40 Publikationen
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2020 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2949613Bakonyi, D., Toelzer, C., Stricker, M., Hummel, W., Niefind, K., and Gröger, H. (2020). Expanding the Application Range of Microbial Oxidoreductases by an Alcohol Dehydrogenase from Comamonas testosteroni with a Broad Substrate Spectrum and pH Profile. Catalysts 10:1281.PUB | PDF | DOI | WoS
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2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2916563Bakonyi, D., and Hummel, W. (2017). Cloning, expression, and biochemical characterization of a novel NADP(+)-dependent 7 alpha-hydroxysteroid dehydrogenase from Clostridium difficile and its application for the oxidation of bile acids. ENZYME AND MICROBIAL TECHNOLOGY 99, 16-24.PUB | DOI | WoS | PubMed | Europe PMC
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2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2909081Rulli, G., Duangdee, N., Hummel, W., Berkessel, A., and Gröger, H. (2017). First Tandem-Type One-Pot Process Combining Asymmetric Organo- and Biocatalytic Reactions in Aqueous Media Exemplified for the Enantioselective and Diastereoselective Synthesis of 1,3-Diols. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY 2017, 812-817.PUB | DOI | WoS
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2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2909084Biermann, M., Bakonyi, D., Hummel, W., and Gröger, H. (2017). Design of recombinant whole-cell catalysts for double reduction of C=C and C=O bonds in enals and application in the synthesis of Guerbet alcohols as industrial bulk chemicals for lubricants. GREEN CHEMISTRY 19, 405-410.PUB | DOI | WoS
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2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2904890Bulut, D., Duangdee, N., Gröger, H., Berkessel, A., and Hummel, W. (2016). Screening, Molecular Cloning, and Biochemical Characterization of an Alcohol Dehydrogenase from Pichia pastoris Useful for the Kinetic Resolution of a Racemic β-Hydroxy-β-trifluoromethyl Ketone. Chembiochem 17, 1349-1358.PUB | DOI | WoS | PubMed | Europe PMC
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2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2764353Metzner, R., Hummel, W., Wetterich, F., Koenig, B., and Gröger, H. (2015). Integrated Biocatalysis in Multistep Drug Synthesis without Intermediate Isolation: A de Novo Approach toward a Rosuvastatin Key Building Block. Organic Process Research & Development 19, 635-638.PUB | DOI | WoS
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2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2721884Schmidt, S., Scherkus, C., Muschiol, J., Menyes, U., Winkler, T., Hummel, W., Gröger, H., Liese, A., Herz, H. - G., and Bornscheuer, U. T. (2015). An Enzyme Cascade Synthesis of ε-Caprolactone and its Oligomers. Angewandte Chemie (International ed. in English) 54, 2784-2787.PUB | DOI | WoS | PubMed | Europe PMC
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2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2729781Sato, H., Hummel, W., and Gröger, H. (2015). Cooperative Catalysis of Noncompatible Catalysts through Compartmentalization: Wacker Oxidation and Enzymatic Reduction in a One-Pot Process in Aqueous Media. Angewandte Chemie (International ed. in English) 54, 4488-4492.PUB | DOI | WoS | PubMed | Europe PMC
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2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2759821Engels, L., Henze, M., Hummel, W., and Elling, L. (2015). Enzyme Module Systems for the Synthesis of Uridine 5 '-Diphospho-alpha-D-glucuronic Acid and Non-Sulfated Human Natural Killer Cell-1 (HNK-1) Epitope. Advanced Synthesis & Catalysis 357, 1751-1762.PUB | DOI | WoS
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2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2761249Bulut, D., Gröger, H., and Hummel, W. (2015). Development of a growth-dependent selection system for identification of L-threonine aldolases. Applied Microbiology and Biotechnology 99, 5875-5883.PUB | DOI | WoS | PubMed | Europe PMC
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2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2729792Heidlindemann, M., Hammel, M., Scheffler, U., Mahrwald, R., Hummel, W., Berkessel, A., and Gröger, H. (2015). Chemoenzymatic Synthesis of Vitamin B5-Intermediate (R)-Pantolactone via Combined Asymmetric Organo- and Biocatalysis. The Journal of Organic Chemistry 80, 3387-3396.PUB | DOI | WoS | PubMed | Europe PMC
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2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2677387Winkler, T., Gröger, H., and Hummel, W. (2014). Enantioselective Rearrangement Coupled with Water Addition: Direct Synthesis of Enantiomerically Pure Saturated Carboxylic Acids from a, b- Unsaturated Aldehydes. ChemCatChem 6, 961-964.PUB | DOI | WoS
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2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2708863Müller, C. A., Dennig, A., Welters, T., Winkler, T., Ruff, A. J., Hummel, W., Gröger, H., and Schwaneberg, U. (2014). Whole-cell double oxidation of n-heptane. Journal of biotechnology 191, 196-204.PUB | DOI | WoS | PubMed | Europe PMC
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2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2708851Hummel, W., and Gröger, H. (2014). Strategies for regeneration of nicotinamide coenzymes emphasizing self-sufficient closed-loop recycling systems. Journal of biotechnology 191, 22-31.PUB | DOI | WoS | PubMed | Europe PMC
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2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2690890Heidlindemann, M., Rulli, G., Berkessel, A., Hummel, W., and Gröger, H. (2014). Combination of Asymmetric Organo- and Biocatalytic Reactions in Organic Media Using Immobilized Catalysts in Different Compartments. ACS Catalysis 4, 1099-1103.PUB | DOI | WoS
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2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2681761Greschner, W., Lanzerath, C., Reß, T., Tenbrink, K., Borchert, S., Mix, A., Hummel, W., and Gröger, H. (2014). Artificial cofactor regeneration with an iron(III)porphyrin as NADH-oxidase mimic in the enzymatic oxidation of L-glutamate to alpha-ketoglutarate. Journal of Molecular Catalysis B Enzymatic 103, 10-15.PUB | DOI | WoS
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2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2682298Gröger, H., and Hummel, W. (2014). Combining the 'two worlds' of chemocatalysis and biocatalysis towards multi-step one-pot processes in aqueous media. Current opinion in chemical biology 19, 171-179.PUB | DOI | WoS | PubMed | Europe PMC
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2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2612864Mueller, C. A., Akkapurathu, B., Winkler, T., Staudt, S., Hummel, W., Gröger, H., and Schwaneberg, U. (2013). In Vitro Double Oxidation of n-Heptane with Direct Cofactor Regeneration. Advanced Synthesis & Catalysis 355, 1787-1798.PUB | DOI | WoS
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2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2560792Staudt, S., Burda, E., Giese, C., Müller, C. A., Marienhagen, J., Schwaneberg, U., Hummel, W., Drauz, K., and Gröger, H. (2013). Direct Oxidation of Cycloalkanes to Cycloalkanones with Oxygen in Water. Angewandte Chemie International Edition 52, 2359-2363.PUB | DOI | WoS | PubMed | Europe PMC
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2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2637130Rulli, G., Heidlindemann, M., Berkessel, A., Hummel, W., and Gröger, H. (2013). Towards catalyst compartimentation in combined chemo- and biocatalytic processes: Immobilization of alcohol dehydrogenases for the diastereoselective reduction of a β-hydroxy ketone obtained from an organocatalytic aldol reaction. Journal of biotechnology 168, 271-276.PUB | DOI | WoS | PubMed | Europe PMC
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2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2621189Burda, E., Reß, T., Winkler, T., Giese, C., Kostrov, X., Huber, T., Hummel, W., and Gröger, H. (2013). Highly Enantioselective Reduction of α-Methylated Nitroalkenes. Angewandte Chemie (International ed. in English) 52, 9323-9326.PUB | DOI | WoS | PubMed | Europe PMC
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2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2621177Staudt, S., Bornscheuer, U. T., Menyes, U., Hummel, W., and Gröger, H. (2013). Direct biocatalytic one-pot-transformation of cyclohexanol with molecular oxygen into ɛ-caprolactone. Enzyme and microbial technology 53, 288-292.PUB | DOI | WoS | PubMed | Europe PMC
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2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2471821Schnapperelle, I., Hummel, W., and Gröger, H. (2012). Formal Asymmetric Hydration of Non-Activated Alkenes in Aqueous Medium through a "Chemoenzymatic Catalytic System". Chemistry - A European Journal 18, 1073-1076.PUB | DOI | WoS | PubMed | Europe PMC
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2012 | Sammelwerksbeitrag | Veröffentlicht | PUB-ID: 2397781Hummel, W., and Gröger, H. (2012). “Reductive Amination of Keto Acids” in Enzyme Catalysis in Organic Synthesis, Drauz, K., Gröger, H., and May, O. eds., vol. 3, 3rd ed. (Weinheim: Wiley-VCH), 1165-1221.PUB
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2012 | Sammelwerksbeitrag | Veröffentlicht | PUB-ID: 2397699Gröger, H., Hummel, W., Borchert, S., and Kraußer, M. (2012). “Reduction of Ketones and Aldehydes to Alcohols” in Enzyme Catalysis in Organic Synthesis, Drauz, K., Gröger, H., and May, O. eds., vol. 2, 3rd ed. (Weinheim: Wiley-VCH).PUB
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2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2445196Borchert, S., Burda, E., Schatz, J., Hummel, W., and Gröger, H. (2012). Combination of a Suzuki cross-coupling reaction using a water-soluble palladium catalyst with an asymmetric enzymatic reduction towards a one-pot reaction in aqueous medium at room temperature. J. Mol. Catal. B: Enzym. 84, 89-93.PUB | DOI | WoS
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2012 | Sammelwerksbeitrag | Veröffentlicht | PUB-ID: 2398903Gröger, H., Hummel, W., and Metzner, R. (2012). “Asymmetric Biocatalytic Reduction of Ketones” in Synthetic Methods VI – Enzymatic and Semi-Enzymatic, Carreira, E. M., and Yamamoto, H. eds. Comprehensive Chirality, vol. 7, (Oxford: Elsevier), 181-215.PUB | DOI
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2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2407538Maid, H., Böhm, P., Huber, S. M., Bauer, W., Hummel, W., Jux, N., and Gröger, H. (2011). Eisenkatalyse zur In-situ-Regenerierung oxidierter Cofaktoren durch Aktivierung und Reduktion von O2: ein synthetisches Metallporphyrin als biomimetische NAD(P)H-Oxidase. Angewandte Chemie 123, 2445-2448.PUB | DOI
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2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2344721Maid, H., Boehm, P., Huber, S. M., Bauer, W., Hummel, W., Jux, N., and Gröger, H. (2011). Iron Catalysis for In Situ Regeneration of Oxidized Cofactors by Activation and Reduction of Molecular Oxygen: A Synthetic Metalloporphyrin as a Biomimetic NAD(P)H Oxidase. Angewandte Chemie International Edition 50, 2397-2400.PUB | DOI | WoS | PubMed | Europe PMC
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2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2407610Rulli, G., Duangdee, N., Baer, K., Hummel, W., Berkessel, A., and Gröger, H. (2011). Gesteuerte kinetisch oder thermodynamisch kontrollierte Organokatalyse und Anwendung in der chemoenzymatischen Synthese. Angew. Chem. 123, 8092-8095.PUB | DOI
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2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2344713Rulli, G., Duangdee, N., Baer, K., Hummel, W., Berkessel, A., and Gröger, H. (2011). Direction of Kinetically versus Thermodynamically Controlled Organocatalysis and Its Application in Chemoenzymatic Synthesis. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 50, 7944-7947.PUB | DOI | WoS | PubMed | Europe PMC
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2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2344730Richter, N., Gröger, H., and Hummel, W. (2011). Asymmetric reduction of activated alkenes using an enoate reductase from Gluconobacter oxydans. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 89, 79-89.PUB | DOI | WoS | PubMed | Europe PMC
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2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2344704Krausser, M., Winkler, T., Richter, N., Dommer, S., Fingerhut, A., Hummel, W., and Gröger, H. (2011). Combination of C=C Bond Formation by Wittig Reaction and Enzymatic C=C Bond Reduction in a One-Pot Process in Water. ChemCatChem 3, 293-296.PUB | DOI | WoS
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2010 | Sammelwerksbeitrag | Veröffentlicht | PUB-ID: 2344784Weckbecker, A., Gröger, H., and Hummel, W. (2010). “Regeneration of Nicotinamide Coenzymes: Principles and Applications for the Synthesis of Chiral Compounds” in BIOSYSTEMS ENGINEERING I: CREATING SUPERIOR BIOCATALYSTS, Wittmann, C., and Krull, W. R. eds. Advances in Biochemical Engineering-Biotechnology, vol. 120, (Berlin, Heidelberg: Springer Berlin Heidelberg), 195-242.PUB | DOI | WoS | PubMed | Europe PMC
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2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2344737Dückers, N., Baer, K., Simon, S., Gröger, H., and Hummel, W. (2010). Threonine aldolases-screening, properties and applications in the synthesis of non-proteinogenic beta-hydroxy-alpha-amino acids. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 88, 409-424.PUB | DOI | WoS | PubMed | Europe PMC
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2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2344761Baer, K., Dueckers, N., Hummel, W., and Gröger, H. (2010). Expanding the Application Range of Aldolases: Novel Asymmetric Syntheses of alpha-Methylated beta-Hydroxy alpha-Amino Acids and beta-Amino Alcohols. ChemCatChem 2, 939-942.PUB | DOI | WoS
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2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2344772Neupert, A., Ress, T., Wittmann, J., Hummel, W., and Gröger, H. (2010). Enantioselective Biocatalytic Reduction of Non-protected Hydroxyacetophenones. Zeitschrift für Naturforschung. Section B, a journal of chemical sciences 65, 337-340.PUB | DOI | WoS