Hypothyroidism does not affect the dihydropyridine sensitivity of precontracted murine uterus
Wegener J, Lee M, Hofmann F (2003)
Canadian Journal of Physiology and Pharmacology 81(9): 890-893.
Zeitschriftenaufsatz
| Veröffentlicht | Englisch
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Autor*in
Wegener, JörgUniBi
;
Lee, Matthias;
Hofmann, Franz
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Abstract / Bemerkung
Thyroid hormones are known to influence various processes of cell differentiation. Recently, it was reported that hypothyroidism reduces the sensitivity to Ca2+-channel antagonists in the rat uterus. We examined the sensitivity to dihydropyridines of the uterus from mice that had reduced thyroid hormone levels. Isradipine relaxed with the same potency precontracted uterine muscle strips from control and hypothyroid mice, independently from a pseudo-pregnant state. These results demonstrate that hypothyroidism does not change dihydropyridine sensitivity (i.e., the pattern of Ca2+-channel expression) in the murine uterus.Key words: uterus, smooth muscle, Ca2+channel, isradipine.
Erscheinungsjahr
2003
Zeitschriftentitel
Canadian Journal of Physiology and Pharmacology
Band
81
Ausgabe
9
Seite(n)
890-893
ISSN
0008-4212
eISSN
1205-7541
Page URI
https://pub.uni-bielefeld.de/record/2984500
Zitieren
Wegener J, Lee M, Hofmann F. Hypothyroidism does not affect the dihydropyridine sensitivity of precontracted murine uterus. Canadian Journal of Physiology and Pharmacology. 2003;81(9):890-893.
Wegener, J., Lee, M., & Hofmann, F. (2003). Hypothyroidism does not affect the dihydropyridine sensitivity of precontracted murine uterus. Canadian Journal of Physiology and Pharmacology, 81(9), 890-893. https://doi.org/10.1139/y03-090
Wegener, Jörg, Lee, Matthias, and Hofmann, Franz. 2003. “Hypothyroidism does not affect the dihydropyridine sensitivity of precontracted murine uterus”. Canadian Journal of Physiology and Pharmacology 81 (9): 890-893.
Wegener, J., Lee, M., and Hofmann, F. (2003). Hypothyroidism does not affect the dihydropyridine sensitivity of precontracted murine uterus. Canadian Journal of Physiology and Pharmacology 81, 890-893.
Wegener, J., Lee, M., & Hofmann, F., 2003. Hypothyroidism does not affect the dihydropyridine sensitivity of precontracted murine uterus. Canadian Journal of Physiology and Pharmacology, 81(9), p 890-893.
J. Wegener, M. Lee, and F. Hofmann, “Hypothyroidism does not affect the dihydropyridine sensitivity of precontracted murine uterus”, Canadian Journal of Physiology and Pharmacology, vol. 81, 2003, pp. 890-893.
Wegener, J., Lee, M., Hofmann, F.: Hypothyroidism does not affect the dihydropyridine sensitivity of precontracted murine uterus. Canadian Journal of Physiology and Pharmacology. 81, 890-893 (2003).
Wegener, Jörg, Lee, Matthias, and Hofmann, Franz. “Hypothyroidism does not affect the dihydropyridine sensitivity of precontracted murine uterus”. Canadian Journal of Physiology and Pharmacology 81.9 (2003): 890-893.