Relationship between subtypes and symptoms of ADHD, insomnia, and nightmares in connection with quality of life in children
Grünwald J, Schlarb A (2017)
Neuropsychiatric Disease and Treatment 13: 2341-2350.
Zeitschriftenaufsatz
| Veröffentlicht | Englisch
Download
Autor*in
Grünwald, Julia;
Schlarb, AngelikaUniBi
Abstract / Bemerkung
**Objectives:** This study examined the links between sleep disorders and subtypes of attention deficit-hyperactivity disorder (ADHD-inattention, ADHD-combined, ADHD-hyperactive/impulsive) in childhood. We set up a hypothetical model linking different symptoms of both disorders to construct the underlying and shared pathways. By examining a sample of children with ADHD we firstly tested parts of the model.
**Methods:** A total of 72 children with symptoms of ADHD (aged 6–13 years; 79.2% boys) were diagnosed according to the Diagnostic and Statistical Manual of Mental Disorders, fifth edition and the International Classification of Sleep Disorders, third edition in regards to ADHD and sleep disorders via standardized parent-rated questionnaires. Additionally, quality of life (QoL) was assessed. Overall, 46 children fulfilled the criteria of ADHD and were medication-naive.
**Results:** On average, the whole sample had clinically elevated total scores of the Children’s Sleep Habits Questionnaire in the validated German version (CSHQ-DE), indicating an increased prevalence of sleep disorders in children with ADHD. In accordance to our hypothetical model, children with primarily hyperactive–impulsive ADHD showed the highest CSHQ-DE scores. Moreover, we found a high impact for insomnia in this subgroup and a high comorbid load for the mutual occurrence of insomnia and nightmares. Furthermore, QoL was reduced in our whole sample, and again intensified in children with comorbid insomnia and nightmares.
**Conclusion:** We verified an elevated occurrence of sleep disorders in children with ADHD and were able to link them to specific subtypes of ADHD. These results were in line with our hypothetical model. Moreover, we found a clinically reduced QoL in mean for the whole sample, indicating the strong impact of ADHD in the lives of affected children, even intensified if children exhibited comorbid insomnia and nightmares. These results should be kept in mind regarding the treatment and therapy of this subgroup of children. Specific treatment strategies should be considered for these children.
**Methods:** A total of 72 children with symptoms of ADHD (aged 6–13 years; 79.2% boys) were diagnosed according to the Diagnostic and Statistical Manual of Mental Disorders, fifth edition and the International Classification of Sleep Disorders, third edition in regards to ADHD and sleep disorders via standardized parent-rated questionnaires. Additionally, quality of life (QoL) was assessed. Overall, 46 children fulfilled the criteria of ADHD and were medication-naive.
**Results:** On average, the whole sample had clinically elevated total scores of the Children’s Sleep Habits Questionnaire in the validated German version (CSHQ-DE), indicating an increased prevalence of sleep disorders in children with ADHD. In accordance to our hypothetical model, children with primarily hyperactive–impulsive ADHD showed the highest CSHQ-DE scores. Moreover, we found a high impact for insomnia in this subgroup and a high comorbid load for the mutual occurrence of insomnia and nightmares. Furthermore, QoL was reduced in our whole sample, and again intensified in children with comorbid insomnia and nightmares.
**Conclusion:** We verified an elevated occurrence of sleep disorders in children with ADHD and were able to link them to specific subtypes of ADHD. These results were in line with our hypothetical model. Moreover, we found a clinically reduced QoL in mean for the whole sample, indicating the strong impact of ADHD in the lives of affected children, even intensified if children exhibited comorbid insomnia and nightmares. These results should be kept in mind regarding the treatment and therapy of this subgroup of children. Specific treatment strategies should be considered for these children.
Stichworte
impulsivity;
hyperactivity;
inattention;
sleep disorders;
childhood
Erscheinungsjahr
2017
Zeitschriftentitel
Neuropsychiatric Disease and Treatment
Band
13
Seite(n)
2341-2350
Urheberrecht / Lizenzen
ISSN
1178-2021
Finanzierungs-Informationen
Open-Access-Publikationskosten wurden durch die Deutsche Forschungsgemeinschaft und die Universität Bielefeld gefördert.
Page URI
https://pub.uni-bielefeld.de/record/2913652
Zitieren
Grünwald J, Schlarb A. Relationship between subtypes and symptoms of ADHD, insomnia, and nightmares in connection with quality of life in children. Neuropsychiatric Disease and Treatment. 2017;13:2341-2350.
Grünwald, J., & Schlarb, A. (2017). Relationship between subtypes and symptoms of ADHD, insomnia, and nightmares in connection with quality of life in children. Neuropsychiatric Disease and Treatment, 13, 2341-2350. doi:10.2147/ndt.s118076
Grünwald, Julia, and Schlarb, Angelika. 2017. “Relationship between subtypes and symptoms of ADHD, insomnia, and nightmares in connection with quality of life in children”. Neuropsychiatric Disease and Treatment 13: 2341-2350.
Grünwald, J., and Schlarb, A. (2017). Relationship between subtypes and symptoms of ADHD, insomnia, and nightmares in connection with quality of life in children. Neuropsychiatric Disease and Treatment 13, 2341-2350.
Grünwald, J., & Schlarb, A., 2017. Relationship between subtypes and symptoms of ADHD, insomnia, and nightmares in connection with quality of life in children. Neuropsychiatric Disease and Treatment, 13, p 2341-2350.
J. Grünwald and A. Schlarb, “Relationship between subtypes and symptoms of ADHD, insomnia, and nightmares in connection with quality of life in children”, Neuropsychiatric Disease and Treatment, vol. 13, 2017, pp. 2341-2350.
Grünwald, J., Schlarb, A.: Relationship between subtypes and symptoms of ADHD, insomnia, and nightmares in connection with quality of life in children. Neuropsychiatric Disease and Treatment. 13, 2341-2350 (2017).
Grünwald, Julia, and Schlarb, Angelika. “Relationship between subtypes and symptoms of ADHD, insomnia, and nightmares in connection with quality of life in children”. Neuropsychiatric Disease and Treatment 13 (2017): 2341-2350.
Alle Dateien verfügbar unter der/den folgenden Lizenz(en):
Creative Commons Namensnennung-Nicht kommerziell 3.0 Unported (CC BY-NC 3.0):
Volltext(e)
Access Level
Open Access
Zuletzt Hochgeladen
2019-09-06T09:18:51Z
MD5 Prüfsumme
5069d6bca75e8cd6122f273224b8a9fb
Daten bereitgestellt von European Bioinformatics Institute (EBI)
2 Zitationen in Europe PMC
Daten bereitgestellt von Europe PubMed Central.
[Sleep and cognition in children and adolescents].
Prehn-Kristensen A, Göder R., Z Kinder Jugendpsychiatr Psychother 46(5), 2018
PMID: 30141742
Prehn-Kristensen A, Göder R., Z Kinder Jugendpsychiatr Psychother 46(5), 2018
PMID: 30141742
Sleep disorders in patients with ADHD: impact and management challenges.
Wajszilber D, Santiseban JA, Gruber R., Nat Sci Sleep 10(), 2018
PMID: 30588139
Wajszilber D, Santiseban JA, Gruber R., Nat Sci Sleep 10(), 2018
PMID: 30588139
54 References
Daten bereitgestellt von Europe PubMed Central.
[Attention deficit/hyperactivity disorders among three-to-six-year-olds treated in medical practices--a national survey].
Breuer D, Dopfner M., Z Kinder Jugendpsychiatr Psychother 34(5), 2006
PMID: 16981156
Breuer D, Dopfner M., Z Kinder Jugendpsychiatr Psychother 34(5), 2006
PMID: 16981156
The worldwide prevalence of ADHD: a systematic review and metaregression analysis.
Polanczyk G, de Lima MS, Horta BL, Biederman J, Rohde LA., Am J Psychiatry 164(6), 2007
PMID: 17541055
Polanczyk G, de Lima MS, Horta BL, Biederman J, Rohde LA., Am J Psychiatry 164(6), 2007
PMID: 17541055
The prevalence of DSM-IV attention-deficit/hyperactivity disorder: a meta-analytic review.
Willcutt EG., Neurotherapeutics 9(3), 2012
PMID: 22976615
Willcutt EG., Neurotherapeutics 9(3), 2012
PMID: 22976615
Psychosocial treatments for ADHD in teens and adults: a practice-friendly review.
Murphy K., J Clin Psychol 61(5), 2005
PMID: 15723366
Murphy K., J Clin Psychol 61(5), 2005
PMID: 15723366
Entwicklungspsychopathologie der ADHS. [Developmental Psychopathology of ADHD]
Schmidt S, Petermann F., 2008
Schmidt S, Petermann F., 2008
Practice parameter for the assessment and treatment of children and adolescents with attention-deficit/hyperactivity disorder.
Pliszka S; AACAP Work Group on Quality Issues., J Am Acad Child Adolesc Psychiatry 46(7), 2007
PMID: 17581453
Pliszka S; AACAP Work Group on Quality Issues., J Am Acad Child Adolesc Psychiatry 46(7), 2007
PMID: 17581453
AUTHOR UNKNOWN, 2013
Co-existing disorders in ADHD -- implications for diagnosis and intervention.
Gillberg C, Gillberg IC, Rasmussen P, Kadesjo B, Soderstrom H, Rastam M, Johnson M, Rothenberger A, Niklasson L., Eur Child Adolesc Psychiatry 13 Suppl 1(), 2004
PMID: 15322959
Gillberg C, Gillberg IC, Rasmussen P, Kadesjo B, Soderstrom H, Rastam M, Johnson M, Rothenberger A, Niklasson L., Eur Child Adolesc Psychiatry 13 Suppl 1(), 2004
PMID: 15322959
Comorbidity in ADHD: implications for research, practice, and DSM-V.
Jensen PS, Martin D, Cantwell DP., J Am Acad Child Adolesc Psychiatry 36(8), 1997
PMID: 9256586
Jensen PS, Martin D, Cantwell DP., J Am Acad Child Adolesc Psychiatry 36(8), 1997
PMID: 9256586
Sleep problems and their effect in ADHD.
Kirov R, Brand S., Expert Rev Neurother 14(3), 2014
PMID: 24491141
Kirov R, Brand S., Expert Rev Neurother 14(3), 2014
PMID: 24491141
Predictors of persistence and remission of ADHD into adolescence: results from a four-year prospective follow-up study.
Biederman J, Faraone S, Milberger S, Curtis S, Chen L, Marrs A, Ouellette C, Moore P, Spencer T., J Am Acad Child Adolesc Psychiatry 35(3), 1996
PMID: 8714323
Biederman J, Faraone S, Milberger S, Curtis S, Chen L, Marrs A, Ouellette C, Moore P, Spencer T., J Am Acad Child Adolesc Psychiatry 35(3), 1996
PMID: 8714323
Sleep in children with attention-deficit/hyperactivity disorder: meta-analysis of subjective and objective studies.
Cortese S, Faraone SV, Konofal E, Lecendreux M., J Am Acad Child Adolesc Psychiatry 48(9), 2009
PMID: 19625983
Cortese S, Faraone SV, Konofal E, Lecendreux M., J Am Acad Child Adolesc Psychiatry 48(9), 2009
PMID: 19625983
Sleep problems of school-aged children: a complementary view.
Paavonen EJ, Aronen ET, Moilanen I, Piha J, Rasanen E, Tamminen T, Almqvist F., Acta Paediatr. 89(2), 2000
PMID: 10709895
Paavonen EJ, Aronen ET, Moilanen I, Piha J, Rasanen E, Tamminen T, Almqvist F., Acta Paediatr. 89(2), 2000
PMID: 10709895
Comorbidity and confounding factors in attention-deficit/hyperactivity disorder and sleep disorders in children.
Jan YW, Yang CM, Huang YS., Psychol Res Behav Manag 4(), 2011
PMID: 22114544
Jan YW, Yang CM, Huang YS., Psychol Res Behav Manag 4(), 2011
PMID: 22114544
The use of actigraphy in the monitoring of sleep and activity in ADHD: A meta-analysis.
De Crescenzo F, Licchelli S, Ciabattini M, Menghini D, Armando M, Alfieri P, Mazzone L, Pontrelli G, Livadiotti S, Foti F, Quested D, Vicari S., Sleep Med Rev 26(), 2015
PMID: 26163053
De Crescenzo F, Licchelli S, Ciabattini M, Menghini D, Armando M, Alfieri P, Mazzone L, Pontrelli G, Livadiotti S, Foti F, Quested D, Vicari S., Sleep Med Rev 26(), 2015
PMID: 26163053
Subjective and objective measures of sleep in children with attention-deficit/hyperactivity disorder.
Owens J, Sangal RB, Sutton VK, Bakken R, Allen AJ, Kelsey D., Sleep Med. 10(4), 2008
PMID: 18693137
Owens J, Sangal RB, Sutton VK, Bakken R, Allen AJ, Kelsey D., Sleep Med. 10(4), 2008
PMID: 18693137
REM-sleep alterations in children with co-existence of tic disorders and attention-deficit/hyperactivity disorder: impact of hypermotor symptoms
Kirov R, Banaschweski T, Uebel H, Kinkelbur J, Rothenberger A., 2007
Kirov R, Banaschweski T, Uebel H, Kinkelbur J, Rothenberger A., 2007
REM-sleep changes in children with attention-deficit/hyperactivity disorder: methodologic and neurobiologic considerations
Kirov R, Pillar G, Rothenberger A., 2004
Kirov R, Pillar G, Rothenberger A., 2004
Sleep in children with attention-deficit/hyperactivity disorder (ADHD) before and after 6-month treatment with methylphenidate: a pilot study.
Vigliano P, Galloni GB, Bagnasco I, Delia G, Moletto A, Mana M, Cortese S., Eur. J. Pediatr. 175(5), 2016
PMID: 26833051
Vigliano P, Galloni GB, Bagnasco I, Delia G, Moletto A, Mana M, Cortese S., Eur. J. Pediatr. 175(5), 2016
PMID: 26833051
Actigraphy and parental ratings of sleep in children with attention-deficit/hyperactivity disorder (ADHD).
Corkum P, Tannock R, Moldofsky H, Hogg-Johnson S, Humphries T., Sleep 24(3), 2001
PMID: 11322713
Corkum P, Tannock R, Moldofsky H, Hogg-Johnson S, Humphries T., Sleep 24(3), 2001
PMID: 11322713
Subtypes of ADHD and their association with sleep disturbances in children
Wagner J, Schlarb AA., 2012
Wagner J, Schlarb AA., 2012
Sleep problems and disorders among adolescents with persistent and subthreshold attention-deficit/hyperactivity disorders.
Gau SS, Chiang HL., Sleep 32(5), 2009
PMID: 19480234
Gau SS, Chiang HL., Sleep 32(5), 2009
PMID: 19480234
Towards a cognitive-behavioral model of PTSD in children and adolescents.
Meiser-Stedman R., Clin Child Fam Psychol Rev 5(4), 2002
PMID: 12495267
Meiser-Stedman R., Clin Child Fam Psychol Rev 5(4), 2002
PMID: 12495267
Parents' reports of disturbed sleep in 5-7-year-old Swedish children.
Smedje H, Broman JE, Hetta J., Acta Paediatr. 88(8), 1999
PMID: 10503686
Smedje H, Broman JE, Hetta J., Acta Paediatr. 88(8), 1999
PMID: 10503686
Sleep problems and poor academic performance in primary school children
Wiechers S, Schlarb AA, Urschitz MS, Eggebrecht E, Schlaud M, Poets CF., 2011
Wiechers S, Schlarb AA, Urschitz MS, Eggebrecht E, Schlaud M, Poets CF., 2011
Association between symptoms and subtypes of attention-deficit hyperactivity disorder and sleep problems/disorders.
Chiang HL, Gau SS, Ni HC, Chiu YN, Shang CY, Wu YY, Lin LY, Tai YM, Soong WT., J Sleep Res 19(4), 2010
PMID: 20408926
Chiang HL, Gau SS, Ni HC, Chiu YN, Shang CY, Wu YY, Lin LY, Tai YM, Soong WT., J Sleep Res 19(4), 2010
PMID: 20408926
Frequent nightmares in children: familial aggregation and associations with parent-reported behavioral and mood problems.
Li SX, Yu MW, Lam SP, Zhang J, Li AM, Lai KY, Wing YK., Sleep 34(4), 2011
PMID: 21461327
Li SX, Yu MW, Lam SP, Zhang J, Li AM, Lai KY, Wing YK., Sleep 34(4), 2011
PMID: 21461327
Nightmares as predictors of psychiatric disorders in adolescence
Kirov R, Brand S., 2011
Kirov R, Brand S., 2011
Variation in common preschool sleep problems as an early predictor for depression and anxiety symptom severity across time.
Whalen DJ, Gilbert KE, Barch DM, Luby JL, Belden AC., J Child Psychol Psychiatry 58(2), 2016
PMID: 27616560
Whalen DJ, Gilbert KE, Barch DM, Luby JL, Belden AC., J Child Psychol Psychiatry 58(2), 2016
PMID: 27616560
Sleep-related problems among children and adolescents with anxiety disorders.
Alfano CA, Ginsburg GS, Kingery JN., J Am Acad Child Adolesc Psychiatry 46(2), 2007
PMID: 17242626
Alfano CA, Ginsburg GS, Kingery JN., J Am Acad Child Adolesc Psychiatry 46(2), 2007
PMID: 17242626
Sleep problems and their relation to cognitive factors, anxiety, and depressive symptoms in children and adolescents.
Alfano CA, Zakem AH, Costa NM, Taylor LK, Weems CF., Depress Anxiety 26(6), 2009
PMID: 19067319
Alfano CA, Zakem AH, Costa NM, Taylor LK, Weems CF., Depress Anxiety 26(6), 2009
PMID: 19067319
The association between anxiety symptoms and sleep in school-aged children: a combined insight from the children’s sleep habits questionnaire and actigraphy
Fletcher FE, Conduit R, Foster-Owens MD, Rinehart NJ, Rajaratnam SMW, Cornish KM., 2016
Fletcher FE, Conduit R, Foster-Owens MD, Rinehart NJ, Rajaratnam SMW, Cornish KM., 2016
Instability of sleep patterns in children with attention-deficit/hyperactivity disorder.
Gruber R, Sadeh A, Raviv A., J Am Acad Child Adolesc Psychiatry 39(4), 2000
PMID: 10761352
Gruber R, Sadeh A, Raviv A., J Am Acad Child Adolesc Psychiatry 39(4), 2000
PMID: 10761352
Disturbed sleep in attention-deficit hyperactivity disorder (ADHD) is not a question of psychiatric comorbidity or ADHD presentation.
Virring A, Lambek R, Thomsen PH, Moller LR, Jennum PJ., J Sleep Res 25(3), 2016
PMID: 26762193
Virring A, Lambek R, Thomsen PH, Moller LR, Jennum PJ., J Sleep Res 25(3), 2016
PMID: 26762193
Relationship between quality of life and psychopathological profile: data from an observational study in children with ADHD
Becker A, Roessner V, Breuer D, Döpfner M, Rothenberger A., 2011
Becker A, Roessner V, Breuer D, Döpfner M, Rothenberger A., 2011
REM sleep and dreaming functions beyond reductionism.
Kirov R., Behav Brain Sci 36(6), 2013
PMID: 24304763
Kirov R., Behav Brain Sci 36(6), 2013
PMID: 24304763
Comorbidity of empirically based syndromes in matched general population and clinical samples.
McConaughy SH, Achenbach TM., J Child Psychol Psychiatry 35(6), 1994
PMID: 7995848
McConaughy SH, Achenbach TM., J Child Psychol Psychiatry 35(6), 1994
PMID: 7995848
Worse quality of life for children with newly diagnosed attention-deficit/hyperactivity disorder, compared with asthmatic and healthy children.
Escobar R, Soutullo CA, Hervas A, Gastaminza X, Polavieja P, Gilaberte I., Pediatrics 116(3), 2005
PMID: 16140679
Escobar R, Soutullo CA, Hervas A, Gastaminza X, Polavieja P, Gilaberte I., Pediatrics 116(3), 2005
PMID: 16140679
Health-related quality of life in children and adolescents who have a diagnosis of attention-deficit/hyperactivity disorder.
Klassen AF, Miller A, Fine S., Pediatrics 114(5), 2004
PMID: 15520087
Klassen AF, Miller A, Fine S., Pediatrics 114(5), 2004
PMID: 15520087
Petermann F, Petermann UH., 2007
Döpfner M, Görtz-Dorten A., 2008
Validation and psychometric properties of the German version of the Children’s Sleep Habits Questionnaire (CSHQ-DE)
Schlarb AA, Schwerdtle B, Hautzinger M., 2010
Schlarb AA, Schwerdtle B, Hautzinger M., 2010
Einführung und Anleitung zur Handauswertung 2
AUTHOR UNKNOWN, 1998
AUTHOR UNKNOWN, 1998
AUTHOR UNKNOWN, 2005
Gesundheitsbezogene Lebensqualität von Kindern und Jugendlichen in Deutschland. [Health-related Quality of Life of Children and Adolescents in Germany. Norm Data from the German Health Interview and Examination (KiGGS)]
Ravens-Sieberer U, Ellert U, Erhart M., 2007
Ravens-Sieberer U, Ellert U, Erhart M., 2007
A new diagnostic tool for children with sleep disorders
Schwerdtle B, Kanis J, Kahl L, Kübler A, Schlarb AA., 2013
Schwerdtle B, Kanis J, Kahl L, Kübler A, Schlarb AA., 2013
The children’s sleep comic – psychometrics of a self-rating for childhood insomnia
Schwerdtle B, Kanis J, Kübler A, Schlarb AA., 2015
Schwerdtle B, Kanis J, Kübler A, Schlarb AA., 2015
Validity of child sleep diary questionnaire among junior high school children.
Gaina A, Sekine M, Chen X, Hamanishi S, Kagamimori S., J Epidemiol 14(1), 2004
PMID: 15065685
Gaina A, Sekine M, Chen X, Hamanishi S, Kagamimori S., J Epidemiol 14(1), 2004
PMID: 15065685
Behavior, cognition, and quality of life after adenotonsillectomy for pediatric sleep-disordered breathing: summary of the literature.
Garetz SL., Otolaryngol Head Neck Surg 138(1 Suppl), 2008
PMID: 18164375
Garetz SL., Otolaryngol Head Neck Surg 138(1 Suppl), 2008
PMID: 18164375
Sleep disordered breathing: effects of adenotonsillectomy on behaviour and psychological functioning.
Ali NJ, Pitson D, Stradling JR., Eur. J. Pediatr. 155(1), 1996
PMID: 8750813
Ali NJ, Pitson D, Stradling JR., Eur. J. Pediatr. 155(1), 1996
PMID: 8750813
Inattention, hyperactivity, and symptoms of sleep-disordered breathing.
Chervin RD, Archbold KH, Dillon JE, Panahi P, Pituch KJ, Dahl RE, Guilleminault C., Pediatrics 109(3), 2002
PMID: 11875140
Chervin RD, Archbold KH, Dillon JE, Panahi P, Pituch KJ, Dahl RE, Guilleminault C., Pediatrics 109(3), 2002
PMID: 11875140
Validierung und psychometrische Eigenschaften der deutschen Version des Sleep Self Report (SSR-DE). [Validation and psychometric properties of the German Version of the Sleep Self Report (SSR-DE)]. Ein Selbstbeurteilungsinstrument zur Erfassung von Schlafstörungen für Kinder von 7–12 Jahren
Schwerdtle B, Roeser K, Kübler A, Schlarb AA., 2010
Schwerdtle B, Roeser K, Kübler A, Schlarb AA., 2010
Export
Markieren/ Markierung löschen
Markierte Publikationen
Web of Science
Dieser Datensatz im Web of Science®Quellen
PMID: 28919767
PubMed | Europe PMC
Suchen in