Genomics of IncP-1 antibiotic resistance plasmids isolated from wastewater treatment plants provides evidence for a widely accessible drug resistance gene pool

Schlüter A, Szczepanowski R, Pühler A, Top EM (2007)

Zeitschriftenaufsatz | Veröffentlicht | Englisch
Es wurden keine Dateien hochgeladen. Nur Publikationsnachweis!
Abstract / Bemerkung
The dramatic spread of antibiotic resistance is a crisis in the treatment of infectious diseases that affect humans. Several studies suggest that wastewater treatment plants (WWTP) are reservoirs for diverse mobile antibiotic resistance elements. This review summarizes findings derived from genomic analysis of IncP-1 resistance plasmids isolated from WWTP bacteria. Plasmids that belong to the IncP-1 group are self-transmissible, and transfer to and replicate in a wide range of hosts. Their backbone functions are described with respect to their impact on vegetative replication, stable maintenance and inheritance, mobility and plasmid control. Accessory genetic modules, mainly representing mobile genetic elements, are integrated in-between functional plasmid backbone modules. These elements carry determinants conferring resistance to nearly all clinically relevant antimicrobial drug classes, to heavy metals, and quaternary ammonium compounds used as disinfectants. All plasmids analysed here contain integrons that potentially facilitate integration, exchange and dissemination of resistance gene cassettes. Comparative genomics of accessory modules located on plasmids from WWTP and corresponding modules previously identified in other bacterial genomes revealed that animal, human and plant pathogens and other bacteria isolated from different habitats share a common pool of resistance determinants.
horizontal gene transfer; integron; transposable element; broad-host-range plasmid; drug resistance
Page URI


Schlüter A, Szczepanowski R, Pühler A, Top EM. Genomics of IncP-1 antibiotic resistance plasmids isolated from wastewater treatment plants provides evidence for a widely accessible drug resistance gene pool. FEMS MICROBIOLOGY REVIEWS. 2007;31(4):449-477.
Schlüter, A., Szczepanowski, R., Pühler, A., & Top, E. M. (2007). Genomics of IncP-1 antibiotic resistance plasmids isolated from wastewater treatment plants provides evidence for a widely accessible drug resistance gene pool. FEMS MICROBIOLOGY REVIEWS, 31(4), 449-477.
Schlüter, Andreas, Szczepanowski, Rafael, Pühler, Alfred, and Top, Eva M. 2007. “Genomics of IncP-1 antibiotic resistance plasmids isolated from wastewater treatment plants provides evidence for a widely accessible drug resistance gene pool”. FEMS MICROBIOLOGY REVIEWS 31 (4): 449-477.
Schlüter, A., Szczepanowski, R., Pühler, A., and Top, E. M. (2007). Genomics of IncP-1 antibiotic resistance plasmids isolated from wastewater treatment plants provides evidence for a widely accessible drug resistance gene pool. FEMS MICROBIOLOGY REVIEWS 31, 449-477.
Schlüter, A., et al., 2007. Genomics of IncP-1 antibiotic resistance plasmids isolated from wastewater treatment plants provides evidence for a widely accessible drug resistance gene pool. FEMS MICROBIOLOGY REVIEWS, 31(4), p 449-477.
A. Schlüter, et al., “Genomics of IncP-1 antibiotic resistance plasmids isolated from wastewater treatment plants provides evidence for a widely accessible drug resistance gene pool”, FEMS MICROBIOLOGY REVIEWS, vol. 31, 2007, pp. 449-477.
Schlüter, A., Szczepanowski, R., Pühler, A., Top, E.M.: Genomics of IncP-1 antibiotic resistance plasmids isolated from wastewater treatment plants provides evidence for a widely accessible drug resistance gene pool. FEMS MICROBIOLOGY REVIEWS. 31, 449-477 (2007).
Schlüter, Andreas, Szczepanowski, Rafael, Pühler, Alfred, and Top, Eva M. “Genomics of IncP-1 antibiotic resistance plasmids isolated from wastewater treatment plants provides evidence for a widely accessible drug resistance gene pool”. FEMS MICROBIOLOGY REVIEWS 31.4 (2007): 449-477.

151 Zitationen in Europe PMC

Daten bereitgestellt von Europe PubMed Central.

Wastewater treatment plant resistomes are shaped by bacterial composition, genetic exchange, and upregulated expression in the effluent microbiomes.
Ju F, Beck K, Yin X, Maccagnan A, McArdell CS, Singer HP, Johnson DR, Zhang T, Bürgmann H., ISME J 13(2), 2019
PMID: 30250051
Mobile antibiotic resistome in wastewater treatment plants revealed by Nanopore metagenomic sequencing.
Che Y, Xia Y, Liu L, Li AD, Yang Y, Zhang T., Microbiome 7(1), 2019
PMID: 30898140
Antibiotic resistance genes show enhanced mobilization through suspended growth and biofilm-based wastewater treatment processes.
Petrovich M, Chu B, Wright D, Griffin J, Elfeki M, Murphy BT, Poretsky R, Wells G., FEMS Microbiol Ecol 94(5), 2018
PMID: 29534199
The Transferable Resistome of Produce.
Blau K, Bettermann A, Jechalke S, Fornefeld E, Vanrobaeys Y, Stalder T, Top EM, Smalla K., MBio 9(6), 2018
PMID: 30401772
Bacteria and fungi inactivation by photocatalysis under UVA irradiation: liquid and gas phase.
Rodrigues-Silva C, Miranda SM, Lopes FVS, Silva M, Dezotti M, Silva AMT, Faria JL, Boaventura RAR, Vilar VJP, Pinto E., Environ Sci Pollut Res Int 24(7), 2017
PMID: 27357708
Functional Repertoire of Antibiotic Resistance Genes in Antibiotic Manufacturing Effluents and Receiving Freshwater Sediments.
González-Plaza JJ, Šimatović A, Milaković M, Bielen A, Wichmann F, Udiković-Kolić N., Front Microbiol 8(), 2017
PMID: 29387045
Occurrence and elimination of antibiotic resistance genes in a long-term operation integrated surface flow constructed wetland.
Fang H, Zhang Q, Nie X, Chen B, Xiao Y, Zhou Q, Liao W, Liang X., Chemosphere 173(), 2017
PMID: 28107719
Characterizing the Multidrug Resistance of non-O157 Shiga Toxin-Producing Escherichia coli Isolates from Cattle Farms and Abattoirs.
Kennedy CA, Fanning S, Karczmarczyk M, Byrne B, Monaghan Á, Bolton D, Sweeney T., Microb Drug Resist 23(6), 2017
PMID: 28304216
A Three-Year Follow-Up Study of Antibiotic and Metal Residues, Antibiotic Resistance and Resistance Genes, Focusing on Kshipra-A River Associated with Holy Religious Mass-Bathing in India: Protocol Paper.
Diwan V, Purohit M, Chandran S, Parashar V, Shah H, Mahadik VK, Stålsby Lundborg C, Tamhankar AJ., Int J Environ Res Public Health 14(6), 2017
PMID: 28555050
Mobile genetic elements in Neisseria gonorrhoeae: movement for change.
Cehovin A, Lewis SB., Pathog Dis 75(6), 2017
PMID: 28645177
Persistence and reversal of plasmid-mediated antibiotic resistance.
Lopatkin AJ, Meredith HR, Srimani JK, Pfeiffer C, Durrett R, You L., Nat Commun 8(1), 2017
PMID: 29162798
Effects of antibiotic resistance genes on the performance and stability of different microbial aggregates in a granular sequencing batch reactor.
Zou W, Xue B, Zhi W, Zhao T, Yang D, Qiu Z, Shen Z, Li J, Zhang B, Wang J., J Hazard Mater 304(), 2016
PMID: 26590870
Diversification of broad host range plasmids correlates with the presence of antibiotic resistance genes.
Li X, Wang Y, Brown CJ, Yao F, Jiang Y, Top EM, Li H., FEMS Microbiol Ecol 92(1), 2016
PMID: 26635412
High Diversity of CTX-M Extended-Spectrum β-Lactamases in Municipal Wastewater and Urban Wetlands.
Borgogna TR, Borgogna JL, Mielke JA, Brown CJ, Top EM, Botts RT, Cummings DE., Microb Drug Resist 22(4), 2016
PMID: 26670020
Characteristics of extended-spectrum β-lactamase (ESBL)- and pAmpC beta-lactamase-producing Enterobacteriaceae of water samples in Tunisia.
Ben Said L, Jouini A, Alonso CA, Klibi N, Dziri R, Boudabous A, Ben Slama K, Torres C., Sci Total Environ 550(), 2016
PMID: 26871556
"Every Gene Is Everywhere but the Environment Selects": Global Geolocalization of Gene Sharing in Environmental Samples through Network Analysis.
Fondi M, Karkman A, Tamminen MV, Bosi E, Virta M, Fani R, Alm E, McInerney JO., Genome Biol Evol 8(5), 2016
PMID: 27190206
Household medical waste disposal policy in Israel.
Barnett-Itzhaki Z, Berman T, Grotto I, Schwartzberg E., Isr J Health Policy Res 5(), 2016
PMID: 27766144
Abundance of antibiotic resistance genes in five municipal wastewater treatment plants in the Monastir Governorate, Tunisia.
Rafraf ID, Lekunberri I, Sànchez-Melsió A, Aouni M, Borrego CM, Balcázar JL., Environ Pollut 219(), 2016
PMID: 27814552
Phenotypic and genetic characterization of multidrug-resistant Staphylococcus aureus in the tropics of Southeast Asia.
Zulkeflle SN, Yusaimi YA, Sugiura N, Iwamoto K, Goto M, Utsumi M, Othman NB, Zakaria Z, Hara H., Microbiology 162(12), 2016
PMID: 27902427
Conjugative multiple-antibiotic resistance plasmids in Escherichia coli isolated from environmental waters contaminated by human faecal wastes.
Laroche-Ajzenberg E, Flores Ribeiro A, Bodilis J, Riah W, Buquet S, Chaftar N, Pawlak B., J Appl Microbiol 118(2), 2015
PMID: 25387599
Plasmid Detection, Characterization, and Ecology.
Smalla K, Jechalke S, Top EM., Microbiol Spectr 3(1), 2015
PMID: 26104560
Effects of 100 years wastewater irrigation on resistance genes, class 1 integrons and IncP-1 plasmids in Mexican soil.
Jechalke S, Broszat M, Lang F, Siebe C, Smalla K, Grohmann E., Front Microbiol 6(), 2015
PMID: 25784901
Ceftriaxone-resistant Salmonella enterica serotype typhimurium sequence type 313 from Kenyan patients is associated with the blaCTX-M-15 gene on a novel IncHI2 plasmid.
Kariuki S, Okoro C, Kiiru J, Njoroge S, Omuse G, Langridge G, Kingsley RA, Dougan G, Revathi G., Antimicrob Agents Chemother 59(6), 2015
PMID: 25779570
Characterization of a collection of plasmid-containing bacteria isolated from an on-farm biopurification system used for pesticide removal.
Martini MC, Albicoro FJ, Nour E, Schlüter A, van Elsas JD, Springael D, Smalla K, Pistorio M, Lagares A, Del Papa MF., Plasmid 80(), 2015
PMID: 25957823
Coliform bacteria isolated from recreational lakes carry class 1 and class 2 integrons and virulence-associated genes.
Koczura R, Krysiak N, Taraszewska A, Mokracka J., J Appl Microbiol 119(2), 2015
PMID: 25963437
Jobbins SE, Alexander KA., J Wildl Dis 51(4), 2015
PMID: 26221860
Phylogenetic Distribution of CRISPR-Cas Systems in Antibiotic-Resistant Pseudomonas aeruginosa.
van Belkum A, Soriaga LB, LaFave MC, Akella S, Veyrieras JB, Barbu EM, Shortridge D, Blanc B, Hannum G, Zambardi G, Miller K, Enright MC, Mugnier N, Brami D, Schicklin S, Felderman M, Schwartz AS, Richardson TH, Peterson TC, Hubby B, Cady KC., MBio 6(6), 2015
PMID: 26604259
The broad-host-range plasmid pSFA231 isolated from petroleum-contaminated sediment represents a new member of the PromA plasmid family.
Li X, Top EM, Wang Y, Brown CJ, Yao F, Yang S, Jiang Y, Li H., Front Microbiol 5(), 2014
PMID: 25628616
Integrons: past, present, and future.
Gillings MR., Microbiol Mol Biol Rev 78(2), 2014
PMID: 24847022
An improved method for including upper size range plasmids in metamobilomes.
Norman A, Riber L, Luo W, Li LL, Hansen LH, Sørensen SJ., PLoS One 9(8), 2014
PMID: 25116381
IMP-1 encoded by a novel Tn402-like class 1 integron in clinical Achromobacter xylosoxidans, China.
Chen Z, Fang H, Wang L, Sun F, Wang Y, Yin Z, Yang H, Yang W, Wang J, Xia P, Zhou D, Liu C., Sci Rep 4(), 2014
PMID: 25428613
Shotgun metagenomics reveals a wide array of antibiotic resistance genes and mobile elements in a polluted lake in India.
Bengtsson-Palme J, Boulund F, Fick J, Kristiansson E, Larsson DG., Front Microbiol 5(), 2014
PMID: 25520706
Biodegradation potential of ofloxacin and its resulting transformation products during photolytic and photocatalytic treatment.
Vasquez MI, Hapeshi E, Fatta-Kassinos D, Kümmerer K., Environ Sci Pollut Res Int 20(3), 2013
PMID: 22855356
Inferring the evolutionary history of IncP-1 plasmids despite incongruence among backbone gene trees.
Sen D, Brown CJ, Top EM, Sullivan J., Mol Biol Evol 30(1), 2013
PMID: 22936717
Distribution and diversity of bacterial secretion systems across metagenomic datasets.
Barret M, Egan F, O'Gara F., Environ Microbiol Rep 5(1), 2013
PMID: 23757140
Ordering the bestiary of genetic elements transmissible by conjugation.
Garcillán-Barcia MP, de la Cruz F., Mob Genet Elements 3(1), 2013
PMID: 23734300
Widespread dissemination of class 1 integron components in soils and related ecosystems as revealed by cultivation-independent analysis.
Jechalke S, Schreiter S, Wolters B, Dealtry S, Heuer H, Smalla K., Front Microbiol 4(), 2013
PMID: 24478761
Detection and fate of antibiotic resistant bacteria in wastewater treatment plants: a review.
Bouki C, Venieri D, Diamadopoulos E., Ecotoxicol Environ Saf 91(), 2013
PMID: 23414720
Community-wide plasmid gene mobilization and selection.
Sentchilo V, Mayer AP, Guy L, Miyazaki R, Green Tringe S, Barry K, Malfatti S, Goessmann A, Robinson-Rechavi M, van der Meer JR., ISME J 7(6), 2013
PMID: 23407308
Antibiotic resistant Escherichia coli in hospital and municipal sewage and their emission to the environment.
Korzeniewska E, Korzeniewska A, Harnisz M., Ecotoxicol Environ Saf 91(), 2013
PMID: 23433837
Antibiotic resistance shaping multi-level population biology of bacteria.
Baquero F, Tedim AP, Coque TM., Front Microbiol 4(), 2013
PMID: 23508522
Broad-host-range IncP-1 plasmids and their resistance potential.
Popowska M, Krawczyk-Balska A., Front Microbiol 4(), 2013
PMID: 23471189
Human health implications of clinically relevant bacteria in wastewater habitats.
Varela AR, Manaia CM., Environ Sci Pollut Res Int 20(6), 2013
PMID: 23508533
The detection and sequencing of a broad-host-range conjugative IncP-1β plasmid in an epidemic strain of Mycobacterium abscessus subsp. bolletii.
Leão SC, Matsumoto CK, Carneiro A, Ramos RT, Nogueira CL, Lima JD, Lima KV, Lopes ML, Schneider H, Azevedo VA, da Costa da Silva A., PLoS One 8(4), 2013
PMID: 23565273
Comparative analysis and distribution of pP9014, a novel drug resistance IncP-1 plasmid from Photobacterium damselae subsp. piscicida.
del Castillo CS, Jang HB, Hikima J, Jung TS, Morii H, Hirono I, Kondo H, Kurosaka C, Aoki T., Int J Antimicrob Agents 42(1), 2013
PMID: 23602560
Management options for reducing the release of antibiotics and antibiotic resistance genes to the environment.
Pruden A, Larsson DG, Amézquita A, Collignon P, Brandt KK, Graham DW, Lazorchak JM, Suzuki S, Silley P, Snape JR, Topp E, Zhang T, Zhu YG., Environ Health Perspect 121(8), 2013
PMID: 23735422
Comparative genomics of IncP-1ε plasmids from water environments reveals diverse and unique accessory genetic elements.
Oliveira CS, Moura A, Henriques I, Brown CJ, Rogers LM, Top EM, Correia A., Plasmid 70(3), 2013
PMID: 23831558
High prevalence of IncP-1 plasmids and IS1071 insertion sequences in on-farm biopurification systems and other pesticide-polluted environments.
Dunon V, Sniegowski K, Bers K, Lavigne R, Smalla K, Springael D., FEMS Microbiol Ecol 86(3), 2013
PMID: 23802695
Horizontal transfer of antibiotic resistance genes in a membrane bioreactor.
Yang D, Wang J, Qiu Z, Jin M, Shen Z, Chen Z, Wang X, Zhang B, Li JW., J Biotechnol 167(4), 2013
PMID: 23942379
Host range diversification within the IncP-1 plasmid group.
Yano H, Rogers LM, Knox MG, Heuer H, Smalla K, Brown CJ, Top EM., Microbiology 159(pt 11), 2013
PMID: 24002747
Broad host range plasmids.
Jain A, Srivastava P., FEMS Microbiol Lett 348(2), 2013
PMID: 23980652
Diverse broad-host-range plasmids from freshwater carry few accessory genes.
Brown CJ, Sen D, Yano H, Bauer ML, Rogers LM, Van der Auwera GA, Top EM., Appl Environ Microbiol 79(24), 2013
PMID: 24096417
Antimicrobial resistance of integron-harboring Escherichia coli isolates from clinical samples, wastewater treatment plant and river water.
Koczura R, Mokracka J, Jabłońska L, Gozdecka E, Kubek M, Kaznowski A., Sci Total Environ 414(), 2012
PMID: 22119028
Risk assessment for ecotoxicity of pharmaceuticals--an emerging issue.
Kar S, Roy K., Expert Opin Drug Saf 11(2), 2012
PMID: 22166011
Quantification and characterization of β-lactam resistance genes in 15 sewage treatment plants from East Asia and North America.
Yang Y, Zhang T, Zhang XX, Liang DW, Zhang M, Gao DW, Zhu HG, Huang QG, Fang HH., Appl Microbiol Biotechnol 95(5), 2012
PMID: 22202968
Roles of long and short replication initiation proteins in the fate of IncP-1 plasmids.
Yano H, Deckert GE, Rogers LM, Top EM., J Bacteriol 194(6), 2012
PMID: 22228734
Plasmids foster diversification and adaptation of bacterial populations in soil.
Heuer H, Smalla K., FEMS Microbiol Rev 36(6), 2012
PMID: 22393901
Broad diversity of conjugative plasmids in integron-carrying bacteria from wastewater environments.
Moura A, Oliveira C, Henriques I, Smalla K, Correia A., FEMS Microbiol Lett 330(2), 2012
PMID: 22409355
Lateral genetic transfer and the construction of genetic exchange communities.
Skippington E, Ragan MA., FEMS Microbiol Rev 35(5), 2011
PMID: 21223321
The IncP-1 plasmid backbone adapts to different host bacterial species and evolves through homologous recombination.
Norberg P, Bergström M, Jethava V, Dubhashi D, Hermansson M., Nat Commun 2(), 2011
PMID: 21468020
Identification of bacterial plasmids based on mobility and plasmid population biology.
Garcillán-Barcia MP, Alvarado A, de la Cruz F., FEMS Microbiol Rev 35(5), 2011
PMID: 21711366
Molecular characterization of multidrug-resistant Escherichia coli isolates from Irish cattle farms.
Karczmarczyk M, Walsh C, Slowey R, Leonard N, Fanning S., Appl Environ Microbiol 77(20), 2011
PMID: 21856840
ArmA methyltransferase in a monophasic Salmonella enterica isolate from food.
Granier SA, Hidalgo L, San Millan A, Escudero JA, Gutierrez B, Brisabois A, Gonzalez-Zorn B., Antimicrob Agents Chemother 55(11), 2011
PMID: 21859937
Broad-host-range plasmids from agricultural soils have IncP-1 backbones with diverse accessory genes.
Sen D, Van der Auwera GA, Rogers LM, Thomas CM, Brown CJ, Top EM., Appl Environ Microbiol 77(22), 2011
PMID: 21948829
Accounting for mating pair formation in plasmid population dynamics.
Zhong X, Krol JE, Top EM, Krone SM., J Theor Biol 262(4), 2010
PMID: 19835890
Comparative genomics of pAKD4, the prototype IncP-1delta plasmid with a complete backbone.
Sen D, Yano H, Suzuki H, Król JE, Rogers L, Brown CJ, Top EM., Plasmid 63(2), 2010
PMID: 20018208
Structure, function, and evolution of the Thiomonas spp. genome.
Arsène-Ploetze F, Koechler S, Marchal M, Coppée JY, Chandler M, Bonnefoy V, Brochier-Armanet C, Barakat M, Barbe V, Battaglia-Brunet F, Bruneel O, Bryan CG, Cleiss-Arnold J, Cruveiller S, Erhardt M, Heinrich-Salmeron A, Hommais F, Joulian C, Krin E, Lieutaud A, Lièvremont D, Michel C, Muller D, Ortet P, Proux C, Siguier P, Roche D, Rouy Z, Salvignol G, Slyemi D, Talla E, Weiss S, Weissenbach J, Médigue C, Bertin PN., PLoS Genet 6(2), 2010
PMID: 20195515
Does the wide use of quaternary ammonium compounds enhance the selection and spread of antimicrobial resistance and thus threaten our health?
Hegstad K, Langsrud S, Lunestad BT, Scheie AA, Sunde M, Yazdankhah SP., Microb Drug Resist 16(2), 2010
PMID: 20370507
Shifts in the host range of a promiscuous plasmid through parallel evolution of its replication initiation protein.
Sota M, Yano H, Hughes JM, Daughdrill GW, Abdo Z, Forney LJ, Top EM., ISME J 4(12), 2010
PMID: 20520653
Molecular epidemiology of ampicillin resistance in Salmonella spp. and Escherichia coli from wastewater and clinical specimens.
Pignato S, Coniglio MA, Faro G, Lefevre M, Weill FX, Giammanco G., Foodborne Pathog Dis 7(8), 2010
PMID: 20367333
Characterization and transferability of class 1 integrons in commensal bacteria isolated from farm and nonfarm environments.
Yang H, Byelashov OA, Geornaras I, Goodridge LD, Nightingale KK, Belk KE, Smith GC, Sofos JN., Foodborne Pathog Dis 7(12), 2010
PMID: 20704511
Mangrove microniches determine the structural and functional diversity of enriched petroleum hydrocarbon-degrading consortia.
Gomes NC, Flocco CG, Costa R, Junca H, Vilchez R, Pieper DH, Krögerrecklenfort E, Paranhos R, Mendonça-Hagler LC, Smalla K., FEMS Microbiol Ecol 74(2), 2010
PMID: 20812953
Genomic islands: tools of bacterial horizontal gene transfer and evolution.
Juhas M, van der Meer JR, Gaillard M, Harding RM, Hood DW, Crook DW., FEMS Microbiol Rev 33(2), 2009
PMID: 19178566
Antibiotic resistance genes in water environment.
Zhang XX, Zhang T, Fang HH., Appl Microbiol Biotechnol 82(3), 2009
PMID: 19130050
Acetylation of fluoroquinolone antimicrobial agents by an Escherichia coli strain isolated from a municipal wastewater treatment plant.
Jung CM, Heinze TM, Strakosha R, Elkins CA, Sutherland JB., J Appl Microbiol 106(2), 2009
PMID: 19200322
Plasmids captured in C. metallidurans CH34: defining the PromA family of broad-host-range plasmids.
Van der Auwera GA, Król JE, Suzuki H, Foster B, Van Houdt R, Brown CJ, Mergeay M, Top EM., Antonie Van Leeuwenhoek 96(2), 2009
PMID: 19259779
Wastewater treatment contributes to selective increase of antibiotic resistance among Acinetobacter spp.
Zhang Y, Marrs CF, Simon C, Xi C., Sci Total Environ 407(12), 2009
PMID: 19321192
Antibiotics in the aquatic environment--a review--part II.
Kümmerer K., Chemosphere 75(4), 2009
PMID: 19178931
Lateral genetic transfer: open issues.
Ragan MA, Beiko RG., Philos Trans R Soc Lond B Biol Sci 364(1527), 2009
PMID: 19571244
Adaptive plasmid evolution results in host-range expansion of a broad-host-range plasmid.
De Gelder L, Williams JJ, Ponciano JM, Sota M, Top EM., Genetics 178(4), 2008
PMID: 18430943
Genetic diversity and composition of a plasmid metagenome from a wastewater treatment plant.
Schlüter A, Krause L, Szczepanowski R, Goesmann A, Pühler A., J Biotechnol 136(1-2), 2008
PMID: 18603322
Insight into the plasmid metagenome of wastewater treatment plant bacteria showing reduced susceptibility to antimicrobial drugs analysed by the 454-pyrosequencing technology.
Szczepanowski R, Bekel T, Goesmann A, Krause L, Krömeke H, Kaiser O, Eichler W, Pühler A, Schlüter A., J Biotechnol 136(1-2), 2008
PMID: 18586057
Piggery manure used for soil fertilization is a reservoir for transferable antibiotic resistance plasmids.
Binh CT, Heuer H, Kaupenjohann M, Smalla K., FEMS Microbiol Ecol 66(1), 2008
PMID: 18557938
Transformation of N-phenylpiperazine by mixed cultures from a municipal wastewater treatment plant.
Jung CM, Heinze TM, Deck J, Strakosha R, Sutherland JB., Appl Environ Microbiol 74(19), 2008
PMID: 18676696
Novel insertion sequence- and transposon-mediated genetic rearrangements in genomic island SGI1 of Salmonella enterica serovar Kentucky.
Doublet B, Praud K, Bertrand S, Collard JM, Weill FX, Cloeckaert A., Antimicrob Agents Chemother 52(10), 2008
PMID: 18676889
Host-specific factors determine the persistence of IncP-1 plasmids
Sota M, Top EM., World J Microbiol Biotechnol 24(9), 2008
PMID: IND44085307
Using Mahalanobis distance to compare genomic signatures between bacterial plasmids and chromosomes.
Suzuki H, Sota M, Brown CJ, Top EM., Nucleic Acids Res 36(22), 2008
PMID: 18953039
IncP-1-beta plasmid pGNB1 isolated from a bacterial community from a wastewater treatment plant mediates decolorization of triphenylmethane dyes.
Schlüter A, Krahn I, Kollin F, Bönemann G, Stiens M, Szczepanowski R, Schneiker S, Pühler A., Appl Environ Microbiol 73(20), 2007
PMID: 17675426

238 References

Daten bereitgestellt von Europe PubMed Central.

Spread and survival of promiscuous IncP-1 plasmids.
Adamczyk M, Jagura-Burdzy G., Acta Biochim. Pol. 50(2), 2003
PMID: 12833168
The kfrA gene is the first in a tricistronic operon required for survival of IncP-1 plasmid R751.
Adamczyk M, Dolowy P, Jonczyk M, Thomas CM, Jagura-Burdzy G., Microbiology (Reading, Engl.) 152(Pt 6), 2006
PMID: 16735726
Occurrence of drug-resistant bacteria in two European eel farms.
Alcaide E, Blasco MD, Esteve C., Appl. Environ. Microbiol. 71(6), 2005
PMID: 15933039
Impact of conjugal transfer on the stability of IncP-1 plasmid pKJK5 in bacterial populations.
Bahl MI, Hansen LH, Sorensen SJ., FEMS Microbiol. Lett. 266(2), 2006
PMID: 17132149
Chloramphenicol: a review.
Balbi HJ., Pediatr Rev 25(8), 2004
PMID: 15286274
Transfer and occurrence of large mercury resistance plasmids in river epilithon.
Bale MJ, Fry JC, Day MJ., Appl. Environ. Microbiol. 54(4), 1988
PMID: 16347617
Bacterial mercury resistance from atoms to ecosystems.
Barkay T, Miller SM, Summers AO., FEMS Microbiol. Rev. 27(2-3), 2003
PMID: 12829275
The Pfam protein families database.
Bateman A, Coin L, Durbin R, Finn RD, Hollich V, Griffiths-Jones S, Khanna A, Marshall M, Moxon S, Sonnhammer EL, Studholme DJ, Yeats C, Eddy SR., Nucleic Acids Res. 32(Database issue), 2004
PMID: 14681378

Natural selection, infectious transfer and the existence conditions for bacterial plasmids.
Bergstrom CT, Lipsitch M, Levin BR., Genetics 155(4), 2000
PMID: 10924453
Complete sequence of pSC101.
Bernardi A, Bernardi F., Nucleic Acids Res. 12(24), 1984
PMID: 6096829
The bacterial ParA-ParB partitioning proteins.
Bignell C, Thomas CM., J. Biotechnol. 91(1), 2001
PMID: 11522360
Effect of growth rate and incC mutation on symmetric plasmid distribution by the IncP-1 partitioning apparatus.
Bignell CR, Haines AS, Khare D, Thomas CM., Mol. Microbiol. 34(2), 1999
PMID: 10564465
Regulatory circuits for plasmid survival.
Bingle LE, Thomas CM., Curr. Opin. Microbiol. 4(2), 2001
PMID: 11282476
The evolution and role of macrolides in infectious diseases.
Blondeau JM., Expert Opin Pharmacother 3(8), 2002
PMID: 12150692
The macrolides.
Blondeau JM, DeCarolis E, Metzler KL, Hansen GT., Expert Opin Investig Drugs 11(2), 2002
PMID: 11829712
Genetic diversity among 3-chloroaniline- and aniline-degrading strains of the Comamonadaceae.
Boon N, Goris J, De Vos P, Verstraete W, Top EM., Appl. Environ. Microbiol. 67(3), 2001
PMID: 11229899
Complete nucleotide sequence of a 92-kilobase plasmid harboring the CTX-M-15 extended-spectrum beta-lactamase involved in an outbreak in long-term-care facilities in Toronto, Canada.
Boyd DA, Tyler S, Christianson S, McGeer A, Muller MP, Willey BM, Bryce E, Gardam M, Nordmann P, Mulvey MR., Antimicrob. Agents Chemother. 48(10), 2004
PMID: 15388431
A physical and genetic map of the IncN plasmid R46.
Brown AM, Willetts NS., Plasmid 5(2), 1981
PMID: 6264522
The complete genome sequence of the Arabidopsis and tomato pathogen Pseudomonas syringae pv. tomato DC3000.
Buell CR, Joardar V, Lindeberg M, Selengut J, Paulsen IT, Gwinn ML, Dodson RJ, Deboy RT, Durkin AS, Kolonay JF, Madupu R, Daugherty S, Brinkac L, Beanan MJ, Haft DH, Nelson WC, Davidsen T, Zafar N, Zhou L, Liu J, Yuan Q, Khouri H, Fedorova N, Tran B, Russell D, Berry K, Utterback T, Van Aken SE, Feldblyum TV, D'Ascenzo M, Deng WL, Ramos AR, Alfano JR, Cartinhour S, Chatterjee AK, Delaney TP, Lazarowitz SG, Martin GB, Schneider DJ, Tang X, Bender CL, White O, Fraser CM, Collmer A., Proc. Natl. Acad. Sci. U.S.A. 100(18), 2003
PMID: 12928499
Veterinary use of antimicrobials and emergence of resistance in zoonotic and sentinel bacteria in the EU.
Bywater RJ., J. Vet. Med. B Infect. Dis. Vet. Public Health 51(8-9), 2004
PMID: 15525366
The versatile bacterial type IV secretion systems.
Cascales E, Christie PJ., Nat. Rev. Microbiol. 1(2), 2003
PMID: 15035043
Plasmid chromate resistance and chromate reduction.
Cervantes C, Silver S., Plasmid 27(1), 1992
PMID: 1741461
Interactions of chromium with microorganisms and plants.
Cervantes C, Campos-Garcia J, Devars S, Gutierrez-Corona F, Loza-Tavera H, Torres-Guzman JC, Moreno-Sanchez R., FEMS Microbiol. Rev. 25(3), 2001
PMID: 11348688
Open-label randomized trial of oral trimethoprim-sulfamethoxazole, doxycycline, and chloramphenicol compared with trimethoprim-sulfamethoxazole and doxycycline for maintenance therapy of melioidosis.
Chaowagul W, Chierakul W, Simpson AJ, Short JM, Stepniewska K, Maharjan B, Rajchanuvong A, Busarawong D, Limmathurotsakul D, Cheng AC, Wuthiekanun V, Newton PN, White NJ, Day NP, Peacock SJ., Antimicrob. Agents Chemother. 49(10), 2005
PMID: 16189075
The genome sequence of Salmonella enterica serovar Choleraesuis, a highly invasive and resistant zoonotic pathogen.
Chiu CH, Tang P, Chu C, Hu S, Bao Q, Yu J, Chou YY, Wang HS, Lee YS., Nucleic Acids Res. 33(5), 2005
PMID: 15781495
Type IV secretion: the Agrobacterium VirB/D4 and related conjugation systems.
Christie PJ., Biochim. Biophys. Acta 1694(1-3), 2004
PMID: 15546668
Structural and dynamic properties of bacterial type IV secretion systems (review).
Christie PJ, Cascales E., Mol. Membr. Biol. 22(1-2), 2005
PMID: 16092524
Biogenesis, architecture, and function of bacterial type IV secretion systems.
Christie PJ, Atmakuri K, Krishnamoorthy V, Jakubowski S, Cascales E., Annu. Rev. Microbiol. 59(), 2005
PMID: 16153176
Phylogeny of LCR-1 and OXA-5 with class A and class D beta-lactamases.
Couture F, Lachapelle J, Levesque RC., Mol. Microbiol. 6(12), 1992
PMID: 1495394

Properties of an R factor from Pseudomonas aeruginosa.
Datta N, Hedges RW, Shaw EJ, Sykes RB, Richmond MH., J. Bacteriol. 108(3), 1971
PMID: 4945193
Bacterial resistance to aminoglycoside antibiotics.
Davies J, Wright GD., Trends Microbiol. 5(6), 1997
PMID: 9211644
Linkage of a novel mercury resistance operon with streptomycin resistance on a conjugative plasmid in Enterococcus faecium.
Davis IJ, Roberts AP, Ready D, Richards H, Wilson M, Mullany P., Plasmid 54(1), 2004
PMID: 15907536
Genetic exchange between bacteria in the environment.
Davison J., Plasmid 42(2), 1999
PMID: 10489325
Stability of a promiscuous plasmid in different hosts: no guarantee for a long-term relationship.
De Gelder L, Ponciano JM, Joyce P, Top EM., Microbiology (Reading, Engl.) 153(Pt 2), 2007
PMID: 17259616


Tetracycline resistance in Chlamydia suis mediated by genomic islands inserted into the chlamydial inv-like gene.
Dugan J, Rockey DD, Jones L, Andersen AA., Antimicrob. Agents Chemother. 48(10), 2004
PMID: 15388463
Comparison of the complete genome sequences of Pseudomonas syringae pv. syringae B728a and pv. tomato DC3000.
Feil H, Feil WS, Chain P, Larimer F, DiBartolo G, Copeland A, Lykidis A, Trong S, Nolan M, Goltsman E, Thiel J, Malfatti S, Loper JE, Lapidus A, Detter JC, Land M, Richardson PM, Kyrpides NC, Ivanova N, Lindow SE., Proc. Natl. Acad. Sci. U.S.A. 102(31), 2005
PMID: 16043691
Antibiotic resistance: a view from the prescriber.
Finch RG., Nat. Rev. Microbiol. 2(12), 2004
PMID: 15550945
Bacterial resistance to beta-lactam antibiotics: compelling opportunism, compelling opportunity.
Fisher JF, Meroueh SO, Mobashery S., Chem. Rev. 105(2), 2005
PMID: 15700950
Resistance integrons and super-integrons.
Fluit AC, Schmitz FJ., Clin. Microbiol. Infect. 10(4), 2004
PMID: 15059115
Mobile genetic elements: the agents of open source evolution.
Frost LS, Leplae R, Summers AO, Toussaint A., Nat. Rev. Microbiol. 3(9), 2005
PMID: 16138100


Incidence of class 1 integrons in a quaternary ammonium compound-polluted environment.
Gaze WH, Abdouslam N, Hawkey PM, Wellington EM., Antimicrob. Agents Chemother. 49(5), 2005
PMID: 15855499
Recombinant DNA plasmid transmission to indigenous organisms during wastewater treatment
Gealt, 1988
Coupling factors in macromolecular type-IV secretion machineries.
Gomis-Ruth FX, Sola M, de la Cruz F, Coll M., Curr. Pharm. Des. 10(13), 2004
PMID: 15134575
Structural, molecular, and genetic analysis of the kilA operon of broad-host-range plasmid RK2.
Goncharoff P, Saadi S, Chang CH, Saltman LH, Figurski DH., J. Bacteriol. 173(11), 1991
PMID: 2045366
European status of resistance in nosocomial infections.
Goossens H., Chemotherapy 51(4), 2005
PMID: 16006764
Replication functions of new broad host range plasmids isolated from polluted soils.
Gstalder ME, Faelen M, Mine N, Top EM, Mergeay M, Couturier M., Res. Microbiol. 154(7), 2003
PMID: 14499936
Transferable plasmid-mediated resistance to streptomycin in a clinical isolate of Yersinia pestis.
Guiyoule A, Gerbaud G, Buchrieser C, Galimand M, Rahalison L, Chanteau S, Courvalin P, Carniel E., Emerging Infect. Dis. 7(1), 2001
PMID: 11266293
Plasmids from freshwater environments capable of IncQ retrotransfer are diverse and include pQKH54, a new IncP-1 subgroup archetype.
Haines AS, Akhtar P, Stephens ER, Jones K, Thomas CM, Perkins CD, Williams JR, Day MJ, Fry JC., Microbiology (Reading, Engl.) 152(Pt 9), 2006
PMID: 16946264
Sequence of plasmid pBS228 and reconstruction of the IncP-1alpha phylogeny.
Haines AS, Jones K, Batt SM, Kosheleva IA, Thomas CM., Plasmid 58(1), 2007
PMID: 17320955
High rates of conjugation in bacterial biofilms as determined by quantitative in situ analysis.
Hausner M, Wuertz S., Appl. Environ. Microbiol. 65(8), 1999
PMID: 10427070
Bacterial conjugative plasmids mobilize DNA transfer between bacteria and yeast.
Heinemann JA, Sprague GF Jr., Nature 340(6230), 1989
PMID: 2666856
Beta-lactamases: a survey of protein diversity.
Helfand MS, Bonomo RA., Curr Drug Targets Infect Disord 3(1), 2003
PMID: 12570729
Gentamicin resistance genes in environmental bacteria: prevalence and transfer.
Heuer H, Krogerrecklenfort E, Wellington EM, Egan S, van Elsas JD, van Overbeek L, Collard JM, Guillaume G, Karagouni AD, Nikolakopoulou TL, Smalla K., FEMS Microbiol. Ecol. 42(2), 2002
PMID: 19709289
The complete sequences of plasmids pB2 and pB3 provide evidence for a recent ancestor of the IncP-1beta group without any accessory genes.
Heuer H, Szczepanowski R, Schneiker S, Puhler A, Top EM, Schluter A., Microbiology (Reading, Engl.) 150(Pt 11), 2004
PMID: 15528648
Isolation and screening of plasmids from the epilithon which mobilize recombinant plasmid pD10.
Hill KE, Weightman AJ, Fry JC., Appl. Environ. Microbiol. 58(4), 1992
PMID: 1599248

Resistance to trimethoprim-sulfamethoxazole.
Huovinen P., Clin. Infect. Dis. 32(11), 2001
PMID: 11340533
Trimethoprim and sulfonamide resistance.
Huovinen P, Sundstrom L, Swedberg G, Skold O., Antimicrob. Agents Chemother. 39(2), 1995
PMID: 7726483

ParE toxin encoded by the broad-host-range plasmid RK2 is an inhibitor of Escherichia coli gyrase.
Jiang Y, Pogliano J, Helinski DR, Konieczny I., Mol. Microbiol. 44(4), 2002
PMID: 12010492
Trimethoprim R factors in enterobacteria from clinical specimens.
Jobanputra RS, Datta N., J. Med. Microbiol. 7(2), 1974
PMID: 4599661
Molecular basis of resistance to trimethoprim, chloramphenicol and sulphonamides in Bordetella bronchiseptica.
Kadlec K, Kehrenberg C, Schwarz S., J. Antimicrob. Chemother. 56(3), 2005
PMID: 16046466
Tying rings for sex.
Kalkum M, Eisenbrandt R, Lurz R, Lanka E., Trends Microbiol. 10(8), 2002
PMID: 12160637
Protein circlets as sex pilus subunits.
Kalkum M, Eisenbrandt R, Lanka E., Curr. Protein Pept. Sci. 5(5), 2004
PMID: 15544536
Plasmid pBP136 from Bordetella pertussis represents an ancestral form of IncP-1beta plasmids without accessory mobile elements.
Kamachi K, Sota M, Tamai Y, Nagata N, Konda T, Inoue T, Top EM, Arakawa Y., Microbiology (Reading, Engl.) 152(Pt 12), 2006
PMID: 17159199
Transposon targeting determined by resolvase.
Kamali-Moghaddam M, Sundstrom L., FEMS Microbiol. Lett. 186(1), 2000
PMID: 10779712
Distribution of the antiseptic-resistance gene qacE delta 1 in gram-positive bacteria.
Kazama H, Hamashima H, Sasatsu M, Arai T., FEMS Microbiol. Lett. 165(2), 1998
PMID: 9742702
Distribution of the antiseptic-resistance genes qacE and qacE delta 1 in gram-negative bacteria.
Kazama H, Hamashima H, Sasatsu M, Arai T., FEMS Microbiol. Lett. 159(2), 1998
PMID: 9503610
Aminoglycosides: perspectives on mechanisms of action and resistance and strategies to counter resistance.
Kotra LP, Haddad J, Mobashery S., Antimicrob. Agents Chemother. 44(12), 2000
PMID: 11083623

Significance of antibiotics in the environment.
Kummerer K., J. Antimicrob. Chemother. 52(1), 2003
PMID: 12805262
A global non-conjugative Tet C plasmid, pRAS3, from Aeromonas salmonicida.
L'Abee-Lund TM, Sorum H., Plasmid 47(3), 2002
PMID: 12151232
Diversity of TEM-52 extended-spectrum beta-lactamase-producing non-typhoidal Salmonella isolates in Korea.
Lee K, Yong D, Yum JH, Kim HH, Chong Y., J. Antimicrob. Chemother. 52(3), 2003
PMID: 12917235
Emergence of multidrug-resistant Salmonella enterica serovar typhi in Korea.
Lee K, Yong D, Yum JH, Lim YS, Kim HS, Lee BK, Chong Y., Antimicrob. Agents Chemother. 48(11), 2004
PMID: 15504831


R-plasmid transfer in a wastewater treatment plant.
Mach PA, Grimes DJ., Appl. Environ. Microbiol. 44(6), 1982
PMID: 6760813
Mobilization of plasmid pHSV106 from Escherichia coli HB101 in a laboratory-scale waste treatment facility.
Mancini P, Fertels S, Nave D, Gealt MA., Appl. Environ. Microbiol. 53(4), 1987
PMID: 3555335
Complete nucleotide sequence and organization of the atrazine catabolic plasmid pADP-1 from Pseudomonas sp. strain ADP.
Martinez B, Tomkins J, Wackett LP, Wing R, Sadowsky MJ., J. Bacteriol. 183(19), 2001
PMID: 11544232
Integrons: agents of bacterial evolution.
Mazel D., Nat. Rev. Microbiol. 4(8), 2006
PMID: 16845431
Antibiotic resistance in microbes.
Mazel D, Davies J., Cell. Mol. Life Sci. 56(9-10), 1999
PMID: 11212334
Intergeneric conjugation between Escherichia coli and Streptomyces species.
Mazodier P, Petter R, Thompson C., J. Bacteriol. 171(6), 1989
PMID: 2656662
Antiseptics and disinfectants: activity, action, and resistance.
McDonnell G, Russell AD., Clin. Microbiol. Rev. 12(1), 1999
PMID: 9880479
Antibiotic use in plant agriculture.
McManus PS, Stockwell VO, Sundin GW, Jones AL., Annu Rev Phytopathol 40(), 2002
PMID: 12147767
Isolation of indigenous wastewater bacterial strains capable of mobilizing plasmid pBR325.
McPherson P, Gealt MA., Appl. Environ. Microbiol. 51(5), 1986
PMID: 3524455
Ralstonia metallidurans, a bacterium specifically adapted to toxic metals: towards a catalogue of metal-responsive genes.
Mergeay M, Monchy S, Vallaeys T, Auquier V, Benotmane A, Bertin P, Taghavi S, Dunn J, van der Lelie D, Wattiez R., FEMS Microbiol. Rev. 27(2-3), 2003
PMID: 12829276
Mercury resistance transposons of gram-negative environmental bacteria and their classification.
Mindlin S, Kholodii G, Gorlenko Z, Minakhina S, Minakhin L, Kalyaeva E, Kopteva A, Petrova M, Yurieva O, Nikiforov V., Res. Microbiol. 152(9), 2001
PMID: 11763242
Aminoglycosides: activity and resistance.
Mingeot-Leclercq MP, Glupczynski Y, Tulkens PM., Antimicrob. Agents Chemother. 43(4), 1999
PMID: 10103173
OXA-type beta-lactamases.
Naas T, Nordmann P., Curr. Pharm. Des. 5(11), 1999
PMID: 10539993
Complete genome sequence and comparative analysis of the metabolically versatile Pseudomonas putida KT2440.
Nelson KE, Weinel C, Paulsen IT, Dodson RJ, Hilbert H, Martins dos Santos VA, Fouts DE, Gill SR, Pop M, Holmes M, Brinkac L, Beanan M, DeBoy RT, Daugherty S, Kolonay J, Madupu R, Nelson W, White O, Peterson J, Khouri H, Hance I, Chris Lee P, Holtzapple E, Scanlan D, Tran K, Moazzez A, Utterback T, Rizzo M, Lee K, Kosack D, Moestl D, Wedler H, Lauber J, Stjepandic D, Hoheisel J, Straetz M, Heim S, Kiewitz C, Eisen JA, Timmis KN, Dusterhoft A, Tummler B, Fraser CM., Environ. Microbiol. 4(12), 2002
PMID: 12534463
Efflux-mediated heavy metal resistance in prokaryotes.
Nies DH., FEMS Microbiol. Rev. 27(2-3), 2003
PMID: 12829273
Isolation and characterization of naphthalene-catabolic genes and plasmids from oil-contaminated soil by using two cultivation-independent approaches.
Ono A, Miyazaki R, Sota M, Ohtsubo Y, Nagata Y, Tsuda M., Appl. Microbiol. Biotechnol. 74(2), 2006
PMID: 17096121
Distribution, diversity and evolution of the bacterial mercury resistance (mer) operon.
Osborn AM, Bruce KD, Strike P, Ritchie DA., FEMS Microbiol. Rev. 19(4), 1997
PMID: 9167257
Sequences of the NPS-1 and TLE-1 beta-lactamase genes.
Pai H, Jacoby GA., Antimicrob. Agents Chemother. 45(10), 2001
PMID: 11557499

Complete nucleotide sequence of Birmingham IncP alpha plasmids. Compilation and comparative analysis.
Pansegrau W, Lanka E, Barth PT, Figurski DH, Guiney DG, Haas D, Helinski DR, Schwab H, Stanisich VA, Thomas CM., J. Mol. Biol. 239(5), 1994
PMID: 8014987
Complete genome sequence of a multiple drug resistant Salmonella enterica serovar Typhi CT18.
Parkhill J, Dougan G, James KD, Thomson NR, Pickard D, Wain J, Churcher C, Mungall KL, Bentley SD, Holden MT, Sebaihia M, Baker S, Basham D, Brooks K, Chillingworth T, Connerton P, Cronin A, Davis P, Davies RM, Dowd L, White N, Farrar J, Feltwell T, Hamlin N, Haque A, Hien TT, Holroyd S, Jagels K, Krogh A, Larsen TS, Leather S, Moule S, O'Gaora P, Parry C, Quail M, Rutherford K, Simmonds M, Skelton J, Stevens K, Whitehead S, Barrell BG., Nature 413(6858), 2001
PMID: 11677608
In34, a complex In5 family class 1 integron containing orf513 and dfrA10.
Partridge SR, Hall RM., Antimicrob. Agents Chemother. 47(1), 2003
PMID: 12499211
Characterization and movement of the class 1 integron known as Tn2521 and Tn1405.
Partridge SR, Brown HJ, Hall RM., Antimicrob. Agents Chemother. 46(5), 2002
PMID: 11959558
Physical linkage of Tn3 and part of Tn1721 in a tetracycline and ampicillin resistance plasmid from Salmonella Typhimurium.
Pasquali F, Kehrenberg C, Manfreda G, Schwarz S., J. Antimicrob. Chemother. 55(4), 2005
PMID: 15731203
The 3' conserved segment of integrons contains a gene associated with multidrug resistance to antiseptics and disinfectants.
Paulsen IT, Littlejohn TG, Radstrom P, Sundstrom L, Skold O, Swedberg G, Skurray RA., Antimicrob. Agents Chemother. 37(4), 1993
PMID: 8494372
Complete genome sequence of the plant commensal Pseudomonas fluorescens Pf-5.
Paulsen IT, Press CM, Ravel J, Kobayashi DY, Myers GS, Mavrodi DV, DeBoy RT, Seshadri R, Ren Q, Madupu R, Dodson RJ, Durkin AS, Brinkac LM, Daugherty SC, Sullivan SA, Rosovitz MJ, Gwinn ML, Zhou L, Schneider DJ, Cartinhour SW, Nelson WC, Weidman J, Watkins K, Tran K, Khouri H, Pierson EA, Pierson LS 3rd, Thomashow LS, Loper JE., Nat. Biotechnol. 23(7), 2005
PMID: 15980861
Insertion sequence ISEcp1B is involved in expression and mobilization of a bla(CTX-M) beta-lactamase gene.
Poirel L, Decousser JW, Nordmann P., Antimicrob. Agents Chemother. 47(9), 2003
PMID: 12936998

Resistance to beta-lactam antibiotics.
Poole K., Cell. Mol. Life Sci. 61(17), 2004
PMID: 15338052
Efflux-mediated multiresistance in Gram-negative bacteria.
Poole K., Clin. Microbiol. Infect. 10(1), 2004
PMID: 14706082
Efflux-mediated antimicrobial resistance.
Poole K., J. Antimicrob. Chemother. 56(1), 2005
PMID: 15914491
Synergistic effects in mixed Escherichia coli biofilms: conjugative plasmid transfer drives biofilm expansion.
Reisner A, Holler BM, Molin S, Zechner EL., J. Bacteriol. 188(10), 2006
PMID: 16672612
Two aberrant mercury resistance transposons in the Pseudomonas stutzeri plasmid pPB.
Reniero D, Mozzon E, Galli E, Barbieri P., Gene 208(1), 1998
PMID: 9479042
Complete nucleotide sequence of the conjugative tetracycline resistance plasmid pFBAOT6, a member of a group of IncU plasmids with global ubiquity.
Rhodes G, Parkhill J, Bird C, Ambrose K, Jones MC, Huys G, Swings J, Pickup RW., Appl. Environ. Microbiol. 70(12), 2004
PMID: 15574953
Partial characterization of a transposon containing the tet(A) determinant in a clinical isolate of Acinetobacter baumannii.
Ribera A, Roca I, Ruiz J, Gibert I, Vila J., J. Antimicrob. Chemother. 52(3), 2003
PMID: 12888597
Update on acquired tetracycline resistance genes.
Roberts MC., FEMS Microbiol. Lett. 245(2), 2005
PMID: 15837373
The role of integrons in antibiotic resistance gene capture.
Rowe-Magnus DA, Mazel D., Int. J. Med. Microbiol. 292(2), 2002
PMID: 12195734
Resistance to antimicrobial agents: an update.
Rybak MJ., Pharmacotherapy 24(12 Pt 2), 2004
PMID: 15585450
Molecular basis of bacterial resistance to chloramphenicol and florfenicol.
Schwarz S, Kehrenberg C, Doublet B, Cloeckaert A., FEMS Microbiol. Rev. 28(5), 2004
PMID: 15539072

Antibiotic resistance: a survival strategy.
Sheldon AT Jr., Clin Lab Sci 18(3), 2005
PMID: 16134477
The genome sequence of the plant pathogen Xylella fastidiosa. The Xylella fastidiosa Consortium of the Organization for Nucleotide Sequencing and Analysis.
Simpson AJ, Reinach FC, Arruda P, Abreu FA, Acencio M, Alvarenga R, Alves LM, Araya JE, Baia GS, Baptista CS, Barros MH, Bonaccorsi ED, Bordin S, Bove JM, Briones MR, Bueno MR, Camargo AA, Camargo LE, Carraro DM, Carrer H, Colauto NB, Colombo C, Costa FF, Costa MC, Costa-Neto CM, Coutinho LL, Cristofani M, Dias-Neto E, Docena C, El-Dorry H, Facincani AP, Ferreira AJ, Ferreira VC, Ferro JA, Fraga JS, Franca SC, Franco MC, Frohme M, Furlan LR, Garnier M, Goldman GH, Goldman MH, Gomes SL, Gruber A, Ho PL, Hoheisel JD, Junqueira ML, Kemper EL, Kitajima JP, Krieger JE, Kuramae EE, Laigret F, Lambais MR, Leite LC, Lemos EG, Lemos MV, Lopes SA, Lopes CR, Machado JA, Machado MA, Madeira AM, Madeira HM, Marino CL, Marques MV, Martins EA, Martins EM, Matsukuma AY, Menck CF, Miracca EC, Miyaki CY, Monteriro-Vitorello CB, Moon DH, Nagai MA, Nascimento AL, Netto LE, Nhani A Jr, Nobrega FG, Nunes LR, Oliveira MA, de Oliveira MC, de Oliveira RC, Palmieri DA, Paris A, Peixoto BR, Pereira GA, Pereira HA Jr, Pesquero JB, Quaggio RB, Roberto PG, Rodrigues V, de M Rosa AJ, de Rosa VE Jr, de Sa RG, Santelli RV, Sawasaki HE, da Silva AC, da Silva AM, da Silva FR, da Silva WA Jr, da Silveira JF, Silvestri ML, Siqueira WJ, de Souza AA, de Souza AP, Terenzi MF, Truffi D, Tsai SM, Tsuhako MH, Vallada H, Van Sluys MA, Verjovski-Almeida S, Vettore AL, Zago MA, Zatz M, Meidanis J, Setubal JC., Nature 406(6792), 2000
PMID: 10910347
Resistance to trimethoprim and sulfonamides.
Skold O., Vet. Res. 32(3-4), 2001
PMID: 11432417


Isolation of broad-host-range replicons from marine sediment bacteria.
Sobecky PA, Mincer TJ, Chang MC, Toukdarian A, Helinski DR., Appl. Environ. Microbiol. 64(8), 1998
PMID: 9687436
Integron-containing IncU R plasmids pRAS1 and pAr-32 from the fish pathogen Aeromonas salmonicida.
Sorum H, L'Abee-Lund TM, Solberg A, Wold A., Antimicrob. Agents Chemother. 47(4), 2003
PMID: 12654659
Class 1 integrons potentially predating the association with tn402-like transposition genes are present in a sediment microbial community.
Stokes HW, Nesbo CL, Holley M, Bahl MI, Gillings MR, Boucher Y., J. Bacteriol. 188(16), 2006
PMID: 16885440
Mercury released from dental "silver" fillings provokes an increase in mercury- and antibiotic-resistant bacteria in oral and intestinal floras of primates.
Summers AO, Wireman J, Vimy MJ, Lorscheider FL, Marshall B, Levy SB, Bennett S, Billard L., Antimicrob. Agents Chemother. 37(4), 1993
PMID: 8280208
Multicopy plasmid instability: the dimer catastrophe hypothesis.
Summers DK, Beton CW, Withers HL., Mol. Microbiol. 8(6), 1993
PMID: 8361350
Complete nucleotide sequence and analysis of pPSR1 (72,601 bp), a pPT23A-family plasmid from Pseudomonas syringae pv. syringae A2.
Sundin GW, Mayfield CT, Zhao Y, Gunasekera TS, Foster GL, Ullrich MS., Mol. Genet. Genomics 270(6), 2003
PMID: 14634868
Novel macrolide resistance module carried by the IncP-1beta resistance plasmid pRSB111, isolated from a wastewater treatment plant.
Szczepanowski R, Krahn I, Bohn N, Puhler A, Schluter A., Antimicrob. Agents Chemother. 51(2), 2006
PMID: 17101677
Retrotransfer or gene capture: a feature of conjugative plasmids, with ecological and evolutionary significance.
Szpirer C, Top E, Couturier M, Mergeay M., Microbiology (Reading, Engl.) 145 ( Pt 12)(), 1999
PMID: 10627031
The COG database: new developments in phylogenetic classification of proteins from complete genomes.
Tatusov RL, Natale DA, Garkavtsev IV, Tatusova TA, Shankavaram UT, Rao BS, Kiryutin B, Galperin MY, Fedorova ND, Koonin EV., Nucleic Acids Res. 29(1), 2001
PMID: 11125040
The complete nucleotide sequence and environmental distribution of the cryptic, conjugative, broad-host-range plasmid pIPO2 isolated from bacteria of the wheat rhizosphere.
Tauch A, Schneiker S, Selbitschka W, Puhler A, van Overbeek LS, Smalla K, Thomas CM, Bailey MJ, Forney LJ, Weightman A, Ceglowski P, Pembroke T, Tietze E, Schroder G, Lanka E, van Elsas JD., Microbiology (Reading, Engl.) 148(Pt 6), 2002
PMID: 12055285

Occurrence of integron-associated resistance gene cassettes located on antibiotic resistance plasmids isolated from a wastewater treatment plant.
Tennstedt T, Szczepanowski R, Braun S, Puhler A, Schluter A., FEMS Microbiol. Ecol. 45(3), 2003
PMID: 19719593
N conjugative transfer system of plasmid pCU1.
Thatte V, Bradley DE, Iyer VN., J. Bacteriol. 163(3), 1985
PMID: 2863255
Molecular genetics of broad host range plasmid RK2.
Thomas CM., Plasmid 5(1), 1981
PMID: 6164066
Paradigms of plasmid organization.
Thomas CM., Mol. Microbiol. 37(3), 2000
PMID: 10931342

Transcription regulatory circuits in bacterial plasmids.
Thomas CM., Biochem. Soc. Trans. 34(Pt 6), 2006
PMID: 17073753
Mechanisms of, and barriers to, horizontal gene transfer between bacteria.
Thomas CM, Nielsen KM., Nat. Rev. Microbiol. 3(9), 2005
PMID: 16138099
Incompatibility group P plasmids: genetics, evolution, and use in genetic manipulation.
Thomas CM, Smith CA., Annu. Rev. Microbiol. 41(), 1987
PMID: 3318684
Complete sequence of the IncPbeta plasmid R751: implications for evolution and organisation of the IncP backbone.
Thorsted PB, Macartney DP, Akhtar P, Haines AS, Ali N, Davidson P, Stafford T, Pocklington MJ, Pansegrau W, Wilkins BM, Lanka E, Thomas CM., J. Mol. Biol. 282(5), 1998
PMID: 9753548
Exogenous isolation of mobilizing plasmids from polluted soils and sludges.
Top E, De Smet I, Verstraete W, Dijkmans R, Mergeay M., Appl. Environ. Microbiol. 60(3), 1994
PMID: 16349216
The role of mobile genetic elements in bacterial adaptation to xenobiotic organic compounds.
Top EM, Springael D., Curr. Opin. Biotechnol. 14(3), 2003
PMID: 12849778
First detection of a carbapenem-hydrolyzing metalloenzyme in two enterobacteriaceae isolates in Spain.
Tortola MT, Lavilla S, Miro E, Gonzalez JJ, Larrosa N, Sabate M, Navarro F, Prats G., Antimicrob. Agents Chemother. 49(8), 2005
PMID: 16048967
Mobile elements as a combination of functional modules.
Toussaint A, Merlin C., Plasmid 47(1), 2002
PMID: 11798283
Genetic organization of the catabolic plasmid pJP4 from Ralstonia eutropha JMP134 (pJP4) reveals mechanisms of adaptation to chloroaromatic pollutants and evolution of specialized chloroaromatic degradation pathways.
Trefault N, De la Iglesia R, Molina AM, Manzano M, Ledger T, Perez-Pantoja D, Sanchez MA, Stuardo M, Gonzalez B., Environ. Microbiol. 6(7), 2004
PMID: 15186344
Isolation, characterization, and transfer of cryptic gene-mobilizing plasmids in the wheat rhizosphere.
van Elsas JD, Gardener BB, Wolters AC, Smit E., Appl. Environ. Microbiol. 64(3), 1998
PMID: 9501428
Prevalence of streptomycin-resistance genes in bacterial populations in European habitats.
van Overbeek LS, Wellington EM, Egan S, Smalla K, Heuer H, Collard JM, Guillaume G, Karagouni AD, Nikolakopoulou TL, van Elsas JD., FEMS Microbiol. Ecol. 42(2), 2002
PMID: 19709288
Complete DNA sequence and analysis of the large virulence plasmid of Shigella flexneri.
Venkatesan MM, Goldberg MB, Rose DJ, Grotbeck EJ, Burland V, Blattner FR., Infect. Immun. 69(5), 2001
PMID: 11292750
Emergence of DHA-1-producing Klebsiella spp. in the Parisian region: genetic organization of the ampC and ampR genes originating from Morganella morganii.
Verdet C, Benzerara Y, Gautier V, Adam O, Ould-Hocine Z, Arlet G., Antimicrob. Agents Chemother. 50(2), 2006
PMID: 16436717
Multidrug and broad-spectrum cephalosporin resistance among Salmonella enterica serotype enteritidis clinical isolates in southern Italy.
Villa L, Mammina C, Miriagou V, Tzouvelekis LS, Tassios PT, Nastasi A, Carattoli A., J. Clin. Microbiol. 40(7), 2002
PMID: 12089302

Integrons and beta-lactamases--a novel perspective on resistance.
Weldhagen GF., Int. J. Antimicrob. Agents 23(6), 2004
PMID: 15194125
Active partitioning of bacterial plasmids.
Williams DR, Thomas CM., J. Gen. Microbiol. 138(1), 1992
PMID: 1556544
Trimethoprim/sulfamethoxazole resistance in clinical isolates of Burkholderia pseudomallei.
Wuthiekanun V, Cheng AC, Chierakul W, Amornchai P, Limmathurotsakul D, Chaowagul W, Simpson AJ, Short JM, Wongsuvan G, Maharjan B, White NJ, Peacock SJ., J. Antimicrob. Chemother. 55(6), 2005
PMID: 15886263
Cooperativity between KorB and TrbA repressors of broad-host-range plasmid RK2.
Zatyka M, Bingle L, Jones AC, Thomas CM., J. Bacteriol. 183(3), 2001
PMID: 11208801
Mechanisms of plasmid stable maintenance with special focus on plasmid addiction systems.
Zielenkiewicz U, Ceglowski P., Acta Biochim. Pol. 48(4), 2001
PMID: 11995964

Markieren/ Markierung löschen
Markierte Publikationen

Open Data PUB

Web of Science

Dieser Datensatz im Web of Science®

PMID: 17553065
PubMed | Europe PMC

Suchen in

Google Scholar