PUB - Publikationen an der Universität Bielefeld

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• [56]
  

  2022 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2969198

  T. Stoeger, et al., “Aging is associated with a systemic length-associated transcriptome imbalance”, Nature Aging, vol. 2, 2022, pp. 1191-1206.

  PUB | DOI | WoS
   
• [55]
  

  2021 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2959493

  S. Donkervoort, et al., “BET1 variants establish impaired vesicular transport as a cause for muscular dystrophy with epilepsy”, EMBO Molecular Medicine , 2021, : e13787.

  PUB | PDF | DOI | WoS | PubMed | Europe PMC
   
• [54]
  

  2020 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2948754

  A. Saminathan, et al., “A DNA-based voltmeter for organelles”, Nature Nanotechnology, 2020.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [53]
  

  2019 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2936923

  S. Heybrock, et al., “Lysosomal integral membrane protein-2 (LIMP-2/SCARB2) is involved in lysosomal cholesterol export”, Nature Communications, vol. 10, 2019, : 3521.

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• [52]
  

  2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2931407

  A. Strigli, et al., “Doxorubicin induces caspase-mediated proteolysis of KV7.1”, Communications Biology, vol. 1, 2018, : 155.

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• [51]
  

  2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2932410

  S. Donkervoort, et al., “Recessive mutations in BET1 and GOSR2 establish Q-SNARE Golgi-vesicle-transport genes as a cause for congenital muscular dystrophy with epilepsy”, NEUROMUSCULAR DISORDERS, vol. 28, 2018, : S30.

  PUB | DOI | WoS
   
• [50]
  

  2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953333

  K.S. Conrad, et al., “Lysosomal integral membrane protein-2 as a phospholipid receptor revealed by biophysical and cellular studies”, Nature Communications, vol. 8, 2017, : 1908.

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• [49]
  

  2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953334

  C. Valdez, et al., “Progranulin-mediated deficiency of cathepsin D results in FTD and NCL-like phenotypes in neurons derived from FTD patients”, Human Molecular Genetics, vol. 26, 2017, pp. 4861-4872.

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• [48]
  

  2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2916109

  M.A. Rujano, et al., “Mutations in the X-linked ATP6AP2 cause a glycosylation disorder with autophagic defects”, JOURNAL OF EXPERIMENTAL MEDICINE, vol. 214, 2017, pp. 3707-3729.

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• [47]
  

  2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2916411

  J.M. Völker, et al., “Functional assays for the assessment of the pathogenicity of variants of GOSR2, an ER-to-Golgi SNARE involved in progressive myoclonus epilepsies”, DISEASE MODELS & MECHANISMS, vol. 10, 2017, pp. 1391-1398.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [46]
  

  2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953335

  J. Zheng, et al., “Design and Synthesis of Potent Quinazolines as Selective β-Glucocerebrosidase Modulators”, Journal of Medicinal Chemistry, vol. 59, 2016, pp. 8508-8520.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [45]
  

  2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2913169

  L. Dibbens, et al., “SCARB2/LIMP2 deficiency in action myoclonus-renal failure syndrome”, EPILEPTIC DISORDERS, vol. 18, 2016, pp. S63-S72.

  PUB | DOI | WoS
   
• [44]
  

  2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2903027

  F. Zunke, et al., “Characterization of the complex formed by beta-glucocerebrosidase and the lysosomal integral membrane protein type-2”, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 113, 2016, pp. 3791-3796.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [43]
  

  2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2904109

  S. Kook, et al., “Impaired Lysosomal Integral Membrane Protein 2-dependent Peroxiredoxin 6 Delivery to Lamellar Bodies Accounts for Altered Alveolar Phospholipid Content in Adaptor Protein-3-deficient pearl Mice”, JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 291, 2016, pp. 8414-8427.

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• [42]
  

  2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2901299

  M. Agsten, et al., “BACE1 modulates gating of KCNQ1 (Kv7.1) and cardiac delayed rectifier KCNQ1/KCNE1 (I-Ks)”, Journal of Molecular and Cellular Cardiology, vol. 89, 2015, pp. 335-348.

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• [41]
  

  2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2731234

  S. Hessler, et al., “beta-Secretase BACE1 Regulates Hippocampal and Reconstituted M-Currents in a beta-Subunit-Like Fashion”, Journal of Neuroscience, vol. 35, 2015, pp. 3298-3311.

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• [40]
  

  2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2731248

  J. Peters, et al., “Lysosomal integral membrane protein type-2 (LIMP-2/SCARB2) is a substrate of cathepsin-F, a cysteine protease mutated in type-B-Kufs-disease”, Biochemical and Biophysical Research Communications, vol. 457, 2015, pp. 334-340.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [39]
  

  2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2901039

  J. Blanz, et al., “Mannose 6-phosphate-independent Lysosomal Sorting of Limp-2”, Traffic, vol. 16, 2015, pp. 1127-1136.

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• [38]
  

  2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2759802

  S. Kissing, et al., “Vacuolar ATPase in Phagosome-Lysosome Fusion”, Journal of Biological Chemistry, vol. 290, 2015, pp. 14166-14180.

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• [37]
  

  2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2671368

  J.R. Lemke, et al., “GRIN2B Mutations in West Syndrome and Intellectual Disability with Focal Epilepsy”, Annals of Neurology, vol. 75, 2014, pp. 147-154.

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• [36]
  

  2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2660866

  P. Gaspar, et al., “Action myoclonus-renal failure syndrome: diagnostic applications of activity-based probes and lipid analysis”, The Journal of Lipid Research, vol. 55, 2014, pp. 138-145.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [35]
  

  2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2694992

  A. Rosendahl, et al., “Increased expression of (pro)renin receptor does not cause hypertension or cardiac and renal fibrosis in mice”, Laboratory Investigation, vol. 94, 2014, pp. 863-872.

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• [34]
  

  2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2707698

  M. Rothaug, et al., “LIMP-2 expression is critical for beta-glucocerebrosidase activity and alpha-synuclein clearance”, Proceedings of the National Academy of Sciences, vol. 111, 2014, pp. 15573-15578.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [33]
  

  2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2681867

  J. Schwarz, et al., “Polo-like Kinase 2, a Novel ADAM17 Signaling Component, Regulates Tumor Necrosis Factor similar to Ectodomain Shedding”, Journal of Biological Chemistry, vol. 289, 2014, pp. 3080-3093.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [32]
  

  2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953336

  K.R. Smith, et al., “Cathepsin F mutations cause Type B Kufs disease, an adult-onset neuronal ceroid lipofuscinosis”, Human Molecular Genetics, vol. 22, 2013, pp. 1417-1423.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [31]
  

  2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953337

  M. Schwake, B. Schröder, and P. Saftig, “Lysosomal Membrane Proteins and Their Central Role in Physiology”, Traffic, vol. 14, 2013, pp. 739-748.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [30]
  

  2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953338

  J. Schmid, et al., “Parallel regulation of renin and lysosomal integral membrane protein 2 in renin-producing cells: further evidence for a lysosomal nature of renin secretory vesicles”, Pflügers Archiv - European Journal of Physiology, vol. 465, 2013, pp. 895-905.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [29]
  

  2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953339

  A. Boehlen, et al., “The new KCNQ2 activator 4-Chlor-N-(6-chlor-pyridin-3-yl)-benzamid displays anticonvulsant potential”, British Journal of Pharmacology, vol. 168, 2013, pp. 1182-1200.

  PUB | DOI | Download (ext.) | WoS | PubMed | Europe PMC
   
• [28]
  

  2013 | Sammelwerksbeitrag | Veröffentlicht | PUB-ID: 2953341

  M. Schwake and P. Saftig, “Lysosomal Membrane Defects”, Lysosomal Storage Disorders. A Practical Guide, A. Mehta and B. Winchester, eds., Oxford: Wiley-Blackwell, 2013, pp.131-136.

  PUB | DOI | Download (ext.)
   
• [27]
  

  2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2625613

  J.R. Lemke, et al., “Mutations in GRIN2A cause idiopathic focal epilepsy with rolandic spikes”, Nature Genetics, vol. 45, 2013, pp. 1067-1072.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [26]
  

  2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2645175

  D. Neculai, et al., “Structure of LIMP-2 provides functional insights with implications for SR-BI and CD36”, Nature, vol. 504, 2013, pp. 172-176.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [25]
  

  2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953340

  C. Zachos, et al., “A Critical Histidine Residue Within LIMP-2 Mediates pH Sensitive Binding to Its Ligand β-Glucocerebrosidase”, Traffic, vol. 13, 2012, pp. 1113-1123.

  PUB | DOI | Download (ext.) | WoS | PubMed | Europe PMC
   
• [24]
  

  2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953342

  P.S. Chadha, et al., “Pharmacological dissection of Kv7.1 channels in systemic and pulmonary arteries”, British Journal of Pharmacology, vol. 166, 2012, pp. 1377-1387.

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• [23]
  

  2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953343

  J. Prox, et al., “Tetraspanin15 regulates cellular trafficking and activity of the ectodomain sheddase ADAM10”, Cellular and Molecular Life Sciences, vol. 69, 2012, pp. 2919-2932.

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• [22]
  

  2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953344

  M.A. Corbett, et al., “A Mutation in the Golgi Qb-SNARE Gene GOSR2 Causes Progressive Myoclonus Epilepsy with Early Ataxia”, The American Journal of Human Genetics, vol. 88, 2011, pp. 657-663.

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• [21]
  

  2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953345

  C. Valkova, et al., “Sorting receptor Rer1 controls surface expression of muscle acetylcholine receptors by ER retention of unassembled α-subunits”, Proceedings of the National Academy of Sciences, vol. 108, 2011, pp. 621-625.

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• [20]
  

  2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953346

  M.J. Desmond, et al., “Tubular proteinuria in mice and humans lacking the intrinsic lysosomal protein SCARB2/Limp-2”, American Journal of Physiology-Renal Physiology, vol. 300, 2011, pp. F1437-F1447.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [19]
  

  2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953347

  J. Blanz, et al., “Disease-causing mutations within the lysosomal integral membrane protein type 2 (LIMP-2) reveal the nature of binding to its ligand β-glucocerebrosidase”, Human Molecular Genetics, vol. 19, 2010, pp. 563-572.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [18]
  

  2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953348

  W. Lange, et al., “Refinement of the Binding Site and Mode of Action of the Anticonvulsant Retigabine on KCNQ K Channels”, Molecular Pharmacology, vol. 75, 2009, pp. 272-280.

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• [17]
  

  2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953349

  S.Y.M. Yeung, et al., “Bimodal effects of the K 7 channel activator retigabine on vascular K+ currents”, British Journal of Pharmacology, vol. 155, 2008, pp. 62-72.

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• [16]
  

  2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953350

  S.Y.M. Yeung, et al., “Expression profile and characterisation of a truncated KCNQ5 splice variant”, Biochemical and Biophysical Research Communications, vol. 371, 2008, pp. 741-746.

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• [15]
  

  2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953351

  R. Yamasaki, et al., “Involvement of lysosomal storage-induced p38 MAP kinase activation in the overproduction of nitric oxide by microglia in cathepsin D-deficient mice”, Molecular and Cellular Neuroscience, vol. 35, 2007, pp. 573-584.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [14]
  

  2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953352

  D. Reczek, et al., “LIMP-2 Is a Receptor for Lysosomal Mannose-6-Phosphate-Independent Targeting of β-Glucocerebrosidase”, Cell, vol. 131, 2007, pp. 770-783.

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• [13]
  

  2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953353

  B. Schroen, et al., “Lysosomal integral membrane protein 2 is a novel component of the cardiac intercalated disc and vital for load-induced cardiac myocyte hypertrophy”, Journal of Experimental Medicine, vol. 204, 2007, pp. 1227-1235.

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• [12]
  

  2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953354

  C. Wehling, et al., “Self-assembly of the isolated KCNQ2 subunit interaction domain”, FEBS Letters, vol. 581, 2007, pp. 1594-1598.

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• [11]
  

  2006 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953358

  M. Schwake, “Structural Determinants of M-Type KCNQ (Kv7) K+ Channel Assembly”, Journal of Neuroscience, vol. 26, 2006, pp. 3757-3766.

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• [10]
  

  2006 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953355

  M. Knipper, et al., “Deafness in LIMP2-deficient mice due to early loss of the potassium channel KCNQ1/KCNE1 in marginal cells of the stria vascularis”, The Journal of Physiology, vol. 576, 2006, pp. 73-86.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [9]
  

  2006 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953356

  K. Caeyenberghs, et al., “Multivariate neurocognitive and emotional profile of a mannosidosis murine model for therapy assessment”, Neurobiology of Disease, vol. 23, 2006, pp. 422-432.

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• [8]
  

  2006 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953357

  A. Pachnio, et al., “Proliferation-based T-cell selection for immunotherapy and graft-versus-host-disease prophylaxis in the context of bone marrow transplantation”, Bone Marrow Transplantation, vol. 38, 2006, pp. 157-167.

  PUB | DOI | WoS | PubMed | Europe PMC
   
• [7]
  

  2005 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953361

  D. Dominguez, et al., “Phenotypic and Biochemical Analyses of BACE1- and BACE2-deficient Mice”, Journal of Biological Chemistry, vol. 280, 2005, pp. 30797-30806.

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• [6]
  

  2005 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953360

  R. D'Hooge, et al., “Neurocognitive and Psychotiform Behavioral Alterations and Enhanced Hippocampal Long-Term Potentiation in Transgenic Mice Displaying Neuropathological Features of Human  α-Mannosidosis”, Journal of Neuroscience, vol. 25, 2005, pp. 6539-6549.

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• [5]
  

  2005 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953359

  A. Schenzer, et al., “Molecular Determinants of KCNQ (Kv7) K+ Channel Sensitivity to the Anticonvulsant Retigabine”, Journal of Neuroscience, vol. 25, 2005, pp. 5051-5060.

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• [4]
  

  2003 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953362

  M. Schwake, T.J. Jentsch, and T. Friedrich, “A carboxy‐terminal domain determines the subunit specificity of KCNQ K+ channel assembly”, EMBO reports, vol. 4, 2003, pp. 76-81.

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• [3]
  

  2001 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953363

  M. Schwake, T. Friedrich, and T.J. Jentsch, “An Internalization Signal in ClC-5, an Endosomal Cl−Channel Mutated in Dent's Disease”, Journal of Biological Chemistry, vol. 276, 2001, pp. 12049-12054.

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• [2]
  

  2000 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953364

  N. Piwon, et al., “ClC-5 Cl--channel disruption impairs endocytosis in a mouse model for Dent's disease”, Nature, vol. 408, 2000, pp. 369-373.

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• [1]
  

  2000 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953365

  M. Schwake, et al., “Surface Expression and Single Channel Properties of KCNQ2/KCNQ3, M-type K+ Channels Involved in Epilepsy”, Journal of Biological Chemistry, vol. 275, 2000, pp. 13343-13348.

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