PUB - Publikationen an der Universität Bielefeld

Alle markieren

• [32]
  

  2023 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2981179

  N. Tromsdorf, et al., “E-64c-hydrazide based cathepsin C inhibitors: Optimizing the interactions with the S1'-S2' area”, ChemMedChem, 2023, : e202300218.

  PUB | PDF | DOI | WoS | PubMed | Europe PMC
   
• [31]
  

  2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2703442

  G. Mikhaylov, et al., “Selective Targeting of Tumor and Stromal Cells By a Nanocarrier System Displaying Lipidated Cathepsin B Inhibitor”, Angewandte Chemie International Edition, vol. 53, 2014, pp. 10077-10081.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [30]
  

  2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2699425

  T. Tamhane, et al., “The activity and localization patterns of cathepsins B and X in cells of the mouse gastrointestinal tract differ along its length”, Biological Chemistry, vol. 395, 2014, pp. 1201-1219.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [29]
  

  2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2622177

  H. Radzey, et al., “E-64c-Hydrazide: A Lead Structure for the Development of Irreversible CathepsinC Inhibitors”, Chemmedchem, vol. 8, 2013, pp. 1314-1321.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [28]
  

  2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2489346

  M. Kalinska, et al., “Substrate specificity of Staphylococcus aureus cysteine proteases - Staphopains A, B and C”, Biochimie, vol. 94, 2012, pp. 318-327.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [27]
  

  2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2489135

  S. Diederich, et al., “Activation of the Nipah Virus Fusion Protein in MDCK Cells Is Mediated by Cathepsin B within the Endosome-Recycling Compartment”, Journal of Virology, vol. 86, 2012, pp. 3736-3745.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [26]
  

  2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2454769

  D. Janke, C.P. Sommerhoff, and N. Schaschke, “The arginine mimicking beta-amino acid beta(3)hPhe(3-H(2)N-CH(2)) as S1 ligand in cyclotheonamide-based beta-tryptase inhibitors”, Bioorganic & Medicinal Chemistry, vol. 19, 2011, pp. 7236-7243.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [25]
  

  2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403684

  U. Schurigt, et al., “Aziridine-2,3-Dicarboxylate-Based Cysteine Cathepsin Inhibitors Induce Cell Death in Leishmania major Associated with Accumulation of Debris in Autophagy-Related Lysosome-Like Vacuoles”, ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, vol. 54, 2010, pp. 5028-5041.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [24]
  

  2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403708

  N. Schaschke and C.P. Sommerhoff, “Upgrading a Natural Product: Inhibition of Human beta-Tryptase by Cyclotheonamide Analogues”, CHEMMEDCHEM, vol. 5, 2010, pp. 367-370.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [23]
  

  2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403720

  J. Pfizer, et al., “Inhibition of human mu-calpain by conformationally constrained calpastatin peptides”, BIOLOGICAL CHEMISTRY, vol. 389, 2008, pp. 83-90.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [22]
  

  2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403715

  N. Schaschke, I. Assfalg-Machleidt, and W. Machleidt, “Inhibition of cathepsin L by epoxysuccinyl peptides simultaneously addressing active-site and remote-site regions”, CHEMBIOCHEM, vol. 9, 2008, pp. 1721-1724.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [21]
  

  2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403726

  H. Bueth, et al., “Cathepsin B is essential for regeneration of scratch-wounded normal human epidermal keratinocytes”, EUROPEAN JOURNAL OF CELL BIOLOGY, vol. 86, 2007, pp. 747-761.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [20]
  

  2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403747

  C.P. Sommerhoff and N. Schaschke, “Mast cell tryptase beta as a target in allergic inflammation: An evolving story”, CURRENT PHARMACEUTICAL DESIGN, vol. 13, 2007, pp. 313-332.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [19]
  

  2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403737

  J.M. Pfizer, et al., “Primed-site probing of papain-like cysteine proteases”, INTERNATIONAL JOURNAL OF PEPTIDE RESEARCH AND THERAPEUTICS, vol. 13, 2007, pp. 93-104.

  PUB | DOI | WoS
   
• [18]
  

  2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403744

  N. Schaschke, “(2S,3S)-Oxirane-2,3-dicarboxylic acid: A privileged platform for probing human cysteine cathepsins”, JOURNAL OF BIOTECHNOLOGY, vol. 129, 2007, pp. 308-315.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [17]
  

  2005 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403754

  N. Schaschke, et al., “Affinity chromatography of tryptases: Design, synthesis and characterization of a novel matrix-bound bivalent inhibitor”, CHEMBIOCHEM, vol. 6, 2005, pp. 95-103.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [16]
  

  2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403774

  I. Stern, et al., “Crystal structure of NS-134 in complex with bovine cathepsin B: a two-headed epoxysuccinyl inhibitor extends along the entire active-site cleft”, BIOCHEMICAL JOURNAL, vol. 381, 2004, pp. 511-517.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [15]
  

  2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403779

  C. Giragossian, et al., “Conformational and molecular modeling studies of beta-cyclodextrin-heptagastrin and the third extracellular loop of the cholecystokinin 2 receptor”, BIOCHEMISTRY, vol. 43, 2004, pp. 2724-2731.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [14]
  

  2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403785

  N. Schaschke, “Miraziridine A: natures blueprint towards protease class-spanning inhibitors”, BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 14, 2004, pp. 855-857.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [13]
  

  2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403760

  H. Buth, et al., “HaCaT keratinocytes secrete lysosomal cysteine proteinases during migration”, EUROPEAN JOURNAL OF CELL BIOLOGY, vol. 83, 2004, pp. 781-795.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [12]
  

  2003 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403798

  S. Gil-Parrado, et al., “Calpastatin exon 1B-derived peptide, a selective inhibitor of calpain: Enhancing cell permeability by conjugation with penetratin”, BIOLOGICAL CHEMISTRY, vol. 384, 2003, pp. 395-402.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [11]
  

  2002 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403813

  K.N. Balaji, et al., “Surface cathepsin B protects cytotoxic lymphocytes from self-destruction after degranulation”, JOURNAL OF EXPERIMENTAL MEDICINE, vol. 196, 2002, pp. 493-503.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [10]
  

  2002 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403820

  N. Schaschke, et al., “Epoxysuccinyl peptide-derived cathepsin B inhibitors: Modulating membrane permeability by conjugation with the C-terminal heptapeptide segment of penetratin”, BIOLOGICAL CHEMISTRY, vol. 383, 2002, pp. 849-852.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [9]
  

  2002 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403828

  N. Schaschke, et al., “Bivalent inhibition of beta-tryptase: Distance scan of neighboring subunits by dibasic inhibitors”, BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 12, 2002, pp. 985-988.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [8]
  

  2001 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403834

  N. Schaschke, et al., “Bivalent inhibition of human beta-tryptase”, CHEMISTRY & BIOLOGY, vol. 8, 2001, pp. 313-327.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [7]
  

  2000 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403844

  N. Schaschke, et al., “Epoxysuccinyl peptide-derived affinity labels for cathepsin B”, FEBS LETTERS, vol. 482, 2000, pp. 91-96.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [6]
  

  2000 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403852

  N. Schaschke, et al., “beta-cyclodextrin/epoxysuccinyl peptide conjugates: new drug targeting system for tumor cells”, BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 10, 2000, pp. 677-680.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [5]
  

  1998 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403860

  N. Schaschke, et al., “Cyclodextrin as carrier of peptide hormones. Conformational and biological properties of beta-cyclodextrin/gastrin constructs”, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 120, 1998, pp. 7030-7038.

  PUB | DOI | WoS
   
• [4]
  

  1998 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403869

  N. Schaschke, et al., “Substrate/propeptide-derived endo-epoxysuccinyl peptides as highly potent and selective cathepsin B inhibitors”, FEBS LETTERS, vol. 421, 1998, pp. 80-82.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [3]
  

  1997 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403875

  N. Schaschke, et al., “Oligopresentation of protease inhibitors with beta-cyclodextrin as template”, BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 7, 1997, pp. 2507-2512.

  PUB | DOI | WoS
   
• [2]
  

  1997 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403882

  N. Schaschke, et al., “E-64 analogues as inhibitors of cathepsin B. On the role of the absolute configuration of the epoxysuccinyl group”, BIOORGANIC & MEDICINAL CHEMISTRY, vol. 5, 1997, pp. 1789-1797.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [1]
  

  1996 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403889

  N. Schaschke, et al., “Cyclodextrins as templates for the presentation of protease inhibitors”, FEBS LETTERS, vol. 391, 1996, pp. 297-301.

  PUB | DOI | WoS | PubMed | Europe PMC