Motor Recovery of the Affected Hand in Subacute Stroke Correlates with Changes of Contralesional Cortical Hand Motor Representation

Veldema J, Bösl K, Nowak DA (2017)
Neural Plasticity 2017: 6171903.

Zeitschriftenaufsatz | Veröffentlicht | Englisch
 
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Autor*in
Veldema, JitkaUniBi ; Bösl, Kathrin; Nowak, Dennis Alexander
Abstract / Bemerkung
Objective. To investigate the relationship between changes of cortical hand motor representation and motor recovery of the affected hand in subacute stroke.Methods. 17 patients with motor impairment of the affected hand were enrolled in an in-patient neurological rehabilitation program. Hand motor function tests (Wolf Motor Function Test, Action Research Arm Test) and neurophysiological evaluations (resting motor threshold, motor evoked potentials, motor map area size, motor map area volume, and motor map area location) were obtained from both hands and hemispheres at baseline and two, four, and six weeks of in-patient rehabilitation.Results. There was a wide spectrum of hand motor impairment at baseline and hand motor recovery over time. Hand motor function and recovery correlated significantly with (i) reduction of cortical excitability, (ii) reduction in size and volume of cortical hand motor representation, and (iii) a medial and anterior shift of the center of gravity of cortical hand motor representation within the contralesional hemisphere.Conclusion. Recovery of motor function of the affected hand after stroke is accompanied by definite changes in excitability, size, volume, and location of hand motor representation over the contralesional primary motor cortex. These measures may serve as surrogate markers for the outcome of hand motor rehabilitation after stroke.
Erscheinungsjahr
2017
Zeitschriftentitel
Neural Plasticity
Band
2017
Art.-Nr.
6171903
ISSN
2090-5904
eISSN
1687-5443
Page URI
https://pub.uni-bielefeld.de/record/2960931

Zitieren

Veldema J, Bösl K, Nowak DA. Motor Recovery of the Affected Hand in Subacute Stroke Correlates with Changes of Contralesional Cortical Hand Motor Representation. Neural Plasticity. 2017;2017: 6171903.
Veldema, J., Bösl, K., & Nowak, D. A. (2017). Motor Recovery of the Affected Hand in Subacute Stroke Correlates with Changes of Contralesional Cortical Hand Motor Representation. Neural Plasticity, 2017, 6171903. https://doi.org/10.1155/2017/6171903
Veldema, J., Bösl, K., and Nowak, D. A. (2017). Motor Recovery of the Affected Hand in Subacute Stroke Correlates with Changes of Contralesional Cortical Hand Motor Representation. Neural Plasticity 2017:6171903.
Veldema, J., Bösl, K., & Nowak, D.A., 2017. Motor Recovery of the Affected Hand in Subacute Stroke Correlates with Changes of Contralesional Cortical Hand Motor Representation. Neural Plasticity, 2017: 6171903.
J. Veldema, K. Bösl, and D.A. Nowak, “Motor Recovery of the Affected Hand in Subacute Stroke Correlates with Changes of Contralesional Cortical Hand Motor Representation”, Neural Plasticity, vol. 2017, 2017, : 6171903.
Veldema, J., Bösl, K., Nowak, D.A.: Motor Recovery of the Affected Hand in Subacute Stroke Correlates with Changes of Contralesional Cortical Hand Motor Representation. Neural Plasticity. 2017, : 6171903 (2017).
Veldema, Jitka, Bösl, Kathrin, and Nowak, Dennis Alexander. “Motor Recovery of the Affected Hand in Subacute Stroke Correlates with Changes of Contralesional Cortical Hand Motor Representation”. Neural Plasticity 2017 (2017): 6171903.

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