PUB - Publikationen an der Universität Bielefeld

Lithistid sponges: Star performers or hosts to the stars
Bewley CA, Faulkner DJ., 1998

Polytheonamides A and B, highly cytotoxic, linear polypeptides with unprecedented structural features, from the marine sponge, Theonella swinhoei.
Hamada T, Matsunaga S, Yano G, Fusetani N., J. Am. Chem. Soc. 127(1), 2005
PMID: 15631460

Sterols in marine invertebrates. 22. Isolation and structure elucidation of conicasterol and theonellasterol, two new 4-methylene sterols from the Red Sea sponges Theonella conica and Theonella swinhoei
Kho E, Imagawa DK, Rohmer M, Kashman Y, Djerassi C., 1981

A serendipitous discovery of isomotuporin-containing sponge populations of Theonella swinhoei.
Wegerski CJ, Hammond J, Tenney K, Matainaho T, Crews P., J. Nat. Prod. 70(1), 2007
PMID: 17253855

Molecular evidence for a uniform microbial community in sponges from different oceans.
Hentschel U, Hopke J, Horn M, Friedrich AB, Wagner M, Hacker J, Moore BS., Appl. Environ. Microbiol. 68(9), 2002
PMID: 12200297

Sponge-associated microorganisms: evolution, ecology, and biotechnological potential.
Taylor MW, Radax R, Steger D, Wagner M., Microbiol. Mol. Biol. Rev. 71(2), 2007
PMID: 17554047

Metabolites from symbiotic bacteria.
Piel J., Nat Prod Rep 21(4), 2004
PMID: 15282634

New metabolites from marine sponges:–Are symbionts important
Faulkner D, He H, Unson M, Bewley C, Garson M., 1993

Theopalauamide, a bicyclic glycopeptide from filamentous bacterial symbionts of the lithistid sponge Theonella swinhoei from Palau and Mozambique
Schmidt EW, Bewley CA, Faulkner DJ., 1998

Structure of swinholide A, a new macrolide from the marine sponge Theonella swinhoei
Carmely S, Kashman Y., 1985

Two classes of metabolites from Theonella swinhoei are localized in distinct populations of bacterial symbionts.
Bewley CA, Holland ND, Faulkner DJ., Experientia 52(7), 1996
PMID: 8698116

Identification of the antifungal peptide-containing symbiont of the marine sponge Theonella swinhoei as a novel δ-proteobacterium, “Candidatus Entotheonella palauensis
Schmidt EW, Obraztsova AY, Davidson SK, Faulkner DJ, Haygood MG., 2000

Antitumor polyketide biosynthesis by an uncultivated bacterial symbiont of the marine sponge Theonella swinhoei.
Piel J, Hui D, Wen G, Butzke D, Platzer M, Fusetani N, Matsunaga S., Proc. Natl. Acad. Sci. U.S.A. 101(46), 2004
PMID: 15520376

Metagenome mining reveals polytheonamides as posttranslationally modified ribosomal peptides.
Freeman MF, Gurgui C, Helf MJ, Morinaka BI, Uria AR, Oldham NJ, Sahl HG, Matsunaga S, Piel J., Science 338(6105), 2012
PMID: 22983711

An environmental bacterial taxon with a large and distinct metabolic repertoire.
Wilson MC, Mori T, Ruckert C, Uria AR, Helf MJ, Takada K, Gernert C, Steffens UA, Heycke N, Schmitt S, Rinke C, Helfrich EJ, Brachmann AO, Gurgui C, Wakimoto T, Kracht M, Crusemann M, Hentschel U, Abe I, Matsunaga S, Kalinowski J, Takeyama H, Piel J., Nature 506(7486), 2014
PMID: 24476823

Seven enzymes create extraordinary molecular complexity in an uncultivated bacterium.
Freeman MF, Helf MJ, Bhushan A, Morinaka BI, Piel J., Nat Chem 9(4), 2016
PMID: 28338684

Isolation and structure elucidation of onnamide A, a new bioactive metabolite of a marine sponge, Theonella sp
Sakemi S, Ichiba T, Kohmoto S, Saucy G, Higa T., 1988

Orbiculamide A: A novel cytotoxic cyclic peptide from a marine sponge Theonella sp
Fusetani N, Sugawara T, Matsunaga S, Hirota H., 1991

Keramamide A, a novel peptide from the Okinawan marine sponge Theonella sp
Ji K., 1991

Bioactive marine metabolites. 33. Cyclotheonamides, potent thrombin inhibitors, from a marine sponge Theonella sp
Fusetani N, Matsunaga S, Matsumoto H, Takebayashi Y., 1990

Nazumamide A, a thrombin-inhibitory tetrapeptide, from a marine sponge, Theonella sp
Fusetani N, Nakao Y, Matsunaga S., 1991

Insights into the lifestyle of uncultured bacterial natural product factories associated with marine sponges.
Lackner G, Peters EE, Helfrich EJ, Piel J., Proc. Natl. Acad. Sci. U.S.A. 114(3), 2017
PMID: 28049838

Enzyme from an Uncultivated Sponge Bacterium Catalyzes S-Methylation in a Ribosomal Peptide.
Helf MJ, Jud A, Piel J., Chembiochem 18(5), 2017
PMID: 27966282

Misakinolide A, an antitumor macrolide from the marine sponge Theonella sp
Sakai R, Higa T, Kashman Y., 1986

Antitumor macrodiolides isolated from a marine sponge Theonella sp.: Structure revision of misakinolide A
Kato Y., 1987

Theonellamide F. A novel antifungal bicyclic peptide from a marine sponge Theonella sp
Matsunaga S, Fusetani N, Hashimoto K, Walchli M., 1989

Theonellamides A-E, cytotoxic bicyclic peptides, from a marine sponge Theonella sp
Matsunaga S, Fusetani N., 1995

Metabolic and evolutionary origin of actin-binding polyketides from diverse organisms.
Ueoka R, Uria AR, Reiter S, Mori T, Karbaum P, Peters EE, Helfrich EJ, Morinaka BI, Gugger M, Takeyama H, Matsunaga S, Piel J., Nat. Chem. Biol. 11(9), 2015
PMID: 26236936

antiSMASH 3.0-a comprehensive resource for the genome mining of biosynthetic gene clusters.
Weber T, Blin K, Duddela S, Krug D, Kim HU, Bruccoleri R, Lee SY, Fischbach MA, Muller R, Wohlleben W, Breitling R, Takano E, Medema MH., Nucleic Acids Res. 43(W1), 2015
PMID: 25948579

The natural product domain seeker NaPDoS: a phylogeny based bioinformatic tool to classify secondary metabolite gene diversity.
Ziemert N, Podell S, Penn K, Badger JH, Allen E, Jensen PR., PLoS ONE 7(3), 2012
PMID: 22479523

NRPSpredictor2--a web server for predicting NRPS adenylation domain specificity.
Rottig M, Medema MH, Blin K, Weber T, Rausch C, Kohlbacher O., Nucleic Acids Res. 39(Web Server issue), 2011
PMID: 21558170

The specificity-conferring code of adenylation domains in nonribosomal peptide synthetases.
Stachelhaus T, Mootz HD, Marahiel MA., Chem. Biol. 6(8), 1999
PMID: 10421756

Predictive, structure-based model of amino acid recognition by nonribosomal peptide synthetase adenylation domains.
Challis GL, Ravel J, Townsend CA., Chem. Biol. 7(3), 2000
PMID: 10712928

Sequencing genomes from single cells by polymerase cloning.
Zhang K, Martiny AC, Reppas NB, Barry KW, Malek J, Chisholm SW, Church GM., Nat. Biotechnol. 24(6), 2006
PMID: 16732271

Chain initiation on the soraphen-producing modular polyketide synthase from Sorangium cellulosum.
Wilkinson CJ, Frost EJ, Staunton J, Leadlay PF., Chem. Biol. 8(12), 2001
PMID: 11755398

The enduracidin biosynthetic gene cluster from Streptomyces fungicidicus.
Yin X, Zabriskie TM., Microbiology (Reading, Engl.) 152(Pt 10), 2006
PMID: 17005978

Characterization of the syringomycin synthetase gene cluster. A link between prokaryotic and eukaryotic peptide synthetases.
Guenzi E, Galli G, Grgurina I, Gross DC, Grandi G., J. Biol. Chem. 273(49), 1998
PMID: 9830033

Lysine biosynthesis in Saccharomyces cerevisiae: mechanism of alpha-aminoadipate reductase (Lys2) involves posttranslational phosphopantetheinylation by Lys5.
Ehmann DE, Gehring AM, Walsh CT., Biochemistry 38(19), 1999
PMID: 10320345

MS/MS networking guided analysis of molecule and gene cluster families.
Nguyen DD, Wu CH, Moree WJ, Lamsa A, Medema MH, Zhao X, Gavilan RG, Aparicio M, Atencio L, Jackson C, Ballesteros J, Sanchez J, Watrous JD, Phelan VV, van de Wiel C, Kersten RD, Mehnaz S, De Mot R, Shank EA, Charusanti P, Nagarajan H, Duggan BM, Moore BS, Bandeira N, Palsson BO, Pogliano K, Gutierrez M, Dorrestein PC., Proc. Natl. Acad. Sci. U.S.A. 110(28), 2013
PMID: 23798442

Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking.
Wang M, Carver JJ, Phelan VV, Sanchez LM, Garg N, Peng Y, Nguyen DD, Watrous J, Kapono CA, Luzzatto-Knaan T, Porto C, Bouslimani A, Melnik AV, Meehan MJ, Liu WT, Crusemann M, Boudreau PD, Esquenazi E, Sandoval-Calderon M, Kersten RD, Pace LA, Quinn RA, Duncan KR, Hsu CC, Floros DJ, Gavilan RG, Kleigrewe K, Northen T, Dutton RJ, Parrot D, Carlson EE, Aigle B, Michelsen CF, Jelsbak L, Sohlenkamp C, Pevzner P, Edlund A, McLean J, Piel J, Murphy BT, Gerwick L, Liaw CC, Yang YL, Humpf HU, Maansson M, Keyzers RA, Sims AC, Johnson AR, Sidebottom AM, Sedio BE, Klitgaard A, Larson CB, P CAB, Torres-Mendoza D, Gonzalez DJ, Silva DB, Marques LM, Demarque DP, Pociute E, O'Neill EC, Briand E, Helfrich EJN, Granatosky EA, Glukhov E, Ryffel F, Houson H, Mohimani H, Kharbush JJ, Zeng Y, Vorholt JA, Kurita KL, Charusanti P, McPhail KL, Nielsen KF, Vuong L, Elfeki M, Traxler MF, Engene N, Koyama N, Vining OB, Baric R, Silva RR, Mascuch SJ, Tomasi S, Jenkins S, Macherla V, Hoffman T, Agarwal V, Williams PG, Dai J, Neupane R, Gurr J, Rodriguez AMC, Lamsa A, Zhang C, Dorrestein K, Duggan BM, Almaliti J, Allard PM, Phapale P, Nothias LF, Alexandrov T, Litaudon M, Wolfender JL, Kyle JE, Metz TO, Peryea T, Nguyen DT, VanLeer D, Shinn P, Jadhav A, Muller R, Waters KM, Shi W, Liu X, Zhang L, Knight R, Jensen PR, Palsson BO, Pogliano K, Linington RG, Gutierrez M, Lopes NP, Gerwick WH, Moore BS, Dorrestein PC, Bandeira N., Nat. Biotechnol. 34(8), 2016
PMID: 27504778

Calyculin biogenesis from a pyrophosphate protoxin produced by a sponge symbiont.
Wakimoto T, Egami Y, Nakashima Y, Wakimoto Y, Mori T, Awakawa T, Ito T, Kenmoku H, Asakawa Y, Piel J, Abe I., Nat. Chem. Biol. 10(8), 2014
PMID: 24974231

Metagenomic Analysis of the Sponge Discodermia Reveals the Production of the Cyanobacterial Natural Product Kasumigamide by 'Entotheonella'.
Nakashima Y, Egami Y, Kimura M, Wakimoto T, Abe I., PLoS ONE 11(10), 2016
PMID: 27732651

Identification of the bacterial symbiont Entotheonella sp. in the mesohyl of the marine sponge Discodermia sp.
Bruck WM, Sennett SH, Pomponi SA, Willenz P, McCarthy PJ., ISME J 2(3), 2008
PMID: 18256706

Isolation of swinholide A and related glycosylated derivatives from two field collections of marine cyanobacteria.
Andrianasolo EH, Gross H, Goeger D, Musafija-Girt M, McPhail K, Leal RM, Mooberry SL, Gerwick WH., Org. Lett. 7(7), 2005
PMID: 15787510

The Swinholide Biosynthesis Gene Cluster from a Terrestrial Cyanobacterium, Nostoc sp. Strain UHCC 0450.
Humisto A, Jokela J, Liu L, Wahlsten M, Wang H, Permi P, Machado JP, Antunes A, Fewer DP, Sivonen K., Appl. Environ. Microbiol. 84(3), 2018
PMID: 29150506

A brominated secondary metabolite synthesized by the cyanobacterial symbiont of a marine sponge and accumulation of the crystalline metabolite in the sponge tissue
Unson MD, Holland ND, Faulkner DJ., 1994

Metagenomic discovery of polybrominated diphenyl ether biosynthesis by marine sponges.
Agarwal V, Blanton JM, Podell S, Taton A, Schorn MA, Busch J, Lin Z, Schmidt EW, Jensen PR, Paul VJ, Biggs JS, Golden JW, Allen EE, Moore BS., Nat. Chem. Biol. 13(5), 2017
PMID: 28319100