48 Publikationen
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2023 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2981846Sun, M., et al., 2023. A novel homozygous missense variant in ARSK causes MPS X, a new subtype of mucopolysaccharidosis. Genes & Diseases, 11(3): 101025.PUB | DOI | WoS | PubMed | Europe PMC
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2022 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2962857Linhorst, A., & Lübke, T., 2022. The Human Ntn-Hydrolase Superfamily: Structure, Functions and Perspectives. Cells, 11(10): 1592.PUB | PDF | DOI | Download (ext.) | WoS | PubMed | Europe PMC
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2022 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2965167Haslund-Gourley, B.S., et al., 2022. Establishment of blood glycosidase activities and their excursions in sepsis. PNAS Nexus, 1(3): pgac113.PUB | DOI | PubMed | Europe PMC
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2021 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2956816Kowalewski, B., et al., 2021. Decoding the consecutive lysosomal degradation of 3-O-sulfate containing heparan sulfate by Arylsulfatase G (ARSG). Biochemical Journal.PUB | DOI | WoS | PubMed | Europe PMC
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2020 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2948390Lübke, T., & Damme, M., 2020. Lysosomal sulfatases: a growing family*. Biochemical Journal, 477(20), p 3963-3983.PUB | DOI | WoS | PubMed | Europe PMC
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2020 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2945876Trabszo, C., et al., 2020. Arylsulfatase K inactivation causes mucopolysaccharidosis due to deficient glucuronate desulfation of heparan and chondroitin sulfate. Biochemical Journal.PUB | DOI | WoS | PubMed | Europe PMC
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2019 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2937243Korf-Klingebiel, M., et al., 2019. Heparan Sulfate-Editing Extracellular Sulfatases Enhance Vascular Endothelial Growth Factor Bioavailability for Ischemic Heart Repair. Circulation research, 125(9), p 787-801.PUB | DOI | WoS | PubMed | Europe PMC
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2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2920271Stroobants, S., et al., 2018. Sensorimotor and Neurocognitive Dysfunctions Parallel Early Telencephalic Neuropathology in Fucosidosis Mice. FRONTIERS IN BEHAVIORAL NEUROSCIENCE, 12: 15.PUB | DOI | WoS | PubMed | Europe PMC
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2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2909150Pan, X., et al., 2017. Mice, double deficient in lysosomal serine carboxypeptidases Scpep1 and Cathepsin A develop the hyperproliferative vesicular corneal dystrophy and hypertrophic skin thickenings. PLoS One, 12(2): e0172854.PUB | DOI | WoS | PubMed | Europe PMC
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2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2908778Dhamale, O.P., et al., 2017. Arylsulfatase K is the Lysosomal 2-Sulfoglucuronate Sulfatase. ACS Chemical Biology, 12(2), p 367-373.PUB | DOI | WoS | PubMed | Europe PMC
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2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2905616Wolf, H., et al., 2016. A mouse model for fucosidosis recapitulates storage pathology and neurological features of the milder form of the human disease. Disease Models & Mechanisms, 9(9), p 1015-1028.PUB | PDF | DOI | WoS | PubMed | Europe PMC
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2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2658538Kong, X.Y., et al., 2014. Loss of lysosomal membrane protein NCU-G1 in mice results in spontaneous liver fibrosis with accumulation of lipofuscin and iron in Kupffer cells. Disease Models & Mechanisms, 7(3), p 351-362.PUB | PDF | DOI | WoS | PubMed | Europe PMC
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2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2672894Pan, X., et al., 2014. Serine carboxypeptidase SCPEP1 and Cathepsin A play complementary roles in regulation of vasoconstriction via inactivation of endothelin-1. PLoS genetics, 10(2): e1004146.PUB | PDF | DOI | WoS | PubMed | Europe PMC
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2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2699273Kowalewski, B., et al., 2014. Molecular Characterization of Arylsulfatase G: EXPRESSION, PROCESSING, GLYCOSYLATION, TRANSPORT, AND ACTIVITY. The Journal of biological chemistry, 289(40), p 27992-28005.PUB | DOI | WoS | PubMed | Europe PMC
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2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2623550Wiegmann, E., et al., 2013. Arylsulfatase K, a Novel Lysosomal Sulfatase. Journal of Biological Chemistry, 288(42), p 30019-30028.PUB | DOI | WoS | PubMed | Europe PMC
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2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2623533Milz, F., et al., 2013. Cooperation of binding sites at the hydrophilic domain of cell-surface sulfatase Sulf1 allows for dynamic interaction of the enzyme with its substrate heparan sulfate. Biochim Biophys Acta, 1830(11), p 5287-5298.PUB | DOI | WoS | PubMed | Europe PMC
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2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2471754Makrypidi, G., et al., 2012. Mannose 6 dephosphorylation of lysosomal proteins mediated by Acid phosphatases acp2 and acp5. Molecular and cellular biology, 32(4), p 774-782.PUB | DOI | WoS | PubMed | Europe PMC
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2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2529586Kollmann, K., et al., 2012. Lysosomal dysfunction causes neurodegeneration in mucolipidosis II 'knock-in' mice. Brain, 135(9), p 2661-2675.PUB | DOI | WoS | PubMed | Europe PMC
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2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2494022Kowalewski, B., et al., 2012. Arylsulfatase G Inactivation Causes Loss of Heparan Sulfate 3-O-Sulfatase Activity and Mucopolysaccharidosis in Mice. Proc. Natl. Acad. Sci. USA, 109(26), p 10310-10315.PUB | DOI | WoS | PubMed | Europe PMC
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2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1940515Damme, M., et al., 2011. Cerebellar alterations and gait defects as therapeutic outcome measures for enzyme replacement therapy in alpha-mannosidosis. Journal of Neuropathology & Experimental Neurology, 70(1), p 83-94.PUB | DOI | WoS | PubMed | Europe PMC
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2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2352585Savalas, L.R., et al., 2011. Disrupted in renal carcinoma 2 (DIRC2), a novel transporter of the lysosomal membrane, is proteolytically processed by cathepsin L. Biochemical Journal, 436(1), p 113-121.PUB | DOI | WoS | PubMed | Europe PMC
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2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1939855Rosner, C., et al., 2010. Erratum to: Rhesus macaque MHC class I molecules show differential subcellular localizations. Immunogenetics, 62(6), p 409-418.PUB | DOI | WoS | PubMed | Europe PMC
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2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2776186Rosner, C., et al., 2010. Rhesus macaque MHC class I molecules show differential subcellular localizations. Immunogenetics, 62(3), p 149-158.PUB | DOI | WoS | PubMed | Europe PMC
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2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1939885Kollmann, K., et al., 2010. Mannose phosphorylation in health and disease. European Journal of Cell Biology, 89(1), p 117-123.PUB | DOI | WoS | PubMed | Europe PMC
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2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1902203Damme, M., et al., 2010. Impaired lysosomal trimming of N-linked oligosaccharides leads to hyperglycosylation of native lysosomal proteins in mice with alpha-mannosidosis. Molecular and Cellular Biology, 30(1), p 273-283.PUB | DOI | WoS | PubMed | Europe PMC
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2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1939923Lakomek, K., et al., 2009. Initial insight into the function of the lysosomal 66.3 kDa protein from mouse by means of X-ray crystallography. BMC Structural Biology, 9(1), p 56-72.PUB | DOI | WoS | PubMed | Europe PMC
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2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1902143Schieweck, O., et al., 2009. NCU-G1 is a highly glycosylated integral membrane protein of the lysosome. Biochemical Journal, 422(1), p 83-90.PUB | DOI | WoS | PubMed | Europe PMC
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2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1939981Lübke, T., Lobel, P., & Sleat, D.E., 2009. Proteomics of the lysosome. Biochimica et Biophysica Acta, 1793(4), p 625-635.PUB | DOI | WoS | PubMed | Europe PMC
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2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1940533Kollmann, K., et al., 2009. Molecular characterization and gene disruption of mouse lysosomal putative serine carboxypeptidase 1. Febs Journal, 276(5), p 1356-1369.PUB | DOI | WoS | PubMed | Europe PMC
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2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1939939Lakomek, K., et al., 2009. De novo sulfur SAD phasing of the lysosomal 66.3 kDa protein from mouse. Acta Crystallographica Section D, 65(3), p 220-228.PUB | DOI | WoS | PubMed | Europe PMC
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2007 | Zeitschriftenaufsatz | PUB-ID: 1940006Hellbusch, C., et al., 2007. Golgi GDP-fucose transporter-deficient mice mimic congenital disorder of glycosylation IIc/leukocyte adhesion deficiency II. Journal of Biological Chemistry, 282(14), p 10762-10772.PUB | DOI | WoS | PubMed | Europe PMC
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2006 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1940030Deuschl, F., et al., 2006. Molecular characterization of the hypothetical 66.3-kDa protein in mouse: lysosomal targeting, glycosylation, processing and tissue distribution. Febs Letters, 580(24), p 5747-5752.PUB | DOI | WoS | PubMed | Europe PMC
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2006 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1940045Thiel, C., et al., 2006. Targeted disruption of the mouse phosphomannomutase 2 gene causes early embryonic lethality. Molecular and Cellular Biology, 26(15), p 5615-5620.PUB | DOI | WoS | PubMed | Europe PMC
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2006 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1940057Tiede, S., et al., 2006. Mucolipidosis II is caused by mutations in GNPTA encoding the alpha/beta GlcNAc-1-phosphotransferase. Nature Medicine, 11(10), p 1109-1112.PUB | DOI | WoS | PubMed | Europe PMC
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2005 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1940072Kollmann, K., et al., 2005. Identification of novel lysosomal matrix proteins by proteome analysis. Proteomics, 5(15), p 3966-3978.PUB | DOI | WoS | PubMed | Europe PMC
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2002 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1940085Hartmann, D., et al., 2002. The disintegrin/metalloprotease ADAM 10 is essential for Notch signalling but not for alpha-secretase activity in fibroblasts. Human Molecular Genetics, 11(21), p 2615-2624.PUB | DOI | WoS | PubMed | Europe PMC
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2002 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1940103Hansske, B., et al., 2002. Deficiency of UDP-galactose:N-acetylglucosamine beta-1,4-galactosyltransferase I causes the congenital disorder of glycosylation type IId. Journal of Clinical Investigation, 109(6), p 725-733.PUB | DOI | WoS | PubMed | Europe PMC
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2001 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1940119Lübke, T., et al., 2001. Complementation cloning identifies CDG-IIc, a new type of congenital disorders of glycosylation, as a GDP-fucose transporter deficiency. Nature Genetics, 28(1), p 73-76.PUB | DOI | WoS | PubMed | Europe PMC
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2001 | Dissertation | PUB-ID: 1940291Lübke, T., 2001. Congenital Disorder of Glycosylation (CDG)-IIc: Eine retrovirale Expressionsklonierung identifiziert das CDG-IIc Syndrom (Leukozyten Adhäsionsdefekt II) als eine GDP-Fukose Transporter Defizienz, Göttingen, Deutschland: Elektronische Dissertation der Georg-August-Universität Göttingen.PUB
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2000 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1940146Andersson, L.A., et al., 2000. ModE-dependent molybdate regulation of the molybdenum cofactor operon moa in Escherichia coli. Journal of Bacteriology, 182(24), p 7035-7043.PUB | DOI | WoS | PubMed | Europe PMC
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1999 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1940173Lübke, T., et al., 1999. A new type of carbohydrate-deficient glycoprotein syndrome due to a decreased import of GDP-fucose into the golgi. Journal of Biological Chemistry, 274(37), p 25986-25989.PUB | DOI | WoS | PubMed | Europe PMC