32 Publikationen

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  • [32]
    2023 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2981179 OA
    Tromsdorf, N., et al., 2023. E-64c-hydrazide based cathepsin C inhibitors: Optimizing the interactions with the S1'-S2' area. ChemMedChem, : e202300218.
    PUB | PDF | DOI | WoS | PubMed | Europe PMC
     
  • [31]
    2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2703442
    Mikhaylov, G., et al., 2014. Selective Targeting of Tumor and Stromal Cells By a Nanocarrier System Displaying Lipidated Cathepsin B Inhibitor. Angewandte Chemie International Edition, 53(38), p 10077-10081.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [30]
    2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2699425
    Tamhane, T., et al., 2014. The activity and localization patterns of cathepsins B and X in cells of the mouse gastrointestinal tract differ along its length. Biological Chemistry, 395(10), p 1201-1219.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [29]
    2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2622177
    Radzey, H., et al., 2013. E-64c-Hydrazide: A Lead Structure for the Development of Irreversible CathepsinC Inhibitors. Chemmedchem, 8(8), p 1314-1321.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [28]
    2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2489346
    Kalinska, M., et al., 2012. Substrate specificity of Staphylococcus aureus cysteine proteases - Staphopains A, B and C. Biochimie, 94(2), p 318-327.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [27]
    2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2489135
    Diederich, S., et al., 2012. Activation of the Nipah Virus Fusion Protein in MDCK Cells Is Mediated by Cathepsin B within the Endosome-Recycling Compartment. Journal of Virology, 86(7), p 3736-3745.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [26]
    2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2454769
    Janke, D., Sommerhoff, C.P., & Schaschke, N., 2011. The arginine mimicking beta-amino acid beta(3)hPhe(3-H(2)N-CH(2)) as S1 ligand in cyclotheonamide-based beta-tryptase inhibitors. Bioorganic & Medicinal Chemistry, 19(23), p 7236-7243.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [25]
    2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403684
    Schurigt, U., et al., 2010. Aziridine-2,3-Dicarboxylate-Based Cysteine Cathepsin Inhibitors Induce Cell Death in Leishmania major Associated with Accumulation of Debris in Autophagy-Related Lysosome-Like Vacuoles. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 54(12), p 5028-5041.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [24]
    2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403708
    Schaschke, N., & Sommerhoff, C.P., 2010. Upgrading a Natural Product: Inhibition of Human beta-Tryptase by Cyclotheonamide Analogues. CHEMMEDCHEM, 5(3), p 367-370.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [23]
    2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403720
    Pfizer, J., et al., 2008. Inhibition of human mu-calpain by conformationally constrained calpastatin peptides. BIOLOGICAL CHEMISTRY, 389(1), p 83-90.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [22]
    2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403715
    Schaschke, N., Assfalg-Machleidt, I., & Machleidt, W., 2008. Inhibition of cathepsin L by epoxysuccinyl peptides simultaneously addressing active-site and remote-site regions. CHEMBIOCHEM, 9(11), p 1721-1724.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [21]
    2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403726
    Bueth, H., et al., 2007. Cathepsin B is essential for regeneration of scratch-wounded normal human epidermal keratinocytes. EUROPEAN JOURNAL OF CELL BIOLOGY, 86(11-12), p 747-761.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [20]
    2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403747
    Sommerhoff, C.P., & Schaschke, N., 2007. Mast cell tryptase beta as a target in allergic inflammation: An evolving story. CURRENT PHARMACEUTICAL DESIGN, 13(3), p 313-332.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [19]
    2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403737
    Pfizer, J.M., et al., 2007. Primed-site probing of papain-like cysteine proteases. INTERNATIONAL JOURNAL OF PEPTIDE RESEARCH AND THERAPEUTICS, 13(1-2), p 93-104.
    PUB | DOI | WoS
     
  • [18]
    2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403744
    Schaschke, N., 2007. (2S,3S)-Oxirane-2,3-dicarboxylic acid: A privileged platform for probing human cysteine cathepsins. JOURNAL OF BIOTECHNOLOGY, 129(2), p 308-315.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [17]
    2005 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403754
    Schaschke, N., et al., 2005. Affinity chromatography of tryptases: Design, synthesis and characterization of a novel matrix-bound bivalent inhibitor. CHEMBIOCHEM, 6(1), p 95-103.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [16]
    2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403774
    Stern, I., et al., 2004. Crystal structure of NS-134 in complex with bovine cathepsin B: a two-headed epoxysuccinyl inhibitor extends along the entire active-site cleft. BIOCHEMICAL JOURNAL, 381(2), p 511-517.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [15]
    2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403779
    Giragossian, C., et al., 2004. Conformational and molecular modeling studies of beta-cyclodextrin-heptagastrin and the third extracellular loop of the cholecystokinin 2 receptor. BIOCHEMISTRY, 43(10), p 2724-2731.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [14]
    2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403785
    Schaschke, N., 2004. Miraziridine A: natures blueprint towards protease class-spanning inhibitors. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 14(4), p 855-857.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [13]
    2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403760
    Buth, H., et al., 2004. HaCaT keratinocytes secrete lysosomal cysteine proteinases during migration. EUROPEAN JOURNAL OF CELL BIOLOGY, 83(11-12), p 781-795.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [12]
    2003 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403798
    Gil-Parrado, S., et al., 2003. Calpastatin exon 1B-derived peptide, a selective inhibitor of calpain: Enhancing cell permeability by conjugation with penetratin. BIOLOGICAL CHEMISTRY, 384(3), p 395-402.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [11]
    2002 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403813
    Balaji, K.N., et al., 2002. Surface cathepsin B protects cytotoxic lymphocytes from self-destruction after degranulation. JOURNAL OF EXPERIMENTAL MEDICINE, 196(4), p 493-503.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [10]
    2002 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403820
    Schaschke, N., et al., 2002. Epoxysuccinyl peptide-derived cathepsin B inhibitors: Modulating membrane permeability by conjugation with the C-terminal heptapeptide segment of penetratin. BIOLOGICAL CHEMISTRY, 383(5), p 849-852.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [9]
    2002 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403828
    Schaschke, N., et al., 2002. Bivalent inhibition of beta-tryptase: Distance scan of neighboring subunits by dibasic inhibitors. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 12(6), p 985-988.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [8]
    2001 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403834
    Schaschke, N., et al., 2001. Bivalent inhibition of human beta-tryptase. CHEMISTRY & BIOLOGY, 8(4), p 313-327.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [7]
    2000 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403844
    Schaschke, N., et al., 2000. Epoxysuccinyl peptide-derived affinity labels for cathepsin B. FEBS LETTERS, 482(1-2), p 91-96.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [6]
    2000 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403852
    Schaschke, N., et al., 2000. beta-cyclodextrin/epoxysuccinyl peptide conjugates: new drug targeting system for tumor cells. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 10(7), p 677-680.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [5]
    1998 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403860
    Schaschke, N., et al., 1998. Cyclodextrin as carrier of peptide hormones. Conformational and biological properties of beta-cyclodextrin/gastrin constructs. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 120(28), p 7030-7038.
    PUB | DOI | WoS
     
  • [4]
    1998 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403869
    Schaschke, N., et al., 1998. Substrate/propeptide-derived endo-epoxysuccinyl peptides as highly potent and selective cathepsin B inhibitors. FEBS LETTERS, 421(1), p 80-82.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [3]
    1997 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403875
    Schaschke, N., et al., 1997. Oligopresentation of protease inhibitors with beta-cyclodextrin as template. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 7(19), p 2507-2512.
    PUB | DOI | WoS
     
  • [2]
    1997 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403882
    Schaschke, N., et al., 1997. E-64 analogues as inhibitors of cathepsin B. On the role of the absolute configuration of the epoxysuccinyl group. BIOORGANIC & MEDICINAL CHEMISTRY, 5(9), p 1789-1797.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [1]
    1996 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403889
    Schaschke, N., et al., 1996. Cyclodextrins as templates for the presentation of protease inhibitors. FEBS LETTERS, 391(3), p 297-301.
    PUB | DOI | WoS | PubMed | Europe PMC
     

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