32 Publikationen
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2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2703442G. Mikhaylov, et al., “Selective Targeting of Tumor and Stromal Cells By a Nanocarrier System Displaying Lipidated Cathepsin B Inhibitor”, Angewandte Chemie International Edition, vol. 53, 2014, pp. 10077-10081.PUB | DOI | WoS | PubMed | Europe PMC
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2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2699425T. Tamhane, et al., “The activity and localization patterns of cathepsins B and X in cells of the mouse gastrointestinal tract differ along its length”, Biological Chemistry, vol. 395, 2014, pp. 1201-1219.PUB | DOI | WoS | PubMed | Europe PMC
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2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2622177H. Radzey, et al., “E-64c-Hydrazide: A Lead Structure for the Development of Irreversible CathepsinC Inhibitors”, Chemmedchem, vol. 8, 2013, pp. 1314-1321.PUB | DOI | WoS | PubMed | Europe PMC
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2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2489346M. Kalinska, et al., “Substrate specificity of Staphylococcus aureus cysteine proteases - Staphopains A, B and C”, Biochimie, vol. 94, 2012, pp. 318-327.PUB | DOI | WoS | PubMed | Europe PMC
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2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2489135S. Diederich, et al., “Activation of the Nipah Virus Fusion Protein in MDCK Cells Is Mediated by Cathepsin B within the Endosome-Recycling Compartment”, Journal of Virology, vol. 86, 2012, pp. 3736-3745.PUB | DOI | WoS | PubMed | Europe PMC
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2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2454769D. Janke, C.P. Sommerhoff, and N. Schaschke, “The arginine mimicking beta-amino acid beta(3)hPhe(3-H(2)N-CH(2)) as S1 ligand in cyclotheonamide-based beta-tryptase inhibitors”, Bioorganic & Medicinal Chemistry, vol. 19, 2011, pp. 7236-7243.PUB | DOI | WoS | PubMed | Europe PMC
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2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403684U. Schurigt, et al., “Aziridine-2,3-Dicarboxylate-Based Cysteine Cathepsin Inhibitors Induce Cell Death in Leishmania major Associated with Accumulation of Debris in Autophagy-Related Lysosome-Like Vacuoles”, ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, vol. 54, 2010, pp. 5028-5041.PUB | DOI | WoS | PubMed | Europe PMC
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2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403708N. Schaschke and C.P. Sommerhoff, “Upgrading a Natural Product: Inhibition of Human beta-Tryptase by Cyclotheonamide Analogues”, CHEMMEDCHEM, vol. 5, 2010, pp. 367-370.PUB | DOI | WoS | PubMed | Europe PMC
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2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403720J. Pfizer, et al., “Inhibition of human mu-calpain by conformationally constrained calpastatin peptides”, BIOLOGICAL CHEMISTRY, vol. 389, 2008, pp. 83-90.PUB | DOI | WoS | PubMed | Europe PMC
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2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403715N. Schaschke, I. Assfalg-Machleidt, and W. Machleidt, “Inhibition of cathepsin L by epoxysuccinyl peptides simultaneously addressing active-site and remote-site regions”, CHEMBIOCHEM, vol. 9, 2008, pp. 1721-1724.PUB | DOI | WoS | PubMed | Europe PMC
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2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403726H. Bueth, et al., “Cathepsin B is essential for regeneration of scratch-wounded normal human epidermal keratinocytes”, EUROPEAN JOURNAL OF CELL BIOLOGY, vol. 86, 2007, pp. 747-761.PUB | DOI | WoS | PubMed | Europe PMC
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2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403747C.P. Sommerhoff and N. Schaschke, “Mast cell tryptase beta as a target in allergic inflammation: An evolving story”, CURRENT PHARMACEUTICAL DESIGN, vol. 13, 2007, pp. 313-332.PUB | DOI | WoS | PubMed | Europe PMC
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2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403744N. Schaschke, “(2S,3S)-Oxirane-2,3-dicarboxylic acid: A privileged platform for probing human cysteine cathepsins”, JOURNAL OF BIOTECHNOLOGY, vol. 129, 2007, pp. 308-315.PUB | DOI | WoS | PubMed | Europe PMC
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2005 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403754N. Schaschke, et al., “Affinity chromatography of tryptases: Design, synthesis and characterization of a novel matrix-bound bivalent inhibitor”, CHEMBIOCHEM, vol. 6, 2005, pp. 95-103.PUB | DOI | WoS | PubMed | Europe PMC
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2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403774I. Stern, et al., “Crystal structure of NS-134 in complex with bovine cathepsin B: a two-headed epoxysuccinyl inhibitor extends along the entire active-site cleft”, BIOCHEMICAL JOURNAL, vol. 381, 2004, pp. 511-517.PUB | DOI | WoS | PubMed | Europe PMC
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2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403779C. Giragossian, et al., “Conformational and molecular modeling studies of beta-cyclodextrin-heptagastrin and the third extracellular loop of the cholecystokinin 2 receptor”, BIOCHEMISTRY, vol. 43, 2004, pp. 2724-2731.PUB | DOI | WoS | PubMed | Europe PMC
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2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403785N. Schaschke, “Miraziridine A: natures blueprint towards protease class-spanning inhibitors”, BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 14, 2004, pp. 855-857.PUB | DOI | WoS | PubMed | Europe PMC
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2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403760H. Buth, et al., “HaCaT keratinocytes secrete lysosomal cysteine proteinases during migration”, EUROPEAN JOURNAL OF CELL BIOLOGY, vol. 83, 2004, pp. 781-795.PUB | DOI | WoS | PubMed | Europe PMC
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2003 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403798S. Gil-Parrado, et al., “Calpastatin exon 1B-derived peptide, a selective inhibitor of calpain: Enhancing cell permeability by conjugation with penetratin”, BIOLOGICAL CHEMISTRY, vol. 384, 2003, pp. 395-402.PUB | DOI | WoS | PubMed | Europe PMC
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2002 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403813K.N. Balaji, et al., “Surface cathepsin B protects cytotoxic lymphocytes from self-destruction after degranulation”, JOURNAL OF EXPERIMENTAL MEDICINE, vol. 196, 2002, pp. 493-503.PUB | DOI | WoS | PubMed | Europe PMC
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2002 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403820N. Schaschke, et al., “Epoxysuccinyl peptide-derived cathepsin B inhibitors: Modulating membrane permeability by conjugation with the C-terminal heptapeptide segment of penetratin”, BIOLOGICAL CHEMISTRY, vol. 383, 2002, pp. 849-852.PUB | DOI | WoS | PubMed | Europe PMC
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2002 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403828N. Schaschke, et al., “Bivalent inhibition of beta-tryptase: Distance scan of neighboring subunits by dibasic inhibitors”, BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 12, 2002, pp. 985-988.PUB | DOI | WoS | PubMed | Europe PMC
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2001 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403834N. Schaschke, et al., “Bivalent inhibition of human beta-tryptase”, CHEMISTRY & BIOLOGY, vol. 8, 2001, pp. 313-327.PUB | DOI | WoS | PubMed | Europe PMC
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2000 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403844N. Schaschke, et al., “Epoxysuccinyl peptide-derived affinity labels for cathepsin B”, FEBS LETTERS, vol. 482, 2000, pp. 91-96.PUB | DOI | WoS | PubMed | Europe PMC
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2000 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403852N. Schaschke, et al., “beta-cyclodextrin/epoxysuccinyl peptide conjugates: new drug targeting system for tumor cells”, BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 10, 2000, pp. 677-680.PUB | DOI | WoS | PubMed | Europe PMC
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1998 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403860N. Schaschke, et al., “Cyclodextrin as carrier of peptide hormones. Conformational and biological properties of beta-cyclodextrin/gastrin constructs”, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 120, 1998, pp. 7030-7038.PUB | DOI | WoS
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1998 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403869N. Schaschke, et al., “Substrate/propeptide-derived endo-epoxysuccinyl peptides as highly potent and selective cathepsin B inhibitors”, FEBS LETTERS, vol. 421, 1998, pp. 80-82.PUB | DOI | WoS | PubMed | Europe PMC
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1997 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403882N. Schaschke, et al., “E-64 analogues as inhibitors of cathepsin B. On the role of the absolute configuration of the epoxysuccinyl group”, BIOORGANIC & MEDICINAL CHEMISTRY, vol. 5, 1997, pp. 1789-1797.PUB | DOI | WoS | PubMed | Europe PMC
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1996 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2403889N. Schaschke, et al., “Cyclodextrins as templates for the presentation of protease inhibitors”, FEBS LETTERS, vol. 391, 1996, pp. 297-301.PUB | DOI | WoS | PubMed | Europe PMC