MOG antibody-associated encephalitis secondary to Covid-19: case report

Durovic E, Bien C, Bien C, Isenmann S (2021)
BMC Neurology 21(1): 414.

Zeitschriftenaufsatz | Veröffentlicht | Englisch
 
Download
Es wurden keine Dateien hochgeladen. Nur Publikationsnachweis!
Autor*in
Durovic, Ervin; Bien, Corinna; Bien, ChristianUniBi; Isenmann, Stefan
Abstract / Bemerkung
BACKGROUND: While Covid-19 predominantly affects the respiratory system, neurological manifestations including encephalitis occur in some patients, possibly affecting the course and outcome of the disease. Here, we describe a unique case of a young man with Covid-19 and transient MOG-positive encephalitis, with a benign course.; CASE PRESENTATION: A 22-year-old male, with PCR confirmed Covid-19 infection was admitted because of persistent headache. The clinical examination was normal. Neuropsychological testing revealed distinct executive deficits. Brain MRI and cerebrospinal fluid (CSF) analysis were suggestive for encephalitis. Further laboratory examination revealed a serum MOG antibody titre. The headache improved with analgetic treatment and i.v. methylprednisolone. Consequently, the MOG antibody titer decreased and MRI lesions were resolving. The patient made a full recovery, with no signs of deterioration over the following months.; CONCLUSIONS: Covid-19 manifestations in the CNS include encephalitis with variable course and prognosis. This case highlights a possible association between inflammation due to COVID-19 and transient secondary autoimmunity with transient MOG antibodies and atypical clinical presentation. © 2021. The Author(s).
Erscheinungsjahr
2021
Zeitschriftentitel
BMC Neurology
Band
21
Ausgabe
1
Art.-Nr.
414
eISSN
1471-2377
Page URI
https://pub.uni-bielefeld.de/record/2958742

Zitieren

Durovic E, Bien C, Bien C, Isenmann S. MOG antibody-associated encephalitis secondary to Covid-19: case report. BMC Neurology. 2021;21(1): 414.
Durovic, E., Bien, C., Bien, C., & Isenmann, S. (2021). MOG antibody-associated encephalitis secondary to Covid-19: case report. BMC Neurology, 21(1), 414. https://doi.org/10.1186/s12883-021-02449-5
Durovic, E., Bien, C., Bien, C., and Isenmann, S. (2021). MOG antibody-associated encephalitis secondary to Covid-19: case report. BMC Neurology 21:414.
Durovic, E., et al., 2021. MOG antibody-associated encephalitis secondary to Covid-19: case report. BMC Neurology, 21(1): 414.
E. Durovic, et al., “MOG antibody-associated encephalitis secondary to Covid-19: case report”, BMC Neurology, vol. 21, 2021, : 414.
Durovic, E., Bien, C., Bien, C., Isenmann, S.: MOG antibody-associated encephalitis secondary to Covid-19: case report. BMC Neurology. 21, : 414 (2021).
Durovic, Ervin, Bien, Corinna, Bien, Christian, and Isenmann, Stefan. “MOG antibody-associated encephalitis secondary to Covid-19: case report”. BMC Neurology 21.1 (2021): 414.

Export

Markieren/ Markierung löschen
Markierte Publikationen

Open Data PUB

Web of Science

Dieser Datensatz im Web of Science®

Quellen

PMID: 34706651
PubMed | Europe PMC

Suchen in

Google Scholar