Rapid discovery of terpene tailoring enzymes for total biosynthesis
Sun Y, Gerke J, Becker K, Kuhnert E, Verwaaijen B, Wibberg D, Kalinowski J, Stadler M, Cox RJ (2023)
Chemical Science 14(46): 13463-13467.
Zeitschriftenaufsatz
| Veröffentlicht | Englisch
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Autor*in
Sun, Yunlong;
Gerke, Jennifer;
Becker, Kevin;
Kuhnert, Eric;
Verwaaijen, BartUniBi;
Wibberg, DanielUniBi;
Kalinowski, JörnUniBi;
Stadler, Marc;
Cox, Russell J.
Einrichtung
Abstract / Bemerkung
Twenty oxygenated aristolochene congeners were rapidly synthesised by combining genes from four different fungal pathways in the fungal host organism Aspergillus oryzae. Compounds produced in a single step include the natural product hypoxylan A and an epimer of guignaderemophilane C. A new fungal aromatase was discovered that produces phenols by oxidative demethylation. Twenty oxygenated aristolochene congeners were rapidly synthesised by combining genes from four different fungal pathways in the fungal host organism Aspergillus oryzae.
Erscheinungsjahr
2023
Zeitschriftentitel
Chemical Science
Band
14
Ausgabe
46
Seite(n)
13463-13467
ISSN
2041-6520
eISSN
2041-6539
Page URI
https://pub.uni-bielefeld.de/record/2986284
Zitieren
Sun Y, Gerke J, Becker K, et al. Rapid discovery of terpene tailoring enzymes for total biosynthesis. Chemical Science. 2023;14(46):13463-13467.
Sun, Y., Gerke, J., Becker, K., Kuhnert, E., Verwaaijen, B., Wibberg, D., Kalinowski, J., et al. (2023). Rapid discovery of terpene tailoring enzymes for total biosynthesis. Chemical Science, 14(46), 13463-13467. https://doi.org/10.1039/d3sc04172g
Sun, Yunlong, Gerke, Jennifer, Becker, Kevin, Kuhnert, Eric, Verwaaijen, Bart, Wibberg, Daniel, Kalinowski, Jörn, Stadler, Marc, and Cox, Russell J. 2023. “Rapid discovery of terpene tailoring enzymes for total biosynthesis”. Chemical Science 14 (46): 13463-13467.
Sun, Y., Gerke, J., Becker, K., Kuhnert, E., Verwaaijen, B., Wibberg, D., Kalinowski, J., Stadler, M., and Cox, R. J. (2023). Rapid discovery of terpene tailoring enzymes for total biosynthesis. Chemical Science 14, 13463-13467.
Sun, Y., et al., 2023. Rapid discovery of terpene tailoring enzymes for total biosynthesis. Chemical Science, 14(46), p 13463-13467.
Y. Sun, et al., “Rapid discovery of terpene tailoring enzymes for total biosynthesis”, Chemical Science, vol. 14, 2023, pp. 13463-13467.
Sun, Y., Gerke, J., Becker, K., Kuhnert, E., Verwaaijen, B., Wibberg, D., Kalinowski, J., Stadler, M., Cox, R.J.: Rapid discovery of terpene tailoring enzymes for total biosynthesis. Chemical Science. 14, 13463-13467 (2023).
Sun, Yunlong, Gerke, Jennifer, Becker, Kevin, Kuhnert, Eric, Verwaaijen, Bart, Wibberg, Daniel, Kalinowski, Jörn, Stadler, Marc, and Cox, Russell J. “Rapid discovery of terpene tailoring enzymes for total biosynthesis”. Chemical Science 14.46 (2023): 13463-13467.
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