Surface cathepsin B protects cytotoxic lymphocytes from self-destruction after degranulation

Balaji KN, Schaschke N, Machleidt W, Catalfamo M, Henkart PA (2002)
JOURNAL OF EXPERIMENTAL MEDICINE 196(4): 493-503.

Zeitschriftenaufsatz | Veröffentlicht | Englisch
 
Download
Es wurden keine Dateien hochgeladen. Nur Publikationsnachweis!
DOI
Autor*in
Balaji, KN; Schaschke, NorbertUniBi; Machleidt, W; Catalfamo, M; Henkart, PA
Einrichtung
Fakultät für Chemie > Organische Chemie III
Erscheinungsjahr
2002
Zeitschriftentitel
JOURNAL OF EXPERIMENTAL MEDICINE
Band
196
Ausgabe
4
Seite(n)
493-503
ISSN
0022-1007
eISSN
1540-9538
Page URI
https://pub.uni-bielefeld.de/record/2403813

Zitieren

Balaji KN, Schaschke N, Machleidt W, Catalfamo M, Henkart PA. Surface cathepsin B protects cytotoxic lymphocytes from self-destruction after degranulation. JOURNAL OF EXPERIMENTAL MEDICINE. 2002;196(4):493-503.
Balaji, K. N., Schaschke, N., Machleidt, W., Catalfamo, M., & Henkart, P. A. (2002). Surface cathepsin B protects cytotoxic lymphocytes from self-destruction after degranulation. JOURNAL OF EXPERIMENTAL MEDICINE, 196(4), 493-503. https://doi.org/10.1084/jem.20011836
Balaji, KN, Schaschke, Norbert, Machleidt, W, Catalfamo, M, and Henkart, PA. 2002. “Surface cathepsin B protects cytotoxic lymphocytes from self-destruction after degranulation”. JOURNAL OF EXPERIMENTAL MEDICINE 196 (4): 493-503.
Balaji, K. N., Schaschke, N., Machleidt, W., Catalfamo, M., and Henkart, P. A. (2002). Surface cathepsin B protects cytotoxic lymphocytes from self-destruction after degranulation. JOURNAL OF EXPERIMENTAL MEDICINE 196, 493-503.
Balaji, K.N., et al., 2002. Surface cathepsin B protects cytotoxic lymphocytes from self-destruction after degranulation. JOURNAL OF EXPERIMENTAL MEDICINE, 196(4), p 493-503.
K.N. Balaji, et al., “Surface cathepsin B protects cytotoxic lymphocytes from self-destruction after degranulation”, JOURNAL OF EXPERIMENTAL MEDICINE, vol. 196, 2002, pp. 493-503.
Balaji, K.N., Schaschke, N., Machleidt, W., Catalfamo, M., Henkart, P.A.: Surface cathepsin B protects cytotoxic lymphocytes from self-destruction after degranulation. JOURNAL OF EXPERIMENTAL MEDICINE. 196, 493-503 (2002).
Balaji, KN, Schaschke, Norbert, Machleidt, W, Catalfamo, M, and Henkart, PA. “Surface cathepsin B protects cytotoxic lymphocytes from self-destruction after degranulation”. JOURNAL OF EXPERIMENTAL MEDICINE 196.4 (2002): 493-503.

97 Zitationen in Europe PMC

Daten bereitgestellt von Europe PubMed Central.

Non-invasive early detection of acute transplant rejection via nanosensors of granzyme B activity.
Mac QD, Mathews DV, Kahla JA, Stoffers CM, Delmas OM, Holt BA, Adams AB, Kwong GA., Nat Biomed Eng 3(4), 2019
PMID: 30952979
Cysteine-type cathepsins promote the effector phase of acute cutaneous delayed-type hypersensitivity reactions.
Schwenck J, Maurer A, Fehrenbacher B, Mehling R, Knopf P, Mucha N, Haupt D, Fuchs K, Griessinger CM, Bukala D, Holstein J, Schaller M, Menendez IG, Ghoreschi K, Quintanilla-Martinez L, Gütschow M, Laufer S, Reinheckel T, Röcken M, Kalbacher H, Pichler BJ, Kneilling M., Theranostics 9(13), 2019
PMID: 31281521
Cathepsin D regulates cathepsin B activation and disease severity predominantly in inflammatory cells during experimental pancreatitis.
Aghdassi AA, John DS, Sendler M, Weiss FU, Reinheckel T, Mayerle J, Lerch MM., J Biol Chem 293(3), 2018
PMID: 29229780
In vivo inhibition of tryptophan catabolism reorganizes the tuberculoma and augments immune-mediated control of Mycobacterium tuberculosis.
Gautam US, Foreman TW, Bucsan AN, Veatch AV, Alvarez X, Adekambi T, Golden NA, Gentry KM, Doyle-Meyers LA, Russell-Lodrigue KE, Didier PJ, Blanchard JL, Kousoulas KG, Lackner AA, Kalman D, Rengarajan J, Khader SA, Kaushal D, Mehra S., Proc Natl Acad Sci U S A 115(1), 2018
PMID: 29255022
Unexpected cross-reactivity of anti-cathepsin B antibodies leads to uncertainties regarding the mechanism of action of anti-CD20 monoclonal antibody GA101.
Chien WW, Niogret C, Jugé R, Lionnard L, Cornut-Thibaut A, Kucharczak J, Savina A, Salles G, Aouacheria A., Leuk Res 55(), 2017
PMID: 28122282
Induction of cathepsin B by the CXCR3 chemokines CXCL9 and CXCL10 in human breast cancer cells.
Bronger H, Karge A, Dreyer T, Zech D, Kraeft S, Avril S, Kiechle M, Schmitt M., Oncol Lett 13(6), 2017
PMID: 28599423
Fluid shear-induced cathepsin B release in the control of Mac1-dependent neutrophil adhesion.
Akenhead ML, Fukuda S, Schmid-Schönbein GW, Shin HY., J Leukoc Biol 102(1), 2017
PMID: 28389621
Proteomic and functional analysis identifies galectin-1 as a novel regulatory component of the cytotoxic granule machinery.
Clemente T, Vieira NJ, Cerliani JP, Adrain C, Luthi A, Dominguez MR, Yon M, Barrence FC, Riul TB, Cummings RD, Zorn TM, Amigorena S, Dias-Baruffi M, Rodrigues MM, Martin SJ, Rabinovich GA, Amarante-Mendes GP., Cell Death Dis 8(12), 2017
PMID: 29215607
Melanoma cell lysosome secretory burst neutralizes the CTL-mediated cytotoxicity at the lytic synapse.
Khazen R, Müller S, Gaudenzio N, Espinosa E, Puissegur MP, Valitutti S., Nat Commun 7(), 2016
PMID: 26940455
Cathepsin B Activity Initiates Apoptosis via Digestive Protease Activation in Pancreatic Acinar Cells and Experimental Pancreatitis.
Sendler M, Maertin S, John D, Persike M, Weiss FU, Krüger B, Wartmann T, Wagh P, Halangk W, Schaschke N, Mayerle J, Lerch MM., J Biol Chem 291(28), 2016
PMID: 27226576
Cathepsin B-Deficient Mice Resolve Leishmania major Inflammation Faster in a T Cell-Dependent Manner.
Rasid O, Mériaux V, Khan EM, Borde C, Ciulean IS, Fitting C, Manoury B, Cavaillon JM, Doyen N., PLoS Negl Trop Dis 10(5), 2016
PMID: 27182703
Antithymocyte globulin facilitates alloreactive T-cell apoptosis by means of caspase-3: potential implications for monitoring rejection-free outcomes.
Ashokkumar C, Sun Q, Ningappa M, Higgs BW, Mazariegos G, Zeevi A, Sindhi R., Transplantation 99(1), 2015
PMID: 25531894
CD68 expression is a discriminative feature of indolent cutaneous CD8-positive lymphoid proliferation and distinguishes this lymphoma subtype from other CD8-positive cutaneous lymphomas.
Wobser M, Roth S, Reinartz T, Rosenwald A, Goebeler M, Geissinger E., Br J Dermatol 172(6), 2015
PMID: 25524664
Perforin and granzymes: function, dysfunction and human pathology.
Voskoboinik I, Whisstock JC, Trapani JA., Nat Rev Immunol 15(6), 2015
PMID: 25998963
A T-cell-directed chimeric antigen receptor for the selective treatment of T-cell malignancies.
Mamonkin M, Rouce RH, Tashiro H, Brenner MK., Blood 126(8), 2015
PMID: 26056165
Cysteine cathepsin proteases: regulators of cancer progression and therapeutic response.
Olson OC, Joyce JA., Nat Rev Cancer 15(12), 2015
PMID: 26597527
Nanopreparations for organelle-specific delivery in cancer.
Biswas S, Torchilin VP., Adv Drug Deliv Rev 66(), 2014
PMID: 24270008
The newly found functions of MTOC in immunological response.
Kloc M, Kubiak JZ, Li XC, Ghobrial RM., J Leukoc Biol 95(3), 2014
PMID: 24295827
Could bystander killing contribute significantly to the antitumor activity of brentuximab vedotin given with standard first-line chemotherapy for Hodgkin lymphoma?
Brown MP, Staudacher AH., Immunotherapy 6(4), 2014
PMID: 24815777
Cell biological steps and checkpoints in accessing NK cell cytotoxicity.
Mace EM, Dongre P, Hsu HT, Sinha P, James AM, Mann SS, Forbes LR, Watkin LB, Orange JS., Immunol Cell Biol 92(3), 2014
PMID: 24445602
Human immunodeficiency syndromes affecting human natural killer cell cytolytic activity.
Ham H, Billadeau DD., Front Immunol 5(), 2014
PMID: 24478771
Cysteine cathepsins as regulators of the cytotoxicity of NK and T cells.
Perišić Nanut M, Sabotič J, Jewett A, Kos J., Front Immunol 5(), 2014
PMID: 25520721
Open questions: missing pieces from the immunological jigsaw puzzle.
Griffiths GM., BMC Biol 11(), 2013
PMID: 23369631
Comparative glycomics of leukocyte glycosaminoglycans.
Shao C, Shi X, White M, Huang Y, Hartshorn K, Zaia J., FEBS J 280(10), 2013
PMID: 23480678
Fratricide of natural killer cells dressed with tumor-derived NKG2D ligand.
Nakamura K, Nakayama M, Kawano M, Amagai R, Ishii T, Harigae H, Ogasawara K., Proc Natl Acad Sci U S A 110(23), 2013
PMID: 23690625
Surface CD107a/LAMP-1 protects natural killer cells from degranulation-associated damage.
Cohnen A, Chiang SC, Stojanovic A, Schmidt H, Claus M, Saftig P, Janßen O, Cerwenka A, Bryceson YT, Watzl C., Blood 122(8), 2013
PMID: 23847195
In the crosshairs: investigating lytic granules by high-resolution microscopy and electrophysiology.
Pattu V, Halimani M, Ming M, Schirra C, Hahn U, Bzeih H, Chang HF, Weins L, Krause E, Rettig J., Front Immunol 4(), 2013
PMID: 24348478
Perforin is recaptured by natural killer cells following target cells stimulation for cytotoxicity.
Wang L, Sun R, Li P, Han Y, Xiong P, Xu Y, Fang M, Tan Z, Zheng F, Gong F., Cell Biol Int 36(2), 2012
PMID: 21981014
Ectopically expressed perforin-1 is proapoptotic in tumor cell lines by increasing caspase-3 activity and the nuclear translocation of cytochrome C.
Wang LF, Wang F, Li JT, Wen WH, Zhao J, Jia LT, Meng YL, Cao YX, Yao LB, Chen SY, Xu YM, Yang AG., PLoS One 7(7), 2012
PMID: 22829880
Cathepsin B: Basis Sequence: Mouse.
Cavallo-Medved D, Moin K, Sloane B., AFCS Nat Mol Pages 2011(), 2011
PMID: 28781583
Molecular mechanisms of induction of antigen-specific allograft tolerance by intranasal peptide administration.
Derbyshire K, Addey C, Coe D, Stuckey DW, Muezzin H, Bubier JA, Shaffer DJ, Roopenian DC, Chai JG, Scott DM., J Immunol 186(10), 2011
PMID: 21490154
Perforin: more than just a pore-forming protein.
Zhou F., Int Rev Immunol 29(1), 2010
PMID: 20100082
Pluripotent stem cells are highly susceptible targets for syngeneic, allogeneic, and xenogeneic natural killer cells.
Dressel R, Nolte J, Elsner L, Novota P, Guan K, Streckfuss-Bömeke K, Hasenfuss G, Jaenisch R, Engel W., FASEB J 24(7), 2010
PMID: 20145206
Tumour escape mechanisms and their therapeutic implications in combination tumour therapy.
Bhutia SK, Mallick SK, Maiti TK., Cell Biol Int 34(5), 2010
PMID: 20384587
Adaptive control of innate immunity.
Shanker A., Immunol Lett 131(2), 2010
PMID: 20394777
Granzyme A activates another way to die.
Lieberman J., Immunol Rev 235(1), 2010
PMID: 20536557
Serine protease inhibitors and cytotoxic T lymphocytes.
Ashton-Rickardt PG., Immunol Rev 235(1), 2010
PMID: 20536561
Granzyme B is recovered by natural killer cells via clathrin-dependent endocytosis.
Li P, Zheng G, Yang Y, Zhang C, Xiong P, Xu Y, Fang M, Tan Z, Zheng F, Gong F., Cell Mol Life Sci 67(18), 2010
PMID: 20449762
Antigen-specific cytotoxicity by invariant NKT cells in vivo is CD95/CD178-dependent and is correlated with antigenic potency.
Wingender G, Krebs P, Beutler B, Kronenberg M., J Immunol 185(5), 2010
PMID: 20660713
Proteases in lymphocyte killer function: redundancy, polymorphism and questions remaining.
Sutton VR, Trapani JA., Biol Chem 391(8), 2010
PMID: 20731542
Human and mouse perforin are processed in part through cleavage by the lysosomal cysteine proteinase cathepsin L.
Konjar S, Sutton VR, Hoves S, Repnik U, Yagita H, Reinheckel T, Peters C, Turk V, Turk B, Trapani JA, Kopitar-Jerala N., Immunology 131(2), 2010
PMID: 20497254
Visualizing CTL/melanoma cell interactions: multiple hits must be delivered for tumour cell annihilation.
Caramalho I, Faroudi M, Padovan E, Müller S, Valitutti S., J Cell Mol Med 13(9b), 2009
PMID: 19017355
Regulation of perforin lysis: implications for protein disulfide isomerase proteins.
Tamang DL, Alves BN, Elliott V, Redelman D, Wadhwa R, Fraser SA, Hudig D., Cell Immunol 255(1-2), 2009
PMID: 19147124
HBZ is an immunogenic protein, but not a target antigen for human T-cell leukemia virus type 1-specific cytotoxic T lymphocytes.
Suemori K, Fujiwara H, Ochi T, Ogawa T, Matsuoka M, Matsumoto T, Mesnard JM, Yasukawa M., J Gen Virol 90(pt 8), 2009
PMID: 19423550
Expression of the ULBP ligands for NKG2D by B-NHL cells plays an important role in determining their susceptibility to rituximab-induced ADCC.
Inagaki A, Ishida T, Yano H, Ishii T, Kusumoto S, Ito A, Ri M, Mori F, Ding J, Komatsu H, Iida S, Ueda R., Int J Cancer 125(1), 2009
PMID: 19358282
Multipotent adult germ-line stem cells, like other pluripotent stem cells, can be killed by cytotoxic T lymphocytes despite low expression of major histocompatibility complex class I molecules.
Dressel R, Guan K, Nolte J, Elsner L, Monecke S, Nayernia K, Hasenfuss G, Engel W., Biol Direct 4(), 2009
PMID: 19715575
Calcium influx and signaling in cytotoxic T-lymphocyte lytic granule exocytosis.
Pores-Fernando AT, Zweifach A., Immunol Rev 231(1), 2009
PMID: 19754896
Intracellular versus extracellular granzyme B in immunity and disease: challenging the dogma.
Boivin WA, Cooper DM, Hiebert PR, Granville DJ., Lab Invest 89(11), 2009
PMID: 19770840
The multiple sclerosis degradome: enzymatic cascades in development and progression of central nervous system inflammatory disease.
Scarisbrick IA., Curr Top Microbiol Immunol 318(), 2008
PMID: 18219817
Death by a thousand cuts: granzyme pathways of programmed cell death.
Chowdhury D, Lieberman J., Annu Rev Immunol 26(), 2008
PMID: 18304003
Leukocyte cell surface proteinases: regulation of expression, functions, and mechanisms of surface localization.
Owen CA., Int J Biochem Cell Biol 40(6-7), 2008
PMID: 18329945
Fluid shear-induced activation and cleavage of CD18 during pseudopod retraction by human neutrophils.
Shin HY, Simon SI, Schmid-Schönbein GW., J Cell Physiol 214(2), 2008
PMID: 17676580
Cysteine cathepsin S as an immunomodulatory target: present and future trends.
Gupta S, Singh RK, Dastidar S, Ray A., Expert Opin Ther Targets 12(3), 2008
PMID: 18269339
Inhibition of cathepsin L by epoxysuccinyl peptides simultaneously addressing active-site and remote-site regions.
Schaschke N, Assfalg-Machleidt I, Machleidt W., Chembiochem 9(11), 2008
PMID: 18551692
Origin and pathogenesis of nodular lymphocyte-predominant Hodgkin lymphoma as revealed by global gene expression analysis.
Brune V, Tiacci E, Pfeil I, Döring C, Eckerle S, van Noesel CJ, Klapper W, Falini B, von Heydebreck A, Metzler D, Bräuninger A, Hansmann ML, Küppers R., J Exp Med 205(10), 2008
PMID: 18794340
NK cells and Treg cells: a fascinating dance cheek to cheek.
Zimmer J, Andrès E, Hentges F., Eur J Immunol 38(11), 2008
PMID: 18979513
Granulysin is a key mediator for disseminated keratinocyte death in Stevens-Johnson syndrome and toxic epidermal necrolysis.
Chung WH, Hung SI, Yang JY, Su SC, Huang SP, Wei CY, Chin SW, Chiou CC, Chu SC, Ho HC, Yang CH, Lu CF, Wu JY, Liao YD, Chen YT., Nat Med 14(12), 2008
PMID: 19029983
Secretory lysosomes and their cargo in T and NK cells.
Lettau M, Schmidt H, Kabelitz D, Janssen O., Immunol Lett 108(1), 2007
PMID: 17097742
Secretory mechanisms in cell-mediated cytotoxicity.
Stinchcombe JC, Griffiths GM., Annu Rev Cell Dev Biol 23(), 2007
PMID: 17506701
(2S,3S)-Oxirane-2,3-dicarboxylic acid: a privileged platform for probing human cysteine cathepsins.
Schaschke N., J Biotechnol 129(2), 2007
PMID: 17339064
The effect of dexamethasone on polyclonal T cell activation and redirected target cell lysis as induced by a CD19/CD3-bispecific single-chain antibody construct.
Brandl C, Haas C, d'Argouges S, Fisch T, Kufer P, Brischwein K, Prang N, Bargou R, Suzich J, Baeuerle PA, Hofmeister R., Cancer Immunol Immunother 56(10), 2007
PMID: 17310380
Survival of priceless cells: active and passive protection of embryonic stem cells against immune destruction.
Utermöhlen O, Krönke M., Arch Biochem Biophys 462(2), 2007
PMID: 17459325
Cathepsin B is essential for regeneration of scratch-wounded normal human epidermal keratinocytes.
Büth H, Luigi Buttigieg P, Ostafe R, Rehders M, Dannenmann SR, Schaschke N, Stark HJ, Boukamp P, Brix K., Eur J Cell Biol 86(11-12), 2007
PMID: 17651862
Perforin enhances the granulysin-induced lysis of Listeria innocua in human dendritic cells.
Walch M, Latinovic-Golic S, Velic A, Sundstrom H, Dumrese C, Wagner CA, Groscurth P, Ziegler U., BMC Immunol 8(), 2007
PMID: 17705829
Protection of hepatocytes from cytotoxic T cell mediated killing by interferon-alpha.
Willberg CB, Ward SM, Clayton RF, Naoumov NV, McCormick C, Proto S, Harris M, Patel AH, Klenerman P., PLoS One 2(8), 2007
PMID: 17726521
Cleavage of cystatin C in the cerebrospinal fluid of patients with multiple sclerosis.
Irani DN, Anderson C, Gundry R, Cotter R, Moore S, Kerr DA, McArthur JC, Sacktor N, Pardo CA, Jones M, Calabresi PA, Nath A., Ann Neurol 59(2), 2006
PMID: 16437581
Distinct roles for cysteine cathepsin genes in multistage tumorigenesis.
Gocheva V, Zeng W, Ke D, Klimstra D, Reinheckel T, Peters C, Hanahan D, Joyce JA., Genes Dev 20(5), 2006
PMID: 16481467
LiveCount Assay: concomitant measurement of cytolytic activity and phenotypic characterisation of CD8(+) T-cells by flow cytometry.
Devêvre E, Romero P, Mahnke YD., J Immunol Methods 311(1-2), 2006
PMID: 16527300
Towards novel anti-cancer strategies based on cystatin function.
Keppler D., Cancer Lett 235(2), 2006
PMID: 15893421
Serine protease inhibitor 6 protects cytotoxic T cells from self-inflicted injury by ensuring the integrity of cytotoxic granules.
Zhang M, Park SM, Wang Y, Shah R, Liu N, Murmann AE, Wang CR, Peter ME, Ashton-Rickardt PG., Immunity 24(4), 2006
PMID: 16618603
The proinflammatory cytokine interleukin-18 alters multiple signaling pathways to inhibit natural killer cell death.
Hodge DL, Subleski JJ, Reynolds DA, Buschman MD, Schill WB, Burkett MW, Malyguine AM, Young HA., J Interferon Cytokine Res 26(10), 2006
PMID: 17032165
Perforin-mediated target-cell death and immune homeostasis.
Voskoboinik I, Smyth MJ, Trapani JA., Nat Rev Immunol 6(12), 2006
PMID: 17124515
Cysteine cathepsins: regulators of antitumour immune response.
Obermajer N, Doljak B, Kos J., Expert Opin Biol Ther 6(12), 2006
PMID: 17223738
Cost efficient and effective gene transfer into the human natural killer cell line, NK92.
Grund EM, Muise-Helmericks RC., J Immunol Methods 296(1-2), 2005
PMID: 15680148
Perforin and lymphohistiocytic proliferative disorders.
Katano H, Cohen JI., Br J Haematol 128(6), 2005
PMID: 15755277
Detection of functional cell surface perforin by flow cytometry.
Metkar SS, Wang B, Froelich CJ., J Immunol Methods 299(1-2), 2005
PMID: 15914196
Distinct role of lymphocyte function-associated antigen-1 in mediating effective cytolytic activity by cytotoxic T lymphocytes.
Anikeeva N, Somersalo K, Sims TN, Thomas VK, Dustin ML, Sykulev Y., Proc Natl Acad Sci U S A 102(18), 2005
PMID: 15851656
Cathepsin B regulates the intrinsic angiogenic threshold of endothelial cells.
Im E, Venkatakrishnan A, Kazlauskas A., Mol Biol Cell 16(8), 2005
PMID: 15901832
Perforin triggers a plasma membrane-repair response that facilitates CTL induction of apoptosis.
Keefe D, Shi L, Feske S, Massol R, Navarro F, Kirchhausen T, Lieberman J., Immunity 23(3), 2005
PMID: 16169498
BiTEs: bispecific antibody constructs with unique anti-tumor activity.
Wolf E, Hofmeister R, Kufer P, Schlereth B, Baeuerle PA., Drug Discov Today 10(18), 2005
PMID: 16213416
Molecular cloning and characterization of Cathepsin B from a scuticociliate, Uronema marinum.
Lim SU, Seo JS, Kim MS, Ahn SJ, Jeong HD, Kim KH, Park NG, Kim JK, Chung JK, Lee HH., Comp Biochem Physiol B Biochem Mol Biol 142(3), 2005
PMID: 16172011
A cathepsin L isoform that is devoid of a signal peptide localizes to the nucleus in S phase and processes the CDP/Cux transcription factor.
Goulet B, Baruch A, Moon NS, Poirier M, Sansregret LL, Erickson A, Bogyo M, Nepveu A., Mol Cell 14(2), 2004
PMID: 15099520
Characterization of murine cathepsin W and its role in cell-mediated cytotoxicity.
Ondr JK, Pham CT., J Biol Chem 279(26), 2004
PMID: 15087452
Cathepsin cysteine proteases are effectors of invasive growth and angiogenesis during multistage tumorigenesis.
Joyce JA, Baruch A, Chehade K, Meyer-Morse N, Giraudo E, Tsai FY, Greenbaum DC, Hager JH, Bogyo M, Hanahan D., Cancer Cell 5(5), 2004
PMID: 15144952
A novel flow cytometric assay focusing on perforin release mechanisms of cytotoxic T lymphocytes.
Weren A, Bonnekoh B, Schraven B, Gollnick H, Ambach A., J Immunol Methods 289(1-2), 2004
PMID: 15251408
Cytotoxic activity of the lymphocyte toxin granzyme B.
Wowk ME, Trapani JA., Microbes Infect 6(8), 2004
PMID: 15207822
Crystal structure of NS-134 in complex with bovine cathepsin B: a two-headed epoxysuccinyl inhibitor extends along the entire active-site cleft.
Stern I, Schaschke N, Moroder L, Turk D., Biochem J 381(pt 2), 2004
PMID: 15084146
Serine protease inhibitor 2A is a protective factor for memory T cell development.
Liu N, Phillips T, Zhang M, Wang Y, Opferman JT, Shah R, Ashton-Rickardt PG., Nat Immunol 5(9), 2004
PMID: 15311278
The ABCs of granule-mediated cytotoxicity: new weapons in the arsenal.
Lieberman J., Nat Rev Immunol 3(5), 2003
PMID: 12766758
Delivering the kiss of death.
Trambas CM, Griffiths GM., Nat Immunol 4(5), 2003
PMID: 12719728
Defective cytotoxic granule-mediated cell death pathway impairs T lymphocyte homeostasis.
de Saint Basile G, Fischer A., Curr Opin Rheumatol 15(4), 2003
PMID: 12819472
Measuring T cell-mediated cytotoxicity using fluorogenic caspase substrates.
Chahroudi A, Silvestri G, Feinberg MB., Methods 31(2), 2003
PMID: 12957569
Perforin and the granule exocytosis cytotoxicity pathway.
Catalfamo M, Henkart PA., Curr Opin Immunol 15(5), 2003
PMID: 14499260
N-arylaminonitriles as bioavailable peptidomimetic inhibitors of cathepsin B.
Greenspan PD, Clark KL, Cowen SD, McQuire LW, Tommasi RA, Farley DL, Quadros E, Coppa DE, Du Z, Fang Z, Zhou H, Doughty J, Toscano KT, Wigg AM, Zhou S., Bioorg Med Chem Lett 13(22), 2003
PMID: 14592520
The defect of the perforin granule system in cytotoxic T lymphocytes of atopic patients--are perforin reduction and hyperreleasability of clinical relevance?
Ambach A, Bonnekoh B, Gollnick H., J Dtsch Dermatol Ges 1(12), 2003
PMID: 16285645
Functional significance of the perforin/granzyme cell death pathway.
Trapani JA, Smyth MJ., Nat Rev Immunol 2(10), 2002
PMID: 12360212
The secretory synapse: the secrets of a serial killer.
Bossi G, Trambas C, Booth S, Clark R, Stinchcombe J, Griffiths GM., Immunol Rev 189(), 2002
PMID: 12445272

59 References

Daten bereitgestellt von Europe PubMed Central.

Lymphocyte-mediated cytotoxicity: two pathways and multiple effector molecules.
Henkart PA., Immunity 1(5), 1994
PMID: 7882166
CD8+ T cell effector mechanisms in resistance to infection.
Harty JT, Tvinnereim AR, White DW., Annu. Rev. Immunol. 18(), 2000
PMID: 10837060
Perforin-mediated cytotoxicity is critical for surveillance of spontaneous lymphoma.
Smyth MJ, Thia KY, Street SE, MacGregor D, Godfrey DI, Trapani JA., J. Exp. Med. 192(5), 2000
PMID: 10974040
Perforin gene defects in familial hemophagocytic lymphohistiocytosis.
Stepp SE, Dufourcq-Lagelouse R, Le Deist F, Bhawan S, Certain S, Mathew PA, Henter JI, Bennett M, Fischer A, de Saint Basile G, Kumar V., Science 286(5446), 1999
PMID: 10583959
An inherited disorder of lymphocyte apoptosis: the autoimmune lymphoproliferative syndrome.
Straus SE, Sneller M, Lenardo MJ, Puck JM, Strober W., Ann. Intern. Med. 130(7), 1999
PMID: 10189330
Target cell lysis by CTL granule exocytosis is independent of ICE/Ced-3 family proteases.
Sarin A, Williams MS, Alexander-Miller MA, Berzofsky JA, Zacharchuk CM, Henkart PA., Immunity 6(2), 1997
PMID: 9047242
Cytotoxic T lymphocyte sequential killing of immobilized allogeneic tumor target cells measured by time-lapse microcinematography.
Rothstein TL, Mage M, Jones G, McHugh LL., J. Immunol. 121(5), 1978
PMID: 309477

AUTHOR UNKNOWN, 0
Self-sparing of long-term in vitro-cloned or uncloned cytotoxic T lymphocytes.
Luciani MF, Brunet JF, Suzan M, Denizot F, Golstein P., J. Exp. Med. 164(3), 1986
PMID: 3489065
Resistance of cytotoxic T lymphocytes to lysis by a clone of cytotoxic T lymphocytes.
Kranz DM, Eisen HN., Proc. Natl. Acad. Sci. U.S.A. 84(10), 1987
PMID: 2953028
Resistance of cloned cytotoxic T lymphocytes to cell-mediated cytotoxicity.
Blakely A, Gorman K, Ostergaard H, Svoboda K, Liu CC, Young JD, Clark WR., J. Exp. Med. 166(4), 1987
PMID: 3498787
Resistance of cytotoxic T lymphocytes to the lytic effects of their toxic granules.
Verret CR, Firmenich AA, Kranz DM, Eisen HN., J. Exp. Med. 166(5), 1987
PMID: 2445890
Resistance of cytolytic lymphocytes to perforin-mediated killing. Induction of resistance correlates with increase in cytotoxicity.
Liu CC, Jiang S, Persechini PM, Zychlinsky A, Kaufmann Y, Young JD., J. Exp. Med. 169(6), 1989
PMID: 2786549
Resistance of CTL to perforin-mediated lysis. Evidence for a lymphocyte membrane protein interacting with perforin.
Muller C, Tschopp J., J. Immunol. 153(6), 1994
PMID: 7521362
Resistance of cytolytic lymphocytes to perforin-mediated killing. Inhibition of perforin binding activity by surface membrane proteins.
Jiang SB, Ojcius DM, Persechini PM, Young JD., J. Immunol. 144(3), 1990
PMID: 2104915
The lysis of cytotoxic T lymphocytes and their blasts by cytotoxic T lymphocytes.
Schick B, Berke G., Immunology 71(3), 1990
PMID: 2269479
Cognate peptides induce self-destruction of CD8+ cytolytic T lymphocytes.
Walden PR, Eisen HN., Proc. Natl. Acad. Sci. U.S.A. 87(22), 1990
PMID: 2123347
Cognate peptide-induced destruction of CD8+ cytotoxic T lymphocytes is due to fratricide.
Su MW, Walden PR, Golan DB, Eisen HN., J. Immunol. 151(2), 1993
PMID: 8335901
Effects of cognate peptides on cytolytic and proliferative activities of cloned cytotoxic T lymphocytes.
Dutz JP, Walden PR, Eisen HN., Int. Immunol. 4(5), 1992
PMID: 1378297
Fratricide among CD8(+) T lymphocytes naturally infected with human T cell lymphotropic virus type I.
Hanon E, Stinchcombe JC, Saito M, Asquith BE, Taylor GP, Tanaka Y, Weber JN, Griffiths GM, Bangham CR., Immunity 13(5), 2000
PMID: 11114378
L is for lytic granules: lysosomes that kill.
Page LJ, Darmon AJ, Uellner R, Griffiths GM., Biochim. Biophys. Acta 1401(2), 1998
PMID: 9531970
Human procathepsin B interacts with the annexin II tetramer on the surface of tumor cells.
Mai J, Finley RL Jr, Waisman DM, Sloane BF., J. Biol. Chem. 275(17), 2000
PMID: 10777578
Fluorescent microplate assay for cancer cell-associated cathepsin B.
Hulkower KI, Butler CC, Linebaugh BE, Klaus JL, Keppler D, Giranda VL, Sloane BF., Eur. J. Biochem. 267(13), 2000
PMID: 10866820
Dissociation of membrane binding and lytic activities of the lymphocyte pore-forming protein (perforin).
Young JD, Damiano A, DiNome MA, Leong LG, Cohn ZA., J. Exp. Med. 165(5), 1987
PMID: 3494808
Mechanism of lysis by large granular lymphocyte granule cytolysin: generation of a stable cytolysin-RBC intermediate.
Kuta AE, Reynolds CR, Henkart PA., J. Immunol. 142(12), 1989
PMID: 2723433
Characterization of non-lytic cytolysin-membrane intermediates.
Kuta AE, Bashford CL, Pasternak CA, Reynolds CW, Henkart PA., Mol. Immunol. 28(11), 1991
PMID: 1961199
Preferential proliferation of natural killer cells among peripheral blood mononuclear cells cocultured with B lymphoblastoid cell lines.
Perussia B, Ramoni C, Anegon I, Cuturi MC, Faust J, Trinchieri G., Nat. Immun. Cell Growth Regul. 6(4), 1987
PMID: 2960890
Synthesis of peptide fluoromethyl ketones and the inhibition of human cathepsin B.
Rasnick D., Anal. Biochem. 149(2), 1985
PMID: 4073501
The design of peptidyldiazomethane inhibitors to distinguish between the cysteine proteinases calpain II, cathepsin L and cathepsin B.
Crawford C, Mason RW, Wikstrom P, Shaw E., Biochem. J. 253(3), 1988
PMID: 2845932
Concanamycin A, a powerful tool for characterization and estimation of contribution of perforin- and Fas-based lytic pathways in cell-mediated cytotoxicity.
Kataoka T, Shinohara N, Takayama H, Takaku K, Kondo S, Yonehara S, Nagai K., J. Immunol. 156(10), 1996
PMID: 8621902
Similar molecular requirements for antigen receptor-triggered secretion of interferon and granule enzymes by cytolytic T lymphocytes.
Fortier AH, Nacy CA, Sitkovsky MV., Cell. Immunol. 124(1), 1989
PMID: 2478302
Defective granule exocytosis in Rab27a-deficient lymphocytes from Ashen mice.
Haddad EK, Wu X, Hammer JA 3rd, Henkart PA., J. Cell Biol. 152(4), 2001
PMID: 11266473
Inducible nonlymphoid expression of Fas ligand is responsible for superantigen-induced peripheral deletion of T cells.
Bonfoco E, Stuart PM, Brunner T, Lin T, Griffith TS, Gao Y, Nakajima H, Henkart PA, Ferguson TA, Green DR., Immunity 9(5), 1998
PMID: 9846492
CD16 cross-linking induces both secretory and extracellular signal-regulated kinase (ERK)-dependent cytosolic phospholipase A2 (PLA2) activity in human natural killer cells: involvement of ERK, but not PLA2, in CD16-triggered granule exocytosis.
Milella M, Gismondi A, Roncaioli P, Bisogno L, Palmieri G, Frati L, Cifone MG, Santoni A., J. Immunol. 158(7), 1997
PMID: 9120268
Structural basis of inhibition of cysteine proteases by E-64 and its derivatives.
Matsumoto K, Mizoue K, Kitamura K, Tse WC, Huber CP, Ishida T., Biopolymers 51(1), 1999
PMID: 10380357
CA074 methyl ester: a proinhibitor for intracellular cathepsin B.
Buttle DJ, Murata M, Knight CG, Barrett AJ., Arch. Biochem. Biophys. 299(2), 1992
PMID: 1444478
Epoxysuccinyl peptide-derived affinity labels for cathepsin B.
Schaschke N, Assfalg-Machleidt I, Lassleben T, Sommerhoff CP, Moroder L, Machleidt W., FEBS Lett. 482(1-2), 2000
PMID: 11018529
Caspase dependence of target cell damage induced by cytotoxic lymphocytes.
Sarin A, Haddad EK, Henkart PA., J. Immunol. 161(6), 1998
PMID: 9743340
Cysteinyl proteinases and their selective inactivation.
Shaw E., Adv. Enzymol. Relat. Areas Mol. Biol. 63(), 1990
PMID: 2407065

AUTHOR UNKNOWN, 0
The lysosomal cysteine proteases.
McGrath ME., Annu Rev Biophys Biomol Struct 28(), 1999
PMID: 10410800
Lysosomal cysteine proteases: facts and opportunities.
Turk V, Turk B, Turk D., EMBO J. 20(17), 2001
PMID: 11532926
Human cathepsin W, a putative cysteine protease predominantly expressed in CD8+ T-lymphocytes.
Linnevers C, Smeekens SP, Bromme D., FEBS Lett. 405(3), 1997
PMID: 9108299
Lymphopain, a cytotoxic T and natural killer cell-associated cysteine proteinase.
Brown J, Matutes E, Singleton A, Price C, Molgaard H, Buttle D, Enver T., Leukemia 12(11), 1998
PMID: 9823953
Human cathepsins F and W: A new subgroup of cathepsins.
Wex T, Levy B, Wex H, Bromme D., Biochem. Biophys. Res. Commun. 259(2), 1999
PMID: 10362521
Human cathepsin W, a cysteine protease predominantly expressed in NK cells, is mainly localized in the endoplasmic reticulum.
Wex T, Buhling F, Wex H, Gunther D, Malfertheiner P, Weber E, Bromme D., J. Immunol. 167(4), 2001
PMID: 11490002
Cysteine Proteases and Their Inhibitors.
Otto HH, Schirmeister T., Chem. Rev. 97(1), 1997
PMID: 11848867
Substrate/propeptide-derived endo-epoxysuccinyl peptides as highly potent and selective cathepsin B inhibitors.
Schaschke N, Assfalg-Machleidt I, Machleidt W, Moroder L., FEBS Lett. 421(1), 1998
PMID: 9462845
A cytosolic granzyme B inhibitor related to the viral apoptotic regulator cytokine response modifier A is present in cytotoxic lymphocytes.
Sun J, Bird CH, Sutton V, McDonald L, Coughlin PB, De Jong TA, Trapani JA, Bird PI., J. Biol. Chem. 271(44), 1996
PMID: 8910377
Selective regulation of apoptosis: the cytotoxic lymphocyte serpin proteinase inhibitor 9 protects against granzyme B-mediated apoptosis without perturbing the Fas cell death pathway.
Bird CH, Sutton VR, Sun J, Hirst CE, Novak A, Kumar S, Trapani JA, Bird PI., Mol. Cell. Biol. 18(11), 1998
PMID: 9774654
The granzyme B inhibitor, protease inhibitor 9, is mainly expressed by dendritic cells and at immune-privileged sites.
Bladergroen BA, Strik MC, Bovenschen N, van Berkum O, Scheffer GL, Meijer CJ, Hack CE, Kummer JA., J. Immunol. 166(5), 2001
PMID: 11207275
Natural killer and lymphokine-activated killer cells require granzyme B for the rapid induction of apoptosis in susceptible target cells.
Shresta S, MacIvor DM, Heusel JW, Russell JH, Ley TJ., Proc. Natl. Acad. Sci. U.S.A. 92(12), 1995
PMID: 7777569
Viral immune evasion strategies and the underlying cell biology.
Lorenzo ME, Ploegh HL, Tirabassi RS., Semin. Immunol. 13(1), 2001
PMID: 11289794
Impaired binding of perforin on the surface of tumor cells is a cause of target cell resistance against cytotoxic effector cells.
Lehmann C, Zeis M, Schmitz N, Uharek L., Blood 96(2), 2000
PMID: 10887123
Cell surface complex of cathepsin B/annexin II tetramer in malignant progression.
Mai J, Waisman DM, Sloane BF., Biochim. Biophys. Acta 1477(1-2), 2000
PMID: 10708859
A fresh look at tumor immunosurveillance and immunotherapy.
Smyth MJ, Godfrey DI, Trapani JA., Nat. Immunol. 2(4), 2001
PMID: 11276199
A role for perforin in activation-induced cell death.
Spaner D, Raju K, Radvanyi L, Lin Y, Miller RG., J. Immunol. 160(6), 1998
PMID: 9510164
A role for perforin in activation-induced T cell death in vivo: increased expansion of allogeneic perforin-deficient T cells in SCID mice.
Spaner D, Raju K, Rabinovich B, Miller RG., J. Immunol. 162(2), 1999
PMID: 9916752
A role for perforin in downregulating T-cell responses during chronic viral infection.
Matloubian M, Suresh M, Glass A, Galvan M, Chow K, Whitmire JK, Walsh CM, Clark WR, Ahmed R., J. Virol. 73(3), 1999
PMID: 9971838
Export

Markieren/ Markierung löschen
Markierte Publikationen

Open Data PUB

Web of Science

Dieser Datensatz im Web of Science®
Quellen

PMID: 12186841
PubMed | Europe PMC

Suchen in

Google Scholar