93 Publikationen

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  • [93]
    2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2904075
    J. Müller, J. M. Risse, D. Jussen, and E. Flaschel, “Development of fed-batch strategies for the production of streptavidin by Streptomyces avidinii based on power input and oxygen supply studies (vol 163, pg 325, 2013)”, JOURNAL OF BIOTECHNOLOGY, 2016, 226, 76-77.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [92]
    2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2906183
    F. Schulte, E. Flaschel, and K. Niehaus, “Proteome-Based Analysis of Colloidal Instability Enables the Detection of Haze-Active Proteins in Beer”, Journal of Agricultural and Food Chemistry, 2016, 64, 6752-6761.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [91]
    2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2903023
    D. Wetzel, J. Müller, E. Flaschel, K. Friehs, and J. M. Risse, “Fed-batch production and secretion of streptavidin by Hansenula polymorpha: Evaluation of genetic factors and bioprocess development”, JOURNAL OF BIOTECHNOLOGY, 2016, 225, 3-9.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [90]
    2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2906197
    J. Müller, S. Bruhn, E. Flaschel, K. Friehs, and J. M. Risse, “GAP promoter-based fed-batch production of highly bioactive core streptavidin by Pichia pastoris”, BIOTECHNOLOGY PROGRESS, 2016, 32, 855-864.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [89]
    2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2900637
    J. Müller, D. Wetzel, E. Flaschel, K. Friehs, and J. M. Risse, “Constitutive production and efficient secretion of soluble full-length streptavidin by an Escherichia coli 'leaky mutant'”, Journal of Biotechnology, 2016, 221, 91-100.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [88]
    2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2767378
    J. Müller, J. M. Risse, K. Friehs, and E. Flaschel, “Model-based development of an assay for the rapid detection of biotin-blocked binding sites of streptavidin”, Engineering in Life Sciences, 2015, 15, 627-639.
    PUB | DOI | WoS
     
  • [87]
    2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2759080
    P. Grimm, J. M. Risse, J. Müller, D. Cholewa, U. Beshay, K. Friehs, and E. Flaschel, “Applicability of Euglena gracilis for biorefineries demonstrated by the production of α-tocopherol and paramylon followed by anaerobic digestion”, Journal of Biotechnology, 2015, 215, 72-79.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [86]
    2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2722001
    J. P. Schwarzhans, D. Cholewa, P. Grimm, U. Beshay, J. M. Risse, K. Friehs, and E. Flaschel, “Dependency of the fatty acid composition of Euglena gracilis on growth phase and culture conditions”, Journal of Applied Phycology, 2015, 27, 1389-1399.
    PUB | DOI | WoS
     
  • [85]
    2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2679910 OA
    R. S. V. Selvamani, M. Telaar, K. Friehs, and E. Flaschel, “Antibiotic-free segregational plasmid stabilization in Escherichia coli owing to the knockout of triosephosphate isomerase (tpiA)”, Microbial Cell Factories, 2014, 13, : 58.
    PUB | PDF | DOI | WoS | PubMed | Europe PMC
     
  • [84]
    2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2675672
    R. S. V. Selvamani, K. Friehs, and E. Flaschel, “Extracellular recombinant protein production under continuous culture conditions with Escherichia coli using an alternative plasmid selection mechanism”, Bioprocess and Biosystems Engineering, 2014, 37, 401-413.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [83]
    2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2551139
    J. M. Müller, J. M. Risse, D. Jussen, and E. Flaschel, “Development of fed-batch strategies for the production of streptavidin by Streptomyces avidinii based on power input and oxygen supply studies”, Journal of Biotechnology, 2013, 163, 325-332.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [82]
    2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1945165
    C. Vijayendran, and E. Flaschel, “Impact of profiling technologies in the understanding of recombinant protein production”, Adv Biochem Eng Biotechnol, 2010, 121, 45-70.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [81]
    2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1929340
    S. Burgemeister, T. W. Nattkemper, T. Noll, R. Hoffrogge, and E. Flaschel, “CellViCAM-Cell viability classification for animal cell cultures using dark field micrographs”, JOURNAL OF BIOTECHNOLOGY, 2010, 149, 310-316.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [80]
    2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1796536
    B. Sommer, K. Friehs, and E. Flaschel, “Efficient production of extracellular proteins with Escherichia coli by means of optimized coexpression of bacteriocin release proteins”, JOURNAL OF BIOTECHNOLOGY, 2010, 145, 350-358.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [79]
    2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1795042
    B. Santek, M. Felski, K. Friehs, M. Lotz, and E. Flaschel, “Production of paramylon, a beta-1,3-glucan, by heterotrophic cultivation of Euglena gracilis on potato liquor”, ENGINEERING IN LIFE SCIENCES, 2010, 10, NA.
    PUB | DOI | WoS
     
  • [78]
    2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1588919
    M. Spexard, U. Beshay, J. M. Risse, G. Miksch, and E. Flaschel, “Screening for conditions of enhanced production of a recombinant beta-glucanase secreted into the medium by Escherichia coli”, BIOTECHNOLOGY LETTERS, 2010, 32, 243-248.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [77]
    2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1796749
    E. Flaschel, “Biocatalysis - New tasks, new approaches”, CHEMIE INGENIEUR TECHNIK, 2010, 82, 3.
    PUB | DOI | WoS
     
  • [76]
    2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1635287
    B. Santek, M. Felski, K. Friehs, M. Lotz, and E. Flaschel, “Production of paramylon, a beta-1,3-glucan, by heterotrophic cultivation of Euglena gracilis on a synthetic medium”, ENGINEERING IN LIFE SCIENCES, 2009, 9, 23-28.
    PUB | DOI | WoS
     
  • [75]
    2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1591533
    K. Tschapalda, N. Streitner, C. Voß, and E. Flaschel, “Generation of chromosomal DNA during alkaline lysis and removal by reverse micellar extraction”, APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2009, 84, 199-204.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [74]
    2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1636091
    U. Beshay, G. Miksch, K. Friehs, and E. Flaschel, “Integrated bioprocess for the production and purification of recombinant proteins by affinity chromatography in Escherichia coli”, BIOPROCESS AND BIOSYSTEMS ENGINEERING, 2009, 32, 149-158.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [73]
    2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1634165
    B. Sommer, K. Friehs, E. Flaschel, M. Reck, F. Stahl, and T. Scheper, “Extracellular production and affinity purification of recombinant proteins with Escherichia coli using the versatility of the maltose binding protein”, JOURNAL OF BIOTECHNOLOGY, 2009, 140, 194-202.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [72]
    2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1585399
    U. Beshay, K. Friehs, and E. Flaschel, “Growth of myxamoebae of the cellular slime mold Dictyostelium discoideum in suspension and immobilized form on living bacteria”, PROCESS BIOCHEMISTRY, 2008, 43, 1281-1287.
    PUB | DOI | WoS
     
  • [71]
    2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1585611 OA
    N. Wei, E. Flaschel, K. Friehs, and T. W. Nattkemper, “A machine vision system for automated non-invasive assessment of cell viability via dark field microscopy, wavelet feature selection and classification”, BMC Bioinformatics, 2008, 9, 449.
    PUB | PDF | DOI | WoS | PubMed | Europe PMC
     
  • [70]
    2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1587590 OA
    C. Vijayendran, A. Barsch, K. Friehs, K. Niehaus, A. Becker, and E. Flaschel, “Perceiving molecular evolution processes in Escherichia coli by comprehensive metabolite and gene expression profiling”, GENOME BIOLOGY, 2008, 9, R72.
    PUB | PDF | DOI | WoS | PubMed | Europe PMC
     
  • [69]
    2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1587283
    E. Flaschel, “Can we expect a breakthrough in downstream processing of biotechnological products in the near future?”, Chemical Engineering & Technology, 2008, 31, 809.
    PUB | DOI | WoS
     
  • [68]
    2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1587404
    E. Flaschel, “Renovation of biotechnological products - Faces a revolution?”, CHEMIE INGENIEUR TECHNIK, 2008, 80, 695.
    PUB | DOI | WoS
     
  • [67]
    2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1587409
    N. Streitner, C. Voß, and E. Flaschel, “Isolation of Plasmid-DNA by inverse micelles two phase system - Optimization of the reverse extraction”, CHEMIE INGENIEUR TECHNIK, 2008, 80, 831-837.
    PUB | DOI | WoS
     
  • [66]
    2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1585617
    G. Miksch, S. Ryu, J. M. Risse, and E. Flaschel, “Factors that influence the extracellular expression of streptavidin in Escherichia coli using a bacteriocin release protein”, APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2008, 81, 319-326.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [65]
    2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1631667 OA
    C. Vijayendran, S. Burgemeister, K. Friehs, K. Niehaus, and E. Flaschel, “2DBase: 2D-PAGE database of Escherichia coli”, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2007, 363, 822-827.
    PUB | PDF | DOI | WoS | PubMed | Europe PMC
     
  • [64]
    2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1594835
    C. Vijayendran, T. Polen, V. F. Wendisch, K. Friehs, K. Niehaus, and E. Flaschel, “The plasticity of global proteome and genome expression analyzed in closely related W3110 and MG1655 strains of a well-studied model organism, Escherichia coli-K12”, Journal of Biotechnology, 2007, 128, 747-761.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [63]
    2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1595739
    N. Wei, J. You, K. Friehs, E. Flaschel, and T. W. Nattkemper, “In situ dark field microscopy for on-line monitoring of yeast cultures”, BIOTECHNOLOGY LETTERS, 2007, 29, 373-378.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [62]
    2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1593120
    N. Wei, J. You, K. Friehs, E. Flaschel, and T. W. Nattkemper, “An in situ probe for on-line monitoring of cell density and viability on the basis of dark field microscopy in conjunction with image processing and supervised machine learning”, Biotechnology and Bioengineering, 2007, 97, 1489-1500.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [61]
    2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1632656
    N. Streitner, C. Voß, and E. Flaschel, “Reverse micellar extraction systems for the purification of pharmaceutical grade plasmid DNA”, JOURNAL OF BIOTECHNOLOGY, 2007, 131, 188-196.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [60]
    2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1593482
    U. Beshay, G. Miksch, K. Friehs, and E. Flaschel, “Improved beta-glucanase production by a recombinant Escherichia coli strain using a zinc-ion supplemented medium”, ENGINEERING IN LIFE SCIENCES, 2007, 7, 253-258.
    PUB | DOI | WoS
     
  • [59]
    2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1593326
    U. Beshay, G. Miksch, and E. Flaschel, “Improvement of a beta-glucanase activity test by taking into account the batch reactor balance of the test system”, BIOPROCESS AND BIOSYSTEMS ENGINEERING, 2007, 30, 251-259.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [58]
    2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1631107
    M. Blaesen, K. Friehs, and E. Flaschel, “Recycling of bacterial biomass in a process of L-threonine production by means of a recombinant strain of Escherichia coli”, JOURNAL OF BIOTECHNOLOGY, 2007, 132, 431-437.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [57]
    2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1631661
    U. Beshay, G. Miksch, K. Friehs, and E. Flaschel, “Increasing the secretion ability of the kil gene for recombinant proteins in Escherichia coli by using a strong stationary-phase promoter”, BIOTECHNOLOGY LETTERS, 2007, 29, 1893-1901.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [56]
    2006 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1599823
    E. Flaschel, and D. Hempel, “White biotechnology”, CHEMIE INGENIEUR TECHNIK, 2006, 78, 153.
    PUB | DOI | WoS
     
  • [55]
    2006 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 1599661
    E. Flaschel, in Engineering in Life Sciences, Wiley-Vch, 2006, p. 131-138.
    PUB | DOI | WoS
     
  • [54]
    2006 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1600329
    G. Miksch, F. Bettenworth, K. Friehs, E. Flaschel, A. Saalbach, and T. W. Nattkemper, “A rapid reporter system using GFP as a reporter protein for identification and screening of synthetic stationary-phase promoters in Escherichia coli”, APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2006, 70, 229-236.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [53]
    2006 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1597472
    M. Blaesen, E. Flaschel, and K. Friehs, “Sustainable production: Recycling of bacterial biomass resulting from a fermentation process with Klebsiella planticola”, CHEMICAL AND BIOCHEMICAL ENGINEERING QUARTERLY, 2006, 20, 263-268.
    PUB | WoS
     
  • [52]
    2006 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1599112
    C. Voß, D. Lindau, and E. Flaschel, “Production of recombinant RNase Ba and its application in downstream processing of plasmid DNA for pharmaceutical use”, BIOTECHNOLOGY PROGRESS, 2006, 22, 737-744.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [51]
    2005 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2906664
    T. Polen, V. F. Wendisch, K. Friehs, K. Niehaus, E. Flaschel, and C. Vijayendran, “The plasticity of global proteome and genome expression analysis in a well studied closely related model organism, Escherichia coli”, MOLECULAR & CELLULAR PROTEOMICS, 2005, 4, S248-S248.
    PUB | WoS
     
  • [50]
    2005 | Monographie | PUB-ID: 2714309
    F. Bettenworth, G. Miksch, K. Fries, E. Flaschel, A. Saalbach, J. Eickmeyer, and T. W. Nattkemper, An Online Monitoring System for the Screening of Stationary-Phase Promoters in E. Coli using GFP as a Reporter Protein, 2005.
    PUB
     
  • [49]
    2005 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1604386
    M. Arndt, S. Kleist, G. Miksch, K. Friehs, E. Flaschel, J. Trierweiler, and B. Hitzmann, “A feedforward-feedback substrate controller based on a Kalman filter for a fed-batch cultivation of Escherichia coli producing phytase”, COMPUTERS & CHEMICAL ENGINEERING, 2005, 29, 1113-1120.
    PUB | DOI | WoS
     
  • [48]
    2005 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1946602
    N. Wei, E. Flaschel, A. Saalbach, T. Twellmann, and T. W. Nattkemper, “Reagent-free automatic cell viability determination using neural networks based machine vision and dark-field microscopy in Saccharomyces cerevisiae”, Conf Proc IEEE Eng Med Biol Soc, 2005, 6, 6305-6308.
    PUB | DOI | PubMed | Europe PMC
     
  • [47]
    2005 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1601074
    G. Miksch, F. Bettenworth, K. Friehs, and E. Flaschel, “The sequence upstream of the -10 consensus sequence modulates the strength and induction time of stationary-phase promoters in Escherichia coli”, APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2005, 69, 312-320.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [46]
    2005 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 1601848
    G. Miksch, F. Bettenworth, K. Friehs, E. Flaschel, A. Saalbach, T. Twellmann, and T. W. Nattkemper, in Journal of Biotechnology, Elsevier Science Bv, 2005, p. 25-37.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [45]
    2005 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1604877
    J. M. Risse, A. Pühler, and E. Flaschel, “Production of N-acetyl-phosphinothricin: A substance used for inducing male sterility in transgenic plants”, ENGINEERING IN LIFE SCIENCES, 2005, 5, 38-45.
    PUB | DOI | WoS
     
  • [44]
    2005 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 1601124
    C. Vijayendran, T. Polen, V. Wendisch, K. Friehs, K. Niehaus, and E. Flaschel, “The plasticity of global proteome and genome expression analysis in a well studied closely related model organism, Escherichia coli”, Molecular & Cellular Proteomics, 2005, 4, S248.
    PUB | WoS
     
  • [43]
    2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1608845
    S. I. Han, K. Friehs, and E. Flaschel, “Cultivation of Dictyostelium discoideum on an improved synthetic medium in a conventional bioreactor”, PROCESS BIOCHEMISTRY, 2004, 39, 585-589.
    PUB | DOI | WoS
     
  • [42]
    2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1607969
    S. I. Han, K. Friehs, and E. Flaschel, “Improvement of a synthetic medium for Dictyostelium discoideum”, PROCESS BIOCHEMISTRY, 2004, 39, 925-930.
    PUB | DOI | WoS
     
  • [41]
    2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1609051
    C. Voß, T. Schmidt, M. Schleef, K. Friehs, and E. Flaschel, “Effect of ammonium chloride on plasmid DNA production in high cell density batch culture for biopharmaceutical use”, JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY, 2004, 79, 57-62.
    PUB | DOI | WoS
     
  • [40]
    2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1608382
    Y. H. Lu, J. C. Knol, M. H. K. Linskens, K. Friehs, P. J. M. van Haastert, and E. Flaschel, “Production of the soluble human Fas ligand by Dictyostelium discoideum cultivated on a synthetic medium”, JOURNAL OF BIOTECHNOLOGY, 2004, 108, 243-251.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [39]
    2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1606278
    Y. H. Lu, J. C. Knol, M. H. K. Linskens, K. Friehs, P. J. M. van Haastert, and E. Flaschel, “Cultivation of immobilized Dictyostelium discoideum for the production of soluble human Fas ligand”, APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2004, 65, 547-552.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [38]
    2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1606443
    Y. H. Lu, U. Beshay, K. Friehs, and E. Flaschel, “Mass production of Dictyostelium discoideum in homogenous and hetergeneous cultivation systems”, PROCESS BIOCHEMISTRY, 2004, 39, 1859-1870.
    PUB | DOI | WoS
     
  • [37]
    2003 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1609437
    U. Beshay, K. Friehs, A. E. M. Azzam, and E. Flaschel, “Analysis of the behaviour of Dictyostelium discoideum in immobilised state by means of continuous cultivation”, BIOPROCESS AND BIOSYSTEMS ENGINEERING, 2003, 26, 117-122.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [36]
    2003 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 1610736
    M. Schleef, C. Voß, T. Schmidt, and E. Flaschel, “Plasmid topology - An important factor influencing the performance of DNA drug delivery”, JOURNAL OF LIPOSOME RESEARCH, 2003, 13, 82-83.
    PUB | WoS
     
  • [35]
    2003 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1610824
    U. Beshay, K. Friehs, A. E. M. Azzam, and E. Flaschel, “Cultivation of Dictyostelium discoideum in immobilized form by colonization of porous supports”, PROCESS BIOCHEMISTRY, 2003, 38, 1521-1529.
    PUB | DOI | WoS
     
  • [34]
    2003 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 1610932
    M. Schleef, C. Voß, T. Schmidt, and E. Flaschel, “Plasmid vector stability in production, application and storage”, JOURNAL OF GENE MEDICINE, 2003, 5, S26-S26.
    PUB | WoS
     
  • [33]
    2003 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1609656
    C. Voß, T. Schmidt, M. Schleef, K. Friehs, and E. Flaschel, “Production of supercoiled multimeric plasmid DNA for biopharmaceutical application”, JOURNAL OF BIOTECHNOLOGY, 2003, 105, 205-213.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [32]
    2003 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1609485
    M. Stephan, U. Beshay, K. Friehs, and E. Flaschel, “Influence of medium composition on growth behaviour of Dictyostelium discoideum for cultivation on axenic media”, PROCESS BIOCHEMISTRY, 2003, 39, 333-343.
    PUB | DOI | WoS
     
  • [31]
    2002 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1880734
    F. Schierl, K. Friehs, J. M. Risse, and E. Flaschel, “Herstellung von Mediumskomponenten aus mikrobieller Biomasse”, Freiberger Forschungshefte, 2002, A 866, 112-124.
    PUB
     
  • [30]
    2002 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 1613125
    J. Hettwer, H. Oldenburg, and E. Flaschel, in Journal of Molecular Catalysis B: Enzymatic, Elsevier Science Bv, 2002, p. 215-222.
    PUB | DOI | WoS
     
  • [29]
    2002 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1613472
    G. Miksch, S. Kleist, K. Friehs, and E. Flaschel, “Overexpression of the phytase from Escherichia coli and its extracellular production in bioreactors”, APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2002, 59, 685-694.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [28]
    2001 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1880242
    J. M. Risse, K. Friehs, and E. Flaschel, “Recycling of Biomass Resulting from Fermentation Processes with Bacillus licheniformis”, Chem. Eng. Technol., 2001, 24, 141-145.
    PUB
     
  • [27]
    2001 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1616886
    K. Schroter, E. Flaschel, A. Pühler, and A. Becker, “Xanthomonas campestris pv. campestris secretes the endoglucanases ENGXCA and ENGXCB: construction of an endoglucanase-deficient mutant for industrial xanthan production”, APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2001, 55, 727-733.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [26]
    2001 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 1880243
    G. Miksch, and E. Flaschel, in Recombinant protein production with prokaryotic and eukaryotic cells - A comparative view on host physiology. Selected articles from the meeting of the EFB Section on Microbial Physiology, Semmering, Austria, 5th-8th October 2000 (Eds.: O.-W. Merten, D. Mattanovich, C. Lang), Kluwer Academic Publishers, Dordrecht, 2001, p. 347-358.
    PUB
     
  • [25]
    2000 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1619389
    J. M. Risse, K. Friehs, and E. Flaschel, “Biomasserückführung am Beispiel Bacillus licheniformis”, CHEMIE INGENIEUR TECHNIK, 2000, 72, 750-754.
    PUB | DOI | WoS
     
  • [24]
    1999 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1621141
    R. Baier, K. Schiene, B. Kohring, E. Flaschel, and K. Niehaus, “Alfalfa and tobacco cells react differently to chitin oligosaccharides and Sinorhizobium meliloti nodulation factors”, PLANTA, 1999, 210, 157-164.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [23]
    1999 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1621612
    T. Schmidt, K. Friehs, M. Schleef, C. Voß, and E. Flaschel, “Quantitative analysis of plasmid forms by agarose and capillary gel electrophoresis”, ANALYTICAL BIOCHEMISTRY, 1999, 274, 235-240.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [22]
    1999 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1622862
    G. Miksch, R. Neitzel, K. Friehs, and E. Flaschel, “High-level expression of a recombinant protein in Klebsiella planticola owing to induced secretion into the culture medium”, APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 1999, 51, 627-632.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [21]
    1998 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1625697
    K. Friehs, F. Schierl, and E. Flaschel, “Reprocessing of bacterial biomass for recycling as a medium component in fermentation processes”, CHEMIE INGENIEUR TECHNIK, 1998, 70, 435-437.
    PUB | DOI | WoS
     
  • [20]
    1998 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1626311
    A. Margot, E. Flaschel, and A. Renken, “Development of a continuously operated reactor for the limited hydrolysis of whey protein by trypsin”, PROCESS BIOCHEMISTRY, 1998, 33, 125-131.
    PUB | DOI | WoS
     
  • [19]
    1998 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1626283
    F. U. Huneke, and E. Flaschel, “Behaviour of liquid/liquid/solid three-phase fixed bed reactors with application in biocatalysis”, JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY, 1998, 71, 213-222.
    PUB | DOI | WoS
     
  • [18]
    1997 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1637759
    G. Miksch, R. Neitzel, E. Fiedler, K. Friehs, and E. Flaschel, “Extracellular production of a hybrid beta-glucanase from Bacillus by Escherichia coli under different cultivation conditions in shaking cultures and bioreactors”, APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 1997, 47, 120-126.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [17]
    1997 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1636857
    G. Miksch, E. Fiedler, P. Dobrowolski, and E. Flaschel, “Controlled secretion into the culture medium of a hybrid beta-glucanase by Acetobacter methanolicus mediated by the kil gene of Escherichia coli located on a Tn5-derived transposon”, APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 1997, 47, 530-536.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [16]
    1997 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1628040
    A. Margot, E. Flaschel, and A. Renken, “Empirical kinetic models for tryptic whey-protein hydrolysis”, PROCESS BIOCHEMISTRY, 1997, 32, 217-223.
    PUB | DOI | WoS
     
  • [15]
    1997 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1626566
    B. Kohring, R. Baier, K. Niehaus, A. Pühler, and E. Flaschel, “Production of nodulation factors by Rhizobium meliloti: fermentation, purification and characterization of glycolipids”, GLYCOCONJUGATE JOURNAL, 1997, 14, 963-971.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [14]
    1997 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1627108
    L. Poppenborg, K. Friehs, and E. Flaschel, “The green fluorescent protein is a versatile reporter for bioprocess monitoring”, JOURNAL OF BIOTECHNOLOGY, 1997, 58, 79-88.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [13]
    1996 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1638581
    M. Hentsch, P. Warnery, A. Renken, and E. Flaschel, “Study of the simultaneous partitioning of proteins and surfactant in reverse micellar two-phase systems - Potential impact upon purification efficiency”, BIOSEPARATION, 1996, 6, 67-76.
    PUB | WoS
     
  • [12]
    1996 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1628395
    T. Schmidt, K. Friehs, and E. Flaschel, “Rapid determination of plasmid copy number”, JOURNAL OF BIOTECHNOLOGY, 1996, 49, 219-229.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [11]
    1996 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 1639656
    T. Schmidt, K. Friehs, and E. Flaschel, “Plasmid copy number as a process variable for fermentation control.”, ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1996, 211, 191-BIOT.
    PUB | WoS
     
  • [10]
    1995 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1641313
    E. Flaschel, A. Margot, M. Dohmen, and A. Renken, “Conversion-Space Time Profiles of Stirred-Tank Reactors Continuously Fed with Reactants and Catalyst under Conditions of Strong Catalyst Deactivation”, Chemical Engineering Science, 1995, 50, 1143-1147.
    PUB | DOI | WoS
     
  • [9]
    1995 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1641188
    M. HENTSCH, E. Flaschel, and A. RENKEN, “RADIOLABELED AOT FOR STUDIES OF THE PARTITIONING OF THE SURFACTANT DURING PROTEIN EXTRACTION BY MEANS OF REVERSE MICELLAR 2-PHASE SYSTEMS”, JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY-ARTICLES, 1995, 191, 201-208.
    PUB | DOI | WoS
     
  • [8]
    1994 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1644182
    A. MARGOT, E. Flaschel, and A. RENKEN, “CONTINUOUS MONITORING OF ENZYMATIC WHEY-PROTEIN HYDROLYSIS - CORRELATION OF BASE CONSUMPTION WITH SOLUBLE NITROGEN-CONTENT”, PROCESS BIOCHEMISTRY, 1994, 29, 257-262.
    PUB | DOI | WoS
     
  • [7]
    1994 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1641804
    F. U. HUNEKE, and E. Flaschel, “PHASE DISTRIBUTION IN LIQUID-LIQUID 3-PHASE FIXED-BED REACTORS”, CHEMIE INGENIEUR TECHNIK, 1994, 66, 1649-1651.
    PUB | DOI | WoS
     
  • [6]
    1994 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 1643205
    E. Flaschel, and T. SCHAFFER, in Biocatalysis, Harwood Acad Publ Gmbh, 1994, p. 241-248.
    PUB | DOI | WoS
     
  • [5]
    1994 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1643820
    L. POPPENBORG, and E. Flaschel, “AFFINITY EXTRACTION OF PROTEINS BY MEANS OF REVERSE MICELLAR PHASES CONTAINING A METAL-CHELATING SURFACTANT”, BIOTECHNOLOGY TECHNIQUES, 1994, 8, 307-312.
    PUB | DOI | WoS
     
  • [4]
    1993 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1646173 OA
    E. Flaschel, and K. Friehs, “Improvement of downstream processing of recombinant proteins by means of genetic engineering”, Biotechnology Advances, 1993, 11, 31-77.
    PUB | PDF | DOI | WoS | PubMed | Europe PMC
     
  • [3]
    1992 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1629782
    M. Hentsch, P. Menoud, E. Flaschel, and A. Renken, “The effect of temperature on the kinetics of a reverse micellar protein extraction process”, BIOTECHNOLOGY TECHNIQUES, 1992, 6, 423-428.
    PUB | WoS
     
  • [2]
    1992 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1629787
    M. Hentsch, P. Menoud, L. Steiner, E. Flaschel, and A. Renken, “Optimization of the surfactant (AOT) concentration in a reverse micellar extraction process”, BIOTECHNOLOGY TECHNIQUES, 1992, 6, 359-364.
    PUB | DOI | WoS
     
  • [1]
    1992 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1647759
    A. MARGOT, C. RICHOZ, E. Flaschel, and A. RENKEN, “INFLUENCE OF TRYPSIN DEACTIVATION ON THE HYDROLYSIS OF WHEY PROTEINS”, CHEMIE INGENIEUR TECHNIK, 1992, 64, 551-553.
    PUB | DOI | WoS
     

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