PUB - Publikationen an der Universität Bielefeld

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• [93]
  

  2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2904075

  Müller, J.; Risse, J. M.; Jussen, D.; Flaschel, E. (2016): Development of fed-batch strategies for the production of streptavidin by Streptomyces avidinii based on power input and oxygen supply studies (vol 163, pg 325, 2013) JOURNAL OF BIOTECHNOLOGY,226: 76-77.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [92]
  

  2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2906183

  Schulte, F.; Flaschel, E.; Niehaus, K. (2016): Proteome-Based Analysis of Colloidal Instability Enables the Detection of Haze-Active Proteins in Beer Journal of Agricultural and Food Chemistry,64:(35): 6752-6761.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [91]
  

  2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2903023

  Wetzel, D.; Müller, J.; Flaschel, E.; Friehs, K.; Risse, J. M. (2016): Fed-batch production and secretion of streptavidin by Hansenula polymorpha: Evaluation of genetic factors and bioprocess development JOURNAL OF BIOTECHNOLOGY,225: 3-9.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [90]
  

  2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2906197

  Müller, J.; Bruhn, S.; Flaschel, E.; Friehs, K.; Risse, J. M. (2016): GAP promoter-based fed-batch production of highly bioactive core streptavidin by Pichia pastoris BIOTECHNOLOGY PROGRESS,32:(4): 855-864.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [89]
  

  2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2900637

  Müller, J.; Wetzel, D.; Flaschel, E.; Friehs, K.; Risse, J. M. (2016): Constitutive production and efficient secretion of soluble full-length streptavidin by an Escherichia coli 'leaky mutant' Journal of Biotechnology,221: 91-100.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [88]
  

  2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2767378

  Müller, J.; Risse, J. M.; Friehs, K.; Flaschel, E. (2015): Model-based development of an assay for the rapid detection of biotin-blocked binding sites of streptavidin Engineering in Life Sciences,15:(6): 627-639.

  PUB | DOI | WoS
   
• [87]
  

  2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2759080

  Grimm, P.; Risse, J. M.; Müller, J.; Cholewa, D.; Beshay, U.; Friehs, K.; Flaschel, E. (2015): Applicability of Euglena gracilis for biorefineries demonstrated by the production of α-tocopherol and paramylon followed by anaerobic digestion Journal of Biotechnology,215: 72-79.

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• [86]
  

  2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2722001

  Schwarzhans, J. P.; Cholewa, D.; Grimm, P.; Beshay, U.; Risse, J. M.; Friehs, K.; Flaschel, E. (2015): Dependency of the fatty acid composition of Euglena gracilis on growth phase and culture conditions Journal of Applied Phycology,27:(4): 1389-1399.

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• [85]
  

  2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2679910

  Selvamani, R. S. V.; Telaar, M.; Friehs, K.; Flaschel, E. (2014): Antibiotic-free segregational plasmid stabilization in Escherichia coli owing to the knockout of triosephosphate isomerase (tpiA) Microbial Cell Factories,13:(1):58

  PUB | PDF | DOI | WoS | PubMed | Europe PMC
   
• [84]
  

  2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2675672

  Selvamani, R. S. V.; Friehs, K.; Flaschel, E. (2014): Extracellular recombinant protein production under continuous culture conditions with Escherichia coli using an alternative plasmid selection mechanism Bioprocess and Biosystems Engineering,37:(3): 401-413.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [83]
  

  2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2551139

  Müller, J. M.; Risse, J. M.; Jussen, D.; Flaschel, E. (2013): Development of fed-batch strategies for the production of streptavidin by Streptomyces avidinii based on power input and oxygen supply studies Journal of Biotechnology,163:(3): 325-332.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [82]
  

  2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1945165

  Vijayendran, C.; Flaschel, E. (2010): Impact of profiling technologies in the understanding of recombinant protein production Adv Biochem Eng Biotechnol,121: 45-70.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [81]
  

  2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1929340

  Burgemeister, S.; Nattkemper, T. W.; Noll, T.; Hoffrogge, R.; Flaschel, E. (2010): CellViCAM-Cell viability classification for animal cell cultures using dark field micrographs JOURNAL OF BIOTECHNOLOGY,149:(4): 310-316.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [80]
  

  2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1796536

  Sommer, B.; Friehs, K.; Flaschel, E. (2010): Efficient production of extracellular proteins with Escherichia coli by means of optimized coexpression of bacteriocin release proteins JOURNAL OF BIOTECHNOLOGY,145:(4): 350-358.

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• [79]
  

  2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1795042

  Santek, B.; Felski, M.; Friehs, K.; Lotz, M.; Flaschel, E. (2010): Production of paramylon, a beta-1,3-glucan, by heterotrophic cultivation of Euglena gracilis on potato liquor ENGINEERING IN LIFE SCIENCES,10:(2): NA.

  PUB | DOI | WoS
   
• [78]
  

  2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1588919

  Spexard, M.; Beshay, U.; Risse, J. M.; Miksch, G.; Flaschel, E. (2010): Screening for conditions of enhanced production of a recombinant beta-glucanase secreted into the medium by Escherichia coli BIOTECHNOLOGY LETTERS,32:(2): 243-248.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [77]
  

  2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1796749

  Flaschel, E. (2010): Biocatalysis - New tasks, new approaches CHEMIE INGENIEUR TECHNIK,82:(1-2): 3.

  PUB | DOI | WoS
   
• [76]
  

  2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1635287

  Santek, B.; Felski, M.; Friehs, K.; Lotz, M.; Flaschel, E. (2009): Production of paramylon, a beta-1,3-glucan, by heterotrophic cultivation of Euglena gracilis on a synthetic medium ENGINEERING IN LIFE SCIENCES,9:(1): 23-28.

  PUB | DOI | WoS
   
• [75]
  

  2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1591533

  Tschapalda, K.; Streitner, N.; Voß, C.; Flaschel, E. (2009): Generation of chromosomal DNA during alkaline lysis and removal by reverse micellar extraction APPLIED MICROBIOLOGY AND BIOTECHNOLOGY,84:(1): 199-204.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [74]
  

  2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1636091

  Beshay, U.; Miksch, G.; Friehs, K.; Flaschel, E. (2009): Integrated bioprocess for the production and purification of recombinant proteins by affinity chromatography in Escherichia coli BIOPROCESS AND BIOSYSTEMS ENGINEERING,32:(2): 149-158.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [73]
  

  2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1634165

  Sommer, B.; Friehs, K.; Flaschel, E.; Reck, M.; Stahl, F.; Scheper, T. (2009): Extracellular production and affinity purification of recombinant proteins with Escherichia coli using the versatility of the maltose binding protein JOURNAL OF BIOTECHNOLOGY,140:(3-4): 194-202.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [72]
  

  2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1585399

  Beshay, U.; Friehs, K.; Flaschel, E. (2008): Growth of myxamoebae of the cellular slime mold Dictyostelium discoideum in suspension and immobilized form on living bacteria PROCESS BIOCHEMISTRY,43:(11): 1281-1287.

  PUB | DOI | WoS
   
• [71]
  

  2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1585611

  Wei, N.; Flaschel, E.; Friehs, K.; Nattkemper, T. W. (2008): A machine vision system for automated non-invasive assessment of cell viability via dark field microscopy, wavelet feature selection and classification BMC Bioinformatics,9:(1): 449.

  PUB | PDF | DOI | WoS | PubMed | Europe PMC
   
• [70]
  

  2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1587590

  Vijayendran, C.; Barsch, A.; Friehs, K.; Niehaus, K.; Becker, A.; Flaschel, E. (2008): Perceiving molecular evolution processes in Escherichia coli by comprehensive metabolite and gene expression profiling GENOME BIOLOGY,9:(4): R72.

  PUB | PDF | DOI | WoS | PubMed | Europe PMC
   
• [69]
  

  2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1587283

  Flaschel, E. (2008): Can we expect a breakthrough in downstream processing of biotechnological products in the near future? Chemical Engineering & Technology,31:(6): 809.

  PUB | DOI | WoS
   
• [68]
  

  2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1587404

  Flaschel, E. (2008): Renovation of biotechnological products - Faces a revolution? CHEMIE INGENIEUR TECHNIK,80:(6): 695.

  PUB | DOI | WoS
   
• [67]
  

  2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1587409

  Streitner, N.; Voß, C.; Flaschel, E. (2008): Isolation of Plasmid-DNA by inverse micelles two phase system - Optimization of the reverse extraction CHEMIE INGENIEUR TECHNIK,80:(6): 831-837.

  PUB | DOI | WoS
   
• [66]
  

  2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1585617

  Miksch, G.; Ryu, S.; Risse, J. M.; Flaschel, E. (2008): Factors that influence the extracellular expression of streptavidin in Escherichia coli using a bacteriocin release protein APPLIED MICROBIOLOGY AND BIOTECHNOLOGY,81:(2): 319-326.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [65]
  

  2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1631667

  Vijayendran, C.; Burgemeister, S.; Friehs, K.; Niehaus, K.; Flaschel, E. (2007): 2DBase: 2D-PAGE database of Escherichia coli BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,363:(3): 822-827.

  PUB | PDF | DOI | WoS | PubMed | Europe PMC
   
• [64]
  

  2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1594835

  Vijayendran, C.; Polen, T.; Wendisch, V. F.; Friehs, K.; Niehaus, K.; Flaschel, E. (2007): The plasticity of global proteome and genome expression analyzed in closely related W3110 and MG1655 strains of a well-studied model organism, Escherichia coli-K12 Journal of Biotechnology,128:(4): 747-761.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [63]
  

  2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1595739

  Wei, N.; You, J.; Friehs, K.; Flaschel, E.; Nattkemper, T. W. (2007): In situ dark field microscopy for on-line monitoring of yeast cultures BIOTECHNOLOGY LETTERS,29:(3): 373-378.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [62]
  

  2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1593120

  Wei, N.; You, J.; Friehs, K.; Flaschel, E.; Nattkemper, T. W. (2007): An in situ probe for on-line monitoring of cell density and viability on the basis of dark field microscopy in conjunction with image processing and supervised machine learning Biotechnology and Bioengineering,97:(6): 1489-1500.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [61]
  

  2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1632656

  Streitner, N.; Voß, C.; Flaschel, E. (2007): Reverse micellar extraction systems for the purification of pharmaceutical grade plasmid DNA JOURNAL OF BIOTECHNOLOGY,131:(2): 188-196.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [60]
  

  2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1593482

  Beshay, U.; Miksch, G.; Friehs, K.; Flaschel, E. (2007): Improved beta-glucanase production by a recombinant Escherichia coli strain using a zinc-ion supplemented medium ENGINEERING IN LIFE SCIENCES,7:(3): 253-258.

  PUB | DOI | WoS
   
• [59]
  

  2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1593326

  Beshay, U.; Miksch, G.; Flaschel, E. (2007): Improvement of a beta-glucanase activity test by taking into account the batch reactor balance of the test system BIOPROCESS AND BIOSYSTEMS ENGINEERING,30:(4): 251-259.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [58]
  

  2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1631107

  Blaesen, M.; Friehs, K.; Flaschel, E. (2007): Recycling of bacterial biomass in a process of L-threonine production by means of a recombinant strain of Escherichia coli JOURNAL OF BIOTECHNOLOGY,132:(4): 431-437.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [57]
  

  2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1631661

  Beshay, U.; Miksch, G.; Friehs, K.; Flaschel, E. (2007): Increasing the secretion ability of the kil gene for recombinant proteins in Escherichia coli by using a strong stationary-phase promoter BIOTECHNOLOGY LETTERS,29:(12): 1893-1901.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [56]
  

  2006 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1599823

  Flaschel, E.; Hempel, D. (2006): White biotechnology CHEMIE INGENIEUR TECHNIK,78:(3): 153.

  PUB | DOI | WoS
   
• [55]
  

  2006 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 1599661

  Flaschel, E. (2006): Reactor performance in the presence of catalyst deactivation. In: Engineering in Life Sciences. Wiley-VCH. (ENGINEERING IN LIFE SCIENCES, 6). S. 131-138.

  PUB | DOI | WoS
   
• [54]
  

  2006 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1600329

  Miksch, G.; Bettenworth, F.; Friehs, K.; Flaschel, E.; Saalbach, A.; Nattkemper, T. W. (2006): A rapid reporter system using GFP as a reporter protein for identification and screening of synthetic stationary-phase promoters in Escherichia coli APPLIED MICROBIOLOGY AND BIOTECHNOLOGY,70:(2): 229-236.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [53]
  

  2006 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1597472

  Blaesen, M.; Flaschel, E.; Friehs, K. (2006): Sustainable production: Recycling of bacterial biomass resulting from a fermentation process with Klebsiella planticola CHEMICAL AND BIOCHEMICAL ENGINEERING QUARTERLY,20:(3): 263-268.

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• [52]
  

  2006 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1599112

  Voß, C.; Lindau, D.; Flaschel, E. (2006): Production of recombinant RNase Ba and its application in downstream processing of plasmid DNA for pharmaceutical use BIOTECHNOLOGY PROGRESS,22:(3): 737-744.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [51]
  

  2005 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2906664

  Polen, T.; Wendisch, V. F.; Friehs, K.; Niehaus, K.; Flaschel, E.; Vijayendran, C. (2005): The plasticity of global proteome and genome expression analysis in a well studied closely related model organism, Escherichia coli MOLECULAR & CELLULAR PROTEOMICS,4:(8): S248-S248.

  PUB | WoS
   
• [50]
  

  2005 | Monographie | PUB-ID: 2714309

  Bettenworth, F.; Miksch, G.; Fries, K.; Flaschel, E.; Saalbach, A.; Eickmeyer, J.; Nattkemper, T. W. (2005): An Online Monitoring System for the Screening of Stationary-Phase Promoters in E. Coli using GFP as a Reporter Protein.

  PUB
   
• [49]
  

  2005 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1604386

  Arndt, M.; Kleist, S.; Miksch, G.; Friehs, K.; Flaschel, E.; Trierweiler, J.; Hitzmann, B. (2005): A feedforward-feedback substrate controller based on a Kalman filter for a fed-batch cultivation of Escherichia coli producing phytase COMPUTERS & CHEMICAL ENGINEERING,29:(5): 1113-1120.

  PUB | DOI | WoS
   
• [48]
  

  2005 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1946602

  Wei, N.; Flaschel, E.; Saalbach, A.; Twellmann, T.; Nattkemper, T. W. (2005): Reagent-free automatic cell viability determination using neural networks based machine vision and dark-field microscopy in Saccharomyces cerevisiae Conf Proc IEEE Eng Med Biol Soc,6: 6305-6308.

  PUB | DOI | PubMed | Europe PMC
   
• [47]
  

  2005 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1601074

  Miksch, G.; Bettenworth, F.; Friehs, K.; Flaschel, E. (2005): The sequence upstream of the -10 consensus sequence modulates the strength and induction time of stationary-phase promoters in Escherichia coli APPLIED MICROBIOLOGY AND BIOTECHNOLOGY,69:(3): 312-320.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [46]
  

  2005 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 1601848

  Miksch, G.; Bettenworth, F.; Friehs, K.; Flaschel, E.; Saalbach, A.; Twellmann, T.; Nattkemper, T. W. (2005): Libraries of synthetic stationary-phase and stress promoters as a tool for fine-tuning of expression of recombinant proteins in Escherichia coli. In: Journal of Biotechnology. ELSEVIER SCIENCE BV. (JOURNAL OF BIOTECHNOLOGY, 120). S. 25-37.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [45]
  

  2005 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1604877

  Risse, J. M.; Pühler, A.; Flaschel, E. (2005): Production of N-acetyl-phosphinothricin: A substance used for inducing male sterility in transgenic plants ENGINEERING IN LIFE SCIENCES,5:(1): 38-45.

  PUB | DOI | WoS
   
• [44]
  

  2005 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 1601124

  Vijayendran, C.; Polen, T.; Wendisch, V.; Friehs, K.; Niehaus, K.; Flaschel, E. (2005): The plasticity of global proteome and genome expression analysis in a well studied closely related model organism, Escherichia coli Molecular & Cellular Proteomics,4:(8: Suppl. 1): S248.

  PUB | WoS
   
• [43]
  

  2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1608845

  Han, S. I.; Friehs, K.; Flaschel, E. (2004): Cultivation of Dictyostelium discoideum on an improved synthetic medium in a conventional bioreactor PROCESS BIOCHEMISTRY,39:(5): 585-589.

  PUB | DOI | WoS
   
• [42]
  

  2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1607969

  Han, S. I.; Friehs, K.; Flaschel, E. (2004): Improvement of a synthetic medium for Dictyostelium discoideum PROCESS BIOCHEMISTRY,39:(8): 925-930.

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• [41]
  

  2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1609051

  Voß, C.; Schmidt, T.; Schleef, M.; Friehs, K.; Flaschel, E. (2004): Effect of ammonium chloride on plasmid DNA production in high cell density batch culture for biopharmaceutical use JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY,79:(1): 57-62.

  PUB | DOI | WoS
   
• [40]
  

  2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1608382

  Lu, Y. H.; Knol, J. C.; Linskens, M. H. K.; Friehs, K.; van Haastert, P. J. M.; Flaschel, E. (2004): Production of the soluble human Fas ligand by Dictyostelium discoideum cultivated on a synthetic medium JOURNAL OF BIOTECHNOLOGY,108:(3): 243-251.

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• [39]
  

  2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1606278

  Lu, Y. H.; Knol, J. C.; Linskens, M. H. K.; Friehs, K.; van Haastert, P. J. M.; Flaschel, E. (2004): Cultivation of immobilized Dictyostelium discoideum for the production of soluble human Fas ligand APPLIED MICROBIOLOGY AND BIOTECHNOLOGY,65:(5): 547-552.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [38]
  

  2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1606443

  Lu, Y. H.; Beshay, U.; Friehs, K.; Flaschel, E. (2004): Mass production of Dictyostelium discoideum in homogenous and hetergeneous cultivation systems PROCESS BIOCHEMISTRY,39:(12): 1859-1870.

  PUB | DOI | WoS
   
• [37]
  

  2003 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1609437

  Beshay, U.; Friehs, K.; Azzam, A. E. M.; Flaschel, E. (2003): Analysis of the behaviour of Dictyostelium discoideum in immobilised state by means of continuous cultivation BIOPROCESS AND BIOSYSTEMS ENGINEERING,26:(2): 117-122.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [36]
  

  2003 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 1610736

  Schleef, M.; Voß, C.; Schmidt, T.; Flaschel, E. (2003): Plasmid topology - An important factor influencing the performance of DNA drug delivery JOURNAL OF LIPOSOME RESEARCH,13:(1): 82-83.

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• [35]
  

  2003 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1610824

  Beshay, U.; Friehs, K.; Azzam, A. E. M.; Flaschel, E. (2003): Cultivation of Dictyostelium discoideum in immobilized form by colonization of porous supports PROCESS BIOCHEMISTRY,38:(11): 1521-1529.

  PUB | DOI | WoS
   
• [34]
  

  2003 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 1610932

  Schleef, M.; Voß, C.; Schmidt, T.; Flaschel, E. (2003): Plasmid vector stability in production, application and storage JOURNAL OF GENE MEDICINE,5:(3): S26-S26.

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• [33]
  

  2003 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1609656

  Voß, C.; Schmidt, T.; Schleef, M.; Friehs, K.; Flaschel, E. (2003): Production of supercoiled multimeric plasmid DNA for biopharmaceutical application JOURNAL OF BIOTECHNOLOGY,105:(3): 205-213.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [32]
  

  2003 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1609485

  Stephan, M.; Beshay, U.; Friehs, K.; Flaschel, E. (2003): Influence of medium composition on growth behaviour of Dictyostelium discoideum for cultivation on axenic media PROCESS BIOCHEMISTRY,39:(3): 333-343.

  PUB | DOI | WoS
   
• [31]
  

  2002 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1880734

  Schierl, F.; Friehs, K.; Risse, J. M.; Flaschel, E. (2002): Herstellung von Mediumskomponenten aus mikrobieller Biomasse Freiberger Forschungshefte,A 866: 112-124.

  PUB
   
• [30]
  

  2002 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 1613125

  Hettwer, J.; Oldenburg, H.; Flaschel, E. (2002): Enzymic routes to dihydroxyacetone phosphate or immediate precursors. In: Journal of Molecular Catalysis B: Enzymatic. ELSEVIER SCIENCE BV. (JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC, 19). S. 215-222.

  PUB | DOI | WoS
   
• [29]
  

  2002 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1613472

  Miksch, G.; Kleist, S.; Friehs, K.; Flaschel, E. (2002): Overexpression of the phytase from Escherichia coli and its extracellular production in bioreactors APPLIED MICROBIOLOGY AND BIOTECHNOLOGY,59:(6): 685-694.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [28]
  

  2001 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1880242

  Risse, J. M.; Friehs, K.; Flaschel, E. (2001): Recycling of Biomass Resulting from Fermentation Processes with Bacillus licheniformis Chem. Eng. Technol.,24:(10): 141-145.

  PUB
   
• [27]
  

  2001 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1616886

  Schroter, K.; Flaschel, E.; Pühler, A.; Becker, A. (2001): Xanthomonas campestris pv. campestris secretes the endoglucanases ENGXCA and ENGXCB: construction of an endoglucanase-deficient mutant for industrial xanthan production APPLIED MICROBIOLOGY AND BIOTECHNOLOGY,55:(6): 727-733.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [26]
  

  2001 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 1880243

  Miksch, G.; Flaschel, E. (2001): Secretion of homologous and heterologous recombinant proteins in Escherichia coli and other gram-negative bacteria by using a new secretion system. In: Otto-Wilhelm Merten; D. Mattanovich; C. Lang (Hrsg.): Recombinant protein production with prokaryotic and eukaryotic cells - A comparative view on host physiology. Selected articles from the meeting of the EFB Section on Microbial Physiology, Semmering, Austria, 5th-8th October 2000. Dordrecht: Kluwer Academic Publishers. S. 347-358.

  PUB
   
• [25]
  

  2000 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1619389

  Risse, J. M.; Friehs, K.; Flaschel, E. (2000): Biomasserückführung am Beispiel Bacillus licheniformis CHEMIE INGENIEUR TECHNIK,72:(7): 750-754.

  PUB | DOI | WoS
   
• [24]
  

  1999 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1621141

  Baier, R.; Schiene, K.; Kohring, B.; Flaschel, E.; Niehaus, K. (1999): Alfalfa and tobacco cells react differently to chitin oligosaccharides and Sinorhizobium meliloti nodulation factors PLANTA,210:(1): 157-164.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [23]
  

  1999 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1621612

  Schmidt, T.; Friehs, K.; Schleef, M.; Voß, C.; Flaschel, E. (1999): Quantitative analysis of plasmid forms by agarose and capillary gel electrophoresis ANALYTICAL BIOCHEMISTRY,274:(2): 235-240.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [22]
  

  1999 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1622862

  Miksch, G.; Neitzel, R.; Friehs, K.; Flaschel, E. (1999): High-level expression of a recombinant protein in Klebsiella planticola owing to induced secretion into the culture medium APPLIED MICROBIOLOGY AND BIOTECHNOLOGY,51:(5): 627-632.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [21]
  

  1998 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1625697

  Friehs, K.; Schierl, F.; Flaschel, E. (1998): Reprocessing of bacterial biomass for recycling as a medium component in fermentation processes CHEMIE INGENIEUR TECHNIK,70:(4): 435-437.

  PUB | DOI | WoS
   
• [20]
  

  1998 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1626311

  Margot, A.; Flaschel, E.; Renken, A. (1998): Development of a continuously operated reactor for the limited hydrolysis of whey protein by trypsin PROCESS BIOCHEMISTRY,33:(2): 125-131.

  PUB | DOI | WoS
   
• [19]
  

  1998 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1626283

  Huneke, F. U.; Flaschel, E. (1998): Behaviour of liquid/liquid/solid three-phase fixed bed reactors with application in biocatalysis JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY,71:(3): 213-222.

  PUB | DOI | WoS
   
• [18]
  

  1997 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1637759

  Miksch, G.; Neitzel, R.; Fiedler, E.; Friehs, K.; Flaschel, E. (1997): Extracellular production of a hybrid beta-glucanase from Bacillus by Escherichia coli under different cultivation conditions in shaking cultures and bioreactors APPLIED MICROBIOLOGY AND BIOTECHNOLOGY,47:(2): 120-126.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [17]
  

  1997 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1636857

  Miksch, G.; Fiedler, E.; Dobrowolski, P.; Flaschel, E. (1997): Controlled secretion into the culture medium of a hybrid beta-glucanase by Acetobacter methanolicus mediated by the kil gene of Escherichia coli located on a Tn5-derived transposon APPLIED MICROBIOLOGY AND BIOTECHNOLOGY,47:(5): 530-536.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [16]
  

  1997 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1628040

  Margot, A.; Flaschel, E.; Renken, A. (1997): Empirical kinetic models for tryptic whey-protein hydrolysis PROCESS BIOCHEMISTRY,32:(3): 217-223.

  PUB | DOI | WoS
   
• [15]
  

  1997 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1626566

  Kohring, B.; Baier, R.; Niehaus, K.; Pühler, A.; Flaschel, E. (1997): Production of nodulation factors by Rhizobium meliloti: fermentation, purification and characterization of glycolipids GLYCOCONJUGATE JOURNAL,14:(8): 963-971.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [14]
  

  1997 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1627108

  Poppenborg, L.; Friehs, K.; Flaschel, E. (1997): The green fluorescent protein is a versatile reporter for bioprocess monitoring JOURNAL OF BIOTECHNOLOGY,58:(2): 79-88.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [13]
  

  1996 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1638581

  Hentsch, M.; Warnery, P.; Renken, A.; Flaschel, E. (1996): Study of the simultaneous partitioning of proteins and surfactant in reverse micellar two-phase systems - Potential impact upon purification efficiency BIOSEPARATION,6:(2): 67-76.

  PUB | WoS
   
• [12]
  

  1996 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1628395

  Schmidt, T.; Friehs, K.; Flaschel, E. (1996): Rapid determination of plasmid copy number JOURNAL OF BIOTECHNOLOGY,49:(1-3): 219-229.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [11]
  

  1996 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 1639656

  Schmidt, T.; Friehs, K.; Flaschel, E. (1996): Plasmid copy number as a process variable for fermentation control. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY,211: 191-BIOT.

  PUB | WoS
   
• [10]
  

  1995 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1641313

  Flaschel, E.; Margot, A.; Dohmen, M.; Renken, A. (1995): Conversion-Space Time Profiles of Stirred-Tank Reactors Continuously Fed with Reactants and Catalyst under Conditions of Strong Catalyst Deactivation Chemical Engineering Science,50:(7): 1143-1147.

  PUB | DOI | WoS
   
• [9]
  

  1995 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1641188

  HENTSCH, M.; Flaschel, E.; RENKEN, A. (1995): RADIOLABELED AOT FOR STUDIES OF THE PARTITIONING OF THE SURFACTANT DURING PROTEIN EXTRACTION BY MEANS OF REVERSE MICELLAR 2-PHASE SYSTEMS JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY-ARTICLES,191:(1): 201-208.

  PUB | DOI | WoS
   
• [8]
  

  1994 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1644182

  MARGOT, A.; Flaschel, E.; RENKEN, A. (1994): CONTINUOUS MONITORING OF ENZYMATIC WHEY-PROTEIN HYDROLYSIS - CORRELATION OF BASE CONSUMPTION WITH SOLUBLE NITROGEN-CONTENT PROCESS BIOCHEMISTRY,29:(4): 257-262.

  PUB | DOI | WoS
   
• [7]
  

  1994 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1641804

  HUNEKE, F. U.; Flaschel, E. (1994): PHASE DISTRIBUTION IN LIQUID-LIQUID 3-PHASE FIXED-BED REACTORS CHEMIE INGENIEUR TECHNIK,66:(12): 1649-1651.

  PUB | DOI | WoS
   
• [6]
  

  1994 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 1643205

  Flaschel, E.; SCHAFFER, T. (1994): NEW EVIDENCE FOR DIMERIZATION-DEPENDENCE OF THE ACTIVITY OF CANDIDA-RUGOSA LIPASE. In: Biocatalysis. HARWOOD ACAD PUBL GMBH. (BIOCATALYSIS, 9). S. 241-248.

  PUB | DOI | WoS
   
• [5]
  

  1994 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1643820

  POPPENBORG, L.; Flaschel, E. (1994): AFFINITY EXTRACTION OF PROTEINS BY MEANS OF REVERSE MICELLAR PHASES CONTAINING A METAL-CHELATING SURFACTANT BIOTECHNOLOGY TECHNIQUES,8:(5): 307-312.

  PUB | DOI | WoS
   
• [4]
  

  1993 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1646173

  Flaschel, E.; Friehs, K. (1993): Improvement of downstream processing of recombinant proteins by means of genetic engineering Biotechnology Advances,11:(1): 31-77.

  PUB | PDF | DOI | WoS | PubMed | Europe PMC
   
• [3]
  

  1992 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1629782

  Hentsch, M.; Menoud, P.; Flaschel, E.; Renken, A. (1992): The effect of temperature on the kinetics of a reverse micellar protein extraction process BIOTECHNOLOGY TECHNIQUES,6:(5): 423-428.

  PUB | WoS
   
• [2]
  

  1992 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1629787

  Hentsch, M.; Menoud, P.; Steiner, L.; Flaschel, E.; Renken, A. (1992): Optimization of the surfactant (AOT) concentration in a reverse micellar extraction process BIOTECHNOLOGY TECHNIQUES,6:(4): 359-364.

  PUB | DOI | WoS
   
• [1]
  

  1992 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1647759

  MARGOT, A.; RICHOZ, C.; Flaschel, E.; RENKEN, A. (1992): INFLUENCE OF TRYPSIN DEACTIVATION ON THE HYDROLYSIS OF WHEY PROTEINS CHEMIE INGENIEUR TECHNIK,64:(6): 551-553.

  PUB | DOI | WoS