48 Publikationen
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2023 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2981846A novel homozygous missense variant in ARSK causes MPS X, a new subtype of mucopolysaccharidosisPUB | DOI | WoS | PubMed | Europe PMC
Sun, Miao, A novel homozygous missense variant in ARSK causes MPS X, a new subtype of mucopolysaccharidosis. Genes & Diseases 11 (3). , 2023 -
2023 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 2988232Establishment of Blood Glycosidase Activities and their Excursions in SepsisPUB | WoS
Smith, Kathryn, Establishment of Blood Glycosidase Activities and their Excursions in Sepsis. 33 (11). Cary, 2023 -
2022 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2962857
The Human Ntn-Hydrolase Superfamily: Structure, Functions and PerspectivesPUB | PDF | DOI | Download (ext.) | WoS | PubMed | Europe PMC
Linhorst, Arne, The Human Ntn-Hydrolase Superfamily: Structure, Functions and Perspectives. Cells 11 (10). , 2022 -
2022 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 2967253Establishment of Blood Glycosidase Activities and their Excursions in SepsisPUB | WoS
Smith, Kathryn, Establishment of Blood Glycosidase Activities and their Excursions in Sepsis. 32 (11). Cary, 2022 -
2022 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2965167Establishment of blood glycosidase activities and their excursions in sepsisPUB | DOI | PubMed | Europe PMC
Haslund-Gourley, Benjamin S, Establishment of blood glycosidase activities and their excursions in sepsis. PNAS Nexus 1 (3). , 2022 -
2021 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 2961637Excursions of blood glycosidase activities in the pathogenesis and prognosis of SepsisPUB | DOI | WoS
Aziz, Peter V., Excursions of blood glycosidase activities in the pathogenesis and prognosis of Sepsis. 31 (12). Cary, 2021 -
2021 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2960244
Novel subtype of mucopolysaccharidosis caused by arylsulfatase K (ARSK) deficiencyPUB | PDF | DOI | WoS | PubMed | Europe PMC
Verheyen, Sarah, Novel subtype of mucopolysaccharidosis caused by arylsulfatase K (ARSK) deficiency. Journal of Medical Genetics (). , 2021 -
2021 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2956816Decoding the consecutive lysosomal degradation of 3-O-sulfate containing heparan sulfate by Arylsulfatase G (ARSG)PUB | DOI | WoS | PubMed | Europe PMC
Kowalewski, Björn, Decoding the consecutive lysosomal degradation of 3-O-sulfate containing heparan sulfate by Arylsulfatase G (ARSG). Biochemical Journal (). , 2021 -
2020 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 2946513Altered glycosidase Activities at Physiological pH in the Pathogenesis of SepsisPUB | DOI | WoS
Aziz, Peter, Altered glycosidase Activities at Physiological pH in the Pathogenesis of Sepsis. FASEB JOURNAL 34 (S1). Hoboken, 2020 -
2020 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2948390Lysosomal sulfatases: a growing family*PUB | DOI | WoS | PubMed | Europe PMC
Lübke, Torben, Lysosomal sulfatases: a growing family*. Biochemical Journal 477 (20). , 2020 -
2020 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2945876Arylsulfatase K inactivation causes mucopolysaccharidosis due to deficient glucuronate desulfation of heparan and chondroitin sulfatePUB | DOI | WoS | PubMed | Europe PMC
Trabszo, Christof, Arylsulfatase K inactivation causes mucopolysaccharidosis due to deficient glucuronate desulfation of heparan and chondroitin sulfate. Biochemical Journal (). , 2020 -
2019 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2937243Heparan Sulfate-Editing Extracellular Sulfatases Enhance Vascular Endothelial Growth Factor Bioavailability for Ischemic Heart RepairPUB | DOI | WoS | PubMed | Europe PMC
Korf-Klingebiel, Mortimer, Heparan Sulfate-Editing Extracellular Sulfatases Enhance Vascular Endothelial Growth Factor Bioavailability for Ischemic Heart Repair. Circulation research 125 (9). , 2019 -
2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2920271Sensorimotor and Neurocognitive Dysfunctions Parallel Early Telencephalic Neuropathology in Fucosidosis MicePUB | DOI | WoS | PubMed | Europe PMC
Stroobants, Stijn, Sensorimotor and Neurocognitive Dysfunctions Parallel Early Telencephalic Neuropathology in Fucosidosis Mice. FRONTIERS IN BEHAVIORAL NEUROSCIENCE 12 (). , 2018 -
2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2909150Mice, double deficient in lysosomal serine carboxypeptidases Scpep1 and Cathepsin A develop the hyperproliferative vesicular corneal dystrophy and hypertrophic skin thickeningsPUB | DOI | WoS | PubMed | Europe PMC
Pan, Xuefang, Mice, double deficient in lysosomal serine carboxypeptidases Scpep1 and Cathepsin A develop the hyperproliferative vesicular corneal dystrophy and hypertrophic skin thickenings. PLoS One 12 (2). , 2017 -
2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2908778Arylsulfatase K is the Lysosomal 2-Sulfoglucuronate SulfatasePUB | DOI | WoS | PubMed | Europe PMC
Dhamale, Omkar P., Arylsulfatase K is the Lysosomal 2-Sulfoglucuronate Sulfatase. ACS Chemical Biology 12 (2). , 2017 -
2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2905616
A mouse model for fucosidosis recapitulates storage pathology and neurological features of the milder form of the human diseasePUB | PDF | DOI | WoS | PubMed | Europe PMC
Wolf, Heike, A mouse model for fucosidosis recapitulates storage pathology and neurological features of the milder form of the human disease. Disease Models & Mechanisms 9 (9). , 2016 -
2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2658538
Loss of lysosomal membrane protein NCU-G1 in mice results in spontaneous liver fibrosis with accumulation of lipofuscin and iron in Kupffer cellsPUB | PDF | DOI | WoS | PubMed | Europe PMC
Kong, Xiang Yi, Loss of lysosomal membrane protein NCU-G1 in mice results in spontaneous liver fibrosis with accumulation of lipofuscin and iron in Kupffer cells. Disease Models & Mechanisms 7 (3). , 2014 -
2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2672894
Serine carboxypeptidase SCPEP1 and Cathepsin A play complementary roles in regulation of vasoconstriction via inactivation of endothelin-1PUB | PDF | DOI | WoS | PubMed | Europe PMC
Pan, Xuefang, Serine carboxypeptidase SCPEP1 and Cathepsin A play complementary roles in regulation of vasoconstriction via inactivation of endothelin-1. PLoS genetics 10 (2). , 2014 -
2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2699273Molecular Characterization of Arylsulfatase G: EXPRESSION, PROCESSING, GLYCOSYLATION, TRANSPORT, AND ACTIVITYPUB | DOI | WoS | PubMed | Europe PMC
Kowalewski, Björn, Molecular Characterization of Arylsulfatase G: EXPRESSION, PROCESSING, GLYCOSYLATION, TRANSPORT, AND ACTIVITY. The Journal of biological chemistry 289 (40). , 2014 -
2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2623550Arylsulfatase K, a Novel Lysosomal SulfatasePUB | DOI | WoS | PubMed | Europe PMC
Wiegmann, Elena, Arylsulfatase K, a Novel Lysosomal Sulfatase. Journal of Biological Chemistry 288 (42). , 2013 -
2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2623533Cooperation of binding sites at the hydrophilic domain of cell-surface sulfatase Sulf1 allows for dynamic interaction of the enzyme with its substrate heparan sulfatePUB | DOI | WoS | PubMed | Europe PMC
Milz, Fabian, Cooperation of binding sites at the hydrophilic domain of cell-surface sulfatase Sulf1 allows for dynamic interaction of the enzyme with its substrate heparan sulfate. Biochim Biophys Acta 1830 (11). , 2013 -
2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2471754Mannose 6 dephosphorylation of lysosomal proteins mediated by Acid phosphatases acp2 and acp5PUB | DOI | WoS | PubMed | Europe PMC
Makrypidi, Georgia, Mannose 6 dephosphorylation of lysosomal proteins mediated by Acid phosphatases acp2 and acp5. Molecular and cellular biology 32 (4). , 2012 -
2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2529586Lysosomal dysfunction causes neurodegeneration in mucolipidosis II 'knock-in' micePUB | DOI | WoS | PubMed | Europe PMC
Kollmann, K, Lysosomal dysfunction causes neurodegeneration in mucolipidosis II 'knock-in' mice. Brain 135 (9). , 2012 -
2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2494022Arylsulfatase G Inactivation Causes Loss of Heparan Sulfate 3-O-Sulfatase Activity and Mucopolysaccharidosis in MicePUB | DOI | WoS | PubMed | Europe PMC
Kowalewski, Björn, Arylsulfatase G Inactivation Causes Loss of Heparan Sulfate 3-O-Sulfatase Activity and Mucopolysaccharidosis in Mice. Proc. Natl. Acad. Sci. USA 109 (26). , 2012 -
2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1940515Cerebellar alterations and gait defects as therapeutic outcome measures for enzyme replacement therapy in alpha-mannosidosisPUB | DOI | WoS | PubMed | Europe PMC
Damme, Markus, Cerebellar alterations and gait defects as therapeutic outcome measures for enzyme replacement therapy in alpha-mannosidosis. Journal of Neuropathology & Experimental Neurology 70 (1). , 2011 -
2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2352585Disrupted in renal carcinoma 2 (DIRC2), a novel transporter of the lysosomal membrane, is proteolytically processed by cathepsin L.PUB | DOI | WoS | PubMed | Europe PMC
Savalas, LR, Disrupted in renal carcinoma 2 (DIRC2), a novel transporter of the lysosomal membrane, is proteolytically processed by cathepsin L.. Biochemical Journal 436 (1). , 2011 -
2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1939855Erratum to: Rhesus macaque MHC class I molecules show differential subcellular localizationsPUB | DOI | WoS | PubMed | Europe PMC
Rosner, Cornelia, Erratum to: Rhesus macaque MHC class I molecules show differential subcellular localizations. Immunogenetics 62 (6). , 2010 -
2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2776186Rhesus macaque MHC class I molecules show differential subcellular localizationsPUB | DOI | WoS | PubMed | Europe PMC
Rosner, Cornelia, Rhesus macaque MHC class I molecules show differential subcellular localizations. Immunogenetics 62 (3). , 2010 -
2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1939885Mannose phosphorylation in health and diseasePUB | DOI | WoS | PubMed | Europe PMC
Kollmann, Katrin, Mannose phosphorylation in health and disease. European Journal of Cell Biology 89 (1). , 2010 -
2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1902203Impaired lysosomal trimming of N-linked oligosaccharides leads to hyperglycosylation of native lysosomal proteins in mice with alpha-mannosidosis.PUB | DOI | WoS | PubMed | Europe PMC
Damme, Markus, Impaired lysosomal trimming of N-linked oligosaccharides leads to hyperglycosylation of native lysosomal proteins in mice with alpha-mannosidosis.. Molecular and Cellular Biology 30 (1). , 2010 -
2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1939923Initial insight into the function of the lysosomal 66.3 kDa protein from mouse by means of X-ray crystallographyPUB | DOI | WoS | PubMed | Europe PMC
Lakomek, Kristina, Initial insight into the function of the lysosomal 66.3 kDa protein from mouse by means of X-ray crystallography. BMC Structural Biology 9 (1). , 2009 -
2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1902143NCU-G1 is a highly glycosylated integral membrane protein of the lysosome.PUB | DOI | WoS | PubMed | Europe PMC
Schieweck, Oliver, NCU-G1 is a highly glycosylated integral membrane protein of the lysosome.. Biochemical Journal 422 (1). , 2009 -
2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1939981Proteomics of the lysosomePUB | DOI | WoS | PubMed | Europe PMC
Lübke, Torben, Proteomics of the lysosome. Biochimica et Biophysica Acta 1793 (4). , 2009 -
2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1940533Molecular characterization and gene disruption of mouse lysosomal putative serine carboxypeptidase 1PUB | DOI | WoS | PubMed | Europe PMC
Kollmann, Katrin, Molecular characterization and gene disruption of mouse lysosomal putative serine carboxypeptidase 1. Febs Journal 276 (5). , 2009 -
2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1939939De novo sulfur SAD phasing of the lysosomal 66.3 kDa protein from mousePUB | DOI | WoS | PubMed | Europe PMC
Lakomek, Kristina, De novo sulfur SAD phasing of the lysosomal 66.3 kDa protein from mouse. Acta Crystallographica Section D 65 (3). , 2009 -
2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1939993Mutational analysis of the HGSNAT gene in Italian patients with mucopolysaccharidosis IIIC (Sanfilippo C syndrome)PUB | DOI
Fedele, Anthony O., Mutational analysis of the HGSNAT gene in Italian patients with mucopolysaccharidosis IIIC (Sanfilippo C syndrome). Human Mutation 28 (5). , 2007 -
2007 | Zeitschriftenaufsatz | PUB-ID: 1940006Golgi GDP-fucose transporter-deficient mice mimic congenital disorder of glycosylation IIc/leukocyte adhesion deficiency IIPUB | DOI | WoS | PubMed | Europe PMC
Hellbusch, Christina, Golgi GDP-fucose transporter-deficient mice mimic congenital disorder of glycosylation IIc/leukocyte adhesion deficiency II. Journal of Biological Chemistry 282 (14). , 2007 -
2006 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1940030Molecular characterization of the hypothetical 66.3-kDa protein in mouse: lysosomal targeting, glycosylation, processing and tissue distributionPUB | DOI | WoS | PubMed | Europe PMC
Deuschl, Florian, Molecular characterization of the hypothetical 66.3-kDa protein in mouse: lysosomal targeting, glycosylation, processing and tissue distribution. Febs Letters 580 (24). , 2006 -
2006 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1940045Targeted disruption of the mouse phosphomannomutase 2 gene causes early embryonic lethalityPUB | DOI | WoS | PubMed | Europe PMC
Thiel, Christian, Targeted disruption of the mouse phosphomannomutase 2 gene causes early embryonic lethality. Molecular and Cellular Biology 26 (15). , 2006 -
2006 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1940057Mucolipidosis II is caused by mutations in GNPTA encoding the alpha/beta GlcNAc-1-phosphotransferasePUB | DOI | WoS | PubMed | Europe PMC
Tiede, Stephan, Mucolipidosis II is caused by mutations in GNPTA encoding the alpha/beta GlcNAc-1-phosphotransferase. Nature Medicine 11 (10). , 2006 -
2005 | Sammelwerksbeitrag | Veröffentlicht | PUB-ID: 1940182Lysosomal Proteome and TranscriptomePUB | DOI
Lübke, Torben, Lysosomal Proteome and Transcriptome. Lysosomes (). Georgetown, Texas, USA, 2005 -
2005 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1940072Identification of novel lysosomal matrix proteins by proteome analysisPUB | DOI | WoS | PubMed | Europe PMC
Kollmann, Katrin, Identification of novel lysosomal matrix proteins by proteome analysis. Proteomics 5 (15). , 2005 -
2002 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1940085The disintegrin/metalloprotease ADAM 10 is essential for Notch signalling but not for alpha-secretase activity in fibroblastsPUB | DOI | WoS | PubMed | Europe PMC
Hartmann, Dieter, The disintegrin/metalloprotease ADAM 10 is essential for Notch signalling but not for alpha-secretase activity in fibroblasts. Human Molecular Genetics 11 (21). , 2002 -
2002 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1940103Deficiency of UDP-galactose:N-acetylglucosamine beta-1,4-galactosyltransferase I causes the congenital disorder of glycosylation type IIdPUB | DOI | WoS | PubMed | Europe PMC
Hansske, Bengt, Deficiency of UDP-galactose:N-acetylglucosamine beta-1,4-galactosyltransferase I causes the congenital disorder of glycosylation type IId. Journal of Clinical Investigation 109 (6). , 2002 -
2001 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1940119Complementation cloning identifies CDG-IIc, a new type of congenital disorders of glycosylation, as a GDP-fucose transporter deficiencyPUB | DOI | WoS | PubMed | Europe PMC
Lübke, Torben, Complementation cloning identifies CDG-IIc, a new type of congenital disorders of glycosylation, as a GDP-fucose transporter deficiency. Nature Genetics 28 (1). , 2001 -
2001 | Dissertation | PUB-ID: 1940291Congenital Disorder of Glycosylation (CDG)-IIc: Eine retrovirale Expressionsklonierung identifiziert das CDG-IIc Syndrom (Leukozyten Adhäsionsdefekt II) als eine GDP-Fukose Transporter DefizienzPUB
Lübke, Torben, Congenital Disorder of Glycosylation (CDG)-IIc: Eine retrovirale Expressionsklonierung identifiziert das CDG-IIc Syndrom (Leukozyten Adhäsionsdefekt II) als eine GDP-Fukose Transporter Defizienz. (). Göttingen, Deutschland, 2001 -
2000 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1940146ModE-dependent molybdate regulation of the molybdenum cofactor operon moa in Escherichia coliPUB | DOI | WoS | PubMed | Europe PMC
Andersson, Lisa A., ModE-dependent molybdate regulation of the molybdenum cofactor operon moa in Escherichia coli. Journal of Bacteriology 182 (24). , 2000 -
1999 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1940173A new type of carbohydrate-deficient glycoprotein syndrome due to a decreased import of GDP-fucose into the golgiPUB | DOI | WoS | PubMed | Europe PMC
Lübke, Torben, A new type of carbohydrate-deficient glycoprotein syndrome due to a decreased import of GDP-fucose into the golgi. Journal of Biological Chemistry 274 (37). , 1999