Sequence of the 68,869 bp IncP-1 alpha plasmid pTB11 from a waste-water treatment plant reveals a highly conserved backbone, a Tn402-like integron and other transposable elements

Tennstedt T, Szczepanowski R, Krahn I, Pühler A, Schlüter A (2005)
PLASMID 53(3): 218-238.

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DOI
Autor*in
Tennstedt, T.; Szczepanowski, RafaelUniBi; Krahn, IreneUniBi; Pühler, AlfredUniBi ; Schlüter, AndreasUniBi
Einrichtung
Centrum für Biotechnologie > Institut für Genomforschung und Systembiologie
Fakultät für Biologie > Genetik der Prokaryoten
Centrum für Biotechnologie > Arbeitsgruppe A. Pühler
Abstract / Bemerkung
To analyse the significance of conjugative broad-host-range IncP-lot plasmids for the spread of antibiotic resistance determinants in waste-water treatment plants we isolated and characterised five different IncP-lot plasmids from bacteria of activated sludge and the final effluents of a municipal waste-water treatment plant. These plasmids mediate resistance to ampicillin, cefaclor, cefuroxime, gentamicin, kanamycin, spectinomycin, streptomycin, tetracycline, tobramycin, and trimethoprim. The complete 68,869 bp DNA-sequence of the IncP-1α plasmid pTB11 was determined. The pTB11 backbone modules for replication (Rep), mating pair formation (Trb), multimer resolution (Mrs), post-segregational killing (Psk), conjugative DNA-transfer (Tra), plasmid control (01), and stable maintenance and inheritance (KilA, KilE, and KilC) are highly conserved as compared to the ′ Birmingham′ IncP-lα plasmids. In contrast to the ′ Birmingham′ plasmids pTB11 carries an insert of a Tn402-derivative integrating a class 1 integron in the intergenic region between the multimer resolution operon parCBA and the post-segregational killing operon parDE. The integron comprises the resistance gene cassettes oxa2 (β-lactamase), aacA4 (aminoglycoside-6′ N-acetyltransferase), and aadA1 (aminoglycoside-3′-adenylyltransfetase) and a complete tniABQR transposition module. Integron-specific sequences were also identified on other IncP-lα plasmids analysed in this work. In contrast to the ′ Birmingham′ plasmids the pTB11 tetracycline resistance module carries a pecM- and a pncA-like gene downstream of the tetracycline resistance gene tetA and contains an insertion of the new insertion sequence element ISTB11. The transposable elements IS21 and Tn1 which disrupted, respectively, orf7 and klcB on the ′ Birmingham′ plasmids are not present on pTB11. Identification of IncP-lα plasmids in bacteria of the waste-water treatment plant's final effluents indicates that bacteria carrying these kind of plasmids are released into the environment. © 2004 Elsevier Inc. All rights reserved.
Stichworte
broad-host-range plasmid; multiresistance plasmid; integron; transposable element; activated sludge; conjugative plasmid
Erscheinungsjahr
2005
Zeitschriftentitel
PLASMID
Band
53
Ausgabe
3
Seite(n)
218-238
ISSN
0147-619X
Page URI
https://pub.uni-bielefeld.de/record/1603956

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Tennstedt T, Szczepanowski R, Krahn I, Pühler A, Schlüter A. Sequence of the 68,869 bp IncP-1 alpha plasmid pTB11 from a waste-water treatment plant reveals a highly conserved backbone, a Tn402-like integron and other transposable elements. PLASMID. 2005;53(3):218-238.
Tennstedt, T., Szczepanowski, R., Krahn, I., Pühler, A., & Schlüter, A. (2005). Sequence of the 68,869 bp IncP-1 alpha plasmid pTB11 from a waste-water treatment plant reveals a highly conserved backbone, a Tn402-like integron and other transposable elements. PLASMID, 53(3), 218-238. https://doi.org/10.1016/j.plasmid.2004.09.004
Tennstedt, T., Szczepanowski, Rafael, Krahn, Irene, Pühler, Alfred, and Schlüter, Andreas. 2005. “Sequence of the 68,869 bp IncP-1 alpha plasmid pTB11 from a waste-water treatment plant reveals a highly conserved backbone, a Tn402-like integron and other transposable elements”. PLASMID 53 (3): 218-238.
Tennstedt, T., Szczepanowski, R., Krahn, I., Pühler, A., and Schlüter, A. (2005). Sequence of the 68,869 bp IncP-1 alpha plasmid pTB11 from a waste-water treatment plant reveals a highly conserved backbone, a Tn402-like integron and other transposable elements. PLASMID 53, 218-238.
Tennstedt, T., et al., 2005. Sequence of the 68,869 bp IncP-1 alpha plasmid pTB11 from a waste-water treatment plant reveals a highly conserved backbone, a Tn402-like integron and other transposable elements. PLASMID, 53(3), p 218-238.
T. Tennstedt, et al., “Sequence of the 68,869 bp IncP-1 alpha plasmid pTB11 from a waste-water treatment plant reveals a highly conserved backbone, a Tn402-like integron and other transposable elements”, PLASMID, vol. 53, 2005, pp. 218-238.
Tennstedt, T., Szczepanowski, R., Krahn, I., Pühler, A., Schlüter, A.: Sequence of the 68,869 bp IncP-1 alpha plasmid pTB11 from a waste-water treatment plant reveals a highly conserved backbone, a Tn402-like integron and other transposable elements. PLASMID. 53, 218-238 (2005).
Tennstedt, T., Szczepanowski, Rafael, Krahn, Irene, Pühler, Alfred, and Schlüter, Andreas. “Sequence of the 68,869 bp IncP-1 alpha plasmid pTB11 from a waste-water treatment plant reveals a highly conserved backbone, a Tn402-like integron and other transposable elements”. PLASMID 53.3 (2005): 218-238.

53 Zitationen in Europe PMC

Daten bereitgestellt von Europe PubMed Central.

UPLC-MS/MS analysis of antibiotics in pharmaceutical effluent in Tunisia: ecotoxicological impact and multi-resistant bacteria dissemination.
Tahrani L, Mehri I, Reyns T, Anthonissen R, Verschaeve L, Khalifa ABH, Loco JV, Abdenaceur H, Mansour HB., Arch Microbiol 200(4), 2018
PMID: 29230492
Research progress on distribution, migration, transformation of antibiotics and antibiotic resistance genes (ARGs) in aquatic environment.
Shao S, Hu Y, Cheng J, Chen Y., Crit Rev Biotechnol 38(8), 2018
PMID: 29807455
Analysis of Virulence Factors and Antimicrobial Resistance in Salmonella Using Molecular Techniques and Identification of Clonal Relationships Among the Strains.
Unlu O, Aktas Z, Tugrul HM., Microb Drug Resist (), 2018
PMID: 29920160
Solar photocatalysis as disinfection technique: Inactivation of Klebsiella pneumoniae in sewage and investigation of changes in antibiotic resistance profile.
Venieri D, Gounaki I, Bikouvaraki M, Binas V, Zachopoulos A, Kiriakidis G, Mantzavinos D., J Environ Manage 195(pt 2), 2017
PMID: 27316624
Adaptation of genetically monomorphic bacteria: evolution of copper resistance through multiple horizontal gene transfers of complex and versatile mobile genetic elements.
Richard D, Ravigné V, Rieux A, Facon B, Boyer C, Boyer K, Grygiel P, Javegny S, Terville M, Canteros BI, Robène I, Vernière C, Chabirand A, Pruvost O, Lefeuvre P., Mol Ecol 26(7), 2017
PMID: 28101896
Diversification of broad host range plasmids correlates with the presence of antibiotic resistance genes.
Li X, Wang Y, Brown CJ, Yao F, Jiang Y, Top EM, Li H., FEMS Microbiol Ecol 92(1), 2016
PMID: 26635412
Novel Aminoglycoside Resistance Transposons and Transposon-Derived Circular Forms Detected in Carbapenem-Resistant Acinetobacter baumannii Clinical Isolates.
Karah N, Dwibedi CK, Sjöström K, Edquist P, Johansson A, Wai SN, Uhlin BE., Antimicrob Agents Chemother 60(3), 2016
PMID: 26824943
Co-occurrence of integrase 1, antibiotic and heavy metal resistance genes in municipal wastewater treatment plants.
Di Cesare A, Eckert EM, D'Urso S, Bertoni R, Gillan DC, Wattiez R, Corno G., Water Res 94(), 2016
PMID: 26945964
Genomics of high molecular weight plasmids isolated from an on-farm biopurification system.
Martini MC, Wibberg D, Lozano M, Torres Tejerizo G, Albicoro FJ, Jaenicke S, van Elsas JD, Petroni A, Garcillán-Barcia MP, de la Cruz F, Schlüter A, Pühler A, Pistorio M, Lagares A, Del Papa MF., Sci Rep 6(), 2016
PMID: 27321040
Conjugative multiple-antibiotic resistance plasmids in Escherichia coli isolated from environmental waters contaminated by human faecal wastes.
Laroche-Ajzenberg E, Flores Ribeiro A, Bodilis J, Riah W, Buquet S, Chaftar N, Pawlak B., J Appl Microbiol 118(2), 2015
PMID: 25387599
Antimicrobial resistance determinants of Escherichia coli isolates recovered from some rivers in Osun State, South-Western Nigeria: Implications for public health.
Titilawo Y, Obi L, Okoh A., Sci Total Environ 523(), 2015
PMID: 25862994
Genomic interplay in bacterial communities: implications for growth promoting practices in animal husbandry.
Roy Chowdhury P, McKinnon J, Wyrsch E, Hammond JM, Charles IG, Djordjevic SP., Front Microbiol 5(), 2014
PMID: 25161648
The role of the natural environment in the emergence of antibiotic resistance in gram-negative bacteria.
Wellington EM, Boxall AB, Cross P, Feil EJ, Gaze WH, Hawkey PM, Johnson-Rollings AS, Jones DL, Lee NM, Otten W, Thomas CM, Williams AP., Lancet Infect Dis 13(2), 2013
PMID: 23347633
High-level aminoglycoside resistance and virulence characteristics among Enterococci isolated from recreational beaches in Malaysia.
Dada AC, Ahmad A, Usup G, Heng LY, Hamid R., Environ Monit Assess 185(9), 2013
PMID: 23417753
Broad-host-range IncP-1 plasmids and their resistance potential.
Popowska M, Krawczyk-Balska A., Front Microbiol 4(), 2013
PMID: 23471189
Environmental and Public Health Implications of Water Reuse: Antibiotics, Antibiotic Resistant Bacteria, and Antibiotic Resistance Genes.
Hong PY, Al-Jassim N, Ansari MI, Mackie RI., Antibiotics (Basel) 2(3), 2013
PMID: 27029309
Metagenomic profiling of antibiotic resistance genes and mobile genetic elements in a tannery wastewater treatment plant.
Wang Z, Zhang XX, Huang K, Miao Y, Shi P, Liu B, Long C, Li A., PLoS One 8(10), 2013
PMID: 24098424
Nanoalumina promotes the horizontal transfer of multiresistance genes mediated by plasmids across genera.
Qiu Z, Yu Y, Chen Z, Jin M, Yang D, Zhao Z, Wang J, Shen Z, Wang X, Qian D, Huang A, Zhang B, Li JW., Proc Natl Acad Sci U S A 109(13), 2012
PMID: 22411796
Phylogeny of replication initiator protein TrfA reveals a highly divergent clade of incompatibility group P1 plasmids.
Stenger DC, Lee MW., Appl Environ Microbiol 77(7), 2011
PMID: 21296948
The IncP-1 plasmid backbone adapts to different host bacterial species and evolves through homologous recombination.
Norberg P, Bergström M, Jethava V, Dubhashi D, Hermansson M., Nat Commun 2(), 2011
PMID: 21468020
Evolution of IncP-1α plasmids by acquisition of antibiotic and mercuric ion resistance transposons.
Pinyon JL, Hall RM., Microb Drug Resist 17(3), 2011
PMID: 21476866
Exploration of horizontal gene transfer between transplastomic tobacco and plant-associated bacteria.
Demanèche S, Monier JM, Dugat-Bony E, Simonet P., FEMS Microbiol Ecol 78(1), 2011
PMID: 21564143
Plasmid metagenome reveals high levels of antibiotic resistance genes and mobile genetic elements in activated sludge.
Zhang T, Zhang XX, Ye L., PLoS One 6(10), 2011
PMID: 22016806
Dispersal of carbapenemase blaVIM-1 gene associated with different Tn402 variants, mercury transposons, and conjugative plasmids in Enterobacteriaceae and Pseudomonas aeruginosa.
Tato M, Coque TM, Baquero F, Cantón R., Antimicrob Agents Chemother 54(1), 2010
PMID: 19901094
Tn502 and Tn512 are res site hunters that provide evidence of resolvase-independent transposition to random sites.
Petrovski S, Stanisich VA., J Bacteriol 192(7), 2010
PMID: 20118251
Relative strengths of the class 1 integron promoter hybrid 2 and the combinations of strong and hybrid 1 with an active p2 promoter.
Papagiannitsis CC, Tzouvelekis LS, Miriagou V., Antimicrob Agents Chemother 53(1), 2009
PMID: 19001114
Antibiotic resistance genes in water environment.
Zhang XX, Zhang T, Fang HH., Appl Microbiol Biotechnol 82(3), 2009
PMID: 19130050
Characterization and quantification of class 1 integrons and associated gene cassettes in sewage treatment plants.
Zhang XX, Zhang T, Zhang M, Fang HH, Cheng SP., Appl Microbiol Biotechnol 82(6), 2009
PMID: 19224208
All IncP-1 plasmid subgroups, including the novel epsilon subgroup, are prevalent in the influent of a Danish wastewater treatment plant.
Bahl MI, Burmølle M, Meisner A, Hansen LH, Sørensen SJ., Plasmid 62(2), 2009
PMID: 19501117
Novel organization of aromatic degradation pathway genes in a microbial community as revealed by metagenomic analysis.
Suenaga H, Koyama Y, Miyakoshi M, Miyazaki R, Yano H, Sota M, Ohtsubo Y, Tsuda M, Miyazaki K., ISME J 3(12), 2009
PMID: 19587775
Influence of industrial contamination on mobile genetic elements: class 1 integron abundance and gene cassette structure in aquatic bacterial communities.
Wright MS, Baker-Austin C, Lindell AH, Stepanauskas R, Stokes HW, McArthur JV., ISME J 2(4), 2008
PMID: 18273063
Genetic diversity and composition of a plasmid metagenome from a wastewater treatment plant.
Schlüter A, Krause L, Szczepanowski R, Goesmann A, Pühler A., J Biotechnol 136(1-2), 2008
PMID: 18603322
A class 1 integron present in a human commensal has a hybrid transposition module compared to Tn402: evidence of interaction with mobile DNA from natural environments.
Labbate M, Roy Chowdhury P, Stokes HW., J Bacteriol 190(15), 2008
PMID: 18502858
Insight into the plasmid metagenome of wastewater treatment plant bacteria showing reduced susceptibility to antimicrobial drugs analysed by the 454-pyrosequencing technology.
Szczepanowski R, Bekel T, Goesmann A, Krause L, Krömeke H, Kaiser O, Eichler W, Pühler A, Schlüter A., J Biotechnol 136(1-2), 2008
PMID: 18586057
Novel macrolide resistance module carried by the IncP-1beta resistance plasmid pRSB111, isolated from a wastewater treatment plant.
Szczepanowski R, Krahn I, Bohn N, Pühler A, Schlüter A., Antimicrob Agents Chemother 51(2), 2007
PMID: 17101677
Erythromycin resistance-conferring plasmid pRSB105, isolated from a sewage treatment plant, harbors a new macrolide resistance determinant, an integron-containing Tn402-like element, and a large region of unknown function.
Schlüter A, Szczepanowski R, Kurz N, Schneiker S, Krahn I, Pühler A., Appl Environ Microbiol 73(6), 2007
PMID: 17261525
Antimicrobial resistance patterns in Enterobacteriaceae isolated from an urban wastewater treatment plant.
Ferreira da Silva M, Vaz-Moreira I, Gonzalez-Pajuelo M, Nunes OC, Manaia CM., FEMS Microbiol Ecol 60(1), 2007
PMID: 17250754
Region-specific insertion of transposons in combination with selection for high plasmid transferability and stability accounts for the structural similarity of IncP-1 plasmids.
Sota M, Tsuda M, Yano H, Suzuki H, Forney LJ, Top EM., J Bacteriol 189(8), 2007
PMID: 17277066
Plasmid replicon typing of commensal and pathogenic Escherichia coli isolates.
Johnson TJ, Wannemuehler YM, Johnson SJ, Logue CM, White DG, Doetkott C, Nolan LK., Appl Environ Microbiol 73(6), 2007
PMID: 17277222
The multiple antibiotic resistance IncP-1 plasmid pKJK5 isolated from a soil environment is phylogenetically divergent from members of the previously established alpha, beta and delta sub-groups.
Bahl MI, Hansen LH, Goesmann A, Sørensen SJ., Plasmid 58(1), 2007
PMID: 17306874
Sequence of plasmid pBS228 and reconstruction of the IncP-1alpha phylogeny.
Haines AS, Jones K, Batt SM, Kosheleva IA, Thomas CM., Plasmid 58(1), 2007
PMID: 17320955
Genomics of IncP-1 antibiotic resistance plasmids isolated from wastewater treatment plants provides evidence for a widely accessible drug resistance gene pool.
Schlüter A, Szczepanowski R, Pühler A, Top EM., FEMS Microbiol Rev 31(4), 2007
PMID: 17553065
Detection of gene cassettes in Tn402-like class 1 integrons.
Post V, Recchia GD, Hall RM., Antimicrob Agents Chemother 51(9), 2007
PMID: 17591852
IncP-1-beta plasmid pGNB1 isolated from a bacterial community from a wastewater treatment plant mediates decolorization of triphenylmethane dyes.
Schlüter A, Krahn I, Kollin F, Bönemann G, Stiens M, Szczepanowski R, Schneiker S, Pühler A., Appl Environ Microbiol 73(20), 2007
PMID: 17675426
Sequence and analysis of the 46.6-kb plasmid pA1 from Sphingomonas sp. A1 that corresponds to the typical IncP-1beta plasmid backbone without any accessory gene.
Harada KM, Aso Y, Hashimoto W, Mikami B, Murata K., Plasmid 56(1), 2006
PMID: 16445980
Co-selection of antibiotic and metal resistance.
Baker-Austin C, Wright MS, Stepanauskas R, McArthur JV., Trends Microbiol 14(4), 2006
PMID: 16537105
Characterization of the replication, maintenance, and transfer features of the IncP-7 plasmid pCAR1, which carries genes involved in carbazole and dioxin degradation.
Shintani M, Yano H, Habe H, Omori T, Yamane H, Tsuda M, Nojiri H., Appl Environ Microbiol 72(5), 2006
PMID: 16672459
Sequence analysis of the 144-kilobase accessory plasmid pSmeSM11a, isolated from a dominant Sinorhizobium meliloti strain identified during a long-term field release experiment.
Stiens M, Schneiker S, Keller M, Kuhn S, Pühler A, Schlüter A., Appl Environ Microbiol 72(5), 2006
PMID: 16672515
Dissemination and persistence of blaCTX-M-9 are linked to class 1 integrons containing CR1 associated with defective transposon derivatives from Tn402 located in early antibiotic resistance plasmids of IncHI2, IncP1-alpha, and IncFI groups.
Novais A, Cantón R, Valverde A, Machado E, Galán JC, Peixe L, Carattoli A, Baquero F, Coque TM., Antimicrob Agents Chemother 50(8), 2006
PMID: 16870767
Class 1 integrons potentially predating the association with tn402-like transposition genes are present in a sediment microbial community.
Stokes HW, Nesbø CL, Holley M, Bahl MI, Gillings MR, Boucher Y., J Bacteriol 188(16), 2006
PMID: 16885440
The CTX-M beta-lactamase pandemic.
Cantón R, Coque TM., Curr Opin Microbiol 9(5), 2006
PMID: 16942899
Combinatorial genetic evolution of multiresistance.
Walsh TR., Curr Opin Microbiol 9(5), 2006
PMID: 16942901
Mobilizable IncQ-related plasmid carrying a new quinolone resistance gene, qnrS2, isolated from the bacterial community of a wastewater treatment plant.
Bönemann G, Stiens M, Pühler A, Schlüter A., Antimicrob Agents Chemother 50(9), 2006
PMID: 16940104

46 References

Daten bereitgestellt von Europe PubMed Central.

Spread and survival of promiscuous IncP-1 plasmids.
Adamczyk M, Jagura-Burdzy G., Acta Biochim. Pol. 50(2), 2003
PMID: 12833168
Complete nucleotide sequence of Tn1721: gene organization and a novel gene product with features of a chemotaxis protein.
Allmeier H, Cresnar B, Greck M, Schmitt R., Gene 111(1), 1992
PMID: 1312499
The integrons In0, In2, and In5 are defective transposon derivatives.
Brown HJ, Stokes HW, Hall RM., J. Bacteriol. 178(15), 1996
PMID: 8755869
Relationship of group P1 plasmids revealed by heteroduplex experiments: RP1, RP4, R68 and RK2 are identical.
Burkardt HJ, Riess G, Puhler A., J. Gen. Microbiol. 114(2), 1979
PMID: 120408
Properties of an R factor from Pseudomonas aeruginosa.
Datta N, Hedges RW, Shaw EJ, Sykes RB, Richmond MH., J. Bacteriol. 108(3), 1971
PMID: 4945193
Genetic exchange between bacteria in the environment.
Davison J., Plasmid 42(2), 1999
PMID: 10489325
Horizontal gene transfer as a biosafety issue: a natural phenomenon of public concern.
Droge M, Puhler A, Selbitschka W., J. Biotechnol. 64(1), 1998
PMID: 9823660
Phenotypic and molecular characterization of conjugative antibiotic resistance plasmids isolated from bacterial communities of activated sludge.
Droge M, Puhler A, Selbitschka W., Mol. Gen. Genet. 263(3), 2000
PMID: 10821181
Analysis of the multimer resolution system encoded by the parCBA operon of broad-host-range plasmid RP4.
Eberl L, Kristensen CS, Givskov M, Grohmann E, Gerlitz M, Schwab H., Mol. Microbiol. 12(1), 1994
PMID: 8057833
Detection and characterization of broad-host-range plasmids in environmental bacteria by PCR.
Gotz A, Pukall R, Smit E, Tietze E, Prager R, Tschape H, van Elsas JD, Smalla K., Appl. Environ. Microbiol. 62(7), 1996
PMID: 8779598
Differential plasmid rescue from transgenic mouse DNAs into Escherichia coli methylation-restriction mutants.
Grant SG, Jessee J, Bloom FR, Hanahan D., Proc. Natl. Acad. Sci. U.S.A. 87(12), 1990
PMID: 2162051
Integrons found in different locations have identical 5' ends but variable 3' ends.
Hall RM, Brown HJ, Brookes DE, Stokes HW., J. Bacteriol. 176(20), 1994
PMID: 7929000
Occurrence, fate and effects of pharmaceutical substances in the environment--a review.
Halling-Sorensen B, Nors Nielsen S, Lanzky PF, Ingerslev F, Holten Lutzhoft HC, Jorgensen SE., Chemosphere 36(2), 1998
PMID: 9569937
The development of plasmid-free strains of Agrobacterium tumefaciens by using incompatibility with a Rhizobium meliloti plasmid to eliminate pAtC58.
Hynes MF, Simon R, Puhler A., Plasmid 13(2), 1985
PMID: 4001194
Molecular characterization of the R factors implicated in the carbenicillin resistance of a sequence of Pseudomonas aeruginosa strains isolated from burns.
Ingram LC, Richmond MH, Sykes RB., Antimicrob. Agents Chemother. 3(2), 1973
PMID: 4208284
Transposon targeting determined by resolvase.
Kamali-Moghaddam M, Sundstrom L., FEMS Microbiol. Lett. 186(1), 2000
PMID: 10779712
REPuter: the manifold applications of repeat analysis on a genomic scale.
Kurtz S, Choudhuri JV, Ohlebusch E, Schleiermacher C, Stoye J, Giegerich R., Nucleic Acids Res. 29(22), 2001
PMID: 11713313
Gene islands integrated into tRNA(Gly) genes confer genome diversity on a Pseudomonas aeruginosa clone.
Larbig KD, Christmann A, Johann A, Klockgether J, Hartsch T, Merkl R, Wiehlmann L, Fritz HJ, Tummler B., J. Bacteriol. 184(23), 2002
PMID: 12426355
Cloning and characterization of blaVIM, a new integron-borne metallo-beta-lactamase gene from a Pseudomonas aeruginosa clinical isolate.
Lauretti L, Riccio ML, Mazzariol A, Cornaglia G, Amicosante G, Fontana R, Rossolini GM., Antimicrob. Agents Chemother. 43(7), 1999
PMID: 10390207
PCR mapping of integrons reveals several novel combinations of resistance genes.
Levesque C, Piche L, Larose C, Roy PH., Antimicrob. Agents Chemother. 39(1), 1995
PMID: 7695304
Molecular analysis of the replication elements of the broad-host-range RepA/C replicon.
Llanes C, Gabant P, Couturier M, Bayer L, Plesiat P., Plasmid 36(1), 1996
PMID: 8938049
Complete nucleotide sequence and organization of the atrazine catabolic plasmid pADP-1 from Pseudomonas sp. strain ADP.
Martinez B, Tomkins J, Wackett LP, Wing R, Sadowsky MJ., J. Bacteriol. 183(19), 2001
PMID: 11544232
Antibiotic resistance in microbes.
Mazel D, Davies J., Cell. Mol. Life Sci. 56(9-10), 1999
PMID: 11212334
GenDB--an open source genome annotation system for prokaryote genomes.
Meyer F, Goesmann A, McHardy AC, Bartels D, Bekel T, Clausen J, Kalinowski J, Linke B, Rupp O, Giegerich R, Puhler A., Nucleic Acids Res. 31(8), 2003
PMID: 12682369
Complete nucleotide sequence of Birmingham IncP alpha plasmids. Compilation and comparative analysis.
Pansegrau W, Lanka E, Barth PT, Figurski DH, Guiney DG, Haas D, Helinski DR, Schwab H, Stanisich VA, Thomas CM., J. Mol. Biol. 239(5), 1994
PMID: 8014987
Characterization and movement of the class 1 integron known as Tn2521 and Tn1405.
Partridge SR, Brown HJ, Hall RM., Antimicrob. Agents Chemother. 46(5), 2002
PMID: 11959558
Partial characterization of a transposon containing the tet(A) determinant in a clinical isolate of Acinetobacter baumannii.
Ribera A, Roca I, Ruiz J, Gibert I, Vila J., J. Antimicrob. Chemother. 52(3), 2003
PMID: 12888597
Primer3 on the WWW for general users and for biologist programmers
Rozen, 2000

Sambrook, 1989
The 64 508 bp IncP-1beta antibiotic multiresistance plasmid pB10 isolated from a waste-water treatment plant provides evidence for recombination between members of different branches of the IncP-1beta group.
Schluter A, Heuer H, Szczepanowski R, Forney LJ, Thomas CM, Puhler A, Top EM., Microbiology (Reading, Engl.) 149(Pt 11), 2003
PMID: 14600226
Occurrence and reservoirs of antibiotic resistance genes in the environment
Seveno, Rev. Med. Microbiol. 13(), 2002
A chromosomally located transposon in Pseudomonas aeruginosa
Sinclair, J. Bacteriol. 185(), 1982
Exogenous isolation of antibiotic resistance plasmids from piggery manure slurries reveals a high prevalence and diversity of IncQ-like plasmids.
Smalla K, Heuer H, Gotz A, Niemeyer D, Krogerrecklenfort E, Tietze E., Appl. Environ. Microbiol. 66(11), 2000
PMID: 11055935
Comparison of the nucleotide sequences of the vegetative replication origins of broad host range IncP plasmids R751 and RK2 reveals conserved features of probable functional importance.
Smith CA, Thomas CM., Nucleic Acids Res. 13(2), 1985
PMID: 4000925
Comparison of the organisation of the genomes of phenotypically diverse plasmids of incompatibility group P: members of the IncP beta sub-group are closely related.
Smith CA, Thomas CM., Mol. Gen. Genet. 206(3), 1987
PMID: 3035342
Integron-containing IncU R plasmids pRAS1 and pAr-32 from the fish pathogen Aeromonas salmonicida.
Sorum H, L'Abee-Lund TM, Solberg A, Wold A., Antimicrob. Agents Chemother. 47(4), 2003
PMID: 12654659
Structure of haloacetate-catabolic IncP-1beta plasmid pUO1 and genetic mobility of its residing haloacetate-catabolic transposon.
Sota M, Kawasaki H, Tsuda M., J. Bacteriol. 185(22), 2003
PMID: 14594853
The Staden sequence analysis package.
Staden R., Mol. Biotechnol. 5(3), 1996
PMID: 8837029
Complementation analysis in Pseudomonas aeruginosa of the transfer genes of the wide host range R plasmid R18.
Stokes HW, Moore RJ, Krishnapillai V., Plasmid 5(2), 1981
PMID: 6264523
The 79,370-bp conjugative plasmid pB4 consists of an IncP-1beta backbone loaded with a chromate resistance transposon, the strA-strB streptomycin resistance gene pair, the oxacillinase gene bla(NPS-1), and a tripartite antibiotic efflux system of the resistance-nodulation-division family.
Tauch A, Schluter A, Bischoff N, Goesmann A, Meyer F, Puhler A., Mol. Genet. Genomics 268(5), 2003
PMID: 12589432
Occurrence of integron-associated resistance gene cassettes located on antibiotic resistance plasmids isolated from a wastewater treatment plant.
Tennstedt T, Szczepanowski R, Braun S, Puhler A, Schluter A., FEMS Microbiol. Ecol. 45(3), 2003
PMID: 19719593
Incompatibility group P plasmids: genetics, evolution, and use in genetic manipulation.
Thomas CM, Smith CA., Annu. Rev. Microbiol. 41(), 1987
PMID: 3318684
Paradigms of plasmid organization.
Thomas CM., Mol. Microbiol. 37(3), 2000
PMID: 10931342
Complete sequence of the IncPbeta plasmid R751: implications for evolution and organisation of the IncP backbone.
Thorsted PB, Macartney DP, Akhtar P, Haines AS, Ali N, Davidson P, Stafford T, Pocklington MJ, Pansegrau W, Wilkins BM, Lanka E, Thomas CM., J. Mol. Biol. 282(5), 1998
PMID: 9753548
Map of the IncP1beta plasmid pTSA encoding the widespread genes (tsa) for p-toluenesulfonate degradation in Comamonas testosteroni T-2.
Tralau T, Cook AM, Ruff J., Appl. Environ. Microbiol. 67(4), 2001
PMID: 11282598
Genetic organization of the catabolic plasmid pJP4 from Ralstonia eutropha JMP134 (pJP4) reveals mechanisms of adaptation to chloroaromatic pollutants and evolution of specialized chloroaromatic degradation pathways.
Trefault N, De la Iglesia R, Molina AM, Manzano M, Ledger T, Perez-Pantoja D, Sanchez MA, Stuardo M, Gonzalez B., Environ. Microbiol. 6(7), 2004
PMID: 15186344
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