Ion Torrent PGM sequencing for genomic typing of Neisseria meningitidis for rapid determination of multiple layers of typing information

Vogel U, Szczepanowski R, Claus H, Jünemann S, Prior K, Harmsen D (2012)
Journal of clinical microbiology 50(6): 1889-1894.

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DOI
Autor*in
Vogel, Ulrich; Szczepanowski, RafaelUniBi; Claus, Heike; Jünemann, SebastianUniBi; Prior, Karola; Harmsen, Dag
Einrichtung
Centrum für Biotechnologie
Technische Fakultät > Computational Genomics
Technische Fakultät > AG Genominformatik
Abstract / Bemerkung
Neisseria meningitidis causes invasive meningococcal disease in infants, toddlers and adolescents worldwide. DNA sequence based typing has become the standard for molecular epidemiology of the organism including multilocus sequence typing, analysis of genetic determinants of antibiotic resistance, and sequence typing of vaccine antigens. However, PCR of multiple targets and consecutive Sanger sequencing provides logistic constraints to reference laboratories. Taking advantage of the recent development of benchtop next generation sequencers (NGS) and of BIGSdb, a database accommodating and analyzing genome sequence data, we therefore explored the feasibility and accuracy of Ion Torrent Personal Genome Machine™ (PGM™) sequencing for genomic typing of meningococci. Three strains from a previous meningococcus B community outbreak were selected to compare conventional typing results with data generated by semiconductor chip based sequencing. In addition, sequencing of the meningococcal type strain MC58 provided information about the general performance of the technology. The PGM™ technology generated sequence information for almost all target genes addressed. The results were 100% concordant with conventional typing results with no further editing necessary. In addition, the amount of typing information, i.e. nucleotides and target genes analyzed, could be substantially increased by the combined use of genome sequencing and BIGSdb compared to conventional methods. In a near future, affordable and fast benchtop-NGS machines like the PGM™ might enable reference laboratories to switch to genomic typing on a routine basis. This will reduce workload and rapidly provide information for laboratory surveillance, outbreak investigation, assessment of vaccine preventability and antibiotic resistance gene monitoring.
Erscheinungsjahr
2012
Zeitschriftentitel
Journal of clinical microbiology
Band
50
Ausgabe
6
Seite(n)
1889-1894
ISSN
0095-1137
Page URI
https://pub.uni-bielefeld.de/record/2490286

Zitieren

Vogel U, Szczepanowski R, Claus H, Jünemann S, Prior K, Harmsen D. Ion Torrent PGM sequencing for genomic typing of Neisseria meningitidis for rapid determination of multiple layers of typing information. Journal of clinical microbiology. 2012;50(6):1889-1894.
Vogel, U., Szczepanowski, R., Claus, H., Jünemann, S., Prior, K., & Harmsen, D. (2012). Ion Torrent PGM sequencing for genomic typing of Neisseria meningitidis for rapid determination of multiple layers of typing information. Journal of clinical microbiology, 50(6), 1889-1894. doi:10.1128/JCM.00038-12
Vogel, Ulrich, Szczepanowski, Rafael, Claus, Heike, Jünemann, Sebastian, Prior, Karola, and Harmsen, Dag. 2012. “Ion Torrent PGM sequencing for genomic typing of Neisseria meningitidis for rapid determination of multiple layers of typing information”. Journal of clinical microbiology 50 (6): 1889-1894.
Vogel, U., Szczepanowski, R., Claus, H., Jünemann, S., Prior, K., and Harmsen, D. (2012). Ion Torrent PGM sequencing for genomic typing of Neisseria meningitidis for rapid determination of multiple layers of typing information. Journal of clinical microbiology 50, 1889-1894.
Vogel, U., et al., 2012. Ion Torrent PGM sequencing for genomic typing of Neisseria meningitidis for rapid determination of multiple layers of typing information. Journal of clinical microbiology, 50(6), p 1889-1894.
U. Vogel, et al., “Ion Torrent PGM sequencing for genomic typing of Neisseria meningitidis for rapid determination of multiple layers of typing information”, Journal of clinical microbiology, vol. 50, 2012, pp. 1889-1894.
Vogel, U., Szczepanowski, R., Claus, H., Jünemann, S., Prior, K., Harmsen, D.: Ion Torrent PGM sequencing for genomic typing of Neisseria meningitidis for rapid determination of multiple layers of typing information. Journal of clinical microbiology. 50, 1889-1894 (2012).
Vogel, Ulrich, Szczepanowski, Rafael, Claus, Heike, Jünemann, Sebastian, Prior, Karola, and Harmsen, Dag. “Ion Torrent PGM sequencing for genomic typing of Neisseria meningitidis for rapid determination of multiple layers of typing information”. Journal of clinical microbiology 50.6 (2012): 1889-1894.

39 Zitationen in Europe PMC

Daten bereitgestellt von Europe PubMed Central.

Pseudomonas aeruginosa intensive care unit outbreak: winnowing of transmissions with molecular and genomic typing.
Parcell BJ, Oravcova K, Pinheiro M, Holden MTG, Phillips G, Turton JF, Gillespie SH., J Hosp Infect 98(3), 2018
PMID: 29229490
Identification of tick-borne pathogen diversity by metagenomic analysis in Haemaphysalis longicornis from Xinyang, China.
Zhuang L, Du J, Cui XM, Li H, Tang F, Zhang PH, Hu JG, Tong YG, Feng ZC, Liu W., Infect Dis Poverty 7(1), 2018
PMID: 29730989
Reference Grade Characterization of Polymorphisms in Full-Length HLA Class I and II Genes With Short-Read Sequencing on the ION PGM System and Long-Reads Generated by Single Molecule, Real-Time Sequencing on the PacBio Platform.
Suzuki S, Ranade S, Osaki K, Ito S, Shigenari A, Ohnuki Y, Oka A, Masuya A, Harting J, Baybayan P, Kitazume M, Sunaga J, Morishima S, Morishima Y, Inoko H, Kulski JK, Shiina T., Front Immunol 9(), 2018
PMID: 30337930
Retreatment efficacy and predictors of ledipasvir plus sofosbuvir to HCV genotype 1 in Japan.
Akuta N, Sezaki H, Suzuki F, Fujiyama S, Kawamura Y, Hosaka T, Kobayashi M, Kobayashi M, Saitoh S, Suzuki Y, Arase Y, Ikeda K, Kumada H., J Med Virol 89(2), 2017
PMID: 27357737
Evolutionary Events Associated with an Outbreak of Meningococcal Disease in Men Who Have Sex with Men.
Taha MK, Claus H, Lappann M, Veyrier FJ, Otto A, Becher D, Deghmane AE, Frosch M, Hellenbrand W, Hong E, Parent du Châtelet I, Prior K, Harmsen D, Vogel U., PLoS One 11(5), 2016
PMID: 27167067
BRCA1-2 diagnostic workflow from next-generation sequencing technologies to variant identification and final report.
Pilato B, Pinto R, De Summa S, Petriella D, Lacalamita R, Danza K, Paradiso A, Tommasi S., Genes Chromosomes Cancer 55(10), 2016
PMID: 27225819
Protease Inhibitor Resistance Remains Even After Mutant Strains Become Undetectable by Deep Sequencing.
Kan H, Imamura M, Uchida T, Hiraga N, Hayes CN, Tsuge M, Abe H, Aikata H, Makokha GN, Chowdhury S, Miki D, Ochi H, Ishida Y, Tateno C, Chayama K., J Infect Dis 214(11), 2016
PMID: 27651415
Technical Evaluation: Identification of Pathogenic Mutations in PKD1 and PKD2 in Patients with Autosomal Dominant Polycystic Kidney Disease by Next-Generation Sequencing and Use of a Comprehensive New Classification System.
Kinoshita M, Higashihara E, Kawano H, Higashiyama R, Koga D, Fukui T, Gondo N, Oka T, Kawahara K, Rigo K, Hague T, Katsuragi K, Sudo K, Takeshi M, Horie S, Nutahara K., PLoS One 11(11), 2016
PMID: 27835667
Semiconductor-based sequencing of genome-wide DNA methylation states.
Corley MJ, Zhang W, Zheng X, Lum-Jones A, Maunakea AK., Epigenetics 10(2), 2015
PMID: 25602802
Evolution and single-nucleotide polymorphisms in methicillin-resistant Staphylococcus aureus strains with reduced susceptibility to vancomycin and daptomycin, based on determination of the complete genome.
Yamaguchi T, Suzuki S, Okamura S, Miura Y, Tsukimori A, Nakamura I, Ito N, Masuya A, Shiina T, Matsumoto T., Antimicrob Agents Chemother 59(6), 2015
PMID: 25779584
Evolution of simeprevir-resistant variants in virological non-responders infected with HCV genotype 1b.
Akuta N, Suzuki F, Sezaki H, Hosaka T, Kobayashi M, Suzuki Y, Saitoh S, Kobayashi M, Ikeda K, Kumada H., J Med Virol 87(4), 2015
PMID: 25655809
Cost-efficient multiplex PCR for routine genotyping of up to nine classical HLA loci in a single analytical run of multiple samples by next generation sequencing.
Ozaki Y, Suzuki S, Kashiwase K, Shigenari A, Okudaira Y, Ito S, Masuya A, Azuma F, Yabe T, Morishima S, Mitsunaga S, Satake M, Ota M, Morishima Y, Kulski JK, Saito K, Inoko H, Shiina T., BMC Genomics 16(), 2015
PMID: 25895492
It Is Not All about Single Nucleotide Polymorphisms: Comparison of Mobile Genetic Elements and Deletions in Listeria monocytogenes Genomes Links Cases of Hospital-Acquired Listeriosis to the Environmental Source.
Wang Q, Holmes N, Martinez E, Howard P, Hill-Cawthorne G, Sintchenko V., J Clin Microbiol 53(11), 2015
PMID: 26311854
Genomic epidemiology of age-associated meningococcal lineages in national surveillance: an observational cohort study.
Hill DM, Lucidarme J, Gray SJ, Newbold LS, Ure R, Brehony C, Harrison OB, Bray JE, Jolley KA, Bratcher HB, Parkhill J, Tang CM, Borrow R, Maiden MC., Lancet Infect Dis 15(12), 2015
PMID: 26515523
Utility of detection of telaprevir-resistant variants for prediction of efficacy of treatment of hepatitis C virus genotype 1 infection.
Akuta N, Suzuki F, Fukushima T, Kawamura Y, Sezaki H, Suzuki Y, Hosaka T, Kobayashi M, Hara T, Kobayashi M, Saitoh S, Arase Y, Ikeda K, Kumada H., J Clin Microbiol 52(1), 2014
PMID: 24197875
Rapid single-colony whole-genome sequencing of bacterial pathogens.
Köser CU, Fraser LJ, Ioannou A, Becq J, Ellington MJ, Holden MT, Reuter S, Török ME, Bentley SD, Parkhill J, Gormley NA, Smith GP, Peacock SJ., J Antimicrob Chemother 69(5), 2014
PMID: 24370932
Using multilocus sequence typing to study bacterial variation: prospects in the genomic era.
Jolley KA, Maiden MC., Future Microbiol 9(5), 2014
PMID: 24957089
A ddRAD-based genetic map and its integration with the genome assembly of Japanese eel (Anguilla japonica) provides insights into genome evolution after the teleost-specific genome duplication.
Kai W, Nomura K, Fujiwara A, Nakamura Y, Yasuike M, Ojima N, Masaoka T, Ozaki A, Kazeto Y, Gen K, Nagao J, Tanaka H, Kobayashi T, Ototake M., BMC Genomics 15(), 2014
PMID: 24669946
Whole-genome-based Mycobacterium tuberculosis surveillance: a standardized, portable, and expandable approach.
Kohl TA, Diel R, Harmsen D, Rothgänger J, Walter KM, Merker M, Weniger T, Niemann S., J Clin Microbiol 52(7), 2014
PMID: 24789177
Evolution of simeprevir-resistant variants over time by ultra-deep sequencing in HCV genotype 1b.
Akuta N, Suzuki F, Sezaki H, Suzuki Y, Hosaka T, Kobayashi M, Kobayashi M, Saitoh S, Ikeda K, Kumada H., J Med Virol 86(8), 2014
PMID: 24797623
WGS Analysis and Interpretation in Clinical and Public Health Microbiology Laboratories: What Are the Requirements and How Do Existing Tools Compare?
Wyres KL, Conway TC, Garg S, Queiroz C, Reumann M, Holt K, Rusu LI., Pathogens 3(2), 2014
PMID: 25437808
Evaluation and optimisation of indel detection workflows for ion torrent sequencing of the BRCA1 and BRCA2 genes.
Yeo ZX, Wong JC, Rozen SG, Lee AS., BMC Genomics 15(), 2014
PMID: 24962530
An extended multi-locus molecular typing schema for Streptococcus pneumoniae demonstrates that a limited number of capsular switch events is responsible for serotype heterogeneity of closely related strains from different countries.
Crisafulli G, Guidotti S, Muzzi A, Torricelli G, Moschioni M, Masignani V, Censini S, Donati C., Infect Genet Evol 13(), 2013
PMID: 23022733
Genetic and antigenic characterization of invasive endemic serogroup B Neisseria meningitidis from Ontario, Canada, in 2001-2010.
Jamieson FB, Rawte P, Deeks SL, Zhou J, Law DK, Deng S, Tsang RS., J Med Microbiol 62(pt 1), 2013
PMID: 23038803
Combining highly multiplexed PCR with semiconductor-based sequencing for rapid cancer genotyping.
Beadling C, Neff TL, Heinrich MC, Rhodes K, Thornton M, Leamon J, Andersen M, Corless CL., J Mol Diagn 15(2), 2013
PMID: 23274167
Semiconductor-based DNA sequencing of histone modification states.
Cheng CS, Rai K, Garber M, Hollinger A, Robbins D, Anderson S, Macbeth A, Tzou A, Carneiro MO, Raychowdhury R, Russ C, Hacohen N, Gershenwald JE, Lennon N, Nusbaum C, Chin L, Regev A, Amit I., Nat Commun 4(), 2013
PMID: 24157732
Automated extraction of typing information for bacterial pathogens from whole genome sequence data: Neisseria meningitidis as an exemplar.
Jolley KA, Maiden MC., Euro Surveill 18(4), 2013
PMID: 23369391
Pathogen typing in the genomics era: MLST and the future of molecular epidemiology.
Pérez-Losada M, Cabezas P, Castro-Nallar E, Crandall KA., Infect Genet Evol 16(), 2013
PMID: 23357583
Emergence of telaprevir-resistant variants detected by ultra-deep sequencing after triple therapy in patients infected with HCV genotype 1.
Akuta N, Suzuki F, Seko Y, Kawamura Y, Sezaki H, Suzuki Y, Hosaka T, Kobayashi M, Hara T, Kobayashi M, Saitoh S, Arase Y, Ikeda K, Kumada H., J Med Virol 85(6), 2013
PMID: 23588728
Prediction of treatment efficacy and telaprevir-resistant variants after triple therapy in patients infected with hepatitis C virus genotype 1.
Akuta N, Suzuki F, Fukushima T, Kawamura Y, Sezaki H, Suzuki Y, Hosaka T, Kobayashi M, Hara T, Kobayashi M, Saitoh S, Arase Y, Ikeda K, Kumada H., J Clin Microbiol 51(9), 2013
PMID: 23784126
Clinical validation of a next-generation sequencing screen for mutational hotspots in 46 cancer-related genes.
Singh RR, Patel KP, Routbort MJ, Reddy NG, Barkoh BA, Handal B, Kanagal-Shamanna R, Greaves WO, Medeiros LJ, Aldape KD, Luthra R., J Mol Diagn 15(5), 2013
PMID: 23810757
Towards clinical molecular diagnosis of inherited cardiac conditions: a comparison of bench-top genome DNA sequencers.
Li X, Buckton AJ, Wilkinson SL, John S, Walsh R, Novotny T, Valaskova I, Gupta M, Game L, Barton PJ, Cook SA, Ware JS., PLoS One 8(7), 2013
PMID: 23861798
Rapid bacterial whole-genome sequencing to enhance diagnostic and public health microbiology.
Reuter S, Ellington MJ, Cartwright EJ, Köser CU, Török ME, Gouliouris T, Harris SR, Brown NM, Holden MT, Quail M, Parkhill J, Smith GP, Bentley SD, Peacock SJ., JAMA Intern Med 173(15), 2013
PMID: 23857503
The detection of microRNA associated with Alzheimer's disease in biological fluids using next-generation sequencing technologies.
Cheng L, Quek CY, Sun X, Bellingham SA, Hill AF., Front Genet 4(), 2013
PMID: 23964286
Draft Genome Sequence of Lignocellulose-Degrading Thermophilic Bacterium Geobacillus sp. Strain WSUCF1.
Bhalla A, Kainth AS, Sani RK., Genome Announc 1(4), 2013
PMID: 23950119
Genomic comparative analysis and gene function prediction in infectious diseases: application to the investigation of a meningitis outbreak.
Lavezzo E, Toppo S, Franchin E, Di Camillo B, Finotello F, Falda M, Manganelli R, Palù G, Barzon L., BMC Infect Dis 13(), 2013
PMID: 24252229
Resolution of a meningococcal disease outbreak from whole-genome sequence data with rapid Web-based analysis methods.
Jolley KA, Hill DM, Bratcher HB, Harrison OB, Feavers IM, Parkhill J, Maiden MC., J Clin Microbiol 50(9), 2012
PMID: 22785191
Current mutation discovery approaches in Retinitis Pigmentosa.
Anasagasti A, Irigoyen C, Barandika O, López de Munain A, Ruiz-Ederra J., Vision Res 75(), 2012
PMID: 23022136
Quality control of next-generation sequencing library through an integrative digital microfluidic platform.
Thaitrong N, Kim H, Renzi RF, Bartsch MS, Meagher RJ, Patel KD., Electrophoresis 33(23), 2012
PMID: 23135807

49 References

Daten bereitgestellt von Europe PubMed Central.

A phase 1 study of a meningococcal native outer membrane vesicle vaccine made from a group B strain with deleted lpxL1 and synX, over-expressed factor H binding protein, two PorAs and stabilized OpcA expression.
Keiser PB, Biggs-Cicatelli S, Moran EE, Schmiel DH, Pinto VB, Burden RE, Miller LB, Moon JE, Bowden RA, Cummings JF, Zollinger WD., Vaccine 29(7), 2011
PMID: 21199704
AgdbNet - antigen sequence database software for bacterial typing.
Jolley KA, Maiden MC., BMC Bioinformatics 7(), 2006
PMID: 16790057
An integrated semiconductor device enabling non-optical genome sequencing.
Rothberg JM, Hinz W, Rearick TM, Schultz J, Mileski W, Davey M, Leamon JH, Johnson K, Milgrew MJ, Edwards M, Hoon J, Simons JF, Marran D, Myers JW, Davidson JF, Branting A, Nobile JR, Puc BP, Light D, Clark TA, Huber M, Branciforte JT, Stoner IB, Cawley SE, Lyons M, Fu Y, Homer N, Sedova M, Miao X, Reed B, Sabina J, Feierstein E, Schorn M, Alanjary M, Dimalanta E, Dressman D, Kasinskas R, Sokolsky T, Fidanza JA, Namsaraev E, McKernan KJ, Williams A, Roth GT, Bustillo J., Nature 475(7356), 2011
PMID: 21776081
Prospective genomic characterization of the German enterohemorrhagic Escherichia coli O104:H4 outbreak by rapid next generation sequencing technology.
Mellmann A, Harmsen D, Cummings CA, Zentz EB, Leopold SR, Rico A, Prior K, Szczepanowski R, Ji Y, Zhang W, McLaughlin SF, Henkhaus JK, Leopold B, Bielaszewska M, Prager R, Brzoska PM, Moore RL, Guenther S, Rothberg JM, Karch H., PLoS ONE 6(7), 2011
PMID: 21799941
Molecular typing methods for outbreak detection and surveillance of invasive disease caused by Neisseria meningitidis, Haemophilus influenzae and Streptococcus pneumoniae, a review.
Harrison OB, Brueggemann AB, Caugant DA, van der Ende A, Frosch M, Gray S, Heuberger S, Krizova P, Olcen P, Slack M, Taha MK, Maiden MC., Microbiology (Reading, Engl.) 157(Pt 8), 2011
PMID: 21622526
Evidence for indirect nosocomial transmission of Neisseria meningitidis resulting in two cases of invasive meningococcal disease.
Elias J; Health Office in the Rural District Office Wartburgkreis, Claus H, Frosch M, Vogel U., J. Clin. Microbiol. 44(11), 2006
PMID: 16943350
IS1301 fingerprint analysis of Neisseria meningitidis strains belonging to the ET-15 clone.
Elias J, Vogel U., J. Clin. Microbiol. 45(1), 2006
PMID: 17093016
Molecular typing of meningococci: recommendations for target choice and nomenclature.
Jolley KA, Brehony C, Maiden MC., FEMS Microbiol. Rev. 31(1), 2006
PMID: 17168996
Spatiotemporal analysis of invasive meningococcal disease, Germany.
Elias J, Harmsen D, Claus H, Hellenbrand W, Frosch M, Vogel U., Emerging Infect. Dis. 12(11), 2006
PMID: 17283618
Immunogenicity of a combination vaccine containing pneumococcal conjugates and meningococcal PorA OMVs.
van den Dobbelsteen GP, van Dijken HH, Pillai S, van Alphen L., Vaccine 25(13), 2006
PMID: 17023098
Target gene sequencing to characterize the penicillin G susceptibility of Neisseria meningitidis.
Taha MK, Vazquez JA, Hong E, Bennett DE, Bertrand S, Bukovski S, Cafferkey MT, Carion F, Christensen JJ, Diggle M, Edwards G, Enriquez R, Fazio C, Frosch M, Heuberger S, Hoffmann S, Jolley KA, Kadlubowski M, Kechrid A, Kesanopoulos K, Kriz P, Lambertsen L, Levenet I, Musilek M, Paragi M, Saguer A, Skoczynska A, Stefanelli P, Thulin S, Tzanakaki G, Unemo M, Vogel U, Zarantonelli ML., Antimicrob. Agents Chemother. 51(8), 2007
PMID: 17517841
Accurate whole human genome sequencing using reversible terminator chemistry.
Bentley DR, Balasubramanian S, Swerdlow HP, Smith GP, Milton J, Brown CG, Hall KP, Evers DJ, Barnes CL, Bignell HR, Boutell JM, Bryant J, Carter RJ, Keira Cheetham R, Cox AJ, Ellis DJ, Flatbush MR, Gormley NA, Humphray SJ, Irving LJ, Karbelashvili MS, Kirk SM, Li H, Liu X, Maisinger KS, Murray LJ, Obradovic B, Ost T, Parkinson ML, Pratt MR, Rasolonjatovo IM, Reed MT, Rigatti R, Rodighiero C, Ross MT, Sabot A, Sankar SV, Scally A, Schroth GP, Smith ME, Smith VP, Spiridou A, Torrance PE, Tzonev SS, Vermaas EH, Walter K, Wu X, Zhang L, Alam MD, Anastasi C, Aniebo IC, Bailey DM, Bancarz IR, Banerjee S, Barbour SG, Baybayan PA, Benoit VA, Benson KF, Bevis C, Black PJ, Boodhun A, Brennan JS, Bridgham JA, Brown RC, Brown AA, Buermann DH, Bundu AA, Burrows JC, Carter NP, Castillo N, Chiara E Catenazzi M, Chang S, Neil Cooley R, Crake NR, Dada OO, Diakoumakos KD, Dominguez-Fernandez B, Earnshaw DJ, Egbujor UC, Elmore DW, Etchin SS, Ewan MR, Fedurco M, Fraser LJ, Fuentes Fajardo KV, Scott Furey W, George D, Gietzen KJ, Goddard CP, Golda GS, Granieri PA, Green DE, Gustafson DL, Hansen NF, Harnish K, Haudenschild CD, Heyer NI, Hims MM, Ho JT, Horgan AM, Hoschler K, Hurwitz S, Ivanov DV, Johnson MQ, James T, Huw Jones TA, Kang GD, Kerelska TH, Kersey AD, Khrebtukova I, Kindwall AP, Kingsbury Z, Kokko-Gonzales PI, Kumar A, Laurent MA, Lawley CT, Lee SE, Lee X, Liao AK, Loch JA, Lok M, Luo S, Mammen RM, Martin JW, McCauley PG, McNitt P, Mehta P, Moon KW, Mullens JW, Newington T, Ning Z, Ling Ng B, Novo SM, O'Neill MJ, Osborne MA, Osnowski A, Ostadan O, Paraschos LL, Pickering L, Pike AC, Pike AC, Chris Pinkard D, Pliskin DP, Podhasky J, Quijano VJ, Raczy C, Rae VH, Rawlings SR, Chiva Rodriguez A, Roe PM, Rogers J, Rogert Bacigalupo MC, Romanov N, Romieu A, Roth RK, Rourke NJ, Ruediger ST, Rusman E, Sanches-Kuiper RM, Schenker MR, Seoane JM, Shaw RJ, Shiver MK, Short SW, Sizto NL, Sluis JP, Smith MA, Ernest Sohna Sohna J, Spence EJ, Stevens K, Sutton N, Szajkowski L, Tregidgo CL, Turcatti G, Vandevondele S, Verhovsky Y, Virk SM, Wakelin S, Walcott GC, Wang J, Worsley GJ, Yan J, Yau L, Zuerlein M, Rogers J, Mullikin JC, Hurles ME, McCooke NJ, West JS, Oaks FL, Lundberg PL, Klenerman D, Durbin R, Smith AJ., Nature 456(7218), 2008
PMID: 18987734
Population genomics: diversity and virulence in the Neisseria.
Maiden MC., Curr. Opin. Microbiol. 11(5), 2008
PMID: 18822386
Prevalence and sequence variations of the genes encoding the five antigens included in the novel 5CVMB vaccine covering group B meningococcal disease.
Jacobsson S, Hedberg ST, Molling P, Unemo M, Comanducci M, Rappuoli R, Olcen P., Vaccine 27(10), 2009
PMID: 19162117
Distribution and genetic variability of three vaccine components in a panel of strains representative of the diversity of serogroup B meningococcus.
Bambini S, Muzzi A, Olcen P, Rappuoli R, Pizza M, Comanducci M., Vaccine 27(21), 2009
PMID: 19428890
Sequence diversity of the factor H binding protein vaccine candidate in epidemiologically relevant strains of serogroup B Neisseria meningitidis.
Murphy E, Andrew L, Lee KL, Dilts DA, Nunez L, Fink PS, Ambrose K, Borrow R, Findlow J, Taha MK, Deghmane AE, Kriz P, Musilek M, Kalmusova J, Caugant DA, Alvestad T, Mayer LW, Sacchi CT, Wang X, Martin D, von Gottberg A, du Plessis M, Klugman KP, Anderson AS, Jansen KU, Zlotnick GW, Hoiseth SK., J. Infect. Dis. 200(3), 2009
PMID: 19534597
Genealogical typing of Neisseria meningitidis.
Didelot X, Urwin R, Maiden MC, Falush D., Microbiology (Reading, Engl.) 155(Pt 10), 2009
PMID: 19643763
Communicable diseases prioritized for surveillance and epidemiological research: results of a standardized prioritization procedure in Germany, 2011.
Balabanova Y, Gilsdorf A, Buda S, Burger R, Eckmanns T, Gartner B, Gross U, Haas W, Hamouda O, Hubner J, Janisch T, Kist M, Kramer MH, Ledig T, Mielke M, Pulz M, Stark K, Suttorp N, Ulbrich U, Wichmann O, Krause G., PLoS ONE 6(10), 2011
PMID: 21991334
European efforts to harmonize typing of meningococci.
Vogel U., Int. J. Med. Microbiol. 301(8), 2011
PMID: 21992745
Complete genome sequence of Neisseria meningitidis serogroup B strain MC58.
Tettelin H, Saunders NJ, Heidelberg J, Jeffries AC, Nelson KE, Eisen JA, Ketchum KA, Hood DW, Peden JF, Dodson RJ, Nelson WC, Gwinn ML, DeBoy R, Peterson JD, Hickey EK, Haft DH, Salzberg SL, White O, Fleischmann RD, Dougherty BA, Mason T, Ciecko A, Parksey DS, Blair E, Cittone H, Clark EB, Cotton MD, Utterback TR, Khouri H, Qin H, Vamathevan J, Gill J, Scarlato V, Masignani V, Pizza M, Grandi G, Sun L, Smith HO, Fraser CM, Moxon ER, Rappuoli R, Venter JC., Science 287(5459), 2000
PMID: 10710307
Molecular basis for distinction of the ET-15 clone within the ET-37 complex of Neisseria meningitidis.
Vogel U, Claus H, Frosch M, Caugant DA., J. Clin. Microbiol. 38(2), 2000
PMID: 10722324
Carried meningococci in the Czech Republic: a diverse recombining population.
Jolley KA, Kalmusova J, Feil EJ, Gupta S, Musilek M, Kriz P, Maiden MC., J. Clin. Microbiol. 38(12), 2000
PMID: 11101585
Meningococcal disease.
Rosenstein NE, Perkins BA, Stephens DS, Popovic T, Hughes JM., N. Engl. J. Med. 344(18), 2001
PMID: 11333996
A 10-year serogroup B meningococcal disease epidemic in New Zealand: descriptive epidemiology, 1991-2000.
Baker MG, Martin DR, Kieft CE, Lennon D., J Paediatr Child Health 37(5), 2001
PMID: 11885731
Characterization of fHbp, nhba (gna2132), nadA, porA, sequence type (ST), and genomic presence of IS1301 in group B meningococcal ST269 clonal complex isolates from England and Wales.
Lucidarme J, Comanducci M, Findlow J, Gray SJ, Kaczmarski EB, Guiver M, Kugelberg E, Vallely PJ, Oster P, Pizza M, Bambini S, Muzzi A, Tang CM, Borrow R., J. Clin. Microbiol. 47(11), 2009
PMID: 19759227
Molecular characterization of resistance to rifampicin in clinical isolates of Neisseria meningitidis.
Skoczynska A, Ruckly C, Hong E, Taha MK., Clin. Microbiol. Infect. 15(12), 2009
PMID: 19456827
Variation of the factor H-binding protein of Neisseria meningitidis.
Brehony C, Wilson DJ, Maiden MC., Microbiology (Reading, Engl.) 155(Pt 12), 2009
PMID: 19729409
Neisseria meningitidis GNA2132, a heparin-binding protein that induces protective immunity in humans.
Serruto D, Spadafina T, Ciucchi L, Lewis LA, Ram S, Tontini M, Santini L, Biolchi A, Seib KL, Giuliani MM, Donnelly JJ, Berti F, Savino S, Scarselli M, Costantino P, Kroll JS, O'Dwyer C, Qiu J, Plaut AG, Moxon R, Rappuoli R, Pizza M, Arico B., Proc. Natl. Acad. Sci. U.S.A. 107(8), 2010
PMID: 20133713
Vaccine preventability of meningococcal clone, Greater Aachen Region, Germany.
Elias J, Schouls LM, van de Pol I, Keijzers WC, Martin DR, Glennie A, Oster P, Frosch M, Vogel U, van der Ende A., Emerging Infect. Dis. 16(3), 2010
PMID: 20202422
Advances in the development of vaccines against Neisseria meningitidis.
Tan LK, Carlone GM, Borrow R., N. Engl. J. Med. 362(16), 2010
PMID: 20410516
An outer membrane receptor of Neisseria meningitidis involved in zinc acquisition with vaccine potential.
Stork M, Bos MP, Jongerius I, de Kok N, Schilders I, Weynants VE, Poolman JT, Tommassen J., PLoS Pathog. 6(), 2010
PMID: 20617164
Broad vaccine coverage predicted for a bivalent recombinant factor H binding protein based vaccine to prevent serogroup B meningococcal disease.
Jiang HQ, Hoiseth SK, Harris SL, McNeil LK, Zhu D, Tan C, Scott AA, Alexander K, Mason K, Miller L, DaSilva I, Mack M, Zhao XJ, Pride MW, Andrew L, Murphy E, Hagen M, French R, Arora A, Jones TR, Jansen KU, Zlotnick GW, Anderson AS., Vaccine 28(37), 2010
PMID: 20619376
Multicenter study for defining the breakpoint for rifampin resistance in Neisseria meningitidis by rpoB sequencing.
Taha MK, Hedberg ST, Szatanik M, Hong E, Ruckly C, Abad R, Bertrand S, Carion F, Claus H, Corso A, Enriquez R, Heuberger S, Hryniewicz W, Jolley KA, Kriz P, Mollerach M, Musilek M, Neri A, Olcen P, Pana M, Skoczynska A, Sorhouet Pereira C, Stefanelli P, Tzanakaki G, Unemo M, Vazquez JA, Vogel U, Wasko I., Antimicrob. Agents Chemother. 54(9), 2010
PMID: 20606072
Molecular epidemiology of meningococci: application of DNA sequence typing.
Vogel U., Int. J. Med. Microbiol. 300(7), 2010
PMID: 20537945
BIGSdb: Scalable analysis of bacterial genome variation at the population level.
Jolley KA, Maiden MC., BMC Bioinformatics 11(), 2010
PMID: 21143983
NadA, a novel vaccine candidate of Neisseria meningitidis.
Comanducci M, Bambini S, Brunelli B, Adu-Bobie J, Arico B, Capecchi B, Giuliani MM, Masignani V, Santini L, Savino S, Granoff DM, Caugant DA, Pizza M, Rappuoli R, Mora M., J. Exp. Med. 195(11), 2002
PMID: 12045242
Experimentally revised repertoire of putative contingency loci in Neisseria meningitidis strain MC58: evidence for a novel mechanism of phase variation.
Martin P, van de Ven T, Mouchel N, Jeffries AC, Hood DW, Moxon ER., Mol. Microbiol. 50(1), 2003
PMID: 14507378
Versatile and open software for comparing large genomes.
Kurtz S, Phillippy A, Delcher AL, Smoot M, Shumway M, Antonescu C, Salzberg SL., Genome Biol. 5(2), 2004
PMID: 14759262
Using the miraEST assembler for reliable and automated mRNA transcript assembly and SNP detection in sequenced ESTs.
Chevreux B, Pfisterer T, Drescher B, Driesel AJ, Muller WE, Wetter T, Suhai S., Genome Res. 14(6), 2004
PMID: 15140833
mlstdbNet - distributed multi-locus sequence typing (MLST) databases.
Jolley KA, Chan MS, Maiden MC., BMC Bioinformatics 5(), 2004
PMID: 15230973
Distribution of surface protein variants among hyperinvasive meningococci: implications for vaccine design.
Urwin R, Russell JE, Thompson EA, Holmes EC, Feavers IM, Maiden MC., Infect. Immun. 72(10), 2004
PMID: 15385499
Emergence of a virulent clone of Neisseria meningitidis serotype 2a that is associated with meningococcal group C disease in Canada.
Ashton FE, Ryan JA, Borczyk A, Caugant DA, Mancino L, Huang D., J. Clin. Microbiol. 29(11), 1991
PMID: 1774254
Capsule switching of Neisseria meningitidis.
Swartley JS, Marfin AA, Edupuganti S, Liu LJ, Cieslak P, Perkins B, Wenger JD, Stephens DS., Proc. Natl. Acad. Sci. U.S.A. 94(1), 1997
PMID: 8990198
Multilocus sequence typing: a portable approach to the identification of clones within populations of pathogenic microorganisms.
Maiden MC, Bygraves JA, Feil E, Morelli G, Russell JE, Urwin R, Zhang Q, Zhou J, Zurth K, Caugant DA, Feavers IM, Achtman M, Spratt BG., Proc. Natl. Acad. Sci. U.S.A. 95(6), 1998
PMID: 9501229
Genome sequencing in microfabricated high-density picolitre reactors.
Margulies M, Egholm M, Altman WE, Attiya S, Bader JS, Bemben LA, Berka J, Braverman MS, Chen YJ, Chen Z, Dewell SB, Du L, Fierro JM, Gomes XV, Godwin BC, He W, Helgesen S, Ho CH, Ho CH, Irzyk GP, Jando SC, Alenquer ML, Jarvie TP, Jirage KB, Kim JB, Knight JR, Lanza JR, Leamon JH, Lefkowitz SM, Lei M, Li J, Lohman KL, Lu H, Makhijani VB, McDade KE, McKenna MP, Myers EW, Nickerson E, Nobile JR, Plant R, Puc BP, Ronan MT, Roth GT, Sarkis GJ, Simons JF, Simpson JW, Srinivasan M, Tartaro KR, Tomasz A, Vogt KA, Volkmer GA, Wang SH, Wang Y, Weiner MP, Yu P, Begley RF, Rothberg JM., Nature 437(7057), 2005
PMID: 16056220
The VR2 epitope on the PorA P1.7-2,4 protein is the major target for the immune response elicited by the strain-specific group B meningococcal vaccine MeNZB.
Martin DR, Ruijne N, McCallum L, O'Hallahan J, Oster P., Clin. Vaccine Immunol. 13(4), 2006
PMID: 16603616
PulseNet USA: a five-year update.
Gerner-Smidt P, Hise K, Kincaid J, Hunter S, Rolando S, Hyytia-Trees E, Ribot EM, Swaminathan B; Pulsenet Taskforce., Foodborne Pathog. Dis. 3(1), 2006
PMID: 16602975
A universal vaccine for serogroup B meningococcus.
Giuliani MM, Adu-Bobie J, Comanducci M, Arico B, Savino S, Santini L, Brunelli B, Bambini S, Biolchi A, Capecchi B, Cartocci E, Ciucchi L, Di Marcello F, Ferlicca F, Galli B, Luzzi E, Masignani V, Serruto D, Veggi D, Contorni M, Morandi M, Bartalesi A, Cinotti V, Mannucci D, Titta F, Ovidi E, Welsch JA, Granoff D, Rappuoli R, Pizza M., Proc. Natl. Acad. Sci. U.S.A. 103(29), 2006
PMID: 16825336
Vaccine development against Neisseria meningitidis.
Vogel U, Claus H., Microb Biotechnol 4(1), 2011
PMID: 21255369
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