40 Publikationen

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  • [40]
    2020 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2949613 OA
    Bakonyi D, Toelzer C, Stricker M, Hummel W, Niefind K, Gröger H (2020)
    Expanding the Application Range of Microbial Oxidoreductases by an Alcohol Dehydrogenase from Comamonas testosteroni with a Broad Substrate Spectrum and pH Profile.
    Catalysts 10(11): 1281.
    PUB | PDF | DOI | WoS
     
  • [39]
    2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2916563
    Bakonyi D, Hummel W (2017)
    Cloning, expression, and biochemical characterization of a novel NADP(+)-dependent 7 alpha-hydroxysteroid dehydrogenase from Clostridium difficile and its application for the oxidation of bile acids.
    ENZYME AND MICROBIAL TECHNOLOGY 99: 16-24.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [38]
    2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2909081
    Rulli G, Duangdee N, Hummel W, Berkessel A, Gröger H (2017)
    First Tandem-Type One-Pot Process Combining Asymmetric Organo- and Biocatalytic Reactions in Aqueous Media Exemplified for the Enantioselective and Diastereoselective Synthesis of 1,3-Diols.
    EUROPEAN JOURNAL OF ORGANIC CHEMISTRY 2017(4): 812-817.
    PUB | DOI | WoS
     
  • [37]
    2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2909084
    Biermann M, Bakonyi D, Hummel W, Gröger H (2017)
    Design of recombinant whole-cell catalysts for double reduction of C=C and C=O bonds in enals and application in the synthesis of Guerbet alcohols as industrial bulk chemicals for lubricants.
    GREEN CHEMISTRY 19(2): 405-410.
    PUB | DOI | WoS
     
  • [36]
    2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2904890
    Bulut D, Duangdee N, Gröger H, Berkessel A, Hummel W (2016)
    Screening, Molecular Cloning, and Biochemical Characterization of an Alcohol Dehydrogenase from Pichia pastoris Useful for the Kinetic Resolution of a Racemic β-Hydroxy-β-trifluoromethyl Ketone.
    Chembiochem 17(14): 1349-1358.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [35]
    2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2917152
    Biermann M, Gruß H, Hummel W, Gröger H (2016)
    Guerbet Alcohols: From Processes under Harsh Conditions to Synthesis at Room Temperature under Ambient Pressure.
    CHEMCATCHEM 8(5): 895-899.
    PUB | DOI | WoS
     
  • [34]
    2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2764353
    Metzner R, Hummel W, Wetterich F, Koenig B, Gröger H (2015)
    Integrated Biocatalysis in Multistep Drug Synthesis without Intermediate Isolation: A de Novo Approach toward a Rosuvastatin Key Building Block.
    Organic Process Research & Development 19(6): 635-638.
    PUB | DOI | WoS
     
  • [33]
    2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2721884
    Schmidt S, Scherkus C, Muschiol J, Menyes U, Winkler T, Hummel W, Gröger H, Liese A, Herz H-G, Bornscheuer UT (2015)
    An Enzyme Cascade Synthesis of ε-Caprolactone and its Oligomers.
    Angewandte Chemie (International ed. in English) 54(9): 2784-2787.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [32]
    2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2729781
    Sato H, Hummel W, Gröger H (2015)
    Cooperative Catalysis of Noncompatible Catalysts through Compartmentalization: Wacker Oxidation and Enzymatic Reduction in a One-Pot Process in Aqueous Media.
    Angewandte Chemie (International ed. in English) 54(15): 4488-4492.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [31]
    2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2759821
    Engels L, Henze M, Hummel W, Elling L (2015)
    Enzyme Module Systems for the Synthesis of Uridine 5 '-Diphospho-alpha-D-glucuronic Acid and Non-Sulfated Human Natural Killer Cell-1 (HNK-1) Epitope.
    Advanced Synthesis & Catalysis 357(8): 1751-1762.
    PUB | DOI | WoS
     
  • [30]
    2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2758474
    Reß T, Hummel W, Hanlon SP, Iding H, Gröger H (2015)
    The Organic-Synthetic Potential of Recombinant Ene Reductases: Substrate-Scope Evaluation and Process Optimization.
    ChemCatChem 7(8): 1302-1311.
    PUB | DOI | WoS
     
  • [29]
    2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2761249
    Bulut D, Gröger H, Hummel W (2015)
    Development of a growth-dependent selection system for identification of L-threonine aldolases.
    Applied Microbiology and Biotechnology 99(14): 5875-5883.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [28]
    2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2729792
    Heidlindemann M, Hammel M, Scheffler U, Mahrwald R, Hummel W, Berkessel A, Gröger H (2015)
    Chemoenzymatic Synthesis of Vitamin B5-Intermediate (R)-Pantolactone via Combined Asymmetric Organo- and Biocatalysis.
    The Journal of Organic Chemistry 80(7): 3387-3396.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [27]
    2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2677387
    Winkler T, Gröger H, Hummel W (2014)
    Enantioselective Rearrangement Coupled with Water Addition: Direct Synthesis of Enantiomerically Pure Saturated Carboxylic Acids from a, b- Unsaturated Aldehydes.
    ChemCatChem 6(4): 961-964.
    PUB | DOI | WoS
     
  • [26]
    2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2708863
    Müller CA, Dennig A, Welters T, Winkler T, Ruff AJ, Hummel W, Gröger H, Schwaneberg U (2014)
    Whole-cell double oxidation of n-heptane.
    Journal of biotechnology 191: 196-204.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [25]
    2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2708851
    Hummel W, Gröger H (2014)
    Strategies for regeneration of nicotinamide coenzymes emphasizing self-sufficient closed-loop recycling systems.
    Journal of biotechnology 191: 22-31.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [24]
    2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2690890
    Heidlindemann M, Rulli G, Berkessel A, Hummel W, Gröger H (2014)
    Combination of Asymmetric Organo- and Biocatalytic Reactions in Organic Media Using Immobilized Catalysts in Different Compartments.
    ACS Catalysis 4(4): 1099-1103.
    PUB | DOI | WoS
     
  • [23]
    2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2681761
    Greschner W, Lanzerath C, Reß T, Tenbrink K, Borchert S, Mix A, Hummel W, Gröger H (2014)
    Artificial cofactor regeneration with an iron(III)porphyrin as NADH-oxidase mimic in the enzymatic oxidation of L-glutamate to alpha-ketoglutarate.
    Journal of Molecular Catalysis B Enzymatic 103: 10-15.
    PUB | DOI | WoS
     
  • [22]
    2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2682298
    Gröger H, Hummel W (2014)
    Combining the 'two worlds' of chemocatalysis and biocatalysis towards multi-step one-pot processes in aqueous media.
    Current opinion in chemical biology 19: 171-179.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [21]
    2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2612864
    Mueller CA, Akkapurathu B, Winkler T, Staudt S, Hummel W, Gröger H, Schwaneberg U (2013)
    In Vitro Double Oxidation of n-Heptane with Direct Cofactor Regeneration.
    Advanced Synthesis & Catalysis 355(9): 1787-1798.
    PUB | DOI | WoS
     
  • [20]
    2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2560792
    Staudt S, Burda E, Giese C, Müller CA, Marienhagen J, Schwaneberg U, Hummel W, Drauz K, Gröger H (2013)
    Direct Oxidation of Cycloalkanes to Cycloalkanones with Oxygen in Water.
    Angewandte Chemie International Edition 52(8): 2359-2363.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [19]
    2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2637130
    Rulli G, Heidlindemann M, Berkessel A, Hummel W, Gröger H (2013)
    Towards catalyst compartimentation in combined chemo- and biocatalytic processes: Immobilization of alcohol dehydrogenases for the diastereoselective reduction of a β-hydroxy ketone obtained from an organocatalytic aldol reaction.
    Journal of biotechnology 168(3): 271-276.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [18]
    2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2621189
    Burda E, Reß T, Winkler T, Giese C, Kostrov X, Huber T, Hummel W, Gröger H (2013)
    Highly Enantioselective Reduction of α-Methylated Nitroalkenes.
    Angewandte Chemie (International ed. in English) 52(35): 9323-9326.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [17]
    2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2621177
    Staudt S, Bornscheuer UT, Menyes U, Hummel W, Gröger H (2013)
    Direct biocatalytic one-pot-transformation of cyclohexanol with molecular oxygen into ɛ-caprolactone.
    Enzyme and microbial technology 53(4): 288-292.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [16]
    2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2471821
    Schnapperelle I, Hummel W, Gröger H (2012)
    Formal Asymmetric Hydration of Non-Activated Alkenes in Aqueous Medium through a "Chemoenzymatic Catalytic System".
    Chemistry - A European Journal 18(4): 1073-1076.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [15]
    2012 | Sammelwerksbeitrag | Veröffentlicht | PUB-ID: 2397781
    Hummel W, Gröger H (2012)
    Reductive Amination of Keto Acids.
    In: Enzyme Catalysis in Organic Synthesis. Drauz K, Gröger H, May O (Eds);3. 3rd ed. Weinheim: Wiley-VCH: 1165-1221.
    PUB
     
  • [14]
    2012 | Sammelwerksbeitrag | Veröffentlicht | PUB-ID: 2397699
    Gröger H, Hummel W, Borchert S, Kraußer M (2012)
    Reduction of Ketones and Aldehydes to Alcohols.
    In: Enzyme Catalysis in Organic Synthesis. Drauz K, Gröger H, May O (Eds);2. 3rd ed. Weinheim: Wiley-VCH.
    PUB
     
  • [13]
    2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2445196
    Borchert S, Burda E, Schatz J, Hummel W, Gröger H (2012)
    Combination of a Suzuki cross-coupling reaction using a water-soluble palladium catalyst with an asymmetric enzymatic reduction towards a one-pot reaction in aqueous medium at room temperature.
    J. Mol. Catal. B: Enzym. 84(SI): 89-93.
    PUB | DOI | WoS
     
  • [12]
    2012 | Sammelwerksbeitrag | Veröffentlicht | PUB-ID: 2398903
    Gröger H, Hummel W, Metzner R (2012)
    Asymmetric Biocatalytic Reduction of Ketones.
    In: Synthetic Methods VI – Enzymatic and Semi-Enzymatic. Carreira EM, Yamamoto H (Eds); Comprehensive Chirality, 7. Oxford: Elsevier: 181-215.
    PUB | DOI
     
  • [11]
    2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2407538
    Maid H, Böhm P, Huber SM, Bauer W, Hummel W, Jux N, Gröger H (2011)
    Eisenkatalyse zur In-situ-Regenerierung oxidierter Cofaktoren durch Aktivierung und Reduktion von O2: ein synthetisches Metallporphyrin als biomimetische NAD(P)H-Oxidase.
    Angewandte Chemie 123(10): 2445-2448.
    PUB | DOI
     
  • [10]
    2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2344721
    Maid H, Boehm P, Huber SM, Bauer W, Hummel W, Jux N, Gröger H (2011)
    Iron Catalysis for In Situ Regeneration of Oxidized Cofactors by Activation and Reduction of Molecular Oxygen: A Synthetic Metalloporphyrin as a Biomimetic NAD(P)H Oxidase.
    Angewandte Chemie International Edition 50(10): 2397-2400.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [9]
    2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2407610
    Rulli G, Duangdee N, Baer K, Hummel W, Berkessel A, Gröger H (2011)
    Gesteuerte kinetisch oder thermodynamisch kontrollierte Organokatalyse und Anwendung in der chemoenzymatischen Synthese.
    Angew. Chem. 123(34): 8092-8095.
    PUB | DOI
     
  • [8]
    2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2344713
    Rulli G, Duangdee N, Baer K, Hummel W, Berkessel A, Gröger H (2011)
    Direction of Kinetically versus Thermodynamically Controlled Organocatalysis and Its Application in Chemoenzymatic Synthesis.
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 50(34): 7944-7947.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [7]
    2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2344730
    Richter N, Gröger H, Hummel W (2011)
    Asymmetric reduction of activated alkenes using an enoate reductase from Gluconobacter oxydans.
    APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 89(1): 79-89.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [6]
    2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2344704
    Krausser M, Winkler T, Richter N, Dommer S, Fingerhut A, Hummel W, Gröger H (2011)
    Combination of C=C Bond Formation by Wittig Reaction and Enzymatic C=C Bond Reduction in a One-Pot Process in Water.
    ChemCatChem 3(2): 293-296.
    PUB | DOI | WoS
     
  • [5]
    2010 | Sammelwerksbeitrag | Veröffentlicht | PUB-ID: 2344784
    Weckbecker A, Gröger H, Hummel W (2010)
    Regeneration of Nicotinamide Coenzymes: Principles and Applications for the Synthesis of Chiral Compounds.
    In: BIOSYSTEMS ENGINEERING I: CREATING SUPERIOR BIOCATALYSTS. Wittmann C, Krull WR (Eds); Advances in Biochemical Engineering-Biotechnology, 120. Berlin, Heidelberg: Springer Berlin Heidelberg: 195-242.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [4]
    2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2344737
    Dückers N, Baer K, Simon S, Gröger H, Hummel W (2010)
    Threonine aldolases-screening, properties and applications in the synthesis of non-proteinogenic beta-hydroxy-alpha-amino acids.
    APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 88(2): 409-424.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [3]
    2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2344778
    Burda E, Bauer W, Hummel W, Gröger H (2010)
    Enantio- and Diastereoselective Chemoenzymatic Synthesis of C2-Symmetric Biaryl-Containing Diols.
    ChemCatChem 2(1): 67-72.
    PUB | DOI | WoS
     
  • [2]
    2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2344761
    Baer K, Dueckers N, Hummel W, Gröger H (2010)
    Expanding the Application Range of Aldolases: Novel Asymmetric Syntheses of alpha-Methylated beta-Hydroxy alpha-Amino Acids and beta-Amino Alcohols.
    ChemCatChem 2(8): 939-942.
    PUB | DOI | WoS
     
  • [1]
    2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2344772
    Neupert A, Ress T, Wittmann J, Hummel W, Gröger H (2010)
    Enantioselective Biocatalytic Reduction of Non-protected Hydroxyacetophenones.
    Zeitschrift für Naturforschung. Section B, a journal of chemical sciences 65(3): 337-340.
    PUB | DOI | WoS
     

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