Lethal recessive myelin toxicity of prion protein lacking its central domain

Baumann F, Tolnay M, Brabeck C, Pahnke J, Kloz U, Niemann H, Heikenwalder M, Rulicke T, Burkle A, Aguzzi A (2007)
EMBO J 26(2): 538-547.

Zeitschriftenaufsatz | Veröffentlicht | Englisch
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Baumann, F.; Tolnay, M.; Brabeck, C.; Pahnke, J.; Kloz, U.; Niemann, HartmutUniBi ; Heikenwalder, M.; Rulicke, T.; Burkle, A.; Aguzzi, A.
Transgenic; Models; Mice; Inbred DBA; Inbred C57BL; Recessive; Mice; Inbred C3H; Mice; Mice; Genes; Gene Deletion; Biological; Lethal; Genes; Animals; Mutant Proteins/physiology; Myelin Sheath/*metabolism; Protein Structure; Mice; PrPC Proteins/chemistry/*genetics/physiology; Tertiary; Survival Analysis
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Baumann F, Tolnay M, Brabeck C, et al. Lethal recessive myelin toxicity of prion protein lacking its central domain. EMBO J. 2007;26(2):538-547.
Baumann, F., Tolnay, M., Brabeck, C., Pahnke, J., Kloz, U., Niemann, H., Heikenwalder, M., et al. (2007). Lethal recessive myelin toxicity of prion protein lacking its central domain. EMBO J, 26(2), 538-547. https://doi.org/10.1038/sj.emboj.7601510
Baumann, F., Tolnay, M., Brabeck, C., Pahnke, J., Kloz, U., Niemann, Hartmut, Heikenwalder, M., Rulicke, T., Burkle, A., and Aguzzi, A. 2007. “Lethal recessive myelin toxicity of prion protein lacking its central domain”. EMBO J 26 (2): 538-547.
Baumann, F., Tolnay, M., Brabeck, C., Pahnke, J., Kloz, U., Niemann, H., Heikenwalder, M., Rulicke, T., Burkle, A., and Aguzzi, A. (2007). Lethal recessive myelin toxicity of prion protein lacking its central domain. EMBO J 26, 538-547.
Baumann, F., et al., 2007. Lethal recessive myelin toxicity of prion protein lacking its central domain. EMBO J, 26(2), p 538-547.
F. Baumann, et al., “Lethal recessive myelin toxicity of prion protein lacking its central domain”, EMBO J, vol. 26, 2007, pp. 538-547.
Baumann, F., Tolnay, M., Brabeck, C., Pahnke, J., Kloz, U., Niemann, H., Heikenwalder, M., Rulicke, T., Burkle, A., Aguzzi, A.: Lethal recessive myelin toxicity of prion protein lacking its central domain. EMBO J. 26, 538-547 (2007).
Baumann, F., Tolnay, M., Brabeck, C., Pahnke, J., Kloz, U., Niemann, Hartmut, Heikenwalder, M., Rulicke, T., Burkle, A., and Aguzzi, A. “Lethal recessive myelin toxicity of prion protein lacking its central domain”. EMBO J 26.2 (2007): 538-547.

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Rambold AS, Miesbauer M, Olschewski D, Seidel R, Riemer C, Smale L, Brumm L, Levy M, Gazit E, Oesterhelt D, Baier M, Becker CF, Engelhard M, Winklhofer KF, Tatzelt J., J Neurochem 107(1), 2008
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Prion protein lacks robust cytoprotective activity in cultured cells.
Christensen HM, Harris DA., Mol Neurodegener 3(), 2008
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The prion protein knockout mouse: a phenotype under challenge.
Steele AD, Lindquist S, Aguzzi A., Prion 1(2), 2007
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Bcl-2 overexpression delays caspase-3 activation and rescues cerebellar degeneration in prion-deficient mice that overexpress amino-terminally truncated prion.
Nicolas O, Gavín R, Braun N, Ureña JM, Fontana X, Soriano E, Aguzzi A, del Río JA., FASEB J 21(12), 2007
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Prion protein with an octapeptide insertion has impaired neuroprotective activity in transgenic mice.
Li A, Piccardo P, Barmada SJ, Ghetti B, Harris DA., EMBO J 26(11), 2007
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Doppel induces degeneration of cerebellar Purkinje cells independently of Bax.
Dong J, Li A, Yamaguchi N, Sakaguchi S, Harris DA., Am J Pathol 171(2), 2007
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Insights into prion strains and neurotoxicity.
Aguzzi A, Heikenwalder M, Polymenidou M., Nat Rev Mol Cell Biol 8(7), 2007
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In vitro and in vivo neurotoxicity of prion protein oligomers.
Simoneau S, Rezaei H, Salès N, Kaiser-Schulz G, Lefebvre-Roque M, Vidal C, Fournier JG, Comte J, Wopfner F, Grosclaude J, Schätzl H, Lasmézas CI., PLoS Pathog 3(8), 2007
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The CNS glycoprotein Shadoo has PrP(C)-like protective properties and displays reduced levels in prion infections.
Watts JC, Drisaldi B, Ng V, Yang J, Strome B, Horne P, Sy MS, Yoong L, Young R, Mastrangelo P, Bergeron C, Fraser PE, Carlson GA, Mount HT, Schmitt-Ulms G, Westaway D., EMBO J 26(17), 2007
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Prions and peripheral nerves: a deadly rendezvous.
Heikenwalder M, Julius C, Aguzzi A., J Neurosci Res 85(12), 2007
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Neurotoxic species in prion disease: a role for PrP isoforms?
Harrison CF, Barnham KJ, Hill AF., J Neurochem 103(5), 2007
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