52 Publikationen
-
2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2907725Heparin Binds Lamprey Angiotensinogen and Promotes Thrombin Inhibition through a Template MechanismPUB | DOI | WoS | PubMed | Europe PMC
Wei H, Cai H, Wu J, Wei Z, Zhang F, Huang X, Ma L, Feng L, Zhang R, Wang Y, Ragg H, et al. (2016)
JOURNAL OF BIOLOGICAL CHEMISTRY 291(48): 24900-24911. -
2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2690864Repression of liver colorectal metastasis by the serpin Spn4A a naturally occurring inhibitor of the constitutive secretory proprotein convertasesPUB | DOI | WoS | PubMed | Europe PMC
Sfaxi F, Scamuffa N, Lalou C, Ma J, Metrakos P, Siegfried G, Ragg H, Bikfalvi A, Calvo F, Khatib A-M (2014)
Oncotarget 5(12): 4195-4210. -
2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2677460Origin of serpin-mediated regulation of coagulation and blood pressurePUB | PDF | DOI | WoS | PubMed | Europe PMC
Wang Y, Köster K, Lummer M, Ragg H (2014)
PLoS ONE 9(5): e97879. -
2011 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 2423346Angiotensinogen: the multi-faceted nature of an ancient vertebrate serpinPUB
Wang Y, Ragg H (2011)
Presented at the 6th International Symposium on the Chemistry and Biology of Serpins, Raleigh, North Carolina. -
2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2423353Bioinformatic approaches for the identification of serpin genes with multiple reactive site loop coding exonsPUB | DOI | WoS | PubMed | Europe PMC
Börner S, Ragg H (2011)
Methods in Enzymology 501: 209-222. -
2011 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 2423350How control of thrombin by serpins in vertebrates arosePUB
Ragg H, Wang Y (2011)
In: Abstracts of the XXIII Congress of the International Society on Thrombosis and Haemostasis 57th Annual SSC Meeting, July 23-28 2011, Kyoto, Japan. Journal of Thrombosis and Haemostasis, 9(Suppl. 2). Wiley: 723. -
2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1948655 PUB | DOI | WoS | PubMed | Europe PMC
-
2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2307100An unexpected link between angiotensinogen and thrombinPUB | DOI | WoS | PubMed | Europe PMC
Wang Y, Ragg H (2011)
FEBS Letters 585(14): 2395-2399. -
2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1784544Multiple gains of spliceosomal introns in a superfamily of vertebrate protease inhibitor genesPUB | PDF | DOI | WoS | PubMed | Europe PMC
Ragg H, Kumar A, Köster K, Bentele C, Wang Y, Frese M-A, Prib N, Krüger O (2009)
BMC Evolutionary Biology 9(1): 208. -
2008 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 1955161Multitasking serpin genes in the genus Drosophila and beyond: evolution and functional diversificationPUB
Börner S, Ragg H (2008)
Presented at the Serpins 2008, 5th International Symposium on Serpin Biology, Structure and Function, Leuwen, Belgium. -
2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1783341Ancestry and evolution of a secretory pathway serpinPUB | PDF | DOI | WoS | PubMed | Europe PMC
Kumar A, Ragg H (2008)
BMC Evolutionary Biology 8(1): 250. -
2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1587736Functional diversification of a protease inhibitor gene in the genus Drosophila and its molecular basisPUB | DOI | WoS | PubMed | Europe PMC
Börner S, Ragg H (2008)
GENE 415(1-2): 23-31. -
2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1953796The Spn4 gene from Drosophila melanogaster is a multipurpose defense tool directed against proteases from three different peptidase familiesPUB | DOI | WoS | PubMed | Europe PMC
Brüning M, Lummer M, Bentele C, Smolenaars MMW, Rodenburg KW, Ragg H (2007)
Biochem. J. 401(1): 325-331. -
2007 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 1955191Proprotein convertase inhibiting serpins along the secretory pathwayPUB
Bentele C, Oley M, Tödtmann U, Krüger O, Ragg H (2007)
Presented at the Mosbacher Kolloquium der Gesellschaft für Biochemie und Molekularbiologie, Mosbach. -
2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1631413The role of serpins in the surveillance of the secretory pathwayPUB | DOI | WoS | PubMed | Europe PMC
Ragg H (2007)
CELL. MOL. LIFE SCI. 64(21): 2763-2770. -
2006 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1953791A proprotein convertase-inhibiting serpin with an ER targeting signal from Branchiostoma lanceolatum, a close relative of vertebratesPUB | DOI | WoS | PubMed | Europe PMC
Bentele C, Krüger O, Tödtmann U, Oley M, Ragg H (2006)
Biochem. J. 395(3): 449-456. -
2006 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 1955145The role of serpins along the secretory pathway: regulation of prohormone convertases and beyondPUB
Bentele C, Krüger O, Tödtmann U, Oley M, Ragg H (2006)
In: Gordon Research Conferences. -
2005 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 1600740Target identification for Spn4, a gene encoding serpin isoforms with alternative reactive site loopsPUB | WoS
Oley M, Ragg H (2005)
FEBS JOURNAL 272(Suppl. 1): 174-174. -
2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1606208Reformable intramolecular cross-linking of the N-terminal domain of heparin cofactor II - Effects on enzyme inhibitionPUB | DOI | WoS | PubMed | Europe PMC
Brinkmeyer S, Eckert R, Ragg H (2004)
EUROPEAN JOURNAL OF BIOCHEMISTRY 271(21): 4275-4283. -
2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1953787Inhibition of furin by serpin Spn4A from Drosophila melanogasterPUB | DOI | WoS | PubMed | Europe PMC
Oley M, Letzel M, Ragg H (2004)
FEBS Letters 577(1-2): 165-169. -
2003 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1953801Zinc ions promote the interaction between heparin and heparin cofactor IIPUB | DOI | WoS | PubMed | Europe PMC
Eckert R, Ragg H (2003)
FEBS Letters 541(1-3): 121-125. -
2002 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1615250Tyrosine sulfation and N-glycosylation of human heparin cofactor II from plasma and recombinant Chinese hamster ovary cells and their effects on heparin bindingPUB | DOI | WoS | PubMed | Europe PMC
Böhme C, Nimtz M, Grabenhorst E, Conradt HS, Strathmann A, Ragg H (2002)
EUROPEAN JOURNAL OF BIOCHEMISTRY 269(3): 977-988. -
2002 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1613937Widespread occurrence of serpin genes with multiple reactive centre-containing exon cassettes in insects and nematodesPUB | DOI | WoS | PubMed | Europe PMC
Krüger O, Ladewig J, Köster K, Ragg H (2002)
GENE 293(1-2): 97-105. -
2001 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 1955179Evidence for allosteric activation of heparin cofactor II in the presence of heparin or dermatan sulfatePUB
Brinkmeyer S, Eckert R, Ragg H (2001)
Presented at the XVIIIth Congress of the International Society on Thrombosis and Haemostasis, Paris. -
2001 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1616585Phylogenetic analyses of amino acid variation in the serpin proteinsPUB | DOI | WoS | PubMed | Europe PMC
Atchley WR, Lokot T, Wollenberg K, Dress A, Ragg H (2001)
MOLECULAR BIOLOGY AND EVOLUTION 18(8): 1502-1511. -
2001 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1617557Vertebrate serpins: Construction of a conflict-free phylogeny by combining exon-intron and diagnostic site analysesPUB | DOI | WoS | PubMed | Europe PMC
Ragg H, Lokot T, Kamp P-B, Atchley WR, Dress A (2001)
MOLECULAR BIOLOGY AND EVOLUTION 18(4): 577-584. -
2001 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1617446Heparin cofactor II, antithrombin-beta and their complexes with thrombin in human tissuesPUB | DOI | WoS | PubMed | Europe PMC
Kamp P-B, Strathmann A, Ragg H (2001)
THROMBOSIS RESEARCH 101(6): 483-491. -
1999 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1623326Rapid changes in the exon/intron structure of a mammalian thrombin inhibitor genePUB | DOI | WoS | PubMed | Europe PMC
Kamp P-B, Ragg H (1999)
GENE 229(1-2): 137-144. -
1997 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1954263Enhanced specificity of minimally modified anti-c-myc oligonucleotidesPUB
Peyman A, Ragg H, Ulshöfer T, Will DW, Uhlmann E (1997)
Nucleosides & Nucleotides 16: 1215-1219. -
1994 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1953772Secondary thrombin-binding site, glycosaminoglycan binding domain and reactive center region of leuserpin-2 are strongly conserved in mammalian speciesPUB
Westrup D, Ragg H (1994)
Biochim. Biophys. Acta 1217: 93-96. -
1990 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1953759On the activation of human leuserpin-2, a thrombin inhibitor, by glycosaminoglycansPUB
Ragg H, Ulshöfer T, Gerewitz J (1990)
J. Biol. Chem. 265: 5211-5218. -
1990 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1953767Human peptidylglycine alpha-amidating monooxygenase: cDNA cloning and functional expression of a truncated form in COS cellsPUB
Glauder J, Ragg H, Rauch J, Engels JW (1990)
Biochem. Biophys. Res. Commun. 169: 551-558. -
1990 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1953763Glycosaminoglycan-mediated leuserpin-2/thrombin interaction: structure-function relationshipsPUB
Ragg H, Ulshöfer T, Gerewitz J (1990)
J. Biol. Chem. 265: 22386-22301. -
1988 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1948728Structure and expression of the gene coding for the human serpin hLS2PUB
Ragg H, Preibisch G (1988)
J. Biol. Chem. 263: 12129-12134. -
1987 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1948715Expression of human antithrombin III in Saccharomyces cerevisiae and Schizosaccharomyces pombePUB
Bröker M, Ragg H, Karges HE (1987)
Biochim. Biophys. Acta 908: 203-213. -
1987 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1948719Expression of biologically active human antithrombin III in Chinese hamster ovary cellsPUB
Zettlmeissl G, Ragg H, Karges HE (1987)
Bio-Technology 5: 720-725. -
1986 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1948704A new member of the plasma protease inhibitor gene familyPUB
Ragg H (1986)
Nucleic Acids Res. 14: 1073-1088. -
1985 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1948699A 46-nucleotide promotor segment from an IFN-alpha gene renders an unrelated promotor inducible by virusPUB
Ryals J, Dierks P, Ragg H, Weissmann C (1985)
Cell 41: 497-507. -
1983 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1948696Not more than 117 base pairs of 5'-flanking sequence are required for inducible expression of a human IFN-alpha gene.PUB
Ragg H, Weissmann C (1983)
Nature 303: 439-442. -
1983 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 1954275The induced transcription of a human IFN-alpha gene requires not more than 117 base pairs of 5'-flanking sequencePUB
Ragg H, Weidle U, Mantei N, Weissmann C (1983)
Presented at the Second International TNO Meeting on the Biology of the Interferon System, Rotterdam. -
1983 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1948675UV-induction of chalcone synthase mRNA in cell suspension cultures of Petroselinum hortensePUB
Kreuzaler F, Ragg H, Fautz E, Kuhn DN, Hahlbrock K (1983)
Proc. Natl. Acad. Sci. USA 80: 2591-2593. -
1982 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1948687Studies on the chalcone synthase gene of two higher plants: Petroselinum hortense and Matthiola incanaPUB
Hemleben V, Frey M, Rall S, Koch M, Kittel M, Kreuzaler F, Ragg H, Fautz E, Hahlbrock K (1982)
Progr. Clin. Biol. Res. 85 (Pt B): 555-566. -
1982 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1946278A general method to identify plant structural genes among genomic DNA clones using transposable element induced mutationsPUB
Wienand U, Sommer H, Schwarz Z, Shepard N, Saedler H, Kreuzaler F, Ragg H, Fautz E, Hahlbrock K (1982)
Mol. Gen. Genet. 187: 195-201. -
1982 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1948634Structure and expression of human IFN-alpha genesPUB
Weissmann C, Nagata S, Boll W, Fountoulakis M, Fujisawa A, Fujisawa J-I, Haynes J, Henco K, Mantei N, Ragg H, Schein C, et al. (1982)
Philos. Trans. R. Soc. Lond. B 299(1094): 7-28. -
1982 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 1954292Regulation of flavonoid and phytoalexin accumulation through mRNA and enzyme induction in cultured plant cellsPUB
Hahlbrock K, Kreuzaler F, Ragg H, Fautz E, Kuhn DN (1982)
In: 33. Colloquium der Gesellschaft für Biologische Chemie. Jaenicke L (Ed); Berlin: Springer-Verlag: 34-43. -
1981 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1945081Coordinated regulation of 4-coumarate: CoA ligase and phenylalanine ammonia-lyase mRNAs in cultured plant cellsPUB
Ragg H, Kuhn DN, Hahlbrock K (1981)
J. Biol. Chem. 256: 10061-10065. -
1980 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1945070Messenger RNA coding for phenylalanine ammonia-lyase: Characterization and partial purification from cell suspension cultures of Petroselinum hortensePUB
Ragg H, Hahlbrock K (1980)
Eur. J. Biochem. 103: 323-330. -
1979 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1945064Flavanone synthase from Petroselinum hortense: Molecular weight, subunit composition, size of messenger RNA, and absence of panthetheinyl residuePUB
Kreuzaler F, Ragg H, Heller W, Tesch R, Witt I, Hammer D, Hahlbrock K (1979)
Eur. J. Biochem. 99: 89-96. -
1978 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 1954304Enzyme induction in cultured cellsPUB
Hahlbrock K, Betz B, Gardiner SE, Kreuzaler F, Matern U, Ragg H, Schäfer E, Schröder J (1978)
Presented at the Proceedings of the 4th International Congress of Plant Tissue and Cell Culture, Calgary, Alberta, Canada. -
1977 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1945055Translation of poly(A)-containing and poly(A)-free messenger RNA for phenylalanine ammonia-lyase, a plant-specific protein, in a reticulocyte lysatePUB
Ragg H, Schröder J, Hahlbrock K (1977)
Biochim. Biophys. Acta 474: 226-233. -
1975 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1941362Light-induced changes of enzyme activities in parsley suspension cultures: Effects of inhibitors of RNA and protein synthesisPUB
Hahlbrock K, Ragg H (1975)
Arch. Biochem. Biophys. 166: 41-46. -
1975 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1941368Poly(A)-containing RNA from Petroselinum hortense: Isolation, properties and messenger function in vitroPUB
Ragg H, Schröder J, Hahlbrock K (1975)
Molecular Biology Reports 2: 119-127.