProteome Investigation (CAMPI): a multi-laboratory comparison of established workflows. Nature Communications, 12(1), 7305. https://doi.org/10.1038/s41467-021-27542-8
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2021 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 2960900Leitner, F., Carazo, J. M., Bischof, J., Haley, N., Audergon, P., Sorzano, C. O., del Cano, L., et al. (2021). EOSC-Life Report on the work of the initial demonstrators. Presented at the . https://doi.org/10.5281/zenodo.4817723
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2021 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2955512Aevarsson, A., Kaczorowska, A. - K., Adalsteinsson, B. T., Ahlqvist, J., Al-Karadaghi, S., Altenbuchner, J., Arsin, H., et al. (2021). Going to extremes - a metagenomic journey into the dark matter of life. FEMS microbiology letters, fnab067. https://doi.org/10.1093/femsle/fnab067
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2021 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2952275Meyer, F., Lesker, T. - R., Koslicki, D., Fritz, A., Gurevich, A., Darling, A. E., Sczyrba, A., et al. (2021). Tutorial: assessing metagenomics software with the CAMI benchmarking toolkit. Nature Protocols, 16(4), 1785–1801. https://doi.org/10.1038/s41596-020-00480-3
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2021 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2951537Tabacchioni, S., Passato, S., Ambrosino, P., Huang, L., Caldara, M., Cantale, C., Hett, J., et al. (2021). Identification of Beneficial Microbial Consortia and Bioactive Compounds with Potential as Plant Biostimulants for a Sustainable Agriculture. Microorganisms, 9(2), 426. https://doi.org/10.3390/microorganisms9020426
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2020 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2941645Maus, I., Klocke, M., Derenkó, J., Stolze, Y., Beckstette, M., Jost, C., Wibberg, D., et al. (2020). Impact of process temperature and organic loading rate on cellulolytic / hydrolytic biofilm microbiomes during biomethanation of ryegrass silage revealed by genome-centered metagenomics and metatranscriptomics. Environmental Microbiome, 15(1), 7. https://doi.org/10.1186/s40793-020-00354-x
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2020 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953267Schulte-Schrepping, J., Reusch, N., Paclik, D., Baßler, K., Schlickeiser, S., Zhang, B., Krämer, B., et al. (2020). Severe COVID-19 Is Marked by a Dysregulated Myeloid Cell Compartment. Cell, 182(6), 1419-1440.e23. https://doi.org/10.1016/j.cell.2020.08.001
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2020 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2944226Rettenmaier, R., Schneider, M., Munk, B., Lebuhn, M., Jünemann, S., Sczyrba, A., Maus, I., et al. (2020). Importance of Defluviitalea raffinosedens for Hydrolytic Biomass Degradation in Co-Culture with Hungateiclostridium thermocellum. Microorganisms, 8(6), 915. https://doi.org/10.3390/microorganisms8060915
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2020 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2949597Maus, I., Tubbesing, T. J., Wibberg, D., Heyer, R., Hassa, J., Tomazetto, G., Huang, L., et al. (2020). The Role of Petrimonas mucosa ING2-E5AT in Mesophilic Biogas Reactor Systems as Deduced from Multiomics Analyses. Microorganisms, 8(12), 2024. doi:10.3390/microorganisms8122024
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2020 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2948401Moore, M., Wesemann, C., Gossmann, N., Sahm, A., Krüger, J., Sczyrba, A., & Dietz, K. - J. (2020). ConCysFind: a pipeline tool to predict conserved amino acids of protein sequences across the plant kingdom. BMC Bioinformatics, 21(1), 490. doi:10.1186/s12859-020-03749-2
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2020 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2941704Lesker, T. R., Durairaj, A. C., Galvez, E. J. C., Lagkouvardos, I., Baines, J. F., Clavel, T., Sczyrba, A., et al. (2020). An Integrated Metagenome Catalog Reveals New Insights into the Murine Gut Microbiome. Cell reports, 30(9), 2909-2922.e6. doi:10.1016/j.celrep.2020.02.036
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2019 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2935923Nelkner, J., Henke, C., Lin, T. W., Pätzold, W., Hassa, J., Jaenicke, S., Grosch, R., et al. (2019). Effect of Long-Term Farming Practices on Agricultural Soil Microbiome Members Represented by Metagenomically Assembled Genomes (MAGs) and Their Predicted Plant-Beneficial Genes. Genes, 10(6), 424. https://doi.org/10.3390/genes10060424
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2019 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2933767Fritz, A., Hofmann, P., Majda, S., Dahms, E., Dröge, J., Fiedler, J., Lesker, T. R., et al. (2019). CAMISIM: simulating metagenomes and microbial communities. Microbiome, 7(1), 17. https://doi.org/10.1186/s40168-019-0633-6
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2019 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2934798Pankoke, H., Maus, I., Loh, G., Huser, A., Seifert, J., Tilker, A., Hark, S., et al. (2019). Evaluation of commercially available DNA extraction kits for the analysis of the broiler chicken cecal microbiota. FEMS microbiology letters. https://doi.org/10.1093/femsle/fnz033
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2019 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2936223Belmann, P., Fischer, B., Krüger, J., Procházka, M., Rasche, H., Prinz, M., Hanussek, M., et al. (2019). de.NBI Cloud federation through ELIXIR AAI. F1000Research, 8, 842. doi:10.12688/f1000research.19013.1
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2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2930593Linden, M., Prochazka, M., Lappalainen, I., Bucik, D., Vyskocil, P., Kuba, M., Silén, S., et al. (2018). Common ELIXIR Service for Researcher Authentication and Authorisation. F1000Research, 7, 1199. https://doi.org/10.12688/f1000research.15161.1
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2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2920723Meyer, F., Hofmann, P., Belmann, P., Garrido-Oter, R., Fritz, A., Sczyrba, A., & McHardy, A. C. (2018). AMBER: Assessment of Metagenome BinnERs. GigaScience, 7(6), giy069. https://doi.org/10.1093/gigascience/giy069
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2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2920777Celis, J. S., Wibberg, D., Ramírez-Portilla, C., Rupp, O., Sczyrba, A., Winkler, A., Kalinowski, J., et al. (2018). Binning Enables Efficient Host Genome Reconstruction in Cnidarian Holobionts. GigaScience, 7(7), giy075. doi:10.1093/gigascience/giy075
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2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2920750Maus, I., Rumming, M., Bergmann, I., Heeg, K., Pohl, M., Nettmann, E., Jaenicke, S., et al. (2018). Characterization of Bathyarchaeota genomes assembled from metagenomes of biofilms residing in mesophilic and thermophilic biogas reactors. Biotechnology for Biofuels, 11(1), 167. doi:10.1186/s13068-018-1162-4
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2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2915890Huang, L., Krüger, J., & Sczyrba, A. (2018). Analyzing large scale genomic data on the cloud with Sparkhit. Bioinformatics, 34(9), 1457-1465. doi:10.1093/bioinformatics/btx808
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2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2916929Stolze, Y., Bremges, A., Maus, I., Pühler, A., Sczyrba, A., & Schlüter, A. (2018). Targeted in situ metatranscriptomics for selected taxa from mesophilic and thermophilic biogas plants. Microbial Biotechnology, 11(4), 667-679. doi:10.1111/1751-7915.12982
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2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2914959da Schoren Costa, P., Bolzan de Campos, S., Albersmeier, A., Dirksen, P., Pereira Dresseno, A. L., Andrade Pais dos Santos, O. J., Lima Milani, K. M., et al. (2018). Invasion ecology applied to inoculation of plant growth promoting bacteria through a novel SIMPER-PCA approach. Plant and Soil, 422(1-2), 467-478. doi:10.1007/s11104-017-3492-6
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2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2918275Fleming, E. J., Woyke, T., Donatello, A. R., Kuypers, M. M. M., Sczyrba, A., Littmann, S., & Emerson, D. (2018). Insights into the fundamental physiology of the uncultured Fe-oxidizing bacterium Leptothrix ochracea. Applied and Environmental Microbiology, 84(9), e02239-17. doi:10.1128/aem.02239-17
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2017 | Zeitschriftenaufsatz | PUB-ID: 2913876Sczyrba, A., Hofman, P., Belmann, P., Koslicki, D., Janssen, S., Dröge, J., Gregor, I., et al. (2017). Benchmark data sets, software results and reference data for the first CAMI challenge. GigaScience Database. https://doi.org/10.5524/100344
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2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2914367Sczyrba, A., Hofmann, P., Belmann, P., Koslicki, D., Janssen, S., Dröge, J., Gregor, I., et al. (2017). Critical Assessment of Metagenome Interpretation—a benchmark of metagenomics software. Nature Methods, 14(11), 1063-1071. https://doi.org/10.1038/nmeth.4458
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2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2909153Yu, J., Blom, J., Sczyrba, A., & Goesmann, A. (2017). Rapid protein alignment in the cloud: HAMOND combines fast DIAMOND alignments with Hadoop parallelism. Journal of Biotechnology, 257, 58-60. https://doi.org/10.1016/j.jbiotec.2017.02.020
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2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2915516Maus, I., Bremges, A., Stolze, Y., Hahnke, S., Cibis, K. G., Koeck, D. E., Kim, Y. S., et al. (2017). Genomics and prevalence of bacterial and archaeal isolates from biogas-producing microbiomes. Biotechnology for Biofuels, 10(1), 264. doi:10.1186/s13068-017-0947-1
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2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2913556Jünemann, S., Kleinbölting, N., Jaenicke, S., Henke, C., Hassa, J., Nelkner, J., Stolze, Y., et al. (2017). Bioinformatics for NGS-based metagenomics and the application to biogas research. Journal of Biotechnology, 261(SI), 10-23. doi:10.1016/j.jbiotec.2017.08.012
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2017 | Datenpublikation | PUB-ID: 2914921Huang, L., Krüger, J., & Sczyrba, A. (2017). Sparkhit evaluation data set. Bielefeld University. doi:10.4119/unibi/2914921
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2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2904836Heyer, R., Benndorf, D., Kohrs, F., De Vrieze, J., Boon, N., Hoffmann, M., Rapp, E., et al. (2016). Proteotyping of biogas plant microbiomes separates biogas plants according to process temperature and reactor type. Biotechnology for Biofuels, 9(1), 155. doi:10.1186/s13068-016-0572-4
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2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2905260Maus, I., Koeck, D. E., Cibis, K. G., Hahnke, S., Kim, Y. S., Langer, T., Kreubel, J., et al. (2016). Unraveling the microbiome of a thermophilic biogas plant by metagenome and metatranscriptome analysis complemented by characterization of bacterial and archaeal isolates. Biotechnology for Biofuels, 9(1), 171. doi:10.1186/s13068-016-0581-3
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2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2901729Bremges, A., Singer, E., Woyke, T., & Sczyrba, A. (2016). MeCorS: Metagenome-enabled error correction of single cell sequencing reads. Bioinformatics, 32(14), 2199-2201. doi:10.1093/bioinformatics/btw144
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2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2900928Nesme, J., Achouak, W., Agathos, S., Bailey, M., Baldrian, P., Brunel, D., Frostegard, A., et al. (2016). Back to the future of soil metagenomics. Frontiers in Microbiology, 7, 73. doi:10.3389/fmicb.2016.00073
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2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2904815Stolze, Y., Bremges, A., Rumming, M., Henke, C., Maus, I., Pühler, A., Sczyrba, A., et al. (2016). Identification and genome reconstruction of abundant distinct taxa in microbiomes from one thermophilic and three mesophilic production-scale biogas plants. Biotechnology for Biofuels, 9(1), 156. doi:10.1186/s13068-016-0565-3
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2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2907633Lux, M., Krüger, J., Rinke, C., Maus, I., Schlüter, A., Woyke, T., Sczyrba, A., et al. (2016). acdc – Automated Contamination Detection and Confidence estimation for single-cell genome data. BMC Bioinformatics, 17(1), 543. doi:10.1186/s12859-016-1397-7
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2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2903489Maus, I., Cibis, K. G., Bremges, A., Stolze, Y., Wibberg, D., Tomazetto, G., Blom, J., et al. (2016). Genomic characterization of Defluviitoga tunisiensis L3, a key hydrolytic bacterium in a thermophilic biogas plant and its abundance as determined by metagenome fragment recruitment. Journal of Biotechnology, 232, 50-60. doi:10.1016/j.jbiotec.2016.05.001
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2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2903302Wibberg, D., Bremges, A., Dammann-Kalinowski, T., Maus, I., Igeño, M. I., Vogelsang, R., König, C., et al. (2016). Finished genome sequence and methylome of the cyanide-degrading Pseudomonas pseudoalcaligenes strain CECT5344 as resolved by single-molecule real-time sequencing. Journal of Biotechnology, 232, 61-68. doi:10.1016/j.jbiotec.2016.04.008
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2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2901418Campos, S. B., Lisboa, B. B., Camargo, F. A. O., Bayer, C., Sczyrba, A., Dirksen, P., Albersmeier, A., et al. (2016). Soil suppressiveness and its relations with the microbial community in a Brazilian subtropical agroecosystem under different management systems. Soil Biology and Biochemistry, 96, 191-197. doi:10.1016/j.soilbio.2016.02.010
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2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2902190Stiefel, F., Fischer, S., Sczyrba, A., Otte, K., & Hesse, F. (2016). miRNA profiling of high, low and non-producing CHO cells during biphasic fed-batch cultivation reveals process relevant targets for host cell engineering. Journal of Biotechnology, 225, 31-43. doi:10.1016/j.jbiotec.2016.03.028
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2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2901675Krahn, T., Wibberg, D., Maus, I., Winkler, A., Bontron, S., Sczyrba, A., Nordmann, P., et al. (2016). Intraspecies transfer of the chromosomally encoded Acinetobacter baumannii blaNDM-1 carbapenemase gene. Antimicrobial Agents and Chemotherapy, 60(5), 3032-3040. doi:10.1128/AAC.00124-16
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2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2904234Ortseifen, V., Stolze, Y., Maus, I., Sczyrba, A., Bremges, A., Albaum, S., Jaenicke, S., et al. (2016). An integrated metagenome and -proteome analysis of the microbial community residing in a biogas production plant. Journal of Biotechnology, 231, 268-279. doi:10.1016/j.jbiotec.2016.06.014
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2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2764906Bremges, A., Maus, I., Belmann, P., Eikmeyer, F. G., Winkler, A., Albersmeier, A., Pühler, A., et al. (2015). Deeply sequenced metagenome and metatranscriptome of a biogas-producing microbial community from an agricultural production-scale biogas plant. GigaScience, 4(1), 33. https://doi.org/10.1186/s13742-015-0073-6
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2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2782501Belmann, P., Dröge, J., Bremges, A., McHardy, A. C., Sczyrba, A., & Barton, M. D. (2015). Bioboxes: standardised containers for interchangeable bioinformatics software. GigaScience, 4(1), 47. https://doi.org/10.1186/s13742-015-0087-0
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2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2726156Paul, B. G., Bagby, S. C., Czornyj, E., Arambula, D., Handa, S., Sczyrba, A., Ghosh, P., et al. (2015). Targeted diversity generation by intraterrestrial archaea and archaeal viruses. Nature Communications, 6(1), 6585. doi:10.1038/ncomms7585
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2015 | Preprint | Veröffentlicht | PUB-ID: 2901613Lux, M., Hammer, B., & Sczyrba, A. (2015). Automated Contamination Detection in Single-Cell Sequencing. bioRxiv
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2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2762833Kohrs, F., Wolter, S., Benndorf, D., Heyer, R., Hoffmann, M., Rapp, E., Bremges, A., et al. (2015). Fractionation of biogas plant sludge material improves metaproteomic characterization to investigate metabolic activity of microbial communities. Proteomics, 15(20), 3585-3589. doi:10.1002/pmic.201400557
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2015 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 2901466Osterholz, B., Wiebke, P., Fust, A., Rumming, M., Schlüter, A., & Sczyrba, A. (2015). A Bioinformatics Pipeline for the Detection of β-lactamase Genes in Metagenome Sequence Data and its Application to Production-Scale Biogas Plants. Presented at the 3rd International Symposium on the environmental Dimension of Antibiotic Resistance, Wernigerode.
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2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2726183Field, E. K., Sczyrba, A., Lyman, A. E., Harris, C. C., Woyke, T., Stepanauskas, R., & Emerson, D. (2015). Genomic insights into the uncultivated marine Zetaproteobacteria at Loihi Seamount. The ISME journal, 9(4), 857-870. doi:10.1038/ismej.2014.183
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2015 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2901612Lux, M., Sczyrba, A., & Hammer, B. (2015). Automatic discovery of metagenomic structure. 2015 International Joint Conference on Neural Networks (IJCNN) Institute of Electrical & Electronics Engineers (IEEE). doi:10.1109/ijcnn.2015.7280500
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2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2685992Piao, H., Lachman, M., Malfatti, S., Sczyrba, A., Knierim, B., Auer, M., Tringe, S. G., et al. (2014). Temporal dynamics of fibrolytic and methanogenic rumen microorganisms during in situ incubation of switchgrass determined by 16S rRNA gene profiling. Frontiers in Microbiology, 5(307), 307. doi:10.3389/fmicb.2014.00307
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2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2698163Heins, R. A., Cheng, X., Nath, S., Deng, K., Bowen, B. P., Chivian, D. C., Datta, S., et al. (2014). Phylogenomically Guided Identification of Industrially Relevant GH1 β-Glucosidases through DNA Synthesis and Nanostructure-Initiator Mass Spectrometry. ACS chemical biology, 9(9), 2082-2091. doi:10.1021/cb500244v
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2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2654433Kamke, J., Rinke, C., Schwientek, P., Mavromatis, K., Ivanova, N., Sczyrba, A., Woyke, T., et al. (2014). The Candidate Phylum Poribacteria by Single-Cell Genomics: New Insights into Phylogeny, Cell-Compartmentation, Eukaryote-Like Repeat Proteins, and Other Genomic Features. PLoS ONE, 9(1), e87353. doi:10.1371/journal.pone.0087353
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2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2689051Ghylin, T. W., Garcia, S. L., Moya, F., Oyserman, B. O., Schwientek, P., Forest, K. T., Mutschler, J., et al. (2014). Comparative single-cell genomics reveals potential ecological niches for the freshwater acI Actinobacteria lineage. The ISME Journal, 8(12), 2503-2516. doi:10.1038/ismej.2014.135
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2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2672695Swan, B. K., Chaffin, M. D., Martinez-Garcia, M., Morrison, H. G., Field, E. K., Poulton, N. J., Masland, E. D. P., et al. (2014). Genomic and metabolic diversity of marine group I thaumarchaeota in the mesopelagic of two subtropical gyres. PloS one, 9(4), e95380. doi:10.1371/journal.pone.0095380
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2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2665333Henrich, B., Rumming, M., Sczyrba, A., Velleuer, E., Dietrich, R., Gerlach, W., Gombert, M., et al. (2014). Mycoplasma salivarium as a Dominant Coloniser of Fanconi Anaemia Associated Oral Carcinoma. PLoS ONE, 9(3), e92297. doi:10.1371/journal.pone.0092297
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2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2662055Wibberg, D., Luque-Almagro, V. M., Igeño, M. I., Bremges, A., Roldán, M. D., Merchán, F., Sáez, L. P., et al. (2014). Complete genome sequence of the cyanide-degrading bacterium Pseudomonas pseudoalcaligenes CECT5344. Journal of biotechnology, 175, 67-68. doi:10.1016/j.jbiotec.2014.02.004
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2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2638234Zaremba-Niedzwiedzka, K., Viklund, J., Zhao, W., Ast, J., Sczyrba, A., Woyke, T., McMahon, K., et al. (2013). Single-cell genomics reveal low recombination frequencies in freshwater bacteria of the SAR11 clade. Genome biology, 14(11), R130. doi:10.1186/gb-2013-14-11-r130
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2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2613567Rinke, C., Schwientek, P., Sczyrba, A., Ivanova, N. N., Anderson, I. J., Cheng, J. - F., Darling, A., et al. (2013). Insights into the phylogeny and coding potential of microbial dark matter. Nature, 499(7459), 431-437. doi:10.1038/nature12352
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2013 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2623500Gisbrecht, A., Hammer, B., Mokbel, B., & Sczyrba, A. (2013). Nonlinear dimensionality reduction for cluster identification in metagenomic samples. In E. Banissi (Ed.), 17th International Conference on Information Visualisation IV 2013 (pp. 174-179). Piscataway, NJ: IEEE. doi:10.1109/IV.2013.22
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2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2563543Campbell, A. G., Campbell, J. H., Schwientek, P., Woyke, T., Sczyrba, A., Allman, S., Beall, C. J., et al. (2013). Multiple Single-Cell Genomes Provide Insight into Functions of Uncultured Deltaproteobacteria in the Human Oral Cavity. PLoS ONE, 8(3), e59361. doi:10.1371/journal.pone.0059361
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2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2563424Campbell, J. H., O'Donoghue, P., Campbell, A. G., Schwientek, P., Sczyrba, A., Woyke, T., Söll, D., et al. (2013). UGA is an additional glycine codon in uncultured SR1 bacteria from the human microbiota. Proceedings of the National Academy of Sciences of the United States of America, 110(14), 5540-5545. doi:10.1073/pnas.1303090110
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2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2641352Kamke, J., Sczyrba, A., Ivanova, N., Schwientek, P., Rinke, C., Mavromatis, K., Woyke, T., et al. (2013). Single-cell genomics reveals complex carbohydrate degradation patterns in poribacterial symbionts of marine sponges. The ISME journal, 7(12), 2287-2300. https://doi.org/10.1038/ismej.2013.111
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2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2613623Swan, B. K., Tupper, B., Sczyrba, A., Lauro, F. M., Martinez-Garcia, M., González, J. M., Luo, H., et al. (2013). Prevalent genome streamlining and latitudinal divergence of planktonic bacteria in the surface ocean. Proceedings of the National Academy of Sciences of the United States of America, 110(28), 11463-11468. doi:10.1073/pnas.1304246110
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2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2518330Garcia, S. L., McMahon, K. D., Martinez-Garcia, M., Srivastava, A., Sczyrba, A., Stepanauskas, R., Grossart, H. - P., et al. (2012). Metabolic potential of a single cell belonging to one of the most abundant lineages in freshwater bacterioplankton. The ISME journal, 7(1), 137-147. doi:10.1038/ismej.2012.86
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2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2547307El-Kalioby, M., Abouelhoda, M., Krüger, J., Giegerich, R., Sczyrba, A., Wall, D. P., & Tonellato, P. (2012). Personalized cloud-based bioinformatics services for research and education: use cases and the elasticHPC package. BMC Bioinformatics, 13(Suppl 17), S22. doi:10.1186/1471-2105-13-S17-S22
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2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2410148Woyke, T., Sczyrba, A., Lee, J., Rinke, C., Tighe, D., Clingenpeel, S., Malmstrom, R., et al. (2011). Decontamination of MDA Reagents for Single Cell Whole Genome Amplification. PLoS ONE, 6(10), e26161. https://doi.org/10.1371/journal.pone.0026161
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2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2351462Kim, T. - W., Chokhawala, H. A., Hess, M., Dana, C. M., Baer, Z., Sczyrba, A., Rubin, E. M., et al. (2011). High-Throughput In Vitro Glycoside Hydrolase (HIGH) Screening for Enzyme Discovery. Angewandte Chemie, 123(47), 11411-11414. https://doi.org/10.1002/ange.201104685
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2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2329885Swan, B. K., Martinez-Garcia, M., Preston, C. M., Sczyrba, A., Woyke, T., Lamy, D., Reinthaler, T., et al. (2011). Potential for Chemolithoautotrophy Among Ubiquitous Bacteria Lineages in the Dark Ocean. Science, 333(6047), 1296-1300. https://doi.org/10.1126/science.1203690
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2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2789582Sales, C. M., Mahendra, S., Grostern, A., Parales, R. E., Goodwin, L. A., Woyke, T., Nolan, M., et al. (2011). Genome sequence of the 1,4-dioxane-degrading Pseudonocardia dioxanivorans strain CB1190. Journal of Bacteriology, 193(17), 4549-4550. doi:10.1128/JB.00415-11
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2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1991643Hess, M., Sczyrba, A., Egan, R., Kim, T. W., Chokhawala, H., Schroth, G., Luo, S., et al. (2011). Metagenomic discovery of biomass-degrading genes and genomes from cow rumen. Science, 331(6016), 463-467. https://doi.org/10.1126/science.1200387
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2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1991615Gilbert, J. A., Meyer, F., Antonopoulos, D., Balaji, P., Brown, C. T., Desai, N., Eisen, J. A., et al. (2010). Meeting report: the terabase metagenomics workshop and the vision of an Earth microbiome project. Stand Genomic Sci, 3(3), 243-248. https://doi.org/10.4056/sigs.1433550
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2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1784020Lamprecht, A. - L., Margaria, T., Steffen, B., Sczyrba, A., Hartmeier, S., & Giegerich, R. (2008). GeneFisher-P: variations of GeneFisher as processes in Bio-jETI. BMC Bioinformatics, 9(Suppl 4), S13. https://doi.org/10.1186/1471-2105-9-S4-S13
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2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1588303Sczyrba, A., Konermann, S., & Giegerich, R. (2008). Two interactive bioinformatics courses at the bielefeld university bioinformatics server. BRIEFINGS IN BIOINFORMATICS, 9(3), 243-249. https://doi.org/10.1093/bib/bbm063
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2006 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1599756Spitzer, M., Lorkowski, S., Cullen, P., Sczyrba, A., & Fuellen, G. (2006). IsoSVM - Distinguishing isoforms and paralogs on the protein level. BMC Bioinformatics, 7(1), 110. https://doi.org/10.1186/1471-2105-7-110
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2005 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1773613Sczyrba, A., Beckstette, M., Brivanlou, A. H., Giegerich, R., & Altmann, C. R. (2005). XenDB: Full length cDNA prediction and cross species mapping in Xenopus laevis. BMC Genomics, 6(1), 123. https://doi.org/10.1186/1471-2164-6-123
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2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2383529Beckstette, M., Mailänder, J. T., Marhöfer, R. J., Sczyrba, A., Ohlebusch, E., Giegerich, R., & Selzer, P. M. (2004). Genlight: Interactive high-throughput sequence analysis and comparative genomics. Journal of Integrative Bioinformatics, 1(1), 90-107. https://doi.org/10.2390/biecoll-jib-2004-8
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2004 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2383536Beckstette, M., Sczyrba, A., & Selzer, P. M. (2004). Genlight: Interactive high-throughput sequence analysis and comparative genomics. In R. Giegerich (Ed.), GI-Edition / Proceedings: Vol. 53. German Conference on Bioinformatics. GCB 2004 ; October 4 - 6, 2004, Bielefeld, Germany (pp. 179-186). Bonn: Gesellschaft für Informatik.
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2004 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2383561Sczyrba, A., Beckstette, M., Giegerich, R., & Altman, C. (2004). Identification of 10,500 Xenopus laevis Full Length Clones through EST Clustering and Sequence Analysis. In R. Giegerich & J. Stoye (Eds.), GI-Edition / Proceedings: Vol. 53. German Conference on Bioinformatics 2004 : GCB 2004, October 4 - 6, 2004, Bielefeld, Germany (pp. 6-7). Bonn: Gesellschaft für Informatik.
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2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1607400Taher, L., Rinner, O., Garg, S., Sczyrba, A., & Morgenstern, B. (2004). AGenDA: gene prediction by cross-species sequence comparison. Nucleic Acids Research, 32(Web Server), W305-W308. https://doi.org/10.1093/nar/gkh386
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2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1607394Krüger, J., Sczyrba, A., Kurtz, S., & Giegerich, R. (2004). e2g: an interactive web-based server for efficiently mapping large EST and cDNA sets to genomic sequences. NUCLEIC ACIDS RESEARCH, 32(Web Server), W301-W304. https://doi.org/10.1093/nar/gkh478
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2003 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1610494Taher, L., Rinner, O., Garg, S., Sczyrba, A., Brudno, M., Batzoglou, S., & Morgenstern, B. (2003). AGenDA: homology-based gene prediction. BIOINFORMATICS, 19(12), 1575-1577. https://doi.org/10.1093/bioinformatics/btg181
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2003 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1773844Sczyrba, A., Krüger, J., Mersch, H., Kurtz, S., & Giegerich, R. (2003). RNA-related tools on the Bielefeld Bioinformatics Server. Nucleic Acids Research, 31(13), 3767-3770. https://doi.org/10.1093/nar/gkg576
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2003 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1612470Morgenstern, B., Goel, S., Sczyrba, A., & Dress, A. (2003). AltAVisT: Comparing alternative multiple sequence alignments. BIOINFORMATICS, 19(3), 425-426. https://doi.org/10.1093/bioinformatics/btf882
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2003 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1609260Dondrup, M., Goesmann, A., Bartels, D., Kalinowski, J., Krause, L., Linke, B., Rupp, O., et al. (2003). EMMA: a platform for consistent storage and efficient analysis of microarray data. JOURNAL OF BIOTECHNOLOGY, 106(2-3), 135-146. https://doi.org/10.1016/j.jbiotec.2003.08.010
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2001 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1897716Gopal, S., Schroeder, M., Pieper, U., Sczyrba, A., Aytekin-Kurban, G., Bekiranov, S., Fajardo, J. E., et al. (2001). Homology-based annotation yields 1,042 new candidate genes in the Drosophila melanogaster genome. Nat Genet, 27(3), 337-340.
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2001 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1616752Altmann, C. R., Bell, E., Sczyrba, A., Pun, J., Bekiranov, S., Gaasterland, T., & Brivanlou, A. H. (2001). Microarray-based analysis of early development in Xenopus laevis. DEVELOPMENTAL BIOLOGY, 236(1), 64-75. https://doi.org/10.1006/dbio.2001.0298
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2000 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1897767Gaasterland, T., Sczyrba, A., Thomas, E., & Kurban, G. (2000). MAGPIE/EGRET annotation of the 2.9-Mb Drosophila melanogaster Adh region. Genome Res, 10(4), 502-510.