40 Publikationen

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  • [40]
    2020 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2949613 OA
    D. Bakonyi, C. Toelzer, M. Stricker, W. Hummel, K. Niefind, and H. Gröger, “Expanding the Application Range of Microbial Oxidoreductases by an Alcohol Dehydrogenase from Comamonas testosteroni with a Broad Substrate Spectrum and pH Profile”, Catalysts, 2020, 10, : 1281.
    PUB | PDF | DOI | WoS
     
  • [39]
    2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2916563
    D. Bakonyi, and W. Hummel, “Cloning, expression, and biochemical characterization of a novel NADP(+)-dependent 7 alpha-hydroxysteroid dehydrogenase from Clostridium difficile and its application for the oxidation of bile acids”, ENZYME AND MICROBIAL TECHNOLOGY, 2017, 99, 16-24.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [38]
    2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2909081
    G. Rulli, N. Duangdee, W. Hummel, A. Berkessel, and H. Gröger, “First Tandem-Type One-Pot Process Combining Asymmetric Organo- and Biocatalytic Reactions in Aqueous Media Exemplified for the Enantioselective and Diastereoselective Synthesis of 1,3-Diols”, EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2017, 2017, 812-817.
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  • [37]
    2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2909084
    M. Biermann, D. Bakonyi, W. Hummel, and H. Gröger, “Design of recombinant whole-cell catalysts for double reduction of C=C and C=O bonds in enals and application in the synthesis of Guerbet alcohols as industrial bulk chemicals for lubricants”, GREEN CHEMISTRY, 2017, 19, 405-410.
    PUB | DOI | WoS
     
  • [36]
    2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2904890
    D. Bulut, N. Duangdee, H. Gröger, A. Berkessel, and W. Hummel, “Screening, Molecular Cloning, and Biochemical Characterization of an Alcohol Dehydrogenase from Pichia pastoris Useful for the Kinetic Resolution of a Racemic β-Hydroxy-β-trifluoromethyl Ketone”, Chembiochem, 2016, 17, 1349-1358.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [35]
    2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2917152
    M. Biermann, H. Gruß, W. Hummel, and H. Gröger, “Guerbet Alcohols: From Processes under Harsh Conditions to Synthesis at Room Temperature under Ambient Pressure”, CHEMCATCHEM, 2016, 8, 895-899.
    PUB | DOI | WoS
     
  • [34]
    2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2764353
    R. Metzner, W. Hummel, F. Wetterich, B. Koenig, and H. Gröger, “Integrated Biocatalysis in Multistep Drug Synthesis without Intermediate Isolation: A de Novo Approach toward a Rosuvastatin Key Building Block”, Organic Process Research & Development, 2015, 19, 635-638.
    PUB | DOI | WoS
     
  • [33]
    2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2721884
    S. Schmidt, C. Scherkus, J. Muschiol, U. Menyes, T. Winkler, W. Hummel, H. Gröger, A. Liese, H. - G. Herz, and U. T. Bornscheuer, “An Enzyme Cascade Synthesis of ε-Caprolactone and its Oligomers”, Angewandte Chemie (International ed. in English), 2015, 54, 2784-2787.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [32]
    2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2729781
    H. Sato, W. Hummel, and H. Gröger, “Cooperative Catalysis of Noncompatible Catalysts through Compartmentalization: Wacker Oxidation and Enzymatic Reduction in a One-Pot Process in Aqueous Media”, Angewandte Chemie (International ed. in English), 2015, 54, 4488-4492.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [31]
    2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2759821
    L. Engels, M. Henze, W. Hummel, and L. Elling, “Enzyme Module Systems for the Synthesis of Uridine 5 '-Diphospho-alpha-D-glucuronic Acid and Non-Sulfated Human Natural Killer Cell-1 (HNK-1) Epitope”, Advanced Synthesis & Catalysis, 2015, 357, 1751-1762.
    PUB | DOI | WoS
     
  • [30]
    2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2758474
    T. Reß, W. Hummel, S. P. Hanlon, H. Iding, and H. Gröger, “The Organic-Synthetic Potential of Recombinant Ene Reductases: Substrate-Scope Evaluation and Process Optimization”, ChemCatChem, 2015, 7, 1302-1311.
    PUB | DOI | WoS
     
  • [29]
    2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2761249
    D. Bulut, H. Gröger, and W. Hummel, “Development of a growth-dependent selection system for identification of L-threonine aldolases”, Applied Microbiology and Biotechnology, 2015, 99, 5875-5883.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [28]
    2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2729792
    M. Heidlindemann, M. Hammel, U. Scheffler, R. Mahrwald, W. Hummel, A. Berkessel, and H. Gröger, “Chemoenzymatic Synthesis of Vitamin B5-Intermediate (R)-Pantolactone via Combined Asymmetric Organo- and Biocatalysis”, The Journal of Organic Chemistry, 2015, 80, 3387-3396.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [27]
    2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2677387
    T. Winkler, H. Gröger, and W. Hummel, “Enantioselective Rearrangement Coupled with Water Addition: Direct Synthesis of Enantiomerically Pure Saturated Carboxylic Acids from a, b- Unsaturated Aldehydes”, ChemCatChem, 2014, 6, 961-964.
    PUB | DOI | WoS
     
  • [26]
    2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2708863
    C. A. Müller, A. Dennig, T. Welters, T. Winkler, A. J. Ruff, W. Hummel, H. Gröger, and U. Schwaneberg, “Whole-cell double oxidation of n-heptane”, Journal of biotechnology, 2014, 191, 196-204.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [25]
    2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2708851
    W. Hummel, and H. Gröger, “Strategies for regeneration of nicotinamide coenzymes emphasizing self-sufficient closed-loop recycling systems”, Journal of biotechnology, 2014, 191, 22-31.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [24]
    2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2690890
    M. Heidlindemann, G. Rulli, A. Berkessel, W. Hummel, and H. Gröger, “Combination of Asymmetric Organo- and Biocatalytic Reactions in Organic Media Using Immobilized Catalysts in Different Compartments”, ACS Catalysis, 2014, 4, 1099-1103.
    PUB | DOI | WoS
     
  • [23]
    2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2681761
    W. Greschner, C. Lanzerath, T. Reß, K. Tenbrink, S. Borchert, A. Mix, W. Hummel, and H. Gröger, “Artificial cofactor regeneration with an iron(III)porphyrin as NADH-oxidase mimic in the enzymatic oxidation of L-glutamate to alpha-ketoglutarate”, Journal of Molecular Catalysis B Enzymatic, 2014, 103, 10-15.
    PUB | DOI | WoS
     
  • [22]
    2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2682298
    H. Gröger, and W. Hummel, “Combining the 'two worlds' of chemocatalysis and biocatalysis towards multi-step one-pot processes in aqueous media”, Current opinion in chemical biology, 2014, 19, 171-179.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [21]
    2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2612864
    C. A. Mueller, B. Akkapurathu, T. Winkler, S. Staudt, W. Hummel, H. Gröger, and U. Schwaneberg, “In Vitro Double Oxidation of n-Heptane with Direct Cofactor Regeneration”, Advanced Synthesis & Catalysis, 2013, 355, 1787-1798.
    PUB | DOI | WoS
     
  • [20]
    2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2560792
    S. Staudt, E. Burda, C. Giese, C. A. Müller, J. Marienhagen, U. Schwaneberg, W. Hummel, K. Drauz, and H. Gröger, “Direct Oxidation of Cycloalkanes to Cycloalkanones with Oxygen in Water”, Angewandte Chemie International Edition, 2013, 52, 2359-2363.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [19]
    2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2637130
    G. Rulli, M. Heidlindemann, A. Berkessel, W. Hummel, and H. Gröger, “Towards catalyst compartimentation in combined chemo- and biocatalytic processes: Immobilization of alcohol dehydrogenases for the diastereoselective reduction of a β-hydroxy ketone obtained from an organocatalytic aldol reaction”, Journal of biotechnology, 2013, 168, 271-276.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [18]
    2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2621189
    E. Burda, T. Reß, T. Winkler, C. Giese, X. Kostrov, T. Huber, W. Hummel, and H. Gröger, “Highly Enantioselective Reduction of α-Methylated Nitroalkenes”, Angewandte Chemie (International ed. in English), 2013, 52, 9323-9326.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [17]
    2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2621177
    S. Staudt, U. T. Bornscheuer, U. Menyes, W. Hummel, and H. Gröger, “Direct biocatalytic one-pot-transformation of cyclohexanol with molecular oxygen into ɛ-caprolactone”, Enzyme and microbial technology, 2013, 53, 288-292.
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  • [16]
    2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2471821
    I. Schnapperelle, W. Hummel, and H. Gröger, “Formal Asymmetric Hydration of Non-Activated Alkenes in Aqueous Medium through a "Chemoenzymatic Catalytic System"”, Chemistry - A European Journal, 2012, 18, 1073-1076.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [15]
    2012 | Sammelwerksbeitrag | Veröffentlicht | PUB-ID: 2397781
    W. Hummel, and H. Gröger, in Enzyme Catalysis in Organic Synthesis (Eds.: K. Drauz, H. Gröger, O. May), Wiley-Vch, Weinheim, 2012, p. 1165-1221.
    PUB
     
  • [14]
    2012 | Sammelwerksbeitrag | Veröffentlicht | PUB-ID: 2397699
    H. Gröger, W. Hummel, S. Borchert, and M. Kraußer, in Enzyme Catalysis in Organic Synthesis (Eds.: K. Drauz, H. Gröger, O. May), Wiley-Vch, Weinheim, 2012.
    PUB
     
  • [13]
    2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2445196
    S. Borchert, E. Burda, J. Schatz, W. Hummel, and H. Gröger, “Combination of a Suzuki cross-coupling reaction using a water-soluble palladium catalyst with an asymmetric enzymatic reduction towards a one-pot reaction in aqueous medium at room temperature”, J. Mol. Catal. B: Enzym., 2012, 84, 89-93.
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  • [12]
    2012 | Sammelwerksbeitrag | Veröffentlicht | PUB-ID: 2398903
    H. Gröger, W. Hummel, and R. Metzner, in Synthetic Methods VI – Enzymatic and Semi-Enzymatic (Eds.: E.M. Carreira, H. Yamamoto), Elsevier, Oxford, 2012, p. 181-215.
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  • [11]
    2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2407538
    H. Maid, P. Böhm, S. M. Huber, W. Bauer, W. Hummel, N. Jux, and H. Gröger, “Eisenkatalyse zur In-situ-Regenerierung oxidierter Cofaktoren durch Aktivierung und Reduktion von O2: ein synthetisches Metallporphyrin als biomimetische NAD(P)H-Oxidase”, Angewandte Chemie, 2011, 123, 2445-2448.
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  • [10]
    2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2344721
    H. Maid, P. Boehm, S. M. Huber, W. Bauer, W. Hummel, N. Jux, and H. Gröger, “Iron Catalysis for In Situ Regeneration of Oxidized Cofactors by Activation and Reduction of Molecular Oxygen: A Synthetic Metalloporphyrin as a Biomimetic NAD(P)H Oxidase”, Angewandte Chemie International Edition, 2011, 50, 2397-2400.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [9]
    2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2407610
    G. Rulli, N. Duangdee, K. Baer, W. Hummel, A. Berkessel, and H. Gröger, “Gesteuerte kinetisch oder thermodynamisch kontrollierte Organokatalyse und Anwendung in der chemoenzymatischen Synthese”, Angew. Chem., 2011, 123, 8092-8095.
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  • [8]
    2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2344713
    G. Rulli, N. Duangdee, K. Baer, W. Hummel, A. Berkessel, and H. Gröger, “Direction of Kinetically versus Thermodynamically Controlled Organocatalysis and Its Application in Chemoenzymatic Synthesis”, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2011, 50, 7944-7947.
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  • [7]
    2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2344730
    N. Richter, H. Gröger, and W. Hummel, “Asymmetric reduction of activated alkenes using an enoate reductase from Gluconobacter oxydans”, APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2011, 89, 79-89.
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  • [6]
    2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2344704
    M. Krausser, T. Winkler, N. Richter, S. Dommer, A. Fingerhut, W. Hummel, and H. Gröger, “Combination of C=C Bond Formation by Wittig Reaction and Enzymatic C=C Bond Reduction in a One-Pot Process in Water”, ChemCatChem, 2011, 3, 293-296.
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  • [5]
    2010 | Sammelwerksbeitrag | Veröffentlicht | PUB-ID: 2344784
    A. Weckbecker, H. Gröger, and W. Hummel, in BIOSYSTEMS ENGINEERING I: CREATING SUPERIOR BIOCATALYSTS (Eds.: C. Wittmann, W.R. Krull), Springer Berlin Heidelberg, Berlin, Heidelberg, 2010, p. 195-242.
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  • [4]
    2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2344737
    N. Dückers, K. Baer, S. Simon, H. Gröger, and W. Hummel, “Threonine aldolases-screening, properties and applications in the synthesis of non-proteinogenic beta-hydroxy-alpha-amino acids”, APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2010, 88, 409-424.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [3]
    2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2344778
    E. Burda, W. Bauer, W. Hummel, and H. Gröger, “Enantio- and Diastereoselective Chemoenzymatic Synthesis of C2-Symmetric Biaryl-Containing Diols”, ChemCatChem, 2010, 2, 67-72.
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  • [2]
    2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2344761
    K. Baer, N. Dueckers, W. Hummel, and H. Gröger, “Expanding the Application Range of Aldolases: Novel Asymmetric Syntheses of alpha-Methylated beta-Hydroxy alpha-Amino Acids and beta-Amino Alcohols”, ChemCatChem, 2010, 2, 939-942.
    PUB | DOI | WoS
     
  • [1]
    2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2344772
    A. Neupert, T. Ress, J. Wittmann, W. Hummel, and H. Gröger, “Enantioselective Biocatalytic Reduction of Non-protected Hydroxyacetophenones”, Zeitschrift für Naturforschung. Section B, a journal of chemical sciences, 2010, 65, 337-340.
    PUB | DOI | WoS
     

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