Rose: generating sequence families

Stoye, Jens; Evers, Dirk; Meyer, Folker

Rose: generating sequence families

Stoye J, Evers D, Meyer F (1998)
BIOINFORMATICS 14(2): 157-163.

Zeitschriftenaufsatz | Veröffentlicht | Englisch

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157.pdf

DOI

https://doi.org/10.1093/bioinformatics/14.2.157

URN

urn:nbn:de:0070-pub-16254026

Autor*in

Stoye, Jens^UniBi ; Evers, Dirk; Meyer, Folker

Einrichtung

Technische Fakultät > AG Praktische Informatik
Forschungsschwerpunkt Mathematisierung

Abstract / Bemerkung

Motivation: We present a new probabilistic model of the evolution of RNA-, DNA-, ol protein-like sequences and a software tool, Rose, that implements this model. Guided by an evolutionary tree, a family of related sequences is created from a common ancestor sequence by insertion, deletion and substitution of characters. During this artificial evolutionary process, the 'true' history is logged and the 'correct' multiple sequence alignment is created simultaneously The model also allows for varying rates of mutation within the sequences, making it possible to establish so-called sequence motifs. Results: The data created by Rose are suitable for the evaluation of methods in multiple sequence alignment computation and the prediction of phylogenetic relationships. It can also be useful when reaching courses in or developing models of sequence evolution and in the study of evolutionary processes.

Erscheinungsjahr

1998

Zeitschriftentitel

BIOINFORMATICS

Band

Ausgabe

Seite(n)

157-163

ISSN

1367-4803

eISSN

1460-2059

Page URI

https://pub.uni-bielefeld.de/record/1625402

Zitieren

Stoye J, Evers D, Meyer F. Rose: generating sequence families. BIOINFORMATICS. 1998;14(2):157-163.

Stoye, J., Evers, D., & Meyer, F. (1998). Rose: generating sequence families. BIOINFORMATICS, 14(2), 157-163. https://doi.org/10.1093/bioinformatics/14.2.157

Stoye, Jens, Evers, Dirk, and Meyer, Folker. 1998. “Rose: generating sequence families”. BIOINFORMATICS 14 (2): 157-163.

Stoye, J., Evers, D., and Meyer, F. (1998). Rose: generating sequence families. BIOINFORMATICS 14, 157-163.

Stoye, J., Evers, D., & Meyer, F., 1998. Rose: generating sequence families. BIOINFORMATICS, 14(2), p 157-163.

J. Stoye, D. Evers, and F. Meyer, “Rose: generating sequence families”, BIOINFORMATICS, vol. 14, 1998, pp. 157-163.

Stoye, J., Evers, D., Meyer, F.: Rose: generating sequence families. BIOINFORMATICS. 14, 157-163 (1998).

Stoye, Jens, Evers, Dirk, and Meyer, Folker. “Rose: generating sequence families”. BIOINFORMATICS 14.2 (1998): 157-163.

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2019-09-06T08:48:04Z

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Daten bereitgestellt von European Bioinformatics Institute (EBI)

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