52 Publikationen

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  • [52]
    2024 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2986115
    Rapöhn M, Cyganek L, Voigt N, Hasenfuß G, Lehnart SE, Wegener J. Non-invasive analysis of contractility during identical maturations revealed two phenotypes in ventricular but not in atrial iPSC-CM. American Journal of Physiology-Heart and Circulatory Physiology. 2024:35.
    PUB | DOI
     
  • [51]
    2023 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984773 OA
    Wegener J, Mitronova GY, ElShareif L, et al. A dual-targeted drug inhibits cardiac ryanodine receptor Ca2+ leak but activates SERCA2a Ca uptake. Life Science Alliance. 2023;7(2): e202302278.
    PUB | PDF | DOI | Download (ext.)
     
  • [50]
    2023 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2984660 OA
    Mitronova GY, Quentin C, Belov VN, Wegener J, Kiszka KA, Lehnart SE. 1,4-Benzothiazepines with Cyclopropanol Groups and Their Structural Analogues Exhibit Both RyR2-Stabilizing and SERCA2a-Stimulating Activities. Journal of Medicinal Chemistry. 2023.
    PUB | PDF | DOI
     
  • [49]
    2022 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984472 OA
    Brandenburg S, Pawlowitz J, Steckmeister V, et al. A junctional cAMP compartment regulates rapid Ca2+ signaling in atrial myocytes. Journal of Molecular and Cellular Cardiology. 2022;165:141-157.
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  • [48]
    2022 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984471
    Vandewiele F, Pironet A, Jacobs G, et al. TRPM4 inhibition by meclofenamate suppresses Ca2+-dependent triggered arrhythmias. European Heart Journal. 2022;43(40):4195-4207.
    PUB | DOI
     
  • [47]
    2021 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984475
    Peper J, Kownatzki-Danger D, Weninger G, et al. Caveolin3 Stabilizes McT1-Mediated Lactate/Proton Transport in Cardiomyocytes. Circulation Research. 2021;128(6).
    PUB | DOI
     
  • [46]
    2021 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984474
    Berisha F, Götz KR, Wegener J, et al. cAMP Imaging at Ryanodine Receptors Reveals β -Adrenoceptor Driven Arrhythmias. Circulation Research. 2021;129(1):81-94.
    PUB | DOI
     
  • [45]
    2021 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984473
    Wegener J, Wagdi A, Wagner E, et al. The RyR2-R2474S Mutation Sensitizes Cardiomyocytes and Hearts to Catecholaminergic Stress-Induced Oxidation of the Mitochondrial Glutathione Pool. Frontiers in Physiology. 2021;12.
    PUB | DOI
     
  • [44]
    2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984476
    Domes K, Patrucco E, Loga F, et al. Murine cardiac growth, TRPC channels, and cGMP kinase I. Pflügers Archiv - European Journal of Physiology. 2015;467(10):2229-2234.
    PUB | DOI
     
  • [43]
    2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2684327
    Dongmo AB, Nkeng-Efouet PA, Devkota KP, et al. Tetra-acetylajugasterone a new constituent of Vitex cienkowskii with vasorelaxant activity. Phytomedicine. 2014;21(6):787-792.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [42]
    2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984477
    Hofmann F, Flockerzi V, Kahl S, Wegener J. L-Type Ca 1.2 Calcium Channels: From In Vitro Findings to In Vivo Function. Physiological Reviews. 2014;94(1):303-326.
    PUB | DOI
     
  • [41]
    2013 | Sammelwerksbeitrag | Veröffentlicht | PUB-ID: 2984481
    Hofmann F, Wegener J. cGMP-Dependent Protein Kinases (cGK). In: Krieg T, Lukowski R, eds. Guanylate Cyclase and Cyclic GMP. Methods and Protocols. Methods in Molecular Biology. Totowa, NJ: Humana Press; 2013: 17-50.
    PUB | DOI
     
  • [40]
    2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984480
    Ding J, Domes K, Hofmann F, Wegener J. Truncation of murine CaV1.2 at Asp 1904 increases CaV1.3 expression in embryonic atrial cardiomyocytes. Pflügers Archiv - European Journal of Physiology. 2013;465(7):955-964.
    PUB | DOI
     
  • [39]
    2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984479
    Loga F, Domes K, Freichel M, et al. The role of cGMP/cGKI signalling and Trpc channels in regulation of vascular tone. Cardiovascular Research. 2013;100(2):280-287.
    PUB | DOI
     
  • [38]
    2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984478
    Wegener J, Loga F, Stegner D, Nieswandt B, Hofmann F. Phospholipase D1 is involved in α‐adrenergic contraction of murine vascular smooth muscle. The FASEB Journal. 2013;28(3):1044-1048.
    PUB | DOI
     
  • [37]
    2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984483 OA
    Blaich A, Pahlavan S, Tian Q, et al. Mutation of the Calmodulin Binding Motif IQ of the L-type Cav1.2 Ca2+ Channel to EQ Induces Dilated Cardiomyopathy and Death. Journal of Biological Chemistry. 2012;287(27):22616-22625.
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  • [36]
    2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984482 OA
    Brandmayr J, Poomvanicha M, Domes K, et al. Deletion of the C-terminal Phosphorylation Sites in the Cardiac β-Subunit Does Not Affect the Basic β-Adrenergic Response of the Heart and the Cav1.2 Channel. Journal of Biological Chemistry. 2012;287(27):22584-22592.
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  • [35]
    2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984487 OA
    Poomvanicha M, Wegener J, Blaich A, et al. Facilitation and Ca2+-dependent Inactivation Are Modified by Mutation of the Cav1.2 Channel IQ Motif. Journal of Biological Chemistry. 2011;286(30):26702-26707.
    PUB | PDF | DOI | Download (ext.)
     
  • [34]
    2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984486 OA
    Domes K, Ding J, Lemke T, et al. Truncation of Murine Cav1.2 at Asp-1904 Results in Heart Failure after Birth. Journal of Biological Chemistry. 2011;286(39):33863-33871.
    PUB | PDF | DOI | Download (ext.)
     
  • [33]
    2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984485
    Ertl C, Lukowski R, Sigl K, Schlossmann J, Hofmann F, Wegener J. Kinetics of relaxation by cGMP/cGKI signaling in fundus smooth muscle. European Journal of Pharmacology. 2011;670(1):266-271.
    PUB | DOI
     
  • [32]
    2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984484
    Singh AK, Spieβberger B, Zheng W, et al. Neuronal cGMP kinase I is essential for stimulation of duodenal bicarbonate secretion by luminal acid. The FASEB Journal. 2011;26(4):1745-1754.
    PUB | DOI
     
  • [31]
    2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984489
    Desch M, Sigl K, Hieke B, et al. IRAG determines nitric oxide- and atrial natriuretic peptide-mediated smooth muscle relaxation. Cardiovascular Research. 2010;86(3):496-505.
    PUB | DOI
     
  • [30]
    2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984488
    Huster M, Frei E, Hofmann F, Wegener J. A complex of Ca 1.2/PKC is involved in muscarinic signaling in smooth muscle. The FASEB Journal. 2010;24(8):2651-2659.
    PUB | DOI
     
  • [29]
    2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2985980
    Frei E, Huster M, Smital P, Schlossmann J, Hofmann F, Wegener J. Calcium-dependent and calcium-independent inhibition of contraction by cGMP/cGKI in intestinal smooth muscle. American Journal of Physiology-Gastrointestinal and Liver Physiology. 2009;297(4):G834-G839.
    PUB | DOI
     
  • [28]
    2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984490
    Frei E, Hofmann F, Wegener J. Phospholipase C mediated Ca2+ signals in murine urinary bladder smooth muscle. European Journal of Pharmacology. 2009;610(1-3):106-109.
    PUB | DOI
     
  • [27]
    2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984494
    Wörner R, Lukowski R, Hofmann F, Wegener J. cGMP signals mainly through cAMP kinase in permeabilized murine aorta. American Journal of Physiology-Heart and Circulatory Physiology. 2007;292(1):H237-H244.
    PUB | DOI
     
  • [26]
    2007 | Sammelwerksbeitrag | Veröffentlicht | PUB-ID: 2984493
    Moosmang S, Kleppisch T, Wegener J, Welling A, Hofmann F. Analysis of Calcium Channels by Conditional Mutagenesis. In: Feil R, Metzger D, eds. Conditional Mutagenesis: An Approach to Disease Models. Handbook of Experimental Pharmacology. Berlin, Heidelberg: Springer Berlin Heidelberg; 2007: 469-490.
    PUB | DOI
     
  • [25]
    2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984492
    Angstenberger M, Wegener J, Pichler BJ, et al. Severe Intestinal Obstruction on Induced Smooth Muscle–Specific Ablation of the Transcription Factor SRF in Adult Mice. Gastroenterology. 2007;133(6):1948-1959.
    PUB | DOI
     
  • [24]
    2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984491
    Weber S, Bernhard D, Lukowski R, et al. Rescue of cGMP Kinase I Knockout Mice by Smooth Muscle–Specific Expression of Either Isozyme. Circulation Research. 2007;101(11):1096-1103.
    PUB | DOI
     
  • [23]
    2006 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984495
    Wegener J, Schulla V, Koller A, et al. Control of intestinal motility by the Ca 1.2 L‐type calcium channel in mice. The FASEB Journal. 2006;20(8):1260-1262.
    PUB | DOI
     
  • [22]
    2005 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984496
    Welling A, Hofmann F, Wegener J. Inhibition of L-Type Ca 1.2 Ca Channels by 2,(4-Morpholinyl)-8-phenyl-4 -1-benzopyran-4-one (LY294002) and 2-[1-(3-Dimethyl-aminopropyl)-5-methoxyindol-3-yl]-3-(1 -indol-3-yl) Maleimide (Gö6983). Molecular Pharmacology. 2005;67(2):541-544.
    PUB | DOI
     
  • [21]
    2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984498
    Wegener J, Schulla V, Lee T‐S, et al. An essential role of Ca 1.2 L‐type calcium channel for urinary bladder function. The FASEB Journal. 2004;18(10):1159-1161.
    PUB | DOI
     
  • [20]
    2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984497
    Geiselhöringer A, Werner M, Sigl K, et al. IRAG is essential for relaxation of receptor-triggered smooth muscle contraction by cGMP kinase. The EMBO Journal. 2004;23(21):4222-4231.
    PUB | DOI
     
  • [19]
    2003 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984501
    Wegener J, Korstanje C, Nawrath H. Voltage-Dependent Effects of Barnidipine in Rat Vascular Smooth Muscle. Journal of Cardiovascular Pharmacology. 2003;42(2):218-223.
    PUB | DOI
     
  • [18]
    2003 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984500
    Wegener J, Lee M, Hofmann F. Hypothyroidism does not affect the dihydropyridine sensitivity of precontracted murine uterus. Canadian Journal of Physiology and Pharmacology. 2003;81(9):890-893.
    PUB | DOI
     
  • [17]
    2003 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984499
    Moosmang S, Schulla V, Welling A, et al. Dominant role of smooth muscle L-type calcium channel Cav1.2 for blood pressure regulation. The EMBO Journal. 2003;22(22):6027-6034.
    PUB | DOI
     
  • [16]
    2002 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984503
    Wegener J, Nawrath H, Wolfsgruber W, et al. cGMP-Dependent Protein Kinase I Mediates the Negative Inotropic Effect of cGMP in the Murine Myocardium. Circulation Research. 2002;90(1):18-20.
    PUB | DOI
     
  • [15]
    2002 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984502
    Michel D, Wegener J, Nawrath H. Effects of Quinine and Quinidine on the Transient Outward and on the L-Type Ca<sup>2+</sup> Current in Rat Ventricular Cardiomyocytes. Pharmacology. 2002;65(4):187-192.
    PUB | DOI
     
  • [14]
    2001 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984504
    Budu CE, Balas N, Nawrath H, Wegener J, Shainberg A. Increased Cardiac Alpha-1-Adrenoceptor Density in Rats Following Treatment with Amiodarone. Journal of Basic and Clinical Physiology and Pharmacology. 2001;12(1):33-48.
    PUB | DOI
     
  • [13]
    2000 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984506
    Vulcu SD, Wegener J, Nawrath H. Differences in the nitric oxide/soluble guanylyl cyclase signalling pathway in the myocardium of neonatal and adult rats. European Journal of Pharmacology. 2000;406(2):247-255.
    PUB | DOI
     
  • [12]
    2000 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984505
    Nawrath H, Wegener J, Rupp J, Habermeier A, Closs EI. Voltage dependence of -arginine transport by hCAT-2A and hCAT-2B expressed in oocytes from. American Journal of Physiology-Cell Physiology. 2000;279(5):C1336-C1344.
    PUB | DOI
     
  • [11]
    1999 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984508
    Fassbender V, Wegener J, Shainberg A, Nawrath H. Inhibition by Fendiline of the Transient Outward Current in Rat Ventricular Cardiomyocytes. Journal of Cardiovascular Pharmacology. 1999;33(6):905-911.
    PUB | DOI
     
  • [10]
    1999 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984507
    Seitz S, Wegener J, Rupp J, et al. Involvement of K+ channels in the relaxant effects of YC-1 in vascular smooth muscle. European Journal of Pharmacology. 1999;382(1):11-18.
    PUB | DOI
     
  • [9]
    1997 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984511
    Wegener J, Nawrath H. Differential effects of isoliquiritigenin and YC-1 in rat aortic smooth muscle. European Journal of Pharmacology. 1997;323(1):89-91.
    PUB | DOI
     
  • [8]
    1997 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984510
    Wegener J, Nawrath H. Cardiac effects of isoliquiritigenin. European Journal of Pharmacology. 1997;326(1):37-44.
    PUB | DOI
     
  • [7]
    1997 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984509
    Wegener J, Hanke W, Breer H. Second messenger-controlled membrane conductance in locust (Locusta migratoria) olfactory neurons. Journal of Insect Physiology. 1997;43(6):595-603.
    PUB | DOI
     
  • [6]
    1996 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984513
    Wegener J, Nawrath H. Action of tertiary phenylalkylamines on cardiac transient outward current from outside the cell membrane. Naunyn-Schmiedeberg's Archives of Pharmacology. 1996;354(6):746-754.
    PUB | DOI
     
  • [5]
    1996 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984512
    Nawrath H, Wegener J. Kinetics and state-dependent effects of verapamil on cardiac L-type calcium channels. Naunyn-Schmiedeberg's Archives of Pharmacology. 1996;355(1):79-86.
    PUB | DOI
     
  • [4]
    1995 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984515
    Wegener J, Nawrath H. Extracellular site of action of phenylalkylamines on L-type calcium current in rat ventricular myocytes. Naunyn-Schmiedeberg's Archives of Pharmacology. 1995;352(3).
    PUB | DOI
     
  • [3]
    1995 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984514
    Wegener J, Nawrath H. Alkalinisation does not modify the effect of verapamil on myocardial Ca2+ current. European Journal of Pharmacology. 1995;287(1):89-92.
    PUB | DOI
     
  • [2]
    1993 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984640
    Wegener J, Boekhoff I, Tareilus E, Breer H. Olfactory signalling in antennal receptor neurones of the locust (Locusta migratoria). Journal of Insect Physiology. 1993;39(2):153-163.
    PUB | DOI | Download (ext.)
     
  • [1]
    1992 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2984636
    Wegener J, Tareilus E, Breer H. Characterization of calcium-dependent potassium channels in antennal receptor neurones of Locusta migratoria. Journal of Insect Physiology. 1992;38(4):237-248.
    PUB | DOI
     

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