40 Publikationen
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2020 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2949613Bakonyi D, Toelzer C, Stricker M, Hummel W, Niefind K, Gröger H (2020)PUB | PDF | DOI | WoS
Expanding the Application Range of Microbial Oxidoreductases by an Alcohol Dehydrogenase from Comamonas testosteroni with a Broad Substrate Spectrum and pH Profile.
Catalysts 10(11): 1281. -
2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2916563Bakonyi D, Hummel W (2017)PUB | DOI | WoS | PubMed | Europe PMC
Cloning, expression, and biochemical characterization of a novel NADP(+)-dependent 7 alpha-hydroxysteroid dehydrogenase from Clostridium difficile and its application for the oxidation of bile acids.
ENZYME AND MICROBIAL TECHNOLOGY 99: 16-24. -
2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2909081Rulli G, Duangdee N, Hummel W, Berkessel A, Gröger H (2017)PUB | DOI | WoS
First Tandem-Type One-Pot Process Combining Asymmetric Organo- and Biocatalytic Reactions in Aqueous Media Exemplified for the Enantioselective and Diastereoselective Synthesis of 1,3-Diols.
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY 2017(4): 812-817. -
2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2909084Biermann M, Bakonyi D, Hummel W, Gröger H (2017)PUB | DOI | WoS
Design of recombinant whole-cell catalysts for double reduction of C=C and C=O bonds in enals and application in the synthesis of Guerbet alcohols as industrial bulk chemicals for lubricants.
GREEN CHEMISTRY 19(2): 405-410. -
2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2904890Bulut D, Duangdee N, Gröger H, Berkessel A, Hummel W (2016)PUB | DOI | WoS | PubMed | Europe PMC
Screening, Molecular Cloning, and Biochemical Characterization of an Alcohol Dehydrogenase from Pichia pastoris Useful for the Kinetic Resolution of a Racemic β-Hydroxy-β-trifluoromethyl Ketone.
Chembiochem 17(14): 1349-1358. -
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2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2764353Metzner R, Hummel W, Wetterich F, Koenig B, Gröger H (2015)PUB | DOI | WoS
Integrated Biocatalysis in Multistep Drug Synthesis without Intermediate Isolation: A de Novo Approach toward a Rosuvastatin Key Building Block.
Organic Process Research & Development 19(6): 635-638. -
2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2721884Schmidt S, Scherkus C, Muschiol J, Menyes U, Winkler T, Hummel W, Gröger H, Liese A, Herz H-G, Bornscheuer UT (2015)PUB | DOI | WoS | PubMed | Europe PMC
An Enzyme Cascade Synthesis of ε-Caprolactone and its Oligomers.
Angewandte Chemie (International ed. in English) 54(9): 2784-2787. -
2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2729781Sato H, Hummel W, Gröger H (2015)PUB | DOI | WoS | PubMed | Europe PMC
Cooperative Catalysis of Noncompatible Catalysts through Compartmentalization: Wacker Oxidation and Enzymatic Reduction in a One-Pot Process in Aqueous Media.
Angewandte Chemie (International ed. in English) 54(15): 4488-4492. -
2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2759821Engels L, Henze M, Hummel W, Elling L (2015)PUB | DOI | WoS
Enzyme Module Systems for the Synthesis of Uridine 5 '-Diphospho-alpha-D-glucuronic Acid and Non-Sulfated Human Natural Killer Cell-1 (HNK-1) Epitope.
Advanced Synthesis & Catalysis 357(8): 1751-1762. -
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2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2761249Bulut D, Gröger H, Hummel W (2015)PUB | DOI | WoS | PubMed | Europe PMC
Development of a growth-dependent selection system for identification of L-threonine aldolases.
Applied Microbiology and Biotechnology 99(14): 5875-5883. -
2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2729792Heidlindemann M, Hammel M, Scheffler U, Mahrwald R, Hummel W, Berkessel A, Gröger H (2015)PUB | DOI | WoS | PubMed | Europe PMC
Chemoenzymatic Synthesis of Vitamin B5-Intermediate (R)-Pantolactone via Combined Asymmetric Organo- and Biocatalysis.
The Journal of Organic Chemistry 80(7): 3387-3396. -
2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2677387Winkler T, Gröger H, Hummel W (2014)PUB | DOI | WoS
Enantioselective Rearrangement Coupled with Water Addition: Direct Synthesis of Enantiomerically Pure Saturated Carboxylic Acids from a, b- Unsaturated Aldehydes.
ChemCatChem 6(4): 961-964. -
2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2708863Müller CA, Dennig A, Welters T, Winkler T, Ruff AJ, Hummel W, Gröger H, Schwaneberg U (2014)PUB | DOI | WoS | PubMed | Europe PMC
Whole-cell double oxidation of n-heptane.
Journal of biotechnology 191: 196-204. -
2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2708851Hummel W, Gröger H (2014)PUB | DOI | WoS | PubMed | Europe PMC
Strategies for regeneration of nicotinamide coenzymes emphasizing self-sufficient closed-loop recycling systems.
Journal of biotechnology 191: 22-31. -
2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2690890Heidlindemann M, Rulli G, Berkessel A, Hummel W, Gröger H (2014)PUB | DOI | WoS
Combination of Asymmetric Organo- and Biocatalytic Reactions in Organic Media Using Immobilized Catalysts in Different Compartments.
ACS Catalysis 4(4): 1099-1103. -
2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2681761Greschner W, Lanzerath C, Reß T, Tenbrink K, Borchert S, Mix A, Hummel W, Gröger H (2014)PUB | DOI | WoS
Artificial cofactor regeneration with an iron(III)porphyrin as NADH-oxidase mimic in the enzymatic oxidation of L-glutamate to alpha-ketoglutarate.
Journal of Molecular Catalysis B Enzymatic 103: 10-15. -
2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2682298Gröger H, Hummel W (2014)PUB | DOI | WoS | PubMed | Europe PMC
Combining the 'two worlds' of chemocatalysis and biocatalysis towards multi-step one-pot processes in aqueous media.
Current opinion in chemical biology 19: 171-179. -
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2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2560792Staudt S, Burda E, Giese C, Müller CA, Marienhagen J, Schwaneberg U, Hummel W, Drauz K, Gröger H (2013)PUB | DOI | WoS | PubMed | Europe PMC
Direct Oxidation of Cycloalkanes to Cycloalkanones with Oxygen in Water.
Angewandte Chemie International Edition 52(8): 2359-2363. -
2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2637130Rulli G, Heidlindemann M, Berkessel A, Hummel W, Gröger H (2013)PUB | DOI | WoS | PubMed | Europe PMC
Towards catalyst compartimentation in combined chemo- and biocatalytic processes: Immobilization of alcohol dehydrogenases for the diastereoselective reduction of a β-hydroxy ketone obtained from an organocatalytic aldol reaction.
Journal of biotechnology 168(3): 271-276. -
2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2621189Burda E, Reß T, Winkler T, Giese C, Kostrov X, Huber T, Hummel W, Gröger H (2013)PUB | DOI | WoS | PubMed | Europe PMC
Highly Enantioselective Reduction of α-Methylated Nitroalkenes.
Angewandte Chemie (International ed. in English) 52(35): 9323-9326. -
2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2621177Staudt S, Bornscheuer UT, Menyes U, Hummel W, Gröger H (2013)PUB | DOI | WoS | PubMed | Europe PMC
Direct biocatalytic one-pot-transformation of cyclohexanol with molecular oxygen into ɛ-caprolactone.
Enzyme and microbial technology 53(4): 288-292. -
2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2471821Schnapperelle I, Hummel W, Gröger H (2012)PUB | DOI | WoS | PubMed | Europe PMC
Formal Asymmetric Hydration of Non-Activated Alkenes in Aqueous Medium through a "Chemoenzymatic Catalytic System".
Chemistry - A European Journal 18(4): 1073-1076. -
2012 | Sammelwerksbeitrag | Veröffentlicht | PUB-ID: 2397781Hummel W, Gröger H (2012)PUB
Reductive Amination of Keto Acids.
In: Enzyme Catalysis in Organic Synthesis. Drauz K, Gröger H, May O (Eds);3. 3rd ed. Weinheim: Wiley-VCH: 1165-1221. -
2012 | Sammelwerksbeitrag | Veröffentlicht | PUB-ID: 2397699Gröger H, Hummel W, Borchert S, Kraußer M (2012)PUB
Reduction of Ketones and Aldehydes to Alcohols.
In: Enzyme Catalysis in Organic Synthesis. Drauz K, Gröger H, May O (Eds);2. 3rd ed. Weinheim: Wiley-VCH. -
2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2445196Borchert S, Burda E, Schatz J, Hummel W, Gröger H (2012)PUB | DOI | WoS
Combination of a Suzuki cross-coupling reaction using a water-soluble palladium catalyst with an asymmetric enzymatic reduction towards a one-pot reaction in aqueous medium at room temperature.
J. Mol. Catal. B: Enzym. 84(SI): 89-93. -
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2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2407538Maid H, Böhm P, Huber SM, Bauer W, Hummel W, Jux N, Gröger H (2011)PUB | DOI
Eisenkatalyse zur In-situ-Regenerierung oxidierter Cofaktoren durch Aktivierung und Reduktion von O2: ein synthetisches Metallporphyrin als biomimetische NAD(P)H-Oxidase.
Angewandte Chemie 123(10): 2445-2448. -
2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2344721Maid H, Boehm P, Huber SM, Bauer W, Hummel W, Jux N, Gröger H (2011)PUB | DOI | WoS | PubMed | Europe PMC
Iron Catalysis for In Situ Regeneration of Oxidized Cofactors by Activation and Reduction of Molecular Oxygen: A Synthetic Metalloporphyrin as a Biomimetic NAD(P)H Oxidase.
Angewandte Chemie International Edition 50(10): 2397-2400. -
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2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2344713Rulli G, Duangdee N, Baer K, Hummel W, Berkessel A, Gröger H (2011)PUB | DOI | WoS | PubMed | Europe PMC
Direction of Kinetically versus Thermodynamically Controlled Organocatalysis and Its Application in Chemoenzymatic Synthesis.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 50(34): 7944-7947. -
2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2344730Richter N, Gröger H, Hummel W (2011)PUB | DOI | WoS | PubMed | Europe PMC
Asymmetric reduction of activated alkenes using an enoate reductase from Gluconobacter oxydans.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 89(1): 79-89. -
2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2344704Krausser M, Winkler T, Richter N, Dommer S, Fingerhut A, Hummel W, Gröger H (2011)PUB | DOI | WoS
Combination of C=C Bond Formation by Wittig Reaction and Enzymatic C=C Bond Reduction in a One-Pot Process in Water.
ChemCatChem 3(2): 293-296. -
2010 | Sammelwerksbeitrag | Veröffentlicht | PUB-ID: 2344784Weckbecker A, Gröger H, Hummel W (2010)PUB | DOI | WoS | PubMed | Europe PMC
Regeneration of Nicotinamide Coenzymes: Principles and Applications for the Synthesis of Chiral Compounds.
In: BIOSYSTEMS ENGINEERING I: CREATING SUPERIOR BIOCATALYSTS. Wittmann C, Krull WR (Eds); Advances in Biochemical Engineering-Biotechnology, 120. Berlin, Heidelberg: Springer Berlin Heidelberg: 195-242. -
2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2344737Dückers N, Baer K, Simon S, Gröger H, Hummel W (2010)PUB | DOI | WoS | PubMed | Europe PMC
Threonine aldolases-screening, properties and applications in the synthesis of non-proteinogenic beta-hydroxy-alpha-amino acids.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 88(2): 409-424. -
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2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2344772Neupert A, Ress T, Wittmann J, Hummel W, Gröger H (2010)PUB | DOI | WoS
Enantioselective Biocatalytic Reduction of Non-protected Hydroxyacetophenones.
Zeitschrift für Naturforschung. Section B, a journal of chemical sciences 65(3): 337-340.