DMPC vesicle structure and dynamics in the presence of low amounts of the saponin aescin
Sreij R, Dargel C, Geisler P, Hertle Y, Radulescu A, Pasini S, Perez J, Hernandez Moleiro L, Hellweg T (2018)
PHYSICAL CHEMISTRY CHEMICAL PHYSICS 20(14): 9070-9083.
Zeitschriftenaufsatz
| Veröffentlicht | Englisch
Download
Es wurden keine Dateien hochgeladen. Nur Publikationsnachweis!
Autor*in
Sreij, RamsiaUniBi;
Dargel, CarinaUniBi;
Geisler, PhilippeUniBi;
Hertle, YvonneUniBi;
Radulescu, Aurel;
Pasini, Stefano;
Perez, Javier;
Hernandez Moleiro, LaraUniBi;
Hellweg, ThomasUniBi
Einrichtung
Abstract / Bemerkung
Vesicle shape and bilayer parameters are studied by small-angle X-ray (SAXS) and small-angle neutron (SANS) scattering in the presence of the saponin aescin. We confirm successful incorporation of aescin molecules by analysis of the radii of gyration RG and study furthermore the impact of aescin incorporation on bilayer thickness parameters from the neutron and X-ray perspective. Additionally, the bending elasticity (k) of these 1,2-dimyristoyl-sn-glycero-3-phosphocholine vesicle bilayers is studied in the presence of aescin. Neutron spin-echo spectroscopy (NSE) allows to detect subtle changes in the dynamics and k of lipid membranes. Changes of k are detectable at temperatures below and above the main phase transition temperature Tm of the lipid. The impact of aescin is much more significant below Tm. It has been found that below Tm the addition of aescin to the vesicles decreases the value of k and softens the bilayer. Above Tm the value of k increases with increasing aescin content and the bilayer becomes more rigid. Altogether, we demonstrate by analysis of the structure and dynamics of the vesicles that the impact of aescin strongly depends on the lipid state. Below Tm the membrane becomes fluidized and softer, above Tm solidified and stiffer compared to a DMPC membrane without additive at similar conditions.
Erscheinungsjahr
2018
Zeitschriftentitel
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
Band
20
Ausgabe
14
Seite(n)
9070-9083
ISSN
1463-9076
eISSN
1463-9084
Page URI
https://pub.uni-bielefeld.de/record/2919290
Zitieren
Sreij R, Dargel C, Geisler P, et al. DMPC vesicle structure and dynamics in the presence of low amounts of the saponin aescin. PHYSICAL CHEMISTRY CHEMICAL PHYSICS. 2018;20(14):9070-9083.
Sreij, R., Dargel, C., Geisler, P., Hertle, Y., Radulescu, A., Pasini, S., Perez, J., et al. (2018). DMPC vesicle structure and dynamics in the presence of low amounts of the saponin aescin. PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 20(14), 9070-9083. doi:10.1039/c7cp08027a
Sreij, Ramsia, Dargel, Carina, Geisler, Philippe, Hertle, Yvonne, Radulescu, Aurel, Pasini, Stefano, Perez, Javier, Hernandez Moleiro, Lara, and Hellweg, Thomas. 2018. “DMPC vesicle structure and dynamics in the presence of low amounts of the saponin aescin”. PHYSICAL CHEMISTRY CHEMICAL PHYSICS 20 (14): 9070-9083.
Sreij, R., Dargel, C., Geisler, P., Hertle, Y., Radulescu, A., Pasini, S., Perez, J., Hernandez Moleiro, L., and Hellweg, T. (2018). DMPC vesicle structure and dynamics in the presence of low amounts of the saponin aescin. PHYSICAL CHEMISTRY CHEMICAL PHYSICS 20, 9070-9083.
Sreij, R., et al., 2018. DMPC vesicle structure and dynamics in the presence of low amounts of the saponin aescin. PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 20(14), p 9070-9083.
R. Sreij, et al., “DMPC vesicle structure and dynamics in the presence of low amounts of the saponin aescin”, PHYSICAL CHEMISTRY CHEMICAL PHYSICS, vol. 20, 2018, pp. 9070-9083.
Sreij, R., Dargel, C., Geisler, P., Hertle, Y., Radulescu, A., Pasini, S., Perez, J., Hernandez Moleiro, L., Hellweg, T.: DMPC vesicle structure and dynamics in the presence of low amounts of the saponin aescin. PHYSICAL CHEMISTRY CHEMICAL PHYSICS. 20, 9070-9083 (2018).
Sreij, Ramsia, Dargel, Carina, Geisler, Philippe, Hertle, Yvonne, Radulescu, Aurel, Pasini, Stefano, Perez, Javier, Hernandez Moleiro, Lara, and Hellweg, Thomas. “DMPC vesicle structure and dynamics in the presence of low amounts of the saponin aescin”. PHYSICAL CHEMISTRY CHEMICAL PHYSICS 20.14 (2018): 9070-9083.
Daten bereitgestellt von European Bioinformatics Institute (EBI)
1 Zitation in Europe PMC
Daten bereitgestellt von Europe PubMed Central.
Aescin-Cholesterol Complexes in DMPC Model Membranes: A DSC and Temperature-Dependent Scattering Study.
Sreij R, Dargel C, Schweins R, Prévost S, Dattani R, Hellweg T., Sci Rep 9(1), 2019
PMID: 30944386
Sreij R, Dargel C, Schweins R, Prévost S, Dattani R, Hellweg T., Sci Rep 9(1), 2019
PMID: 30944386
72 References
Daten bereitgestellt von Europe PubMed Central.
Molecular activities, biosynthesis and evolution of triterpenoid saponins.
Augustin JM, Kuzina V, Andersen SB, Bak S., Phytochemistry 72(6), 2011
PMID: 21333312
Augustin JM, Kuzina V, Andersen SB, Bak S., Phytochemistry 72(6), 2011
PMID: 21333312
Complexation of phospholipids and cholesterol by triterpenic saponins in bulk and in monolayers.
Wojciechowski K, Orczyk M, Gutberlet T, Geue T., Biochim. Biophys. Acta 1858(2), 2015
PMID: 26654784
Wojciechowski K, Orczyk M, Gutberlet T, Geue T., Biochim. Biophys. Acta 1858(2), 2015
PMID: 26654784
Unusual penetration of phospholipid mono- and bilayers by Quillaja bark saponin biosurfactant.
Wojciechowski K, Orczyk M, Gutberlet T, Trapp M, Marcinkowski K, Kobiela T, Geue T., Biochim. Biophys. Acta 1838(7), 2014
PMID: 24746451
Wojciechowski K, Orczyk M, Gutberlet T, Trapp M, Marcinkowski K, Kobiela T, Geue T., Biochim. Biophys. Acta 1838(7), 2014
PMID: 24746451
Exploration of the correlation between the structure, hemolytic activity, and cytotoxicity of steroid saponins.
Wang Y, Zhang Y, Zhu Z, Zhu S, Li Y, Li M, Yu B., Bioorg. Med. Chem. 15(7), 2007
PMID: 17306549
Wang Y, Zhang Y, Zhu Z, Zhu S, Li Y, Li M, Yu B., Bioorg. Med. Chem. 15(7), 2007
PMID: 17306549
Triterpenoid saponins from Quillaja saponaria.
Guo S, Kenne L, Lundgren LN, Ronnberg B, Sundquist BG., Phytochemistry 48(1), 1998
PMID: 9621458
Guo S, Kenne L, Lundgren LN, Ronnberg B, Sundquist BG., Phytochemistry 48(1), 1998
PMID: 9621458
The role of the hydrophobic phase in the unique rheological properties of saponin adsorption layers.
Golemanov K, Tcholakova S, Denkov N, Pelan E, Stoyanov SD., Soft Matter 10(36), 2014
PMID: 24945943
Golemanov K, Tcholakova S, Denkov N, Pelan E, Stoyanov SD., Soft Matter 10(36), 2014
PMID: 24945943
Horse Chestnut - Aesculus Hippocastanum: Potential Applications in Cosmetic Skin-care Products.
Wilkinson JA, Brown AM., Int J Cosmet Sci 21(6), 1999
PMID: 18503457
Wilkinson JA, Brown AM., Int J Cosmet Sci 21(6), 1999
PMID: 18503457
Escin inhibits type I allergic dermatitis in a novel porcine model.
Sipos W, Reutterer B, Frank M, Unger H, Grassauer A, Prieschl-Grassauer E, Doerfler P., Int. Arch. Allergy Immunol. 161(1), 2012
PMID: 23257653
Sipos W, Reutterer B, Frank M, Unger H, Grassauer A, Prieschl-Grassauer E, Doerfler P., Int. Arch. Allergy Immunol. 161(1), 2012
PMID: 23257653
Aescin Incorporation and Nanodomain Formation in DMPC Model Membranes.
Sreij R, Dargel C, Moleiro LH, Monroy F, Hellweg T., Langmuir 33(43), 2017
PMID: 28985678
Sreij R, Dargel C, Moleiro LH, Monroy F, Hellweg T., Langmuir 33(43), 2017
PMID: 28985678
Horse-chestnut seed extract for chronic venous insufficiency. A criteria-based systematic review.
Pittler MH, Ernst E., Arch Dermatol 134(11), 1998
PMID: 9828868
Pittler MH, Ernst E., Arch Dermatol 134(11), 1998
PMID: 9828868
Aescin: pharmacology, pharmacokinetics and therapeutic profile.
Sirtori CR., Pharmacol. Res. 44(3), 2001
PMID: 11529685
Sirtori CR., Pharmacol. Res. 44(3), 2001
PMID: 11529685
Surface activity of saponin from Quillaja bark at the air/water and oil/water interfaces.
Wojciechowski K., Colloids Surf B Biointerfaces 108(), 2013
PMID: 23524082
Wojciechowski K., Colloids Surf B Biointerfaces 108(), 2013
PMID: 23524082
Janiak, J. Biophys. Chem. 254(), 1979
Small-angle neutron scattering from large unilamellar vesicles: an improved method for membrane thickness determination.
Pencer J, Hallett FR., Phys Rev E Stat Phys Plasmas Fluids Relat Interdiscip Topics 61(3), 2000
PMID: 11046629
Pencer J, Hallett FR., Phys Rev E Stat Phys Plasmas Fluids Relat Interdiscip Topics 61(3), 2000
PMID: 11046629
Bilayer thickness and lipid interface area in unilamellar extruded 1,2-diacylphosphatidylcholine liposomes: a small-angle neutron scattering study.
Balgavy P, Dubnickova M, Kucerka N, Kiselev MA, Yaradaikin SP, Uhrikova D., Biochim. Biophys. Acta 1512(1), 2001
PMID: 11334623
Balgavy P, Dubnickova M, Kucerka N, Kiselev MA, Yaradaikin SP, Uhrikova D., Biochim. Biophys. Acta 1512(1), 2001
PMID: 11334623
Does sucrose influence the properties of DMPC vesicles?
Kiselev MA, Wartewig S, Janich M, Lesieur P, Kiselev AM, Ollivon M, Neubert R., Chem. Phys. Lipids 123(1), 2003
PMID: 12637163
Kiselev MA, Wartewig S, Janich M, Lesieur P, Kiselev AM, Ollivon M, Neubert R., Chem. Phys. Lipids 123(1), 2003
PMID: 12637163
Synthetic phospholipid analogs: a structural investigation with scattering methods.
Orthaber D, Glatter O., Chem. Phys. Lipids 107(2), 2000
PMID: 11090847
Orthaber D, Glatter O., Chem. Phys. Lipids 107(2), 2000
PMID: 11090847
Undulations and Dynamic Structure Factor of Membranes.
Zilman AG, Granek R., Phys. Rev. Lett. 77(23), 1996
PMID: 10062631
Zilman AG, Granek R., Phys. Rev. Lett. 77(23), 1996
PMID: 10062631
Zilman, Chem. Phys. 284(), 2002
Bergmann, J. Appl. Crystallogr. 33(), 2000
Mittelbach, J. Appl. Crystallogr. 31(), 1998
Diffuse small-angle scattering of X-rays in colloid systems.
KRATKY O, POROD G., J Colloid Sci 4(1), 1949
PMID: 18110601
KRATKY O, POROD G., J Colloid Sci 4(1), 1949
PMID: 18110601
Glatter, J. Appl. Crystallogr. 13(), 1980
Zhang, Metall. Mater. Trans. A 41(), 2010
Radulescu, Journal of large-scale research facilites 1(), 2015
Fluctuation dynamics of spherical vesicles: frustration of regular bulk dissipation into subdiffusive relaxation.
Arriaga LR, Lopez-Montero I, Orts-Gil G, Farago B, Hellweg T, Monroy F., Phys Rev E Stat Nonlin Soft Matter Phys 80(3 Pt 1), 2009
PMID: 19905147
Arriaga LR, Lopez-Montero I, Orts-Gil G, Farago B, Hellweg T, Monroy F., Phys Rev E Stat Nonlin Soft Matter Phys 80(3 Pt 1), 2009
PMID: 19905147
Influence of charge density on bilayer bending rigidity in lipid vesicles: a combined dynamic light scattering and neutron spin-echo study.
Bruning B, Stehle R, Falus P, Farago B., Eur Phys J E Soft Matter 36(7), 2013
PMID: 23884623
Bruning B, Stehle R, Falus P, Farago B., Eur Phys J E Soft Matter 36(7), 2013
PMID: 23884623
Helfrich, Z. Naturforsch. 28c(), 1973
Dynamical fluctuations of droplet microemulsions and vesicles.
Milner ST, Safran SA., Phys Rev A Gen Phys 36(9), 1987
PMID: 9899393
Milner ST, Safran SA., Phys Rev A Gen Phys 36(9), 1987
PMID: 9899393
Hellweg, Phys. Chem. Chem. Phys. 2(), 2000
Hellweg, Colloids Surf., A 183–185(), 2001
Vesicle fluctuation analysis of the effects of sterols on membrane bending rigidity.
Henriksen J, Rowat AC, Ipsen JH., Eur. Biophys. J. 33(8), 2004
PMID: 15221234
Henriksen J, Rowat AC, Ipsen JH., Eur. Biophys. J. 33(8), 2004
PMID: 15221234
Stiffening effect of cholesterol on disordered lipid phases: a combined neutron spin echo + dynamic light scattering analysis of the bending elasticity of large unilamellar vesicles.
Arriaga LR, Lopez-Montero I, Monroy F, Orts-Gil G, Farago B, Hellweg T., Biophys. J. 96(9), 2009
PMID: 19413968
Arriaga LR, Lopez-Montero I, Monroy F, Orts-Gil G, Farago B, Hellweg T., Biophys. J. 96(9), 2009
PMID: 19413968
Dissipative curvature fluctuations in bilayer vesicles: Coexistence of pure-bending and hybrid curvature-compression modes.
Arriaga LR, Rodriguez-Garcia R, Lopez-Montero I, Farago B, Hellweg T, Monroy F., Eur Phys J E Soft Matter 31(1), 2010
PMID: 20087620
Arriaga LR, Rodriguez-Garcia R, Lopez-Montero I, Farago B, Hellweg T, Monroy F., Eur Phys J E Soft Matter 31(1), 2010
PMID: 20087620
Lipid bilayers and membrane dynamics: insight into thickness fluctuations.
Woodka AC, Butler PD, Porcar L, Farago B, Nagao M., Phys. Rev. Lett. 109(5), 2012
PMID: 23006210
Woodka AC, Butler PD, Porcar L, Farago B, Nagao M., Phys. Rev. Lett. 109(5), 2012
PMID: 23006210
Marignan, J. Phys. 50(), 1989
Gazeau, Europhys. Lett. 9(), 1989
Van, Phys. Rev. 95(), 1954
Holderer, Meas. Sci. Technol. 19(), 2008
Berne, 2000
Provencher, Comput. Phys. Commun. 27(), 1982
Guinier, 1955
Knoll, J. Appl. Crystallogr. 14(), 1981
Glatter, 0
Effect of extrusion pressure and lipid properties on the size and polydispersity of lipid vesicles.
Hunter DG, Frisken BJ., Biophys. J. 74(6), 1998
PMID: 9635753
Hunter DG, Frisken BJ., Biophys. J. 74(6), 1998
PMID: 9635753
Areas of monounsaturated diacylphosphatidylcholines.
Kucerka N, Gallova J, Uhrikova D, Balgavy P, Bulacu M, Marrink SJ, Katsaras J., Biophys. J. 97(7), 2009
PMID: 19804723
Kucerka N, Gallova J, Uhrikova D, Balgavy P, Bulacu M, Marrink SJ, Katsaras J., Biophys. J. 97(7), 2009
PMID: 19804723
Scattering density profile model of POPG bilayers as determined by molecular dynamics simulations and small-angle neutron and X-ray scattering experiments.
Kucerka N, Holland BW, Gray CG, Tomberli B, Katsaras J., J Phys Chem B 116(1), 2011
PMID: 22107350
Kucerka N, Holland BW, Gray CG, Tomberli B, Katsaras J., J Phys Chem B 116(1), 2011
PMID: 22107350
Analysis of Quil A-phospholipid mixtures using drift spectroscopy.
Demana PH, Davies NM, Hook S, Rades T., Int J Pharm 342(1-2), 2007
PMID: 17555894
Demana PH, Davies NM, Hook S, Rades T., Int J Pharm 342(1-2), 2007
PMID: 17555894
The membrane-activity of Ibuprofen, Diclofenac, and Naproxen: a physico-chemical study with lecithin phospholipids.
Manrique-Moreno M, Moreno MM, Garidel P, Suwalsky M, Howe J, Brandenburg K., Biochim. Biophys. Acta 1788(6), 2009
PMID: 19366589
Manrique-Moreno M, Moreno MM, Garidel P, Suwalsky M, Howe J, Brandenburg K., Biochim. Biophys. Acta 1788(6), 2009
PMID: 19366589
Action of saponin on biological cell membranes.
BANGHAM AD, HORNE RW, GLAUERT AM, DINGLE JT, LUCY JA., Nature 196(), 1962
PMID: 13966357
BANGHAM AD, HORNE RW, GLAUERT AM, DINGLE JT, LUCY JA., Nature 196(), 1962
PMID: 13966357
Saponins can perturb biologic membranes and reduce the surface tension of aqueous solutions: a correlation?
Bottger S, Hofmann K, Melzig MF., Bioorg. Med. Chem. 20(9), 2012
PMID: 22503361
Bottger S, Hofmann K, Melzig MF., Bioorg. Med. Chem. 20(9), 2012
PMID: 22503361
Electron microscopic observations on Rous sarcoma virus and cell membranes.
DOURMASHKIN RR, DOUGHERTY RM, HARRIS RJ., Nature 194(), 1962
PMID: 13887581
DOURMASHKIN RR, DOUGHERTY RM, HARRIS RJ., Nature 194(), 1962
PMID: 13887581
Self-Assembly of Escin Molecules at the Air-Water Interface as Studied by Molecular Dynamics.
Tsibranska S, Ivanova A, Tcholakova S, Denkov N., Langmuir 33(33), 2017
PMID: 28749143
Tsibranska S, Ivanova A, Tcholakova S, Denkov N., Langmuir 33(33), 2017
PMID: 28749143
Small-angle neutron scattering studies of phospholipid-NSAID adducts.
Boggara MB, Krishnamoorti R., Langmuir 26(8), 2010
PMID: 20014785
Boggara MB, Krishnamoorti R., Langmuir 26(8), 2010
PMID: 20014785
Weber, 2007
Dynamics in the plasma membrane: how to combine fluidity and order.
Marguet D, Lenne PF, Rigneault H, He HT., EMBO J. 25(15), 2006
PMID: 16900097
Marguet D, Lenne PF, Rigneault H, He HT., EMBO J. 25(15), 2006
PMID: 16900097
Yi, J. Phys.: Conf. Ser. 251(), 2010
Effect of pH and ibuprofen on the phospholipid bilayer bending modulus.
Boggara MB, Faraone A, Krishnamoorti R., J Phys Chem B 114(24), 2010
PMID: 20518571
Boggara MB, Faraone A, Krishnamoorti R., J Phys Chem B 114(24), 2010
PMID: 20518571
Bending stiffness of biological membranes: what can be measured by neutron spin echo?
Mell M, Moleiro LH, Hertle Y, Fouquet P, Schweins R, Lopez-Montero I, Hellweg T, Monroy F., Eur Phys J E Soft Matter 36(7), 2013
PMID: 23852577
Mell M, Moleiro LH, Hertle Y, Fouquet P, Schweins R, Lopez-Montero I, Hellweg T, Monroy F., Eur Phys J E Soft Matter 36(7), 2013
PMID: 23852577
Bilayer undulation dynamics in unilamellar phospholipid vesicles: effect of temperature, cholesterol and trehalose.
Bruning BA, Prevost S, Stehle R, Steitz R, Falus P, Farago B, Hellweg T., Biochim. Biophys. Acta 1838(10), 2014
PMID: 24950248
Bruning BA, Prevost S, Stehle R, Steitz R, Falus P, Farago B, Hellweg T., Biochim. Biophys. Acta 1838(10), 2014
PMID: 24950248
Bending elasticities of model membranes: influences of temperature and sterol content.
Meleard P, Gerbeaud C, Pott T, Fernandez-Puente L, Bivas I, Mitov MD, Dufourcq J, Bothorel P., Biophys. J. 72(6), 1997
PMID: 9168037
Meleard P, Gerbeaud C, Pott T, Fernandez-Puente L, Bivas I, Mitov MD, Dufourcq J, Bothorel P., Biophys. J. 72(6), 1997
PMID: 9168037
Du, Electrochim. Acta 51(), 2006
Yi, Biophys. J. 160(), 2012
Yi, J. Phys.: Condens. Matter 21(), 2009
Elastic curvature constants of lipid monolayers and bilayers.
Marsh D., Chem. Phys. Lipids 144(2), 2006
PMID: 17045578
Marsh D., Chem. Phys. Lipids 144(2), 2006
PMID: 17045578
Nanosecond lipid dynamics in membranes containing cholesterol.
Armstrong CL, Haussler W, Seydel T, Katsaras J, Rheinstadter MC., Soft Matter 10(15), 2014
PMID: 24647350
Armstrong CL, Haussler W, Seydel T, Katsaras J, Rheinstadter MC., Soft Matter 10(15), 2014
PMID: 24647350
Fluctuation dynamics of bilayer vesicles with intermonolayer sliding: experiment and theory.
Mell M, Moleiro LH, Hertle Y, Lopez-Montero I, Cao FJ, Fouquet P, Hellweg T, Monroy F., Chem. Phys. Lipids 185(), 2014
PMID: 25455136
Mell M, Moleiro LH, Hertle Y, Lopez-Montero I, Cao FJ, Fouquet P, Hellweg T, Monroy F., Chem. Phys. Lipids 185(), 2014
PMID: 25455136
All-optical measurements of the bending rigidity of lipid-vesicle membranes across structural phase transitions.
Lee CH, Lin WC, Wang J., Phys Rev E Stat Nonlin Soft Matter Phys 64(2 Pt 1), 2001
PMID: 11497555
Lee CH, Lin WC, Wang J., Phys Rev E Stat Nonlin Soft Matter Phys 64(2 Pt 1), 2001
PMID: 11497555
Marquardt, J. Soc. Ind. Appl. Math. 11(), 1963
Levenberg, Q. Appl. Math. 2(), 1944
Dellnitz, J. Optim. Theory Appl. 124(), 2005
The influence of cholesterol on the main phase transition of unilamellar dipalmytoylphosphatidylcholine vesicles. A differential scanning calorimetry and iodine laser T-jump study.
Genz A, Holzwarth JF, Tsong TY., Biophys. J. 50(6), 1986
PMID: 3801567
Genz A, Holzwarth JF, Tsong TY., Biophys. J. 50(6), 1986
PMID: 3801567
Material in PUB:
Teil dieser Dissertation
Self-Assembly in Phospolipid-Saponin Mixtures. From Small Unilamellar Vesicles to Bicelles
Dargel C (2019)
Bielefeld: Universität Bielefeld.
Dargel C (2019)
Bielefeld: Universität Bielefeld.
Teil dieser Dissertation
Structure & dynamics of DMPC model membranes in the presence of the saponin β-aescin. With and without additives
Sreij R (2018)
Bielefeld: Universität Bielefeld.
Sreij R (2018)
Bielefeld: Universität Bielefeld.
Export
Markieren/ Markierung löschen
Markierte Publikationen
Web of Science
Dieser Datensatz im Web of Science®Quellen
PMID: 29505043
PubMed | Europe PMC
Suchen in