Bivalent inhibition of beta-tryptase: Distance scan of neighboring subunits by dibasic inhibitors

Schaschke N, Dominik A, Matschiner G, Sommerhoff CP (2002)
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 12(6): 985-988.

Zeitschriftenaufsatz | Veröffentlicht | Englisch
 
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DOI
Autor*in
Schaschke, NorbertUniBi; Dominik, A; Matschiner, G; Sommerhoff, CP
Einrichtung
Fakultät für Chemie > Organische Chemie III
Erscheinungsjahr
2002
Zeitschriftentitel
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Band
12
Ausgabe
6
Seite(n)
985-988
ISSN
0960-894X
Page URI
https://pub.uni-bielefeld.de/record/2403828

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Schaschke N, Dominik A, Matschiner G, Sommerhoff CP. Bivalent inhibition of beta-tryptase: Distance scan of neighboring subunits by dibasic inhibitors. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. 2002;12(6):985-988.
Schaschke, N., Dominik, A., Matschiner, G., & Sommerhoff, C. P. (2002). Bivalent inhibition of beta-tryptase: Distance scan of neighboring subunits by dibasic inhibitors. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 12(6), 985-988. https://doi.org/10.1016/S0960-894X(02)00063-X
Schaschke, Norbert, Dominik, A, Matschiner, G, and Sommerhoff, CP. 2002. “Bivalent inhibition of beta-tryptase: Distance scan of neighboring subunits by dibasic inhibitors”. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 12 (6): 985-988.
Schaschke, N., Dominik, A., Matschiner, G., and Sommerhoff, C. P. (2002). Bivalent inhibition of beta-tryptase: Distance scan of neighboring subunits by dibasic inhibitors. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 12, 985-988.
Schaschke, N., et al., 2002. Bivalent inhibition of beta-tryptase: Distance scan of neighboring subunits by dibasic inhibitors. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 12(6), p 985-988.
N. Schaschke, et al., “Bivalent inhibition of beta-tryptase: Distance scan of neighboring subunits by dibasic inhibitors”, BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 12, 2002, pp. 985-988.
Schaschke, N., Dominik, A., Matschiner, G., Sommerhoff, C.P.: Bivalent inhibition of beta-tryptase: Distance scan of neighboring subunits by dibasic inhibitors. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. 12, 985-988 (2002).
Schaschke, Norbert, Dominik, A, Matschiner, G, and Sommerhoff, CP. “Bivalent inhibition of beta-tryptase: Distance scan of neighboring subunits by dibasic inhibitors”. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 12.6 (2002): 985-988.

15 Zitationen in Europe PMC

Daten bereitgestellt von Europe PubMed Central.

Target-Directed Self-Assembly of Homodimeric Drugs Against β-Tryptase.
Giardina SF, Werner DS, Pingle M, Foreman KW, Bergstrom DE, Arnold LD, Barany F., ACS Med Chem Lett 9(8), 2018
PMID: 30128075
A Novel, Nonpeptidic, Orally Active Bivalent Inhibitor of Human β-Tryptase.
Giardina SF, Werner DS, Pingle M, Bergstrom DE, Arnold LD, Barany F., Pharmacology 102(5-6), 2018
PMID: 30134249
Mast cell proteases as pharmacological targets.
Caughey GH., Eur J Pharmacol 778(), 2016
PMID: 25958181
Discovery of potent inhibitors of human β-tryptase from pre-equilibrated dynamic combinatorial libraries.
Jiang QQ, Sicking W, Ehlers M, Schmuck C., Chem Sci 6(3), 2015
PMID: 29163876
A new approach to inhibit human β-tryptase by protein surface binding of four-armed peptide ligands with two different sets of arms.
Jiang QQ, Bartsch L, Sicking W, Wich PR, Heider D, Hoffmann D, Schmuck C., Org Biomol Chem 11(10), 2013
PMID: 23358683
The arginine mimicking β-amino acid β³hPhe(3-H₂N-CH₂) as S1 ligand in cyclotheonamide-based β-tryptase inhibitors.
Janke D, Sommerhoff CP, Schaschke N., Bioorg Med Chem 19(23), 2011
PMID: 22047802
Engineered cystine knot miniproteins as potent inhibitors of human mast cell tryptase beta.
Sommerhoff CP, Avrutina O, Schmoldt HU, Gabrijelcic-Geiger D, Diederichsen U, Kolmar H., J Mol Biol 395(1), 2010
PMID: 19852971
Reversible and noncompetitive inhibition of beta-tryptase by protein surface binding of tetravalent peptide ligands identified from a combinatorial split-mix library.
Wich PR, Schmuck C., Angew Chem Int Ed Engl 49(24), 2010
PMID: 20432495
Mast cell tryptases and chymases in inflammation and host defense.
Caughey GH., Immunol Rev 217(), 2007
PMID: 17498057
Biology of mast cell tryptase. An inflammatory mediator.
Hallgren J, Pejler G., FEBS J 273(9), 2006
PMID: 16640553
Affinity chromatography of tryptases: design, synthesis and characterization of a novel matrix-bound bivalent inhibitor.
Schaschke N, Gabrijelcic-Geiger D, Dominik A, Sommerhoff CP., Chembiochem 6(1), 2005
PMID: 15593113
Combinatorial approaches towards the discovery of new tryptase inhibitors.
del Fresno M, Fernández-Forner D, Miralpeix M, Segarra V, Ryder H, Royo M, Albericio F., Bioorg Med Chem Lett 15(6), 2005
PMID: 15745817
Inhibition of human beta-tryptase by Bowman-Birk inhibitor derived peptides: creation of a new tri-functional inhibitor.
Scarpi D, McBride JD, Leatherbarrow RJ., Bioorg Med Chem 12(23), 2004
PMID: 15519150
Design of bivalent ligands using hydrogen bond linkers: synthesis and evaluation of inhibitors for human beta-tryptase.
Vaz RJ, Gao Z, Pribish J, Chen X, Levell J, Davis L, Albert E, Brollo M, Ugolini A, Cramer DM, Cairns J, Sides K, Liu F, Kwong J, Kang J, Rebello S, Elliot M, Lim H, Chellaraj V, Singleton RW, Li Y., Bioorg Med Chem Lett 14(24), 2004
PMID: 15546728
Potent bivalent inhibition of human tryptase-beta by a synthetic inhibitor.
Selwood T, Elrod KC, Schechter NM., Biol Chem 384(12), 2003
PMID: 14719803

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