40 Publikationen

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  • [40]
    2020 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2949613 OA
    Bakonyi, Daniel, Toelzer, Christine, Stricker, Michael, Hummel, Werner, Niefind, Karsten, and Gröger, Harald. 2020. “Expanding the Application Range of Microbial Oxidoreductases by an Alcohol Dehydrogenase from Comamonas testosteroni with a Broad Substrate Spectrum and pH Profile”. Catalysts 10 (11): 1281.
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  • [39]
    2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2916563
    Bakonyi, Daniel, and Hummel, Werner. 2017. “Cloning, expression, and biochemical characterization of a novel NADP(+)-dependent 7 alpha-hydroxysteroid dehydrogenase from Clostridium difficile and its application for the oxidation of bile acids”. ENZYME AND MICROBIAL TECHNOLOGY 99: 16-24.
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  • [38]
    2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2909081
    Rulli, Giuseppe, Duangdee, Nongnaphat, Hummel, Werner, Berkessel, Albrecht, and Gröger, Harald. 2017. “First Tandem-Type One-Pot Process Combining Asymmetric Organo- and Biocatalytic Reactions in Aqueous Media Exemplified for the Enantioselective and Diastereoselective Synthesis of 1,3-Diols”. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY 2017 (4): 812-817.
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  • [37]
    2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2909084
    Biermann, Marc, Bakonyi, Daniel, Hummel, Werner, and Gröger, Harald. 2017. “Design of recombinant whole-cell catalysts for double reduction of C=C and C=O bonds in enals and application in the synthesis of Guerbet alcohols as industrial bulk chemicals for lubricants”. GREEN CHEMISTRY 19 (2): 405-410.
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  • [36]
    2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2904890
    Bulut, Dalia, Duangdee, Nongnaphat, Gröger, Harald, Berkessel, Albrecht, and Hummel, Werner. 2016. “Screening, Molecular Cloning, and Biochemical Characterization of an Alcohol Dehydrogenase from Pichia pastoris Useful for the Kinetic Resolution of a Racemic β-Hydroxy-β-trifluoromethyl Ketone”. Chembiochem 17 (14): 1349-1358.
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  • [35]
    2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2917152
    Biermann, Marc, Gruß, Hendrik, Hummel, Werner, and Gröger, Harald. 2016. “Guerbet Alcohols: From Processes under Harsh Conditions to Synthesis at Room Temperature under Ambient Pressure”. CHEMCATCHEM 8 (5): 895-899.
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  • [34]
    2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2764353
    Metzner, Richard, Hummel, Werner, Wetterich, Frank, Koenig, Burghard, and Gröger, Harald. 2015. “Integrated Biocatalysis in Multistep Drug Synthesis without Intermediate Isolation: A de Novo Approach toward a Rosuvastatin Key Building Block”. Organic Process Research & Development 19 (6): 635-638.
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  • [33]
    2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2721884
    Schmidt, Sandy, Scherkus, Christian, Muschiol, Jan, Menyes, Ulf, Winkler, Till, Hummel, Werner, Gröger, Harald, Liese, Andreas, Herz, Hans-Georg, and Bornscheuer, Uwe T. 2015. “An Enzyme Cascade Synthesis of ε-Caprolactone and its Oligomers”. Angewandte Chemie (International ed. in English) 54 (9): 2784-2787.
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  • [32]
    2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2729781
    Sato, Hirofumi, Hummel, Werner, and Gröger, Harald. 2015. “Cooperative Catalysis of Noncompatible Catalysts through Compartmentalization: Wacker Oxidation and Enzymatic Reduction in a One-Pot Process in Aqueous Media”. Angewandte Chemie (International ed. in English) 54 (15): 4488-4492.
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  • [31]
    2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2759821
    Engels, Leonie, Henze, Manja, Hummel, Werner, and Elling, Lothar. 2015. “Enzyme Module Systems for the Synthesis of Uridine 5 '-Diphospho-alpha-D-glucuronic Acid and Non-Sulfated Human Natural Killer Cell-1 (HNK-1) Epitope”. Advanced Synthesis & Catalysis 357 (8): 1751-1762.
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  • [30]
    2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2758474
    Reß, Tina, Hummel, Werner, Hanlon, Steven P., Iding, Hans, and Gröger, Harald. 2015. “The Organic-Synthetic Potential of Recombinant Ene Reductases: Substrate-Scope Evaluation and Process Optimization”. ChemCatChem 7 (8): 1302-1311.
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  • [29]
    2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2761249
    Bulut, Dalia, Gröger, Harald, and Hummel, Werner. 2015. “Development of a growth-dependent selection system for identification of L-threonine aldolases”. Applied Microbiology and Biotechnology 99 (14): 5875-5883.
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  • [28]
    2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2729792
    Heidlindemann, Marcel, Hammel, Matthias, Scheffler, Ulf, Mahrwald, Rainer, Hummel, Werner, Berkessel, Albrecht, and Gröger, Harald. 2015. “Chemoenzymatic Synthesis of Vitamin B5-Intermediate (R)-Pantolactone via Combined Asymmetric Organo- and Biocatalysis”. The Journal of Organic Chemistry 80 (7): 3387-3396.
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  • [27]
    2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2677387
    Winkler, Till, Gröger, Harald, and Hummel, Werner. 2014. “Enantioselective Rearrangement Coupled with Water Addition: Direct Synthesis of Enantiomerically Pure Saturated Carboxylic Acids from a, b- Unsaturated Aldehydes”. ChemCatChem 6 (4): 961-964.
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  • [26]
    2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2708863
    Müller, Christina A., Dennig, Alexander, Welters, Tim, Winkler, Till, Ruff, Anna Joelle, Hummel, Werner, Gröger, Harald, and Schwaneberg, Ulrich. 2014. “Whole-cell double oxidation of n-heptane”. Journal of biotechnology 191: 196-204.
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  • [25]
    2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2708851
    Hummel, Werner, and Gröger, Harald. 2014. “Strategies for regeneration of nicotinamide coenzymes emphasizing self-sufficient closed-loop recycling systems”. Journal of biotechnology 191: 22-31.
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  • [24]
    2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2690890
    Heidlindemann, Marcel, Rulli, Giuseppe, Berkessel, Albrecht, Hummel, Werner, and Gröger, Harald. 2014. “Combination of Asymmetric Organo- and Biocatalytic Reactions in Organic Media Using Immobilized Catalysts in Different Compartments”. ACS Catalysis 4 (4): 1099-1103.
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  • [23]
    2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2681761
    Greschner, Wilko, Lanzerath, Carsten, Reß, Tina, Tenbrink, Katharina, Borchert, Sonja, Mix, Andreas, Hummel, Werner, and Gröger, Harald. 2014. “Artificial cofactor regeneration with an iron(III)porphyrin as NADH-oxidase mimic in the enzymatic oxidation of L-glutamate to alpha-ketoglutarate”. Journal of Molecular Catalysis B Enzymatic 103: 10-15.
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  • [22]
    2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2682298
    Gröger, Harald, and Hummel, Werner. 2014. “Combining the 'two worlds' of chemocatalysis and biocatalysis towards multi-step one-pot processes in aqueous media”. Current opinion in chemical biology 19: 171-179.
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  • [21]
    2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2612864
    Mueller, Christina A., Akkapurathu, Beneeta, Winkler, Till, Staudt, Svenja, Hummel, Werner, Gröger, Harald, and Schwaneberg, Ulrich. 2013. “In Vitro Double Oxidation of n-Heptane with Direct Cofactor Regeneration”. Advanced Synthesis & Catalysis 355 (9): 1787-1798.
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  • [20]
    2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2560792
    Staudt, Svenja, Burda, Edyta, Giese, Carolin, Müller, Christina A., Marienhagen, Jan, Schwaneberg, Ulrich, Hummel, Werner, Drauz, Karlheinz, and Gröger, Harald. 2013. “Direct Oxidation of Cycloalkanes to Cycloalkanones with Oxygen in Water”. Angewandte Chemie International Edition 52 (8): 2359-2363.
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  • [19]
    2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2637130
    Rulli, Giuseppe, Heidlindemann, Marcel, Berkessel, Albrecht, Hummel, Werner, and Gröger, Harald. 2013. “Towards catalyst compartimentation in combined chemo- and biocatalytic processes: Immobilization of alcohol dehydrogenases for the diastereoselective reduction of a β-hydroxy ketone obtained from an organocatalytic aldol reaction”. Journal of biotechnology 168 (3): 271-276.
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  • [18]
    2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2621189
    Burda, Edyta, Reß, Tina, Winkler, Till, Giese, Carolin, Kostrov, Xenia, Huber, Tobias, Hummel, Werner, and Gröger, Harald. 2013. “Highly Enantioselective Reduction of α-Methylated Nitroalkenes”. Angewandte Chemie (International ed. in English) 52 (35): 9323-9326.
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  • [17]
    2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2621177
    Staudt, Svenja, Bornscheuer, Uwe T, Menyes, Ulf, Hummel, Werner, and Gröger, Harald. 2013. “Direct biocatalytic one-pot-transformation of cyclohexanol with molecular oxygen into ɛ-caprolactone”. Enzyme and microbial technology 53 (4): 288-292.
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  • [16]
    2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2471821
    Schnapperelle, Ingo, Hummel, Werner, and Gröger, Harald. 2012. “Formal Asymmetric Hydration of Non-Activated Alkenes in Aqueous Medium through a "Chemoenzymatic Catalytic System"”. Chemistry - A European Journal 18 (4): 1073-1076.
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  • [15]
    2012 | Sammelwerksbeitrag | Veröffentlicht | PUB-ID: 2397781
    Hummel, Werner, and Gröger, Harald. 2012. “Reductive Amination of Keto Acids”. In Enzyme Catalysis in Organic Synthesis, ed. Karlheinz Drauz, Harald Gröger, and Oliver May, 3rd ed., 3:1165-1221. Weinheim: Wiley-VCH.
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  • [14]
    2012 | Sammelwerksbeitrag | Veröffentlicht | PUB-ID: 2397699
    Gröger, Harald, Hummel, Werner, Borchert, Sonja, and Kraußer, Marina. 2012. “Reduction of Ketones and Aldehydes to Alcohols”. In Enzyme Catalysis in Organic Synthesis, ed. Karlheinz Drauz, Harald Gröger, and Oliver May, 3rd ed. Vol. 2. Weinheim: Wiley-VCH.
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  • [13]
    2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2445196
    Borchert, Sonja, Burda, Edyta, Schatz, Jürgen, Hummel, Werner, and Gröger, Harald. 2012. “Combination of a Suzuki cross-coupling reaction using a water-soluble palladium catalyst with an asymmetric enzymatic reduction towards a one-pot reaction in aqueous medium at room temperature”. J. Mol. Catal. B: Enzym. 84 (SI): 89-93.
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  • [12]
    2012 | Sammelwerksbeitrag | Veröffentlicht | PUB-ID: 2398903
    Gröger, Harald, Hummel, Werner, and Metzner, Richard. 2012. “Asymmetric Biocatalytic Reduction of Ketones”. In Synthetic Methods VI – Enzymatic and Semi-Enzymatic, ed. Erick M. Carreira and Hisashi Yamamoto, 7:181-215. Comprehensive Chirality. Oxford: Elsevier.
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  • [11]
    2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2407538
    Maid, H., Böhm, P., Huber, S.M., Bauer, W., Hummel, Werner, Jux, N., and Gröger, Harald. 2011. “Eisenkatalyse zur In-situ-Regenerierung oxidierter Cofaktoren durch Aktivierung und Reduktion von O2: ein synthetisches Metallporphyrin als biomimetische NAD(P)H-Oxidase”. Angewandte Chemie 123 (10): 2445-2448.
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  • [10]
    2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2344721
    Maid, Harald, Boehm, Philipp, Huber, Stefan M., Bauer, Walter, Hummel, Werner, Jux, Norbert, and Gröger, Harald. 2011. “Iron Catalysis for In Situ Regeneration of Oxidized Cofactors by Activation and Reduction of Molecular Oxygen: A Synthetic Metalloporphyrin as a Biomimetic NAD(P)H Oxidase”. Angewandte Chemie International Edition 50 (10): 2397-2400.
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  • [9]
    2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2407610
    Rulli, Giuseppe, Duangdee, Nongnaphat, Baer, Katrin, Hummel, Werner, Berkessel, Albrecht, and Gröger, Harald. 2011. “Gesteuerte kinetisch oder thermodynamisch kontrollierte Organokatalyse und Anwendung in der chemoenzymatischen Synthese”. Angew. Chem. 123 (34): 8092-8095.
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  • [8]
    2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2344713
    Rulli, Giuseppe, Duangdee, Nongnaphat, Baer, Katrin, Hummel, Werner, Berkessel, Albrecht, and Gröger, Harald. 2011. “Direction of Kinetically versus Thermodynamically Controlled Organocatalysis and Its Application in Chemoenzymatic Synthesis”. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 50 (34): 7944-7947.
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  • [7]
    2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2344730
    Richter, Nina, Gröger, Harald, and Hummel, Werner. 2011. “Asymmetric reduction of activated alkenes using an enoate reductase from Gluconobacter oxydans”. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 89 (1): 79-89.
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  • [6]
    2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2344704
    Krausser, Marina, Winkler, Till, Richter, Nina, Dommer, Sabine, Fingerhut, Anja, Hummel, Werner, and Gröger, Harald. 2011. “Combination of C=C Bond Formation by Wittig Reaction and Enzymatic C=C Bond Reduction in a One-Pot Process in Water”. ChemCatChem 3 (2): 293-296.
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  • [5]
    2010 | Sammelwerksbeitrag | Veröffentlicht | PUB-ID: 2344784
    Weckbecker, Andrea, Gröger, Harald, and Hummel, Werner. 2010. “Regeneration of Nicotinamide Coenzymes: Principles and Applications for the Synthesis of Chiral Compounds”. In BIOSYSTEMS ENGINEERING I: CREATING SUPERIOR BIOCATALYSTS, ed. C. Wittmann and W. R. Krull, 120:195-242. Advances in Biochemical Engineering-Biotechnology. Berlin, Heidelberg: Springer Berlin Heidelberg.
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  • [4]
    2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2344737
    Dückers, Nina, Baer, Katrin, Simon, Sabine, Gröger, Harald, and Hummel, Werner. 2010. “Threonine aldolases-screening, properties and applications in the synthesis of non-proteinogenic beta-hydroxy-alpha-amino acids”. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 88 (2): 409-424.
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  • [3]
    2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2344778
    Burda, Edyta, Bauer, Walter, Hummel, Werner, and Gröger, Harald. 2010. “Enantio- and Diastereoselective Chemoenzymatic Synthesis of C2-Symmetric Biaryl-Containing Diols”. ChemCatChem 2 (1): 67-72.
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  • [2]
    2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2344761
    Baer, Katrin, Dueckers, Nina, Hummel, Werner, and Gröger, Harald. 2010. “Expanding the Application Range of Aldolases: Novel Asymmetric Syntheses of alpha-Methylated beta-Hydroxy alpha-Amino Acids and beta-Amino Alcohols”. ChemCatChem 2 (8): 939-942.
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  • [1]
    2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2344772
    Neupert, Adrian, Ress, Tina, Wittmann, Jürgen, Hummel, Werner, and Gröger, Harald. 2010. “Enantioselective Biocatalytic Reduction of Non-protected Hydroxyacetophenones”. Zeitschrift für Naturforschung. Section B, a journal of chemical sciences 65 (3): 337-340.
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