52 Publikationen
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2024 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2986115Rapöhn, Marcel, Cyganek, Lukas, Voigt, Niels, Hasenfuß, Gerd, Lehnart, Stephan E., and Wegener, Jörg. 2024. “Non-invasive analysis of contractility during identical maturations revealed two phenotypes in ventricular but not in atrial iPSC-CM”. American Journal of Physiology-Heart and Circulatory Physiology, 35.
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2023 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984773Wegener, Jörg, Mitronova, Gyuzel Y, ElShareif, Lina, Quentin, Christine, Belov, Vladimir, Pochechueva, Tatiana, Hasenfuss, Gerd, Ackermann, Lutz, and Lehnart, Stephan E. 2023. “A dual-targeted drug inhibits cardiac ryanodine receptor Ca2+ leak but activates SERCA2a Ca uptake”. Life Science Alliance 7 (2): e202302278.
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2023 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2984660Mitronova, Gyuzel Y., Quentin, Christine, Belov, Vladimir N., Wegener, Jörg, Kiszka, Kamila A., and Lehnart, Stephan E. 2023. “1,4-Benzothiazepines with Cyclopropanol Groups and Their Structural Analogues Exhibit Both RyR2-Stabilizing and SERCA2a-Stimulating Activities”. Journal of Medicinal Chemistry.
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2022 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984472Brandenburg, Sören, Pawlowitz, Jan, Steckmeister, Vanessa, Subramanian, Hariharan, Uhlenkamp, Dennis, Scardigli, Marina, Mushtaq, Mufassra, et al. 2022. “A junctional cAMP compartment regulates rapid Ca2+ signaling in atrial myocytes”. Journal of Molecular and Cellular Cardiology 165: 141-157.
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2022 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984471Vandewiele, Frone, Pironet, Andy, Jacobs, Griet, Kecskés, Miklos, Wegener, Jörg, Kerselaers, Sara, Hendrikx, Lio, et al. 2022. “TRPM4 inhibition by meclofenamate suppresses Ca2+-dependent triggered arrhythmias”. European Heart Journal 43 (40): 4195-4207.
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2021 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984475Peper, Jonas, Kownatzki-Danger, Daniel, Weninger, Gunnar, Seibertz, Fitzwilliam, Pronto, Julius Ryan D., Sutanto, Henry, Pacheu-Grau, David, et al. 2021. “Caveolin3 Stabilizes McT1-Mediated Lactate/Proton Transport in Cardiomyocytes”. Circulation Research 128 (6).
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2021 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984474Berisha, Filip, Götz, Konrad R., Wegener, Jörg, Brandenburg, Sören, Subramanian, Hariharan, Molina, Cristina E., Rüffer, André, et al. 2021. “cAMP Imaging at Ryanodine Receptors Reveals β -Adrenoceptor Driven Arrhythmias”. Circulation Research 129 (1): 81-94.
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2021 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984473Wegener, Jörg, Wagdi, Ahmed, Wagner, Eva, Katschinski, Dörthe M., Hasenfuss, Gerd, Bruegmann, Tobias, and Lehnart, Stephan E. 2021. “The RyR2-R2474S Mutation Sensitizes Cardiomyocytes and Hearts to Catecholaminergic Stress-Induced Oxidation of the Mitochondrial Glutathione Pool”. Frontiers in Physiology 12.
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2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984476Domes, Katrin, Patrucco, Enrico, Loga, Florian, Dietrich, Alexander, Birnbaumer, Lutz, Wegener, Jörg, and Hofmann, Franz. 2015. “Murine cardiac growth, TRPC channels, and cGMP kinase I”. Pflügers Archiv - European Journal of Physiology 467 (10): 2229-2234.
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2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2684327Dongmo, Alain Bertrand, Nkeng-Efouet, Pepin Alango, Devkota, Krishna Prasad, Wegener, Jörg, Sewald, Norbert, Wagner, Hildebert, and Vierling, Wolfgang. 2014. “Tetra-acetylajugasterone a new constituent of Vitex cienkowskii with vasorelaxant activity”. Phytomedicine 21 (6): 787-792.
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2013 | Sammelwerksbeitrag | Veröffentlicht | PUB-ID: 2984481Hofmann, Franz, and Wegener, Jörg. 2013. “cGMP-Dependent Protein Kinases (cGK)”. In Guanylate Cyclase and Cyclic GMP. Methods and Protocols, ed. Thomas Krieg and Robert Lukowski, 17-50. Methods in Molecular Biology. Totowa, NJ: Humana Press.
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2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984480Ding, Jie, Domes, Katrin, Hofmann, Franz, and Wegener, Jörg. 2013. “Truncation of murine CaV1.2 at Asp 1904 increases CaV1.3 expression in embryonic atrial cardiomyocytes”. Pflügers Archiv - European Journal of Physiology 465 (7): 955-964.
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2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984479Loga, Florian, Domes, Katrin, Freichel, Marc, Flockerzi, Veit, Dietrich, Alexander, Birnbaumer, Lutz, Hofmann, Franz, and Wegener, Jörg. 2013. “The role of cGMP/cGKI signalling and Trpc channels in regulation of vascular tone”. Cardiovascular Research 100 (2): 280-287.
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2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984483Blaich, Anne, Pahlavan, Sara, Tian, Qinghai, Oberhofer, Martin, Poomvanicha, Montatip, Lenhardt, Peter, Domes, Katrin, et al. 2012. “Mutation of the Calmodulin Binding Motif IQ of the L-type Cav1.2 Ca2+ Channel to EQ Induces Dilated Cardiomyopathy and Death”. Journal of Biological Chemistry 287 (27): 22616-22625.
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2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984482Brandmayr, Julia, Poomvanicha, Montatip, Domes, Katrin, Ding, Jie, Blaich, Anne, Wegener, Jörg, Moosmang, Sven, and Hofmann, Franz. 2012. “Deletion of the C-terminal Phosphorylation Sites in the Cardiac β-Subunit Does Not Affect the Basic β-Adrenergic Response of the Heart and the Cav1.2 Channel”. Journal of Biological Chemistry 287 (27): 22584-22592.
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2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984487Poomvanicha, Montatip, Wegener, Jörg, Blaich, Anne, Fischer, Stefanie, Domes, Katrin, Moosmang, Sven, and Hofmann, Franz. 2011. “Facilitation and Ca2+-dependent Inactivation Are Modified by Mutation of the Cav1.2 Channel IQ Motif”. Journal of Biological Chemistry 286 (30): 26702-26707.
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2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984486Domes, Katrin, Ding, Jie, Lemke, Toni, Blaich, Anne, Wegener, Jörg, Brandmayr, Julia, Moosmang, Sven, and Hofmann, Franz. 2011. “Truncation of Murine Cav1.2 at Asp-1904 Results in Heart Failure after Birth”. Journal of Biological Chemistry 286 (39): 33863-33871.
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2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984485Ertl, Claudia, Lukowski, Robert, Sigl, Katja, Schlossmann, Jens, Hofmann, Franz, and Wegener, Jörg. 2011. “Kinetics of relaxation by cGMP/cGKI signaling in fundus smooth muscle”. European Journal of Pharmacology 670 (1): 266-271.
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2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984484Singh, Anurag Kumar, Spieβberger, Beate, Zheng, Wen, Xiao, Fang, Lukowski, Robert, Wegener, Jörg, Weinmeister, Pascal, et al. 2011. “Neuronal cGMP kinase I is essential for stimulation of duodenal bicarbonate secretion by luminal acid”. The FASEB Journal 26 (4): 1745-1754.
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2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984489Desch, Matthias, Sigl, Katja, Hieke, Bernhard, Salb, Katharina, Kees, Frieder, Bernhard, Dominik, Jochim, Angela, et al. 2010. “IRAG determines nitric oxide- and atrial natriuretic peptide-mediated smooth muscle relaxation”. Cardiovascular Research 86 (3): 496-505.
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2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2985980Frei, Eva, Huster, Maria, Smital, Petra, Schlossmann, Jens, Hofmann, Franz, and Wegener, Jörg. 2009. “Calcium-dependent and calcium-independent inhibition of contraction by cGMP/cGKI in intestinal smooth muscle”. American Journal of Physiology-Gastrointestinal and Liver Physiology 297 (4): G834-G839.
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2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984494Wörner, René, Lukowski, Robert, Hofmann, Franz, and Wegener, Jörg. 2007. “cGMP signals mainly through cAMP kinase in permeabilized murine aorta”. American Journal of Physiology-Heart and Circulatory Physiology 292 (1): H237-H244.
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2007 | Sammelwerksbeitrag | Veröffentlicht | PUB-ID: 2984493Moosmang, S., Kleppisch, T., Wegener, Jörg, Welling, A., and Hofmann, F. 2007. “Analysis of Calcium Channels by Conditional Mutagenesis”. In Conditional Mutagenesis: An Approach to Disease Models, ed. Robert Feil and Daniel Metzger, 469-490. Handbook of Experimental Pharmacology. Berlin, Heidelberg: Springer Berlin Heidelberg.
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2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984492Angstenberger, Meike, Wegener, Jörg, Pichler, Bernd J., Judenhofer, Martin S., Feil, Susanne, Alberti, Siegfried, Feil, Robert, and Nordheim, Alfred. 2007. “Severe Intestinal Obstruction on Induced Smooth Muscle–Specific Ablation of the Transcription Factor SRF in Adult Mice”. Gastroenterology 133 (6): 1948-1959.
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2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984491Weber, Silke, Bernhard, Dominik, Lukowski, Robert, Weinmeister, Pascal, Wörner, René, Wegener, Jörg, Valtcheva, Nadejda, et al. 2007. “Rescue of cGMP Kinase I Knockout Mice by Smooth Muscle–Specific Expression of Either Isozyme”. Circulation Research 101 (11): 1096-1103.
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2006 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984495Wegener, Jörg, Schulla, Verena, Koller, Angela, Klugbauer, Norbert, Feil, Robert, Hofmann, Franz, Wegener, Jörg W., et al. 2006. “Control of intestinal motility by the Ca 1.2 L‐type calcium channel in mice”. The FASEB Journal 20 (8): 1260-1262.
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2005 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984496Welling, A., Hofmann, F., and Wegener, Jörg. 2005. “Inhibition of L-Type Ca 1.2 Ca Channels by 2,(4-Morpholinyl)-8-phenyl-4 -1-benzopyran-4-one (LY294002) and 2-[1-(3-Dimethyl-aminopropyl)-5-methoxyindol-3-yl]-3-(1 -indol-3-yl) Maleimide (Gö6983)”. Molecular Pharmacology 67 (2): 541-544.
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2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984498Wegener, Jörg, Schulla, Verena, Lee, Tae‐Seong, Koller, Angela, Feil, Susanne, Feil, Robert, Kleppisch, Thomas, et al. 2004. “An essential role of Ca 1.2 L‐type calcium channel for urinary bladder function”. The FASEB Journal 18 (10): 1159-1161.
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2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984497Geiselhöringer, Angela, Werner, Matthias, Sigl, Katja, Smital, Petra, Wörner, René, Acheo, Linda, Stieber, Juliane, et al. 2004. “IRAG is essential for relaxation of receptor-triggered smooth muscle contraction by cGMP kinase”. The EMBO Journal 23 (21): 4222-4231.
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2003 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984499Moosmang, Sven, Schulla, Verena, Welling, Andrea, Feil, Robert, Feil, Susanne, Wegener, Jörg, Hofmann, Franz, and Klugbauer, Norbert. 2003. “Dominant role of smooth muscle L-type calcium channel Cav1.2 for blood pressure regulation”. The EMBO Journal 22 (22): 6027-6034.
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2002 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984503Wegener, Jörg, Nawrath, Hermann, Wolfsgruber, Wiebke, Kühbandner, Susanne, Werner, Claudia, Hofmann, Franz, and Feil, Robert. 2002. “cGMP-Dependent Protein Kinase I Mediates the Negative Inotropic Effect of cGMP in the Murine Myocardium”. Circulation Research 90 (1): 18-20.
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2001 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984504Budu, C.E., Balas, N., Nawrath, H., Wegener, Jörg, and Shainberg, A. 2001. “Increased Cardiac Alpha-1-Adrenoceptor Density in Rats Following Treatment with Amiodarone”. Journal of Basic and Clinical Physiology and Pharmacology 12 (1): 33-48.
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2000 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984506Vulcu, Sebastian D., Wegener, Jörg, and Nawrath, Hermann. 2000. “Differences in the nitric oxide/soluble guanylyl cyclase signalling pathway in the myocardium of neonatal and adult rats”. European Journal of Pharmacology 406 (2): 247-255.
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2000 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984505Nawrath, Hermann, Wegener, Jörg, Rupp, Johanna, Habermeier, Alice, and Closs, Ellen I. 2000. “Voltage dependence of -arginine transport by hCAT-2A and hCAT-2B expressed in oocytes from”. American Journal of Physiology-Cell Physiology 279 (5): C1336-C1344.
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1999 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984508Fassbender, Verena, Wegener, Jörg, Shainberg, Asher, and Nawrath, Hermann. 1999. “Inhibition by Fendiline of the Transient Outward Current in Rat Ventricular Cardiomyocytes”. Journal of Cardiovascular Pharmacology 33 (6): 905-911.
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1999 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984507Seitz, Sabine, Wegener, Jörg, Rupp, Johanna, Watanabe, Makino, Jost, Andreas, Gerhard, Rolf, Shainberg, Asher, Ochi, Rikuo, and Nawrath, Hermann. 1999. “Involvement of K+ channels in the relaxant effects of YC-1 in vascular smooth muscle”. European Journal of Pharmacology 382 (1): 11-18.
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1993 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984640Wegener, Jörg, Boekhoff, I., Tareilus, E., and Breer, H. 1993. “Olfactory signalling in antennal receptor neurones of the locust (Locusta migratoria)”. Journal of Insect Physiology 39 (2): 153-163.
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