The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its impact on the production of L-aspartate-derived amino acids and vitamins

Kalinowski J, Bathe B, Bartels D, Bischoff N, Bott M, Burkovski A, Dusch N, Eggeling L, Eikmanns BJ, Gaigalat L, Goesmann A, et al. (2003)
Journal of Biotechnology 104(1-3): 5-25.

Zeitschriftenaufsatz | Veröffentlicht | Englisch
 
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DOI
Autor*in
Kalinowski, JörnUniBi; Bathe, B.; Bartels, D.; Bischoff, N.; Bott, M.; Burkovski, A.; Dusch, N.; Eggeling, L.; Eikmanns, B. J.; Gaigalat, L.; Goesmann, AlexanderUniBi ; Hartmann, M.
Alle
Einrichtung
Centrum für Biotechnologie > Arbeitsgruppe A. Goesmann
Centrum für Biotechnologie > Arbeitsgruppe A. Tauch
Fakultät für Biologie > Genetik der Prokaryoten
Centrum für Biotechnologie > Institut für Genomforschung und Systembiologie
Centrum für Biotechnologie > Arbeitsgruppe J. Kalinowski
Centrum für Biotechnologie > Arbeitsgruppe V. Wendisch
Centrum für Biotechnologie > Arbeitsgruppe A. Pühler
Centrum für Biotechnologie > Technologieplattformen > Bioinformatics Resource Facility
Abstract / Bemerkung
The complete genomic sequence of Corynebacterium glutainicum ATCC 13032, well-known in industry for the production of amino acids, e.g. of L-glutamate and L-lysine was determined. The C glutamician genome was found to consist of a single circular chromosome comprising 3 282 708 base pairs. Several DNA regions of unusual composition were identified that were potentially acquired by horizontal gene transfer, e.g. a segment of DNA from C diphtheriae and a prophage-containing region. After automated and manual annotation, 3002 protein-coding genes have been identified, and to 2489 of these, functions were assigned by homologies to known proteins. These analyses confirm the taxonomic position of C glutamicum as related to Mycobacteria and show a broad metabolic diversity as expected for a bacterium living in the soil. As an example for biotechnological application the complete genome sequence was used to reconstruct the metabolic flow of carbon into a number of industrially important products derived from the amino acid L-aspartate. (C) 2003 Elsevier B.V. All rights reserved.
Stichworte
coryneform bacteria; biochemical-characterization; molecular analysis; nucleotide-sequence; vitamin production; bioinformatics; fine-structural analysis; genome sequence; amino acid production; corynebacterium glutamicum; pantothenate overproduction; phosphotransferase system; brevibacterium-flavum; l-isoleucine; escherichia-coli
Erscheinungsjahr
2003
Zeitschriftentitel
Journal of Biotechnology
Band
104
Ausgabe
1-3
Seite(n)
5-25
ISSN
0168-1656
Page URI
https://pub.uni-bielefeld.de/record/1895035

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Kalinowski J, Bathe B, Bartels D, et al. The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its impact on the production of L-aspartate-derived amino acids and vitamins. Journal of Biotechnology. 2003;104(1-3):5-25.
Kalinowski, J., Bathe, B., Bartels, D., Bischoff, N., Bott, M., Burkovski, A., Dusch, N., et al. (2003). The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its impact on the production of L-aspartate-derived amino acids and vitamins. Journal of Biotechnology, 104(1-3), 5-25. https://doi.org/10.1016/S0168-1656(03)00154-8
Kalinowski, Jörn, Bathe, B., Bartels, D., Bischoff, N., Bott, M., Burkovski, A., Dusch, N., et al. 2003. “The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its impact on the production of L-aspartate-derived amino acids and vitamins”. Journal of Biotechnology 104 (1-3): 5-25.
Kalinowski, J., Bathe, B., Bartels, D., Bischoff, N., Bott, M., Burkovski, A., Dusch, N., Eggeling, L., Eikmanns, B. J., Gaigalat, L., et al. (2003). The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its impact on the production of L-aspartate-derived amino acids and vitamins. Journal of Biotechnology 104, 5-25.
Kalinowski, J., et al., 2003. The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its impact on the production of L-aspartate-derived amino acids and vitamins. Journal of Biotechnology, 104(1-3), p 5-25.
J. Kalinowski, et al., “The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its impact on the production of L-aspartate-derived amino acids and vitamins”, Journal of Biotechnology, vol. 104, 2003, pp. 5-25.
Kalinowski, J., Bathe, B., Bartels, D., Bischoff, N., Bott, M., Burkovski, A., Dusch, N., Eggeling, L., Eikmanns, B.J., Gaigalat, L., Goesmann, A., Hartmann, M., Huthmacher, K., Kramer, R., Linke, B., McHardy, A.C., Meyer, F., Mockel, B., Pfefferle, W., Pühler, A., Rey, D.A., Rückert, C., Rupp, O., Sahm, H., Wendisch, V.F., Wiegrabe, I., Tauch, A.: The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its impact on the production of L-aspartate-derived amino acids and vitamins. Journal of Biotechnology. 104, 5-25 (2003).
Kalinowski, Jörn, Bathe, B., Bartels, D., Bischoff, N., Bott, M., Burkovski, A., Dusch, N., Eggeling, L., Eikmanns, B. J., Gaigalat, L., Goesmann, Alexander, Hartmann, M., Huthmacher, K., Kramer, R., Linke, Burkhard, McHardy, A. C., Meyer, F., Mockel, B., Pfefferle, W., Pühler, Alfred, Rey, D. A., Rückert, Christian, Rupp, O., Sahm, H., Wendisch, Volker F., Wiegrabe, I., and Tauch, Andreas. “The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its impact on the production of L-aspartate-derived amino acids and vitamins”. Journal of Biotechnology 104.1-3 (2003): 5-25.

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Komati Reddy G, Lindner SN, Wendisch VF., Appl Environ Microbiol 81(6), 2015
PMID: 25576602
Comparative studies for the biotechnological production of L-Lysine by immobilized cells of wild-type Corynebacterium glutamicum ATCC 13032 and mutant MH 20-22 B.
Razak MA, Viswanath B., 3 Biotech 5(5), 2015
PMID: 28324528
Comparative proteome analysis of global effect of POS5 and zwf-ppnK overexpression in L-isoleucine producing Corynebacterium glutamicum ssp. lactofermentum.
Shi F, Li K, Li Y., Biotechnol Lett 37(5), 2015
PMID: 25650341
The α-glucan phosphorylase MalP of Corynebacterium glutamicum is subject to transcriptional regulation and competitive inhibition by ADP-glucose.
Clermont L, Macha A, Müller LM, Derya SM, von Zaluskowski P, Eck A, Eikmanns BJ, Seibold GM., J Bacteriol 197(8), 2015
PMID: 25666133
Advanced biotechnology: metabolically engineered cells for the bio-based production of chemicals and fuels, materials, and health-care products.
Becker J, Wittmann C., Angew Chem Int Ed Engl 54(11), 2015
PMID: 25684732
Overexpression of ribosome elongation factor G and recycling factor increases L-isoleucine production in Corynebacterium glutamicum.
Zhao J, Hu X, Li Y, Wang X., Appl Microbiol Biotechnol 99(11), 2015
PMID: 25707863
4-Hydroxyisoleucine production of recombinant Corynebacterium glutamicum ssp. lactofermentum under optimal corn steep liquor limitation.
Shi F, Niu T, Fang H., Appl Microbiol Biotechnol 99(9), 2015
PMID: 25725632
Metabolic engineering of Corynebacterium glutamicum ATCC13869 for L-valine production.
Chen C, Li Y, Hu J, Dong X, Wang X., Metab Eng 29(), 2015
PMID: 25769288
Metabolic engineering in the biotechnological production of organic acids in the tricarboxylic acid cycle of microorganisms: Advances and prospects.
Yin X, Li J, Shin HD, Du G, Liu L, Chen J., Biotechnol Adv 33(6 pt 1), 2015
PMID: 25902192
A prophage-encoded actin-like protein required for efficient viral DNA replication in bacteria.
Donovan C, Heyer A, Pfeifer E, Polen T, Wittmann A, Krämer R, Frunzke J, Bramkamp M., Nucleic Acids Res 43(10), 2015
PMID: 25916847
Complete genome sequence of Corynebacterium glutamicum B253, a Chinese lysine-producing strain.
Wu Y, Li P, Zheng P, Zhou W, Chen N, Sun J., J Biotechnol 207(), 2015
PMID: 25953304
Synthesis of chemicals by metabolic engineering of microbes.
Sun X, Shen X, Jain R, Lin Y, Wang J, Sun J, Wang J, Yan Y, Yuan Q., Chem Soc Rev 44(11), 2015
PMID: 25940754
Co-production of S-adenosyl-L-methionine and L-isoleucine in Corynebacterium glutamicum.
Han G, Hu X, Wang X., Enzyme Microb Technol 78(), 2015
PMID: 26215341
Metabolic pathway engineering for production of 1,2-propanediol and 1-propanol by Corynebacterium glutamicum.
Siebert D, Wendisch VF., Biotechnol Biofuels 8(), 2015
PMID: 26110019
Identification of axillary Staphylococcus sp. involved in the production of the malodorous thioalcohol 3-methyl-3-sufanylhexan-1-ol.
Bawdon D, Cox DS, Ashford D, James AG, Thomas GH., FEMS Microbiol Lett 362(16), 2015
PMID: 26163522
Exploring the role of sigma factor gene expression on production by Corynebacterium glutamicum: sigma factor H and FMN as example.
Taniguchi H, Wendisch VF., Front Microbiol 6(), 2015
PMID: 26257719
Engineering microbial cell factories: Metabolic engineering of Corynebacterium glutamicum with a focus on non-natural products.
Heider SA, Wendisch VF., Biotechnol J 10(8), 2015
PMID: 26216246
Anaerobic growth of Corynebacterium glutamicum via mixed-acid fermentation.
Michel A, Koch-Koerfges A, Krumbach K, Brocker M, Bott M., Appl Environ Microbiol 81(21), 2015
PMID: 26276118
Single-Domain Peptidyl-Prolyl cis/trans Isomerase FkpA from Corynebacterium glutamicum Improves the Biomass Yield at Increased Growth Temperatures.
Kallscheuer N, Bott M, van Ooyen J, Polen T., Appl Environ Microbiol 81(22), 2015
PMID: 26341203
Advances and needs for endotoxin-free production strains.
Taguchi S, Ooi T, Mizuno K, Matsusaki H., Appl Microbiol Biotechnol 99(22), 2015
PMID: 26362682
Biosensor-driven adaptive laboratory evolution of l-valine production in Corynebacterium glutamicum.
Mahr R, Gätgens C, Gätgens J, Polen T, Kalinowski J, Frunzke J., Metab Eng 32(), 2015
PMID: 26453945
Identification of two mutations increasing the methanol tolerance of Corynebacterium glutamicum.
Leßmeier L, Wendisch VF., BMC Microbiol 15(), 2015
PMID: 26474849
Engineering Corynebacterium glutamicum to produce 5-aminolevulinic acid from glucose.
Yu X, Jin H, Liu W, Wang Q, Qi Q., Microb Cell Fact 14(), 2015
PMID: 26577071
The Ligands of Neutrophil Gelatinase-Associated Lipocalin.
Bao GH, Ho CT, Barasch J., RSC Adv 5(126), 2015
PMID: 27617081
Enhanced production of recombinant proteins with Corynebacterium glutamicum by deletion of insertion sequences (IS elements).
Choi JW, Yim SS, Kim MJ, Jeong KJ., Microb Cell Fact 14(), 2015
PMID: 26715464
Histidine biosynthesis, its regulation and biotechnological application in Corynebacterium glutamicum.
Kulis-Horn RK, Persicke M, Kalinowski J., Microb Biotechnol 7(1), 2014
PMID: 23617600
Beyond growth rate 0.6: What drives Corynebacterium glutamicum to higher growth rates in defined medium.
Unthan S, Grünberger A, van Ooyen J, Gätgens J, Heinrich J, Paczia N, Wiechert W, Kohlheyer D, Noack S., Biotechnol Bioeng 111(2), 2014
PMID: 23996851
Aerobic production of succinate from arabinose by metabolically engineered Corynebacterium glutamicum.
Chen T, Zhu N, Xia H., Bioresour Technol 151(), 2014
PMID: 24169202
Improved succinate production in Corynebacterium glutamicum by engineering glyoxylate pathway and succinate export system.
Zhu N, Xia H, Yang J, Zhao X, Chen T., Biotechnol Lett 36(3), 2014
PMID: 24129953
The Tat system of Gram-positive bacteria.
Goosens VJ, Monteferrante CG, van Dijl JM., Biochim Biophys Acta 1843(8), 2014
PMID: 24140208
Pushing product formation to its limit: metabolic engineering of Corynebacterium glutamicum for L-leucine overproduction.
Vogt M, Haas S, Klaffl S, Polen T, Eggeling L, van Ooyen J, Bott M., Metab Eng 22(), 2014
PMID: 24333966
The pyruvate dehydrogenase complex of Corynebacterium glutamicum: an attractive target for metabolic engineering.
Eikmanns BJ, Blombach B., J Biotechnol 192 Pt B(), 2014
PMID: 24486441
Engineering biotin prototrophic Corynebacterium glutamicum strains for amino acid, diamine and carotenoid production.
Peters-Wendisch P, Götker S, Heider SA, Komati Reddy G, Nguyen AQ, Stansen KC, Wendisch VF., J Biotechnol 192 Pt B(), 2014
PMID: 24486440
Metabolic engineering of Corynebacterium glutamicum for glycolate production.
Zahoor A, Otten A, Wendisch VF., J Biotechnol 192 Pt B(), 2014
PMID: 24486442
Effect of biotin on transcription levels of key enzymes and glutamate efflux in glutamate fermentation by Corynebacterium glutamicum
Cao Y, Duan Z, Shi Z., World J Microbiol Biotechnol 30(2), 2014
PMID: IND500721673
High-throughput screening of a Corynebacterium glutamicum mutant library on genomic and metabolic level.
Reimer LC, Spura J, Schmidt-Hohagen K, Schomburg D., PLoS One 9(2), 2014
PMID: 24504095
The physiological role of riboflavin transporter and involvement of FMN-riboswitch in its gene expression in Corynebacterium glutamicum.
Takemoto N, Tanaka Y, Inui M, Yukawa H., Appl Microbiol Biotechnol 98(9), 2014
PMID: 24531272
Analysis of cepA encoding an efflux pump-like protein in Corynebacterium glutamicum.
Sim SY, Hong EJ, Kim Y, Lee HS., J Microbiol 52(4), 2014
PMID: 24535744
Engineering of Corynebacterium glutamicum for growth and L-lysine and lycopene production from N-acetyl-glucosamine.
Matano C, Uhde A, Youn JW, Maeda T, Clermont L, Marin K, Krämer R, Wendisch VF, Seibold GM., Appl Microbiol Biotechnol 98(12), 2014
PMID: 24668244
Role of Corynebacterium glutamicum sprA encoding a serine protease in glxR-mediated global gene regulation.
Hong EJ, Park JS, Kim Y, Lee HS., PLoS One 9(4), 2014
PMID: 24691519
Synthetic biology platform of CoryneBrick vectors for gene expression in Corynebacterium glutamicum and its application to xylose utilization.
Kang MK, Lee J, Um Y, Lee TS, Bott M, Park SJ, Woo HM., Appl Microbiol Biotechnol 98(13), 2014
PMID: 24706215
Cell division in Corynebacterineae.
Donovan C, Bramkamp M., Front Microbiol 5(), 2014
PMID: 24782835
Double mutation of cell wall proteins CspB and PBP1a increases secretion of the antibody Fab fragment from Corynebacterium glutamicum.
Matsuda Y, Itaya H, Kitahara Y, Theresia NM, Kutukova EA, Yomantas YA, Date M, Kikuchi Y, Wachi M., Microb Cell Fact 13(1), 2014
PMID: 24731213
Involvement of the global regulator GlxR in 3-hydroxybenzoate and gentisate utilization by Corynebacterium glutamicum.
Chao H, Zhou NY., Appl Environ Microbiol 80(14), 2014
PMID: 24795375
Pupylated proteins in Corynebacterium glutamicum revealed by MudPIT analysis.
Küberl A, Fränzel B, Eggeling L, Polen T, Wolters DA, Bott M., Proteomics 14(12), 2014
PMID: 24737727
Biosynthesis of trans-4-hydroxyproline by recombinant strains of Corynebacterium glutamicum and Escherichia coli.
Yi Y, Sheng H, Li Z, Ye Q., BMC Biotechnol 14(), 2014
PMID: 24885047
High-resolution melt analysis for rapid comparison of bacterial community compositions.
Hjelmsø MH, Hansen LH, Baelum J, Feld L, Holben WE, Jacobsen CS., Appl Environ Microbiol 80(12), 2014
PMID: 24610853
Transcriptome sequencing revealed the transcriptional organization at ribosome-mediated attenuation sites in Corynebacterium glutamicum and identified a novel attenuator involved in aromatic amino acid biosynthesis.
Neshat A, Mentz A, Rückert C, Kalinowski J., J Biotechnol 190(), 2014
PMID: 24910972
Biosynthesis of pinene from glucose using metabolically-engineered Corynebacterium glutamicum.
Kang MK, Eom JH, Kim Y, Um Y, Woo HM., Biotechnol Lett 36(10), 2014
PMID: 24930112
Genome-wide analysis of the role of global transcriptional regulator GntR1 in Corynebacterium glutamicum.
Tanaka Y, Takemoto N, Ito T, Teramoto H, Yukawa H, Inui M., J Bacteriol 196(18), 2014
PMID: 24982307
Succinate production from CO₂-grown microalgal biomass as carbon source using engineered Corynebacterium glutamicum through consolidated bioprocessing.
Lee J, Sim SJ, Bott M, Um Y, Oh MK, Woo HM., Sci Rep 4(), 2014
PMID: 25056811
Transcriptional response of Corynebacterium glutamicum ATCC 13032 to hydrogen peroxide stress and characterization of the OxyR regulon.
Milse J, Petri K, Rückert C, Kalinowski J., J Biotechnol 190(), 2014
PMID: 25107507
Construction of a novel expression system for use in Corynebacterium glutamicum.
Hu J, Li Y, Zhang H, Tan Y, Wang X., Plasmid 75(), 2014
PMID: 25108235
Characterization of a Corynebacterium glutamicum dnaB mutant that shows temperature-sensitive growth and mini-cell formation.
Uchida M, Hirasawa T, Wachi M., Arch Microbiol 196(12), 2014
PMID: 25141796
Crystal structure of Clostridium acetobutylicum Aspartate kinase (CaAK): An important allosteric enzyme for amino acids production.
Manjasetty BA, Chance MR, Burley SK, Panjikar S, Almo SC., Biotechnol Rep (Amst) 3(), 2014
PMID: 25170437
Improved production of poly(lactic acid)-like polyester based on metabolite analysis to address the rate-limiting step.
Matsumoto K, Tobitani K, Aoki S, Song Y, Ooi T, Taguchi S., AMB Express 4(1), 2014
PMID: 26267112
Metabolic engineering of microorganisms for the production of L-arginine and its derivatives.
Shin JH, Lee SY., Microb Cell Fact 13(), 2014
PMID: 25467280
Glycerol as a substrate for aerobic succinate production in minimal medium with Corynebacterium glutamicum.
Litsanov B, Brocker M, Bott M., Microb Biotechnol 6(2), 2013
PMID: 22513227
Glucosamine as carbon source for amino acid-producing Corynebacterium glutamicum.
Uhde A, Youn JW, Maeda T, Clermont L, Matano C, Krämer R, Wendisch VF, Seibold GM, Marin K., Appl Microbiol Biotechnol 97(4), 2013
PMID: 22854894
Destabilized eYFP variants for dynamic gene expression studies in Corynebacterium glutamicum.
Hentschel E, Will C, Mustafi N, Burkovski A, Rehm N, Frunzke J., Microb Biotechnol 6(2), 2013
PMID: 22938655
A propionate-inducible expression system based on the Corynebacterium glutamicum prpD2 promoter and PrpR activator and its application for the redirection of amino acid biosynthesis pathways.
Plassmeier JK, Busche T, Molck S, Persicke M, Pühler A, Rückert C, Kalinowski J., J Biotechnol 163(2), 2013
PMID: 22982516
High-resolution detection of DNA binding sites of the global transcriptional regulator GlxR in Corynebacterium glutamicum.
Jungwirth B, Sala C, Kohl TA, Uplekar S, Baumbach J, Cole ST, Pühler A, Tauch A., Microbiology 159(pt 1), 2013
PMID: 23103979
Accelerated pentose utilization by Corynebacterium glutamicum for accelerated production of lysine, glutamate, ornithine and putrescine.
Meiswinkel TM, Gopinath V, Lindner SN, Nampoothiri KM, Wendisch VF., Microb Biotechnol 6(2), 2013
PMID: 23164409
Monitoring of population dynamics of Corynebacterium glutamicum by multiparameter flow cytometry.
Neumeyer A, Hübschmann T, Müller S, Frunzke J., Microb Biotechnol 6(2), 2013
PMID: 23279937
Adaptive evolution of Corynebacterium glutamicum resistant to oxidative stress and its global gene expression profiling.
Lee JY, Seo J, Kim ES, Lee HS, Kim P., Biotechnol Lett 35(5), 2013
PMID: 23288296
Transcriptional control of the F0F1-ATP synthase operon of Corynebacterium glutamicum: SigmaH factor binds to its promoter and regulates its expression at different pH values.
Barriuso-Iglesias M, Barreiro C, Sola-Landa A, Martín JF., Microb Biotechnol 6(2), 2013
PMID: 23298179
The pan-genome of the animal pathogen Corynebacterium pseudotuberculosis reveals differences in genome plasticity between the biovar ovis and equi strains.
Soares SC, Silva A, Trost E, Blom J, Ramos R, Carneiro A, Ali A, Santos AR, Pinto AC, Diniz C, Barbosa EG, Dorella FA, Aburjaile F, Rocha FS, Nascimento KK, Guimarães LC, Almeida S, Hassan SS, Bakhtiar SM, Pereira UP, Abreu VA, Schneider MP, Miyoshi A, Tauch A, Azevedo V., PLoS One 8(1), 2013
PMID: 23342011
Non-invasive online detection of microbial lysine formation in stirred tank bioreactors by using calorespirometry.
Regestein L, Maskow T, Tack A, Knabben I, Wunderlich M, Lerchner J, Büchs J., Biotechnol Bioeng 110(5), 2013
PMID: 23280310
Cell envelope of corynebacteria: structure and influence on pathogenicity.
Burkovski A., ISRN Microbiol 2013(), 2013
PMID: 23724339
GenR, an IclR-type regulator, activates and represses the transcription of gen genes involved in 3-hydroxybenzoate and gentisate catabolism in Corynebacterium glutamicum.
Chao H, Zhou NY., J Bacteriol 195(7), 2013
PMID: 23354754
Increasing l-isoleucine production in Corynebacterium glutamicum by overexpressing global regulator Lrp and two-component export system BrnFE.
Yin L, Shi F, Hu X, Chen C, Wang X., J Appl Microbiol 114(5), 2013
PMID: 23331988
Phosphotransferase system-mediated glucose uptake is repressed in phosphoglucoisomerase-deficient Corynebacterium glutamicum strains.
Lindner SN, Petrov DP, Hagmann CT, Henrich A, Krämer R, Eikmanns BJ, Wendisch VF, Seibold GM., Appl Environ Microbiol 79(8), 2013
PMID: 23396334
Involvement of regulatory interactions among global regulators GlxR, SugR, and RamA in expression of ramA in Corynebacterium glutamicum.
Toyoda K, Teramoto H, Gunji W, Inui M, Yukawa H., J Bacteriol 195(8), 2013
PMID: 23396909
Conversion of Corynebacterium glutamicum from an aerobic respiring to an aerobic fermenting bacterium by inactivation of the respiratory chain.
Koch-Koerfges A, Pfelzer N, Platzen L, Oldiges M, Bott M., Biochim Biophys Acta 1827(6), 2013
PMID: 23416842
Proteome turnover in bacteria: current status for Corynebacterium glutamicum and related bacteria.
Trötschel C, Albaum SP, Poetsch A., Microb Biotechnol 6(6), 2013
PMID: 23425033
Maltose uptake by the novel ABC transport system MusEFGK2I causes increased expression of ptsG in Corynebacterium glutamicum.
Henrich A, Kuhlmann N, Eck AW, Krämer R, Seibold GM., J Bacteriol 195(11), 2013
PMID: 23543710
The role of ARGR repressor regulation on L-arginine production in Corynebacterium crenatum.
Xu M, Rao Z, Dou W, Xu Z., Appl Biochem Biotechnol 170(3), 2013
PMID: 23564434
Proteome response of Corynebacterium glutamicum to high concentration of industrially relevant C₄ and C₅ dicarboxylic acids.
Vasco-Cárdenas MF, Baños S, Ramos A, Martín JF, Barreiro C., J Proteomics 85(), 2013
PMID: 23624027
Strain optimization for efficient isobutanol production using Corynebacterium glutamicum under oxygen deprivation.
Yamamoto S, Suda M, Niimi S, Inui M, Yukawa H., Biotechnol Bioeng 110(11), 2013
PMID: 23737329
Ornithine cyclodeaminase-based proline production by Corynebacterium glutamicum.
Jensen JV, Wendisch VF., Microb Cell Fact 12(), 2013
PMID: 23806148
Construction and application of an efficient multiple-gene-deletion system in Corynebacterium glutamicum.
Hu J, Tan Y, Li Y, Hu X, Xu D, Wang X., Plasmid 70(3), 2013
PMID: 23856168
Complex regulation of the phosphoenolpyruvate carboxykinase gene pck and characterization of its GntR-type regulator IolR as a repressor of myo-inositol utilization genes in Corynebacterium glutamicum.
Klaffl S, Brocker M, Kalinowski J, Eikmanns BJ, Bott M., J Bacteriol 195(18), 2013
PMID: 23873914
Construction of a prophage-free variant of Corynebacterium glutamicum ATCC 13032 for use as a platform strain for basic research and industrial biotechnology.
Baumgart M, Unthan S, Rückert C, Sivalingam J, Grünberger A, Kalinowski J, Bott M, Noack S, Frunzke J., Appl Environ Microbiol 79(19), 2013
PMID: 23892752
Enhancement of γ-aminobutyric acid production in recombinant Corynebacterium glutamicum by co-expressing two glutamate decarboxylase genes from Lactobacillus brevis.
Shi F, Jiang J, Li Y, Li Y, Xie Y., J Ind Microbiol Biotechnol 40(11), 2013
PMID: 23928903
Journal of Biotechnology opens the new section "Genome Announcement".
Puehler A., J Biotechnol 168(1), 2013
PMID: 23973871
Inactivation of the phosphoglucomutase gene pgm in Corynebacterium glutamicum affects cell shape and glycogen metabolism.
Seibold GM, Eikmanns BJ., Biosci Rep 33(4), 2013
PMID: 23863124
C1 metabolism in Corynebacterium glutamicum: an endogenous pathway for oxidation of methanol to carbon dioxide.
Witthoff S, Mühlroth A, Marienhagen J, Bott M., Appl Environ Microbiol 79(22), 2013
PMID: 24014532
Current knowledge on mycolic acids in Corynebacterium glutamicum and their relevance for biotechnological processes.
Lanéelle MA, Tropis M, Daffé M., Appl Microbiol Biotechnol 97(23), 2013
PMID: 24113823
A novel type of N-acetylglutamate synthase is involved in the first step of arginine biosynthesis in Corynebacterium glutamicum.
Petri K, Walter F, Persicke M, Rückert C, Kalinowski J., BMC Genomics 14(), 2013
PMID: 24138314
Comprehensive discovery and characterization of small RNAs in Corynebacterium glutamicum ATCC 13032.
Mentz A, Neshat A, Pfeifer-Sancar K, Pühler A, Rückert C, Kalinowski J., BMC Genomics 14(), 2013
PMID: 24138339
Systems metabolic engineering of Corynebacterium glutamicum for production of the chemical chaperone ectoine.
Becker J, Schäfer R, Kohlstedt M, Harder BJ, Borchert NS, Stöveken N, Bremer E, Wittmann C., Microb Cell Fact 12(), 2013
PMID: 24228689
Comprehensive analysis of the Corynebacterium glutamicum transcriptome using an improved RNAseq technique.
Pfeifer-Sancar K, Mentz A, Rückert C, Kalinowski J., BMC Genomics 14(), 2013
PMID: 24341750
Site-directed mutagenesis and feedback-resistant N-acetyl-L-glutamate kinase (NAGK) increase Corynebacterium crenatum L-arginine production.
Xu M, Rao Z, Dou W, Yang J, Jin J, Xu Z., Amino Acids 43(1), 2012
PMID: 21901472
Genome shuffling improves thermotolerance and glutamic acid production of Corynebacteria glutamicum.
Zheng P, Liu M, Liu XD, Du QY, Ni Y, Sun ZH., World J Microbiol Biotechnol 28(3), 2012
PMID: 22805825
Heterologous and homologous expression of the arginine biosynthetic argC~H cluster from Corynebacterium crenatum for improvement of (L) -arginine production.
Xu M, Rao Z, Yang J, Xia H, Dou W, Jin J, Xu Z., J Ind Microbiol Biotechnol 39(3), 2012
PMID: 22009057
Efficient aerobic succinate production from glucose in minimal medium with Corynebacterium glutamicum.
Litsanov B, Kabus A, Brocker M, Bott M., Microb Biotechnol 5(1), 2012
PMID: 22018023
Corynebacterium glutamicum as a potent biocatalyst for the bioconversion of pentose sugars to value-added products.
Gopinath V, Murali A, Dhar KS, Nampoothiri KM., Appl Microbiol Biotechnol 93(1), 2012
PMID: 22094976
Site-directed mutagenesis studies on the L-arginine-binding sites of feedback inhibition in N-acetyl-L-glutamate kinase (NAGK) from Corynebacterium glutamicum.
Xu M, Rao Z, Dou W, Jin J, Xu Z., Curr Microbiol 64(2), 2012
PMID: 22101454
Biochemical disclosure of the mycolate outer membrane of Corynebacterium glutamicum.
Marchand CH, Salmeron C, Bou Raad R, Méniche X, Chami M, Masi M, Blanot D, Daffé M, Tropis M, Huc E, Le Maréchal P, Decottignies P, Bayan N., J Bacteriol 194(3), 2012
PMID: 22123248
Bio-based production of chemicals, materials and fuels -Corynebacterium glutamicum as versatile cell factory.
Becker J, Wittmann C., Curr Opin Biotechnol 23(4), 2012
PMID: 22138494
Biotin protein ligase from Corynebacterium glutamicum: role for growth and L: -lysine production.
Peters-Wendisch P, Stansen KC, Götker S, Wendisch VF., Appl Microbiol Biotechnol 93(6), 2012
PMID: 22159614
Arabitol metabolism of Corynebacterium glutamicum and its regulation by AtlR.
Laslo T, von Zaluskowski P, Gabris C, Lodd E, Rückert C, Dangel P, Kalinowski J, Auchter M, Seibold G, Eikmanns BJ., J Bacteriol 194(5), 2012
PMID: 22178972
Corynebacterium glutamicum whcB, a stationary phase-specific regulatory gene.
Lee JY, Park JS, Kim HJ, Kim Y, Lee HS., FEMS Microbiol Lett 327(2), 2012
PMID: 22098456
A novel mycolic acid species defines two novel genera of the Actinobacteria, Hoyosella and Amycolicicoccus.
Lanéelle MA, Launay A, Spina L, Marrakchi H, Laval F, Eynard N, Lemassu A, Tropis M, Daffé M, Etienne G., Microbiology 158(pt 3), 2012
PMID: 22194354
Enzymatic synthesis of S-adenosylhomocysteine: immobilization of recombinant S-adenosylhomocysteine hydrolase from Corynebacterium glutamicum (ATCC 13032).
Lozada-Ramírez JD, Sánchez-Ferrer A, García-Carmona F., Appl Microbiol Biotechnol 93(6), 2012
PMID: 22202964
The gene encoding the alternative thymidylate synthase ThyX is regulated by sigma factor SigB in Corynebacterium glutamicum ATCC 13032.
Cho S, Yang S, Rhie H., FEMS Microbiol Lett 328(2), 2012
PMID: 22224900
Genome sequence of Corynebacterium glutamicum ATCC 14067, which provides insight into amino acid biosynthesis in coryneform bacteria.
Lv Y, Liao J, Wu Z, Han S, Lin Y, Zheng S., J Bacteriol 194(3), 2012
PMID: 22247536
Identification and characterization of γ-aminobutyric acid uptake system GabPCg (NCgl0464) in Corynebacterium glutamicum.
Zhao Z, Ding JY, Ma WH, Zhou NY, Liu SJ., Appl Environ Microbiol 78(8), 2012
PMID: 22307305
Genome-scale metabolic representation of Amycolatopsis balhimycina.
Vongsangnak W, Figueiredo LF, Förster J, Weber T, Thykaer J, Stegmann E, Wohlleben W, Nielsen J., Biotechnol Bioeng 109(7), 2012
PMID: 22252737
PIPS: pathogenicity island prediction software.
Soares SC, Abreu VA, Ramos RT, Cerdeira L, Silva A, Baumbach J, Trost E, Tauch A, Hirata R, Mattos-Guaraldi AL, Miyoshi A, Azevedo V., PLoS One 7(2), 2012
PMID: 22355329
Phylogenetic framework and molecular signatures for the main clades of the phylum Actinobacteria.
Gao B, Gupta RS., Microbiol Mol Biol Rev 76(1), 2012
PMID: 22390973
Genome shuffling improves thermotolerance and glutamic acid production of Corynebacteria glutamicum
Zheng P, Liu M, Liu Xd, Du Qy, Ni Y, Sun Zh., World J Microbiol Biotechnol 28(3), 2012
PMID: IND44746219
Toward homosuccinate fermentation: metabolic engineering of Corynebacterium glutamicum for anaerobic production of succinate from glucose and formate.
Litsanov B, Brocker M, Bott M., Appl Environ Microbiol 78(9), 2012
PMID: 22389371
Lactate utilization is regulated by the FadR-type regulator LldR in Pseudomonas aeruginosa.
Gao C, Hu C, Zheng Z, Ma C, Jiang T, Dou P, Zhang W, Che B, Wang Y, Lv M, Xu P., J Bacteriol 194(10), 2012
PMID: 22408166
Global proteome survey of protocatechuate- and glucose-grown Corynebacterium glutamicum reveals multiple physiological differences.
Haussmann U, Poetsch A., J Proteomics 75(9), 2012
PMID: 22450470
Improved L-lysine production with Corynebacterium glutamicum and systemic insight into citrate synthase flux and activity.
van Ooyen J, Noack S, Bott M, Reth A, Eggeling L., Biotechnol Bioeng 109(8), 2012
PMID: 22392073
The complete genome sequence of the acarbose producer Actinoplanes sp. SE50/110.
Schwientek P, Szczepanowski R, Rückert C, Kalinowski J, Klein A, Selber K, Wehmeier UF, Stoye J, Pühler A., BMC Genomics 13(), 2012
PMID: 22443545
Quantification of proteome dynamics in Corynebacterium glutamicum by (15)N-labeling and selected reaction monitoring.
Voges R, Noack S., J Proteomics 75(9), 2012
PMID: 22476105
Metabolic engineering and flux analysis of Corynebacterium glutamicum for L-serine production.
Lai S, Zhang Y, Liu S, Liang Y, Shang X, Chai X, Wen T., Sci China Life Sci 55(4), 2012
PMID: 22566084
Protein turnover quantification in a multilabeling approach: from data calculation to evaluation.
Trötschel C, Albaum SP, Wolff D, Schröder S, Goesmann A, Nattkemper TW, Poetsch A., Mol Cell Proteomics 11(8), 2012
PMID: 22493176
Pangenomic study of Corynebacterium diphtheriae that provides insights into the genomic diversity of pathogenic isolates from cases of classical diphtheria, endocarditis, and pneumonia.
Trost E, Blom J, Soares Sde C, Huang IH, Al-Dilaimi A, Schröder J, Jaenicke S, Dorella FA, Rocha FS, Miyoshi A, Azevedo V, Schneider MP, Silva A, Camello TC, Sabbadini PS, Santos CS, Santos LS, Hirata R, Mattos-Guaraldi AL, Efstratiou A, Schmitt MP, Ton-That H, Tauch A., J Bacteriol 194(12), 2012
PMID: 22505676
Purification and structural characterization of siderophore (corynebactin) from Corynebacterium diphtheriae.
Zajdowicz S, Haller JC, Krafft AE, Hunsucker SW, Mant CT, Duncan MW, Hodges RS, Jones DN, Holmes RK., PLoS One 7(4), 2012
PMID: 22514641
Two-component signal transduction in Corynebacterium glutamicum and other corynebacteria: on the way towards stimuli and targets.
Bott M, Brocker M., Appl Microbiol Biotechnol 94(5), 2012
PMID: 22539022
Degradation and assimilation of aromatic compounds by Corynebacterium glutamicum: another potential for applications for this bacterium?
Shen XH, Zhou NY, Liu SJ., Appl Microbiol Biotechnol 95(1), 2012
PMID: 22588501
Phenylacetic acid catabolism and its transcriptional regulation in Corynebacterium glutamicum.
Chen X, Kohl TA, Rückert C, Rodionov DA, Li LH, Ding JY, Kalinowski J, Liu SJ., Appl Environ Microbiol 78(16), 2012
PMID: 22685150
Corynebacterium glutamicum harbours a molybdenum cofactor-dependent formate dehydrogenase which alleviates growth inhibition in the presence of formate.
Witthoff S, Eggeling L, Bott M, Polen T., Microbiology 158(pt 9), 2012
PMID: 22767548
Postgenomic approaches to using corynebacteria as biocatalysts.
Vertès AA, Inui M, Yukawa H., Annu Rev Microbiol 66(), 2012
PMID: 22803796
Altered large-ring cyclodextrin product profile due to a mutation at Tyr-172 in the amylomaltase of Corynebacterium glutamicum.
Srisimarat W, Kaulpiboon J, Krusong K, Zimmermann W, Pongsawasdi P., Appl Environ Microbiol 78(20), 2012
PMID: 22865069
Transcriptional cross-regulation between Gram-negative and gram-positive bacteria, demonstrated using ArgP-argO of Escherichia coli and LysG-lysE of Corynebacterium glutamicum.
Marbaniang CN, Gowrishankar J., J Bacteriol 194(20), 2012
PMID: 22904281
Transcriptional regulation of the operon encoding stress-responsive ECF sigma factor SigH and its anti-sigma factor RshA, and control of its regulatory network in Corynebacterium glutamicum.
Busche T, Silar R, Pičmanová M, Pátek M, Kalinowski J., BMC Genomics 13(), 2012
PMID: 22943411
Complete genome sequence of Saccharothrix espanaensis DSM 44229(T) and comparison to the other completely sequenced Pseudonocardiaceae.
Strobel T, Al-Dilaimi A, Blom J, Gessner A, Kalinowski J, Luzhetska M, Pühler A, Szczepanowski R, Bechthold A, Rückert C., BMC Genomics 13(), 2012
PMID: 22958348
Carotenoid biosynthesis and overproduction in Corynebacterium glutamicum.
Heider SA, Peters-Wendisch P, Wendisch VF., BMC Microbiol 12(), 2012
PMID: 22963379
Sialic acid utilization by the soil bacterium Corynebacterium glutamicum.
Gruteser N, Marin K, Krämer R, Thomas GH., FEMS Microbiol Lett 336(2), 2012
PMID: 22924979
Coordinated regulation of gnd, which encodes 6-phosphogluconate dehydrogenase, by the two transcriptional regulators GntR1 and RamA in Corynebacterium glutamicum.
Tanaka Y, Ehira S, Teramoto H, Inui M, Yukawa H., J Bacteriol 194(23), 2012
PMID: 23024346
Next-generation sequencing-based genome-wide mutation analysis of L-lysine-producing Corynebacterium glutamicum ATCC 21300 strain.
Lee CS, Nam JY, Son ES, Kwon OC, Han W, Cho JY, Park YJ., J Microbiol 50(5), 2012
PMID: 23124757
The two-component system ChrSA is crucial for haem tolerance and interferes with HrrSA in haem-dependent gene regulation in Corynebacterium glutamicum.
Heyer A, Gätgens C, Hentschel E, Kalinowski J, Bott M, Frunzke J., Microbiology 158(pt 12), 2012
PMID: 23038807
Sugar transport systems in Corynebacterium glutamicum: features and applications to strain development.
Ikeda M., Appl Microbiol Biotechnol 96(5), 2012
PMID: 23081775
Metabolic engineering of Corynebacterium glutamicum aimed at alternative carbon sources and new products.
Zahoor A, Lindner SN, Wendisch VF., Comput Struct Biotechnol J 3(), 2012
PMID: 24688664
Corynebacterium glutamicum Zur acts as a zinc-sensing transcriptional repressor of both zinc-inducible and zinc-repressible genes involved in zinc homeostasis.
Teramoto H, Inui M, Yukawa H., FEBS J 279(23), 2012
PMID: 23061624
Analysis of in vivo function of predicted isoenzymes:a metabolomic approach.
Choorapoikayil S, Schoepe J, Buchinger S, Schomburg D., OMICS 16(12), 2012
PMID: 23215805
Genome sequence of the halotolerant bacterium Corynebacterium halotolerans type strain YIM 70093(T) (= DSM 44683(T)).
Rückert C, Albersmeier A, Al-Dilaimi A, Niehaus K, Szczepanowski R, Kalinowski J., Stand Genomic Sci 7(2), 2012
PMID: 23408721
Identification of the membrane protein SucE and its role in succinate transport in Corynebacterium glutamicum.
Huhn S, Jolkver E, Krämer R, Marin K., Appl Microbiol Biotechnol 89(2), 2011
PMID: 20809072
Positive transcriptional control of the pyridoxal phosphate biosynthesis genes pdxST by the MocR-type regulator PdxR of Corynebacterium glutamicum ATCC 13032.
Jochmann N, Götker S, Tauch A., Microbiology 157(pt 1), 2011
PMID: 20847010
Engineering of nitrogen metabolism and its regulation in Corynebacterium glutamicum: influence on amino acid pools and production.
Rehm N, Burkovski A., Appl Microbiol Biotechnol 89(2), 2011
PMID: 20922371
Multiple-genome comparison reveals new loci for Mycobacterium species identification.
Dai J, Chen Y, Dean S, Morris JG, Salfinger M, Johnson JA., J Clin Microbiol 49(1), 2011
PMID: 21048007
Identification of mannose uptake and catabolism genes in Corynebacterium glutamicum and genetic engineering for simultaneous utilization of mannose and glucose.
Sasaki M, Teramoto H, Inui M, Yukawa H., Appl Microbiol Biotechnol 89(6), 2011
PMID: 21125267
From zero to hero--design-based systems metabolic engineering of Corynebacterium glutamicum for L-lysine production.
Becker J, Zelder O, Häfner S, Schröder H, Wittmann C., Metab Eng 13(2), 2011
PMID: 21241816
Fatty acid biosynthesis in actinomycetes.
Gago G, Diacovich L, Arabolaza A, Tsai SC, Gramajo H., FEMS Microbiol Rev 35(3), 2011
PMID: 21204864
Control of adhA and sucR expression by the SucR regulator in Corynebacterium glutamicum.
Auchter M, Laslo T, Fleischer C, Schiller L, Arndt A, Gaigalat L, Kalinowski J, Eikmanns BJ., J Biotechnol 152(3), 2011
PMID: 21320555
Diversity of metabolic shift in response to oxygen deprivation in Corynebacterium glutamicum and its close relatives.
Yamamoto S, Sakai M, Inui M, Yukawa H., Appl Microbiol Biotechnol 90(3), 2011
PMID: 21327408
The ncgl1108 (PheP (Cg)) gene encodes a new L-Phe transporter in Corynebacterium glutamicum.
Zhao Z, Ding JY, Li T, Zhou NY, Liu SJ., Appl Microbiol Biotechnol 90(6), 2011
PMID: 21468701
Tools for genetic manipulations in Corynebacterium glutamicum and their applications.
Nešvera J, Pátek M., Appl Microbiol Biotechnol 90(5), 2011
PMID: 21519933
Purification and characterization of an arginine regulatory protein, ArgR, in Corynebacterium glutamicum.
Yim SH, Jung S, Lee SK, Cheon CI, Song E, Lee SS, Shin J, Lee MS., J Ind Microbiol Biotechnol 38(12), 2011
PMID: 21559975
Comparative metabolic capabilities for Micrococcus luteus NCTC 2665, the "Fleming" strain, and actinobacteria.
Rokem JS, Vongsangnak W, Nielsen J., Biotechnol Bioeng 108(11), 2011
PMID: 21618466
Proteomics of corynebacteria: From biotechnology workhorses to pathogens.
Poetsch A, Haussmann U, Burkovski A., Proteomics 11(15), 2011
PMID: 21674800
Genome sequence of Corynebacterium nuruki S6-4 T, isolated from alcohol fermentation starter.
Shin NR, Whon TW, Roh SW, Kim MS, Jung MJ, Lee J, Bae JW., J Bacteriol 193(16), 2011
PMID: 21685278
Diversity-oriented production of metabolites derived from chorismate and their use in organic synthesis.
Bongaerts J, Esser S, Lorbach V, Al-Momani L, Müller MA, Franke D, Grondal C, Kurutsch A, Bujnicki R, Takors R, Raeven L, Wubbolts M, Bovenberg R, Nieger M, Schürmann M, Trachtmann N, Kozak S, Sprenger GA, Müller M., Angew Chem Int Ed Engl 50(34), 2011
PMID: 21739551
Amino acid production from rice straw and wheat bran hydrolysates by recombinant pentose-utilizing Corynebacterium glutamicum.
Gopinath V, Meiswinkel TM, Wendisch VF, Nampoothiri KM., Appl Microbiol Biotechnol 92(5), 2011
PMID: 21796382
Synthesis of γ-aminobutyric acid by expressing Lactobacillus brevis-derived glutamate decarboxylase in the Corynebacterium glutamicum strain ATCC 13032.
Shi F, Li Y., Biotechnol Lett 33(12), 2011
PMID: 21826397
The glgB-encoded glycogen branching enzyme is essential for glycogen accumulation in Corynebacterium glutamicum.
Seibold GM, Breitinger KJ, Kempkes R, Both L, Krämer M, Dempf S, Eikmanns BJ., Microbiology 157(pt 11), 2011
PMID: 21903753
Deletion of the aconitase gene in Corynebacterium glutamicum causes strong selection pressure for secondary mutations inactivating citrate synthase.
Baumgart M, Mustafi N, Krug A, Bott M., J Bacteriol 193(24), 2011
PMID: 21984793
Growth independent rhamnolipid production from glucose using the non-pathogenic Pseudomonas putida KT2440.
Wittgens A, Tiso T, Arndt TT, Wenk P, Hemmerich J, Müller C, Wichmann R, Küpper B, Zwick M, Wilhelm S, Hausmann R, Syldatk C, Rosenau F, Blank LM., Microb Cell Fact 10(), 2011
PMID: 21999513
Genome sequence of Corynebacterium glutamicum S9114, a strain for industrial production of glutamate.
Lv Y, Wu Z, Han S, Lin Y, Zheng S., J Bacteriol 193(21), 2011
PMID: 21994927
Characterization of an adenylate cyclase gene (cyaB) deletion mutant of Corynebacterium glutamicum ATCC 13032.
Cha PH, Park SY, Moon MW, Subhadra B, Oh TK, Kim E, Kim JF, Lee JK., Appl Microbiol Biotechnol 85(4), 2010
PMID: 19568747
Recombinant organisms for production of industrial products.
Adrio JL, Demain AL., Bioeng Bugs 1(2), 2010
PMID: 21326937
Isolation, evaluation and use of two strong, carbon source-inducible promoters from Corynebacterium glutamicum.
Okibe N, Suzuki N, Inui M, Yukawa H., Lett Appl Microbiol 50(2), 2010
PMID: 20002569
Requirement of de novo synthesis of the OdhI protein in penicillin-induced glutamate production by Corynebacterium glutamicum.
Kim J, Fukuda H, Hirasawa T, Nagahisa K, Nagai K, Wachi M, Shimizu H., Appl Microbiol Biotechnol 86(3), 2010
PMID: 19956942
Reconstitution experiments and gene deletions reveal the existence of two-component major cell wall channels in the genus Corynebacterium.
Barth E, Barceló MA, Kläckta C, Benz R., J Bacteriol 192(3), 2010
PMID: 19966008
Xylitol production by recombinant Corynebacterium glutamicum under oxygen deprivation.
Sasaki M, Jojima T, Inui M, Yukawa H., Appl Microbiol Biotechnol 86(4), 2010
PMID: 20012280
Biotechnological production of enantiomeric pure lactic acid from renewable resources: recent achievements, perspectives, and limits.
Okano K, Tanaka T, Ogino C, Fukuda H, Kondo A., Appl Microbiol Biotechnol 85(3), 2010
PMID: 19826806
The Zur regulon of Corynebacterium glutamicum ATCC 13032.
Schröder J, Jochmann N, Rodionov DA, Tauch A., BMC Genomics 11(), 2010
PMID: 20055984
The transcriptional regulators RamA and RamB are involved in the regulation of glycogen synthesis in Corynebacterium glutamicum.
Seibold GM, Hagmann CT, Schietzel M, Emer D, Auchter M, Schreiner J, Eikmanns BJ., Microbiology 156(pt 4), 2010
PMID: 20056699
A novel redox-sensing transcriptional regulator CyeR controls expression of an Old Yellow Enzyme family protein in Corynebacterium glutamicum.
Ehira S, Teramoto H, Inui M, Yukawa H., Microbiology 156(pt 5), 2010
PMID: 20110293
Adaptation of Corynebacterium glutamicum to salt-stress conditions.
Fränzel B, Trötschel C, Rückert C, Kalinowski J, Poetsch A, Wolters DA., Proteomics 10(3), 2010
PMID: 19950167
Transcriptional regulation of histidine biosynthesis genes in Corynebacterium glutamicum.
Jung S, Chun JY, Yim SH, Lee SS, Cheon CI, Song E, Lee MS., Can J Microbiol 56(2), 2010
PMID: 20237580
Polyphosphate/ATP-dependent NAD kinase of Corynebacterium glutamicum: biochemical properties and impact of ppnK overexpression on lysine production.
Lindner SN, Niederholtmeyer H, Schmitz K, Schoberth SM, Wendisch VF., Appl Microbiol Biotechnol 87(2), 2010
PMID: 20180116
Division and cell envelope regulation by Ser/Thr phosphorylation: Mycobacterium shows the way.
Molle V, Kremer L., Mol Microbiol 75(5), 2010
PMID: 20487298
Carbohydrate metabolism in Corynebacterium glutamicum and applications for the metabolic engineering of L-lysine production strains.
Blombach B, Seibold GM., Appl Microbiol Biotechnol 86(5), 2010
PMID: 20333512
Transcriptional regulation of gene expression in Corynebacterium glutamicum: the role of global, master and local regulators in the modular and hierarchical gene regulatory network.
Schröder J, Tauch A., FEMS Microbiol Rev 34(5), 2010
PMID: 20491930
Rational design for over-production of desirable microbial metabolites by precision engineering.
Gao H, Zhou X, Gou Z, Zhuo Y, Fu C, Liu M, Song F, Ashforth E, Zhang L., Antonie Van Leeuwenhoek 98(2), 2010
PMID: 20401739
Codon Usage Patterns in Corynebacterium glutamicum: Mutational Bias, Natural Selection and Amino Acid Conservation.
Liu G, Wu J, Yang H, Bao Q., Comp Funct Genomics 2010(), 2010
PMID: 20445740
Penicillin-binding protein folding is dependent on the PrsA peptidyl-prolyl cis-trans isomerase in Bacillus subtilis.
Hyyryläinen HL, Marciniak BC, Dahncke K, Pietiäinen M, Courtin P, Vitikainen M, Seppala R, Otto A, Becher D, Chapot-Chartier MP, Kuipers OP, Kontinen VP., Mol Microbiol 77(1), 2010
PMID: 20487272
Utilization of phenol and naphthalene affects synthesis of various amino acids in Corynebacterium glutamicum.
Lee SY, Le TH, Chang ST, Park JS, Kim YH, Min J., Curr Microbiol 61(6), 2010
PMID: 20443004
OdhI dephosphorylation kinetics during different glutamate production processes involving Corynebacterium glutamicum.
Boulahya KA, Guedon E, Delaunay S, Schultz C, Boudrant J, Bott M, Goergen JL., Appl Microbiol Biotechnol 87(5), 2010
PMID: 20449744
Alternative thymidylate synthase, ThyX, involved in Corynebacterium glutamicum ATCC 13032 survival during stationary growth phase.
Park M, Cho S, Lee H, Sibley CH, Rhie H., FEMS Microbiol Lett 307(2), 2010
PMID: 20636973
Biofuel production improvement with genome-scale models: The role of cell composition.
Senger RS., Biotechnol J 5(7), 2010
PMID: 20540108
Regulation of the expression of genes involved in NAD de novo biosynthesis in Corynebacterium glutamicum.
Teramoto H, Suda M, Inui M, Yukawa H., Appl Environ Microbiol 76(16), 2010
PMID: 20601509
Phosphorylation of a novel cytoskeletal protein (RsmP) regulates rod-shaped morphology in Corynebacterium glutamicum.
Fiuza M, Letek M, Leiba J, Villadangos AF, Vaquera J, Zanella-Cléon I, Mateos LM, Molle V, Gil JA., J Biol Chem 285(38), 2010
PMID: 20622015
RosR (Cg1324), a hydrogen peroxide-sensitive MarR-type transcriptional regulator of Corynebacterium glutamicum.
Bussmann M, Baumgart M, Bott M., J Biol Chem 285(38), 2010
PMID: 20643656
L-Glutamine as a nitrogen source for Corynebacterium glutamicum: derepression of the AmtR regulon and implications for nitrogen sensing.
Rehm N, Georgi T, Hiery E, Degner U, Schmiedl A, Burkovski A, Bott M., Microbiology 156(pt 10), 2010
PMID: 20656783
Corynebacterium glutamicum exhibits a membrane-related response to a small ferrocene-conjugated antimicrobial peptide.
Fränzel B, Frese C, Penkova M, Metzler-Nolte N, Bandow JE, Wolters DA., J Biol Inorg Chem 15(8), 2010
PMID: 20658302
Multilocus sequence typing identifies evidence for recombination and two distinct lineages of Corynebacterium diphtheriae.
Bolt F, Cassiday P, Tondella ML, Dezoysa A, Efstratiou A, Sing A, Zasada A, Bernard K, Guiso N, Badell E, Rosso ML, Baldwin A, Dowson C., J Clin Microbiol 48(11), 2010
PMID: 20844217
The TetR-type transcriptional regulator FasR of Corynebacterium glutamicum controls genes of lipid synthesis during growth on acetate.
Nickel J, Irzik K, van Ooyen J, Eggeling L., Mol Microbiol 78(1), 2010
PMID: 20923423
Regulation of genes involved in sugar uptake, glycolysis and lactate production in Corynebacterium glutamicum.
Teramoto H, Inui M, Yukawa H., Future Microbiol 5(10), 2010
PMID: 21073308
Identification and quantification of mycothiol in Actinobacteria by a novel enzymatic method.
Yin YJ, Wang BJ, Jiang CY, Luo YM, Jin JH, Liu SJ., Appl Microbiol Biotechnol 88(6), 2010
PMID: 20922372
The arthrobacter arilaitensis Re117 genome sequence reveals its genetic adaptation to the surface of cheese.
Monnet C, Loux V, Gibrat JF, Spinnler E, Barbe V, Vacherie B, Gavory F, Gourbeyre E, Siguier P, Chandler M, Elleuch R, Irlinger F, Vallaeys T., PLoS One 5(11), 2010
PMID: 21124797
Quinone-dependent D-lactate dehydrogenase Dld (Cg1027) is essential for growth of Corynebacterium glutamicum on D-lactate.
Kato O, Youn JW, Stansen KC, Matsui D, Oikawa T, Wendisch VF., BMC Microbiol 10(), 2010
PMID: 21159175
Effect of odhA overexpression and odhA antisense RNA expression on Tween-40-triggered glutamate production by Corynebacterium glutamicum.
Kim J, Hirasawa T, Sato Y, Nagahisa K, Furusawa C, Shimizu H., Appl Microbiol Biotechnol 81(6), 2009
PMID: 18923827
A combination of metabolome and transcriptome analyses reveals new targets of the Corynebacterium glutamicum nitrogen regulator AmtR.
Buchinger S, Strösser J, Rehm N, Hänssler E, Hans S, Bathe B, Schomburg D, Krämer R, Burkovski A., J Biotechnol 140(1-2), 2009
PMID: 19041910
Dual transcriptional control of the acetaldehyde dehydrogenase gene ald of Corynebacterium glutamicum by RamA and RamB.
Auchter M, Arndt A, Eikmanns BJ., J Biotechnol 140(1-2), 2009
PMID: 19041911
Myo-inositol facilitators IolT1 and IolT2 enhance D-mannitol formation from D-fructose in Corynebacterium glutamicum.
Bäumchen C, Krings E, Bringer S, Eggeling L, Sahm H., FEMS Microbiol Lett 290(2), 2009
PMID: 19054080
Acetohydroxyacid synthase, a novel target for improvement of L-lysine production by Corynebacterium glutamicum.
Blombach B, Hans S, Bathe B, Eikmanns BJ., Appl Environ Microbiol 75(2), 2009
PMID: 19047397
TatABC overexpression improves Corynebacterium glutamicum Tat-dependent protein secretion.
Kikuchi Y, Itaya H, Date M, Matsui K, Wu LF., Appl Environ Microbiol 75(3), 2009
PMID: 19074606
Crystallization and preliminary crystallographic analysis of cgHle, a homoserine acetyltransferase homologue, from Corynebacterium glutamicum.
Tölzer C, Pal S, Watzlawick H, Altenbuchner J, Niefind K., Acta Crystallogr Sect F Struct Biol Cryst Commun 65(pt 1), 2009
PMID: 19153452
Pathway identification combining metabolic flux and functional genomics analyses: acetate and propionate activation by Corynebacterium glutamicum.
Veit A, Rittmann D, Georgi T, Youn JW, Eikmanns BJ, Wendisch VF., J Biotechnol 140(1-2), 2009
PMID: 19162097
Elastase digests: new ammunition for shotgun membrane proteomics.
Rietschel B, Arrey TN, Meyer B, Bornemann S, Schuerken M, Karas M, Poetsch A., Mol Cell Proteomics 8(5), 2009
PMID: 19116210
Characterization of the LacI-type transcriptional repressor RbsR controlling ribose transport in Corynebacterium glutamicum ATCC 13032.
Nentwich SS, Brinkrolf K, Gaigalat L, Hüser AT, Rey DA, Mohrbach T, Marin K, Pühler A, Tauch A, Kalinowski J., Microbiology 155(pt 1), 2009
PMID: 19118356
Integrated analysis and reconstruction of microbial transcriptional gene regulatory networks using CoryneRegNet.
Baumbach J, Wittkop T, Kleindt CK, Tauch A., Nat Protoc 4(6), 2009
PMID: 19498379
In silico genome-scale reconstruction and validation of the Corynebacterium glutamicum metabolic network.
Kjeldsen KR, Nielsen J., Biotechnol Bioeng 102(2), 2009
PMID: 18985611
Roles of maltodextrin and glycogen phosphorylases in maltose utilization and glycogen metabolism in Corynebacterium glutamicum.
Seibold GM, Wurst M, Eikmanns BJ., Microbiology 155(pt 2), 2009
PMID: 19202084
Microarray studies reveal a 'differential response' to moderate or severe heat shock of the HrcA- and HspR-dependent systems in Corynebacterium glutamicum.
Barreiro C, Nakunst D, Hüser AT, de Paz HD, Kalinowski J, Martín JF., Microbiology 155(pt 2), 2009
PMID: 19202085
Formation and metabolism of methylmalonyl coenzyme A in Corynebacterium glutamicum.
Botella L, Lindley ND, Eggeling L., J Bacteriol 191(8), 2009
PMID: 19233926
Regulation of Corynebacterium glutamicum heat shock response by the extracytoplasmic-function sigma factor SigH and transcriptional regulators HspR and HrcA.
Ehira S, Teramoto H, Inui M, Yukawa H., J Bacteriol 191(9), 2009
PMID: 19270092
Potassium transport in corynebacterium glutamicum is facilitated by the putative channel protein CglK, which is essential for pH homeostasis and growth at acidic pH.
Follmann M, Becker M, Ochrombel I, Ott V, Krämer R, Marin K., J Bacteriol 191(9), 2009
PMID: 19270097
Arsenate reductase, mycothiol, and mycoredoxin concert thiol/disulfide exchange.
Ordóñez E, Van Belle K, Roos G, De Galan S, Letek M, Gil JA, Wyns L, Mateos LM, Messens J., J Biol Chem 284(22), 2009
PMID: 19286650
Exopolyphosphatases PPX1 and PPX2 from Corynebacterium glutamicum.
Lindner SN, Knebel S, Wesseling H, Schoberth SM, Wendisch VF., Appl Environ Microbiol 75(10), 2009
PMID: 19304823
The two-phase partitioning system--a powerful technique to purify integral membrane proteins of Corynebacterium glutamicum for quantitative shotgun analysis.
Fränzel B, Fischer F, Trötschel C, Poetsch A, Wolters D., Proteomics 9(8), 2009
PMID: 19322788
Regulation of ldh expression during biotin-limited growth of Corynebacterium glutamicum.
Dietrich C, Nato A, Bost B, Le Maréchal P, Guyonvarch A., Microbiology 155(pt 4), 2009
PMID: 19332837
Dynamic and structural characterization of a bacterial FHA protein reveals a new autoinhibition mechanism.
Barthe P, Roumestand C, Canova MJ, Kremer L, Hurard C, Molle V, Cohen-Gonsaud M., Structure 17(4), 2009
PMID: 19368890
Identification and functional analysis of the gene cluster for L-arabinose utilization in Corynebacterium glutamicum.
Kawaguchi H, Sasaki M, Vertès AA, Inui M, Yukawa H., Appl Environ Microbiol 75(11), 2009
PMID: 19346355
Genetic makeup of the Corynebacterium glutamicum LexA regulon deduced from comparative transcriptomics and in vitro DNA band shift assays.
Jochmann N, Kurze AK, Czaja LF, Brinkrolf K, Brune I, Hüser AT, Hansmeier N, Pühler A, Borovok I, Tauch A., Microbiology 155(pt 5), 2009
PMID: 19372162
Citrate utilization by Corynebacterium glutamicum is controlled by the CitAB two-component system through positive regulation of the citrate transport genes citH and tctCBA.
Brocker M, Schaffer S, Mack C, Bott M., J Bacteriol 191(12), 2009
PMID: 19376865
Regulation of expression of genes involved in quinate and shikimate utilization in Corynebacterium glutamicum.
Teramoto H, Inui M, Yukawa H., Appl Environ Microbiol 75(11), 2009
PMID: 19376919
A game with many players: control of gdh transcription in Corynebacterium glutamicum.
Hänssler E, Müller T, Palumbo K, Patek M, Brocker M, Krämer R, Burkovski A., J Biotechnol 142(2), 2009
PMID: 19394370
Engineering of pentose transport in Corynebacterium glutamicum to improve simultaneous utilization of mixed sugars.
Sasaki M, Jojima T, Kawaguchi H, Inui M, Yukawa H., Appl Microbiol Biotechnol 85(1), 2009
PMID: 19529932
Physiological adaptation of Corynebacterium glutamicum to benzoate as alternative carbon source - a membrane proteome-centric view.
Haussmann U, Qi SW, Wolters D, Rögner M, Liu SJ, Poetsch A., Proteomics 9(14), 2009
PMID: 19639586
Characterization of the dicarboxylate transporter DctA in Corynebacterium glutamicum.
Youn JW, Jolkver E, Krämer R, Marin K, Wendisch VF., J Bacteriol 191(17), 2009
PMID: 19581365
Identification of a second beta-glucoside phosphoenolpyruvate: carbohydrate phosphotransferase system in Corynebacterium glutamicum R.
Tanaka Y, Teramoto H, Inui M, Yukawa H., Microbiology 155(pt 11), 2009
PMID: 19628558
Development and experimental verification of a genome-scale metabolic model for Corynebacterium glutamicum.
Shinfuku Y, Sorpitiporn N, Sono M, Furusawa C, Hirasawa T, Shimizu H., Microb Cell Fact 8(), 2009
PMID: 19646286
The GlxR regulon of the amino acid producer Corynebacterium glutamicum: Detection of the corynebacterial core regulon and integration into the transcriptional regulatory network model.
Kohl TA, Tauch A., J Biotechnol 143(4), 2009
PMID: 19665500
Electron paramagnetic resonance (EPR) spectroscopy of the stable-free radical in the native metallo-cofactor of the manganese-ribonucleotide reductase (Mn-RNR) of Corynebacterium glutamicum.
Abbouni B, Oehlmann W, Stolle P, Pierik AJ, Auling G., Free Radic Res 43(10), 2009
PMID: 19707921
Visualizing post genomics data-sets on customized pathway maps by ProMeTra-aeration-dependent gene expression and metabolism of Corynebacterium glutamicum as an example.
Neuweger H, Persicke M, Albaum SP, Bekel T, Dondrup M, Hüser AT, Winnebald J, Schneider J, Kalinowski J, Goesmann A., BMC Syst Biol 3(), 2009
PMID: 19698148
Genomic basis for natural product biosynthetic diversity in the actinomycetes.
Nett M, Ikeda H, Moore BS., Nat Prod Rep 26(11), 2009
PMID: 19844637
Genetic and biochemical analysis of the serine/threonine protein kinases PknA, PknB, PknG and PknL of Corynebacterium glutamicum: evidence for non-essentiality and for phosphorylation of OdhI and FtsZ by multiple kinases.
Schultz C, Niebisch A, Schwaiger A, Viets U, Metzger S, Bramkamp M, Bott M., Mol Microbiol 74(3), 2009
PMID: 19788543
Computing the shortest elementary flux modes in genome-scale metabolic networks.
de Figueiredo LF, Podhorski A, Rubio A, Kaleta C, Beasley JE, Schuster S, Planes FJ., Bioinformatics 25(23), 2009
PMID: 19793869
Qupe--a Rich Internet Application to take a step forward in the analysis of mass spectrometry-based quantitative proteomics experiments.
Albaum SP, Neuweger H, Fränzel B, Lange S, Mertens D, Trötschel C, Wolters D, Kalinowski J, Nattkemper TW, Goesmann A., Bioinformatics 25(23), 2009
PMID: 19808875
Functional genomics of pH homeostasis in Corynebacterium glutamicum revealed novel links between pH response, oxidative stress, iron homeostasis and methionine synthesis.
Follmann M, Ochrombel I, Krämer R, Trötschel C, Poetsch A, Rückert C, Hüser A, Persicke M, Seiferling D, Kalinowski J, Marin K., BMC Genomics 10(), 2009
PMID: 20025733
Engineering of an L-arabinose metabolic pathway in Corynebacterium glutamicum.
Kawaguchi H, Sasaki M, Vertès AA, Inui M, Yukawa H., Appl Microbiol Biotechnol 77(5), 2008
PMID: 17965859
Co-ordinated regulation of gluconate catabolism and glucose uptake in Corynebacterium glutamicum by two functionally equivalent transcriptional regulators, GntR1 and GntR2.
Frunzke J, Engels V, Hasenbein S, Gätgens C, Bott M., Mol Microbiol 67(2), 2008
PMID: 18047570
Production of Chryseobacterium proteolyticum protein-glutaminase using the twin-arginine translocation pathway in Corynebacterium glutamicum.
Kikuchi Y, Itaya H, Date M, Matsui K, Wu LF., Appl Microbiol Biotechnol 78(1), 2008
PMID: 18064454
Changes in enzyme activities at the pyruvate node in glutamate-overproducing Corynebacterium glutamicum.
Hasegawa T, Hashimoto K, Kawasaki H, Nakamatsu T., J Biosci Bioeng 105(1), 2008
PMID: 18295714
Secretion of Streptomyces mobaraensis pro-transglutaminase by coryneform bacteria.
Itaya H, Kikuchi Y., Appl Microbiol Biotechnol 78(4), 2008
PMID: 18219481
Cell growth and cell division in the rod-shaped actinomycete Corynebacterium glutamicum.
Letek M, Fiuza M, Ordóñez E, Villadangos AF, Ramos A, Mateos LM, Gil JA., Antonie Van Leeuwenhoek 94(1), 2008
PMID: 18283557
DivIVA is required for polar growth in the MreB-lacking rod-shaped actinomycete Corynebacterium glutamicum.
Letek M, Ordóñez E, Vaquera J, Margolin W, Flärdh K, Mateos LM, Gil JA., J Bacteriol 190(9), 2008
PMID: 18296522
NMR structure of protein Cgl2762 from Corynebacterium glutamicum implicated in DNA transposition reveals a helix-turn-helix motif attached to a flexibly disordered leucine zipper.
Singarapu KK, Xiao R, Sukumaran DK, Acton T, Montelione GT, Szyperski T., Proteins 70(4), 2008
PMID: 18175328
Corynebacterium glutamicum sigmaE is involved in responses to cell surface stresses and its activity is controlled by the anti-sigma factor CseE.
Park SD, Youn JW, Kim YJ, Lee SM, Kim Y, Lee HS., Microbiology 154(pt 3), 2008
PMID: 18310037
The lifestyle of Corynebacterium urealyticum derived from its complete genome sequence established by pyrosequencing.
Tauch A, Trost E, Tilker A, Ludewig U, Schneiker S, Goesmann A, Arnold W, Bekel T, Brinkrolf K, Brune I, Götker S, Kalinowski J, Kamp PB, Lobo FP, Viehoever P, Weisshaar B, Soriano F, Dröge M, Pühler A., J Biotechnol 136(1-2), 2008
PMID: 18367281
Ultrafast pyrosequencing of Corynebacterium kroppenstedtii DSM44385 revealed insights into the physiology of a lipophilic corynebacterium that lacks mycolic acids.
Tauch A, Schneider J, Szczepanowski R, Tilker A, Viehoever P, Gartemann KH, Arnold W, Blom J, Brinkrolf K, Brune I, Götker S, Weisshaar B, Goesmann A, Dröge M, Pühler A., J Biotechnol 136(1-2), 2008
PMID: 18430482
Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.
Ohnishi Y, Ishikawa J, Hara H, Suzuki H, Ikenoya M, Ikeda H, Yamashita A, Hattori M, Horinouchi S., J Bacteriol 190(11), 2008
PMID: 18375553
The LacI/GalR family transcriptional regulator UriR negatively controls uridine utilization of Corynebacterium glutamicum by binding to catabolite-responsive element (cre)-like sequences.
Brinkrolf K, Plöger S, Solle S, Brune I, Nentwich SS, Hüser AT, Kalinowski J, Pühler A, Tauch A., Microbiology 154(pt 4), 2008
PMID: 18375800
Population Heterogeneity in Corynebacterium glutamicum ATCC 13032 caused by prophage CGP3.
Frunzke J, Bramkamp M, Schweitzer JE, Bott M., J Bacteriol 190(14), 2008
PMID: 18487330
The GlxR regulon of the amino acid producer Corynebacterium glutamicum: in silico and in vitro detection of DNA binding sites of a global transcription regulator.
Kohl TA, Baumbach J, Jungwirth B, Pühler A, Tauch A., J Biotechnol 135(4), 2008
PMID: 18573287
Group 2 sigma factor SigB of Corynebacterium glutamicum positively regulates glucose metabolism under conditions of oxygen deprivation.
Ehira S, Shirai T, Teramoto H, Inui M, Yukawa H., Appl Environ Microbiol 74(16), 2008
PMID: 18567683
Identification of a gene encoding a transporter essential for utilization of C4 dicarboxylates in Corynebacterium glutamicum.
Teramoto H, Shirai T, Inui M, Yukawa H., Appl Environ Microbiol 74(17), 2008
PMID: 18586971
Distinct roles of two anaplerotic pathways in glutamate production induced by biotin limitation in Corynebacterium glutamicum.
Sato H, Orishimo K, Shirai T, Hirasawa T, Nagahisa K, Shimizu H, Wachi M., J Biosci Bioeng 106(1), 2008
PMID: 18691531
Metabolic regulation and overproduction of primary metabolites.
Sanchez S, Demain AL., Microb Biotechnol 1(4), 2008
PMID: 21261849
Genome sequence of the lytic bacteriophage P1201 from Corynebacterium glutamicum NCHU 87078: evolutionary relationships to phages from Corynebacterineae.
Chen CL, Pan TY, Kan SC, Kuan YC, Hong LY, Chiu KR, Sheu CS, Yang JS, Hsu WH, Hu HY., Virology 378(2), 2008
PMID: 18599103
Corynebacterium glutamicum contains 3-deoxy-D-arabino-heptulosonate 7-phosphate synthases that display novel biochemical features.
Liu YJ, Li PP, Zhao KX, Wang BJ, Jiang CY, Drake HL, Liu SJ., Appl Environ Microbiol 74(17), 2008
PMID: 18621870
Identification and characterization of the dicarboxylate uptake system DccT in Corynebacterium glutamicum.
Youn JW, Jolkver E, Krämer R, Marin K, Wendisch VF., J Bacteriol 190(19), 2008
PMID: 18658264
Engineering of a glycerol utilization pathway for amino acid production by Corynebacterium glutamicum.
Rittmann D, Lindner SN, Wendisch VF., Appl Environ Microbiol 74(20), 2008
PMID: 18757581
Biosynthesis and functions of mycothiol, the unique protective thiol of Actinobacteria.
Newton GL, Buchmeier N, Fahey RC., Microbiol Mol Biol Rev 72(3), 2008
PMID: 18772286
An efficient succinic acid production process in a metabolically engineered Corynebacterium glutamicum strain.
Okino S, Noburyu R, Suda M, Jojima T, Inui M, Yukawa H., Appl Microbiol Biotechnol 81(3), 2008
PMID: 18777022
Effect of carbon source availability and growth phase on expression of Corynebacterium glutamicum genes involved in the tricarboxylic acid cycle and glyoxylate bypass.
Han SO, Inui M, Yukawa H., Microbiology 154(pt 10), 2008
PMID: 18832313
The global repressor SugR controls expression of genes of glycolysis and of the L-lactate dehydrogenase LdhA in Corynebacterium glutamicum.
Engels V, Lindner SN, Wendisch VF., J Bacteriol 190(24), 2008
PMID: 18849435
Structural and functional characterization of the LldR from Corynebacterium glutamicum: a transcriptional repressor involved in L-lactate and sugar utilization.
Gao YG, Suzuki H, Itou H, Zhou Y, Tanaka Y, Wachi M, Watanabe N, Tanaka I, Yao M., Nucleic Acids Res 36(22), 2008
PMID: 18988622
A proteome analysis of the cadmium and mercury response in Corynebacterium glutamicum.
Fanous A, Weiss W, Görg A, Jacob F, Parlar H., Proteomics 8(23-24), 2008
PMID: 18972541
Response of the cytoplasmic and membrane proteome of Corynebacterium glutamicum ATCC 13032 to pH changes.
Barriuso-Iglesias M, Schluesener D, Barreiro C, Poetsch A, Martín JF., BMC Microbiol 8(), 2008
PMID: 19091079
Determination of metabolic flux changes during fed-batch cultivation from measurements of intracellular amino acids by LC-MS/MS.
Iwatani S, Van Dien S, Shimbo K, Kubota K, Kageyama N, Iwahata D, Miyano H, Hirayama K, Usuda Y, Shimizu K, Matsui K., J Biotechnol 128(1), 2007
PMID: 17055605
Topology and mutational analysis of the single Emb arabinofuranosyltransferase of Corynebacterium glutamicum as a model of Emb proteins of Mycobacterium tuberculosis.
Seidel M, Alderwick LJ, Sahm H, Besra GS, Eggeling L., Glycobiology 17(2), 2007
PMID: 17088267
RamB, the transcriptional regulator of acetate metabolism in Corynebacterium glutamicum, is subject to regulation by RamA and RamB.
Cramer A, Auchter M, Frunzke J, Bott M, Eikmanns BJ., J Bacteriol 189(3), 2007
PMID: 17114251
Role of cytochrome bd oxidase from Corynebacterium glutamicum in growth and lysine production.
Kabus A, Niebisch A, Bott M., Appl Environ Microbiol 73(3), 2007
PMID: 17142369
Engineering primary metabolic pathways of industrial micro-organisms.
Kern A, Tilley E, Hunter IS, Legisa M, Glieder A., J Biotechnol 129(1), 2007
PMID: 17196287
Bacteriophage-based vectors for site-specific insertion of DNA in the chromosome of Corynebacteria.
Oram M, Woolston JE, Jacobson AD, Holmes RK, Oram DM., Gene 391(1-2), 2007
PMID: 17275217
The transcriptional regulatory network of the amino acid producer Corynebacterium glutamicum.
Brinkrolf K, Brune I, Tauch A., J Biotechnol 129(2), 2007
PMID: 17227685
The phosphotransferase system of Corynebacterium glutamicum: features of sugar transport and carbon regulation.
Moon MW, Park SY, Choi SK, Lee JK., J Mol Microbiol Biotechnol 12(1-2), 2007
PMID: 17183210
Nitrogen metabolism and nitrogen control in corynebacteria: variations of a common theme.
Walter B, Hänssler E, Kalinowski J, Burkovski A., J Mol Microbiol Biotechnol 12(1-2), 2007
PMID: 17183220
The alternative sigma factor SigB of Corynebacterium glutamicum modulates global gene expression during transition from exponential growth to stationary phase.
Larisch C, Nakunst D, Hüser AT, Tauch A, Kalinowski J., BMC Genomics 8(), 2007
PMID: 17204139
Production of L-Lysine from starch by Corynebacterium glutamicum displaying alpha-amylase on its cell surface.
Tateno T, Fukuda H, Kondo A., Appl Microbiol Biotechnol 74(6), 2007
PMID: 17216452
Bacillus methanolicus: a candidate for industrial production of amino acids from methanol at 50 degrees C.
Brautaset T, Jakobsen ØM, Josefsen KD, Flickinger MC, Ellingsen TE., Appl Microbiol Biotechnol 74(1), 2007
PMID: 17216461
Random segment deletion based on IS31831 and Cre/loxP excision system in Corynebacterium glutamicum.
Tsuge Y, Suzuki N, Inui M, Yukawa H., Appl Microbiol Biotechnol 74(6), 2007
PMID: 17221197
Evaluation of two proteomics technologies used to screen the membrane proteomes of wild-type Corynebacterium glutamicum and an L-lysine-producing strain.
Schluesener D, Rögner M, Poetsch A., Anal Bioanal Chem 389(4), 2007
PMID: 17221235
Probing the heat shock response of Corynebacterium pseudotuberculosis: the major virulence factor, phospholipase D, is downregulated at 43 degrees C.
McKean SC, Davies JK, Moore RJ., Res Microbiol 158(3), 2007
PMID: 17320354
A proteomic study of Corynebacterium glutamicum AAA+ protease FtsH.
Lüdke A, Krämer R, Burkovski A, Schluesener D, Poetsch A., BMC Microbiol 7(), 2007
PMID: 17254330
The IclR-type transcriptional repressor LtbR regulates the expression of leucine and tryptophan biosynthesis genes in the amino acid producer Corynebacterium glutamicum.
Brune I, Jochmann N, Brinkrolf K, Hüser AT, Gerstmeir R, Eikmanns BJ, Kalinowski J, Pühler A, Tauch A., J Bacteriol 189(7), 2007
PMID: 17259312
The role of laterally transferred genes in adaptive evolution.
Marri PR, Hao W, Golding GB., BMC Evol Biol 7 Suppl 1(), 2007
PMID: 17288581
The DeoR-type regulator SugR represses expression of ptsG in Corynebacterium glutamicum.
Engels V, Wendisch VF., J Bacteriol 189(8), 2007
PMID: 17293426
Systems biology for industrial strains and fermentation processes--example: amino acids.
Takors R, Bathe B, Rieping M, Hans S, Kelle R, Huthmacher K., J Biotechnol 129(2), 2007
PMID: 17367886
Topological bias in distance-based phylogenetic methods: problems with over- and underestimated genetic distances.
Xia X., Evol Bioinform Online 2(), 2007
PMID: 19455228
Anaerobic growth of Corynebacterium glutamicum using nitrate as a terminal electron acceptor.
Nishimura T, Vertès AA, Shinoda Y, Inui M, Yukawa H., Appl Microbiol Biotechnol 75(4), 2007
PMID: 17347820
Improving lysine production by Corynebacterium glutamicum through DNA microarray-based identification of novel target genes.
Sindelar G, Wendisch VF., Appl Microbiol Biotechnol 76(3), 2007
PMID: 17364200
Glutamate production by Corynebacterium glutamicum: dependence on the oxoglutarate dehydrogenase inhibitor protein OdhI and protein kinase PknG.
Schultz C, Niebisch A, Gebel L, Bott M., Appl Microbiol Biotechnol 76(3), 2007
PMID: 17437098
The two carboxylases of Corynebacterium glutamicum essential for fatty acid and mycolic acid synthesis.
Gande R, Dover LG, Krumbach K, Besra GS, Sahm H, Oikawa T, Eggeling L., J Bacteriol 189(14), 2007
PMID: 17483212
The extracytoplasmic function-type sigma factor SigM of Corynebacterium glutamicum ATCC 13032 is involved in transcription of disulfide stress-related genes.
Nakunst D, Larisch C, Hüser AT, Tauch A, Pühler A, Kalinowski J., J Bacteriol 189(13), 2007
PMID: 17483229
FarR, a putative regulator of amino acid metabolism in Corynebacterium glutamicum.
Hänssler E, Müller T, Jessberger N, Völzke A, Plassmeier J, Kalinowski J, Krämer R, Burkovski A., Appl Microbiol Biotechnol 76(3), 2007
PMID: 17483938
Investigation of central carbon metabolism and the 2-methylcitrate cycle in Corynebacterium glutamicum by metabolic profiling using gas chromatography-mass spectrometry.
Plassmeier J, Barsch A, Persicke M, Niehaus K, Kalinowski J., J Biotechnol 130(4), 2007
PMID: 17586079
Polyketide synthases and nonribosomal peptide synthetases: the emerging view from bacterial genomics.
Donadio S, Monciardini P, Sosio M., Nat Prod Rep 24(5), 2007
PMID: 17898898
Gene expression analysis of Corynebacterium glutamicum subjected to long-term lactic acid adaptation.
Jakob K, Satorhelyi P, Lange C, Wendisch VF, Silakowski B, Scherer S, Neuhaus K., J Bacteriol 189(15), 2007
PMID: 17526706
Transcriptionally regulated adhA gene encodes alcohol dehydrogenase required for ethanol and n-propanol utilization in Corynebacterium glutamicum R.
Kotrbova-Kozak A, Kotrba P, Inui M, Sajdok J, Yukawa H., Appl Microbiol Biotechnol 76(6), 2007
PMID: 17646983
The three tricarboxylate synthase activities of Corynebacterium glutamicum and increase of L-lysine synthesis.
Radmacher E, Eggeling L., Appl Microbiol Biotechnol 76(3), 2007
PMID: 17653710
The alcohol dehydrogenase gene adhA in Corynebacterium glutamicum is subject to carbon catabolite repression.
Arndt A, Eikmanns BJ., J Bacteriol 189(20), 2007
PMID: 17693518
Offering surprises: TCA cycle regulation in Corynebacterium glutamicum.
Bott M., Trends Microbiol 15(9), 2007
PMID: 17764950
Genomics of Actinobacteria: tracing the evolutionary history of an ancient phylum.
Ventura M, Canchaya C, Tauch A, Chandra G, Fitzgerald GF, Chater KF, van Sinderen D., Microbiol Mol Biol Rev 71(3), 2007
PMID: 17804669
Site-directed integration system using a combination of mutant lox sites for Corynebacterium glutamicum.
Suzuki N, Inui M, Yukawa H., Appl Microbiol Biotechnol 77(4), 2007
PMID: 17938910
The DeoR-type transcriptional regulator SugR acts as a repressor for genes encoding the phosphoenolpyruvate:sugar phosphotransferase system (PTS) in Corynebacterium glutamicum.
Gaigalat L, Schlüter JP, Hartmann M, Mormann S, Tauch A, Pühler A, Kalinowski J., BMC Mol Biol 8(), 2007
PMID: 18005413
CoryneCenter - an online resource for the integrated analysis of corynebacterial genome and transcriptome data.
Neuweger H, Baumbach J, Albaum S, Bekel T, Dondrup M, Hüser AT, Kalinowski J, Oehm S, Pühler A, Rahmann S, Weile J, Goesmann A., BMC Syst Biol 1(), 2007
PMID: 18034885
Toward the complete membrane proteome: high coverage of integral membrane proteins through transmembrane peptide detection.
Fischer F, Wolters D, Rögner M, Poetsch A., Mol Cell Proteomics 5(3), 2006
PMID: 16291997
Towards bacterial strains overproducing L-tryptophan and other aromatics by metabolic engineering.
Ikeda M., Appl Microbiol Biotechnol 69(6), 2006
PMID: 16374633
The cytosolic, cell surface and extracellular proteomes of the biotechnologically important soil bacterium Corynebacterium efficiens YS-314 in comparison to those of Corynebacterium glutamicum ATCC 13032.
Hansmeier N, Chao TC, Pühler A, Tauch A, Kalinowski J., Proteomics 6(1), 2006
PMID: 16302278
Characterization and use of catabolite-repressed promoters from gluconate genes in Corynebacterium glutamicum.
Letek M, Valbuena N, Ramos A, Ordóñez E, Gil JA, Mateos LM., J Bacteriol 188(2), 2006
PMID: 16385030
Two-component systems of Corynebacterium glutamicum: deletion analysis and involvement of the PhoS-PhoR system in the phosphate starvation response.
Kocan M, Schaffer S, Ishige T, Sorger-Herrmann U, Wendisch VF, Bott M., J Bacteriol 188(2), 2006
PMID: 16385062
Biochemical and structural characterization of an essential acyl coenzyme A carboxylase from Mycobacterium tuberculosis.
Gago G, Kurth D, Diacovich L, Tsai SC, Gramajo H., J Bacteriol 188(2), 2006
PMID: 16385038
Emerging Corynebacterium glutamicum systems biology.
Wendisch VF, Bott M, Kalinowski J, Oldiges M, Wiechert W., J Biotechnol 124(1), 2006
PMID: 16406159
Prediction of the functional class of lipid binding proteins from sequence-derived properties irrespective of sequence similarity.
Lin HH, Han LY, Zhang HL, Zheng CJ, Xie B, Chen YZ., J Lipid Res 47(4), 2006
PMID: 16443826
Pyruvate:quinone oxidoreductase in Corynebacterium glutamicum: molecular analysis of the pqo gene, significance of the enzyme, and phylogenetic aspects.
Schreiner ME, Riedel C, Holátko J, Pátek M, Eikmanns BJ., J Bacteriol 188(4), 2006
PMID: 16452416
Complete nucleotide sequence and genome analysis of bacteriophage BFK20--a lytic phage of the industrial producer Brevibacterium flavum.
Bukovska G, Klucar L, Vlcek C, Adamovic J, Turna J, Timko J., Virology 348(1), 2006
PMID: 16457869
The DtxR protein acting as dual transcriptional regulator directs a global regulatory network involved in iron metabolism of Corynebacterium glutamicum.
Brune I, Werner H, Hüser AT, Kalinowski J, Pühler A, Tauch A., BMC Genomics 7(), 2006
PMID: 16469103
CoryneRegNet: an ontology-based data warehouse of corynebacterial transcription factors and regulatory networks.
Baumbach J, Brinkrolf K, Czaja LF, Rahmann S, Tauch A., BMC Genomics 7(), 2006
PMID: 16478536
Utilization of soluble starch by a recombinant Corynebacterium glutamicum strain: growth and lysine production.
Seibold G, Auchter M, Berens S, Kalinowski J, Eikmanns BJ., J Biotechnol 124(2), 2006
PMID: 16488498
A genome-based approach to create a minimally mutated Corynebacterium glutamicum strain for efficient L-lysine production.
Ikeda M, Ohnishi J, Hayashi M, Mitsuhashi S., J Ind Microbiol Biotechnol 33(7), 2006
PMID: 16506038
Mapping and comprehensive analysis of the extracellular and cell surface proteome of the human pathogen Corynebacterium diphtheriae.
Hansmeier N, Chao TC, Kalinowski J, Pühler A, Tauch A., Proteomics 6(8), 2006
PMID: 16544277
Identification of RamA, a novel LuxR-type transcriptional regulator of genes involved in acetate metabolism of Corynebacterium glutamicum.
Cramer A, Gerstmeir R, Schaffer S, Bott M, Eikmanns BJ., J Bacteriol 188(7), 2006
PMID: 16547043
The DtxR regulon of Corynebacterium glutamicum.
Wennerhold J, Bott M., J Bacteriol 188(8), 2006
PMID: 16585752
Transcription of the contiguous sigB, dtxR, and galE genes in Corynebacterium diphtheriae: evidence for multiple transcripts and regulation by environmental factors.
Oram DM, Jacobson AD, Holmes RK., J Bacteriol 188(8), 2006
PMID: 16585757
Engineering of a xylose metabolic pathway in Corynebacterium glutamicum.
Kawaguchi H, Vertès AA, Okino S, Inui M, Yukawa H., Appl Environ Microbiol 72(5), 2006
PMID: 16672486
High-throughput transposon mutagenesis of Corynebacterium glutamicum and construction of a single-gene disruptant mutant library.
Suzuki N, Okai N, Nonaka H, Tsuge Y, Inui M, Yukawa H., Appl Environ Microbiol 72(5), 2006
PMID: 16672528
Signature proteins that are distinctive characteristics of Actinobacteria and their subgroups.
Gao B, Paramanathan R, Gupta RS., Antonie Van Leeuwenhoek 90(1), 2006
PMID: 16670965
Application of global analysis techniques to Corynebacterium glutamicum: new insights into nitrogen regulation.
Silberbach M, Burkovski A., J Biotechnol 126(1), 2006
PMID: 16698104
Analysis and modeling of mycolyl-transferases in the CMN group.
Ramulu HG, Adindla S, Guruprasad L., Bioinformation 1(5), 2006
PMID: 17597881
Theoretical analysis of amino acid-producing Escherichia coli using a stoichiometric model and multivariate linear regression.
Van Dien SJ, Iwatani S, Usuda Y, Matsui K., J Biosci Bioeng 102(1), 2006
PMID: 16952834
Random mutagenesis in Corynebacterium glutamicum ATCC 13032 using an IS6100-based transposon vector identified the last unknown gene in the histidine biosynthesis pathway.
Mormann S, Lömker A, Rückert C, Gaigalat L, Tauch A, Pühler A, Kalinowski J., BMC Genomics 7(), 2006
PMID: 16901339
Siderophore-mediated iron transport in Bacillus subtilis and Corynebacterium glutamicum.
Dertz EA, Stintzi A, Raymond KN., J Biol Inorg Chem 11(8), 2006
PMID: 16912897
Production system for biodegradable polyester polyhydroxybutyrate by Corynebacterium glutamicum.
Jo SJ, Maeda M, Ooi T, Taguchi S., J Biosci Bioeng 102(3), 2006
PMID: 17046539
Global gene expression during stringent response in Corynebacterium glutamicum in presence and absence of the rel gene encoding (p)ppGpp synthase.
Brockmann-Gretza O, Kalinowski J., BMC Genomics 7(), 2006
PMID: 16961923
Functional analysis of the twin-arginine translocation pathway in Corynebacterium glutamicum ATCC 13869.
Kikuchi Y, Date M, Itaya H, Matsui K, Wu LF., Appl Environ Microbiol 72(11), 2006
PMID: 16997984
Evolution and expansion of the Mycobacterium tuberculosis PE and PPE multigene families and their association with the duplication of the ESAT-6 (esx) gene cluster regions.
Gey van Pittius NC, Sampson SL, Lee H, Kim Y, van Helden PD, Warren RM., BMC Evol Biol 6(), 2006
PMID: 17105670
Genome Properties: a system for the investigation of prokaryotic genetic content for microbiology, genome annotation and comparative genomics.
Haft DH, Selengut JD, Brinkac LM, Zafar N, White O., Bioinformatics 21(3), 2005
PMID: 15347579
Cre/loxP-mediated deletion system for large genome rearrangements in Corynebacterium glutamicum.
Suzuki N, Tsuge Y, Inui M, Yukawa H., Appl Microbiol Biotechnol 67(2), 2005
PMID: 15834716
The PEP-pyruvate-oxaloacetate node as the switch point for carbon flux distribution in bacteria.
Sauer U, Eikmanns BJ., FEMS Microbiol Rev 29(4), 2005
PMID: 16102602
Methionine production by fermentation.
Kumar D, Gomes J., Biotechnol Adv 23(1), 2005
PMID: 15610965
Molecular characterization of resistance-nodulation-division transporters from solvent- and drug-resistant bacteria in petroleum-contaminated soil.
Meguro N, Kodama Y, Gallegos MT, Watanabe K., Appl Environ Microbiol 71(1), 2005
PMID: 15640241
Prediction of functional class of novel bacterial proteins without the use of sequence similarity by a statistical learning method.
Cui J, Han LY, Cai CZ, Zheng CJ, Ji ZL, Chen YZ., J Mol Microbiol Biotechnol 9(2), 2005
PMID: 16319498
Pyruvate:quinone oxidoreductase from Corynebacterium glutamicum: purification and biochemical characterization.
Schreiner ME, Eikmanns BJ., J Bacteriol 187(3), 2005
PMID: 15659664
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The McbR repressor modulated by the effector substance S-adenosylhomocysteine controls directly the transcription of a regulon involved in sulphur metabolism of Corynebacterium glutamicum ATCC 13032.
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Purification and characterization of succinate:menaquinone oxidoreductase from Corynebacterium glutamicum.
Kurokawa T, Sakamoto J., Arch Microbiol 183(5), 2005
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Large-scale engineering of the Corynebacterium glutamicum genome.
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Phosphate starvation-inducible gene ushA encodes a 5' nucleotidase required for growth of Corynebacterium glutamicum on media with nucleotides as the phosphorus source.
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The whcE gene of Corynebacterium glutamicum is important for survival following heat and oxidative stress.
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Identification of a promoter motif regulating the major DNA damage response mechanism of Mycobacterium tuberculosis.
Gamulin V, Cetkovic H, Ahel I., FEMS Microbiol Lett 238(1), 2004
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Roles of pyruvate kinase and malic enzyme in Corynebacterium glutamicum for growth on carbon sources requiring gluconeogenesis.
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Using functional genomics to improve productivity in the manufacture of industrial biochemicals.
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Deletion of the genes encoding the MtrA-MtrB two-component system of Corynebacterium glutamicum has a strong influence on cell morphology, antibiotics susceptibility and expression of genes involved in osmoprotection.
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Molecular identification of the urea uptake system and transcriptional analysis of urea transporter- and urease-encoding genes in Corynebacterium glutamicum.
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The complete genome sequence and analysis of Corynebacterium diphtheriae NCTC13129.
Cerdeño-Tárraga AM, Efstratiou A, Dover LG, Holden MT, Pallen M, Bentley SD, Besra GS, Churcher C, James KD, De Zoysa A, Chillingworth T, Cronin A, Dowd L, Feltwell T, Hamlin N, Holroyd S, Jagels K, Moule S, Quail MA, Rabbinowitsch E, Rutherford KM, Thomson NR, Unwin L, Whitehead S, Barrell BG, Parkhill J., Nucleic Acids Res 31(22), 2003
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Development of a Corynebacterium glutamicum DNA microarray and validation by genome-wide expression profiling during growth with propionate as carbon source.
Hüser AT, Becker A, Brune I, Dondrup M, Kalinowski J, Plassmeier J, Pühler A, Wiegräbe I, Tauch A., J Biotechnol 106(2-3), 2003
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