Comparative genomics of Lactobacillus

Kant R, Blom J, Palva A, Siezen RJ, de Vos WM (2011)
Microbial Biotechnology 4(3): 323-332.

Zeitschriftenaufsatz | Veröffentlicht | Englisch
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Kant, Ravi; Blom, JochenUniBi; Palva, Airi; Siezen, Roland J.; de Vos, Willem M.
Abstract / Bemerkung
P>The genus Lactobacillus includes a diverse group of bacteria consisting of many species that are associated with fermentations of plants, meat or milk. In addition, various lactobacilli are natural inhabitants of the intestinal tract of humans and other animals. Finally, several Lactobacillus strains are marketed as probiotics as their consumption can confer a health benefit to host. Presently, 154 Lactobacillus species are known and a growing fraction of these are subject to draft genome sequencing. However, complete genome sequences are needed to provide a platform for detailed genomic comparisons. Therefore, we selected a total of 20 genomes of various Lactobacillus strains for which complete genomic sequences have been reported. These genomes had sizes varying from 1.8 to 3.3 Mb and other characteristic features, such as G+C content that ranged from 33% to 51%. The Lactobacillus pan genome was found to consist of approximately 14 000 protein-encoding genes while all 20 genomes shared a total of 383 sets of orthologous genes that defined the Lactobacillus core genome (LCG). Based on advanced phylogeny of the proteins encoded by this LCG, we grouped the 20 strains into three main groups and defined core group genes present in all genomes of a single group, signature group genes shared in all genomes of one group but absent in all other Lactobacillus genomes, and Group-specific ORFans present in core group genes of one group and absent in all other complete genomes. The latter are of specific value in defining the different groups of genomes. The study provides a platform for present individual comparisons as well as future analysis of new Lactobacillus genomes.
Microbial Biotechnology
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Kant R, Blom J, Palva A, Siezen RJ, de Vos WM. Comparative genomics of Lactobacillus. Microbial Biotechnology. 2011;4(3):323-332.
Kant, R., Blom, J., Palva, A., Siezen, R. J., & de Vos, W. M. (2011). Comparative genomics of Lactobacillus. Microbial Biotechnology, 4(3), 323-332.
Kant, Ravi, Blom, Jochen, Palva, Airi, Siezen, Roland J., and de Vos, Willem M. 2011. “Comparative genomics of Lactobacillus”. Microbial Biotechnology 4 (3): 323-332.
Kant, R., Blom, J., Palva, A., Siezen, R. J., and de Vos, W. M. (2011). Comparative genomics of Lactobacillus. Microbial Biotechnology 4, 323-332.
Kant, R., et al., 2011. Comparative genomics of Lactobacillus. Microbial Biotechnology, 4(3), p 323-332.
R. Kant, et al., “Comparative genomics of Lactobacillus”, Microbial Biotechnology, vol. 4, 2011, pp. 323-332.
Kant, R., Blom, J., Palva, A., Siezen, R.J., de Vos, W.M.: Comparative genomics of Lactobacillus. Microbial Biotechnology. 4, 323-332 (2011).
Kant, Ravi, Blom, Jochen, Palva, Airi, Siezen, Roland J., and de Vos, Willem M. “Comparative genomics of Lactobacillus”. Microbial Biotechnology 4.3 (2011): 323-332.

48 Zitationen in Europe PMC

Daten bereitgestellt von Europe PubMed Central.

Uncovering carbohydrate metabolism through a genotype-phenotype association study of 56 lactic acid bacteria genomes.
Buron-Moles G, Chailyan A, Dolejs I, Forster J, Mikš MH., Appl Microbiol Biotechnol 103(7), 2019
PMID: 30830251
Comparative genome analysis of the Lactobacillus brevis species.
Feyereisen M, Mahony J, Kelleher P, Roberts RJ, O'Sullivan T, Geertman JA, van Sinderen D., BMC Genomics 20(1), 2019
PMID: 31122208
Comparative genome analysis of 24 bovine-associated Staphylococcus isolates with special focus on the putative virulence genes.
Åvall-Jääskeläinen S, Taponen S, Kant R, Paulin L, Blom J, Palva A, Koort J., PeerJ 6(), 2018
PMID: 29610707
Gut Microbiota and Endothelial Dysfunction Markers in Obese Mexican Children and Adolescents.
Nirmalkar K, Murugesan S, Pizano-Zárate ML, Villalobos-Flores LE, García-González C, Morales-Hernández RM, Nuñez-Hernández JA, Hernández-Quiroz F, Romero-Figueroa MDS, Hernández-Guerrero C, Hoyo-Vadillo C, García-Mena J., Nutrients 10(12), 2018
PMID: 30572569
A Cryptic Non-Inducible Prophage Confers Phage-Immunity on the Streptococcus thermophilus M17PTZA496.
da Silva Duarte V, Giaretta S, Campanaro S, Treu L, Armani A, Tarrah A, Oliveira de Paula S, Giacomini A, Corich V., Viruses 11(1), 2018
PMID: 30583530
Advances in the genomics and metabolomics of dairy lactobacilli: A review.
Stefanovic E, Fitzgerald G, McAuliffe O., Food Microbiol 61(), 2017
PMID: 27697167
A novel real-time PCR assay for highly specific detection and quantification of vaginal lactobacilli.
Demkin VV, Koshechkin SI, Slesarev A., Mol Cell Probes 32(), 2017
PMID: 27890610
Microbiota alteration is associated with the development of stress-induced despair behavior.
Marin IA, Goertz JE, Ren T, Rich SS, Onengut-Gumuscu S, Farber E, Wu M, Overall CC, Kipnis J, Gaultier A., Sci Rep 7(), 2017
PMID: 28266612
Complete and Assembled Genome Sequence of Lactobacillus plantarum RI-113 Isolated from Salami.
Inglin RC, Meile L, Klumpp J, Stevens MJA., Genome Announc 5(16), 2017
PMID: 28428294
Phylogenomics and comparative genomics of Lactobacillus salivarius, a mammalian gut commensal.
Harris HMB, Bourin MJB, Claesson MJ, O'Toole PW., Microb Genom 3(8), 2017
PMID: 29026656
Identification of a mouse Lactobacillus johnsonii strain with deconjugase activity against the FXR antagonist T-β-MCA.
DiMarzio M, Rusconi B, Yennawar NH, Eppinger M, Patterson AD, Dudley EG., PLoS One 12(9), 2017
PMID: 28910295
Do advanced glycation end-products cause food allergy?
Smith PK., Curr Opin Allergy Clin Immunol 17(5), 2017
PMID: 28786835
Lactobacillus acidophilus Metabolizes Dietary Plant Glucosides and Externalizes Their Bioactive Phytochemicals.
Theilmann MC, Goh YJ, Nielsen KF, Klaenhammer TR, Barrangou R, Abou Hachem M., MBio 8(6), 2017
PMID: 29162708
Microbial bioinformatics for food safety and production.
Alkema W, Boekhorst J, Wels M, van Hijum SA., Brief Bioinform 17(2), 2016
PMID: 26082168
Functional Analysis of an S-Layer-Associated Fibronectin-Binding Protein in Lactobacillus acidophilus NCFM.
Hymes JP, Johnson BR, Barrangou R, Klaenhammer TR., Appl Environ Microbiol 82(9), 2016
PMID: 26921419
Chemical characterization and immunomodulatory properties of polysaccharides isolated from probiotic Lactobacillus casei LOCK 0919.
Górska S, Hermanova P, Ciekot J, Schwarzer M, Srutkova D, Brzozowska E, Kozakova H, Gamian A., Glycobiology 26(9), 2016
PMID: 27102285
Draft Whole-Genome Sequences of Three Lactobacillus plantarum Food Isolates.
Fernández Ramírez MD, Boekhorst J, de Jong A, Kuipers OP, Abee T, Nierop Groot MN., Genome Announc 4(3), 2016
PMID: 27313301
Comparative Genomics Reveals Biomarkers to Identify Lactobacillus Species.
Koul S, Kalia VC., Indian J Microbiol 56(3), 2016
PMID: 27407290
The Variable Regions of Lactobacillus rhamnosus Genomes Reveal the Dynamic Evolution of Metabolic and Host-Adaptation Repertoires.
Ceapa C, Davids M, Ritari J, Lambert J, Wels M, Douillard FP, Smokvina T, de Vos WM, Knol J, Kleerebezem M., Genome Biol Evol 8(6), 2016
PMID: 27358423
Profiles and technological requirements of urogenital probiotics.
Nader-Macías ME, Juárez Tomás MS., Adv Drug Deliv Rev 92(), 2015
PMID: 25858665
Extensive intra-phylotype diversity in lactobacilli and bifidobacteria from the honeybee gut.
Ellegaard KM, Tamarit D, Javelind E, Olofsson TC, Andersson SG, Vásquez A., BMC Genomics 16(), 2015
PMID: 25880915
Survey of compound microsatellites in multiple Lactobacillus genomes.
Basharat Z, Yasmin A., Can J Microbiol 61(12), 2015
PMID: 26445296
Expanding the biotechnology potential of lactobacilli through comparative genomics of 213 strains and associated genera.
Sun Z, Harris HM, McCann A, Guo C, Argimón S, Zhang W, Yang X, Jeffery IB, Cooney JC, Kagawa TF, Liu W, Song Y, Salvetti E, Wrobel A, Rasinkangas P, Parkhill J, Rea MC, O'Sullivan O, Ritari J, Douillard FP, Paul Ross R, Yang R, Briner AE, Felis GE, de Vos WM, Barrangou R, Klaenhammer TR, Caufield PW, Cui Y, Zhang H, O'Toole PW., Nat Commun 6(), 2015
PMID: 26415554
Draft Genome Sequence of Lactobacillus gorillae Strain KZ01T, Isolated from a Western Lowland Gorilla.
Tsuchida S, Nezuo M, Tsukahara M, Ogura Y, Hayashi T, Ushida K., Genome Announc 3(5), 2015
PMID: 26472838
Quantitative Proteogenomics and the Reconstruction of the Metabolic Pathway in Lactobacillus mucosae LM1.
Pajarillo EA, Kim SH, Lee JY, Valeriano VD, Kang DK., Korean J Food Sci Anim Resour 35(5), 2015
PMID: 26761899
Genomic and Functional Characterization of the Unusual pLOCK 0919 Plasmid Harboring the spaCBA Pili Cluster in Lactobacillus casei LOCK 0919.
Aleksandrzak-Piekarczyk T, Koryszewska-Bagińska A, Grynberg M, Nowak A, Cukrowska B, Kozakova H, Bardowski J., Genome Biol Evol 8(1), 2015
PMID: 26637469
Effect of Lactobacillus brevis ATCC 8287 as a feeding supplement on the performance and immune function of piglets.
Lähteinen T, Lindholm A, Rinttilä T, Junnikkala S, Kant R, Pietilä TE, Levonen K, von Ossowski I, Solano-Aguilar G, Jakava-Viljanen M, Palva A., Vet Immunol Immunopathol 158(1-2), 2014
PMID: 24074625
A comparative pan-genome perspective of niche-adaptable cell-surface protein phenotypes in Lactobacillus rhamnosus.
Kant R, Rintahaka J, Yu X, Sigvart-Mattila P, Paulin L, Mecklin JP, Saarela M, Palva A, von Ossowski I., PLoS One 9(7), 2014
PMID: 25032833
Comparative genomics of Lactobacillus crispatus suggests novel mechanisms for the competitive exclusion of Gardnerella vaginalis.
Ojala T, Kankainen M, Castro J, Cerca N, Edelman S, Westerlund-Wikström B, Paulin L, Holm L, Auvinen P., BMC Genomics 15(), 2014
PMID: 25480015
Comparative genomic and functional analysis of Lactobacillus casei and Lactobacillus rhamnosus strains marketed as probiotics.
Douillard FP, Ribbera A, Järvinen HM, Kant R, Pietilä TE, Randazzo C, Paulin L, Laine PK, Caggia C, von Ossowski I, Reunanen J, Satokari R, Salminen S, Palva A, de Vos WM., Appl Environ Microbiol 79(6), 2013
PMID: 23315726
Comparative genomic and functional analysis of 100 Lactobacillus rhamnosus strains and their comparison with strain GG.
Douillard FP, Ribbera A, Kant R, Pietilä TE, Järvinen HM, Messing M, Randazzo CL, Paulin L, Laine P, Ritari J, Caggia C, Lähteinen T, Brouns SJ, Satokari R, von Ossowski I, Reunanen J, Palva A, de Vos WM., PLoS Genet 9(8), 2013
PMID: 23966868
Comparative genomics analysis of Streptococcus isolates from the human small intestine reveals their adaptation to a highly dynamic ecosystem.
Van den Bogert B, Boekhorst J, Herrmann R, Smid EJ, Zoetendal EG, Kleerebezem M., PLoS One 8(12), 2013
PMID: 24386196
Genome sequence and analysis of Lactobacillus helveticus.
Cremonesi P, Chessa S, Castiglioni B., Front Microbiol 3(), 2012
PMID: 23335916
Genes involved in lactose catabolism and organic acid production during growth of Lactobacillus delbrueckii UFV H2b20 in skimmed milk.
Do Carmo AP, De Oliveira MN, Da Silva DF, Castro SB, Borges AC, De Carvalho AF, De Moraes CA., Benef Microbes 3(1), 2012
PMID: 22348906
The Genus Lactobacillus: A Taxonomic Update.
Salvetti E, Torriani S, Felis GE., Probiotics Antimicrob Proteins 4(4), 2012
PMID: 26782181
Lactic acid bacteria: life after genomics.
Kleerebezem M, de Vos WM., Microb Biotechnol 4(3), 2011
PMID: 21518298
Systems solutions by lactic acid bacteria: from paradigms to practice.
de Vos WM., Microb Cell Fact 10 Suppl 1(), 2011
PMID: 21995776
Genes involved in protein metabolism of the probiotic lactic acid bacterium Lactobacillus delbrueckii UFV H2b20.
Do Carmo AP, da Silva DF, De Oliveira MN, Borges AC, De Carvalho AF, De Moraes CA., Benef Microbes 2(3), 2011
PMID: 21986360

51 References

Daten bereitgestellt von Europe PubMed Central.

Complete genome sequence of the probiotic lactic acid bacterium Lactobacillus acidophilus NCFM.
Altermann E, Russell WM, Azcarate-Peril MA, Barrangou R, Buck BL, McAuliffe O, Souther N, Dobson A, Duong T, Callanan M, Lick S, Hamrick A, Cano R, Klaenhammer TR., Proc. Natl. Acad. Sci. U.S.A. 102(11), 2005
PMID: 15671160
Gapped BLAST and PSI-BLAST: a new generation of protein database search programs.
Altschul SF, Madden TL, Schaffer AA, Zhang J, Zhang Z, Miller W, Lipman DJ., Nucleic Acids Res. 25(17), 1997
PMID: 9254694
Analysis of the genome sequence of Lactobacillus gasseri ATCC 33323 reveals the molecular basis of an autochthonous intestinal organism.
Azcarate-Peril MA, Altermann E, Goh YJ, Tallon R, Sanozky-Dawes RB, Pfeiler EA, O'Flaherty S, Buck BL, Dobson A, Duong T, Miller MJ, Barrangou R, Klaenhammer TR., Appl. Environ. Microbiol. 74(15), 2008
PMID: 18539810
EDGAR: a software framework for the comparative analysis of prokaryotic genomes.
Blom J, Albaum SP, Doppmeier D, Puhler A, Vorholter FJ, Zakrzewski M, Goesmann A., BMC Bioinformatics 10(), 2009
PMID: 19457249
Genome-wide detection and analysis of cell wall-bound proteins with LPxTG-like sorting motifs.
Boekhorst J, de Been MW, Kleerebezem M, Siezen RJ., J. Bacteriol. 187(14), 2005
PMID: 15995208
Identification of Lactobacillus plantarum genes that are induced in the gastrointestinal tract of mice.
Bron PA, Grangette C, Mercenier A, de Vos WM, Kleerebezem M., J. Bacteriol. 186(17), 2004
PMID: 15317777
Lactobacillus plantarum WCFS1 electron transport chains.
Brooijmans RJ, de Vos WM, Hugenholtz J., Appl. Environ. Microbiol. 75(11), 2009
PMID: 19346351
Genome sequence of Lactobacillus helveticus, an organism distinguished by selective gene loss and insertion sequence element expansion.
Callanan M, Kaleta P, O'Callaghan J, O'Sullivan O, Jordan K, McAuliffe O, Sangrador-Vegas A, Slattery L, Fitzgerald GF, Beresford T, Ross RP., J. Bacteriol. 190(2), 2007
PMID: 17993529
Diversity of the genus Lactobacillus revealed by comparative genomics of five species.
Canchaya C, Claesson MJ, Fitzgerald GF, van Sinderen D, O'Toole PW., Microbiology (Reading, Engl.) 152(Pt 11), 2006
PMID: 17074890
The complete genome sequence of the meat-borne lactic acid bacterium Lactobacillus sakei 23K.
Chaillou S, Champomier-Verges MC, Cornet M, Crutz-Le Coq AM, Dudez AM, Martin V, Beaufils S, Darbon-Rongere E, Bossy R, Loux V, Zagorec M., Nat. Biotechnol. 23(12), 2005
PMID: 16273110
The genus Lactobacillus--a genomic basis for understanding its diversity.
Claesson MJ, van Sinderen D, O'Toole PW., FEMS Microbiol. Lett. 269(1), 2007
PMID: 17343688
Lactobacillus phylogenomics--towards a reclassification of the genus.
Claesson MJ, van Sinderen D, O'Toole PW., Int. J. Syst. Evol. Microbiol. 58(Pt 12), 2008
PMID: 19060088
Strong antimicrobial activity of Lactobacillus rhamnosus GG against Salmonella typhimurium is due to accumulation of lactic acid.
De Keersmaecker SC, Verhoeven TL, Desair J, Marchal K, Vanderleyden J, Nagy I., FEMS Microbiol. Lett. 259(1), 2006
PMID: 16684107
Lipotechoic acid in lactobacilli: D-alanine makes the difference.
de Vos WM., Proc. Natl. Acad. Sci. U.S.A. 102(31), 2005
PMID: 16046536
Taxonomy of Lactobacillus and bifidobacteria.
Dellaglio F., Felis G.E.., 2005
Lactobacillus plantarum--survival, functional and potential probiotic properties in the human intestinal tract
Vries MCde, Vaughan EE, Kleerebezem M, Vos WMde., Int. Dairy J. 16(9), 2006
PMID: IND43846856
Locating proteins in the cell using TargetP, SignalP and related tools.
Emanuelsson O, Brunak S, von Heijne G, Nielsen H., Nat Protoc 2(4), 2007
PMID: 17446895

Felsenstein J.., 1995
The complete genome sequence of Lactobacillus bulgaricus reveals extensive and ongoing reductive evolution.
van de Guchte M, Penaud S, Grimaldi C, Barbe V, Bryson K, Nicolas P, Robert C, Oztas S, Mangenot S, Couloux A, Loux V, Dervyn R, Bossy R, Bolotin A, Batto JM, Walunas T, Gibrat JF, Bessieres P, Weissenbach J, Ehrlich SD, Maguin E., Proc. Natl. Acad. Sci. U.S.A. 103(24), 2006
PMID: 16754859
The genus Lactobacillus
Hammes W.P., Vogel R.F.., 1995

Hugenholtz P.., 1998
Comparative genomic analysis of Lactobacillus rhamnosus GG reveals pili containing a human- mucus binding protein.
Kankainen M, Paulin L, Tynkkynen S, von Ossowski I, Reunanen J, Partanen P, Satokari R, Vesterlund S, Hendrickx AP, Lebeer S, De Keersmaecker SC, Vanderleyden J, Hamalainen T, Laukkanen S, Salovuori N, Ritari J, Alatalo E, Korpela R, Mattila-Sandholm T, Lassig A, Hatakka K, Kinnunen KT, Karjalainen H, Saxelin M, Laakso K, Surakka A, Palva A, Salusjarvi T, Auvinen P, de Vos WM., Proc. Natl. Acad. Sci. U.S.A. 106(40), 2009
PMID: 19805152
Complete genome sequence of Lactobacillus plantarum WCFS1.
Kleerebezem M, Boekhorst J, van Kranenburg R, Molenaar D, Kuipers OP, Leer R, Tarchini R, Peters SA, Sandbrink HM, Fiers MW, Stiekema W, Lankhorst RM, Bron PA, Hoffer SM, Groot MN, Kerkhoven R, de Vries M, Ursing B, de Vos WM, Siezen RJ., Proc. Natl. Acad. Sci. U.S.A. 100(4), 2003
PMID: 12566566
The extracellular biology of the lactobacilli.
Kleerebezem M, Hols P, Bernard E, Rolain T, Zhou M, Siezen RJ, Bron PA., FEMS Microbiol. Rev. 34(2), 2010
PMID: 20088967
Involvement of the detoxifying enzyme lactoylglutathione lyase in Streptococcus mutans aciduricity.
Korithoski B, Levesque CM, Cvitkovitch DG., J. Bacteriol. 189(21), 2007
PMID: 17720789
Comparative genomics of the lactic acid bacteria.
Makarova K, Slesarev A, Wolf Y, Sorokin A, Mirkin B, Koonin E, Pavlov A, Pavlova N, Karamychev V, Polouchine N, Shakhova V, Grigoriev I, Lou Y, Rohksar D, Lucas S, Huang K, Goodstein DM, Hawkins T, Plengvidhya V, Welker D, Hughes J, Goh Y, Benson A, Baldwin K, Lee JH, Diaz-Muniz I, Dosti B, Smeianov V, Wechter W, Barabote R, Lorca G, Altermann E, Barrangou R, Ganesan B, Xie Y, Rawsthorne H, Tamir D, Parker C, Breidt F, Broadbent J, Hutkins R, O'Sullivan D, Steele J, Unlu G, Saier M, Klaenhammer T, Richardson P, Kozyavkin S, Weimer B, Mills D., Proc. Natl. Acad. Sci. U.S.A. 103(42), 2006
PMID: 17030793
Convergence in probiotic Lactobacillus gut‐adaptive responses in humans and mice
Marco M.L., de M.C., Wels M., Molenaar D., Mangell P., Ahrne S.., 2010
Complete genome sequence of the probiotic Lactobacillus casei strain BL23.
Maze A, Boel G, Zuniga M, Bourand A, Loux V, Yebra MJ, Monedero V, Correia K, Jacques N, Beaufils S, Poncet S, Joyet P, Milohanic E, Casaregola S, Auffray Y, Perez-Martinez G, Gibrat JF, Zagorec M, Francke C, Hartke A, Deutscher J., J. Bacteriol. 192(10), 2010
PMID: 20348264
Exploring Lactobacillus plantarum genome diversity by using microarrays.
Molenaar D, Bringel F, Schuren FH, de Vos WM, Siezen RJ, Kleerebezem M., J. Bacteriol. 187(17), 2005
PMID: 16109953
Characterization of a prolidase from Lactobacillus delbrueckii subsp. bulgaricus CNRZ 397 with an unusual regulation of biosynthesis.
Morel F, Frot-Coutaz J, Aubel D, Portalier R, Atlan D., Microbiology (Reading, Engl.) 145 ( Pt 2)(), 1999
PMID: 10075426
Comparative genome analysis of Lactobacillus reuteri and Lactobacillus fermentum reveal a genomic island for reuterin and cobalamin production.
Morita H, Toh H, Fukuda S, Horikawa H, Oshima K, Suzuki T, Murakami M, Hisamatsu S, Kato Y, Takizawa T, Fukuoka H, Yoshimura T, Itoh K, O'Sullivan DJ, McKay LL, Ohno H, Kikuchi J, Masaoka T, Hattori M., DNA Res. 15(3), 2008
PMID: 18487258
A catalog of reference genomes from the human microbiome.
Human Microbiome Jumpstart Reference Strains Consortium, Nelson KE, Weinstock GM, Highlander SK, Worley KC, Creasy HH, Wortman JR, Rusch DB, Mitreva M, Sodergren E, Chinwalla AT, Feldgarden M, Gevers D, Haas BJ, Madupu R, Ward DV, Birren BW, Gibbs RA, Methe B, Petrosino JF, Strausberg RL, Sutton GG, White OR, Wilson RK, Durkin S, Giglio MG, Gujja S, Howarth C, Kodira CD, Kyrpides N, Mehta T, Muzny DM, Pearson M, Pepin K, Pati A, Qin X, Yandava C, Zeng Q, Zhang L, Berlin AM, Chen L, Hepburn TA, Johnson J, McCorrison J, Miller J, Minx P, Nusbaum C, Russ C, Sykes SM, Tomlinson CM, Young S, Warren WC, Badger J, Crabtree J, Markowitz VM, Orvis J, Cree A, Ferriera S, Fulton LL, Fulton RS, Gillis M, Hemphill LD, Joshi V, Kovar C, Torralba M, Wetterstrand KA, Abouellleil A, Wollam AM, Buhay CJ, Ding Y, Dugan S, FitzGerald MG, Holder M, Hostetler J, Clifton SW, Allen-Vercoe E, Earl AM, Farmer CN, Liolios K, Surette MG, Xu Q, Pohl C, Wilczek-Boney K, Zhu D., Science 328(5981), 2010
PMID: 20489017
Genome sequence of Lactobacillus crispatus ST1.
Ojala T, Kuparinen V, Koskinen JP, Alatalo E, Holm L, Auvinen P, Edelman S, Westerlund-Wikstrom B, Korhonen TK, Paulin L, Kankainen M., J. Bacteriol. 192(13), 2010
PMID: 20435723
Comparative genomics of lactic acid bacteria reveals a niche-specific gene set.
O'Sullivan O, O'Callaghan J, Sangrador-Vegas A, McAuliffe O, Slattery L, Kaleta P, Callanan M, Fitzgerald GF, Ross RP, Beresford T., BMC Microbiol. 9(), 2009
PMID: 19265535
Taxonomy of lactic acid bacteria
Pot B., Ludwig W., Kersters K., Schleifer K.H.., 1994
The genome sequence of the probiotic intestinal bacterium Lactobacillus johnsonii NCC 533.
Pridmore RD, Berger B, Desiere F, Vilanova D, Barretto C, Pittet AC, Zwahlen MC, Rouvet M, Altermann E, Barrangou R, Mollet B, Mercenier A, Klaenhammer T, Arigoni F, Schell MA., Proc. Natl. Acad. Sci. U.S.A. 101(8), 2004
PMID: 14983040
Probiotic and other functional microbes: from markets to mechanisms.
Saxelin M, Tynkkynen S, Mattila-Sandholm T, de Vos WM., Curr. Opin. Biotechnol. 16(2), 2005
PMID: 15831388
PepR1, a CcpA-like transcription regulator of Lactobacillus delbrueckii subsp. lactis.
Schick J, Weber B, Klein JR, Henrich B., Microbiology (Reading, Engl.) 145 ( Pt 11)(), 1999
PMID: 10589722
A special fondness for lactobacilli.
Tannock GW., Appl. Environ. Microbiol. 70(6), 2004
PMID: 15184111
Engineering metabolic highways in Lactococci and other lactic acid bacteria.
de Vos WM, Hugenholtz J., Trends Biotechnol. 22(2), 2004
PMID: 14757041
Complete genome sequence of Lactobacillus johnsonii FI9785, a competitive exclusion agent against pathogens in poultry.
Wegmann U, Overweg K, Horn N, Goesmann A, Narbad A, Gasson MJ, Shearman C., J. Bacteriol. 191(22), 2009
PMID: 19767436

Wood B.J.B., Holzapfel W.H.., 1995

Wood B.J.B., Warner P.J.., 2003
Quantification of insect genome divergence.
Zdobnov EM, Bork P., Trends Genet. 23(1), 2006
PMID: 17097187
Complete genome sequence of Lactobacillus plantarum JDM1.
Zhang ZY, Liu C, Zhu YZ, Zhong Y, Zhu YQ, Zheng HJ, Zhao GP, Wang SY, Guo XK., J. Bacteriol. 191(15), 2009
PMID: 19465650
LocateP: genome-scale subcellular-location predictor for bacterial proteins.
Zhou M, Boekhorst J, Francke C, Siezen RJ., BMC Bioinformatics 9(), 2008
PMID: 18371216

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