56 Publikationen
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2022 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2969198Stoeger, T., Grant, R.A., McQuattie-Pimentel, A.C., Anekalla, K.R., Liu, S.S., Tejedor-Navarro, H., Singer, B.D., Abdala-Valencia, H., Schwake, M., Tetreault, M.-P., Perlman, H., Balch, W.E., Chandel, N.S., Ridge, K.M., Sznajder, J.I., Morimoto, R.I., Misharin, A.V., Budinger, G.R.S. & Amaral, L.A.N. (2022). Aging is associated with a systemic length-associated transcriptome imbalance. Nature Aging, 2(12), 1191-1206. Nature Research. doi:10.1038/s43587-022-00317-6.
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2021 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2959493Donkervoort, S., Krause, N., Dergai, M., Yun, P., Koliwer, J., Gorokhova, S., Hauserman, J.G., Cummings, B.B., Hu, Y., Smith, R., Uapinyoying, P., Ganesh, V.S., Ghosh, P.S., Monaghan, K.G., Edassery, S.L., Ferle, P., Silverstein, S., Chao, K.R., Snyder, M., Ellingwood, S., Bharucha-Goebel, D., Iannaccone, S.T., Dal Peraro, M., Foley, A.R., Savas, J.N., Bolduc, V., Fasshauer, D., Bonnemann, C.G. & Schwake, M. (2021). BET1 variants establish impaired vesicular transport as a cause for muscular dystrophy with epilepsy. EMBO Molecular Medicine : e13787. Wiley. doi:10.15252/emmm.202013787.
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2020 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2948754Saminathan, A., Devany, J., Veetil, A.T., Suresh, B., Pillai, K.S., Schwake, M. & Krishnan, Y. (2020). A DNA-based voltmeter for organelles. Nature Nanotechnology. Nature Publishing Group. doi:10.1038/s41565-020-00784-1.
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2019 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2936923Heybrock, S., Kanerva, K., Meng, Y., Ing, C., Liang, A., Xiong, Z.-J., Weng, X., Kim, Y.A., Collins, R., Trimble, W., Pomes, R., Prive, G.G., Annaert, W., Schwake, M., Heeren, J., Luellmann-Rauch, R., Grinstein, S., Ikonen, E., Saftig, P. & Neculai, D. (2019). Lysosomal integral membrane protein-2 (LIMP-2/SCARB2) is involved in lysosomal cholesterol export. Nature Communications, 10(1): 3521. Nature Publishing Group. doi:10.1038/s41467-019-11425-0.
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2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2931407Strigli, A., Raab, C., Hessler, S., Huth, T., Schuldt, A.J.T., Alzheimer, C., Friedrich, T., Burridge, P.W., Luedde, M. & Schwake, M. (2018). Doxorubicin induces caspase-mediated proteolysis of KV7.1. Communications Biology, 1(1): 155. Springer Nature . doi:10.1038/s42003-018-0162-z.
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2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2932410Donkervoort, S., Hu, Y., Shieh, P., Koliwer, J., Tsai, L., Cummings, B., Snyder, M., Chao, K., Kaur, R., Bharucha-Goebel, D., Iannaccone, S., MacArthur, D., Foley, A.R., Schwake, M. & Bonnemann, C. (2018). Recessive mutations in BET1 and GOSR2 establish Q-SNARE Golgi-vesicle-transport genes as a cause for congenital muscular dystrophy with epilepsy. NEUROMUSCULAR DISORDERS, 28(Suppl. 2): S30. Gehalten auf der 23rd International Annual Congress of the World-Muscle-Society (WMS), Elsevier. doi:10.1016/j.nmd.2018.06.024.
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2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953333Conrad, K.S., Cheng, T.-W., Ysselstein, D., Heybrock, S., Hoth, L.R., Chrunyk, B.A., am Ende, C.W., Krainc, D., Schwake, M., Saftig, P., Liu, S., Qiu, X. & Ehlers, M.D. (2017). Lysosomal integral membrane protein-2 as a phospholipid receptor revealed by biophysical and cellular studies. Nature Communications, 8(1): 1908. Springer Science and Business Media LLC. doi:10.1038/s41467-017-02044-8.
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2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953334Valdez, C., Wong, Y.C., Schwake, M., Bu, G., Wszolek, Z.K. & Krainc, D. (2017). Progranulin-mediated deficiency of cathepsin D results in FTD and NCL-like phenotypes in neurons derived from FTD patients. Human Molecular Genetics, 26(24), 4861-4872. Oxford University Press (OUP). doi:10.1093/hmg/ddx364.
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2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2916109Rujano, M.A., Serio, M.C., Panasyuk, G., P, R.A., Reunert, J., Rymen, D., Hauser, V., Park, J.H., Freisinger, P., Souche, E., Guida, M.C., Maier, E.M., Wada, Y., Jager, S., Krogan, N.J., Kretz, O., Nobre, S., Garcia, P., Quelhas, D., Bird, T.D., Raskind, W.H., Schwake, M., Duvet, S., Foulquier, F., Matthijs, G., Marquardt, T. & Simons, M. (2017). Mutations in the X-linked ATP6AP2 cause a glycosylation disorder with autophagic defects. JOURNAL OF EXPERIMENTAL MEDICINE, 214(12), 3707-3729. Rockefeller Univ Press. doi:10.1084/jem.20170453.
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2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2916411Völker, J.M., Dergai, M., Abriata, L.A., Mingard, Y., Ysselstein, D., Krainc, D., Dal Peraro, M., Fischer von Mollard, G., Fasshauer, D., Koliwer, J. & Schwake, M. (2017). Functional assays for the assessment of the pathogenicity of variants of GOSR2, an ER-to-Golgi SNARE involved in progressive myoclonus epilepsies. DISEASE MODELS & MECHANISMS, 10(12), 1391-1398. Company Of Biologists Ltd. doi:10.1242/dmm.029132.
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2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953335Zheng, J., Chen, L., Schwake, M., Silverman, R.B. & Krainc, D. (2016). Design and Synthesis of Potent Quinazolines as Selective β-Glucocerebrosidase Modulators. Journal of Medicinal Chemistry, 59(18), 8508-8520. American Chemical Society (ACS). doi:10.1021/acs.jmedchem.6b00930.
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2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2903027Zunke, F., Andresen, L., Wesseler, S., Groth, J., Arnold, P., Rothaug, M., Mazzulli, J.R., Krainc, D., Blanz, J., Saftig, P. & Schwake, M. (2016). Characterization of the complex formed by beta-glucocerebrosidase and the lysosomal integral membrane protein type-2. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 113(14), 3791-3796. Natl Acad Sciences. doi:10.1073/pnas.1514005113.
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2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2904109Kook, S., Wang, P., Young, L.R., Schwake, M., Saftig, P., Weng, X., Meng, Y., Neculai, D., Marks, M.S., Gonzales, L., Beers, M.F. & Guttentag, S. (2016). Impaired Lysosomal Integral Membrane Protein 2-dependent Peroxiredoxin 6 Delivery to Lamellar Bodies Accounts for Altered Alveolar Phospholipid Content in Adaptor Protein-3-deficient pearl Mice. JOURNAL OF BIOLOGICAL CHEMISTRY, 291(16), 8414-8427. Amer Soc Biochemistry Molecular Biology Inc. doi:10.1074/jbc.M116.720201.
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2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2901299Agsten, M., Hessler, S., Lehnert, S., Volk, T., Rittger, A., Hartmann, S., Raab, C., Kim, D.Y., Groemer, T.W., Schwake, M., Alzheimer, C. & Huth, T. (2015). BACE1 modulates gating of KCNQ1 (Kv7.1) and cardiac delayed rectifier KCNQ1/KCNE1 (I-Ks). Journal of Molecular and Cellular Cardiology, 89(pt b), 335-348. Academic Press Ltd - Elsevier Science Ltd. doi:10.1016/j.yjmcc.2015.10.006.
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2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2731234Hessler, S., Zheng, F., Hartmann, S., Rittger, A., Lehnert, S., Voelkel, M., Nissen, M., Edelmann, E., Saftig, P., Schwake, M., Huth, T. & Alzheimer, C. (2015). beta-Secretase BACE1 Regulates Hippocampal and Reconstituted M-Currents in a beta-Subunit-Like Fashion. Journal of Neuroscience, 35(8), 3298-3311. Society For Neuroscience. doi:10.1523/JNEUROSCI.3127-14.2015.
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2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2731248Peters, J., Rittger, A., Weisner, R., Knabbe, J., Zunke, F., Rothaug, M., Damme, M., Berkovic, S.F., Blanz, J., Saftig, P. & Schwake, M. (2015). Lysosomal integral membrane protein type-2 (LIMP-2/SCARB2) is a substrate of cathepsin-F, a cysteine protease mutated in type-B-Kufs-disease. Biochemical and Biophysical Research Communications, 457(3), 334-340. Elsevier. doi:10.1016/j.bbrc.2014.12.111.
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2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2901039Blanz, J., Zunke, F., Markmann, S., Damme, M., Braulke, T., Saftig, P. & Schwake, M. (2015). Mannose 6-phosphate-independent Lysosomal Sorting of Limp-2. Traffic, 16(10), 1127-1136. Wiley-Blackwell. doi:10.1111/tra.12313.
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2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2759802Kissing, S., Hermsen, C., Repnik, U., Nesset, C.K., von Bargen, K., Griffiths, G., Ichihara, A., Lee, B.S., Schwake, M., De Brabander, J., Haas, A. & Saftig, P. (2015). Vacuolar ATPase in Phagosome-Lysosome Fusion. Journal of Biological Chemistry, 290(22), 14166-14180. American Society For Biochemistry And Molecular Biology. doi:10.1074/jbc.M114.628891.
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2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2671368Lemke, J.R., Hendrickx, R., Geider, K., Laube, B., Schwake, M., Harvey, R.J., James, V.M., Pepler, A., Steiner, I., Hoertnagel, K., Neidhardt, J., Ruf, S., Wolff, M., Bartholdi, D., Caraballo, R., Platzer, K., Suls, A., De Jonghe, P., Biskup, S. & Weckhuysen, S. (2014). GRIN2B Mutations in West Syndrome and Intellectual Disability with Focal Epilepsy. Annals of Neurology, 75(1), 147-154. Wiley-Blackwell. doi:10.1002/ana.24073.
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2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2660866Gaspar, P., Kallemeijn, W.W., Strijland, A., Scheij, S., Van Eijk, M., Aten, J., Overkleeft, H.S., Balreira, A., Zunke, F., Schwake, M., Miranda, C.S. & Aerts, J.M.F.G. (2014). Action myoclonus-renal failure syndrome: diagnostic applications of activity-based probes and lipid analysis. The Journal of Lipid Research, 55(1), 138-145. American Society for Biochemistry & Molecular Biology (ASBMB). doi:10.1194/jlr.M043802.
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2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2694992Rosendahl, A., Niemann, G., Lange, S., Ahadzadeh, E., Krebs, C., Contrepas, A., van Goor, H., Wiech, T., Bader, M., Schwake, M., Peters, J., Stahl, R., Nguyen, G. & Wenzel, U. (2014). Increased expression of (pro)renin receptor does not cause hypertension or cardiac and renal fibrosis in mice. Laboratory Investigation, 94(8), 863-872. Nature Publishing Group. doi:10.1038/labinvest.2014.83.
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2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2707698Rothaug, M., Zunke, F., Mazzulli, J.R., Schweizer, M., Altmeppen, H., Luellmann-Rauch, R., Kallemeijn, W.W., Gaspar, P., Aerts, J.M., Glatzel, M., Saftig, P., Krainc, D., Schwake, M. & Blanz, J. (2014). LIMP-2 expression is critical for beta-glucocerebrosidase activity and alpha-synuclein clearance. Proceedings of the National Academy of Sciences, 111(43), 15573-15578. Proceedings of the National Academy of Sciences. doi:10.1073/pnas.1405700111.
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2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2681867Schwarz, J., Schmidt, S., Will, O., Koudelka, T., Koehler, K., Boss, M., Rabe, B., Tholey, A., Scheller, J., Schmidt-Arras, D., Schwake, M., Rose-John, S. & Chalaris, A. (2014). Polo-like Kinase 2, a Novel ADAM17 Signaling Component, Regulates Tumor Necrosis Factor similar to Ectodomain Shedding. Journal of Biological Chemistry, 289(5), 3080-3093. American Society for Biochemistry & Molecular Biology (ASBMB). doi:10.1074/jbc.M113.536847.
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2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953336Smith, K.R., Dahl, H.-H.M., Canafoglia, L., Andermann, E., Damiano, J., Morbin, M., Bruni, A.C., Giaccone, G., Cossette, P., Saftig, P., Grotzinger, J., Schwake, M., Andermann, F., Staropoli, J.F., Sims, K.B., Mole, S.E., Franceschetti, S., Alexander, N.A., Cooper, J.D., Chapman, H.A., Carpenter, S., Berkovic, S.F. & Bahlo, M. (2013). Cathepsin F mutations cause Type B Kufs disease, an adult-onset neuronal ceroid lipofuscinosis. Human Molecular Genetics, 22(7), 1417-1423. Oxford University Press (OUP). doi:10.1093/hmg/dds558.
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2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953337Schwake, M., Schröder, B. & Saftig, P. (2013). Lysosomal Membrane Proteins and Their Central Role in Physiology. Traffic, 14(7), 739-748. Wiley. doi:10.1111/tra.12056.
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2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953338Schmid, J., Oelbe, M., Saftig, P., Schwake, M. & Schweda, F. (2013). Parallel regulation of renin and lysosomal integral membrane protein 2 in renin-producing cells: further evidence for a lysosomal nature of renin secretory vesicles. Pflügers Archiv - European Journal of Physiology, 465(6), 895-905. Springer Science and Business Media LLC. doi:10.1007/s00424-012-1192-x.
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2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953339Boehlen, A., Schwake, M., Dost, R., Kunert, A., Fidzinski, P., Heinemann, U. & Gebhardt, C. (2013). The new KCNQ2 activator 4-Chlor-N-(6-chlor-pyridin-3-yl)-benzamid displays anticonvulsant potential. British Journal of Pharmacology, 168(5), 1182-1200. Wiley. doi:10.1111/bph.12065.
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2013 | Sammelwerksbeitrag | Veröffentlicht | PUB-ID: 2953341Schwake, M. & Saftig, P. (2013). Lysosomal Membrane Defects. In A. Mehta & B. Winchester (Hrsg.), Lysosomal Storage Disorders. A Practical Guide (S. 131-136). Oxford: Wiley-Blackwell. doi:10.1002/9781118514672.ch17.
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2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2625613Lemke, J.R., Lal, D., Reinthaler, E.M., Steiner, I., Nothnagel, M., Alber, M., Geider, K., Laube, B., Schwake, M., Finsterwalder, K., Franke, A., Schilhabel, M., Jaehn, J.A., Muhle, H., Boor, R., Van Paesschen, W., Caraballo, R., Fejerman, N., Weckhuysen, S., De Jonghe, P., Larsen, J., Moller, R.S., Hjalgrim, H., Addis, L., Tang, S., Hughes, E., Pal, D.K., Veri, K., Vaher, U., Talvik, T., Dimova, P., Lopez, R.G., Serratosa, J.M., Linnankivi, T., Lehesjoki, A.-E., Ruf, S., Wolff, M., Buerki, S., Wohlrab, G., Kroell, J., Datta, A.N., Fiedler, B., Kurlemann, G., Kluger, G., Hahn, A., Haberlandt, D.E., Kutzer, C., Sperner, J., Becker, F., Weber, Y.G., Feucht, M., Steinboeck, H., Neophythou, B., Ronen, G.M., Gruber-Sedlmayr, U., Geldner, J., Harvey, R.J., Hoffmann, P., Herms, S., Altmueller, J., Toliat, M.R., Thiele, H., Nuernberg, P., Wilhelm, C., Stephani, U., Helbig, I., Lerche, H., Zimprich, F., Neubauer, B.A., Biskup, S. & von Spiczak, S. (2013). Mutations in GRIN2A cause idiopathic focal epilepsy with rolandic spikes. Nature Genetics, 45(9), 1067-1072. Nature Publishing Group. doi:10.1038/ng.2728.
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2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2645175Neculai, D., Schwake, M., Ravichandran, M., Zunke, F., Collins, R.F., Peters, J., Neculai, M., Plumb, J., Loppnau, P., Pizarro, J.C., Seitova, A., Trimble, W.S., Saftig, P., Grinstein, S. & Dhe-Paganon, S. (2013). Structure of LIMP-2 provides functional insights with implications for SR-BI and CD36. Nature, 504(7478), 172-176. Nature Publishing Group. doi:10.1038/nature12684.
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2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953340Zachos, C., Blanz, J., Saftig, P. & Schwake, M. (2012). A Critical Histidine Residue Within LIMP-2 Mediates pH Sensitive Binding to Its Ligand β-Glucocerebrosidase. Traffic, 13(8), 1113-1123. Wiley. doi:10.1111/j.1600-0854.2012.01372.x.
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2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953342Chadha, P.S., Zunke, F., Davis, A.J., Jepps, T.A., Linders, J.T.M., Schwake, M., Towart, R. & Greenwood, I.A. (2012). Pharmacological dissection of Kv7.1 channels in systemic and pulmonary arteries. British Journal of Pharmacology, 166(4), 1377-1387. Wiley. doi:10.1111/j.1476-5381.2012.01863.x.
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2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953343Prox, J., Willenbrock, M., Weber, S., Lehmann, T., Schmidt-Arras, D., Schwanbeck, R., Saftig, P. & Schwake, M. (2012). Tetraspanin15 regulates cellular trafficking and activity of the ectodomain sheddase ADAM10. Cellular and Molecular Life Sciences, 69(17), 2919-2932. Springer Science and Business Media LLC. doi:10.1007/s00018-012-0960-2.
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2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953344Corbett, M.A., Schwake, M., Bahlo, M., Dibbens, L.M., Lin, M., Gandolfo, L.C., Vears, D.F., O'Sullivan, J.D., Robertson, T., Bayly, M.A., Gardner, A.E., Vlaar, A.M., Korenke, G.C., Bloem, B.R., de Coo, I. F., Verhagen, J.M.A., Lehesjoki, A.-E., Gecz, J. & Berkovic, S.F. (2011). A Mutation in the Golgi Qb-SNARE Gene GOSR2 Causes Progressive Myoclonus Epilepsy with Early Ataxia. The American Journal of Human Genetics, 88(5), 657-663. Elsevier BV. doi:10.1016/j.ajhg.2011.04.011.
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2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953345Valkova, C., Albrizio, M., Roder, I.V., Schwake, M., Betto, R., Rudolf, R. & Kaether, C. (2011). Sorting receptor Rer1 controls surface expression of muscle acetylcholine receptors by ER retention of unassembled α-subunits. Proceedings of the National Academy of Sciences, 108(2), 621-625. Proceedings of the National Academy of Sciences. doi:10.1073/pnas.1001624108.
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2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953346Desmond, M.J., Lee, D., Fraser, S.A., Katerelos, M., Gleich, K., Martinello, P., Li, Y.Q., Thomas, M.C., Michelucci, R., Cole, A.J., Saftig, P., Schwake, M., Stapleton, D., Berkovic, S.F. & Power, D.A. (2011). Tubular proteinuria in mice and humans lacking the intrinsic lysosomal protein SCARB2/Limp-2. American Journal of Physiology-Renal Physiology, 300(6), F1437-F1447. American Physiological Society. doi:10.1152/ajprenal.00015.2011.
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2010 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953347Blanz, J., Groth, J., Zachos, C., Wehling, C., Saftig, P. & Schwake, M. (2010). Disease-causing mutations within the lysosomal integral membrane protein type 2 (LIMP-2) reveal the nature of binding to its ligand β-glucocerebrosidase. Human Molecular Genetics, 19(4), 563-572. Oxford University Press (OUP). doi:10.1093/hmg/ddp523.
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2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953348Lange, W., Geißendörfer, J., Schenzer, A., Grötzinger, J., Seebohm, G., Friedrich, T. & Schwake, M. (2009). Refinement of the Binding Site and Mode of Action of the Anticonvulsant Retigabine on KCNQ K Channels. Molecular Pharmacology, 75(2), 272-280. American Society for Pharmacology & Experimental Therapeutics (ASPET). doi:10.1124/mol.108.052282.
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2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953349Yeung, S.Y.M., Schwake, M., Pucovský, V. & Greenwood, I.A. (2008). Bimodal effects of the K 7 channel activator retigabine on vascular K+ currents. British Journal of Pharmacology, 155(1), 62-72. Wiley. doi:10.1038/bjp.2008.231.
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2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953350Yeung, S.Y.M., Lange, W., Schwake, M. & Greenwood, I.A. (2008). Expression profile and characterisation of a truncated KCNQ5 splice variant. Biochemical and Biophysical Research Communications, 371(4), 741-746. Elsevier BV. doi:10.1016/j.bbrc.2008.04.129.
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2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953351Yamasaki, R., Zhang, J., Koshiishi, I., Sastradipura Suniarti, D.F., Wu, Z., Peters, C., Schwake, M., Uchiyama, Y., Kira, J.-ichi, Saftig, P., Utsumi, H. & Nakanishi, H. (2007). Involvement of lysosomal storage-induced p38 MAP kinase activation in the overproduction of nitric oxide by microglia in cathepsin D-deficient mice. Molecular and Cellular Neuroscience, 35(4), 573-584. Elsevier BV. doi:10.1016/j.mcn.2007.05.002.
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2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953352Reczek, D., Schwake, M., Schröder, J., Hughes, H., Blanz, J., Jin, X., Brondyk, W., Van Patten, S., Edmunds, T. & Saftig, P. (2007). LIMP-2 Is a Receptor for Lysosomal Mannose-6-Phosphate-Independent Targeting of β-Glucocerebrosidase. Cell, 131(4), 770-783. Elsevier BV. doi:10.1016/j.cell.2007.10.018.
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2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953353Schroen, B., Leenders, J.J., van Erk, A., Bertrand, A.T., van Loon, M., van Leeuwen, R.E., Kubben, N., Duisters, R.F., Schellings, M.W., Janssen, B.J., Debets, J.J., Schwake, M., Høydal, M.A., Heymans, S., Saftig, P. & Pinto, Y.M. (2007). Lysosomal integral membrane protein 2 is a novel component of the cardiac intercalated disc and vital for load-induced cardiac myocyte hypertrophy. Journal of Experimental Medicine, 204(5), 1227-1235. Rockefeller University Press. doi:10.1084/jem.20070145.
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2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953354Wehling, C., Beimgraben, C., Gelhaus, C., Friedrich, T., Saftig, P., Grötzinger, J. & Schwake, M. (2007). Self-assembly of the isolated KCNQ2 subunit interaction domain. FEBS Letters, 581(8), 1594-1598. Wiley. doi:10.1016/j.febslet.2007.03.024.
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2006 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953358Schwake, M. (2006). Structural Determinants of M-Type KCNQ (Kv7) K+ Channel Assembly. Journal of Neuroscience, 26(14), 3757-3766. Society for Neuroscience. doi:10.1523/JNEUROSCI.5017-05.2006.
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2006 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953355Knipper, M., Claussen, C., Rüttiger, L., Zimmermann, U., Lüllmann-Rauch, R., Eskelinen, E.-L., Schröder, J., Schwake, M. & Saftig, P. (2006). Deafness in LIMP2-deficient mice due to early loss of the potassium channel KCNQ1/KCNE1 in marginal cells of the stria vascularis. The Journal of Physiology, 576(1), 73-86. Wiley. doi:10.1113/jphysiol.2006.116889.
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2006 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953356Caeyenberghs, K., Balschun, D., Roces, D.P., Schwake, M., Saftig, P. & D'Hooge, R. (2006). Multivariate neurocognitive and emotional profile of a mannosidosis murine model for therapy assessment. Neurobiology of Disease, 23(2), 422-432. Elsevier BV. doi:10.1016/j.nbd.2006.03.009.
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2006 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953357Pachnio, A., Dietrich, S., Klapper, W., Humpe, A., Schwake, M., Sedlacek, R., Gramatzki, M. & Beck, C. (2006). Proliferation-based T-cell selection for immunotherapy and graft-versus-host-disease prophylaxis in the context of bone marrow transplantation. Bone Marrow Transplantation, 38(2), 157-167. Springer Science and Business Media LLC. doi:10.1038/sj.bmt.1705411.
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2005 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953361Dominguez, D., Tournoy, J., Hartmann, D., Huth, T., Cryns, K., Deforce, S., Serneels, L., Camacho, I.E., Marjaux, E., Craessaerts, K., Roebroek, A.J.M., Schwake, M., D'Hooge, R., Bach, P., Kalinke, U., Moechars, D., Alzheimer, C., Reiss, K., Saftig, P. & De Strooper, B. (2005). Phenotypic and Biochemical Analyses of BACE1- and BACE2-deficient Mice. Journal of Biological Chemistry, 280(35), 30797-30806. Elsevier BV. doi:10.1074/jbc.M505249200.
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2005 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953360D'Hooge, R., Lüllmann-Rauch, R., Beckers, T., Balschun, D., Schwake, M., Reiss, K., von Figura, K. & Saftig, P. (2005). Neurocognitive and Psychotiform Behavioral Alterations and Enhanced Hippocampal Long-Term Potentiation in Transgenic Mice Displaying Neuropathological Features of Human α-Mannosidosis. Journal of Neuroscience, 25(28), 6539-6549. Society for Neuroscience. doi:10.1523/JNEUROSCI.0283-05.2005.
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2005 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953359Schenzer, A., Friedrich, T., Pusch, M., Saftig, P., Jentsch, T.J., Grötzinger, J. & Schwake, M. (2005). Molecular Determinants of KCNQ (Kv7) K+ Channel Sensitivity to the Anticonvulsant Retigabine. Journal of Neuroscience, 25(20), 5051-5060. Society for Neuroscience. doi:10.1523/JNEUROSCI.0128-05.2005.
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2003 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953362Schwake, M., Jentsch, T.J. & Friedrich, T. (2003). A carboxy‐terminal domain determines the subunit specificity of KCNQ K+ channel assembly. EMBO reports, 4(1), 76-81. EMBO. doi:10.1038/sj.embor.embor715.
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2001 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953363Schwake, M., Friedrich, T. & Jentsch, T.J. (2001). An Internalization Signal in ClC-5, an Endosomal Cl−Channel Mutated in Dent's Disease. Journal of Biological Chemistry, 276(15), 12049-12054. Elsevier BV. doi:10.1074/jbc.M010642200.
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2000 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953364Piwon, N., Günther, W., Schwake, M., Bösl, M.R. & Jentsch, T.J. (2000). ClC-5 Cl--channel disruption impairs endocytosis in a mouse model for Dent's disease. Nature, 408(6810), 369-373. Springer Science and Business Media LLC. doi:10.1038/35042597.
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2000 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2953365Schwake, M., Pusch, M., Kharkovets, T. & Jentsch, T.J. (2000). Surface Expression and Single Channel Properties of KCNQ2/KCNQ3, M-type K+ Channels Involved in Epilepsy. Journal of Biological Chemistry, 275(18), 13343-13348. Elsevier BV. doi:10.1074/jbc.275.18.13343.