DNA microarray analysis of the nitrogen starvation response of Corynebacterium glutamicum

Silberbach M, Hüser AT, Kalinowski J, Pühler A, Walter B, Kramer R, Burkovski A (2005)
JOURNAL OF BIOTECHNOLOGY 119(4): 357-367.

Zeitschriftenaufsatz | Veröffentlicht | Englisch
 
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DOI
Autor*in
Silberbach, M.; Hüser, Andrea T.; Kalinowski, JörnUniBi; Pühler, AlfredUniBi ; Walter, B.; Kramer, R.; Burkovski, A.
Einrichtung
Fakultät für Biologie
Centrum für Biotechnologie > Arbeitsgruppe J. Kalinowski
Centrum für Biotechnologie > Institut für Genomforschung und Systembiologie
Centrum für Biotechnologie > Arbeitsgruppe A. Pühler
Abstract / Bemerkung
Nitrogen is an essential component of nearly all of the complex macromolecules in a bacterial cell, e.g. proteins, nucleic acids, and cell wall components. Accordingly, most prokaryotes have developed elaborate control mechanisms to provide an optimal supply of nitrogen for cellular metabolism and to cope with situations of nitrogen limitation. In this communication, a global analysis of the Corynebacterium glutamicum nitrogen starvation response by transcriptional profiling using DNA microarrays is presented. Our results show that C. glutamicum reacts to nitrogen starvation with a rearrangement of the cellular transport capacity, changes in metabolic pathways concerning nitrogen assimilation and amino acid biosynthesis, and a decreased capacity for protein synthesis. (C) 2005 Elsevier B.V. All rights reserved.
Stichworte
nitrogen; DNA microarrays; Corynebacterium; nitrogen control; regulation; transcriptome analyses
Erscheinungsjahr
2005
Zeitschriftentitel
JOURNAL OF BIOTECHNOLOGY
Band
119
Ausgabe
4
Seite(n)
357-367
ISSN
0168-1656
Page URI
https://pub.uni-bielefeld.de/record/1601955

Zitieren

Silberbach M, Hüser AT, Kalinowski J, et al. DNA microarray analysis of the nitrogen starvation response of Corynebacterium glutamicum. JOURNAL OF BIOTECHNOLOGY. 2005;119(4):357-367.
Silberbach, M., Hüser, A. T., Kalinowski, J., Pühler, A., Walter, B., Kramer, R., & Burkovski, A. (2005). DNA microarray analysis of the nitrogen starvation response of Corynebacterium glutamicum. JOURNAL OF BIOTECHNOLOGY, 119(4), 357-367. https://doi.org/10.1016/j.jbiotec.2005.04.007
Silberbach, M., Hüser, Andrea T., Kalinowski, Jörn, Pühler, Alfred, Walter, B., Kramer, R., and Burkovski, A. 2005. “DNA microarray analysis of the nitrogen starvation response of Corynebacterium glutamicum”. JOURNAL OF BIOTECHNOLOGY 119 (4): 357-367.
Silberbach, M., Hüser, A. T., Kalinowski, J., Pühler, A., Walter, B., Kramer, R., and Burkovski, A. (2005). DNA microarray analysis of the nitrogen starvation response of Corynebacterium glutamicum. JOURNAL OF BIOTECHNOLOGY 119, 357-367.
Silberbach, M., et al., 2005. DNA microarray analysis of the nitrogen starvation response of Corynebacterium glutamicum. JOURNAL OF BIOTECHNOLOGY, 119(4), p 357-367.
M. Silberbach, et al., “DNA microarray analysis of the nitrogen starvation response of Corynebacterium glutamicum”, JOURNAL OF BIOTECHNOLOGY, vol. 119, 2005, pp. 357-367.
Silberbach, M., Hüser, A.T., Kalinowski, J., Pühler, A., Walter, B., Kramer, R., Burkovski, A.: DNA microarray analysis of the nitrogen starvation response of Corynebacterium glutamicum. JOURNAL OF BIOTECHNOLOGY. 119, 357-367 (2005).
Silberbach, M., Hüser, Andrea T., Kalinowski, Jörn, Pühler, Alfred, Walter, B., Kramer, R., and Burkovski, A. “DNA microarray analysis of the nitrogen starvation response of Corynebacterium glutamicum”. JOURNAL OF BIOTECHNOLOGY 119.4 (2005): 357-367.

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