Categorization of two-photon microscopy images of human cartilage into states of osteoarthritis

Bergmann T, Maeder U, Fiebich M, Dickob M, Nattkemper TW, Anselmetti D (2013)
Osteoarthritis And Cartilage 21(8): 1074-1082.

Zeitschriftenaufsatz | Veröffentlicht | Englisch
 
Download
Es wurde kein Volltext hochgeladen. Nur Publikationsnachweis!
Autor/in
Abstract / Bemerkung
Objective: The degeneration of articular cartilage is part of the clinical syndrome of osteoarthritis (OA) and one of the most common causes of pain and disability in middle-aged and older people(1). However, the objective detection of an initial state of OA is still challenging. In order to categorize cartilage into states of OA, an algorithm is presented which offers objective categorization on the basis of two-photon laser-scanning microscopy (TPLSM) images. Methods: The algorithm is based on morphological characteristics of the images and results in a topographical visualization. This paper describes the algorithm and shows the result of a categorization of human cartilage samples. Results: The resulting map of the analysis of TPLSM images can be divided into areas which correspond to the grades of the Outerbridge-Categorization. The algorithm is able to differentiate the samples in coincidence with the macroscopic impression. Conclusion: The method is promising for early OA detection and categorization. In order to achieve a higher benefit for the physician the method must be transferred to an endoscopic setup for an application in surgery. (C) 2013 Osteoarthritis Research Society International. Published by Elsevier Ltd. All rights reserved.
Stichworte
Wavelet; Self-organizing maps; Cartilage; Osteoarthritis; Categorization; 2-Photon microscopy; transformation
Erscheinungsjahr
2013
Zeitschriftentitel
Osteoarthritis And Cartilage
Band
21
Ausgabe
8
Seite(n)
1074-1082
ISSN
1063-4584
Page URI
https://pub.uni-bielefeld.de/record/2625914

Zitieren

Bergmann T, Maeder U, Fiebich M, Dickob M, Nattkemper TW, Anselmetti D. Categorization of two-photon microscopy images of human cartilage into states of osteoarthritis. Osteoarthritis And Cartilage. 2013;21(8):1074-1082.
Bergmann, T., Maeder, U., Fiebich, M., Dickob, M., Nattkemper, T. W., & Anselmetti, D. (2013). Categorization of two-photon microscopy images of human cartilage into states of osteoarthritis. Osteoarthritis And Cartilage, 21(8), 1074-1082. doi:10.1016/j.joca.2013.04.019
Bergmann, T., Maeder, U., Fiebich, M., Dickob, M., Nattkemper, T. W., and Anselmetti, D. (2013). Categorization of two-photon microscopy images of human cartilage into states of osteoarthritis. Osteoarthritis And Cartilage 21, 1074-1082.
Bergmann, T., et al., 2013. Categorization of two-photon microscopy images of human cartilage into states of osteoarthritis. Osteoarthritis And Cartilage, 21(8), p 1074-1082.
T. Bergmann, et al., “Categorization of two-photon microscopy images of human cartilage into states of osteoarthritis”, Osteoarthritis And Cartilage, vol. 21, 2013, pp. 1074-1082.
Bergmann, T., Maeder, U., Fiebich, M., Dickob, M., Nattkemper, T.W., Anselmetti, D.: Categorization of two-photon microscopy images of human cartilage into states of osteoarthritis. Osteoarthritis And Cartilage. 21, 1074-1082 (2013).
Bergmann, Thorsten, Maeder, U., Fiebich, M., Dickob, M., Nattkemper, Tim Wilhelm, and Anselmetti, Dario. “Categorization of two-photon microscopy images of human cartilage into states of osteoarthritis”. Osteoarthritis And Cartilage 21.8 (2013): 1074-1082.

Export

Markieren/ Markierung löschen
Markierte Publikationen

Open Data PUB

Web of Science

Dieser Datensatz im Web of Science®

Quellen

PMID: 23680876
PubMed | Europe PMC

Suchen in

Google Scholar