52 Publikationen
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2024 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2986115Rapöhn, M., Cyganek, L., Voigt, N., Hasenfuß, G., Lehnart, S. E., and Wegener, J. (2024). Non-invasive analysis of contractility during identical maturations revealed two phenotypes in ventricular but not in atrial iPSC-CM. American Journal of Physiology-Heart and Circulatory Physiology, 35.PUB | DOI
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2023 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984773Wegener, J., Mitronova, G. Y., ElShareif, L., Quentin, C., Belov, V., Pochechueva, T., Hasenfuss, G., Ackermann, L., and Lehnart, S. E. (2023). A dual-targeted drug inhibits cardiac ryanodine receptor Ca2+ leak but activates SERCA2a Ca uptake. Life Science Alliance 7:e202302278.PUB | PDF | DOI | Download (ext.)
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2023 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2984660Mitronova, G. Y., Quentin, C., Belov, V. N., Wegener, J., Kiszka, K. A., and Lehnart, S. E. (2023). 1,4-Benzothiazepines with Cyclopropanol Groups and Their Structural Analogues Exhibit Both RyR2-Stabilizing and SERCA2a-Stimulating Activities. Journal of Medicinal Chemistry.PUB | PDF | DOI
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2022 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984472Brandenburg, S., Pawlowitz, J., Steckmeister, V., Subramanian, H., Uhlenkamp, D., Scardigli, M., Mushtaq, M., Amlaz, S. I., Kohl, T., Wegener, J., et al. (2022). A junctional cAMP compartment regulates rapid Ca2+ signaling in atrial myocytes. Journal of Molecular and Cellular Cardiology 165, 141-157.PUB | PDF | DOI | Download (ext.)
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2022 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984471Vandewiele, F., Pironet, A., Jacobs, G., Kecskés, M., Wegener, J., Kerselaers, S., Hendrikx, L., Verelst, J., Philippaert, K., Oosterlinck, W., et al. (2022). TRPM4 inhibition by meclofenamate suppresses Ca2+-dependent triggered arrhythmias. European Heart Journal 43, 4195-4207.PUB | DOI
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2021 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984475Peper, J., Kownatzki-Danger, D., Weninger, G., Seibertz, F., Pronto, J. R. D., Sutanto, H., Pacheu-Grau, D., Hindmarsh, R., Brandenburg, S., Kohl, T., et al. (2021). Caveolin3 Stabilizes McT1-Mediated Lactate/Proton Transport in Cardiomyocytes. Circulation Research 128.PUB | DOI
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2021 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984474Berisha, F., Götz, K. R., Wegener, J., Brandenburg, S., Subramanian, H., Molina, C. E., Rüffer, A., Petersen, J., Bernhardt, A., Girdauskas, E., et al. (2021). cAMP Imaging at Ryanodine Receptors Reveals β -Adrenoceptor Driven Arrhythmias. Circulation Research 129, 81-94.PUB | DOI
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2021 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984473Wegener, J., Wagdi, A., Wagner, E., Katschinski, D. M., Hasenfuss, G., Bruegmann, T., and Lehnart, S. E. (2021). The RyR2-R2474S Mutation Sensitizes Cardiomyocytes and Hearts to Catecholaminergic Stress-Induced Oxidation of the Mitochondrial Glutathione Pool. Frontiers in Physiology 12.PUB | DOI
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2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2684327Dongmo, A. B., Nkeng-Efouet, P. A., Devkota, K. P., Wegener, J., Sewald, N., Wagner, H., and Vierling, W. (2014). Tetra-acetylajugasterone a new constituent of Vitex cienkowskii with vasorelaxant activity. Phytomedicine 21, 787-792.PUB | DOI | WoS | PubMed | Europe PMC
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2013 | Sammelwerksbeitrag | Veröffentlicht | PUB-ID: 2984481Hofmann, F., and Wegener, J. (2013). “cGMP-Dependent Protein Kinases (cGK)” in Guanylate Cyclase and Cyclic GMP. Methods and Protocols, Krieg, T., and Lukowski, R. eds. Methods in Molecular Biology (Totowa, NJ: Humana Press), 17-50.PUB | DOI
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2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984479Loga, F., Domes, K., Freichel, M., Flockerzi, V., Dietrich, A., Birnbaumer, L., Hofmann, F., and Wegener, J. (2013). The role of cGMP/cGKI signalling and Trpc channels in regulation of vascular tone. Cardiovascular Research 100, 280-287.PUB | DOI
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2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984483Blaich, A., Pahlavan, S., Tian, Q., Oberhofer, M., Poomvanicha, M., Lenhardt, P., Domes, K., Wegener, J., Moosmang, S., Ruppenthal, S., et al. (2012). Mutation of the Calmodulin Binding Motif IQ of the L-type Cav1.2 Ca2+ Channel to EQ Induces Dilated Cardiomyopathy and Death. Journal of Biological Chemistry 287, 22616-22625.PUB | PDF | DOI | Download (ext.)
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2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984482Brandmayr, J., Poomvanicha, M., Domes, K., Ding, J., Blaich, A., Wegener, J., Moosmang, S., and Hofmann, F. (2012). Deletion of the C-terminal Phosphorylation Sites in the Cardiac β-Subunit Does Not Affect the Basic β-Adrenergic Response of the Heart and the Cav1.2 Channel. Journal of Biological Chemistry 287, 22584-22592.PUB | PDF | DOI | Download (ext.)
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2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984487Poomvanicha, M., Wegener, J., Blaich, A., Fischer, S., Domes, K., Moosmang, S., and Hofmann, F. (2011). Facilitation and Ca2+-dependent Inactivation Are Modified by Mutation of the Cav1.2 Channel IQ Motif. Journal of Biological Chemistry 286, 26702-26707.PUB | PDF | DOI | Download (ext.)
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2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984486Domes, K., Ding, J., Lemke, T., Blaich, A., Wegener, J., Brandmayr, J., Moosmang, S., and Hofmann, F. (2011). Truncation of Murine Cav1.2 at Asp-1904 Results in Heart Failure after Birth. Journal of Biological Chemistry 286, 33863-33871.PUB | PDF | DOI | Download (ext.)
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2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984484Singh, A. K., Spieβberger, B., Zheng, W., Xiao, F., Lukowski, R., Wegener, J., Weinmeister, P., Saur, D., Klein, S., Schemann, M., et al. (2011). Neuronal cGMP kinase I is essential for stimulation of duodenal bicarbonate secretion by luminal acid. The FASEB Journal 26, 1745-1754.PUB | DOI
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2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984489Desch, M., Sigl, K., Hieke, B., Salb, K., Kees, F., Bernhard, D., Jochim, A., Spiessberger, B., Höcherl, K., Feil, R., et al. (2010). IRAG determines nitric oxide- and atrial natriuretic peptide-mediated smooth muscle relaxation. Cardiovascular Research 86, 496-505.PUB | DOI
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2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2985980Frei, E., Huster, M., Smital, P., Schlossmann, J., Hofmann, F., and Wegener, J. (2009). Calcium-dependent and calcium-independent inhibition of contraction by cGMP/cGKI in intestinal smooth muscle. American Journal of Physiology-Gastrointestinal and Liver Physiology 297, G834-G839.PUB | DOI
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2007 | Sammelwerksbeitrag | Veröffentlicht | PUB-ID: 2984493Moosmang, S., Kleppisch, T., Wegener, J., Welling, A., and Hofmann, F. (2007). “Analysis of Calcium Channels by Conditional Mutagenesis” in Conditional Mutagenesis: An Approach to Disease Models, Feil, R., and Metzger, D. eds. Handbook of Experimental Pharmacology (Berlin, Heidelberg: Springer Berlin Heidelberg), 469-490.PUB | DOI
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2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984492Angstenberger, M., Wegener, J., Pichler, B. J., Judenhofer, M. S., Feil, S., Alberti, S., Feil, R., and Nordheim, A. (2007). Severe Intestinal Obstruction on Induced Smooth Muscle–Specific Ablation of the Transcription Factor SRF in Adult Mice. Gastroenterology 133, 1948-1959.PUB | DOI
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2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984491Weber, S., Bernhard, D., Lukowski, R., Weinmeister, P., Wörner, R., Wegener, J., Valtcheva, N., Feil, S., Schlossmann, J., Hofmann, F., et al. (2007). Rescue of cGMP Kinase I Knockout Mice by Smooth Muscle–Specific Expression of Either Isozyme. Circulation Research 101, 1096-1103.PUB | DOI
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2006 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984495Wegener, J., Schulla, V., Koller, A., Klugbauer, N., Feil, R., Hofmann, F., Wegener, J. W., Schulla, V., Koller, A., Klugbauer, N., et al. (2006). Control of intestinal motility by the Ca 1.2 L‐type calcium channel in mice. The FASEB Journal 20, 1260-1262.PUB | DOI
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2005 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984496Welling, A., Hofmann, F., and Wegener, J. (2005). Inhibition of L-Type Ca 1.2 Ca Channels by 2,(4-Morpholinyl)-8-phenyl-4 -1-benzopyran-4-one (LY294002) and 2-[1-(3-Dimethyl-aminopropyl)-5-methoxyindol-3-yl]-3-(1 -indol-3-yl) Maleimide (Gö6983). Molecular Pharmacology 67, 541-544.PUB | DOI
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2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984498Wegener, J., Schulla, V., Lee, T. ‐S., Koller, A., Feil, S., Feil, R., Kleppisch, T., Klugbauer, N., Moosmang, S., Welling, A., et al. (2004). An essential role of Ca 1.2 L‐type calcium channel for urinary bladder function. The FASEB Journal 18, 1159-1161.PUB | DOI
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2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984497Geiselhöringer, A., Werner, M., Sigl, K., Smital, P., Wörner, R., Acheo, L., Stieber, J., Weinmeister, P., Feil, R., Feil, S., et al. (2004). IRAG is essential for relaxation of receptor-triggered smooth muscle contraction by cGMP kinase. The EMBO Journal 23, 4222-4231.PUB | DOI
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2003 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984499Moosmang, S., Schulla, V., Welling, A., Feil, R., Feil, S., Wegener, J., Hofmann, F., and Klugbauer, N. (2003). Dominant role of smooth muscle L-type calcium channel Cav1.2 for blood pressure regulation. The EMBO Journal 22, 6027-6034.PUB | DOI
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2002 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984503Wegener, J., Nawrath, H., Wolfsgruber, W., Kühbandner, S., Werner, C., Hofmann, F., and Feil, R. (2002). cGMP-Dependent Protein Kinase I Mediates the Negative Inotropic Effect of cGMP in the Murine Myocardium. Circulation Research 90, 18-20.PUB | DOI
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2001 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984504Budu, C. E., Balas, N., Nawrath, H., Wegener, J., and Shainberg, A. (2001). Increased Cardiac Alpha-1-Adrenoceptor Density in Rats Following Treatment with Amiodarone. Journal of Basic and Clinical Physiology and Pharmacology 12, 33-48.PUB | DOI
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2000 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984505Nawrath, H., Wegener, J., Rupp, J., Habermeier, A., and Closs, E. I. (2000). Voltage dependence of -arginine transport by hCAT-2A and hCAT-2B expressed in oocytes from. American Journal of Physiology-Cell Physiology 279, C1336-C1344.PUB | DOI
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1999 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984507Seitz, S., Wegener, J., Rupp, J., Watanabe, M., Jost, A., Gerhard, R., Shainberg, A., Ochi, R., and Nawrath, H. (1999). Involvement of K+ channels in the relaxant effects of YC-1 in vascular smooth muscle. European Journal of Pharmacology 382, 11-18.PUB | DOI
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1993 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984640Wegener, J., Boekhoff, I., Tareilus, E., and Breer, H. (1993). Olfactory signalling in antennal receptor neurones of the locust (Locusta migratoria). Journal of Insect Physiology 39, 153-163.PUB | DOI | Download (ext.)
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