PUB - Publikationen an der Universität Bielefeld

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• [93]
  

  2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2904075

  Müller, J., Risse, J.M., Jussen, D., Flaschel, E.: Development of fed-batch strategies for the production of streptavidin by Streptomyces avidinii based on power input and oxygen supply studies (vol 163, pg 325, 2013). JOURNAL OF BIOTECHNOLOGY. 226, 76-77 (2016).

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [92]
  

  2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2906183

  Schulte, F., Flaschel, E., Niehaus, K.: Proteome-Based Analysis of Colloidal Instability Enables the Detection of Haze-Active Proteins in Beer. Journal of Agricultural and Food Chemistry. 64, 6752-6761 (2016).

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [91]
  

  2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2903023

  Wetzel, D., Müller, J., Flaschel, E., Friehs, K., Risse, J.M.: Fed-batch production and secretion of streptavidin by Hansenula polymorpha: Evaluation of genetic factors and bioprocess development. JOURNAL OF BIOTECHNOLOGY. 225, 3-9 (2016).

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [90]
  

  2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2906197

  Müller, J., Bruhn, S., Flaschel, E., Friehs, K., Risse, J.M.: GAP promoter-based fed-batch production of highly bioactive core streptavidin by Pichia pastoris. BIOTECHNOLOGY PROGRESS. 32, 855-864 (2016).

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [89]
  

  2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2900637

  Müller, J., Wetzel, D., Flaschel, E., Friehs, K., Risse, J.M.: Constitutive production and efficient secretion of soluble full-length streptavidin by an Escherichia coli 'leaky mutant'. Journal of Biotechnology. 221, 91-100 (2016).

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [88]
  

  2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2767378

  Müller, J., Risse, J.M., Friehs, K., Flaschel, E.: Model-based development of an assay for the rapid detection of biotin-blocked binding sites of streptavidin. Engineering in Life Sciences. 15, 627-639 (2015).

  PUB | DOI | WoS
   
• [87]
  

  2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2759080

  Grimm, P., Risse, J.M., Müller, J., Cholewa, D., Beshay, U., Friehs, K., Flaschel, E.: Applicability of Euglena gracilis for biorefineries demonstrated by the production of α-tocopherol and paramylon followed by anaerobic digestion. Journal of Biotechnology. 215, 72-79 (2015).

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• [86]
  

  2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2722001

  Schwarzhans, J.P., Cholewa, D., Grimm, P., Beshay, U., Risse, J.M., Friehs, K., Flaschel, E.: Dependency of the fatty acid composition of Euglena gracilis on growth phase and culture conditions. Journal of Applied Phycology. 27, 1389-1399 (2015).

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• [85]
  

  2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2679910

  Selvamani, R.S.V., Telaar, M., Friehs, K., Flaschel, E.: Antibiotic-free segregational plasmid stabilization in Escherichia coli owing to the knockout of triosephosphate isomerase (tpiA). Microbial Cell Factories. 13, : 58 (2014).

  PUB | PDF | DOI | WoS | PubMed | Europe PMC
   
• [84]
  

  2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2675672

  Selvamani, R.S.V., Friehs, K., Flaschel, E.: Extracellular recombinant protein production under continuous culture conditions with Escherichia coli using an alternative plasmid selection mechanism. Bioprocess and Biosystems Engineering. 37, 401-413 (2014).

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [83]
  

  2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2551139

  Müller, J.M., Risse, J.M., Jussen, D., Flaschel, E.: Development of fed-batch strategies for the production of streptavidin by Streptomyces avidinii based on power input and oxygen supply studies. Journal of Biotechnology. 163, 325-332 (2013).

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [82]
  

  2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1945165

  Vijayendran, C., Flaschel, E.: Impact of profiling technologies in the understanding of recombinant protein production. Adv Biochem Eng Biotechnol. 121, 45-70 (2010).

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [81]
  

  2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1929340

  Burgemeister, S., Nattkemper, T.W., Noll, T., Hoffrogge, R., Flaschel, E.: CellViCAM-Cell viability classification for animal cell cultures using dark field micrographs. JOURNAL OF BIOTECHNOLOGY. 149, 310-316 (2010).

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• [80]
  

  2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1796536

  Sommer, B., Friehs, K., Flaschel, E.: Efficient production of extracellular proteins with Escherichia coli by means of optimized coexpression of bacteriocin release proteins. JOURNAL OF BIOTECHNOLOGY. 145, 350-358 (2010).

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [79]
  

  2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1795042

  Santek, B., Felski, M., Friehs, K., Lotz, M., Flaschel, E.: Production of paramylon, a beta-1,3-glucan, by heterotrophic cultivation of Euglena gracilis on potato liquor. ENGINEERING IN LIFE SCIENCES. 10, NA (2010).

  PUB | DOI | WoS
   
• [78]
  

  2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1588919

  Spexard, M., Beshay, U., Risse, J.M., Miksch, G., Flaschel, E.: Screening for conditions of enhanced production of a recombinant beta-glucanase secreted into the medium by Escherichia coli. BIOTECHNOLOGY LETTERS. 32, 243-248 (2010).

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [77]
  

  2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1796749

  Flaschel, E.: Biocatalysis - New tasks, new approaches. CHEMIE INGENIEUR TECHNIK. 82, 3 (2010).

  PUB | DOI | WoS
   
• [76]
  

  2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1635287

  Santek, B., Felski, M., Friehs, K., Lotz, M., Flaschel, E.: Production of paramylon, a beta-1,3-glucan, by heterotrophic cultivation of Euglena gracilis on a synthetic medium. ENGINEERING IN LIFE SCIENCES. 9, 23-28 (2009).

  PUB | DOI | WoS
   
• [75]
  

  2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1591533

  Tschapalda, K., Streitner, N., Voß, C., Flaschel, E.: Generation of chromosomal DNA during alkaline lysis and removal by reverse micellar extraction. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY. 84, 199-204 (2009).

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [74]
  

  2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1636091

  Beshay, U., Miksch, G., Friehs, K., Flaschel, E.: Integrated bioprocess for the production and purification of recombinant proteins by affinity chromatography in Escherichia coli. BIOPROCESS AND BIOSYSTEMS ENGINEERING. 32, 149-158 (2009).

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [73]
  

  2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1634165

  Sommer, B., Friehs, K., Flaschel, E., Reck, M., Stahl, F., Scheper, T.: Extracellular production and affinity purification of recombinant proteins with Escherichia coli using the versatility of the maltose binding protein. JOURNAL OF BIOTECHNOLOGY. 140, 194-202 (2009).

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [72]
  

  2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1585399

  Beshay, U., Friehs, K., Flaschel, E.: Growth of myxamoebae of the cellular slime mold Dictyostelium discoideum in suspension and immobilized form on living bacteria. PROCESS BIOCHEMISTRY. 43, 1281-1287 (2008).

  PUB | DOI | WoS
   
• [71]
  

  2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1585611

  Wei, N., Flaschel, E., Friehs, K., Nattkemper, T.W.: A machine vision system for automated non-invasive assessment of cell viability via dark field microscopy, wavelet feature selection and classification. BMC Bioinformatics. 9, 449 (2008).

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• [70]
  

  2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1587590

  Vijayendran, C., Barsch, A., Friehs, K., Niehaus, K., Becker, A., Flaschel, E.: Perceiving molecular evolution processes in Escherichia coli by comprehensive metabolite and gene expression profiling. GENOME BIOLOGY. 9, R72 (2008).

  PUB | PDF | DOI | WoS | PubMed | Europe PMC
   
• [69]
  

  2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1587283

  Flaschel, E.: Can we expect a breakthrough in downstream processing of biotechnological products in the near future? Chemical Engineering & Technology. 31, 809 (2008).

  PUB | DOI | WoS
   
• [68]
  

  2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1587404

  Flaschel, E.: Renovation of biotechnological products - Faces a revolution? CHEMIE INGENIEUR TECHNIK. 80, 695 (2008).

  PUB | DOI | WoS
   
• [67]
  

  2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1587409

  Streitner, N., Voß, C., Flaschel, E.: Isolation of Plasmid-DNA by inverse micelles two phase system - Optimization of the reverse extraction. CHEMIE INGENIEUR TECHNIK. 80, 831-837 (2008).

  PUB | DOI | WoS
   
• [66]
  

  2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1585617

  Miksch, G., Ryu, S., Risse, J.M., Flaschel, E.: Factors that influence the extracellular expression of streptavidin in Escherichia coli using a bacteriocin release protein. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY. 81, 319-326 (2008).

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [65]
  

  2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1631667

  Vijayendran, C., Burgemeister, S., Friehs, K., Niehaus, K., Flaschel, E.: 2DBase: 2D-PAGE database of Escherichia coli. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 363, 822-827 (2007).

  PUB | PDF | DOI | WoS | PubMed | Europe PMC
   
• [64]
  

  2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1594835

  Vijayendran, C., Polen, T., Wendisch, V.F., Friehs, K., Niehaus, K., Flaschel, E.: The plasticity of global proteome and genome expression analyzed in closely related W3110 and MG1655 strains of a well-studied model organism, Escherichia coli-K12. Journal of Biotechnology. 128, 747-761 (2007).

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [63]
  

  2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1595739

  Wei, N., You, J., Friehs, K., Flaschel, E., Nattkemper, T.W.: In situ dark field microscopy for on-line monitoring of yeast cultures. BIOTECHNOLOGY LETTERS. 29, 373-378 (2007).

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [62]
  

  2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1593120

  Wei, N., You, J., Friehs, K., Flaschel, E., Nattkemper, T.W.: An in situ probe for on-line monitoring of cell density and viability on the basis of dark field microscopy in conjunction with image processing and supervised machine learning. Biotechnology and Bioengineering. 97, 1489-1500 (2007).

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [61]
  

  2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1632656

  Streitner, N., Voß, C., Flaschel, E.: Reverse micellar extraction systems for the purification of pharmaceutical grade plasmid DNA. JOURNAL OF BIOTECHNOLOGY. 131, 188-196 (2007).

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [60]
  

  2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1593482

  Beshay, U., Miksch, G., Friehs, K., Flaschel, E.: Improved beta-glucanase production by a recombinant Escherichia coli strain using a zinc-ion supplemented medium. ENGINEERING IN LIFE SCIENCES. 7, 253-258 (2007).

  PUB | DOI | WoS
   
• [59]
  

  2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1593326

  Beshay, U., Miksch, G., Flaschel, E.: Improvement of a beta-glucanase activity test by taking into account the batch reactor balance of the test system. BIOPROCESS AND BIOSYSTEMS ENGINEERING. 30, 251-259 (2007).

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [58]
  

  2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1631107

  Blaesen, M., Friehs, K., Flaschel, E.: Recycling of bacterial biomass in a process of L-threonine production by means of a recombinant strain of Escherichia coli. JOURNAL OF BIOTECHNOLOGY. 132, 431-437 (2007).

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [57]
  

  2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1631661

  Beshay, U., Miksch, G., Friehs, K., Flaschel, E.: Increasing the secretion ability of the kil gene for recombinant proteins in Escherichia coli by using a strong stationary-phase promoter. BIOTECHNOLOGY LETTERS. 29, 1893-1901 (2007).

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [56]
  

  2006 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1599823

  Flaschel, E., Hempel, D.: White biotechnology. CHEMIE INGENIEUR TECHNIK. 78, 153 (2006).

  PUB | DOI | WoS
   
• [55]
  

  2006 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 1599661

  Flaschel, E.: Reactor performance in the presence of catalyst deactivation. Engineering in Life Sciences. ENGINEERING IN LIFE SCIENCES. 6, p. 131-138. Wiley-VCH (2006).

  PUB | DOI | WoS
   
• [54]
  

  2006 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1600329

  Miksch, G., Bettenworth, F., Friehs, K., Flaschel, E., Saalbach, A., Nattkemper, T.W.: A rapid reporter system using GFP as a reporter protein for identification and screening of synthetic stationary-phase promoters in Escherichia coli. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY. 70, 229-236 (2006).

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [53]
  

  2006 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1597472

  Blaesen, M., Flaschel, E., Friehs, K.: Sustainable production: Recycling of bacterial biomass resulting from a fermentation process with Klebsiella planticola. CHEMICAL AND BIOCHEMICAL ENGINEERING QUARTERLY. 20, 263-268 (2006).

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• [52]
  

  2006 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1599112

  Voß, C., Lindau, D., Flaschel, E.: Production of recombinant RNase Ba and its application in downstream processing of plasmid DNA for pharmaceutical use. BIOTECHNOLOGY PROGRESS. 22, 737-744 (2006).

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [51]
  

  2005 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2906664

  Polen, T., Wendisch, V.F., Friehs, K., Niehaus, K., Flaschel, E., Vijayendran, C.: The plasticity of global proteome and genome expression analysis in a well studied closely related model organism, Escherichia coli. MOLECULAR & CELLULAR PROTEOMICS. 4, S248-S248 (2005).

  PUB | WoS
   
• [50]
  

  2005 | Monographie | PUB-ID: 2714309

  Bettenworth, F., Miksch, G., Fries, K., Flaschel, E., Saalbach, A., Eickmeyer, J., Nattkemper, T.W.: An Online Monitoring System for the Screening of Stationary-Phase Promoters in E. Coli using GFP as a Reporter Protein. (2005).

  PUB
   
• [49]
  

  2005 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1604386

  Arndt, M., Kleist, S., Miksch, G., Friehs, K., Flaschel, E., Trierweiler, J., Hitzmann, B.: A feedforward-feedback substrate controller based on a Kalman filter for a fed-batch cultivation of Escherichia coli producing phytase. COMPUTERS & CHEMICAL ENGINEERING. 29, 1113-1120 (2005).

  PUB | DOI | WoS
   
• [48]
  

  2005 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1946602

  Wei, N., Flaschel, E., Saalbach, A., Twellmann, T., Nattkemper, T.W.: Reagent-free automatic cell viability determination using neural networks based machine vision and dark-field microscopy in Saccharomyces cerevisiae. Conf Proc IEEE Eng Med Biol Soc. 6, 6305-6308 (2005).

  PUB | DOI | PubMed | Europe PMC
   
• [47]
  

  2005 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1601074

  Miksch, G., Bettenworth, F., Friehs, K., Flaschel, E.: The sequence upstream of the -10 consensus sequence modulates the strength and induction time of stationary-phase promoters in Escherichia coli. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY. 69, 312-320 (2005).

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [46]
  

  2005 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 1601848

  Miksch, G., Bettenworth, F., Friehs, K., Flaschel, E., Saalbach, A., Twellmann, T., Nattkemper, T.W.: Libraries of synthetic stationary-phase and stress promoters as a tool for fine-tuning of expression of recombinant proteins in Escherichia coli. Journal of Biotechnology. JOURNAL OF BIOTECHNOLOGY. 120, p. 25-37. ELSEVIER SCIENCE BV (2005).

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• [45]
  

  2005 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1604877

  Risse, J.M., Pühler, A., Flaschel, E.: Production of N-acetyl-phosphinothricin: A substance used for inducing male sterility in transgenic plants. ENGINEERING IN LIFE SCIENCES. 5, 38-45 (2005).

  PUB | DOI | WoS
   
• [44]
  

  2005 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 1601124

  Vijayendran, C., Polen, T., Wendisch, V., Friehs, K., Niehaus, K., Flaschel, E.: The plasticity of global proteome and genome expression analysis in a well studied closely related model organism, Escherichia coli. Molecular & Cellular Proteomics. 4, S248 (2005).

  PUB | WoS
   
• [43]
  

  2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1608845

  Han, S.I., Friehs, K., Flaschel, E.: Cultivation of Dictyostelium discoideum on an improved synthetic medium in a conventional bioreactor. PROCESS BIOCHEMISTRY. 39, 585-589 (2004).

  PUB | DOI | WoS
   
• [42]
  

  2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1607969

  Han, S.I., Friehs, K., Flaschel, E.: Improvement of a synthetic medium for Dictyostelium discoideum. PROCESS BIOCHEMISTRY. 39, 925-930 (2004).

  PUB | DOI | WoS
   
• [41]
  

  2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1609051

  Voß, C., Schmidt, T., Schleef, M., Friehs, K., Flaschel, E.: Effect of ammonium chloride on plasmid DNA production in high cell density batch culture for biopharmaceutical use. JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY. 79, 57-62 (2004).

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• [40]
  

  2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1608382

  Lu, Y.H., Knol, J.C., Linskens, M.H.K., Friehs, K., van Haastert, P.J.M., Flaschel, E.: Production of the soluble human Fas ligand by Dictyostelium discoideum cultivated on a synthetic medium. JOURNAL OF BIOTECHNOLOGY. 108, 243-251 (2004).

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• [39]
  

  2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1606278

  Lu, Y.H., Knol, J.C., Linskens, M.H.K., Friehs, K., van Haastert, P.J.M., Flaschel, E.: Cultivation of immobilized Dictyostelium discoideum for the production of soluble human Fas ligand. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY. 65, 547-552 (2004).

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• [38]
  

  2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1606443

  Lu, Y.H., Beshay, U., Friehs, K., Flaschel, E.: Mass production of Dictyostelium discoideum in homogenous and hetergeneous cultivation systems. PROCESS BIOCHEMISTRY. 39, 1859-1870 (2004).

  PUB | DOI | WoS
   
• [37]
  

  2003 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1609437

  Beshay, U., Friehs, K., Azzam, A.E.M., Flaschel, E.: Analysis of the behaviour of Dictyostelium discoideum in immobilised state by means of continuous cultivation. BIOPROCESS AND BIOSYSTEMS ENGINEERING. 26, 117-122 (2003).

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [36]
  

  2003 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 1610736

  Schleef, M., Voß, C., Schmidt, T., Flaschel, E.: Plasmid topology - An important factor influencing the performance of DNA drug delivery. JOURNAL OF LIPOSOME RESEARCH. 13, 82-83 (2003).

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• [35]
  

  2003 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1610824

  Beshay, U., Friehs, K., Azzam, A.E.M., Flaschel, E.: Cultivation of Dictyostelium discoideum in immobilized form by colonization of porous supports. PROCESS BIOCHEMISTRY. 38, 1521-1529 (2003).

  PUB | DOI | WoS
   
• [34]
  

  2003 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 1610932

  Schleef, M., Voß, C., Schmidt, T., Flaschel, E.: Plasmid vector stability in production, application and storage. JOURNAL OF GENE MEDICINE. 5, S26-S26 (2003).

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• [33]
  

  2003 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1609656

  Voß, C., Schmidt, T., Schleef, M., Friehs, K., Flaschel, E.: Production of supercoiled multimeric plasmid DNA for biopharmaceutical application. JOURNAL OF BIOTECHNOLOGY. 105, 205-213 (2003).

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• [32]
  

  2003 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1609485

  Stephan, M., Beshay, U., Friehs, K., Flaschel, E.: Influence of medium composition on growth behaviour of Dictyostelium discoideum for cultivation on axenic media. PROCESS BIOCHEMISTRY. 39, 333-343 (2003).

  PUB | DOI | WoS
   
• [31]
  

  2002 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1880734

  Schierl, F., Friehs, K., Risse, J.M., Flaschel, E.: Herstellung von Mediumskomponenten aus mikrobieller Biomasse. Freiberger Forschungshefte. A 866, 112-124 (2002).

  PUB
   
• [30]
  

  2002 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 1613125

  Hettwer, J., Oldenburg, H., Flaschel, E.: Enzymic routes to dihydroxyacetone phosphate or immediate precursors. Journal of Molecular Catalysis B: Enzymatic. JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC. 19, p. 215-222. ELSEVIER SCIENCE BV (2002).

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• [29]
  

  2002 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1613472

  Miksch, G., Kleist, S., Friehs, K., Flaschel, E.: Overexpression of the phytase from Escherichia coli and its extracellular production in bioreactors. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY. 59, 685-694 (2002).

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [28]
  

  2001 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1880242

  Risse, J.M., Friehs, K., Flaschel, E.: Recycling of Biomass Resulting from Fermentation Processes with Bacillus licheniformis. Chem. Eng. Technol. 24, 141-145 (2001).

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• [27]
  

  2001 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1616886

  Schroter, K., Flaschel, E., Pühler, A., Becker, A.: Xanthomonas campestris pv. campestris secretes the endoglucanases ENGXCA and ENGXCB: construction of an endoglucanase-deficient mutant for industrial xanthan production. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY. 55, 727-733 (2001).

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [26]
  

  2001 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 1880243

  Miksch, G., Flaschel, E.: Secretion of homologous and heterologous recombinant proteins in Escherichia coli and other gram-negative bacteria by using a new secretion system. In: Merten, O.-W., Mattanovich, D., and Lang, C. (eds.) Recombinant protein production with prokaryotic and eukaryotic cells - A comparative view on host physiology. Selected articles from the meeting of the EFB Section on Microbial Physiology, Semmering, Austria, 5th-8th October 2000. p. 347-358. Kluwer Academic Publishers, Dordrecht (2001).

  PUB
   
• [25]
  

  2000 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1619389

  Risse, J.M., Friehs, K., Flaschel, E.: Biomasserückführung am Beispiel Bacillus licheniformis. CHEMIE INGENIEUR TECHNIK. 72, 750-754 (2000).

  PUB | DOI | WoS
   
• [24]
  

  1999 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1621141

  Baier, R., Schiene, K., Kohring, B., Flaschel, E., Niehaus, K.: Alfalfa and tobacco cells react differently to chitin oligosaccharides and Sinorhizobium meliloti nodulation factors. PLANTA. 210, 157-164 (1999).

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [23]
  

  1999 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1621612

  Schmidt, T., Friehs, K., Schleef, M., Voß, C., Flaschel, E.: Quantitative analysis of plasmid forms by agarose and capillary gel electrophoresis. ANALYTICAL BIOCHEMISTRY. 274, 235-240 (1999).

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [22]
  

  1999 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1622862

  Miksch, G., Neitzel, R., Friehs, K., Flaschel, E.: High-level expression of a recombinant protein in Klebsiella planticola owing to induced secretion into the culture medium. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY. 51, 627-632 (1999).

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [21]
  

  1998 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1625697

  Friehs, K., Schierl, F., Flaschel, E.: Reprocessing of bacterial biomass for recycling as a medium component in fermentation processes. CHEMIE INGENIEUR TECHNIK. 70, 435-437 (1998).

  PUB | DOI | WoS
   
• [20]
  

  1998 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1626311

  Margot, A., Flaschel, E., Renken, A.: Development of a continuously operated reactor for the limited hydrolysis of whey protein by trypsin. PROCESS BIOCHEMISTRY. 33, 125-131 (1998).

  PUB | DOI | WoS
   
• [19]
  

  1998 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1626283

  Huneke, F.U., Flaschel, E.: Behaviour of liquid/liquid/solid three-phase fixed bed reactors with application in biocatalysis. JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY. 71, 213-222 (1998).

  PUB | DOI | WoS
   
• [18]
  

  1997 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1637759

  Miksch, G., Neitzel, R., Fiedler, E., Friehs, K., Flaschel, E.: Extracellular production of a hybrid beta-glucanase from Bacillus by Escherichia coli under different cultivation conditions in shaking cultures and bioreactors. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY. 47, 120-126 (1997).

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [17]
  

  1997 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1636857

  Miksch, G., Fiedler, E., Dobrowolski, P., Flaschel, E.: Controlled secretion into the culture medium of a hybrid beta-glucanase by Acetobacter methanolicus mediated by the kil gene of Escherichia coli located on a Tn5-derived transposon. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY. 47, 530-536 (1997).

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [16]
  

  1997 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1628040

  Margot, A., Flaschel, E., Renken, A.: Empirical kinetic models for tryptic whey-protein hydrolysis. PROCESS BIOCHEMISTRY. 32, 217-223 (1997).

  PUB | DOI | WoS
   
• [15]
  

  1997 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1626566

  Kohring, B., Baier, R., Niehaus, K., Pühler, A., Flaschel, E.: Production of nodulation factors by Rhizobium meliloti: fermentation, purification and characterization of glycolipids. GLYCOCONJUGATE JOURNAL. 14, 963-971 (1997).

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [14]
  

  1997 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1627108

  Poppenborg, L., Friehs, K., Flaschel, E.: The green fluorescent protein is a versatile reporter for bioprocess monitoring. JOURNAL OF BIOTECHNOLOGY. 58, 79-88 (1997).

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [13]
  

  1996 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1638581

  Hentsch, M., Warnery, P., Renken, A., Flaschel, E.: Study of the simultaneous partitioning of proteins and surfactant in reverse micellar two-phase systems - Potential impact upon purification efficiency. BIOSEPARATION. 6, 67-76 (1996).

  PUB | WoS
   
• [12]
  

  1996 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1628395

  Schmidt, T., Friehs, K., Flaschel, E.: Rapid determination of plasmid copy number. JOURNAL OF BIOTECHNOLOGY. 49, 219-229 (1996).

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [11]
  

  1996 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 1639656

  Schmidt, T., Friehs, K., Flaschel, E.: Plasmid copy number as a process variable for fermentation control. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. 211, 191-BIOT (1996).

  PUB | WoS
   
• [10]
  

  1995 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1641313

  Flaschel, E., Margot, A., Dohmen, M., Renken, A.: Conversion-Space Time Profiles of Stirred-Tank Reactors Continuously Fed with Reactants and Catalyst under Conditions of Strong Catalyst Deactivation. Chemical Engineering Science. 50, 1143-1147 (1995).

  PUB | DOI | WoS
   
• [9]
  

  1995 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1641188

  HENTSCH, M., Flaschel, E., RENKEN, A.: RADIOLABELED AOT FOR STUDIES OF THE PARTITIONING OF THE SURFACTANT DURING PROTEIN EXTRACTION BY MEANS OF REVERSE MICELLAR 2-PHASE SYSTEMS. JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY-ARTICLES. 191, 201-208 (1995).

  PUB | DOI | WoS
   
• [8]
  

  1994 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1644182

  MARGOT, A., Flaschel, E., RENKEN, A.: CONTINUOUS MONITORING OF ENZYMATIC WHEY-PROTEIN HYDROLYSIS - CORRELATION OF BASE CONSUMPTION WITH SOLUBLE NITROGEN-CONTENT. PROCESS BIOCHEMISTRY. 29, 257-262 (1994).

  PUB | DOI | WoS
   
• [7]
  

  1994 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1641804

  HUNEKE, F.U., Flaschel, E.: PHASE DISTRIBUTION IN LIQUID-LIQUID 3-PHASE FIXED-BED REACTORS. CHEMIE INGENIEUR TECHNIK. 66, 1649-1651 (1994).

  PUB | DOI | WoS
   
• [6]
  

  1994 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 1643205

  Flaschel, E., SCHAFFER, T.: NEW EVIDENCE FOR DIMERIZATION-DEPENDENCE OF THE ACTIVITY OF CANDIDA-RUGOSA LIPASE. Biocatalysis. BIOCATALYSIS. 9, p. 241-248. HARWOOD ACAD PUBL GMBH (1994).

  PUB | DOI | WoS
   
• [5]
  

  1994 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1643820

  POPPENBORG, L., Flaschel, E.: AFFINITY EXTRACTION OF PROTEINS BY MEANS OF REVERSE MICELLAR PHASES CONTAINING A METAL-CHELATING SURFACTANT. BIOTECHNOLOGY TECHNIQUES. 8, 307-312 (1994).

  PUB | DOI | WoS
   
• [4]
  

  1993 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1646173

  Flaschel, E., Friehs, K.: Improvement of downstream processing of recombinant proteins by means of genetic engineering. Biotechnology Advances. 11, 31-77 (1993).

  PUB | PDF | DOI | WoS | PubMed | Europe PMC
   
• [3]
  

  1992 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1629782

  Hentsch, M., Menoud, P., Flaschel, E., Renken, A.: The effect of temperature on the kinetics of a reverse micellar protein extraction process. BIOTECHNOLOGY TECHNIQUES. 6, 423-428 (1992).

  PUB | WoS
   
• [2]
  

  1992 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1629787

  Hentsch, M., Menoud, P., Steiner, L., Flaschel, E., Renken, A.: Optimization of the surfactant (AOT) concentration in a reverse micellar extraction process. BIOTECHNOLOGY TECHNIQUES. 6, 359-364 (1992).

  PUB | DOI | WoS
   
• [1]
  

  1992 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1647759

  MARGOT, A., RICHOZ, C., Flaschel, E., RENKEN, A.: INFLUENCE OF TRYPSIN DEACTIVATION ON THE HYDROLYSIS OF WHEY PROTEINS. CHEMIE INGENIEUR TECHNIK. 64, 551-553 (1992).

  PUB | DOI | WoS