57 Publikationen
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2023 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2969061Differential Effects of Rhodococcus equi Virulence-Associated Proteins on Macrophages and Artificial Lipid MembranesPUB | DOI | PubMed | Europe PMC
Hansen P, Haubenthal T, Reiter C, Kniewel J, Bosse-Plois K, Niemann H, von Bargen K, Haas A (2023)
Microbiology Spectrum : e0341722. -
2023 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2966452Enzymatic Late-Stage Halogenation of PeptidesPUB | DOI | WoS | PubMed | Europe PMC
Schnepel C, Moritzer A-C, Gäfe S, Montua N, Minges H, Nieß A, Niemann H, Sewald N (2023)
Chembiochem : a European journal of chemical biology 24(1): e202200569. -
2022 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2968195Regioselectivity and mechanism of enzymatic halogenation revisitedPUB | DOI | WoS
Niemann H (2022)
Chem Catalysis 2(10): 2408-2411. -
2022 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2963687
Direct interaction of a chaperone-bound type III secretion substrate with the export gatePUB | PDF | DOI | WoS | PubMed | Europe PMC
Gilzer D, Schreiner M, Niemann H (2022)
Nature Communications 13(1): 2858. -
2022 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2966836Crystals of SctV from different species reveal variable symmetry for the cytosolic domain of the type III secretion system export gatePUB | DOI | WoS | PubMed | Europe PMC
Gilzer D, Baum E, Lieske N, Kowal J, Niemann H (2022)
Acta Crystallographica Section F : Structural Biology Communications 78(11): 386-394. -
2022 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2961733A recurring packing contact in crystals of InlB pinpoints functional binding sites in the internalin domain and the B repeatPUB | DOI | WoS | PubMed | Europe PMC
Geerds C, Bleymüller WM, Meyer T, Widmann C, Niemann H (2022)
Acta Crystallographica Section D : Structural Biology 78( 3): 310-320. -
2021 | Sammelwerksbeitrag | Veröffentlicht | PUB-ID: 2954748Enzymatic halogenation: enzyme mining, mechanisms, and implementation in reaction cascadesPUB | DOI
Dachwitz S, Widmann C, Frese M, Niemann H, Sewald N (2021)
In: Amino Acids, Peptides and Proteins. Volume 44. Ryadnov M, Hudecz F (Eds); Amino Acids, Peptides And Proteins. Cambridge: Royal Society of Chemistry: 1-43. -
2021 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2956908
Conformational changes of loops highlight a potential binding site in Rhodococcus equi VapBPUB | PDF | DOI | WoS | PubMed | Europe PMC
Geerds C, Haas A, Niemann H (2021)
Acta crystallographica. Section F: Structural biology communications 77(Pt 8): 246-253. -
2020 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2950229
Not Cleaving the His-tag of Thal Results in More Tightly Packed and Better-Diffracting CrystalsPUB | PDF | DOI | Download (ext.) | WoS
Moritzer A-C, Prior T, Niemann H (2020)
Crystals 10(12): 1135. -
2020 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2945148
Structural Characterization of an S-enantioselective Imine Reductase from Mycobacterium SmegmatisPUB | PDF | DOI | WoS | PubMed | Europe PMC
Meyer T, Zumbrägel N, Geerds C, Gröger H, Niemann H (2020)
Biomolecules 10(8): 1130. -
2020 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2944738
Structure of apo flavin-dependent halogenase Xcc4156 hints at a reason for cofactor-soaking difficultiesPUB | PDF | DOI | WoS | PubMed | Europe PMC
Widmann C, Ismail M, Sewald N, Niemann H (2020)
Acta Crystallographica Section D Structural Biology 76(7): 687-697. -
2019 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2934121Structure-based switch of regioselectivity in the flavin-dependent tryptophan 6-halogenase ThalPUB | DOI | WoS | PubMed | Europe PMC
Moritzer A-C, Minges H, Prior T, Frese M, Sewald N, Niemann H (2019)
Journal of Biological Chemistry 294(7): 2529-2542. -
2019 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2938367
Binding of FAD and tryptophan to the tryptophan 6-halogenase Thal are negatively coupled.PUB | PDF | DOI | WoS | PubMed | Europe PMC
Moritzer A-C, Niemann H (2019)
Protein science 28(12): 2112-2118. -
2019 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2937628
Distinguishing Between Monomeric scFv and Diabody in Solution Using Light and Small Angle X-ray ScatteringPUB | PDF | DOI | WoS | PubMed | Europe PMC
Lüdel F, Bufe S, Bleymüller WM, de Jonge H de, Iamele L, Niemann H, Hellweg T (2019)
Antibodies 8(4): 48. -
2019 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2934796Inhibition of the MET Kinase Activity and Cell Growth in MET-Addicted Cancer Cells by Bi-Paratopic Linking.PUB | DOI | WoS | PubMed | Europe PMC
Andres F, Iamele L, Meyer T, Stuber JC, Kast F, Gherardi E, Niemann H, Pluckthun A (2019)
Journal of molecular biology 431(10): 2020-2039. -
2019 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2939444Competitive Binding Study Revealing the Influence of Fluorophore Labels on Biomolecular InteractionsPUB | DOI | WoS | PubMed | Europe PMC
Dietz MS, Wehrheim SS, Harwardt M-LIE, Niemann H, Heilemann M (2019)
NANO LETTERS 19(11): 8245-8249. -
2019 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2936258Specific high affinity interaction of Helicobacterpylori CagL with integrin alphaV beta6 promotes type IV secretion of CagA into human cells.PUB | DOI | WoS | PubMed | Europe PMC
Buß M, Tegtmeyer N, Schnieder J, Dong X, Li J, Springer TA, Backert S, Niemann H (2019)
The FEBS journal 286(20): 3980-3997. -
2019 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 2934621Met Receptor Tyrosine Kinase Activation Studied at the Single-Molecule LevelPUB | DOI | WoS
Dietz MS, Harwardt M-LIE, Wohland T, Niemann H, Heilemann M (2019)
In: BIOPHYSICAL JOURNAL., 116(3). Cambridge: Cell Press: 232A. -
2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2919984
A flavin-dependent halogenase from metagenomic analysis prefers bromination over chlorinationPUB | PDF | DOI | WoS | PubMed | Europe PMC
Neubauer P, Widmann C, Wibberg D, Schröder L, Frese M, Kottke T, Kalinowski J, Niemann H, Sewald N (2018)
PLoS ONE 13(5): e0196797. -
2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2920494Perfect merohedral twinning combined with noncrystallographic symmetry potentially causes the failure of molecular replacement with low-homology search models for the flavin-dependent halogenase HalX from Xanthomonas campestrisPUB | DOI | WoS | PubMed | Europe PMC
Buß M, Geerds C, Patschkowski T, Niehaus K, Niemann H (2018)
Acta Crystallographica Section F Structural Biology Communications 74(6): 345-350. -
2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2914444Membrane dynamics of resting and internalin B-bound MET receptor tyrosine kinase studied by single-molecule trackingPUB | DOI | WoS | PubMed | Europe PMC
Harwardt M-LIE, Young P, Bleymüller W, Meyer T, Karathanasis C, Niemann H, Heilemann M, Dietz MS (2017)
FEBS Open Bio 7(9): 1422-1440. -
2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2907323MET-activating Residues in the B-repeat of theListeria monocytogenesInvasion Protein InlBPUB | DOI | WoS | PubMed | Europe PMC
Bleymüller W, Lämmermann N, Ebbes M, Maynard D, Geerds C, Niemann H (2016)
Journal of Biological Chemistry 291(49): 25567-25577. -
2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2905854Crystal structure of Halobacterium salinarum halorhodopsin with a partially depopulated primary chloride-binding site.PUB | DOI | WoS | PubMed | Europe PMC
Schreiner M, Schlesinger R, Heberle J, Niemann H (2016)
Acta crystallographica. Section F, Structural biology communications 72(9): 692-699. -
2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2904685Live cell imaging shows hepatocyte growth factor-induced Met dimerizationPUB | DOI | WoS | PubMed | Europe PMC
Koschut D, Richert L, Pace G, Niemann H, Mely Y, Orian-Rousseau V (2016)
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH 1863(7): 1552-1558. -
2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2769481Direct binding of hepatocyte growth factor and vascular endothelial growth factor to CD44v6PUB | DOI | WoS | PubMed | Europe PMC
Volz Y, Koschut D, Matzke-Ogi A, Dietz MS, Karathanasis C, Richert L, Wagner MG, Mely Y, Heilemann M, Niemann H, Orian-Rousseau V (2015)
Bioscience Reports 35(4): e00236. -
2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2723568Adhesion of Several Cell Lines to Helicobacter pylori CagL Is Mediated by Integrin αVβ6 via an RGDLXXL MotifPUB | DOI | WoS | PubMed | Europe PMC
Barden S, Niemann H (2015)
Journal of Molecular Biology 427(6 Pt B): 1304-1315. -
2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2757969Structure of Halorhodopsin from Halobacterium salinarum in a new crystal form that imposes little restraint on the E-F loopPUB | DOI | WoS | PubMed | Europe PMC
Schreiner M, Schlesinger R, Heberle J, Niemann H (2015)
Journal of Structural Biology 190(3): 373-378. -
2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2685751Structure of Rhodococcus equi virulence-associated protein B (VapB) reveals an eight-stranded antiparallel β-barrel consisting of two Greek-key motifsPUB | DOI | WoS | PubMed | Europe PMC
Geerds C, Wohlmann J, Haas A, Niemann H (2014)
Acta crystallographica. Section F, Structural biology communications 70(Pt 7): 866-871. -
2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2671451
Crystal structure of an engineered YopM-InlB hybrid proteinPUB | PDF | DOI | WoS | PubMed | Europe PMC
Breitsprecher D, Gherardi E, Bleymüller W, Niemann H (2014)
BMC Structural Biology 14(1): 12. -
2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2673656Receptor-Ligand Interactions: Binding Affinities Studied by Single-Molecule and Super-Resolution Microscopy on Intact CellsPUB | DOI | WoS | PubMed | Europe PMC
Dietz MS, Fricke F, Krueger CL, Niemann H, Heilemann M (2014)
ChemPhysChem 15(4): 671-676. -
2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2673048Wound healing potential of a dimeric InlB variant analyzed by in vitro experiments on re-epithelialization of human skin modelsPUB | DOI | WoS | PubMed | Europe PMC
Kolditz F, Krausze J, Heinz DW, Niemann H, Müller-Goymann CC (2014)
European journal of pharmaceutics and biopharmaceutics 86(2: Theme Issue: Dermal and Transdermal Drug Delivery): 277-283. -
2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2676579Structure of a three-dimensional domain-swapped dimer of the Helicobacter pylori type IV secretion system pilus protein CagLPUB | DOI | WoS | PubMed | Europe PMC
Barden S, Schomburg B, Conradi J, Backert S, Sewald N, Niemann H (2014)
Acta crystallographica. Section D, Biological crystallography 70(Pt 5): 1391-1400. -
2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2607024Single-molecule photobleaching reveals increased MET receptor dimerization upon ligand binding in intact cellsPUB | DOI | WoS | PubMed | Europe PMC
Dietz MS, Haße D, Ferraris DM, Göhler A, Niemann H, Heilemann M (2013)
BMC biophysics 6(1): 6. -
2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2635833Structural basis of MET receptor dimerization by the bacterial invasion protein InlB and the HGF/SF splice variant NK1PUB | DOI | WoS | PubMed | Europe PMC
Niemann H (2013)
Biochimica Et Biophysica Acta (Bba) - Proteins & Proteomics 1834(10): 2195-2204. -
2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2637151A Helical RGD Motif Promoting Cell Adhesion: Crystal Structures of the Helicobacter pylori Type IV Secretion System Pilus Protein CagLPUB | DOI | WoS | PubMed | Europe PMC
Barden S, Lange S, Tegtmeyer N, Conradi J, Sewald N, Backert S, Niemann H (2013)
Structure (London, England : 1993) 21(11): 1931-1941. -
2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2520078
Crystal structure of the Yersinia enterocolitica type III secretion chaperone SycD in complex with a peptide of the minor translocator YopDPUB | PDF | DOI | WoS | PubMed | Europe PMC
Schreiner M, Niemann H (2012)
BMC Structural Biology 12(1): 13. -
2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2529531Engineered variants of InlB with an additional leucine-rich repeat discriminate between physiologically relevant and packing contacts in crystal structures of the InlB:MET complexPUB | DOI | WoS | PubMed | Europe PMC
Niemann H, Gherardi E, Bleymüller W, Heinz DW (2012)
Protein Science 21(10): 1528-1539. -
2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2352218Structural insights into Met receptor activationPUB | DOI | WoS | PubMed | Europe PMC
Niemann H (2011)
European Journal of Cell Biology 90(11): 972-981. -
2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2093288Fold and Function of the InlB B-repeatPUB | DOI | WoS | PubMed | Europe PMC
Ebbes M, Bleymüller W, Cernescu M, Noelker R, Brutschy B, Niemann H (2011)
Journal of Biological Chemistry 286(17): 15496-15506. -
2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2317316The unusual extended C-terminal helix of the peroxisomal alpha/beta-hydrolase Lpx1 is involved in dimer contacts but dispensable for dimerizationPUB | DOI | WoS | PubMed | Europe PMC
Thoms S, Hofhuis J, Thöing C, Gartner J, Niemann H (2011)
Journal of Structural Biology 175(3): 362-371. -
2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1796416Microdeletions within the hydrophobic core region of cellular prion protein alter its topology and metabolismPUB | DOI | WoS | PubMed | Europe PMC
Lutz J, Brabeck C, Niemann H, Kloz U, Korth C, Lingappa VR, Buerkle A (2010)
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 393(3): 439-444. -
2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1588661Ligand-Mediated Dimerization of the Met Receptor Tyrosine Kinase by the Bacterial Invasion Protein InlBPUB | DOI | WoS | PubMed | Europe PMC
Ferraris DM, Gherardi E, Di Y, Heinz DW, Niemann H (2010)
JOURNAL OF MOLECULAR BIOLOGY 395(3): 522-532. -
2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2444105Involvement of CD44v6 in InlB-dependent Listeria invasionPUB | DOI | WoS | PubMed | Europe PMC
Jung C, Matzke A, Niemann H, Schwerk C, Tenenbaum T, Orian-Rousseau V (2009)
Molecular Microbiology 72(5): 1196-1207. -
2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1592639Structure of the Yersinia enterocolitica type III secretion translocator chaperone SycDPUB | DOI | WoS | PubMed | Europe PMC
Buttner CR, Sorg I, Cornelis GR, Heinz DW, Niemann H (2008)
JOURNAL OF MOLECULAR BIOLOGY 375(4): 997-1012. -
2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1592014X-ray and neutron small-angle scattering analysis of the complex formed by the met receptor and the Listeria monocytogenes invasion protein InlBPUB | DOI | WoS | PubMed | Europe PMC
Niemann H, Petoukhov MV, Hartlein M, Moulin M, Gherardi E, Timmins P, Heinz DW, Svergun DI (2008)
JOURNAL OF MOLECULAR BIOLOGY 377(2): 489-500. -
2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1927887Lethal recessive myelin toxicity of prion protein lacking its central domainPUB | DOI | WoS | PubMed | Europe PMC
Baumann F, Tolnay M, Brabeck C, Pahnke J, Kloz U, Niemann H, Heikenwalder M, Rulicke T, Burkle A, Aguzzi A (2007)
EMBO J 26(2): 538-547. -
2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1927861Structure of the human receptor tyrosine kinase met in complex with the Listeria invasion protein InlBPUB | DOI | WoS | PubMed | Europe PMC
Niemann H, Jager V, Butler PJ, van den Heuvel J, Schmidt S, Ferraris D, Gherardi E, Heinz DW (2007)
Cell 130(2): 235-246. -
2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1927872Cdc42 and phosphoinositide 3-kinase drive Rac-mediated actin polymerization downstream of c-Met in distinct and common pathwaysPUB | DOI | WoS | PubMed | Europe PMC
Bosse T, Ehinger J, Czuchra A, Benesch S, Steffen A, Wu X, Schloen K, Niemann H, Scita G, Stradal TE, Brakebusch C, et al. (2007)
Mol Cell Biol 27(19): 6615-6628. -
2006 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1927900Barnase fusion as a tool to determine the crystal structure of the small disulfide-rich protein McoEeTIPUB | DOI | WoS | PubMed | Europe PMC
Niemann H, Schmoldt HU, Wentzel A, Kolmar H, Heinz DW (2006)
J Mol Biol 356(1): 1-8. -
2005 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1927908Crystal structure of Yersinia enterocolitica type III secretion chaperone SycTPUB | DOI | WoS | PubMed | Europe PMC
Buttner CR, Cornelis GR, Heinz DW, Niemann H (2005)
Protein Sci 14(8): 1993-2002. -
2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1927915Adhesins and invasins of pathogenic bacteria: a structural viewPUB | DOI | WoS | PubMed | Europe PMC
Niemann H, Schubert WD, Heinz DW (2004)
Microbes Infect 6(1): 101-112. -
2003 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1927921Aromatic amino acids at the surface of InlB are essential for host cell invasion by Listeria monocytogenesPUB | DOI | WoS | PubMed | Europe PMC
Machner MP, Frese S, Schubert WD, Orian-Rousseau V, Gherardi E, Wehland J, Niemann H, Heinz DW (2003)
Mol Microbiol 48(6): 1525-1536. -
2002 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1927932The dynamin A ring complex: molecular organization and nucleotide-dependent conformational changesPUB | DOI | WoS | PubMed | Europe PMC
Klockow B, Tichelaar W, Madden DR, Niemann H, Akiba T, Hirose K, Manstein DJ (2002)
EMBO J 21(3): 240-250. -
2001 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1927942Crystal structure of a dynamin GTPase domain in both nucleotide-free and GDP-bound formsPUB | DOI | WoS | PubMed | Europe PMC
Niemann H, Knetsch ML, Scherer A, Manstein DJ, Kull FJ (2001)
EMBO J 20(21): 5813-5821. -
1999 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1927950The nuclear distribution of Polycomb during Drosophila melanogaster development shown with a GFP fusion proteinPUB | DOI | WoS | PubMed | Europe PMC
Dietzel S, Niemann H, Bruckner B, Maurange C, Paro R (1999)
Chromosoma 108(2): 83-94. -
1997 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1927957Role of beta-turn residues in beta-hairpin formation and stability in designed peptidesPUB | DOI | WoS | PubMed | Europe PMC
Ramirez-Alvarado M, Blanco FJ, Niemann H, Serrano L (1997)
J Mol Biol 273(4): 898-912. -
1997 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1927964The formation of new nucleoli during macronuclear development of the hypotrichous ciliate Stylonychia lemnae visualized by in situ hybridizationPUB | DOI | WoS | PubMed | Europe PMC
Maercker C, Harjes P, Neben M, Niemann H, Sianidis G, Lipps HJ (1997)
Chromosome Res 5(5): 333-335.