40 Publikationen
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2020 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2949613D. Bakonyi, C. Toelzer, M. Stricker, W. Hummel, K. Niefind, and H. Gröger, “Expanding the Application Range of Microbial Oxidoreductases by an Alcohol Dehydrogenase from Comamonas testosteroni with a Broad Substrate Spectrum and pH Profile”, Catalysts, 2020, 10, : 1281.PUB | PDF | DOI | WoS
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2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2916563D. Bakonyi, and W. Hummel, “Cloning, expression, and biochemical characterization of a novel NADP(+)-dependent 7 alpha-hydroxysteroid dehydrogenase from Clostridium difficile and its application for the oxidation of bile acids”, ENZYME AND MICROBIAL TECHNOLOGY, 2017, 99, 16-24.PUB | DOI | WoS | PubMed | Europe PMC
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2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2909081G. Rulli, N. Duangdee, W. Hummel, A. Berkessel, and H. Gröger, “First Tandem-Type One-Pot Process Combining Asymmetric Organo- and Biocatalytic Reactions in Aqueous Media Exemplified for the Enantioselective and Diastereoselective Synthesis of 1,3-Diols”, EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2017, 2017, 812-817.PUB | DOI | WoS
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2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2909084M. Biermann, D. Bakonyi, W. Hummel, and H. Gröger, “Design of recombinant whole-cell catalysts for double reduction of C=C and C=O bonds in enals and application in the synthesis of Guerbet alcohols as industrial bulk chemicals for lubricants”, GREEN CHEMISTRY, 2017, 19, 405-410.PUB | DOI | WoS
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2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2904890D. Bulut, N. Duangdee, H. Gröger, A. Berkessel, and W. Hummel, “Screening, Molecular Cloning, and Biochemical Characterization of an Alcohol Dehydrogenase from Pichia pastoris Useful for the Kinetic Resolution of a Racemic β-Hydroxy-β-trifluoromethyl Ketone”, Chembiochem, 2016, 17, 1349-1358.PUB | DOI | WoS | PubMed | Europe PMC
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2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2764353R. Metzner, W. Hummel, F. Wetterich, B. Koenig, and H. Gröger, “Integrated Biocatalysis in Multistep Drug Synthesis without Intermediate Isolation: A de Novo Approach toward a Rosuvastatin Key Building Block”, Organic Process Research & Development, 2015, 19, 635-638.PUB | DOI | WoS
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2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2721884S. Schmidt, C. Scherkus, J. Muschiol, U. Menyes, T. Winkler, W. Hummel, H. Gröger, A. Liese, H. - G. Herz, and U. T. Bornscheuer, “An Enzyme Cascade Synthesis of ε-Caprolactone and its Oligomers”, Angewandte Chemie (International ed. in English), 2015, 54, 2784-2787.PUB | DOI | WoS | PubMed | Europe PMC
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2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2729781H. Sato, W. Hummel, and H. Gröger, “Cooperative Catalysis of Noncompatible Catalysts through Compartmentalization: Wacker Oxidation and Enzymatic Reduction in a One-Pot Process in Aqueous Media”, Angewandte Chemie (International ed. in English), 2015, 54, 4488-4492.PUB | DOI | WoS | PubMed | Europe PMC
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2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2759821L. Engels, M. Henze, W. Hummel, and L. Elling, “Enzyme Module Systems for the Synthesis of Uridine 5 '-Diphospho-alpha-D-glucuronic Acid and Non-Sulfated Human Natural Killer Cell-1 (HNK-1) Epitope”, Advanced Synthesis & Catalysis, 2015, 357, 1751-1762.PUB | DOI | WoS
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2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2761249D. Bulut, H. Gröger, and W. Hummel, “Development of a growth-dependent selection system for identification of L-threonine aldolases”, Applied Microbiology and Biotechnology, 2015, 99, 5875-5883.PUB | DOI | WoS | PubMed | Europe PMC
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2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2729792M. Heidlindemann, M. Hammel, U. Scheffler, R. Mahrwald, W. Hummel, A. Berkessel, and H. Gröger, “Chemoenzymatic Synthesis of Vitamin B5-Intermediate (R)-Pantolactone via Combined Asymmetric Organo- and Biocatalysis”, The Journal of Organic Chemistry, 2015, 80, 3387-3396.PUB | DOI | WoS | PubMed | Europe PMC
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2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2677387T. Winkler, H. Gröger, and W. Hummel, “Enantioselective Rearrangement Coupled with Water Addition: Direct Synthesis of Enantiomerically Pure Saturated Carboxylic Acids from a, b- Unsaturated Aldehydes”, ChemCatChem, 2014, 6, 961-964.PUB | DOI | WoS
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2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2708863C. A. Müller, A. Dennig, T. Welters, T. Winkler, A. J. Ruff, W. Hummel, H. Gröger, and U. Schwaneberg, “Whole-cell double oxidation of n-heptane”, Journal of biotechnology, 2014, 191, 196-204.PUB | DOI | WoS | PubMed | Europe PMC
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2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2708851W. Hummel, and H. Gröger, “Strategies for regeneration of nicotinamide coenzymes emphasizing self-sufficient closed-loop recycling systems”, Journal of biotechnology, 2014, 191, 22-31.PUB | DOI | WoS | PubMed | Europe PMC
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2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2690890M. Heidlindemann, G. Rulli, A. Berkessel, W. Hummel, and H. Gröger, “Combination of Asymmetric Organo- and Biocatalytic Reactions in Organic Media Using Immobilized Catalysts in Different Compartments”, ACS Catalysis, 2014, 4, 1099-1103.PUB | DOI | WoS
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2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2681761W. Greschner, C. Lanzerath, T. Reß, K. Tenbrink, S. Borchert, A. Mix, W. Hummel, and H. Gröger, “Artificial cofactor regeneration with an iron(III)porphyrin as NADH-oxidase mimic in the enzymatic oxidation of L-glutamate to alpha-ketoglutarate”, Journal of Molecular Catalysis B Enzymatic, 2014, 103, 10-15.PUB | DOI | WoS
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2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2682298H. Gröger, and W. Hummel, “Combining the 'two worlds' of chemocatalysis and biocatalysis towards multi-step one-pot processes in aqueous media”, Current opinion in chemical biology, 2014, 19, 171-179.PUB | DOI | WoS | PubMed | Europe PMC
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2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2612864C. A. Mueller, B. Akkapurathu, T. Winkler, S. Staudt, W. Hummel, H. Gröger, and U. Schwaneberg, “In Vitro Double Oxidation of n-Heptane with Direct Cofactor Regeneration”, Advanced Synthesis & Catalysis, 2013, 355, 1787-1798.PUB | DOI | WoS
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2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2560792S. Staudt, E. Burda, C. Giese, C. A. Müller, J. Marienhagen, U. Schwaneberg, W. Hummel, K. Drauz, and H. Gröger, “Direct Oxidation of Cycloalkanes to Cycloalkanones with Oxygen in Water”, Angewandte Chemie International Edition, 2013, 52, 2359-2363.PUB | DOI | WoS | PubMed | Europe PMC
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2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2637130G. Rulli, M. Heidlindemann, A. Berkessel, W. Hummel, and H. Gröger, “Towards catalyst compartimentation in combined chemo- and biocatalytic processes: Immobilization of alcohol dehydrogenases for the diastereoselective reduction of a β-hydroxy ketone obtained from an organocatalytic aldol reaction”, Journal of biotechnology, 2013, 168, 271-276.PUB | DOI | WoS | PubMed | Europe PMC
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2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2621189E. Burda, T. Reß, T. Winkler, C. Giese, X. Kostrov, T. Huber, W. Hummel, and H. Gröger, “Highly Enantioselective Reduction of α-Methylated Nitroalkenes”, Angewandte Chemie (International ed. in English), 2013, 52, 9323-9326.PUB | DOI | WoS | PubMed | Europe PMC
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2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2621177S. Staudt, U. T. Bornscheuer, U. Menyes, W. Hummel, and H. Gröger, “Direct biocatalytic one-pot-transformation of cyclohexanol with molecular oxygen into ɛ-caprolactone”, Enzyme and microbial technology, 2013, 53, 288-292.PUB | DOI | WoS | PubMed | Europe PMC
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2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2471821I. Schnapperelle, W. Hummel, and H. Gröger, “Formal Asymmetric Hydration of Non-Activated Alkenes in Aqueous Medium through a "Chemoenzymatic Catalytic System"”, Chemistry - A European Journal, 2012, 18, 1073-1076.PUB | DOI | WoS | PubMed | Europe PMC
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2012 | Sammelwerksbeitrag | Veröffentlicht | PUB-ID: 2397781W. Hummel, and H. Gröger, in Enzyme Catalysis in Organic Synthesis (Eds.: K. Drauz, H. Gröger, O. May), Wiley-Vch, Weinheim, 2012, p. 1165-1221.PUB
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2012 | Sammelwerksbeitrag | Veröffentlicht | PUB-ID: 2397699H. Gröger, W. Hummel, S. Borchert, and M. Kraußer, in Enzyme Catalysis in Organic Synthesis (Eds.: K. Drauz, H. Gröger, O. May), Wiley-Vch, Weinheim, 2012.PUB
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2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2445196S. Borchert, E. Burda, J. Schatz, W. Hummel, and H. Gröger, “Combination of a Suzuki cross-coupling reaction using a water-soluble palladium catalyst with an asymmetric enzymatic reduction towards a one-pot reaction in aqueous medium at room temperature”, J. Mol. Catal. B: Enzym., 2012, 84, 89-93.PUB | DOI | WoS
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2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2407538H. Maid, P. Böhm, S. M. Huber, W. Bauer, W. Hummel, N. Jux, and H. Gröger, “Eisenkatalyse zur In-situ-Regenerierung oxidierter Cofaktoren durch Aktivierung und Reduktion von O2: ein synthetisches Metallporphyrin als biomimetische NAD(P)H-Oxidase”, Angewandte Chemie, 2011, 123, 2445-2448.PUB | DOI
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2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2344721H. Maid, P. Boehm, S. M. Huber, W. Bauer, W. Hummel, N. Jux, and H. Gröger, “Iron Catalysis for In Situ Regeneration of Oxidized Cofactors by Activation and Reduction of Molecular Oxygen: A Synthetic Metalloporphyrin as a Biomimetic NAD(P)H Oxidase”, Angewandte Chemie International Edition, 2011, 50, 2397-2400.PUB | DOI | WoS | PubMed | Europe PMC
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2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2407610G. Rulli, N. Duangdee, K. Baer, W. Hummel, A. Berkessel, and H. Gröger, “Gesteuerte kinetisch oder thermodynamisch kontrollierte Organokatalyse und Anwendung in der chemoenzymatischen Synthese”, Angew. Chem., 2011, 123, 8092-8095.PUB | DOI
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2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2344713G. Rulli, N. Duangdee, K. Baer, W. Hummel, A. Berkessel, and H. Gröger, “Direction of Kinetically versus Thermodynamically Controlled Organocatalysis and Its Application in Chemoenzymatic Synthesis”, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2011, 50, 7944-7947.PUB | DOI | WoS | PubMed | Europe PMC
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2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2344730N. Richter, H. Gröger, and W. Hummel, “Asymmetric reduction of activated alkenes using an enoate reductase from Gluconobacter oxydans”, APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2011, 89, 79-89.PUB | DOI | WoS | PubMed | Europe PMC
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2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2344704M. Krausser, T. Winkler, N. Richter, S. Dommer, A. Fingerhut, W. Hummel, and H. Gröger, “Combination of C=C Bond Formation by Wittig Reaction and Enzymatic C=C Bond Reduction in a One-Pot Process in Water”, ChemCatChem, 2011, 3, 293-296.PUB | DOI | WoS
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2010 | Sammelwerksbeitrag | Veröffentlicht | PUB-ID: 2344784A. Weckbecker, H. Gröger, and W. Hummel, in BIOSYSTEMS ENGINEERING I: CREATING SUPERIOR BIOCATALYSTS (Eds.: C. Wittmann, W.R. Krull), Springer Berlin Heidelberg, Berlin, Heidelberg, 2010, p. 195-242.PUB | DOI | WoS | PubMed | Europe PMC
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2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2344737N. Dückers, K. Baer, S. Simon, H. Gröger, and W. Hummel, “Threonine aldolases-screening, properties and applications in the synthesis of non-proteinogenic beta-hydroxy-alpha-amino acids”, APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2010, 88, 409-424.PUB | DOI | WoS | PubMed | Europe PMC
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2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2344761K. Baer, N. Dueckers, W. Hummel, and H. Gröger, “Expanding the Application Range of Aldolases: Novel Asymmetric Syntheses of alpha-Methylated beta-Hydroxy alpha-Amino Acids and beta-Amino Alcohols”, ChemCatChem, 2010, 2, 939-942.PUB | DOI | WoS
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2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2344772A. Neupert, T. Ress, J. Wittmann, W. Hummel, and H. Gröger, “Enantioselective Biocatalytic Reduction of Non-protected Hydroxyacetophenones”, Zeitschrift für Naturforschung. Section B, a journal of chemical sciences, 2010, 65, 337-340.PUB | DOI | WoS