Erwin Flaschel
PEVZ-ID
93 Publikationen
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2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2904075Müller J, Risse JM, Jussen D, Flaschel E (2016)PUB | DOI | WoS | PubMed | Europe PMC
Development of fed-batch strategies for the production of streptavidin by Streptomyces avidinii based on power input and oxygen supply studies (vol 163, pg 325, 2013).
JOURNAL OF BIOTECHNOLOGY 226: 76-77. -
2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2906183Schulte F, Flaschel E, Niehaus K (2016)PUB | DOI | WoS | PubMed | Europe PMC
Proteome-Based Analysis of Colloidal Instability Enables the Detection of Haze-Active Proteins in Beer.
Journal of Agricultural and Food Chemistry 64(35): 6752-6761. -
2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2903023Wetzel D, Müller J, Flaschel E, Friehs K, Risse JM (2016)PUB | DOI | WoS | PubMed | Europe PMC
Fed-batch production and secretion of streptavidin by Hansenula polymorpha: Evaluation of genetic factors and bioprocess development.
JOURNAL OF BIOTECHNOLOGY 225: 3-9. -
2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2906197Müller J, Bruhn S, Flaschel E, Friehs K, Risse JM (2016)PUB | DOI | WoS | PubMed | Europe PMC
GAP promoter-based fed-batch production of highly bioactive core streptavidin by Pichia pastoris.
BIOTECHNOLOGY PROGRESS 32(4): 855-864. -
2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2900637Müller J, Wetzel D, Flaschel E, Friehs K, Risse JM (2016)PUB | DOI | WoS | PubMed | Europe PMC
Constitutive production and efficient secretion of soluble full-length streptavidin by an Escherichia coli 'leaky mutant'.
Journal of Biotechnology 221: 91-100. -
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2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2759080Grimm P, Risse JM, Müller J, Cholewa D, Beshay U, Friehs K, Flaschel E (2015)PUB | DOI | WoS | PubMed | Europe PMC
Applicability of Euglena gracilis for biorefineries demonstrated by the production of α-tocopherol and paramylon followed by anaerobic digestion.
Journal of Biotechnology 215: 72-79. -
2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2722001Schwarzhans JP, Cholewa D, Grimm P, Beshay U, Risse JM, Friehs K, Flaschel E (2015)PUB | DOI | WoS
Dependency of the fatty acid composition of Euglena gracilis on growth phase and culture conditions.
Journal of Applied Phycology 27(4): 1389-1399. -
2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2679910Selvamani RSV, Telaar M, Friehs K, Flaschel E (2014)PUB | PDF | DOI | WoS | PubMed | Europe PMC
Antibiotic-free segregational plasmid stabilization in Escherichia coli owing to the knockout of triosephosphate isomerase (tpiA).
Microbial Cell Factories 13(1): 58. -
2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2675672Selvamani RSV, Friehs K, Flaschel E (2014)PUB | DOI | WoS | PubMed | Europe PMC
Extracellular recombinant protein production under continuous culture conditions with Escherichia coli using an alternative plasmid selection mechanism.
Bioprocess and Biosystems Engineering 37(3): 401-413. -
2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2551139Müller JM, Risse JM, Jussen D, Flaschel E (2013)PUB | DOI | WoS | PubMed | Europe PMC
Development of fed-batch strategies for the production of streptavidin by Streptomyces avidinii based on power input and oxygen supply studies.
Journal of Biotechnology 163(3): 325-332. -
2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1945165Vijayendran C, Flaschel E (2010)PUB | DOI | WoS | PubMed | Europe PMC
Impact of profiling technologies in the understanding of recombinant protein production.
Adv Biochem Eng Biotechnol 121: 45-70. -
2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1929340Burgemeister S, Nattkemper TW, Noll T, Hoffrogge R, Flaschel E (2010)PUB | DOI | WoS | PubMed | Europe PMC
CellViCAM-Cell viability classification for animal cell cultures using dark field micrographs.
JOURNAL OF BIOTECHNOLOGY 149(4): 310-316. -
2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1796536Sommer B, Friehs K, Flaschel E (2010)PUB | DOI | WoS | PubMed | Europe PMC
Efficient production of extracellular proteins with Escherichia coli by means of optimized coexpression of bacteriocin release proteins.
JOURNAL OF BIOTECHNOLOGY 145(4): 350-358. -
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2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1588919Spexard M, Beshay U, Risse JM, Miksch G, Flaschel E (2010)PUB | DOI | WoS | PubMed | Europe PMC
Screening for conditions of enhanced production of a recombinant beta-glucanase secreted into the medium by Escherichia coli.
BIOTECHNOLOGY LETTERS 32(2): 243-248. -
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2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1591533Tschapalda K, Streitner N, Voß C, Flaschel E (2009)PUB | DOI | WoS | PubMed | Europe PMC
Generation of chromosomal DNA during alkaline lysis and removal by reverse micellar extraction.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 84(1): 199-204. -
2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1636091Beshay U, Miksch G, Friehs K, Flaschel E (2009)PUB | DOI | WoS | PubMed | Europe PMC
Integrated bioprocess for the production and purification of recombinant proteins by affinity chromatography in Escherichia coli.
BIOPROCESS AND BIOSYSTEMS ENGINEERING 32(2): 149-158. -
2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1634165Sommer B, Friehs K, Flaschel E, Reck M, Stahl F, Scheper T (2009)PUB | DOI | WoS | PubMed | Europe PMC
Extracellular production and affinity purification of recombinant proteins with Escherichia coli using the versatility of the maltose binding protein.
JOURNAL OF BIOTECHNOLOGY 140(3-4): 194-202. -
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2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1585611Wei N, Flaschel E, Friehs K, Nattkemper TW (2008)PUB | PDF | DOI | WoS | PubMed | Europe PMC
A machine vision system for automated non-invasive assessment of cell viability via dark field microscopy, wavelet feature selection and classification.
BMC Bioinformatics 9(1): 449. -
2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1587590Vijayendran C, Barsch A, Friehs K, Niehaus K, Becker A, Flaschel E (2008)PUB | PDF | DOI | WoS | PubMed | Europe PMC
Perceiving molecular evolution processes in Escherichia coli by comprehensive metabolite and gene expression profiling.
GENOME BIOLOGY 9(4): R72. -
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2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1585617Miksch G, Ryu S, Risse JM, Flaschel E (2008)PUB | DOI | WoS | PubMed | Europe PMC
Factors that influence the extracellular expression of streptavidin in Escherichia coli using a bacteriocin release protein.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 81(2): 319-326. -
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2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1594835Vijayendran C, Polen T, Wendisch VF, Friehs K, Niehaus K, Flaschel E (2007)PUB | DOI | WoS | PubMed | Europe PMC
The plasticity of global proteome and genome expression analyzed in closely related W3110 and MG1655 strains of a well-studied model organism, Escherichia coli-K12.
Journal of Biotechnology 128(4): 747-761. -
2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1595739Wei N, You J, Friehs K, Flaschel E, Nattkemper TW (2007)PUB | DOI | WoS | PubMed | Europe PMC
In situ dark field microscopy for on-line monitoring of yeast cultures.
BIOTECHNOLOGY LETTERS 29(3): 373-378. -
2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1593120Wei N, You J, Friehs K, Flaschel E, Nattkemper TW (2007)PUB | DOI | WoS | PubMed | Europe PMC
An in situ probe for on-line monitoring of cell density and viability on the basis of dark field microscopy in conjunction with image processing and supervised machine learning.
Biotechnology and Bioengineering 97(6): 1489-1500. -
2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1632656Streitner N, Voß C, Flaschel E (2007)PUB | DOI | WoS | PubMed | Europe PMC
Reverse micellar extraction systems for the purification of pharmaceutical grade plasmid DNA.
JOURNAL OF BIOTECHNOLOGY 131(2): 188-196. -
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2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1593326Beshay U, Miksch G, Flaschel E (2007)PUB | DOI | WoS | PubMed | Europe PMC
Improvement of a beta-glucanase activity test by taking into account the batch reactor balance of the test system.
BIOPROCESS AND BIOSYSTEMS ENGINEERING 30(4): 251-259. -
2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1631107Blaesen M, Friehs K, Flaschel E (2007)PUB | DOI | WoS | PubMed | Europe PMC
Recycling of bacterial biomass in a process of L-threonine production by means of a recombinant strain of Escherichia coli.
JOURNAL OF BIOTECHNOLOGY 132(4): 431-437. -
2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1631661Beshay U, Miksch G, Friehs K, Flaschel E (2007)PUB | DOI | WoS | PubMed | Europe PMC
Increasing the secretion ability of the kil gene for recombinant proteins in Escherichia coli by using a strong stationary-phase promoter.
BIOTECHNOLOGY LETTERS 29(12): 1893-1901. -
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2006 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1600329Miksch G, Bettenworth F, Friehs K, Flaschel E, Saalbach A, Nattkemper TW (2006)PUB | DOI | WoS | PubMed | Europe PMC
A rapid reporter system using GFP as a reporter protein for identification and screening of synthetic stationary-phase promoters in Escherichia coli.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 70(2): 229-236. -
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2006 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1599112Voß C, Lindau D, Flaschel E (2006)PUB | DOI | WoS | PubMed | Europe PMC
Production of recombinant RNase Ba and its application in downstream processing of plasmid DNA for pharmaceutical use.
BIOTECHNOLOGY PROGRESS 22(3): 737-744. -
2005 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2906664Polen T, Wendisch VF, Friehs K, Niehaus K, Flaschel E, Vijayendran C (2005)PUB | WoS
The plasticity of global proteome and genome expression analysis in a well studied closely related model organism, Escherichia coli.
MOLECULAR & CELLULAR PROTEOMICS 4(8): S248-S248. -
2005 | Monographie | PUB-ID: 2714309Bettenworth F, Miksch G, Fries K, Flaschel E, Saalbach A, Eickmeyer J, Nattkemper TW (2005)PUB
An Online Monitoring System for the Screening of Stationary-Phase Promoters in E. Coli using GFP as a Reporter Protein. -
2005 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1604386Arndt M, Kleist S, Miksch G, Friehs K, Flaschel E, Trierweiler J, Hitzmann B (2005)PUB | DOI | WoS
A feedforward-feedback substrate controller based on a Kalman filter for a fed-batch cultivation of Escherichia coli producing phytase.
COMPUTERS & CHEMICAL ENGINEERING 29(5): 1113-1120. -
2005 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1946602Wei N, Flaschel E, Saalbach A, Twellmann T, Nattkemper TW (2005)PUB | DOI | PubMed | Europe PMC
Reagent-free automatic cell viability determination using neural networks based machine vision and dark-field microscopy in Saccharomyces cerevisiae.
Conf Proc IEEE Eng Med Biol Soc 6: 6305-6308. -
2005 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1601074Miksch G, Bettenworth F, Friehs K, Flaschel E (2005)PUB | DOI | WoS | PubMed | Europe PMC
The sequence upstream of the -10 consensus sequence modulates the strength and induction time of stationary-phase promoters in Escherichia coli.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 69(3): 312-320. -
2005 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 1601848Miksch G, Bettenworth F, Friehs K, Flaschel E, Saalbach A, Twellmann T, Nattkemper TW (2005)PUB | DOI | WoS | PubMed | Europe PMC
Libraries of synthetic stationary-phase and stress promoters as a tool for fine-tuning of expression of recombinant proteins in Escherichia coli.
In: Journal of Biotechnology. JOURNAL OF BIOTECHNOLOGY, 120. ELSEVIER SCIENCE BV: 25-37. -
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2005 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 1601124Vijayendran C, Polen T, Wendisch V, Friehs K, Niehaus K, Flaschel E (2005)PUB | WoS
The plasticity of global proteome and genome expression analysis in a well studied closely related model organism, Escherichia coli.
Molecular & Cellular Proteomics 4(8: Suppl. 1): S248. -
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2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1609051Voß C, Schmidt T, Schleef M, Friehs K, Flaschel E (2004)PUB | DOI | WoS
Effect of ammonium chloride on plasmid DNA production in high cell density batch culture for biopharmaceutical use.
JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY 79(1): 57-62. -
2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1608382Lu YH, Knol JC, Linskens MHK, Friehs K, van Haastert PJM, Flaschel E (2004)PUB | DOI | WoS | PubMed | Europe PMC
Production of the soluble human Fas ligand by Dictyostelium discoideum cultivated on a synthetic medium.
JOURNAL OF BIOTECHNOLOGY 108(3): 243-251. -
2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1606278Lu YH, Knol JC, Linskens MHK, Friehs K, van Haastert PJM, Flaschel E (2004)PUB | DOI | WoS | PubMed | Europe PMC
Cultivation of immobilized Dictyostelium discoideum for the production of soluble human Fas ligand.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 65(5): 547-552. -
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2003 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1609437Beshay U, Friehs K, Azzam AEM, Flaschel E (2003)PUB | DOI | WoS | PubMed | Europe PMC
Analysis of the behaviour of Dictyostelium discoideum in immobilised state by means of continuous cultivation.
BIOPROCESS AND BIOSYSTEMS ENGINEERING 26(2): 117-122. -
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2003 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1609656Voß C, Schmidt T, Schleef M, Friehs K, Flaschel E (2003)PUB | DOI | WoS | PubMed | Europe PMC
Production of supercoiled multimeric plasmid DNA for biopharmaceutical application.
JOURNAL OF BIOTECHNOLOGY 105(3): 205-213. -
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2002 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1880734Schierl F, Friehs K, Risse JM, Flaschel E (2002)PUB
Herstellung von Mediumskomponenten aus mikrobieller Biomasse.
Freiberger Forschungshefte A 866: 112-124. -
2002 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 1613125Hettwer J, Oldenburg H, Flaschel E (2002)PUB | DOI | WoS
Enzymic routes to dihydroxyacetone phosphate or immediate precursors.
In: Journal of Molecular Catalysis B: Enzymatic. JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC, 19. ELSEVIER SCIENCE BV: 215-222. -
2002 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1613472Miksch G, Kleist S, Friehs K, Flaschel E (2002)PUB | DOI | WoS | PubMed | Europe PMC
Overexpression of the phytase from Escherichia coli and its extracellular production in bioreactors.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 59(6): 685-694. -
2001 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1880242Risse JM, Friehs K, Flaschel E (2001)PUB
Recycling of Biomass Resulting from Fermentation Processes with Bacillus licheniformis.
Chem. Eng. Technol. 24(10): 141-145. -
2001 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1616886Schroter K, Flaschel E, Pühler A, Becker A (2001)PUB | DOI | WoS | PubMed | Europe PMC
Xanthomonas campestris pv. campestris secretes the endoglucanases ENGXCA and ENGXCB: construction of an endoglucanase-deficient mutant for industrial xanthan production.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 55(6): 727-733. -
2001 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 1880243Miksch G, Flaschel E (2001)PUB
Secretion of homologous and heterologous recombinant proteins in Escherichia coli and other gram-negative bacteria by using a new secretion system.
In: Recombinant protein production with prokaryotic and eukaryotic cells - A comparative view on host physiology. Selected articles from the meeting of the EFB Section on Microbial Physiology, Semmering, Austria, 5th-8th October 2000. Merten O-W, Mattanovich D, Lang C (Eds); Dordrecht: Kluwer Academic Publishers: 347-358. -
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1999 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1621141Baier R, Schiene K, Kohring B, Flaschel E, Niehaus K (1999)PUB | DOI | WoS | PubMed | Europe PMC
Alfalfa and tobacco cells react differently to chitin oligosaccharides and Sinorhizobium meliloti nodulation factors.
PLANTA 210(1): 157-164. -
1999 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1621612Schmidt T, Friehs K, Schleef M, Voß C, Flaschel E (1999)PUB | DOI | WoS | PubMed | Europe PMC
Quantitative analysis of plasmid forms by agarose and capillary gel electrophoresis.
ANALYTICAL BIOCHEMISTRY 274(2): 235-240. -
1999 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1622862Miksch G, Neitzel R, Friehs K, Flaschel E (1999)PUB | DOI | WoS | PubMed | Europe PMC
High-level expression of a recombinant protein in Klebsiella planticola owing to induced secretion into the culture medium.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 51(5): 627-632. -
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1997 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1637759Miksch G, Neitzel R, Fiedler E, Friehs K, Flaschel E (1997)PUB | DOI | WoS | PubMed | Europe PMC
Extracellular production of a hybrid beta-glucanase from Bacillus by Escherichia coli under different cultivation conditions in shaking cultures and bioreactors.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 47(2): 120-126. -
1997 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1636857Miksch G, Fiedler E, Dobrowolski P, Flaschel E (1997)PUB | DOI | WoS | PubMed | Europe PMC
Controlled secretion into the culture medium of a hybrid beta-glucanase by Acetobacter methanolicus mediated by the kil gene of Escherichia coli located on a Tn5-derived transposon.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 47(5): 530-536. -
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1997 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1626566Kohring B, Baier R, Niehaus K, Pühler A, Flaschel E (1997)PUB | DOI | WoS | PubMed | Europe PMC
Production of nodulation factors by Rhizobium meliloti: fermentation, purification and characterization of glycolipids.
GLYCOCONJUGATE JOURNAL 14(8): 963-971. -
1997 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1627108Poppenborg L, Friehs K, Flaschel E (1997)PUB | DOI | WoS | PubMed | Europe PMC
The green fluorescent protein is a versatile reporter for bioprocess monitoring.
JOURNAL OF BIOTECHNOLOGY 58(2): 79-88. -
1996 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1638581Hentsch M, Warnery P, Renken A, Flaschel E (1996)PUB | WoS
Study of the simultaneous partitioning of proteins and surfactant in reverse micellar two-phase systems - Potential impact upon purification efficiency.
BIOSEPARATION 6(2): 67-76. -
1996 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1628395Schmidt T, Friehs K, Flaschel E (1996)PUB | DOI | WoS | PubMed | Europe PMC
Rapid determination of plasmid copy number.
JOURNAL OF BIOTECHNOLOGY 49(1-3): 219-229. -
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1995 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1641313Flaschel E, Margot A, Dohmen M, Renken A (1995)PUB | DOI | WoS
Conversion-Space Time Profiles of Stirred-Tank Reactors Continuously Fed with Reactants and Catalyst under Conditions of Strong Catalyst Deactivation.
Chemical Engineering Science 50(7): 1143-1147. -
1995 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1641188HENTSCH M, Flaschel E, RENKEN A (1995)PUB | DOI | WoS
RADIOLABELED AOT FOR STUDIES OF THE PARTITIONING OF THE SURFACTANT DURING PROTEIN EXTRACTION BY MEANS OF REVERSE MICELLAR 2-PHASE SYSTEMS.
JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY-ARTICLES 191(1): 201-208. -
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