Jörg Wegener

joerg.wegener@uni-bielefeld.de
ORCID logo https://orcid.org/0000-0002-8129-1537

PEVZ-ID
439914424

52 Publikationen

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  • [52]
    2024 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2986115
    M. Rapöhn, L. Cyganek, N. Voigt, G. Hasenfuß, S. E. Lehnart, and J. Wegener, “Non-invasive analysis of contractility during identical maturations revealed two phenotypes in ventricular but not in atrial iPSC-CM”, American Journal of Physiology-Heart and Circulatory Physiology, 2024, 35.
    PUB | DOI
     
  • [51]
    2023 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984773 OA
    J. Wegener, G. Y. Mitronova, L. ElShareif, C. Quentin, V. Belov, T. Pochechueva, G. Hasenfuss, L. Ackermann, and S. E. Lehnart, “A dual-targeted drug inhibits cardiac ryanodine receptor Ca2+ leak but activates SERCA2a Ca uptake”, Life Science Alliance, 2023, 7, : e202302278.
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  • [50]
    2023 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2984660 OA
    G. Y. Mitronova, C. Quentin, V. N. Belov, J. Wegener, K. A. Kiszka, and S. E. Lehnart, “1,4-Benzothiazepines with Cyclopropanol Groups and Their Structural Analogues Exhibit Both RyR2-Stabilizing and SERCA2a-Stimulating Activities”, Journal of Medicinal Chemistry, 2023.
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  • [49]
    2022 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984472 OA
    S. Brandenburg, J. Pawlowitz, V. Steckmeister, H. Subramanian, D. Uhlenkamp, M. Scardigli, M. Mushtaq, S. I. Amlaz, T. Kohl, J. Wegener, et al., “A junctional cAMP compartment regulates rapid Ca2+ signaling in atrial myocytes”, Journal of Molecular and Cellular Cardiology, 2022, 165, 141-157.
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  • [48]
    2022 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984471
    F. Vandewiele, A. Pironet, G. Jacobs, M. Kecskés, J. Wegener, S. Kerselaers, L. Hendrikx, J. Verelst, K. Philippaert, W. Oosterlinck, et al., “TRPM4 inhibition by meclofenamate suppresses Ca2+-dependent triggered arrhythmias”, European Heart Journal, 2022, 43, 4195-4207.
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  • [47]
    2021 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984475
    J. Peper, D. Kownatzki-Danger, G. Weninger, F. Seibertz, J. R. D. Pronto, H. Sutanto, D. Pacheu-Grau, R. Hindmarsh, S. Brandenburg, T. Kohl, et al., “Caveolin3 Stabilizes McT1-Mediated Lactate/Proton Transport in Cardiomyocytes”, Circulation Research, 2021, 128.
    PUB | DOI
     
  • [46]
    2021 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984474
    F. Berisha, K. R. Götz, J. Wegener, S. Brandenburg, H. Subramanian, C. E. Molina, A. Rüffer, J. Petersen, A. Bernhardt, E. Girdauskas, et al., “cAMP Imaging at Ryanodine Receptors Reveals β -Adrenoceptor Driven Arrhythmias”, Circulation Research, 2021, 129, 81-94.
    PUB | DOI
     
  • [45]
    2021 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984473
    J. Wegener, A. Wagdi, E. Wagner, D. M. Katschinski, G. Hasenfuss, T. Bruegmann, and S. E. Lehnart, “The RyR2-R2474S Mutation Sensitizes Cardiomyocytes and Hearts to Catecholaminergic Stress-Induced Oxidation of the Mitochondrial Glutathione Pool”, Frontiers in Physiology, 2021, 12.
    PUB | DOI
     
  • [44]
    2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984476
    K. Domes, E. Patrucco, F. Loga, A. Dietrich, L. Birnbaumer, J. Wegener, and F. Hofmann, “Murine cardiac growth, TRPC channels, and cGMP kinase I”, Pflügers Archiv - European Journal of Physiology, 2015, 467, 2229-2234.
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  • [43]
    2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2684327
    A. B. Dongmo, P. A. Nkeng-Efouet, K. P. Devkota, J. Wegener, N. Sewald, H. Wagner, and W. Vierling, “Tetra-acetylajugasterone a new constituent of Vitex cienkowskii with vasorelaxant activity”, Phytomedicine, 2014, 21, 787-792.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [42]
    2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984477
    F. Hofmann, V. Flockerzi, S. Kahl, and J. Wegener, “L-Type Ca 1.2 Calcium Channels: From In Vitro Findings to In Vivo Function”, Physiological Reviews, 2014, 94, 303-326.
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  • [41]
    2013 | Sammelwerksbeitrag | Veröffentlicht | PUB-ID: 2984481
    F. Hofmann, and J. Wegener, in Guanylate Cyclase and Cyclic GMP. Methods and Protocols (Eds.: T. Krieg, R. Lukowski), Humana Press, Totowa, NJ, 2013, p. 17-50.
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  • [40]
    2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984480
    J. Ding, K. Domes, F. Hofmann, and J. Wegener, “Truncation of murine CaV1.2 at Asp 1904 increases CaV1.3 expression in embryonic atrial cardiomyocytes”, Pflügers Archiv - European Journal of Physiology, 2013, 465, 955-964.
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  • [39]
    2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984479
    F. Loga, K. Domes, M. Freichel, V. Flockerzi, A. Dietrich, L. Birnbaumer, F. Hofmann, and J. Wegener, “The role of cGMP/cGKI signalling and Trpc channels in regulation of vascular tone”, Cardiovascular Research, 2013, 100, 280-287.
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  • [38]
    2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984478
    J. Wegener, F. Loga, D. Stegner, B. Nieswandt, and F. Hofmann, “Phospholipase D1 is involved in α‐adrenergic contraction of murine vascular smooth muscle”, The FASEB Journal, 2013, 28, 1044-1048.
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  • [37]
    2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984483 OA
    A. Blaich, S. Pahlavan, Q. Tian, M. Oberhofer, M. Poomvanicha, P. Lenhardt, K. Domes, J. Wegener, S. Moosmang, S. Ruppenthal, et al., “Mutation of the Calmodulin Binding Motif IQ of the L-type Cav1.2 Ca2+ Channel to EQ Induces Dilated Cardiomyopathy and Death”, Journal of Biological Chemistry, 2012, 287, 22616-22625.
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  • [36]
    2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984482 OA
    J. Brandmayr, M. Poomvanicha, K. Domes, J. Ding, A. Blaich, J. Wegener, S. Moosmang, and F. Hofmann, “Deletion of the C-terminal Phosphorylation Sites in the Cardiac β-Subunit Does Not Affect the Basic β-Adrenergic Response of the Heart and the Cav1.2 Channel”, Journal of Biological Chemistry, 2012, 287, 22584-22592.
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  • [35]
    2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984487 OA
    M. Poomvanicha, J. Wegener, A. Blaich, S. Fischer, K. Domes, S. Moosmang, and F. Hofmann, “Facilitation and Ca2+-dependent Inactivation Are Modified by Mutation of the Cav1.2 Channel IQ Motif”, Journal of Biological Chemistry, 2011, 286, 26702-26707.
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  • [34]
    2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984486 OA
    K. Domes, J. Ding, T. Lemke, A. Blaich, J. Wegener, J. Brandmayr, S. Moosmang, and F. Hofmann, “Truncation of Murine Cav1.2 at Asp-1904 Results in Heart Failure after Birth”, Journal of Biological Chemistry, 2011, 286, 33863-33871.
    PUB | PDF | DOI | Download (ext.)
     
  • [33]
    2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984485
    C. Ertl, R. Lukowski, K. Sigl, J. Schlossmann, F. Hofmann, and J. Wegener, “Kinetics of relaxation by cGMP/cGKI signaling in fundus smooth muscle”, European Journal of Pharmacology, 2011, 670, 266-271.
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  • [32]
    2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984484
    A. K. Singh, B. Spieβberger, W. Zheng, F. Xiao, R. Lukowski, J. Wegener, P. Weinmeister, D. Saur, S. Klein, M. Schemann, et al., “Neuronal cGMP kinase I is essential for stimulation of duodenal bicarbonate secretion by luminal acid”, The FASEB Journal, 2011, 26, 1745-1754.
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  • [31]
    2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984489
    M. Desch, K. Sigl, B. Hieke, K. Salb, F. Kees, D. Bernhard, A. Jochim, B. Spiessberger, K. Höcherl, R. Feil, et al., “IRAG determines nitric oxide- and atrial natriuretic peptide-mediated smooth muscle relaxation”, Cardiovascular Research, 2010, 86, 496-505.
    PUB | DOI
     
  • [30]
    2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984488
    M. Huster, E. Frei, F. Hofmann, and J. Wegener, “A complex of Ca 1.2/PKC is involved in muscarinic signaling in smooth muscle”, The FASEB Journal, 2010, 24, 2651-2659.
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  • [29]
    2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2985980
    E. Frei, M. Huster, P. Smital, J. Schlossmann, F. Hofmann, and J. Wegener, “Calcium-dependent and calcium-independent inhibition of contraction by cGMP/cGKI in intestinal smooth muscle”, American Journal of Physiology-Gastrointestinal and Liver Physiology, 2009, 297, G834-G839.
    PUB | DOI
     
  • [28]
    2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984490
    E. Frei, F. Hofmann, and J. Wegener, “Phospholipase C mediated Ca2+ signals in murine urinary bladder smooth muscle”, European Journal of Pharmacology, 2009, 610, 106-109.
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  • [27]
    2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984494
    R. Wörner, R. Lukowski, F. Hofmann, and J. Wegener, “cGMP signals mainly through cAMP kinase in permeabilized murine aorta”, American Journal of Physiology-Heart and Circulatory Physiology, 2007, 292, H237-H244.
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  • [26]
    2007 | Sammelwerksbeitrag | Veröffentlicht | PUB-ID: 2984493
    S. Moosmang, T. Kleppisch, J. Wegener, A. Welling, and F. Hofmann, in Conditional Mutagenesis: An Approach to Disease Models (Eds.: R. Feil, D. Metzger), Springer Berlin Heidelberg, Berlin, Heidelberg, 2007, p. 469-490.
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  • [25]
    2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984492
    M. Angstenberger, J. Wegener, B. J. Pichler, M. S. Judenhofer, S. Feil, S. Alberti, R. Feil, and A. Nordheim, “Severe Intestinal Obstruction on Induced Smooth Muscle–Specific Ablation of the Transcription Factor SRF in Adult Mice”, Gastroenterology, 2007, 133, 1948-1959.
    PUB | DOI
     
  • [24]
    2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984491
    S. Weber, D. Bernhard, R. Lukowski, P. Weinmeister, R. Wörner, J. Wegener, N. Valtcheva, S. Feil, J. Schlossmann, F. Hofmann, et al., “Rescue of cGMP Kinase I Knockout Mice by Smooth Muscle–Specific Expression of Either Isozyme”, Circulation Research, 2007, 101, 1096-1103.
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  • [23]
    2006 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984495
    J. Wegener, V. Schulla, A. Koller, N. Klugbauer, R. Feil, F. Hofmann, J. W. Wegener, V. Schulla, A. Koller, N. Klugbauer, et al., “Control of intestinal motility by the Ca 1.2 L‐type calcium channel in mice”, The FASEB Journal, 2006, 20, 1260-1262.
    PUB | DOI
     
  • [22]
    2005 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984496
    A. Welling, F. Hofmann, and J. Wegener, “Inhibition of L-Type Ca 1.2 Ca Channels by 2,(4-Morpholinyl)-8-phenyl-4 -1-benzopyran-4-one (LY294002) and 2-[1-(3-Dimethyl-aminopropyl)-5-methoxyindol-3-yl]-3-(1 -indol-3-yl) Maleimide (Gö6983)”, Molecular Pharmacology, 2005, 67, 541-544.
    PUB | DOI
     
  • [21]
    2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984498
    J. Wegener, V. Schulla, T. ‐S. Lee, A. Koller, S. Feil, R. Feil, T. Kleppisch, N. Klugbauer, S. Moosmang, A. Welling, et al., “An essential role of Ca 1.2 L‐type calcium channel for urinary bladder function”, The FASEB Journal, 2004, 18, 1159-1161.
    PUB | DOI
     
  • [20]
    2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984497
    A. Geiselhöringer, M. Werner, K. Sigl, P. Smital, R. Wörner, L. Acheo, J. Stieber, P. Weinmeister, R. Feil, S. Feil, et al., “IRAG is essential for relaxation of receptor-triggered smooth muscle contraction by cGMP kinase”, The EMBO Journal, 2004, 23, 4222-4231.
    PUB | DOI
     
  • [19]
    2003 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984501
    J. Wegener, C. Korstanje, and H. Nawrath, “Voltage-Dependent Effects of Barnidipine in Rat Vascular Smooth Muscle”, Journal of Cardiovascular Pharmacology, 2003, 42, 218-223.
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  • [18]
    2003 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984500
    J. Wegener, M. Lee, and F. Hofmann, “Hypothyroidism does not affect the dihydropyridine sensitivity of precontracted murine uterus”, Canadian Journal of Physiology and Pharmacology, 2003, 81, 890-893.
    PUB | DOI
     
  • [17]
    2003 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984499
    S. Moosmang, V. Schulla, A. Welling, R. Feil, S. Feil, J. Wegener, F. Hofmann, and N. Klugbauer, “Dominant role of smooth muscle L-type calcium channel Cav1.2 for blood pressure regulation”, The EMBO Journal, 2003, 22, 6027-6034.
    PUB | DOI
     
  • [16]
    2002 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984503
    J. Wegener, H. Nawrath, W. Wolfsgruber, S. Kühbandner, C. Werner, F. Hofmann, and R. Feil, “cGMP-Dependent Protein Kinase I Mediates the Negative Inotropic Effect of cGMP in the Murine Myocardium”, Circulation Research, 2002, 90, 18-20.
    PUB | DOI
     
  • [15]
    2002 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984502
    D. Michel, J. Wegener, and H. Nawrath, “Effects of Quinine and Quinidine on the Transient Outward and on the L-Type Ca<sup>2+</sup> Current in Rat Ventricular Cardiomyocytes”, Pharmacology, 2002, 65, 187-192.
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  • [14]
    2001 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984504
    C. E. Budu, N. Balas, H. Nawrath, J. Wegener, and A. Shainberg, “Increased Cardiac Alpha-1-Adrenoceptor Density in Rats Following Treatment with Amiodarone”, Journal of Basic and Clinical Physiology and Pharmacology, 2001, 12, 33-48.
    PUB | DOI
     
  • [13]
    2000 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984506
    S. D. Vulcu, J. Wegener, and H. Nawrath, “Differences in the nitric oxide/soluble guanylyl cyclase signalling pathway in the myocardium of neonatal and adult rats”, European Journal of Pharmacology, 2000, 406, 247-255.
    PUB | DOI
     
  • [12]
    2000 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984505
    H. Nawrath, J. Wegener, J. Rupp, A. Habermeier, and E. I. Closs, “Voltage dependence of -arginine transport by hCAT-2A and hCAT-2B expressed in oocytes from”, American Journal of Physiology-Cell Physiology, 2000, 279, C1336-C1344.
    PUB | DOI
     
  • [11]
    1999 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984508
    V. Fassbender, J. Wegener, A. Shainberg, and H. Nawrath, “Inhibition by Fendiline of the Transient Outward Current in Rat Ventricular Cardiomyocytes”, Journal of Cardiovascular Pharmacology, 1999, 33, 905-911.
    PUB | DOI
     
  • [10]
    1999 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984507
    S. Seitz, J. Wegener, J. Rupp, M. Watanabe, A. Jost, R. Gerhard, A. Shainberg, R. Ochi, and H. Nawrath, “Involvement of K+ channels in the relaxant effects of YC-1 in vascular smooth muscle”, European Journal of Pharmacology, 1999, 382, 11-18.
    PUB | DOI
     
  • [9]
    1997 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984511
    J. Wegener, and H. Nawrath, “Differential effects of isoliquiritigenin and YC-1 in rat aortic smooth muscle”, European Journal of Pharmacology, 1997, 323, 89-91.
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  • [8]
    1997 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984510
    J. Wegener, and H. Nawrath, “Cardiac effects of isoliquiritigenin”, European Journal of Pharmacology, 1997, 326, 37-44.
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  • [7]
    1997 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984509
    J. Wegener, W. Hanke, and H. Breer, “Second messenger-controlled membrane conductance in locust (Locusta migratoria) olfactory neurons”, Journal of Insect Physiology, 1997, 43, 595-603.
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  • [6]
    1996 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984513
    J. Wegener, and H. Nawrath, “Action of tertiary phenylalkylamines on cardiac transient outward current from outside the cell membrane”, Naunyn-Schmiedeberg's Archives of Pharmacology, 1996, 354, 746-754.
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  • [5]
    1996 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984512
    H. Nawrath, and J. Wegener, “Kinetics and state-dependent effects of verapamil on cardiac L-type calcium channels”, Naunyn-Schmiedeberg's Archives of Pharmacology, 1996, 355, 79-86.
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  • [4]
    1995 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984515
    J. Wegener, and H. Nawrath, “Extracellular site of action of phenylalkylamines on L-type calcium current in rat ventricular myocytes”, Naunyn-Schmiedeberg's Archives of Pharmacology, 1995, 352.
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  • [3]
    1995 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984514
    J. Wegener, and H. Nawrath, “Alkalinisation does not modify the effect of verapamil on myocardial Ca2+ current”, European Journal of Pharmacology, 1995, 287, 89-92.
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  • [2]
    1993 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984640
    J. Wegener, I. Boekhoff, E. Tareilus, and H. Breer, “Olfactory signalling in antennal receptor neurones of the locust (Locusta migratoria)”, Journal of Insect Physiology, 1993, 39, 153-163.
    PUB | DOI | Download (ext.)
     
  • [1]
    1992 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984636
    J. Wegener, E. Tareilus, and H. Breer, “Characterization of calcium-dependent potassium channels in antennal receptor neurones of Locusta migratoria”, Journal of Insect Physiology, 1992, 38, 237-248.
    PUB | DOI
     
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