73 Publikationen

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  • [73]
    2021 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2957097 OA
    Shankar, R., Schäffer, N., Schmeer, M., Friehs, K., Risse, J.M., Schleef, M.: Recombinant expression of Barnase in Escherichia coli and its application in plasmid purification. Microbial Cell Factories. 20, : 171 (2021).
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  • [72]
    2021 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2958416 OA
    Luttermann, T., Rückert, C., Wibberg, D., Busche, T., Schwarzhans, J.-P., Friehs, K., Kalinowski, J.: Establishment of a near-contiguous genome sequence of the citric acid producing yeast DSM 3286 with resolution of rDNA clusters and telomeres. NAR Genomics and Bioinformatics. 3, 13 (2021).
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  • [71]
    2021 | Patent | PUB-ID: 2965425
    Risse, J.M., Friehs, K., Wedde, S., Hahn, M., Ludwig, B.: Expression of collagen peptide components in procaryotic systems. 11.11.2021.
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  • [70]
    2021 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2957893
    Shankar, R., Schafer, N., Schmeer, M., Risse, J.M., Friehs, K., Schleef, M.: Correction to: Recombinant expression of Barnase in Escherichia coli and its application in plasmid purifcation. Microbial Cell Factories. 20, : 190 (2021).
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [69]
    2020 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2945772 OA
    Heß, M., Bloess, S., Risse, J.M., Friehs, K., Fischer von Mollard, G.: Recombinant expression of an l-amino acid oxidase from the fungus Hebeloma cylindrosporum in Pichia pastoris including fermentation. MicrobiologyOpen. 9, : e1112 (2020).
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  • [68]
    2020 | Datenpublikation | PUB-ID: 2944932 OA
    Heß, M., Bloess, S., Risse, J.M., Friehs, K., Fischer von Mollard, G.: Data for 'Recombinant expression of an L-amino acid oxidase from the fungus Hebeloma cylindrosporum in Pichia pastoris including fermentation'. Bielefeld University (2020).
    PUB | Dateien verfügbar | DOI
     
  • [67]
    2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2930505
    Kleiner-Grote, G., Risse, J.M., Friehs, K.: Secretion of recombinant proteins from E. coli. ENGINEERING IN LIFE SCIENCES. 18, 532-550 (2018).
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [66]
    2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2910668 OA
    Friehs, K., Schwarzhans, J.P., Luttermann, T., Wibberg, D., Winkler, A., Hübner, W., Huser, T., Kalinowski, J.: A Mitochondrial Autonomously Replicating Sequence from Pichia pastoris for Uniform High Level Recombinant Protein Production. Frontiers in Microbiology. 8, : 780 (2017).
    PUB | PDF | DOI | WoS | PubMed | Europe PMC
     
  • [65]
    2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2916444
    Schwarzhans, J.P., Luttermann, T., Geier, M., Kalinowski, J., Friehs, K.: Towards systems metabolic engineering in Pichia pastoris. BIOTECHNOLOGY ADVANCES. 35, 681-710 (2017).
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [64]
    2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2908307
    Perez, F., Risse, J.M., Friehs, K., Wendisch, V.F.: Fermentative production of L-pipecolic acid from glucose and alternative carbon sources. Biotechnology Journal. 12, : 1600646 (2017).
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [63]
    2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2903655 OA
    Schwarzhans, J.P., Wibberg, D., Winkler, A., Luttermann, T., Kalinowski, J., Friehs, K.: Integration event induced changes in recombinant protein productivity in Pichia pastoris discovered by whole genome sequencing and derived vector optimization. Microbial Cell Factories. 15, : 84 (2016).
    PUB | PDF | DOI | WoS | PubMed | Europe PMC
     
  • [62]
    2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2907679 OA
    Schwarzhans, J.P., Wibberg, D., Winkler, A., Luttermann, T., Kalinowski, J., Friehs, K.: Non-canonical integration events in Pichia pastoris encountered during standard transformation analysed with genome sequencing. Scientific Reports. 6, : 38952 (2016).
    PUB | PDF | DOI | WoS | PubMed | Europe PMC
     
  • [61]
    2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2903023
    Wetzel, D., Müller, J., Flaschel, E., Friehs, K., Risse, J.M.: Fed-batch production and secretion of streptavidin by Hansenula polymorpha: Evaluation of genetic factors and bioprocess development. JOURNAL OF BIOTECHNOLOGY. 225, 3-9 (2016).
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [60]
    2016 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2906700
    Holtmann, D., Vernen, F., Müller, J., Kaden, D., Risse, J.M., Friehs, K., Dähne, L., Stratmann, A., Schrader, J.: Effects of particle addition to Streptomyces cultivations to optimize the production of actinorhodin and streptavidin. Sustainable Chemistry and Pharmacy. 5, 67-71 (2016).
    PUB | DOI | WoS
     
  • [59]
    2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2906197
    Müller, J., Bruhn, S., Flaschel, E., Friehs, K., Risse, J.M.: GAP promoter-based fed-batch production of highly bioactive core streptavidin by Pichia pastoris. BIOTECHNOLOGY PROGRESS. 32, 855-864 (2016).
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [58]
    2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2900637
    Müller, J., Wetzel, D., Flaschel, E., Friehs, K., Risse, J.M.: Constitutive production and efficient secretion of soluble full-length streptavidin by an Escherichia coli 'leaky mutant'. Journal of Biotechnology. 221, 91-100 (2016).
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  • [57]
    2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2767378
    Müller, J., Risse, J.M., Friehs, K., Flaschel, E.: Model-based development of an assay for the rapid detection of biotin-blocked binding sites of streptavidin. Engineering in Life Sciences. 15, 627-639 (2015).
    PUB | DOI | WoS
     
  • [56]
    2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2759080
    Grimm, P., Risse, J.M., Müller, J., Cholewa, D., Beshay, U., Friehs, K., Flaschel, E.: Applicability of Euglena gracilis for biorefineries demonstrated by the production of α-tocopherol and paramylon followed by anaerobic digestion. Journal of Biotechnology. 215, 72-79 (2015).
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [55]
    2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2722001
    Schwarzhans, J.P., Cholewa, D., Grimm, P., Beshay, U., Risse, J.M., Friehs, K., Flaschel, E.: Dependency of the fatty acid composition of Euglena gracilis on growth phase and culture conditions. Journal of Applied Phycology. 27, 1389-1399 (2015).
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  • [54]
    2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2679910 OA
    Selvamani, R.S.V., Telaar, M., Friehs, K., Flaschel, E.: Antibiotic-free segregational plasmid stabilization in Escherichia coli owing to the knockout of triosephosphate isomerase (tpiA). Microbial Cell Factories. 13, : 58 (2014).
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  • [53]
    2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2675672
    Selvamani, R.S.V., Friehs, K., Flaschel, E.: Extracellular recombinant protein production under continuous culture conditions with Escherichia coli using an alternative plasmid selection mechanism. Bioprocess and Biosystems Engineering. 37, 401-413 (2014).
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  • [52]
    2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2474324
    Santek, B., Friehs, K., Lotz, M., Flaschel, E.: Production of paramylon, a ss-1,3-glucan, by heterotrophic growth of Euglena gracilis on potato liquor in fed-batch and repeated-batch mode of cultivation. Engineering in Life Sciences. 12, 89-94 (2012).
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  • [51]
    2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2401962
    Risse, J.M., Friehs, K.: Sekretion und Affinitätschromatografie rekombinanter Proteine. BIOspektrum. 5, 550-552 (2010).
    PUB
     
  • [50]
    2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1796536
    Sommer, B., Friehs, K., Flaschel, E.: Efficient production of extracellular proteins with Escherichia coli by means of optimized coexpression of bacteriocin release proteins. JOURNAL OF BIOTECHNOLOGY. 145, 350-358 (2010).
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  • [49]
    2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1795042
    Santek, B., Felski, M., Friehs, K., Lotz, M., Flaschel, E.: Production of paramylon, a beta-1,3-glucan, by heterotrophic cultivation of Euglena gracilis on potato liquor. ENGINEERING IN LIFE SCIENCES. 10, NA (2010).
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  • [48]
    2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1635287
    Santek, B., Felski, M., Friehs, K., Lotz, M., Flaschel, E.: Production of paramylon, a beta-1,3-glucan, by heterotrophic cultivation of Euglena gracilis on a synthetic medium. ENGINEERING IN LIFE SCIENCES. 9, 23-28 (2009).
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  • [47]
    2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1636091
    Beshay, U., Miksch, G., Friehs, K., Flaschel, E.: Integrated bioprocess for the production and purification of recombinant proteins by affinity chromatography in Escherichia coli. BIOPROCESS AND BIOSYSTEMS ENGINEERING. 32, 149-158 (2009).
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  • [46]
    2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1634165
    Sommer, B., Friehs, K., Flaschel, E., Reck, M., Stahl, F., Scheper, T.: Extracellular production and affinity purification of recombinant proteins with Escherichia coli using the versatility of the maltose binding protein. JOURNAL OF BIOTECHNOLOGY. 140, 194-202 (2009).
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  • [45]
    2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1585399
    Beshay, U., Friehs, K., Flaschel, E.: Growth of myxamoebae of the cellular slime mold Dictyostelium discoideum in suspension and immobilized form on living bacteria. PROCESS BIOCHEMISTRY. 43, 1281-1287 (2008).
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  • [44]
    2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1585611 OA
    Wei, N., Flaschel, E., Friehs, K., Nattkemper, T.W.: A machine vision system for automated non-invasive assessment of cell viability via dark field microscopy, wavelet feature selection and classification. BMC Bioinformatics. 9, 449 (2008).
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  • [43]
    2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1587590 OA
    Vijayendran, C., Barsch, A., Friehs, K., Niehaus, K., Becker, A., Flaschel, E.: Perceiving molecular evolution processes in Escherichia coli by comprehensive metabolite and gene expression profiling. GENOME BIOLOGY. 9, R72 (2008).
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  • [42]
    2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1631667 OA
    Vijayendran, C., Burgemeister, S., Friehs, K., Niehaus, K., Flaschel, E.: 2DBase: 2D-PAGE database of Escherichia coli. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 363, 822-827 (2007).
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  • [41]
    2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1594835
    Vijayendran, C., Polen, T., Wendisch, V.F., Friehs, K., Niehaus, K., Flaschel, E.: The plasticity of global proteome and genome expression analyzed in closely related W3110 and MG1655 strains of a well-studied model organism, Escherichia coli-K12. Journal of Biotechnology. 128, 747-761 (2007).
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  • [40]
    2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1595739
    Wei, N., You, J., Friehs, K., Flaschel, E., Nattkemper, T.W.: In situ dark field microscopy for on-line monitoring of yeast cultures. BIOTECHNOLOGY LETTERS. 29, 373-378 (2007).
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  • [39]
    2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1593120
    Wei, N., You, J., Friehs, K., Flaschel, E., Nattkemper, T.W.: An in situ probe for on-line monitoring of cell density and viability on the basis of dark field microscopy in conjunction with image processing and supervised machine learning. Biotechnology and Bioengineering. 97, 1489-1500 (2007).
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  • [38]
    2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1593482
    Beshay, U., Miksch, G., Friehs, K., Flaschel, E.: Improved beta-glucanase production by a recombinant Escherichia coli strain using a zinc-ion supplemented medium. ENGINEERING IN LIFE SCIENCES. 7, 253-258 (2007).
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  • [37]
    2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1631107
    Blaesen, M., Friehs, K., Flaschel, E.: Recycling of bacterial biomass in a process of L-threonine production by means of a recombinant strain of Escherichia coli. JOURNAL OF BIOTECHNOLOGY. 132, 431-437 (2007).
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  • [36]
    2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1631661
    Beshay, U., Miksch, G., Friehs, K., Flaschel, E.: Increasing the secretion ability of the kil gene for recombinant proteins in Escherichia coli by using a strong stationary-phase promoter. BIOTECHNOLOGY LETTERS. 29, 1893-1901 (2007).
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  • [35]
    2006 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1600329
    Miksch, G., Bettenworth, F., Friehs, K., Flaschel, E., Saalbach, A., Nattkemper, T.W.: A rapid reporter system using GFP as a reporter protein for identification and screening of synthetic stationary-phase promoters in Escherichia coli. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY. 70, 229-236 (2006).
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  • [34]
    2006 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1597472
    Blaesen, M., Flaschel, E., Friehs, K.: Sustainable production: Recycling of bacterial biomass resulting from a fermentation process with Klebsiella planticola. CHEMICAL AND BIOCHEMICAL ENGINEERING QUARTERLY. 20, 263-268 (2006).
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  • [33]
    2005 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2906664
    Polen, T., Wendisch, V.F., Friehs, K., Niehaus, K., Flaschel, E., Vijayendran, C.: The plasticity of global proteome and genome expression analysis in a well studied closely related model organism, Escherichia coli. MOLECULAR & CELLULAR PROTEOMICS. 4, S248-S248 (2005).
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  • [32]
    2005 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1604386
    Arndt, M., Kleist, S., Miksch, G., Friehs, K., Flaschel, E., Trierweiler, J., Hitzmann, B.: A feedforward-feedback substrate controller based on a Kalman filter for a fed-batch cultivation of Escherichia coli producing phytase. COMPUTERS & CHEMICAL ENGINEERING. 29, 1113-1120 (2005).
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  • [31]
    2005 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1601074
    Miksch, G., Bettenworth, F., Friehs, K., Flaschel, E.: The sequence upstream of the -10 consensus sequence modulates the strength and induction time of stationary-phase promoters in Escherichia coli. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY. 69, 312-320 (2005).
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  • [30]
    2005 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 1601848
    Miksch, G., Bettenworth, F., Friehs, K., Flaschel, E., Saalbach, A., Twellmann, T., Nattkemper, T.W.: Libraries of synthetic stationary-phase and stress promoters as a tool for fine-tuning of expression of recombinant proteins in Escherichia coli. Journal of Biotechnology. JOURNAL OF BIOTECHNOLOGY. 120, p. 25-37. ELSEVIER SCIENCE BV (2005).
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  • [29]
    2005 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 1601124
    Vijayendran, C., Polen, T., Wendisch, V., Friehs, K., Niehaus, K., Flaschel, E.: The plasticity of global proteome and genome expression analysis in a well studied closely related model organism, Escherichia coli. Molecular & Cellular Proteomics. 4, S248 (2005).
    PUB | WoS
     
  • [28]
    2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1608845
    Han, S.I., Friehs, K., Flaschel, E.: Cultivation of Dictyostelium discoideum on an improved synthetic medium in a conventional bioreactor. PROCESS BIOCHEMISTRY. 39, 585-589 (2004).
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  • [27]
    2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1607969
    Han, S.I., Friehs, K., Flaschel, E.: Improvement of a synthetic medium for Dictyostelium discoideum. PROCESS BIOCHEMISTRY. 39, 925-930 (2004).
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  • [26]
    2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1609051
    Voß, C., Schmidt, T., Schleef, M., Friehs, K., Flaschel, E.: Effect of ammonium chloride on plasmid DNA production in high cell density batch culture for biopharmaceutical use. JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY. 79, 57-62 (2004).
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  • [25]
    2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1608382
    Lu, Y.H., Knol, J.C., Linskens, M.H.K., Friehs, K., van Haastert, P.J.M., Flaschel, E.: Production of the soluble human Fas ligand by Dictyostelium discoideum cultivated on a synthetic medium. JOURNAL OF BIOTECHNOLOGY. 108, 243-251 (2004).
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  • [24]
    2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1606278
    Lu, Y.H., Knol, J.C., Linskens, M.H.K., Friehs, K., van Haastert, P.J.M., Flaschel, E.: Cultivation of immobilized Dictyostelium discoideum for the production of soluble human Fas ligand. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY. 65, 547-552 (2004).
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  • [23]
    2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1606443
    Lu, Y.H., Beshay, U., Friehs, K., Flaschel, E.: Mass production of Dictyostelium discoideum in homogenous and hetergeneous cultivation systems. PROCESS BIOCHEMISTRY. 39, 1859-1870 (2004).
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  • [22]
    2003 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1609437
    Beshay, U., Friehs, K., Azzam, A.E.M., Flaschel, E.: Analysis of the behaviour of Dictyostelium discoideum in immobilised state by means of continuous cultivation. BIOPROCESS AND BIOSYSTEMS ENGINEERING. 26, 117-122 (2003).
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  • [21]
    2003 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1610824
    Beshay, U., Friehs, K., Azzam, A.E.M., Flaschel, E.: Cultivation of Dictyostelium discoideum in immobilized form by colonization of porous supports. PROCESS BIOCHEMISTRY. 38, 1521-1529 (2003).
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  • [20]
    2003 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1609656
    Voß, C., Schmidt, T., Schleef, M., Friehs, K., Flaschel, E.: Production of supercoiled multimeric plasmid DNA for biopharmaceutical application. JOURNAL OF BIOTECHNOLOGY. 105, 205-213 (2003).
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  • [19]
    2003 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1609485
    Stephan, M., Beshay, U., Friehs, K., Flaschel, E.: Influence of medium composition on growth behaviour of Dictyostelium discoideum for cultivation on axenic media. PROCESS BIOCHEMISTRY. 39, 333-343 (2003).
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  • [18]
    2002 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1880734
    Schierl, F., Friehs, K., Risse, J.M., Flaschel, E.: Herstellung von Mediumskomponenten aus mikrobieller Biomasse. Freiberger Forschungshefte. A 866, 112-124 (2002).
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  • [17]
    2002 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1613472
    Miksch, G., Kleist, S., Friehs, K., Flaschel, E.: Overexpression of the phytase from Escherichia coli and its extracellular production in bioreactors. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY. 59, 685-694 (2002).
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  • [16]
    2001 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1880242
    Risse, J.M., Friehs, K., Flaschel, E.: Recycling of Biomass Resulting from Fermentation Processes with Bacillus licheniformis. Chem. Eng. Technol. 24, 141-145 (2001).
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  • [15]
    2000 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1619389
    Risse, J.M., Friehs, K., Flaschel, E.: Biomasserückführung am Beispiel Bacillus licheniformis. CHEMIE INGENIEUR TECHNIK. 72, 750-754 (2000).
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  • [14]
    1999 | Bielefelder E-Habilitation | PUB-ID: 2305466 OA
    Friehs, K.: Maßnahmen zur Verbesserung der Produktion von rekombinanten Proteinen und Plasmid-DNS. Bielefeld University, Bielefeld (Germany) (1999).
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  • [13]
    1999 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1621612
    Schmidt, T., Friehs, K., Schleef, M., Voß, C., Flaschel, E.: Quantitative analysis of plasmid forms by agarose and capillary gel electrophoresis. ANALYTICAL BIOCHEMISTRY. 274, 235-240 (1999).
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  • [12]
    1999 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1622862
    Miksch, G., Neitzel, R., Friehs, K., Flaschel, E.: High-level expression of a recombinant protein in Klebsiella planticola owing to induced secretion into the culture medium. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY. 51, 627-632 (1999).
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  • [11]
    1998 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1625697
    Friehs, K., Schierl, F., Flaschel, E.: Reprocessing of bacterial biomass for recycling as a medium component in fermentation processes. CHEMIE INGENIEUR TECHNIK. 70, 435-437 (1998).
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  • [10]
    1997 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1637759
    Miksch, G., Neitzel, R., Fiedler, E., Friehs, K., Flaschel, E.: Extracellular production of a hybrid beta-glucanase from Bacillus by Escherichia coli under different cultivation conditions in shaking cultures and bioreactors. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY. 47, 120-126 (1997).
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  • [9]
    1997 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1627108
    Poppenborg, L., Friehs, K., Flaschel, E.: The green fluorescent protein is a versatile reporter for bioprocess monitoring. JOURNAL OF BIOTECHNOLOGY. 58, 79-88 (1997).
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  • [8]
    1996 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1628395
    Schmidt, T., Friehs, K., Flaschel, E.: Rapid determination of plasmid copy number. JOURNAL OF BIOTECHNOLOGY. 49, 219-229 (1996).
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [7]
    1996 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 1639656
    Schmidt, T., Friehs, K., Flaschel, E.: Plasmid copy number as a process variable for fermentation control. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. 211, 191-BIOT (1996).
    PUB | WoS
     
  • [6]
    1993 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1646173 OA
    Flaschel, E., Friehs, K.: Improvement of downstream processing of recombinant proteins by means of genetic engineering. Biotechnology Advances. 11, 31-77 (1993).
    PUB | PDF | DOI | WoS | PubMed | Europe PMC
     
  • [5]
    1993 | Sammelwerksbeitrag | Veröffentlicht | PUB-ID: 1782559 OA
    Reardon, K.F., Friehs, K.: Parameters influencing the productivity of recombinant E. coli cultivations. In: Aarts, R. (ed.) Bioprocess design and control. Advances in biochemical engineering, biotechnology ; 48. p. 53-77. Springer, Berlin [u.a.] (1993).
    PUB | PDF | PubMed | Europe PMC
     
  • [4]
    1991 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1782553 OA
    Kumar, P.K.R., Maschke, H.-E., Friehs, K., Schügerl, K.: Strategies for improving plasmid stability in genetically modified bacteria in bioreactors. Trends in biotechnology. 9, 279-284 (1991).
    PUB | PDF | DOI | WoS | PubMed | Europe PMC
     
  • [3]
    1989 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1782550 OA
    Friehs, K., Bailey, J.E.: Unusual observations during construction of a new cloning vector providing lon gene expression in Escherichia coli. Journal of Biotechnology. 9, 305-316 (1989).
    PUB | PDF | DOI | WoS
     
  • [2]
    1989 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1782547 OA
    Friehs, K., Lafferty, R.M.: Cloning and expression of the levanase gene in Alcaligenes eutrophus H16 enables the strain to hydrolyze sucrose. Journal of Biotechnology. 10, 285-291 (1989).
    PUB | PDF | DOI | WoS
     
  • [1]
    1986 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1782542 OA
    Friehs, K., Schörgendorfer, K., Schwab, H., Lafferty, R.M.: Cloning and phenotypic expression in Escherichia coli of a Bacillus subtilis gene fragment coding for sucrose hydrolysis. Journal of Biotechnology. 3, 333-341 (1986).
    PUB | PDF | DOI | WoS
     

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