e2g: an interactive web-based server for efficiently mapping large EST and cDNA sets to genomic sequences

Krüger J, Sczyrba A, Kurtz S, Giegerich R (2004)
NUCLEIC ACIDS RESEARCH 32(Web Server): W301-W304.

Zeitschriftenaufsatz | Veröffentlicht | Englisch
 
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Abstract / Bemerkung
e2g is a web-based server which efficiently maps large expressed sequence tag (EST) and cDNA datasets to genomic DNA. It significantly extends the volume of data that can be mapped in reasonable time, and makes this improved efficiency available as a web service. Our server hosts large collections of EST sequences (e.g. 4.1 million mouse ESTs of 1.87 Gb) in precomputed indexed data structures for efficient sequence comparison. The user can upload a genomic DNA sequence of interest and rapidly compare this to the complete collection of ESTs on the server. This delivers a mapping of the ESTs on the genomic DNA. The e2g web interface provides a graphical overview of the mapping. Alignments of the mapped EST regions with parts of the genomic sequence are visualized. Zooming functions allow the user to interactively explore the results. Mapped sequences can be downloaded for further analysis. e2g is available on the Bielefeld University Bioinformatics Server at http://bibiserv.techfak.uni-bielefeld.de/e2g/.
Erscheinungsjahr
2004
Zeitschriftentitel
NUCLEIC ACIDS RESEARCH
Band
32
Ausgabe
Web Server
Seite(n)
W301-W304
ISSN
0305-1048
eISSN
1362-4962
Page URI
https://pub.uni-bielefeld.de/record/1607394

Zitieren

Krüger J, Sczyrba A, Kurtz S, Giegerich R. e2g: an interactive web-based server for efficiently mapping large EST and cDNA sets to genomic sequences. NUCLEIC ACIDS RESEARCH. 2004;32(Web Server):W301-W304.
Krüger, J., Sczyrba, A., Kurtz, S., & Giegerich, R. (2004). e2g: an interactive web-based server for efficiently mapping large EST and cDNA sets to genomic sequences. NUCLEIC ACIDS RESEARCH, 32(Web Server), W301-W304. https://doi.org/10.1093/nar/gkh478
Krüger, Jan, Sczyrba, Alexander, Kurtz, Stefan, and Giegerich, Robert. 2004. “e2g: an interactive web-based server for efficiently mapping large EST and cDNA sets to genomic sequences”. NUCLEIC ACIDS RESEARCH 32 (Web Server): W301-W304.
Krüger, J., Sczyrba, A., Kurtz, S., and Giegerich, R. (2004). e2g: an interactive web-based server for efficiently mapping large EST and cDNA sets to genomic sequences. NUCLEIC ACIDS RESEARCH 32, W301-W304.
Krüger, J., et al., 2004. e2g: an interactive web-based server for efficiently mapping large EST and cDNA sets to genomic sequences. NUCLEIC ACIDS RESEARCH, 32(Web Server), p W301-W304.
J. Krüger, et al., “e2g: an interactive web-based server for efficiently mapping large EST and cDNA sets to genomic sequences”, NUCLEIC ACIDS RESEARCH, vol. 32, 2004, pp. W301-W304.
Krüger, J., Sczyrba, A., Kurtz, S., Giegerich, R.: e2g: an interactive web-based server for efficiently mapping large EST and cDNA sets to genomic sequences. NUCLEIC ACIDS RESEARCH. 32, W301-W304 (2004).
Krüger, Jan, Sczyrba, Alexander, Kurtz, Stefan, and Giegerich, Robert. “e2g: an interactive web-based server for efficiently mapping large EST and cDNA sets to genomic sequences”. NUCLEIC ACIDS RESEARCH 32.Web Server (2004): W301-W304.
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Dieses Objekt ist durch das Urheberrecht und/oder verwandte Schutzrechte geschützt. [...]
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7 Zitationen in Europe PMC

Daten bereitgestellt von Europe PubMed Central.

ESTPiper--a web-based analysis pipeline for expressed sequence tags.
Tang Z, Choi JH, Hemmerich C, Sarangi A, Colbourne JK, Dong Q., BMC Genomics 10(), 2009
PMID: 19383159
Repeats and EST analysis for new organisms.
Malde K, Jonassen I., BMC Genomics 9(), 2008
PMID: 18205940
MapToGenome: a comparative genomic tool that aligns transcript maps to sequenced genomes.
Putta S, Smith JJ, Staben C, Voss SR., Evol Bioinform Online 3(), 2007
PMID: 19430601
XML schemas for common bioinformatic data types and their application in workflow systems.
Seibel PN, Krüger J, Hartmeier S, Schwarzer K, Löwenthal K, Mersch H, Dandekar T, Giegerich R., BMC Bioinformatics 7(), 2006
PMID: 17087823
EST-BASED ANALYSIS OF GENE EXPRESSION IN THE HUMAN COCHLEA.
Gabashvili IS, Carter RJ, Markstein P, Giersch ABS., Workshops Poster Abstr 2005(), 2005
PMID: 28967002
XenDB: full length cDNA prediction and cross species mapping in Xenopus laevis.
Sczyrba A, Beckstette M, Brivanlou AH, Giegerich R, Altmann CR., BMC Genomics 6(), 2005
PMID: 16162280

11 References

Daten bereitgestellt von Europe PubMed Central.

A computer program for aligning a cDNA sequence with a genomic DNA sequence.
Florea L, Hartzell G, Zhang Z, Rubin GM, Miller W., Genome Res. 8(9), 1998
PMID: 9750195
Optimal spliced alignment of homologous cDNA to a genomic DNA template.
Usuka J, Zhu W, Brendel V., Bioinformatics 16(3), 2000
PMID: 10869013
Gene2EST: a BLAST2 server for searching expressed sequence tag (EST) databases with eukaryotic gene-sized queries.
Gemund C, Ramu C, Altenberg-Greulich B, Gibson TJ., Nucleic Acids Res. 29(6), 2001
PMID: 11238992
BLAT--the BLAST-like alignment tool.
Kent WJ., Genome Res. 12(4), 2002
PMID: 11932250
cDNA2Genome: a tool for mapping and annotating cDNAs.
Del Val C, Glatting KH, Suhai S., BMC Bioinformatics 4(), 2003
PMID: 12964951
MGAlignIt: A web service for the alignment of mRNA/EST and genomic sequences.
Lee BT, Tan TW, Ranganathan S., Nucleic Acids Res. 31(13), 2003
PMID: 12824360

AUTHOR UNKNOWN, 0
Prediction of complete gene structures in human genomic DNA.
Burge C, Karlin S., J. Mol. Biol. 268(1), 1997
PMID: 9149143

AUTHOR UNKNOWN, 0
A greedy algorithm for aligning DNA sequences.
Zhang Z, Schwartz S, Wagner L, Miller W., J. Comput. Biol. 7(1-2), 2000
PMID: 10890397
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