32 Publikationen
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2023 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2981179E-64c-hydrazide based cathepsin C inhibitors: Optimizing the interactions with the S1'-S2' areaPUB | PDF | DOI | WoS | PubMed | Europe PMC
Tromsdorf, Nora, E-64c-hydrazide based cathepsin C inhibitors: Optimizing the interactions with the S1'-S2' area. ChemMedChem (). , 2023 -
2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2703442Selective Targeting of Tumor and Stromal Cells By a Nanocarrier System Displaying Lipidated Cathepsin B InhibitorPUB | DOI | WoS | PubMed | Europe PMC
Mikhaylov, G., Selective Targeting of Tumor and Stromal Cells By a Nanocarrier System Displaying Lipidated Cathepsin B Inhibitor. Angewandte Chemie International Edition 53 (38). , 2014 -
2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2699425The activity and localization patterns of cathepsins B and X in cells of the mouse gastrointestinal tract differ along its lengthPUB | DOI | WoS | PubMed | Europe PMC
Tamhane, Tripti, The activity and localization patterns of cathepsins B and X in cells of the mouse gastrointestinal tract differ along its length. Biological Chemistry 395 (10). , 2014 -
2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2622177E-64c-Hydrazide: A Lead Structure for the Development of Irreversible CathepsinC InhibitorsPUB | DOI | WoS | PubMed | Europe PMC
Radzey, Hanna, E-64c-Hydrazide: A Lead Structure for the Development of Irreversible CathepsinC Inhibitors. Chemmedchem 8 (8). , 2013 -
2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2489346Substrate specificity of Staphylococcus aureus cysteine proteases - Staphopains A, B and CPUB | DOI | WoS | PubMed | Europe PMC
Kalinska, Magdalena, Substrate specificity of Staphylococcus aureus cysteine proteases - Staphopains A, B and C. Biochimie 94 (2). , 2012 -
2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2489135Activation of the Nipah Virus Fusion Protein in MDCK Cells Is Mediated by Cathepsin B within the Endosome-Recycling CompartmentPUB | DOI | WoS | PubMed | Europe PMC
Diederich, Sandra, Activation of the Nipah Virus Fusion Protein in MDCK Cells Is Mediated by Cathepsin B within the Endosome-Recycling Compartment. Journal of Virology 86 (7). , 2012 -
2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2454769The arginine mimicking beta-amino acid beta(3)hPhe(3-H(2)N-CH(2)) as S1 ligand in cyclotheonamide-based beta-tryptase inhibitorsPUB | DOI | WoS | PubMed | Europe PMC
Janke, Dennis, The arginine mimicking beta-amino acid beta(3)hPhe(3-H(2)N-CH(2)) as S1 ligand in cyclotheonamide-based beta-tryptase inhibitors. Bioorganic & Medicinal Chemistry 19 (23). , 2011 -
2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403684Aziridine-2,3-Dicarboxylate-Based Cysteine Cathepsin Inhibitors Induce Cell Death in Leishmania major Associated with Accumulation of Debris in Autophagy-Related Lysosome-Like VacuolesPUB | DOI | WoS | PubMed | Europe PMC
Schurigt, Uta, Aziridine-2,3-Dicarboxylate-Based Cysteine Cathepsin Inhibitors Induce Cell Death in Leishmania major Associated with Accumulation of Debris in Autophagy-Related Lysosome-Like Vacuoles. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 54 (12). , 2010 -
2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403708Upgrading a Natural Product: Inhibition of Human beta-Tryptase by Cyclotheonamide AnaloguesPUB | DOI | WoS | PubMed | Europe PMC
Schaschke, Norbert, Upgrading a Natural Product: Inhibition of Human beta-Tryptase by Cyclotheonamide Analogues. CHEMMEDCHEM 5 (3). , 2010 -
2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403720Inhibition of human mu-calpain by conformationally constrained calpastatin peptidesPUB | DOI | WoS | PubMed | Europe PMC
Pfizer, Jose, Inhibition of human mu-calpain by conformationally constrained calpastatin peptides. BIOLOGICAL CHEMISTRY 389 (1). , 2008 -
2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403715Inhibition of cathepsin L by epoxysuccinyl peptides simultaneously addressing active-site and remote-site regionsPUB | DOI | WoS | PubMed | Europe PMC
Schaschke, Norbert, Inhibition of cathepsin L by epoxysuccinyl peptides simultaneously addressing active-site and remote-site regions. CHEMBIOCHEM 9 (11). , 2008 -
2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403726Cathepsin B is essential for regeneration of scratch-wounded normal human epidermal keratinocytesPUB | DOI | WoS | PubMed | Europe PMC
Bueth, Heiko, Cathepsin B is essential for regeneration of scratch-wounded normal human epidermal keratinocytes. EUROPEAN JOURNAL OF CELL BIOLOGY 86 (11-12). , 2007 -
2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403747Mast cell tryptase beta as a target in allergic inflammation: An evolving storyPUB | DOI | WoS | PubMed | Europe PMC
Sommerhoff, C. P., Mast cell tryptase beta as a target in allergic inflammation: An evolving story. CURRENT PHARMACEUTICAL DESIGN 13 (3). , 2007 -
2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403737Primed-site probing of papain-like cysteine proteasesPUB | DOI | WoS
Pfizer, Jose Maria, Primed-site probing of papain-like cysteine proteases. INTERNATIONAL JOURNAL OF PEPTIDE RESEARCH AND THERAPEUTICS 13 (1-2). , 2007 -
2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403744(2S,3S)-Oxirane-2,3-dicarboxylic acid: A privileged platform for probing human cysteine cathepsinsPUB | DOI | WoS | PubMed | Europe PMC
Schaschke, Norbert, (2S,3S)-Oxirane-2,3-dicarboxylic acid: A privileged platform for probing human cysteine cathepsins. JOURNAL OF BIOTECHNOLOGY 129 (2). , 2007 -
2005 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403754Affinity chromatography of tryptases: Design, synthesis and characterization of a novel matrix-bound bivalent inhibitorPUB | DOI | WoS | PubMed | Europe PMC
Schaschke, Norbert, Affinity chromatography of tryptases: Design, synthesis and characterization of a novel matrix-bound bivalent inhibitor. CHEMBIOCHEM 6 (1). , 2005 -
2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403774Crystal structure of NS-134 in complex with bovine cathepsin B: a two-headed epoxysuccinyl inhibitor extends along the entire active-site cleftPUB | DOI | WoS | PubMed | Europe PMC
Stern, I, Crystal structure of NS-134 in complex with bovine cathepsin B: a two-headed epoxysuccinyl inhibitor extends along the entire active-site cleft. BIOCHEMICAL JOURNAL 381 (2). , 2004 -
2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403779Conformational and molecular modeling studies of beta-cyclodextrin-heptagastrin and the third extracellular loop of the cholecystokinin 2 receptorPUB | DOI | WoS | PubMed | Europe PMC
Giragossian, C, Conformational and molecular modeling studies of beta-cyclodextrin-heptagastrin and the third extracellular loop of the cholecystokinin 2 receptor. BIOCHEMISTRY 43 (10). , 2004 -
2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403785Miraziridine A: natures blueprint towards protease class-spanning inhibitorsPUB | DOI | WoS | PubMed | Europe PMC
Schaschke, Norbert, Miraziridine A: natures blueprint towards protease class-spanning inhibitors. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 14 (4). , 2004 -
2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403760HaCaT keratinocytes secrete lysosomal cysteine proteinases during migrationPUB | DOI | WoS | PubMed | Europe PMC
Buth, H, HaCaT keratinocytes secrete lysosomal cysteine proteinases during migration. EUROPEAN JOURNAL OF CELL BIOLOGY 83 (11-12). , 2004 -
2003 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403798Calpastatin exon 1B-derived peptide, a selective inhibitor of calpain: Enhancing cell permeability by conjugation with penetratinPUB | DOI | WoS | PubMed | Europe PMC
Gil-Parrado, S, Calpastatin exon 1B-derived peptide, a selective inhibitor of calpain: Enhancing cell permeability by conjugation with penetratin. BIOLOGICAL CHEMISTRY 384 (3). , 2003 -
2002 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403813Surface cathepsin B protects cytotoxic lymphocytes from self-destruction after degranulationPUB | DOI | WoS | PubMed | Europe PMC
Balaji, KN, Surface cathepsin B protects cytotoxic lymphocytes from self-destruction after degranulation. JOURNAL OF EXPERIMENTAL MEDICINE 196 (4). , 2002 -
2002 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403820Epoxysuccinyl peptide-derived cathepsin B inhibitors: Modulating membrane permeability by conjugation with the C-terminal heptapeptide segment of penetratinPUB | DOI | WoS | PubMed | Europe PMC
Schaschke, Norbert, Epoxysuccinyl peptide-derived cathepsin B inhibitors: Modulating membrane permeability by conjugation with the C-terminal heptapeptide segment of penetratin. BIOLOGICAL CHEMISTRY 383 (5). , 2002 -
2002 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403828Bivalent inhibition of beta-tryptase: Distance scan of neighboring subunits by dibasic inhibitorsPUB | DOI | WoS | PubMed | Europe PMC
Schaschke, Norbert, Bivalent inhibition of beta-tryptase: Distance scan of neighboring subunits by dibasic inhibitors. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 12 (6). , 2002 -
2001 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403834Bivalent inhibition of human beta-tryptasePUB | DOI | WoS | PubMed | Europe PMC
Schaschke, Norbert, Bivalent inhibition of human beta-tryptase. CHEMISTRY & BIOLOGY 8 (4). , 2001 -
2000 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403844Epoxysuccinyl peptide-derived affinity labels for cathepsin BPUB | DOI | WoS | PubMed | Europe PMC
Schaschke, Norbert, Epoxysuccinyl peptide-derived affinity labels for cathepsin B. FEBS LETTERS 482 (1-2). , 2000 -
2000 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403852beta-cyclodextrin/epoxysuccinyl peptide conjugates: new drug targeting system for tumor cellsPUB | DOI | WoS | PubMed | Europe PMC
Schaschke, Norbert, beta-cyclodextrin/epoxysuccinyl peptide conjugates: new drug targeting system for tumor cells. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 10 (7). , 2000 -
1998 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403860Cyclodextrin as carrier of peptide hormones. Conformational and biological properties of beta-cyclodextrin/gastrin constructsPUB | DOI | WoS
Schaschke, Norbert, Cyclodextrin as carrier of peptide hormones. Conformational and biological properties of beta-cyclodextrin/gastrin constructs. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 120 (28). , 1998 -
1998 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403869Substrate/propeptide-derived endo-epoxysuccinyl peptides as highly potent and selective cathepsin B inhibitorsPUB | DOI | WoS | PubMed | Europe PMC
Schaschke, Norbert, Substrate/propeptide-derived endo-epoxysuccinyl peptides as highly potent and selective cathepsin B inhibitors. FEBS LETTERS 421 (1). , 1998 -
1997 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403875Oligopresentation of protease inhibitors with beta-cyclodextrin as templatePUB | DOI | WoS
Schaschke, Norbert, Oligopresentation of protease inhibitors with beta-cyclodextrin as template. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 7 (19). , 1997 -
1997 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403882E-64 analogues as inhibitors of cathepsin B. On the role of the absolute configuration of the epoxysuccinyl groupPUB | DOI | WoS | PubMed | Europe PMC
Schaschke, Norbert, E-64 analogues as inhibitors of cathepsin B. On the role of the absolute configuration of the epoxysuccinyl group. BIOORGANIC & MEDICINAL CHEMISTRY 5 (9). , 1997 -
1996 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403889Cyclodextrins as templates for the presentation of protease inhibitorsPUB | DOI | WoS | PubMed | Europe PMC
Schaschke, Norbert, Cyclodextrins as templates for the presentation of protease inhibitors. FEBS LETTERS 391 (3). , 1996