52 Publikationen

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  • [52]
    2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2907725
    Wei, H., Cai, H., Wu, J., Wei, Z., Zhang, F., Huang, X., Ma, L., Feng, L., Zhang, R., Wang, Y., et al. (2016). Heparin Binds Lamprey Angiotensinogen and Promotes Thrombin Inhibition through a Template Mechanism. JOURNAL OF BIOLOGICAL CHEMISTRY 291, 24900-24911.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [51]
    2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2690864
    Sfaxi, F., Scamuffa, N., Lalou, C., Ma, J., Metrakos, P., Siegfried, G., Ragg, H., Bikfalvi, A., Calvo, F., and Khatib, A. - M. (2014). Repression of liver colorectal metastasis by the serpin Spn4A a naturally occurring inhibitor of the constitutive secretory proprotein convertases. Oncotarget 5, 4195-4210.
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  • [50]
    2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2677460 OA
    Wang, Y., Köster, K., Lummer, M., and Ragg, H. (2014). Origin of serpin-mediated regulation of coagulation and blood pressure. PLoS ONE 9:e97879.
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  • [49]
    2011 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 2423346
    Wang, Y., and Ragg, H. (2011).“Angiotensinogen: the multi-faceted nature of an ancient vertebrate serpin”. Presented at the 6th International Symposium on the Chemistry and Biology of Serpins, Raleigh, North Carolina.
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  • [48]
    2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2423353
    Börner, S., and Ragg, H. (2011). Bioinformatic approaches for the identification of serpin genes with multiple reactive site loop coding exons. Methods in Enzymology 501, 209-222.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [47]
    2011 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 2423350
    Ragg, H., and Wang, Y. (2011). “How control of thrombin by serpins in vertebrates arose” in Abstracts of the XXIII Congress of the International Society on Thrombosis and Haemostasis 57th Annual SSC Meeting, July 23-28 2011, Kyoto, Japan Journal of Thrombosis and Haemostasis, vol. 9, (Wiley), 723.
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  • [46]
    2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1948655
    Ragg, H. (2011). Intron creation and DNA repair. Cell. Mol. Life Sci. 68, 235-242.
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  • [45]
    2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2307100
    Wang, Y., and Ragg, H. (2011). An unexpected link between angiotensinogen and thrombin. FEBS Letters 585, 2395-2399.
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  • [44]
    2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1784544 OA
    Ragg, H., Kumar, A., Köster, K., Bentele, C., Wang, Y., Frese, M. - A., Prib, N., and Krüger, O. (2009). Multiple gains of spliceosomal introns in a superfamily of vertebrate protease inhibitor genes. BMC Evolutionary Biology 9, 208.
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  • [43]
    2008 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 1955161
    Börner, S., and Ragg, H. (2008).“Multitasking serpin genes in the genus Drosophila and beyond: evolution and functional diversification”. Presented at the Serpins 2008, 5th International Symposium on Serpin Biology, Structure and Function, Leuwen, Belgium.
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  • [42]
    2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1783341 OA
    Kumar, A., and Ragg, H. (2008). Ancestry and evolution of a secretory pathway serpin. BMC Evolutionary Biology 8:250.
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  • [41]
    2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1587736
    Börner, S., and Ragg, H. (2008). Functional diversification of a protease inhibitor gene in the genus Drosophila and its molecular basis. GENE 415, 23-31.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [40]
    2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1953796
    Brüning, M., Lummer, M., Bentele, C., Smolenaars, M. M. W., Rodenburg, K. W., and Ragg, H. (2007). The Spn4 gene from Drosophila melanogaster is a multipurpose defense tool directed against proteases from three different peptidase families. Biochem. J. 401, 325-331.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [39]
    2007 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 1955191
    Bentele, C., Oley, M., Tödtmann, U., Krüger, O., and Ragg, H. (2007).“Proprotein convertase inhibiting serpins along the secretory pathway”. Presented at the Mosbacher Kolloquium der Gesellschaft für Biochemie und Molekularbiologie, Mosbach.
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  • [38]
    2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1631413
    Ragg, H. (2007). The role of serpins in the surveillance of the secretory pathway. CELL. MOL. LIFE SCI. 64, 2763-2770.
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  • [37]
    2006 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1953791
    Bentele, C., Krüger, O., Tödtmann, U., Oley, M., and Ragg, H. (2006). A proprotein convertase-inhibiting serpin with an ER targeting signal from Branchiostoma lanceolatum, a close relative of vertebrates. Biochem. J. 395, 449-456.
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  • [36]
    2006 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 1955145
    Bentele, C., Krüger, O., Tödtmann, U., Oley, M., and Ragg, H. (2006). “The role of serpins along the secretory pathway: regulation of prohormone convertases and beyond” in Gordon Research Conferences.
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  • [35]
    2005 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 1600740
    Oley, M., and Ragg, H. (2005). Target identification for Spn4, a gene encoding serpin isoforms with alternative reactive site loops. FEBS JOURNAL 272, 174-174.
    PUB | WoS
     
  • [34]
    2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1606208
    Brinkmeyer, S., Eckert, R., and Ragg, H. (2004). Reformable intramolecular cross-linking of the N-terminal domain of heparin cofactor II - Effects on enzyme inhibition. EUROPEAN JOURNAL OF BIOCHEMISTRY 271, 4275-4283.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [33]
    2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1953787
    Oley, M., Letzel, M., and Ragg, H. (2004). Inhibition of furin by serpin Spn4A from Drosophila melanogaster. FEBS Letters 577, 165-169.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [32]
    2003 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1953801
    Eckert, R., and Ragg, H. (2003). Zinc ions promote the interaction between heparin and heparin cofactor II. FEBS Letters 541, 121-125.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [31]
    2002 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1615250
    Böhme, C., Nimtz, M., Grabenhorst, E., Conradt, H. S., Strathmann, A., and Ragg, H. (2002). Tyrosine sulfation and N-glycosylation of human heparin cofactor II from plasma and recombinant Chinese hamster ovary cells and their effects on heparin binding. EUROPEAN JOURNAL OF BIOCHEMISTRY 269, 977-988.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [30]
    2002 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1613937
    Krüger, O., Ladewig, J., Köster, K., and Ragg, H. (2002). Widespread occurrence of serpin genes with multiple reactive centre-containing exon cassettes in insects and nematodes. GENE 293, 97-105.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [29]
    2001 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 1955179
    Brinkmeyer, S., Eckert, R., and Ragg, H. (2001).“Evidence for allosteric activation of heparin cofactor II in the presence of heparin or dermatan sulfate”. Presented at the XVIIIth Congress of the International Society on Thrombosis and Haemostasis, Paris.
    PUB
     
  • [28]
    2001 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1617557
    Ragg, H., Lokot, T., Kamp, P. - B., Atchley, W. R., and Dress, A. (2001). Vertebrate serpins: Construction of a conflict-free phylogeny by combining exon-intron and diagnostic site analyses. MOLECULAR BIOLOGY AND EVOLUTION 18, 577-584.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [27]
    2001 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1616585
    Atchley, W. R., Lokot, T., Wollenberg, K., Dress, A., and Ragg, H. (2001). Phylogenetic analyses of amino acid variation in the serpin proteins. MOLECULAR BIOLOGY AND EVOLUTION 18, 1502-1511.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [26]
    2001 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1617446
    Kamp, P. - B., Strathmann, A., and Ragg, H. (2001). Heparin cofactor II, antithrombin-beta and their complexes with thrombin in human tissues. THROMBOSIS RESEARCH 101, 483-491.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [25]
    1999 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1623326
    Kamp, P. - B., and Ragg, H. (1999). Rapid changes in the exon/intron structure of a mammalian thrombin inhibitor gene. GENE 229, 137-144.
    PUB | DOI | WoS | PubMed | Europe PMC
     
  • [24]
    1997 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1954263
    Peyman, A., Ragg, H., Ulshöfer, T., Will, D. W., and Uhlmann, E. (1997). Enhanced specificity of minimally modified anti-c-myc oligonucleotides. Nucleosides & Nucleotides 16, 1215-1219.
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  • [23]
    1994 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1953772
    Westrup, D., and Ragg, H. (1994). Secondary thrombin-binding site, glycosaminoglycan binding domain and reactive center region of leuserpin-2 are strongly conserved in mammalian species. Biochim. Biophys. Acta 1217, 93-96.
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  • [22]
    1990 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1953759
    Ragg, H., Ulshöfer, T., and Gerewitz, J. (1990). On the activation of human leuserpin-2, a thrombin inhibitor, by glycosaminoglycans. J. Biol. Chem. 265, 5211-5218.
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  • [21]
    1990 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1953767
    Glauder, J., Ragg, H., Rauch, J., and Engels, J. W. (1990). Human peptidylglycine alpha-amidating monooxygenase: cDNA cloning and functional expression of a truncated form in COS cells. Biochem. Biophys. Res. Commun. 169, 551-558.
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  • [20]
    1990 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1953763
    Ragg, H., Ulshöfer, T., and Gerewitz, J. (1990). Glycosaminoglycan-mediated leuserpin-2/thrombin interaction: structure-function relationships. J. Biol. Chem. 265, 22386-22301.
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  • [19]
    1988 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1948728
    Ragg, H., and Preibisch, G. (1988). Structure and expression of the gene coding for the human serpin hLS2. J. Biol. Chem. 263, 12129-12134.
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  • [18]
    1987 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1948715
    Bröker, M., Ragg, H., and Karges, H. E. (1987). Expression of human antithrombin III in Saccharomyces cerevisiae and Schizosaccharomyces pombe. Biochim. Biophys. Acta 908, 203-213.
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  • [17]
    1987 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1948719
    Zettlmeissl, G., Ragg, H., and Karges, H. E. (1987). Expression of biologically active human antithrombin III in Chinese hamster ovary cells. Bio-Technology 5, 720-725.
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  • [16]
    1986 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1948704
    Ragg, H. (1986). A new member of the plasma protease inhibitor gene family. Nucleic Acids Res. 14, 1073-1088.
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  • [15]
    1985 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1948699
    Ryals, J., Dierks, P., Ragg, H., and Weissmann, C. (1985). A 46-nucleotide promotor segment from an IFN-alpha gene renders an unrelated promotor inducible by virus. Cell 41, 497-507.
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  • [14]
    1983 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1948696
    Ragg, H., and Weissmann, C. (1983). Not more than 117 base pairs of 5'-flanking sequence are required for inducible expression of a human IFN-alpha gene. Nature 303, 439-442.
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  • [13]
    1983 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 1954275
    Ragg, H., Weidle, U., Mantei, N., and Weissmann, C. (1983).“The induced transcription of a human IFN-alpha gene requires not more than 117 base pairs of 5'-flanking sequence”. Presented at the Second International TNO Meeting on the Biology of the Interferon System, Rotterdam.
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  • [12]
    1983 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1948675
    Kreuzaler, F., Ragg, H., Fautz, E., Kuhn, D. N., and Hahlbrock, K. (1983). UV-induction of chalcone synthase mRNA in cell suspension cultures of Petroselinum hortense. Proc. Natl. Acad. Sci. USA 80, 2591-2593.
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  • [11]
    1982 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1948687
    Hemleben, V., Frey, M., Rall, S., Koch, M., Kittel, M., Kreuzaler, F., Ragg, H., Fautz, E., and Hahlbrock, K. (1982). Studies on the chalcone synthase gene of two higher plants: Petroselinum hortense and Matthiola incana. Progr. Clin. Biol. Res. 85 (Pt B), 555-566.
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  • [10]
    1982 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1946278
    Wienand, U., Sommer, H., Schwarz, Z., Shepard, N., Saedler, H., Kreuzaler, F., Ragg, H., Fautz, E., and Hahlbrock, K. (1982). A general method to identify plant structural genes among genomic DNA clones using transposable element induced mutations. Mol. Gen. Genet. 187, 195-201.
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  • [9]
    1982 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1948634
    Weissmann, C., Nagata, S., Boll, W., Fountoulakis, M., Fujisawa, A., Fujisawa, J. - I., Haynes, J., Henco, K., Mantei, N., Ragg, H., et al. (1982). Structure and expression of human IFN-alpha genes. Philos. Trans. R. Soc. Lond. B 299, 7-28.
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  • [8]
    1982 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 1954292
    Hahlbrock, K., Kreuzaler, F., Ragg, H., Fautz, E., and Kuhn, D. N. (1982). “Regulation of flavonoid and phytoalexin accumulation through mRNA and enzyme induction in cultured plant cells” in 33. Colloquium der Gesellschaft für Biologische Chemie, Jaenicke, L. ed. (Berlin: Springer-Verlag), 34-43.
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  • [7]
    1981 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1945081
    Ragg, H., Kuhn, D. N., and Hahlbrock, K. (1981). Coordinated regulation of 4-coumarate: CoA ligase and phenylalanine ammonia-lyase mRNAs in cultured plant cells. J. Biol. Chem. 256, 10061-10065.
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  • [6]
    1980 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1945070
    Ragg, H., and Hahlbrock, K. (1980). Messenger RNA coding for phenylalanine ammonia-lyase: Characterization and partial purification from cell suspension cultures of Petroselinum hortense. Eur. J. Biochem. 103, 323-330.
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  • [5]
    1979 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1945064
    Kreuzaler, F., Ragg, H., Heller, W., Tesch, R., Witt, I., Hammer, D., and Hahlbrock, K. (1979). Flavanone synthase from Petroselinum hortense: Molecular weight, subunit composition, size of messenger RNA, and absence of panthetheinyl residue. Eur. J. Biochem. 99, 89-96.
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  • [4]
    1978 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 1954304
    Hahlbrock, K., Betz, B., Gardiner, S. E., Kreuzaler, F., Matern, U., Ragg, H., Schäfer, E., and Schröder, J. (1978).“Enzyme induction in cultured cells”. Presented at the Proceedings of the 4th International Congress of Plant Tissue and Cell Culture, Calgary, Alberta, Canada.
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  • [3]
    1977 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1945055
    Ragg, H., Schröder, J., and Hahlbrock, K. (1977). Translation of poly(A)-containing and poly(A)-free messenger RNA for phenylalanine ammonia-lyase, a plant-specific protein, in a reticulocyte lysate. Biochim. Biophys. Acta 474, 226-233.
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  • [2]
    1975 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1941362
    Hahlbrock, K., and Ragg, H. (1975). Light-induced changes of enzyme activities in parsley suspension cultures: Effects of inhibitors of RNA and protein synthesis. Arch. Biochem. Biophys. 166, 41-46.
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  • [1]
    1975 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1941368
    Ragg, H., Schröder, J., and Hahlbrock, K. (1975). Poly(A)-containing RNA from Petroselinum hortense: Isolation, properties and messenger function in vitro. Molecular Biology Reports 2, 119-127.
    PUB
     

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