52 Publikationen
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2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2907725Wei, H., Cai, H., Wu, J., Wei, Z., Zhang, F., Huang, X., Ma, L., et al. (2016). Heparin Binds Lamprey Angiotensinogen and Promotes Thrombin Inhibition through a Template Mechanism. JOURNAL OF BIOLOGICAL CHEMISTRY, 291(48), 24900-24911. doi:10.1074/jbc.M116.725895
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2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2690864Sfaxi, F., Scamuffa, N., Lalou, C., Ma, J., Metrakos, P., Siegfried, G., Ragg, H., et al. (2014). Repression of liver colorectal metastasis by the serpin Spn4A a naturally occurring inhibitor of the constitutive secretory proprotein convertases. Oncotarget, 5(12), 4195-4210. doi:10.18632/oncotarget.1966
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2011 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 2423346Wang, Y., & Ragg, H. (2011). Angiotensinogen: the multi-faceted nature of an ancient vertebrate serpin. Presented at the 6th International Symposium on the Chemistry and Biology of Serpins, Raleigh, North Carolina
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2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2423353Börner, S., & Ragg, H. (2011). Bioinformatic approaches for the identification of serpin genes with multiple reactive site loop coding exons. Methods in Enzymology, 501, 209-222. https://doi.org/10.1016/B978-0-12-385950-1.00010-9
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2011 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 2423350Ragg, H., & Wang, Y. (2011). How control of thrombin by serpins in vertebrates arose. Abstracts of the XXIII Congress of the International Society on Thrombosis and Haemostasis 57th Annual SSC Meeting, July 23-28 2011, Kyoto, Japan, Journal of Thrombosis and Haemostasis, 9, 723. Wiley.
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2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1948655Ragg, H. (2011). Intron creation and DNA repair. Cell. Mol. Life Sci., 68(2), 235-242. https://doi.org/10.1007/s00018-010-0532-2
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2011 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2307100Wang, Y., & Ragg, H. (2011). An unexpected link between angiotensinogen and thrombin. FEBS Letters, 585(14), 2395-2399. https://doi.org/10.1016/j.febslet.2011.06.021
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2009 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1784544Ragg, H., Kumar, A., Köster, K., Bentele, C., Wang, Y., Frese, M. - A., Prib, N., et al. (2009). Multiple gains of spliceosomal introns in a superfamily of vertebrate protease inhibitor genes. BMC Evolutionary Biology, 9(1), 208. https://doi.org/10.1186/1471-2148-9-208
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2008 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 1955161Börner, S., & Ragg, H. (2008). Multitasking serpin genes in the genus Drosophila and beyond: evolution and functional diversification. Presented at the Serpins 2008, 5th International Symposium on Serpin Biology, Structure and Function, Leuwen, Belgium
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2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1783341Kumar, A., & Ragg, H. (2008). Ancestry and evolution of a secretory pathway serpin. BMC Evolutionary Biology, 8(1), 250. https://doi.org/10.1186/1471-2148-8-250
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2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1587736Börner, S., & Ragg, H. (2008). Functional diversification of a protease inhibitor gene in the genus Drosophila and its molecular basis. GENE, 415(1-2), 23-31. https://doi.org/10.1016/j.gene.2008.02.004
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2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1953796Brüning, M., Lummer, M., Bentele, C., Smolenaars, M. M. W., Rodenburg, K. W., & Ragg, H. (2007). The Spn4 gene from Drosophila melanogaster is a multipurpose defense tool directed against proteases from three different peptidase families. Biochem. J., 401(1), 325-331. https://doi.org/10.1042/BJ20060648
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2007 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 1955191Bentele, C., Oley, M., Tödtmann, U., Krüger, O., & Ragg, H. (2007). Proprotein convertase inhibiting serpins along the secretory pathway. Presented at the Mosbacher Kolloquium der Gesellschaft für Biochemie und Molekularbiologie, Mosbach
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2007 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1631413Ragg, H. (2007). The role of serpins in the surveillance of the secretory pathway. CELL. MOL. LIFE SCI., 64(21), 2763-2770. https://doi.org/10.1007/s00018-007-7157-0
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2006 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1953791Bentele, C., Krüger, O., Tödtmann, U., Oley, M., & Ragg, H. (2006). A proprotein convertase-inhibiting serpin with an ER targeting signal from Branchiostoma lanceolatum, a close relative of vertebrates. Biochem. J., 395(3), 449-456. https://doi.org/10.1042/BJ20051947
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2006 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 1955145Bentele, C., Krüger, O., Tödtmann, U., Oley, M., & Ragg, H. (2006). The role of serpins along the secretory pathway: regulation of prohormone convertases and beyond. Gordon Research Conferences
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2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1606208Brinkmeyer, S., Eckert, R., & Ragg, H. (2004). Reformable intramolecular cross-linking of the N-terminal domain of heparin cofactor II - Effects on enzyme inhibition. EUROPEAN JOURNAL OF BIOCHEMISTRY, 271(21), 4275-4283. https://doi.org/10.1111/j.1432-1033.2004.04367.x
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2004 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1953787Oley, M., Letzel, M., & Ragg, H. (2004). Inhibition of furin by serpin Spn4A from Drosophila melanogaster. FEBS Letters, 577(1-2), 165-169. https://doi.org/10.1016/j.febslet.2004.10.003
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2003 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1953801Eckert, R., & Ragg, H. (2003). Zinc ions promote the interaction between heparin and heparin cofactor II. FEBS Letters, 541(1-3), 121-125. https://doi.org/10.1016/S0014-5793(03)00322-3
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2002 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1615250Böhme, C., Nimtz, M., Grabenhorst, E., Conradt, H. S., Strathmann, A., & Ragg, H. (2002). Tyrosine sulfation and N-glycosylation of human heparin cofactor II from plasma and recombinant Chinese hamster ovary cells and their effects on heparin binding. EUROPEAN JOURNAL OF BIOCHEMISTRY, 269(3), 977-988. https://doi.org/10.1046/j.0014-2956.2001.02732.x
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2002 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1613937Krüger, O., Ladewig, J., Köster, K., & Ragg, H. (2002). Widespread occurrence of serpin genes with multiple reactive centre-containing exon cassettes in insects and nematodes. GENE, 293(1-2), 97-105. https://doi.org/10.1016/S0378-1119(02)00697-2
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2001 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 1955179Brinkmeyer, S., Eckert, R., & Ragg, H. (2001). Evidence for allosteric activation of heparin cofactor II in the presence of heparin or dermatan sulfate. Presented at the XVIIIth Congress of the International Society on Thrombosis and Haemostasis, Paris.
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2001 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1617557Ragg, H., Lokot, T., Kamp, P. - B., Atchley, W. R., & Dress, A. (2001). Vertebrate serpins: Construction of a conflict-free phylogeny by combining exon-intron and diagnostic site analyses. MOLECULAR BIOLOGY AND EVOLUTION, 18(4), 577-584. https://doi.org/10.1093/oxfordjournals.molbev.a003838
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2001 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1616585Atchley, W. R., Lokot, T., Wollenberg, K., Dress, A., & Ragg, H. (2001). Phylogenetic analyses of amino acid variation in the serpin proteins. MOLECULAR BIOLOGY AND EVOLUTION, 18(8), 1502-1511. https://doi.org/10.1093/oxfordjournals.molbev.a003936
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2001 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1617446Kamp, P. - B., Strathmann, A., & Ragg, H. (2001). Heparin cofactor II, antithrombin-beta and their complexes with thrombin in human tissues. THROMBOSIS RESEARCH, 101(6), 483-491. https://doi.org/10.1016/S0049-3848(00)00422-9
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1999 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1623326Kamp, P. - B., & Ragg, H. (1999). Rapid changes in the exon/intron structure of a mammalian thrombin inhibitor gene. GENE, 229(1-2), 137-144. https://doi.org/10.1016/S0378-1119(99)00036-0
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1997 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1954263Peyman, A., Ragg, H., Ulshöfer, T., Will, D. W., & Uhlmann, E. (1997). Enhanced specificity of minimally modified anti-c-myc oligonucleotides. Nucleosides & Nucleotides, 16, 1215-1219.
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1994 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1953772Westrup, D., & Ragg, H. (1994). Secondary thrombin-binding site, glycosaminoglycan binding domain and reactive center region of leuserpin-2 are strongly conserved in mammalian species. Biochim. Biophys. Acta, 1217, 93-96.
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1990 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1953759Ragg, H., Ulshöfer, T., & Gerewitz, J. (1990). On the activation of human leuserpin-2, a thrombin inhibitor, by glycosaminoglycans. J. Biol. Chem., 265, 5211-5218.
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1990 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1953767Glauder, J., Ragg, H., Rauch, J., & Engels, J. W. (1990). Human peptidylglycine alpha-amidating monooxygenase: cDNA cloning and functional expression of a truncated form in COS cells. Biochem. Biophys. Res. Commun., 169, 551-558.
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1990 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1953763Ragg, H., Ulshöfer, T., & Gerewitz, J. (1990). Glycosaminoglycan-mediated leuserpin-2/thrombin interaction: structure-function relationships. J. Biol. Chem., 265, 22386-22301.
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1988 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1948728Ragg, H., & Preibisch, G. (1988). Structure and expression of the gene coding for the human serpin hLS2. J. Biol. Chem., 263, 12129-12134.
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1987 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1948715Bröker, M., Ragg, H., & Karges, H. E. (1987). Expression of human antithrombin III in Saccharomyces cerevisiae and Schizosaccharomyces pombe. Biochim. Biophys. Acta, 908, 203-213.
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1987 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1948719Zettlmeissl, G., Ragg, H., & Karges, H. E. (1987). Expression of biologically active human antithrombin III in Chinese hamster ovary cells. Bio-Technology, 5, 720-725.
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1986 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1948704Ragg, H. (1986). A new member of the plasma protease inhibitor gene family. Nucleic Acids Res., 14, 1073-1088.
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1985 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1948699Ryals, J., Dierks, P., Ragg, H., & Weissmann, C. (1985). A 46-nucleotide promotor segment from an IFN-alpha gene renders an unrelated promotor inducible by virus. Cell, 41, 497-507.
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1983 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1948696Ragg, H., & Weissmann, C. (1983). Not more than 117 base pairs of 5'-flanking sequence are required for inducible expression of a human IFN-alpha gene. Nature, 303, 439-442.
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1983 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 1954275Ragg, H., Weidle, U., Mantei, N., & Weissmann, C. (1983). The induced transcription of a human IFN-alpha gene requires not more than 117 base pairs of 5'-flanking sequence. Presented at the Second International TNO Meeting on the Biology of the Interferon System, Rotterdam
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1983 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1948675Kreuzaler, F., Ragg, H., Fautz, E., Kuhn, D. N., & Hahlbrock, K. (1983). UV-induction of chalcone synthase mRNA in cell suspension cultures of Petroselinum hortense. Proc. Natl. Acad. Sci. USA, 80, 2591-2593.
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1982 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1948687Hemleben, V., Frey, M., Rall, S., Koch, M., Kittel, M., Kreuzaler, F., Ragg, H., et al. (1982). Studies on the chalcone synthase gene of two higher plants: Petroselinum hortense and Matthiola incana. Progr. Clin. Biol. Res., 85 (Pt B), 555-566.
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1982 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1946278Wienand, U., Sommer, H., Schwarz, Z., Shepard, N., Saedler, H., Kreuzaler, F., Ragg, H., et al. (1982). A general method to identify plant structural genes among genomic DNA clones using transposable element induced mutations. Mol. Gen. Genet., 187, 195-201.
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1982 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1948634Weissmann, C., Nagata, S., Boll, W., Fountoulakis, M., Fujisawa, A., Fujisawa, J. - I., Haynes, J., et al. (1982). Structure and expression of human IFN-alpha genes. Philos. Trans. R. Soc. Lond. B, 299(1094), 7-28.
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1982 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 1954292Hahlbrock, K., Kreuzaler, F., Ragg, H., Fautz, E., & Kuhn, D. N. (1982). Regulation of flavonoid and phytoalexin accumulation through mRNA and enzyme induction in cultured plant cells. In L. Jaenicke (Ed.), 33. Colloquium der Gesellschaft für Biologische Chemie (pp. 34-43). Berlin: Springer-Verlag.
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1981 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1945081Ragg, H., Kuhn, D. N., & Hahlbrock, K. (1981). Coordinated regulation of 4-coumarate: CoA ligase and phenylalanine ammonia-lyase mRNAs in cultured plant cells. J. Biol. Chem., 256, 10061-10065.
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1980 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1945070Ragg, H., & Hahlbrock, K. (1980). Messenger RNA coding for phenylalanine ammonia-lyase: Characterization and partial purification from cell suspension cultures of Petroselinum hortense. Eur. J. Biochem., 103, 323-330.
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1979 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1945064Kreuzaler, F., Ragg, H., Heller, W., Tesch, R., Witt, I., Hammer, D., & Hahlbrock, K. (1979). Flavanone synthase from Petroselinum hortense: Molecular weight, subunit composition, size of messenger RNA, and absence of panthetheinyl residue. Eur. J. Biochem., 99, 89-96.
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1978 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 1954304Hahlbrock, K., Betz, B., Gardiner, S. E., Kreuzaler, F., Matern, U., Ragg, H., Schäfer, E., et al. (1978). Enzyme induction in cultured cells. Presented at the Proceedings of the 4th International Congress of Plant Tissue and Cell Culture, Calgary, Alberta, Canada.
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1977 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1945055Ragg, H., Schröder, J., & Hahlbrock, K. (1977). Translation of poly(A)-containing and poly(A)-free messenger RNA for phenylalanine ammonia-lyase, a plant-specific protein, in a reticulocyte lysate. Biochim. Biophys. Acta, 474, 226-233.
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1975 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1941362Hahlbrock, K., & Ragg, H. (1975). Light-induced changes of enzyme activities in parsley suspension cultures: Effects of inhibitors of RNA and protein synthesis. Arch. Biochem. Biophys., 166, 41-46.
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1975 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1941368Ragg, H., Schröder, J., & Hahlbrock, K. (1975). Poly(A)-containing RNA from Petroselinum hortense: Isolation, properties and messenger function in vitro. Molecular Biology Reports, 2, 119-127.