67 Publikationen

Alle markieren

[67]
2018 | Zeitschriftenaufsatz | PUB-ID: 2930505
Secretion of recombinant proteins from E. coli
Kleiner-Grote G, Risse JM, Friehs K (2018)
ENGINEERING IN LIFE SCIENCES 18(8): 532-550.
PUB | DOI | WoS
 
[66]
2017 | Zeitschriftenaufsatz | PUB-ID: 2916444
Towards systems metabolic engineering in Pichia pastoris
Schwarzhans JP, Luttermann T, Geier M, Kalinowski J, Friehs K (2017)
BIOTECHNOLOGY ADVANCES 35(6): 681-710.
PUB | DOI | WoS | PubMed | Europe PMC
 
[65]
2017 | Zeitschriftenaufsatz | PUB-ID: 2908307
Fermentative production of L-pipecolic acid from glucose and alternative carbon sources
Perez F, Risse JM, Friehs K, Wendisch VF (2017)
Biotechnology Journal 12(7): 1600646.
PUB | DOI | WoS | PubMed | Europe PMC
 
[64]
2017 | Zeitschriftenaufsatz | PUB-ID: 2910668
A Mitochondrial Autonomously Replicating Sequence from Pichia pastoris for Uniform High Level Recombinant Protein Production
Friehs K, Schwarzhans JP, Luttermann T, Wibberg D, Winkler A, Hübner W, Huser T, Kalinowski J (2017)
Frontiers in Microbiology 8: 780.
PUB | PDF | DOI | WoS | PubMed | Europe PMC
 
[63]
2016 | Zeitschriftenaufsatz | PUB-ID: 2907679
Non-canonical integration events in Pichia pastoris encountered during standard transformation analysed with genome sequencing
Schwarzhans JP, Wibberg D, Winkler A, Luttermann T, Kalinowski J, Friehs K (2016)
Scientific Reports 6: 38952.
PUB | PDF | DOI | WoS | PubMed | Europe PMC
 
[62]
2016 | Zeitschriftenaufsatz | PUB-ID: 2903655
Integration event induced changes in recombinant protein productivity in Pichia pastoris discovered by whole genome sequencing and derived vector optimization
Schwarzhans JP, Wibberg D, Winkler A, Luttermann T, Kalinowski J, Friehs K (2016)
Microbial Cell Factories 15: 84.
PUB | PDF | DOI | WoS | PubMed | Europe PMC
 
[61]
2016 | Zeitschriftenaufsatz | PUB-ID: 2903023
Fed-batch production and secretion of streptavidin by Hansenula polymorpha: Evaluation of genetic factors and bioprocess development
Wetzel D, Müller J, Flaschel E, Friehs K, Risse JM (2016)
JOURNAL OF BIOTECHNOLOGY 225: 3-9.
PUB | DOI | WoS | PubMed | Europe PMC
 
[60]
2016 | Zeitschriftenaufsatz | PUB-ID: 2906700
Effects of particle addition to Streptomyces cultivations to optimize the production of actinorhodin and streptavidin
Holtmann D, Vernen F, Müller J, Kaden D, Risse JM, Friehs K, Dähne L, Stratmann A, Schrader J (2016)
Sustainable Chemistry and Pharmacy.
PUB | DOI | WoS
 
[59]
2016 | Zeitschriftenaufsatz | PUB-ID: 2906197
GAP promoter-based fed-batch production of highly bioactive core streptavidin by Pichia pastoris
Müller J, Bruhn S, Flaschel E, Friehs K, Risse JM (2016)
BIOTECHNOLOGY PROGRESS 32(4): 855-864.
PUB | DOI | WoS | PubMed | Europe PMC
 
[58]
2016 | Zeitschriftenaufsatz | PUB-ID: 2900637
Constitutive production and efficient secretion of soluble full-length streptavidin by an Escherichia coli 'leaky mutant'
Müller J, Wetzel D, Flaschel E, Friehs K, Risse JM (2016)
Journal of Biotechnology 221: 91-100.
PUB | DOI | WoS | PubMed | Europe PMC
 
[57]
2015 | Zeitschriftenaufsatz | PUB-ID: 2767378
Model-based development of an assay for the rapid detection of biotin-blocked binding sites of streptavidin
Müller J, Risse JM, Friehs K, Flaschel E (2015)
Engineering in Life Sciences 15(6): 627-639.
PUB | DOI | WoS
 
[56]
2015 | Zeitschriftenaufsatz | PUB-ID: 2759080
Applicability of Euglena gracilis for biorefineries demonstrated by the production of α-tocopherol and paramylon followed by anaerobic digestion
Grimm P, Risse JM, Müller J, Cholewa D, Beshay U, Friehs K, Flaschel E (2015)
Journal of Biotechnology 215: 72-79.
PUB | DOI | WoS | PubMed | Europe PMC
 
[55]
2015 | Zeitschriftenaufsatz | PUB-ID: 2722001
Dependency of the fatty acid composition of Euglena gracilis on growth phase and culture conditions
Schwarzhans JP, Cholewa D, Grimm P, Beshay U, Risse JM, Friehs K, Flaschel E (2015)
Journal of Applied Phycology 27(4): 1389-1399.
PUB | DOI | WoS
 
[54]
2014 | Zeitschriftenaufsatz | PUB-ID: 2679910
Antibiotic-free segregational plasmid stabilization in Escherichia coli owing to the knockout of triosephosphate isomerase (tpiA)
Selvamani RSV, Telaar M, Friehs K, Flaschel E (2014)
Microbial Cell Factories 13: 58.
PUB | PDF | DOI | WoS | PubMed | Europe PMC
 
[53]
2014 | Zeitschriftenaufsatz | PUB-ID: 2675672 PUB | DOI | WoS | PubMed | Europe PMC
 
[52]
2012 | Zeitschriftenaufsatz | PUB-ID: 2474324 PUB | DOI | WoS
 
[51]
2010 | Zeitschriftenaufsatz | PUB-ID: 2401962
Sekretion und Affinitätschromatografie rekombinanter Proteine
Risse JM, Friehs K (2010)
BIOspektrum 5: 550-552.
PUB
 
[50]
2010 | Zeitschriftenaufsatz | PUB-ID: 1796536 PUB | DOI | WoS | PubMed | Europe PMC
 
[49]
2010 | Zeitschriftenaufsatz | PUB-ID: 1795042
Production of paramylon, a beta-1,3-glucan, by heterotrophic cultivation of Euglena gracilis on potato liquor
Santek B, Felski M, Friehs K, Lotz M, Flaschel E (2010)
ENGINEERING IN LIFE SCIENCES 10(2): NA.
PUB | DOI | WoS
 
[48]
2009 | Zeitschriftenaufsatz | PUB-ID: 1635287
Production of paramylon, a beta-1,3-glucan, by heterotrophic cultivation of Euglena gracilis on a synthetic medium
Santek B, Felski M, Friehs K, Lotz M, Flaschel E (2009)
ENGINEERING IN LIFE SCIENCES 9(1): 23-28.
PUB | DOI | WoS
 
[47]
2009 | Zeitschriftenaufsatz | PUB-ID: 1634165
Extracellular production and affinity purification of recombinant proteins with Escherichia coli using the versatility of the maltose binding protein
Sommer B, Friehs K, Flaschel E, Reck M, Stahl F, Scheper T (2009)
JOURNAL OF BIOTECHNOLOGY 140(3-4): 194-202.
PUB | DOI | WoS | PubMed | Europe PMC
 
[46]
2009 | Zeitschriftenaufsatz | PUB-ID: 1636091
Integrated bioprocess for the production and purification of recombinant proteins by affinity chromatography in Escherichia coli
Beshay U, Miksch G, Friehs K, Flaschel E (2009)
BIOPROCESS AND BIOSYSTEMS ENGINEERING 32(2): 149-158.
PUB | DOI | WoS | PubMed | Europe PMC
 
[45]
2008 | Zeitschriftenaufsatz | PUB-ID: 1585399 PUB | DOI | WoS
 
[44]
2008 | Zeitschriftenaufsatz | PUB-ID: 1585611 PUB | PDF | DOI | WoS | PubMed | Europe PMC
 
[43]
2008 | Zeitschriftenaufsatz | PUB-ID: 1587590
Perceiving molecular evolution processes in Escherichia coli by comprehensive metabolite and gene expression profiling
Vijayendran C, Barsch A, Friehs K, Niehaus K, Becker A, Flaschel E (2008)
GENOME BIOLOGY 9(4): R72.
PUB | PDF | DOI | WoS | PubMed | Europe PMC
 
[42]
2007 | Zeitschriftenaufsatz | PUB-ID: 1631667
2DBase: 2D-PAGE database of Escherichia coli
Vijayendran C, Burgemeister S, Friehs K, Niehaus K, Flaschel E (2007)
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 363(3): 822-827.
PUB | PDF | DOI | WoS | PubMed | Europe PMC
 
[41]
2007 | Zeitschriftenaufsatz | PUB-ID: 1594835
The plasticity of global proteome and genome expression analyzed in closely related W3110 and MG1655 strains of a well-studied model organism, Escherichia coli-K12
Vijayendran C, Polen T, Wendisch VF, Friehs K, Niehaus K, Flaschel E (2007)
Journal of Biotechnology 128(4): 747-761.
PUB | DOI | WoS | PubMed | Europe PMC
 
[40]
2007 | Zeitschriftenaufsatz | PUB-ID: 1593120 PUB | DOI | WoS | PubMed | Europe PMC
 
[39]
2007 | Zeitschriftenaufsatz | PUB-ID: 1595739
In situ dark field microscopy for on-line monitoring of yeast cultures
Wei N, You J, Friehs K, Flaschel E, Nattkemper TW (2007)
BIOTECHNOLOGY LETTERS 29(3): 373-378.
PUB | DOI | WoS | PubMed | Europe PMC
 
[38]
2007 | Zeitschriftenaufsatz | PUB-ID: 1593482
Improved beta-glucanase production by a recombinant Escherichia coli strain using a zinc-ion supplemented medium
Beshay U, Miksch G, Friehs K, Flaschel E (2007)
ENGINEERING IN LIFE SCIENCES 7(3): 253-258.
PUB | DOI | WoS
 
[37]
2007 | Zeitschriftenaufsatz | PUB-ID: 1631107
Recycling of bacterial biomass in a process of L-threonine production by means of a recombinant strain of Escherichia coli
Blaesen M, Friehs K, Flaschel E (2007)
JOURNAL OF BIOTECHNOLOGY 132(4): 431-437.
PUB | DOI | WoS | PubMed | Europe PMC
 
[36]
2007 | Zeitschriftenaufsatz | PUB-ID: 1631661 PUB | DOI | WoS | PubMed | Europe PMC
 
[35]
2006 | Zeitschriftenaufsatz | PUB-ID: 1600329
A rapid reporter system using GFP as a reporter protein for identification and screening of synthetic stationary-phase promoters in Escherichia coli
Miksch G, Bettenworth F, Friehs K, Flaschel E, Saalbach A, Nattkemper TW (2006)
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 70(2): 229-236.
PUB | DOI | WoS | PubMed | Europe PMC
 
[34]
2006 | Zeitschriftenaufsatz | PUB-ID: 1597472
Sustainable production: Recycling of bacterial biomass resulting from a fermentation process with Klebsiella planticola
Blaesen M, Flaschel E, Friehs K (2006)
CHEMICAL AND BIOCHEMICAL ENGINEERING QUARTERLY 20(3): 263-268.
PUB | WoS
 
[33]
2005 | Kurzbeitrag Konferenz | PUB-ID: 2906664
The plasticity of global proteome and genome expression analysis in a well studied closely related model organism, Escherichia coli
Polen T, Wendisch VF, Friehs K, Niehaus K, Flaschel E, Vijayendran C (2005)
MOLECULAR & CELLULAR PROTEOMICS 4(8): S248-S248.
PUB | WoS
 
[32]
2005 | Zeitschriftenaufsatz | PUB-ID: 1604386
A feedforward-feedback substrate controller based on a Kalman filter for a fed-batch cultivation of Escherichia coli producing phytase
Arndt M, Kleist S, Miksch G, Friehs K, Flaschel E, Trierweiler J, Hitzmann B (2005)
COMPUTERS & CHEMICAL ENGINEERING 29(5): 1113-1120.
PUB | DOI | WoS
 
[31]
2005 | Zeitschriftenaufsatz | PUB-ID: 1601074
The sequence upstream of the -10 consensus sequence modulates the strength and induction time of stationary-phase promoters in Escherichia coli
Miksch G, Bettenworth F, Friehs K, Flaschel E (2005)
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 69(3): 312-320.
PUB | DOI | WoS | PubMed | Europe PMC
 
[30]
2005 | Konferenzbeitrag | PUB-ID: 1601848
Libraries of synthetic stationary-phase and stress promoters as a tool for fine-tuning of expression of recombinant proteins in Escherichia coli
Miksch G, Bettenworth F, Friehs K, Flaschel E, Saalbach A, Twellmann T, Nattkemper TW (2005)
JOURNAL OF BIOTECHNOLOGY 120(1): 25-37.
PUB | DOI | WoS | PubMed | Europe PMC
 
[29]
2005 | Kurzbeitrag Konferenz | PUB-ID: 1601124
The plasticity of global proteome and genome expression analysis in a well studied closely related model organism, Escherichia coli
Vijayendran C, Polen T, Wendisch V, Friehs K, Niehaus K, Flaschel E (2005)
Molecular & Cellular Proteomics 4(8: Suppl. 1): S248.
PUB | WoS
 
[28]
2004 | Zeitschriftenaufsatz | PUB-ID: 1608845
Cultivation of Dictyostelium discoideum on an improved synthetic medium in a conventional bioreactor
Han SI, Friehs K, Flaschel E (2004)
PROCESS BIOCHEMISTRY 39(5): 585-589.
PUB | DOI | WoS
 
[27]
2004 | Zeitschriftenaufsatz | PUB-ID: 1607969
Improvement of a synthetic medium for Dictyostelium discoideum
Han SI, Friehs K, Flaschel E (2004)
PROCESS BIOCHEMISTRY 39(8): 925-930.
PUB | DOI | WoS
 
[26]
2004 | Zeitschriftenaufsatz | PUB-ID: 1608382
Production of the soluble human Fas ligand by Dictyostelium discoideum cultivated on a synthetic medium
Lu YH, Knol JC, Linskens MHK, Friehs K, van Haastert PJM, Flaschel E (2004)
JOURNAL OF BIOTECHNOLOGY 108(3): 243-251.
PUB | DOI | WoS | PubMed | Europe PMC
 
[25]
2004 | Zeitschriftenaufsatz | PUB-ID: 1609051
Effect of ammonium chloride on plasmid DNA production in high cell density batch culture for biopharmaceutical use
Voß C, Schmidt T, Schleef M, Friehs K, Flaschel E (2004)
JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY 79(1): 57-62.
PUB | DOI | WoS
 
[24]
2004 | Zeitschriftenaufsatz | PUB-ID: 1606278
Cultivation of immobilized Dictyostelium discoideum for the production of soluble human Fas ligand
Lu YH, Knol JC, Linskens MHK, Friehs K, van Haastert PJM, Flaschel E (2004)
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 65(5): 547-552.
PUB | DOI | WoS | PubMed | Europe PMC
 
[23]
2004 | Zeitschriftenaufsatz | PUB-ID: 1606443
Mass production of Dictyostelium discoideum in homogenous and hetergeneous cultivation systems
Lu YH, Beshay U, Friehs K, Flaschel E (2004)
PROCESS BIOCHEMISTRY 39(12): 1859-1870.
PUB | DOI | WoS
 
[22]
2003 | Zeitschriftenaufsatz | PUB-ID: 1609437
Analysis of the behaviour of Dictyostelium discoideum in immobilised state by means of continuous cultivation
Beshay U, Friehs K, Azzam AEM, Flaschel E (2003)
BIOPROCESS AND BIOSYSTEMS ENGINEERING 26(2): 117-122.
PUB | DOI | WoS | PubMed | Europe PMC
 
[21]
2003 | Zeitschriftenaufsatz | PUB-ID: 1610824
Cultivation of Dictyostelium discoideum in immobilized form by colonization of porous supports
Beshay U, Friehs K, Azzam AEM, Flaschel E (2003)
PROCESS BIOCHEMISTRY 38(11): 1521-1529.
PUB | DOI | WoS
 
[20]
2003 | Zeitschriftenaufsatz | PUB-ID: 1609656
Production of supercoiled multimeric plasmid DNA for biopharmaceutical application
Voß C, Schmidt T, Schleef M, Friehs K, Flaschel E (2003)
JOURNAL OF BIOTECHNOLOGY 105(3): 205-213.
PUB | DOI | WoS | PubMed | Europe PMC
 
[19]
2003 | Zeitschriftenaufsatz | PUB-ID: 1609485
Influence of medium composition on growth behaviour of Dictyostelium discoideum for cultivation on axenic media
Stephan M, Beshay U, Friehs K, Flaschel E (2003)
PROCESS BIOCHEMISTRY 39(3): 333-343.
PUB | DOI | WoS
 
[18]
2002 | Zeitschriftenaufsatz | PUB-ID: 1880734
Herstellung von Mediumskomponenten aus mikrobieller Biomasse
Schierl F, Friehs K, Risse JM, Flaschel E (2002)
Freiberger Forschungshefte A 866: 112-124.
PUB
 
[17]
2002 | Zeitschriftenaufsatz | PUB-ID: 1613472
Overexpression of the phytase from Escherichia coli and its extracellular production in bioreactors
Miksch G, Kleist S, Friehs K, Flaschel E (2002)
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 59(6): 685-694.
PUB | DOI | WoS | PubMed | Europe PMC
 
[16]
2001 | Zeitschriftenaufsatz | PUB-ID: 1880242
Recycling of Biomass Resulting from Fermentation Processes with Bacillus licheniformis
Risse JM, Friehs K, Flaschel E (2001)
Chem. Eng. Technol. 24(10): 141-145.
PUB
 
[15]
2000 | Zeitschriftenaufsatz | PUB-ID: 1619389
Biomasserückführung am Beispiel Bacillus licheniformis
Risse JM, Friehs K, Flaschel E (2000)
CHEMIE INGENIEUR TECHNIK 72(7): 750-754.
PUB | DOI | WoS
 
[14]
1999 | Bielefelder E-Habilitation | PUB-ID: 2305466
Maßnahmen zur Verbesserung der Produktion von rekombinanten Proteinen und Plasmid-DNS
Friehs K (1999)
Bielefeld (Germany): Bielefeld University.
PUB | PDF
 
[13]
1999 | Zeitschriftenaufsatz | PUB-ID: 1621612
Quantitative analysis of plasmid forms by agarose and capillary gel electrophoresis
Schmidt T, Friehs K, Schleef M, Voß C, Flaschel E (1999)
ANALYTICAL BIOCHEMISTRY 274(2): 235-240.
PUB | DOI | WoS | PubMed | Europe PMC
 
[12]
1999 | Zeitschriftenaufsatz | PUB-ID: 1622862
High-level expression of a recombinant protein in Klebsiella planticola owing to induced secretion into the culture medium
Miksch G, Neitzel R, Friehs K, Flaschel E (1999)
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 51(5): 627-632.
PUB | DOI | WoS | PubMed | Europe PMC
 
[11]
1998 | Zeitschriftenaufsatz | PUB-ID: 1625697
Reprocessing of bacterial biomass for recycling as a medium component in fermentation processes
Friehs K, Schierl F, Flaschel E (1998)
CHEMIE INGENIEUR TECHNIK 70(4): 435-437.
PUB | DOI | WoS
 
[10]
1997 | Zeitschriftenaufsatz | PUB-ID: 1637759
Extracellular production of a hybrid beta-glucanase from Bacillus by Escherichia coli under different cultivation conditions in shaking cultures and bioreactors
Miksch G, Neitzel R, Fiedler E, Friehs K, Flaschel E (1997)
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 47(2): 120-126.
PUB | DOI | WoS | PubMed | Europe PMC
 
[9]
1997 | Zeitschriftenaufsatz | PUB-ID: 1627108
The green fluorescent protein is a versatile reporter for bioprocess monitoring
Poppenborg L, Friehs K, Flaschel E (1997)
JOURNAL OF BIOTECHNOLOGY 58(2): 79-88.
PUB | DOI | WoS | PubMed | Europe PMC
 
[8]
1996 | Zeitschriftenaufsatz | PUB-ID: 1628395
Rapid determination of plasmid copy number
Schmidt T, Friehs K, Flaschel E (1996)
JOURNAL OF BIOTECHNOLOGY 49(1-3): 219-229.
PUB | DOI | WoS | PubMed | Europe PMC
 
[7]
1996 | Kurzbeitrag Konferenz | PUB-ID: 1639656
Plasmid copy number as a process variable for fermentation control.
Schmidt T, Friehs K, Flaschel E (1996)
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 211: 191-BIOT.
PUB | WoS
 
[6]
1993 | Zeitschriftenaufsatz | PUB-ID: 1646173
Improvement of downstream processing of recombinant proteins by means of genetic engineering
Flaschel E, Friehs K (1993)
Biotechnology Advances 11(1): 31-77.
PUB | PDF | DOI | WoS | PubMed | Europe PMC
 
[5]
1993 | Sammelwerksbeitrag | PUB-ID: 1782559
Parameters influencing the productivity of recombinant E. coli cultivations
Reardon KF, Friehs K (1993)
In: Bioprocess design and control. Aarts R (Ed); Advances in biochemical engineering, biotechnology ; 48. Berlin [u.a.]: Springer: 53-77.
PUB | PDF | PubMed | Europe PMC
 
[4]
1991 | Zeitschriftenaufsatz | PUB-ID: 1782553
Strategies for improving plasmid stability in genetically modified bacteria in bioreactors
Kumar PKR, Maschke H-E, Friehs K, Schügerl K (1991)
Trends in biotechnology 9(1): 279-284.
PUB | PDF | DOI | WoS | PubMed | Europe PMC
 
[3]
1989 | Zeitschriftenaufsatz | PUB-ID: 1782550 PUB | PDF | DOI | WoS
 
[2]
1989 | Zeitschriftenaufsatz | PUB-ID: 1782547 PUB | PDF | DOI | WoS
 
[1]
1986 | Zeitschriftenaufsatz | PUB-ID: 1782542
Cloning and phenotypic expression in Escherichia coli of a Bacillus subtilis gene fragment coding for sucrose hydrolysis
Friehs K, Schörgendorfer K, Schwab H, Lafferty RM (1986)
Journal of Biotechnology 3(5-6): 333-341.
PUB | PDF | DOI | WoS
 

Suche

Publikationen filtern

Darstellung / Sortierung

Export / Einbettung

67 Publikationen

Alle markieren

[67]
2018 | Zeitschriftenaufsatz | PUB-ID: 2930505
Secretion of recombinant proteins from E. coli
Kleiner-Grote G, Risse JM, Friehs K (2018)
ENGINEERING IN LIFE SCIENCES 18(8): 532-550.
PUB | DOI | WoS
 
[66]
2017 | Zeitschriftenaufsatz | PUB-ID: 2916444
Towards systems metabolic engineering in Pichia pastoris
Schwarzhans JP, Luttermann T, Geier M, Kalinowski J, Friehs K (2017)
BIOTECHNOLOGY ADVANCES 35(6): 681-710.
PUB | DOI | WoS | PubMed | Europe PMC
 
[65]
2017 | Zeitschriftenaufsatz | PUB-ID: 2908307
Fermentative production of L-pipecolic acid from glucose and alternative carbon sources
Perez F, Risse JM, Friehs K, Wendisch VF (2017)
Biotechnology Journal 12(7): 1600646.
PUB | DOI | WoS | PubMed | Europe PMC
 
[64]
2017 | Zeitschriftenaufsatz | PUB-ID: 2910668
A Mitochondrial Autonomously Replicating Sequence from Pichia pastoris for Uniform High Level Recombinant Protein Production
Friehs K, Schwarzhans JP, Luttermann T, Wibberg D, Winkler A, Hübner W, Huser T, Kalinowski J (2017)
Frontiers in Microbiology 8: 780.
PUB | PDF | DOI | WoS | PubMed | Europe PMC
 
[63]
2016 | Zeitschriftenaufsatz | PUB-ID: 2907679
Non-canonical integration events in Pichia pastoris encountered during standard transformation analysed with genome sequencing
Schwarzhans JP, Wibberg D, Winkler A, Luttermann T, Kalinowski J, Friehs K (2016)
Scientific Reports 6: 38952.
PUB | PDF | DOI | WoS | PubMed | Europe PMC
 
[62]
2016 | Zeitschriftenaufsatz | PUB-ID: 2903655
Integration event induced changes in recombinant protein productivity in Pichia pastoris discovered by whole genome sequencing and derived vector optimization
Schwarzhans JP, Wibberg D, Winkler A, Luttermann T, Kalinowski J, Friehs K (2016)
Microbial Cell Factories 15: 84.
PUB | PDF | DOI | WoS | PubMed | Europe PMC
 
[61]
2016 | Zeitschriftenaufsatz | PUB-ID: 2903023
Fed-batch production and secretion of streptavidin by Hansenula polymorpha: Evaluation of genetic factors and bioprocess development
Wetzel D, Müller J, Flaschel E, Friehs K, Risse JM (2016)
JOURNAL OF BIOTECHNOLOGY 225: 3-9.
PUB | DOI | WoS | PubMed | Europe PMC
 
[60]
2016 | Zeitschriftenaufsatz | PUB-ID: 2906700
Effects of particle addition to Streptomyces cultivations to optimize the production of actinorhodin and streptavidin
Holtmann D, Vernen F, Müller J, Kaden D, Risse JM, Friehs K, Dähne L, Stratmann A, Schrader J (2016)
Sustainable Chemistry and Pharmacy.
PUB | DOI | WoS
 
[59]
2016 | Zeitschriftenaufsatz | PUB-ID: 2906197
GAP promoter-based fed-batch production of highly bioactive core streptavidin by Pichia pastoris
Müller J, Bruhn S, Flaschel E, Friehs K, Risse JM (2016)
BIOTECHNOLOGY PROGRESS 32(4): 855-864.
PUB | DOI | WoS | PubMed | Europe PMC
 
[58]
2016 | Zeitschriftenaufsatz | PUB-ID: 2900637
Constitutive production and efficient secretion of soluble full-length streptavidin by an Escherichia coli 'leaky mutant'
Müller J, Wetzel D, Flaschel E, Friehs K, Risse JM (2016)
Journal of Biotechnology 221: 91-100.
PUB | DOI | WoS | PubMed | Europe PMC
 
[57]
2015 | Zeitschriftenaufsatz | PUB-ID: 2767378
Model-based development of an assay for the rapid detection of biotin-blocked binding sites of streptavidin
Müller J, Risse JM, Friehs K, Flaschel E (2015)
Engineering in Life Sciences 15(6): 627-639.
PUB | DOI | WoS
 
[56]
2015 | Zeitschriftenaufsatz | PUB-ID: 2759080
Applicability of Euglena gracilis for biorefineries demonstrated by the production of α-tocopherol and paramylon followed by anaerobic digestion
Grimm P, Risse JM, Müller J, Cholewa D, Beshay U, Friehs K, Flaschel E (2015)
Journal of Biotechnology 215: 72-79.
PUB | DOI | WoS | PubMed | Europe PMC
 
[55]
2015 | Zeitschriftenaufsatz | PUB-ID: 2722001
Dependency of the fatty acid composition of Euglena gracilis on growth phase and culture conditions
Schwarzhans JP, Cholewa D, Grimm P, Beshay U, Risse JM, Friehs K, Flaschel E (2015)
Journal of Applied Phycology 27(4): 1389-1399.
PUB | DOI | WoS
 
[54]
2014 | Zeitschriftenaufsatz | PUB-ID: 2679910
Antibiotic-free segregational plasmid stabilization in Escherichia coli owing to the knockout of triosephosphate isomerase (tpiA)
Selvamani RSV, Telaar M, Friehs K, Flaschel E (2014)
Microbial Cell Factories 13: 58.
PUB | PDF | DOI | WoS | PubMed | Europe PMC
 
[53]
2014 | Zeitschriftenaufsatz | PUB-ID: 2675672 PUB | DOI | WoS | PubMed | Europe PMC
 
[52]
2012 | Zeitschriftenaufsatz | PUB-ID: 2474324 PUB | DOI | WoS
 
[51]
2010 | Zeitschriftenaufsatz | PUB-ID: 2401962
Sekretion und Affinitätschromatografie rekombinanter Proteine
Risse JM, Friehs K (2010)
BIOspektrum 5: 550-552.
PUB
 
[50]
2010 | Zeitschriftenaufsatz | PUB-ID: 1796536 PUB | DOI | WoS | PubMed | Europe PMC
 
[49]
2010 | Zeitschriftenaufsatz | PUB-ID: 1795042
Production of paramylon, a beta-1,3-glucan, by heterotrophic cultivation of Euglena gracilis on potato liquor
Santek B, Felski M, Friehs K, Lotz M, Flaschel E (2010)
ENGINEERING IN LIFE SCIENCES 10(2): NA.
PUB | DOI | WoS
 
[48]
2009 | Zeitschriftenaufsatz | PUB-ID: 1635287
Production of paramylon, a beta-1,3-glucan, by heterotrophic cultivation of Euglena gracilis on a synthetic medium
Santek B, Felski M, Friehs K, Lotz M, Flaschel E (2009)
ENGINEERING IN LIFE SCIENCES 9(1): 23-28.
PUB | DOI | WoS
 
[47]
2009 | Zeitschriftenaufsatz | PUB-ID: 1634165
Extracellular production and affinity purification of recombinant proteins with Escherichia coli using the versatility of the maltose binding protein
Sommer B, Friehs K, Flaschel E, Reck M, Stahl F, Scheper T (2009)
JOURNAL OF BIOTECHNOLOGY 140(3-4): 194-202.
PUB | DOI | WoS | PubMed | Europe PMC
 
[46]
2009 | Zeitschriftenaufsatz | PUB-ID: 1636091
Integrated bioprocess for the production and purification of recombinant proteins by affinity chromatography in Escherichia coli
Beshay U, Miksch G, Friehs K, Flaschel E (2009)
BIOPROCESS AND BIOSYSTEMS ENGINEERING 32(2): 149-158.
PUB | DOI | WoS | PubMed | Europe PMC
 
[45]
2008 | Zeitschriftenaufsatz | PUB-ID: 1585399 PUB | DOI | WoS
 
[44]
2008 | Zeitschriftenaufsatz | PUB-ID: 1585611 PUB | PDF | DOI | WoS | PubMed | Europe PMC
 
[43]
2008 | Zeitschriftenaufsatz | PUB-ID: 1587590
Perceiving molecular evolution processes in Escherichia coli by comprehensive metabolite and gene expression profiling
Vijayendran C, Barsch A, Friehs K, Niehaus K, Becker A, Flaschel E (2008)
GENOME BIOLOGY 9(4): R72.
PUB | PDF | DOI | WoS | PubMed | Europe PMC
 
[42]
2007 | Zeitschriftenaufsatz | PUB-ID: 1631667
2DBase: 2D-PAGE database of Escherichia coli
Vijayendran C, Burgemeister S, Friehs K, Niehaus K, Flaschel E (2007)
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 363(3): 822-827.
PUB | PDF | DOI | WoS | PubMed | Europe PMC
 
[41]
2007 | Zeitschriftenaufsatz | PUB-ID: 1594835
The plasticity of global proteome and genome expression analyzed in closely related W3110 and MG1655 strains of a well-studied model organism, Escherichia coli-K12
Vijayendran C, Polen T, Wendisch VF, Friehs K, Niehaus K, Flaschel E (2007)
Journal of Biotechnology 128(4): 747-761.
PUB | DOI | WoS | PubMed | Europe PMC
 
[40]
2007 | Zeitschriftenaufsatz | PUB-ID: 1593120 PUB | DOI | WoS | PubMed | Europe PMC
 
[39]
2007 | Zeitschriftenaufsatz | PUB-ID: 1595739
In situ dark field microscopy for on-line monitoring of yeast cultures
Wei N, You J, Friehs K, Flaschel E, Nattkemper TW (2007)
BIOTECHNOLOGY LETTERS 29(3): 373-378.
PUB | DOI | WoS | PubMed | Europe PMC
 
[38]
2007 | Zeitschriftenaufsatz | PUB-ID: 1593482
Improved beta-glucanase production by a recombinant Escherichia coli strain using a zinc-ion supplemented medium
Beshay U, Miksch G, Friehs K, Flaschel E (2007)
ENGINEERING IN LIFE SCIENCES 7(3): 253-258.
PUB | DOI | WoS
 
[37]
2007 | Zeitschriftenaufsatz | PUB-ID: 1631107
Recycling of bacterial biomass in a process of L-threonine production by means of a recombinant strain of Escherichia coli
Blaesen M, Friehs K, Flaschel E (2007)
JOURNAL OF BIOTECHNOLOGY 132(4): 431-437.
PUB | DOI | WoS | PubMed | Europe PMC
 
[36]
2007 | Zeitschriftenaufsatz | PUB-ID: 1631661 PUB | DOI | WoS | PubMed | Europe PMC
 
[35]
2006 | Zeitschriftenaufsatz | PUB-ID: 1600329
A rapid reporter system using GFP as a reporter protein for identification and screening of synthetic stationary-phase promoters in Escherichia coli
Miksch G, Bettenworth F, Friehs K, Flaschel E, Saalbach A, Nattkemper TW (2006)
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 70(2): 229-236.
PUB | DOI | WoS | PubMed | Europe PMC
 
[34]
2006 | Zeitschriftenaufsatz | PUB-ID: 1597472
Sustainable production: Recycling of bacterial biomass resulting from a fermentation process with Klebsiella planticola
Blaesen M, Flaschel E, Friehs K (2006)
CHEMICAL AND BIOCHEMICAL ENGINEERING QUARTERLY 20(3): 263-268.
PUB | WoS
 
[33]
2005 | Kurzbeitrag Konferenz | PUB-ID: 2906664
The plasticity of global proteome and genome expression analysis in a well studied closely related model organism, Escherichia coli
Polen T, Wendisch VF, Friehs K, Niehaus K, Flaschel E, Vijayendran C (2005)
MOLECULAR & CELLULAR PROTEOMICS 4(8): S248-S248.
PUB | WoS
 
[32]
2005 | Zeitschriftenaufsatz | PUB-ID: 1604386
A feedforward-feedback substrate controller based on a Kalman filter for a fed-batch cultivation of Escherichia coli producing phytase
Arndt M, Kleist S, Miksch G, Friehs K, Flaschel E, Trierweiler J, Hitzmann B (2005)
COMPUTERS & CHEMICAL ENGINEERING 29(5): 1113-1120.
PUB | DOI | WoS
 
[31]
2005 | Zeitschriftenaufsatz | PUB-ID: 1601074
The sequence upstream of the -10 consensus sequence modulates the strength and induction time of stationary-phase promoters in Escherichia coli
Miksch G, Bettenworth F, Friehs K, Flaschel E (2005)
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 69(3): 312-320.
PUB | DOI | WoS | PubMed | Europe PMC
 
[30]
2005 | Konferenzbeitrag | PUB-ID: 1601848
Libraries of synthetic stationary-phase and stress promoters as a tool for fine-tuning of expression of recombinant proteins in Escherichia coli
Miksch G, Bettenworth F, Friehs K, Flaschel E, Saalbach A, Twellmann T, Nattkemper TW (2005)
JOURNAL OF BIOTECHNOLOGY 120(1): 25-37.
PUB | DOI | WoS | PubMed | Europe PMC
 
[29]
2005 | Kurzbeitrag Konferenz | PUB-ID: 1601124
The plasticity of global proteome and genome expression analysis in a well studied closely related model organism, Escherichia coli
Vijayendran C, Polen T, Wendisch V, Friehs K, Niehaus K, Flaschel E (2005)
Molecular & Cellular Proteomics 4(8: Suppl. 1): S248.
PUB | WoS
 
[28]
2004 | Zeitschriftenaufsatz | PUB-ID: 1608845
Cultivation of Dictyostelium discoideum on an improved synthetic medium in a conventional bioreactor
Han SI, Friehs K, Flaschel E (2004)
PROCESS BIOCHEMISTRY 39(5): 585-589.
PUB | DOI | WoS
 
[27]
2004 | Zeitschriftenaufsatz | PUB-ID: 1607969
Improvement of a synthetic medium for Dictyostelium discoideum
Han SI, Friehs K, Flaschel E (2004)
PROCESS BIOCHEMISTRY 39(8): 925-930.
PUB | DOI | WoS
 
[26]
2004 | Zeitschriftenaufsatz | PUB-ID: 1608382
Production of the soluble human Fas ligand by Dictyostelium discoideum cultivated on a synthetic medium
Lu YH, Knol JC, Linskens MHK, Friehs K, van Haastert PJM, Flaschel E (2004)
JOURNAL OF BIOTECHNOLOGY 108(3): 243-251.
PUB | DOI | WoS | PubMed | Europe PMC
 
[25]
2004 | Zeitschriftenaufsatz | PUB-ID: 1609051
Effect of ammonium chloride on plasmid DNA production in high cell density batch culture for biopharmaceutical use
Voß C, Schmidt T, Schleef M, Friehs K, Flaschel E (2004)
JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY 79(1): 57-62.
PUB | DOI | WoS
 
[24]
2004 | Zeitschriftenaufsatz | PUB-ID: 1606278
Cultivation of immobilized Dictyostelium discoideum for the production of soluble human Fas ligand
Lu YH, Knol JC, Linskens MHK, Friehs K, van Haastert PJM, Flaschel E (2004)
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 65(5): 547-552.
PUB | DOI | WoS | PubMed | Europe PMC
 
[23]
2004 | Zeitschriftenaufsatz | PUB-ID: 1606443
Mass production of Dictyostelium discoideum in homogenous and hetergeneous cultivation systems
Lu YH, Beshay U, Friehs K, Flaschel E (2004)
PROCESS BIOCHEMISTRY 39(12): 1859-1870.
PUB | DOI | WoS
 
[22]
2003 | Zeitschriftenaufsatz | PUB-ID: 1609437
Analysis of the behaviour of Dictyostelium discoideum in immobilised state by means of continuous cultivation
Beshay U, Friehs K, Azzam AEM, Flaschel E (2003)
BIOPROCESS AND BIOSYSTEMS ENGINEERING 26(2): 117-122.
PUB | DOI | WoS | PubMed | Europe PMC
 
[21]
2003 | Zeitschriftenaufsatz | PUB-ID: 1610824
Cultivation of Dictyostelium discoideum in immobilized form by colonization of porous supports
Beshay U, Friehs K, Azzam AEM, Flaschel E (2003)
PROCESS BIOCHEMISTRY 38(11): 1521-1529.
PUB | DOI | WoS
 
[20]
2003 | Zeitschriftenaufsatz | PUB-ID: 1609656
Production of supercoiled multimeric plasmid DNA for biopharmaceutical application
Voß C, Schmidt T, Schleef M, Friehs K, Flaschel E (2003)
JOURNAL OF BIOTECHNOLOGY 105(3): 205-213.
PUB | DOI | WoS | PubMed | Europe PMC
 
[19]
2003 | Zeitschriftenaufsatz | PUB-ID: 1609485
Influence of medium composition on growth behaviour of Dictyostelium discoideum for cultivation on axenic media
Stephan M, Beshay U, Friehs K, Flaschel E (2003)
PROCESS BIOCHEMISTRY 39(3): 333-343.
PUB | DOI | WoS
 
[18]
2002 | Zeitschriftenaufsatz | PUB-ID: 1880734
Herstellung von Mediumskomponenten aus mikrobieller Biomasse
Schierl F, Friehs K, Risse JM, Flaschel E (2002)
Freiberger Forschungshefte A 866: 112-124.
PUB
 
[17]
2002 | Zeitschriftenaufsatz | PUB-ID: 1613472
Overexpression of the phytase from Escherichia coli and its extracellular production in bioreactors
Miksch G, Kleist S, Friehs K, Flaschel E (2002)
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 59(6): 685-694.
PUB | DOI | WoS | PubMed | Europe PMC
 
[16]
2001 | Zeitschriftenaufsatz | PUB-ID: 1880242
Recycling of Biomass Resulting from Fermentation Processes with Bacillus licheniformis
Risse JM, Friehs K, Flaschel E (2001)
Chem. Eng. Technol. 24(10): 141-145.
PUB
 
[15]
2000 | Zeitschriftenaufsatz | PUB-ID: 1619389
Biomasserückführung am Beispiel Bacillus licheniformis
Risse JM, Friehs K, Flaschel E (2000)
CHEMIE INGENIEUR TECHNIK 72(7): 750-754.
PUB | DOI | WoS
 
[14]
1999 | Bielefelder E-Habilitation | PUB-ID: 2305466
Maßnahmen zur Verbesserung der Produktion von rekombinanten Proteinen und Plasmid-DNS
Friehs K (1999)
Bielefeld (Germany): Bielefeld University.
PUB | PDF
 
[13]
1999 | Zeitschriftenaufsatz | PUB-ID: 1621612
Quantitative analysis of plasmid forms by agarose and capillary gel electrophoresis
Schmidt T, Friehs K, Schleef M, Voß C, Flaschel E (1999)
ANALYTICAL BIOCHEMISTRY 274(2): 235-240.
PUB | DOI | WoS | PubMed | Europe PMC
 
[12]
1999 | Zeitschriftenaufsatz | PUB-ID: 1622862
High-level expression of a recombinant protein in Klebsiella planticola owing to induced secretion into the culture medium
Miksch G, Neitzel R, Friehs K, Flaschel E (1999)
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 51(5): 627-632.
PUB | DOI | WoS | PubMed | Europe PMC
 
[11]
1998 | Zeitschriftenaufsatz | PUB-ID: 1625697
Reprocessing of bacterial biomass for recycling as a medium component in fermentation processes
Friehs K, Schierl F, Flaschel E (1998)
CHEMIE INGENIEUR TECHNIK 70(4): 435-437.
PUB | DOI | WoS
 
[10]
1997 | Zeitschriftenaufsatz | PUB-ID: 1637759
Extracellular production of a hybrid beta-glucanase from Bacillus by Escherichia coli under different cultivation conditions in shaking cultures and bioreactors
Miksch G, Neitzel R, Fiedler E, Friehs K, Flaschel E (1997)
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 47(2): 120-126.
PUB | DOI | WoS | PubMed | Europe PMC
 
[9]
1997 | Zeitschriftenaufsatz | PUB-ID: 1627108
The green fluorescent protein is a versatile reporter for bioprocess monitoring
Poppenborg L, Friehs K, Flaschel E (1997)
JOURNAL OF BIOTECHNOLOGY 58(2): 79-88.
PUB | DOI | WoS | PubMed | Europe PMC
 
[8]
1996 | Zeitschriftenaufsatz | PUB-ID: 1628395
Rapid determination of plasmid copy number
Schmidt T, Friehs K, Flaschel E (1996)
JOURNAL OF BIOTECHNOLOGY 49(1-3): 219-229.
PUB | DOI | WoS | PubMed | Europe PMC
 
[7]
1996 | Kurzbeitrag Konferenz | PUB-ID: 1639656
Plasmid copy number as a process variable for fermentation control.
Schmidt T, Friehs K, Flaschel E (1996)
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 211: 191-BIOT.
PUB | WoS
 
[6]
1993 | Zeitschriftenaufsatz | PUB-ID: 1646173
Improvement of downstream processing of recombinant proteins by means of genetic engineering
Flaschel E, Friehs K (1993)
Biotechnology Advances 11(1): 31-77.
PUB | PDF | DOI | WoS | PubMed | Europe PMC
 
[5]
1993 | Sammelwerksbeitrag | PUB-ID: 1782559
Parameters influencing the productivity of recombinant E. coli cultivations
Reardon KF, Friehs K (1993)
In: Bioprocess design and control. Aarts R (Ed); Advances in biochemical engineering, biotechnology ; 48. Berlin [u.a.]: Springer: 53-77.
PUB | PDF | PubMed | Europe PMC
 
[4]
1991 | Zeitschriftenaufsatz | PUB-ID: 1782553
Strategies for improving plasmid stability in genetically modified bacteria in bioreactors
Kumar PKR, Maschke H-E, Friehs K, Schügerl K (1991)
Trends in biotechnology 9(1): 279-284.
PUB | PDF | DOI | WoS | PubMed | Europe PMC
 
[3]
1989 | Zeitschriftenaufsatz | PUB-ID: 1782550 PUB | PDF | DOI | WoS
 
[2]
1989 | Zeitschriftenaufsatz | PUB-ID: 1782547 PUB | PDF | DOI | WoS
 
[1]
1986 | Zeitschriftenaufsatz | PUB-ID: 1782542
Cloning and phenotypic expression in Escherichia coli of a Bacillus subtilis gene fragment coding for sucrose hydrolysis
Friehs K, Schörgendorfer K, Schwab H, Lafferty RM (1986)
Journal of Biotechnology 3(5-6): 333-341.
PUB | PDF | DOI | WoS
 

Suche

Publikationen filtern

Darstellung / Sortierung

Export / Einbettung