PUB - Publikationen an der Universität Bielefeld

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• [48]
  

  2023 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2981846

  Sun, M., Kaminsky, C. K., Deppe, P., Ilse, M. - B., Vaz, F. M., Plecko, B., Lübke, T., et al. (2023). A novel homozygous missense variant in ARSK causes MPS X, a new subtype of mucopolysaccharidosis. Genes & Diseases, 11(3), 101025. https://doi.org/10.1016/j.gendis.2023.06.003

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• [47]
  

  2023 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 2988232

  Smith, K., Haslund-Gourley, B. S., Aziz, P. V., Heithoff, D. M., Restagno, D., Fried, J. C., Ilse, M. - B., et al. (2023). Establishment of Blood Glycosidase Activities and their Excursions in Sepsis. Glycobiology, 33(11), 1016.

  PUB | WoS
   
• [46]
  

  2022 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2962857

  Linhorst, A., & Lübke, T. (2022). The Human Ntn-Hydrolase Superfamily: Structure, Functions and Perspectives. Cells, 11(10), 1592. https://doi.org/10.3390/cells11101592

  PUB | PDF | DOI | Download (ext.) | WoS | PubMed | Europe PMC
   
• [45]
  

  2022 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 2967253

  Smith, K., Haslund-Gourley, B. S., Aziz, P. V., Heithoff, D. M., Restagno, D., Fried, J. C., Ilse, M. - B., et al. (2022). Establishment of Blood Glycosidase Activities and their Excursions in Sepsis. Glycobiology , 32(11), 1034-1035.

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• [44]
  

  2022 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2965167

  Haslund-Gourley, B. S., Aziz, P. V., Heithoff, D. M., Restagno, D., Fried, J. C., Ilse, M. - B., Bäumges, H., et al. (2022). Establishment of blood glycosidase activities and their excursions in sepsis. PNAS Nexus, 1(3), pgac113. https://doi.org/10.1093/pnasnexus/pgac113

  PUB | DOI | PubMed | Europe PMC
   
• [43]
  

  2021 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 2961637

  Aziz, P. V., Lewis, B. J., Haslund-Gourley, B. S., Heithoff, D. M., Westman, J. S., Restagno, D., Fried, J. C., et al. (2021). Excursions of blood glycosidase activities in the pathogenesis and prognosis of Sepsis. Glycobiology , 31(12), 1700. https://doi.org/10.1093/glycob/cwab121

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• [42]
  

  2021 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2960244

  Verheyen, S., Blatterer, J., Speicher, M. R., Bhavani, G. S. L., Boons, G. - J., Ilse, M. - B., Andrae, D., et al. (2021). Novel subtype of mucopolysaccharidosis caused by arylsulfatase K (ARSK) deficiency. Journal of Medical Genetics, jmedgenet-2021-108061. https://doi.org/10.1136/jmedgenet-2021-108061

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• [41]
  

  2021 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2956816

  Kowalewski, B., Lange, H., Galle, S., Dierks, T., Lübke, T., & Damme, M. (2021). Decoding the consecutive lysosomal degradation of 3-O-sulfate containing heparan sulfate by Arylsulfatase G (ARSG). Biochemical Journal. https://doi.org/10.1042/BCJ20210415

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• [40]
  

  2020 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 2946513

  Aziz, P., Haslund-Gourley, B., Heithoff, D., Westman, J., Restagno, D., Lewis, B., Fried, J., et al. (2020). Altered glycosidase Activities at Physiological pH in the Pathogenesis of Sepsis. FASEB JOURNAL, 34 Hoboken: Wiley. https://doi.org/10.1096/fasebj.2020.34.s1.07166

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• [39]
  

  2020 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2948390

  Lübke, T., & Damme, M. (2020). Lysosomal sulfatases: a growing family*. Biochemical Journal, 477(20), 3963-3983. doi:10.1042/bcj20200586

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• [38]
  

  2020 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2945876

  Trabszo, C., Ramms, B., Chopra, P., Lüllmann-Rauch, R., Stroobants, S., Sproß, J., Jeschke, A., et al. (2020). Arylsulfatase K inactivation causes mucopolysaccharidosis due to deficient glucuronate desulfation of heparan and chondroitin sulfate. Biochemical Journal. doi:10.1042/bcj20200546

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• [37]
  

  2019 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2937243

  Korf-Klingebiel, M., Reboll, M. R., Grote, K., Schleiner, H., Wang, Y., Wu, X., Klede, S., et al. (2019). Heparan Sulfate-Editing Extracellular Sulfatases Enhance Vascular Endothelial Growth Factor Bioavailability for Ischemic Heart Repair. Circulation research, 125(9), 787-801. doi:10.1161/CIRCRESAHA.119.315023

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [36]
  

  2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2920271

  Stroobants, S., Wolf, H., Callaerts-Vegh, Z., Dierks, T., Lübke, T., & D'Hooge, R. (2018). Sensorimotor and Neurocognitive Dysfunctions Parallel Early Telencephalic Neuropathology in Fucosidosis Mice. FRONTIERS IN BEHAVIORAL NEUROSCIENCE, 12, 15. doi:10.3389/fnbeh.2018.00069

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• [35]
  

  2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2909150

  Pan, X., Wang, Y., Lübke, T., Hinek, A., & Pshezhetsky, A. V. (2017). Mice, double deficient in lysosomal serine carboxypeptidases Scpep1 and Cathepsin A develop the hyperproliferative vesicular corneal dystrophy and hypertrophic skin thickenings. PLoS One, 12(2), e0172854. doi:10.1371/journal.pone.0172854

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• [34]
  

  2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2908778

  Dhamale, O. P., Lawrence, R., Wiegmann, E., Shah, B. A., Al-Mafraji, K., Lamanna, W. C., Lübke, T., et al. (2017). Arylsulfatase K is the Lysosomal 2-Sulfoglucuronate Sulfatase. ACS Chemical Biology, 12(2), 367-373. doi:10.1021/acschembio.6b01033

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• [33]
  

  2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2905616

  Wolf, H., Damme, M., Stroobants, S., D'Hooge, R., Beck, H. C., Hermans-Borgmeyer, I., Lüllmann-Rauch, R., et al. (2016). A mouse model for fucosidosis recapitulates storage pathology and neurological features of the milder form of the human disease. Disease Models & Mechanisms, 9(9), 1015-1028. doi:10.1242/dmm.025122

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• [32]
  

  2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2658538

  Kong, X. Y., Nesset, C. K., Damme, M., Loeberg, E. - M., Lübke, T., Maehlen, J., Andersson, K. B., et al. (2014). Loss of lysosomal membrane protein NCU-G1 in mice results in spontaneous liver fibrosis with accumulation of lipofuscin and iron in Kupffer cells. Disease Models & Mechanisms, 7(3), 351-362. doi:10.1242/dmm.014050

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• [31]
  

  2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2672894

  Pan, X., Grigoryeva, L., Seyrantepe, V., Peng, J., Kollmann, K., Tremblay, J., Lavoie, J. L., et al. (2014). Serine carboxypeptidase SCPEP1 and Cathepsin A play complementary roles in regulation of vasoconstriction via inactivation of endothelin-1. PLoS genetics, 10(2), e1004146. doi:10.1371/journal.pgen.1004146

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• [30]
  

  2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2699273

  Kowalewski, B., Lübke, T., Kollmann, K., Braulke, T., Reinheckel, T., Dierks, T., & Damme, M. (2014). Molecular Characterization of Arylsulfatase G: EXPRESSION, PROCESSING, GLYCOSYLATION, TRANSPORT, AND ACTIVITY. The Journal of biological chemistry, 289(40), 27992-28005. doi:10.1074/jbc.M114.584144

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• [29]
  

  2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2623550

  Wiegmann, E., Westendorf, E., Kalus, I., Pringle, T. H., Lübke, T., & Dierks, T. (2013). Arylsulfatase K, a Novel Lysosomal Sulfatase. Journal of Biological Chemistry, 288(42), 30019-30028. doi:10.1074/jbc.M113.499541

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• [28]
  

  2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2623533

  Milz, F., Harder, A., Neuhaus, P., Breitkreuz-Korff, O., Walhorn, V., Lübke, T., Anselmetti, D., et al. (2013). Cooperation of binding sites at the hydrophilic domain of cell-surface sulfatase Sulf1 allows for dynamic interaction of the enzyme with its substrate heparan sulfate. Biochim Biophys Acta, 1830(11), 5287-5298. doi:10.1016/j.bbagen.2013.07.014

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• [27]
  

  2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2471754

  Makrypidi, G., Damme, M., Müller-Loennies, S., Trusch, M., Schmidt, B., Schlüter, H., Heeren, J., et al. (2012). Mannose 6 dephosphorylation of lysosomal proteins mediated by Acid phosphatases acp2 and acp5. Molecular and cellular biology, 32(4), 774-782. doi:10.1128/MCB.06195-11

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• [26]
  

  2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2529586

  Kollmann, K., Damme, M., Markmann, S., Morelle, W., Schweizer, M., Hermans-Borgmeyer, I., Rochert, A. K., et al. (2012). Lysosomal dysfunction causes neurodegeneration in mucolipidosis II 'knock-in' mice. Brain, 135(9), 2661-2675. doi:10.1093/brain/aws209

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• [25]
  

  2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2494022

  Kowalewski, B., Lamanna, W. C., Lawrence, R., Damme, M., Padva, M., Stroobants, S., Kalus, I., et al. (2012). Arylsulfatase G Inactivation Causes Loss of Heparan Sulfate 3-O-Sulfatase Activity and Mucopolysaccharidosis in Mice. Proc. Natl. Acad. Sci. USA, 109(26), 10310-10315. doi:10.1073/pnas.1202071109

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• [24]
  

  2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1940515

  Damme, M., Stroobants, S., Walkley, S. U., Lüllmann-Rauch, R., D'Hooge, R., Fogh, J., Saftig, P., et al. (2011). Cerebellar alterations and gait defects as therapeutic outcome measures for enzyme replacement therapy in alpha-mannosidosis. Journal of Neuropathology & Experimental Neurology, 70(1), 83-94. https://doi.org/10.1097/NEN.0b013e31820428fa

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• [23]
  

  2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2352585

  Savalas, L. R., Gasnier, B., Damme, M., Lübke, T., Wrocklage, C., Debacker, C., Jezeqou, A., et al. (2011). Disrupted in renal carcinoma 2 (DIRC2), a novel transporter of the lysosomal membrane, is proteolytically processed by cathepsin L. Biochemical Journal, 436(1), 113-121. https://doi.org/10.1042/BJ20101672

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• [22]
  

  2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1939855

  Rosner, C., Kruse, P. H., Lübke, T., & Walter, L. (2010). Erratum to: Rhesus macaque MHC class I molecules show differential subcellular localizations. Immunogenetics, 62(6), 409-418. https://doi.org/10.1007/s00251-010-0447-y

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• [21]
  

  2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2776186

  Rosner, C., Kruse, P. H., Lübke, T., & Walter, L. (2010). Rhesus macaque MHC class I molecules show differential subcellular localizations. Immunogenetics, 62(3), 149-158. https://doi.org/10.1007/s00251-010-0424-5

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• [20]
  

  2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1939885

  Kollmann, K., Pohl, S., Marschner, K., Encarnacao, M., Sakwa, I., Tiede, S., Poorthuis, B. J., et al. (2010). Mannose phosphorylation in health and disease. European Journal of Cell Biology, 89(1), 117-123. https://doi.org/10.1016/j.ejcb.2009.10.008

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• [19]
  

  2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1902203

  Damme, M., Morelle, W., Schmidt, B., Andersson, C., Fogh, J., Michalski, J. - C., & Lübke, T. (2010). Impaired lysosomal trimming of N-linked oligosaccharides leads to hyperglycosylation of native lysosomal proteins in mice with alpha-mannosidosis. Molecular and Cellular Biology, 30(1), 273-283. https://doi.org/10.1128/MCB.01143-09

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• [18]
  

  2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1939923

  Lakomek, K., Dickmanns, A., Kettwig, M., Urlaub, H., Ficner, R., & Lübke, T. (2009). Initial insight into the function of the lysosomal 66.3 kDa protein from mouse by means of X-ray crystallography. BMC Structural Biology, 9(1), 56-72. https://doi.org/10.1186/1472-6807-9-56

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• [17]
  

  2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1902143

  Schieweck, O., Damme, M., Schröder, B., Hasilik, A., Schmidt, B., & Lübke, T. (2009). NCU-G1 is a highly glycosylated integral membrane protein of the lysosome. Biochemical Journal, 422(1), 83-90. https://doi.org/10.1042/BJ20090567

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• [16]
  

  2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1939981

  Lübke, T., Lobel, P., & Sleat, D. E. (2009). Proteomics of the lysosome. Biochimica et Biophysica Acta, 1793(4), 625-635. https://doi.org/10.1016/j.bbamcr.2008.09.018

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• [15]
  

  2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1940533

  Kollmann, K., Damme, M., Deuschl, F., Kahle, J., D'Hooge, R., Lüllmann-Rauch, R., & Lübke, T. (2009). Molecular characterization and gene disruption of mouse lysosomal putative serine carboxypeptidase 1. Febs Journal, 276(5), 1356-1369. https://doi.org/10.1111/j.1742-4658.2009.06877.x

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• [14]
  

  2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1939939

  Lakomek, K., Dickmanns, A., Mueller, U., Kollmann, K., Deuschl, F., Berndt, A., Lübke, T., et al. (2009). De novo sulfur SAD phasing of the lysosomal 66.3 kDa protein from mouse. Acta Crystallographica Section D, 65(3), 220-228. https://doi.org/10.1107/s0907444908041814

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• [13]
  

  2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1939993

  Fedele, A. O., Filocamo, M., Di Rocco, M., Sersale, G., Lübke, T., di Natale, P., Cosma, M. P., et al. (2007). Mutational analysis of the HGSNAT gene in Italian patients with mucopolysaccharidosis IIIC (Sanfilippo C syndrome). Human Mutation, 28(5), 523. https://doi.org/10.1002/humu.9488

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• [12]
  

  2007 | Zeitschriftenaufsatz | PUB-ID: 1940006

  Hellbusch, C., Sperandio, M., Frommhold, D., Yakubenia, S., Wild, M. K., Popovici, D., Vestweber, D., et al. (2007). Golgi GDP-fucose transporter-deficient mice mimic congenital disorder of glycosylation IIc/leukocyte adhesion deficiency II. Journal of Biological Chemistry, 282(14), 10762-10772. https://doi.org/10.1074/jbc.M700314200

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• [11]
  

  2006 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1940030

  Deuschl, F., Kollmann, K., von Figura, K., & Lübke, T. (2006). Molecular characterization of the hypothetical 66.3-kDa protein in mouse: lysosomal targeting, glycosylation, processing and tissue distribution. Febs Letters, 580(24), 5747-5752. https://doi.org/10.1016/j.febslet.2006.09.029

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• [10]
  

  2006 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1940045

  Thiel, C., Lübke, T., Matthijs, G., von Figura, K., & Körner, C. (2006). Targeted disruption of the mouse phosphomannomutase 2 gene causes early embryonic lethality. Molecular and Cellular Biology, 26(15), 5615-5620. https://doi.org/10.1128/MCB.02391-05

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• [9]
  

  2006 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1940057

  Tiede, S., Storch, S., Lübke, T., Henrissat, B., Bargal, R., Raas-Rothschild, A., & Braulke, T. (2006). Mucolipidosis II is caused by mutations in GNPTA encoding the alpha/beta GlcNAc-1-phosphotransferase. Nature Medicine, 11(10), 1109-1112. https://doi.org/10.1038/nm1305

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• [8]
  

  2005 | Sammelwerksbeitrag | Veröffentlicht | PUB-ID: 1940182

  Lübke, T., & Landgrebe, J. (2005). Lysosomal Proteome and Transcriptome. In P. Saftig (Ed.), Lysosomes (pp. 130-143). Georgetown, Texas, USA: Landes Bioscience. https://doi.org/10.1007/0-387-28957-7_11

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• [7]
  

  2005 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1940072

  Kollmann, K., Mutenda, K. E., Balleininger, M., Eckermann, E., von Figura, K., Schmidt, B., & Lübke, T. (2005). Identification of novel lysosomal matrix proteins by proteome analysis. Proteomics, 5(15), 3966-3978. https://doi.org/10.1002/pmic.200401247

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• [6]
  

  2002 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1940085

  Hartmann, D., de Strooper, B., Serneels, L., Craessaerts, K., Herreman, A., Annaert, W., Umans, L., et al. (2002). The disintegrin/metalloprotease ADAM 10 is essential for Notch signalling but not for alpha-secretase activity in fibroblasts. Human Molecular Genetics, 11(21), 2615-2624. https://doi.org/10.1093/hmg/11.21.2615

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• [5]
  

  2002 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1940103

  Hansske, B., Thiel, C., Lübke, T., Hasilik, M., Höning, S., Peters, V., Heidemann, P. H., et al. (2002). Deficiency of UDP-galactose:N-acetylglucosamine beta-1,4-galactosyltransferase I causes the congenital disorder of glycosylation type IId. Journal of Clinical Investigation, 109(6), 725-733. https://doi.org/10.1172/JCI14010

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• [4]
  

  2001 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1940119

  Lübke, T., Marquardt, T., Etzioni, A., Hartmann, E., von Figura, K., & Körner, C. (2001). Complementation cloning identifies CDG-IIc, a new type of congenital disorders of glycosylation, as a GDP-fucose transporter deficiency. Nature Genetics, 28(1), 73-76. https://doi.org/10.1038/ng0501-73

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• [3]
  

  2001 | Dissertation | PUB-ID: 1940291

  Lübke, T. (2001). Congenital Disorder of Glycosylation (CDG)-IIc: Eine retrovirale Expressionsklonierung identifiziert das CDG-IIc Syndrom (Leukozyten Adhäsionsdefekt II) als eine GDP-Fukose Transporter Defizienz. Göttingen, Deutschland: Elektronische Dissertation der Georg-August-Universität Göttingen.

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• [2]
  

  2000 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1940146

  Andersson, L. A., McNairn, E., Lübke, T., Pau, R. N., & Boxer, D. H. (2000). ModE-dependent molybdate regulation of the molybdenum cofactor operon moa in Escherichia coli. Journal of Bacteriology, 182(24), 7035-7043. https://doi.org/10.1128/JB.182.24.7035-7043.2000

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• [1]
  

  1999 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1940173

  Lübke, T., Marquardt, T., von Figura, K., & Körner, C. (1999). A new type of carbohydrate-deficient glycoprotein syndrome due to a decreased import of GDP-fucose into the golgi. Journal of Biological Chemistry, 274(37), 25986-25989. https://doi.org/10.1074/jbc.274.37.25986

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