The mucin MUC1 modulates the tumor immunological microenvironment through engagement of the lectin Siglec-9
Beatson R, Tajadura-Ortega V, Achkova D, Picco G, Tsourouktsoglou T-D, Klausing S, Hillier M, Maher J, Noll T, Crocker PR, Taylor-Papadimitriou J, et al. (2016)
Nature Immunology 17(11): 1273-1281.
Zeitschriftenaufsatz
| Veröffentlicht | Englisch
Download
Es wurden keine Dateien hochgeladen. Nur Publikationsnachweis!
Autor*in
Beatson, Richard;
Tajadura-Ortega, Virginia;
Achkova, Daniela;
Picco, Gianfranco;
Tsourouktsoglou, Theodora-Dorita;
Klausing, SandraUniBi;
Hillier, Matthew;
Maher, John;
Noll, ThomasUniBi ;
Crocker, Paul R;
Taylor-Papadimitriou, Joyce;
Burchell, Joy M
Einrichtung
Erscheinungsjahr
2016
Zeitschriftentitel
Nature Immunology
Band
17
Ausgabe
11
Seite(n)
1273-1281
ISSN
1529-2908, 1529-2916
Page URI
https://pub.uni-bielefeld.de/record/2906641
Zitieren
Beatson R, Tajadura-Ortega V, Achkova D, et al. The mucin MUC1 modulates the tumor immunological microenvironment through engagement of the lectin Siglec-9. Nature Immunology. 2016;17(11):1273-1281.
Beatson, R., Tajadura-Ortega, V., Achkova, D., Picco, G., Tsourouktsoglou, T. - D., Klausing, S., Hillier, M., et al. (2016). The mucin MUC1 modulates the tumor immunological microenvironment through engagement of the lectin Siglec-9. Nature Immunology, 17(11), 1273-1281. doi:10.1038/ni.3552
Beatson, Richard, Tajadura-Ortega, Virginia, Achkova, Daniela, Picco, Gianfranco, Tsourouktsoglou, Theodora-Dorita, Klausing, Sandra, Hillier, Matthew, et al. 2016. “The mucin MUC1 modulates the tumor immunological microenvironment through engagement of the lectin Siglec-9”. Nature Immunology 17 (11): 1273-1281.
Beatson, R., Tajadura-Ortega, V., Achkova, D., Picco, G., Tsourouktsoglou, T. - D., Klausing, S., Hillier, M., Maher, J., Noll, T., Crocker, P. R., et al. (2016). The mucin MUC1 modulates the tumor immunological microenvironment through engagement of the lectin Siglec-9. Nature Immunology 17, 1273-1281.
Beatson, R., et al., 2016. The mucin MUC1 modulates the tumor immunological microenvironment through engagement of the lectin Siglec-9. Nature Immunology, 17(11), p 1273-1281.
R. Beatson, et al., “The mucin MUC1 modulates the tumor immunological microenvironment through engagement of the lectin Siglec-9”, Nature Immunology, vol. 17, 2016, pp. 1273-1281.
Beatson, R., Tajadura-Ortega, V., Achkova, D., Picco, G., Tsourouktsoglou, T.-D., Klausing, S., Hillier, M., Maher, J., Noll, T., Crocker, P.R., Taylor-Papadimitriou, J., Burchell, J.M.: The mucin MUC1 modulates the tumor immunological microenvironment through engagement of the lectin Siglec-9. Nature Immunology. 17, 1273-1281 (2016).
Beatson, Richard, Tajadura-Ortega, Virginia, Achkova, Daniela, Picco, Gianfranco, Tsourouktsoglou, Theodora-Dorita, Klausing, Sandra, Hillier, Matthew, Maher, John, Noll, Thomas, Crocker, Paul R, Taylor-Papadimitriou, Joyce, and Burchell, Joy M. “The mucin MUC1 modulates the tumor immunological microenvironment through engagement of the lectin Siglec-9”. Nature Immunology 17.11 (2016): 1273-1281.
Daten bereitgestellt von European Bioinformatics Institute (EBI)
26 Zitationen in Europe PMC
Daten bereitgestellt von Europe PubMed Central.
Expression profiling of immune inhibitory Siglecs and their ligands in patients with glioma.
Santegoets KCM, Gielen PR, Büll C, Schulte BM, Kers-Rebel ED, Küsters B, Bossman SAJFH, Ter Laan M, Wesseling P, Adema GJ., Cancer Immunol Immunother 68(6), 2019
PMID: 30953118
Santegoets KCM, Gielen PR, Büll C, Schulte BM, Kers-Rebel ED, Küsters B, Bossman SAJFH, Ter Laan M, Wesseling P, Adema GJ., Cancer Immunol Immunother 68(6), 2019
PMID: 30953118
Sugar Free: Novel Immunotherapeutic Approaches Targeting Siglecs and Sialic Acids to Enhance Natural Killer Cell Cytotoxicity Against Cancer.
Daly J, Carlsten M, O'Dwyer M., Front Immunol 10(), 2019
PMID: 31143186
Daly J, Carlsten M, O'Dwyer M., Front Immunol 10(), 2019
PMID: 31143186
Protein Glycosylation and Tumor Microenvironment Alterations Driving Cancer Hallmarks.
Peixoto A, Relvas-Santos M, Azevedo R, Santos LL, Ferreira JA., Front Oncol 9(), 2019
PMID: 31157165
Peixoto A, Relvas-Santos M, Azevedo R, Santos LL, Ferreira JA., Front Oncol 9(), 2019
PMID: 31157165
The tumour glyco-code as a novel immune checkpoint for immunotherapy.
RodrÍguez E, Schetters STT, van Kooyk Y., Nat Rev Immunol 18(3), 2018
PMID: 29398707
RodrÍguez E, Schetters STT, van Kooyk Y., Nat Rev Immunol 18(3), 2018
PMID: 29398707
A One-Step Chemoenzymatic Labeling Strategy for Probing Sialylated Thomsen-Friedenreich Antigen.
Wen L, Liu D, Zheng Y, Huang K, Cao X, Song J, Wang PG., ACS Cent Sci 4(4), 2018
PMID: 29721527
Wen L, Liu D, Zheng Y, Huang K, Cao X, Song J, Wang PG., ACS Cent Sci 4(4), 2018
PMID: 29721527
A Cartography of Siglecs and Sialyltransferases in Gynecologic Malignancies: Is There a Road Towards a Sweet Future?
Haas Q, Simillion C, von Gunten S., Front Oncol 8(), 2018
PMID: 29594046
Haas Q, Simillion C, von Gunten S., Front Oncol 8(), 2018
PMID: 29594046
Triple-negative and HER2-overexpressing breast cancer cell sialylation impacts tumor microenvironment T-lymphocyte subset recruitment: a possible mechanism of tumor escape.
Garbar C, Mascaux C, Merrouche Y, Bensussan A., Cancer Manag Res 10(), 2018
PMID: 29765252
Garbar C, Mascaux C, Merrouche Y, Bensussan A., Cancer Manag Res 10(), 2018
PMID: 29765252
CAR T cell therapy for breast cancer: harnessing the tumor milieu to drive T cell activation.
Bajgain P, Tawinwung S, D'Elia L, Sukumaran S, Watanabe N, Hoyos V, Lulla P, Brenner MK, Leen AM, Vera JF., J Immunother Cancer 6(1), 2018
PMID: 29747685
Bajgain P, Tawinwung S, D'Elia L, Sukumaran S, Watanabe N, Hoyos V, Lulla P, Brenner MK, Leen AM, Vera JF., J Immunother Cancer 6(1), 2018
PMID: 29747685
The Glycoscience of Immunity.
Zhou JY, Oswald DM, Oliva KD, Kreisman LSC, Cobb BA., Trends Immunol 39(7), 2018
PMID: 29759949
Zhou JY, Oswald DM, Oliva KD, Kreisman LSC, Cobb BA., Trends Immunol 39(7), 2018
PMID: 29759949
Latest developments in MUC1 immunotherapy.
Taylor-Papadimitriou J, Burchell JM, Graham R, Beatson R., Biochem Soc Trans 46(3), 2018
PMID: 29784646
Taylor-Papadimitriou J, Burchell JM, Graham R, Beatson R., Biochem Soc Trans 46(3), 2018
PMID: 29784646
Decreased Siglec-9 Expression on Natural Killer Cell Subset Associated With Persistent HBV Replication.
Zhao D, Jiang X, Xu Y, Yang H, Gao D, Li X, Gao L, Ma C, Liang X., Front Immunol 9(), 2018
PMID: 29899741
Zhao D, Jiang X, Xu Y, Yang H, Gao D, Li X, Gao L, Ma C, Liang X., Front Immunol 9(), 2018
PMID: 29899741
O-linked mucin-type glycosylation in breast cancer.
Burchell JM, Beatson R, Graham R, Taylor-Papadimitriou J, Tajadura-Ortega V., Biochem Soc Trans 46(4), 2018
PMID: 29903935
Burchell JM, Beatson R, Graham R, Taylor-Papadimitriou J, Tajadura-Ortega V., Biochem Soc Trans 46(4), 2018
PMID: 29903935
Hypersialylation in Cancer: Modulation of Inflammation and Therapeutic Opportunities.
Rodrigues E, Macauley MS., Cancers (Basel) 10(6), 2018
PMID: 29912148
Rodrigues E, Macauley MS., Cancers (Basel) 10(6), 2018
PMID: 29912148
A Hierarchical Coding Strategy for Live Cell Imaging of Protein-Specific Glycoform.
Li S, Liu Y, Liu L, Feng Y, Ding L, Ju H., Angew Chem Int Ed Engl 57(37), 2018
PMID: 30039903
Li S, Liu Y, Liu L, Feng Y, Ding L, Ju H., Angew Chem Int Ed Engl 57(37), 2018
PMID: 30039903
Targeting sialic acid-Siglec interactions to reverse immune suppression in cancer.
Adams OJ, Stanczak MA, von Gunten S, Läubli H., Glycobiology 28(9), 2018
PMID: 29309569
Adams OJ, Stanczak MA, von Gunten S, Läubli H., Glycobiology 28(9), 2018
PMID: 29309569
Cancer glycan epitopes: biosynthesis, structure and function.
Pearce OMT., Glycobiology 28(9), 2018
PMID: 29546349
Pearce OMT., Glycobiology 28(9), 2018
PMID: 29546349
PD-L1 expression and CD8-positive T cells are associated with favorable survival in HER2-positive invasive breast cancer.
Hou Y, Nitta H, Wei L, Banks PM, Lustberg M, Wesolowski R, Ramaswamy B, Parwani AV, Li Z., Breast J 24(6), 2018
PMID: 30230111
Hou Y, Nitta H, Wei L, Banks PM, Lustberg M, Wesolowski R, Ramaswamy B, Parwani AV, Li Z., Breast J 24(6), 2018
PMID: 30230111
Self-associated molecular patterns mediate cancer immune evasion by engaging Siglecs on T cells.
Stanczak MA, Siddiqui SS, Trefny MP, Thommen DS, Boligan KF, von Gunten S, Tzankov A, Tietze L, Lardinois D, Heinzelmann-Schwarz V, von Bergwelt-Baildon M, Zhang W, Lenz HJ, Han Y, Amos CI, Syedbasha M, Egli A, Stenner F, Speiser DE, Varki A, Zippelius A, Läubli H., J Clin Invest 128(11), 2018
PMID: 30130255
Stanczak MA, Siddiqui SS, Trefny MP, Thommen DS, Boligan KF, von Gunten S, Tzankov A, Tietze L, Lardinois D, Heinzelmann-Schwarz V, von Bergwelt-Baildon M, Zhang W, Lenz HJ, Han Y, Amos CI, Syedbasha M, Egli A, Stenner F, Speiser DE, Varki A, Zippelius A, Läubli H., J Clin Invest 128(11), 2018
PMID: 30130255
Mapping the O-glycoproteome using site-specific extraction of O-linked glycopeptides (EXoO).
Yang W, Ao M, Hu Y, Li QK, Zhang H., Mol Syst Biol 14(11), 2018
PMID: 30459171
Yang W, Ao M, Hu Y, Li QK, Zhang H., Mol Syst Biol 14(11), 2018
PMID: 30459171
Glycans as Key Checkpoints of T Cell Activity and Function.
Pereira MS, Alves I, Vicente M, Campar A, Silva MC, Padrão NA, Pinto V, Fernandes Â, Dias AM, Pinho SS., Front Immunol 9(), 2018
PMID: 30538706
Pereira MS, Alves I, Vicente M, Campar A, Silva MC, Padrão NA, Pinto V, Fernandes Â, Dias AM, Pinho SS., Front Immunol 9(), 2018
PMID: 30538706
Eukaryotic protein glycosylation: a primer for histochemists and cell biologists.
Corfield A., Histochem Cell Biol 147(2), 2017
PMID: 28012131
Corfield A., Histochem Cell Biol 147(2), 2017
PMID: 28012131
Exosomes derived from hypoxic epithelial ovarian cancer deliver microRNA-940 to induce macrophage M2 polarization.
Chen X, Ying X, Wang X, Wu X, Zhu Q, Wang X., Oncol Rep 38(1), 2017
PMID: 28586039
Chen X, Ying X, Wang X, Wu X, Zhu Q, Wang X., Oncol Rep 38(1), 2017
PMID: 28586039
Abnormally glycosylated MUC1 establishes a positive feedback circuit of inflammatory cytokines, mediated by NF-κB p65 and EzH2, in colitis-associated cancer.
Cascio S, Faylo JL, Sciurba JC, Xue J, Ranganathan S, Lohmueller JJ, Beatty PL, Finn OJ., Oncotarget 8(62), 2017
PMID: 29285251
Cascio S, Faylo JL, Sciurba JC, Xue J, Ranganathan S, Lohmueller JJ, Beatty PL, Finn OJ., Oncotarget 8(62), 2017
PMID: 29285251
A bulky glycocalyx fosters metastasis formation by promoting G1 cell cycle progression.
Woods EC, Kai F, Barnes JM, Pedram K, Pickup MW, Hollander MJ, Weaver VM, Bertozzi CR., Elife 6(), 2017
PMID: 29266001
Woods EC, Kai F, Barnes JM, Pedram K, Pickup MW, Hollander MJ, Weaver VM, Bertozzi CR., Elife 6(), 2017
PMID: 29266001
New Chimeric Antigen Receptor Design for Solid Tumors.
Wang Y, Luo F, Yang J, Zhao C, Chu Y., Front Immunol 8(), 2017
PMID: 29312360
Wang Y, Luo F, Yang J, Zhao C, Chu Y., Front Immunol 8(), 2017
PMID: 29312360
83 References
Daten bereitgestellt von Europe PubMed Central.
Microenvironmental regulation of tumor progression and metastasis.
Quail DF, Joyce JA., Nat. Med. 19(11), 2013
PMID: 24202395
Quail DF, Joyce JA., Nat. Med. 19(11), 2013
PMID: 24202395
Immune cell promotion of metastasis.
Kitamura T, Qian BZ, Pollard JW., Nat. Rev. Immunol. 15(2), 2015
PMID: 25614318
Kitamura T, Qian BZ, Pollard JW., Nat. Rev. Immunol. 15(2), 2015
PMID: 25614318
Glycosylation in cancer: mechanisms and clinical implications.
Pinho SS, Reis CA., Nat. Rev. Cancer 15(9), 2015
PMID: 26289314
Pinho SS, Reis CA., Nat. Rev. Cancer 15(9), 2015
PMID: 26289314
O-linked glycosylation in the mammary gland: changes that occur during malignancy.
Burchell JM, Mungul A, Taylor-Papadimitriou J., J Mammary Gland Biol Neoplasia 6(3), 2001
PMID: 11547903
Burchell JM, Mungul A, Taylor-Papadimitriou J., J Mammary Gland Biol Neoplasia 6(3), 2001
PMID: 11547903
Molecular cloning and expression of human tumor-associated polymorphic epithelial mucin.
Gendler SJ, Lancaster CA, Taylor-Papadimitriou J, Duhig T, Peat N, Burchell J, Pemberton L, Lalani EN, Wilson D., J. Biol. Chem. 265(25), 1990
PMID: 1697589
Gendler SJ, Lancaster CA, Taylor-Papadimitriou J, Duhig T, Peat N, Burchell J, Pemberton L, Lalani EN, Wilson D., J. Biol. Chem. 265(25), 1990
PMID: 1697589
An alpha2,3 sialyltransferase (ST3Gal I) is elevated in primary breast carcinomas.
Burchell J, Poulsom R, Hanby A, Whitehouse C, Cooper L, Clausen H, Miles D, Taylor-Papadimitriou J., Glycobiology 9(12), 1999
PMID: 10561455
Burchell J, Poulsom R, Hanby A, Whitehouse C, Cooper L, Clausen H, Miles D, Taylor-Papadimitriou J., Glycobiology 9(12), 1999
PMID: 10561455
Comparison of O-linked carbohydrate chains in MUC-1 mucin from normal breast epithelial cell lines and breast carcinoma cell lines. Demonstration of simpler and fewer glycan chains in tumor cells.
Lloyd KO, Burchell J, Kudryashov V, Yin BW, Taylor-Papadimitriou J., J. Biol. Chem. 271(52), 1996
PMID: 8969192
Lloyd KO, Burchell J, Kudryashov V, Yin BW, Taylor-Papadimitriou J., J. Biol. Chem. 271(52), 1996
PMID: 8969192
The Breast Cancer-Associated Glycoforms of MUC1, MUC1-Tn and sialyl-Tn, Are Expressed in COSMC Wild-Type Cells and Bind the C-Type Lectin MGL.
Beatson R, Maurstad G, Picco G, Arulappu A, Coleman J, Wandell HH, Clausen H, Mandel U, Taylor-Papadimitriou J, Sletmoen M, Burchell JM., PLoS ONE 10(5), 2015
PMID: 25951175
Beatson R, Maurstad G, Picco G, Arulappu A, Coleman J, Wandell HH, Clausen H, Mandel U, Taylor-Papadimitriou J, Sletmoen M, Burchell JM., PLoS ONE 10(5), 2015
PMID: 25951175
Sialylated core 1 based O-linked glycans enhance the growth rate of mammary carcinoma cells in MUC1 transgenic mice.
Mungul A, Cooper L, Brockhausen I, Ryder K, Mandel U, Clausen H, Rughetti A, Miles DW, Taylor-Papadimitriou J, Burchell JM., Int. J. Oncol. 25(4), 2004
PMID: 15375543
Mungul A, Cooper L, Brockhausen I, Ryder K, Mandel U, Clausen H, Rughetti A, Miles DW, Taylor-Papadimitriou J, Burchell JM., Int. J. Oncol. 25(4), 2004
PMID: 15375543
Over-expression of ST3Gal-I promotes mammary tumorigenesis.
Picco G, Julien S, Brockhausen I, Beatson R, Antonopoulos A, Haslam S, Mandel U, Dell A, Pinder S, Taylor-Papadimitriou J, Burchell J., Glycobiology 20(10), 2010
PMID: 20534593
Picco G, Julien S, Brockhausen I, Beatson R, Antonopoulos A, Haslam S, Mandel U, Dell A, Pinder S, Taylor-Papadimitriou J, Burchell J., Glycobiology 20(10), 2010
PMID: 20534593
Siglec-mediated regulation of immune cell function in disease.
Macauley MS, Crocker PR, Paulson JC., Nat. Rev. Immunol. 14(10), 2014
PMID: 25234143
Macauley MS, Crocker PR, Paulson JC., Nat. Rev. Immunol. 14(10), 2014
PMID: 25234143
The membrane-proximal immunoreceptor tyrosine-based inhibitory motif is critical for the inhibitory signaling mediated by Siglecs-7 and -9, CD33-related Siglecs expressed on human monocytes and NK cells.
Avril T, Floyd H, Lopez F, Vivier E, Crocker PR., J. Immunol. 173(11), 2004
PMID: 15557178
Avril T, Floyd H, Lopez F, Vivier E, Crocker PR., J. Immunol. 173(11), 2004
PMID: 15557178
Siglecs and their roles in the immune system.
Crocker PR, Paulson JC, Varki A., Nat. Rev. Immunol. 7(4), 2007
PMID: 17380156
Crocker PR, Paulson JC, Varki A., Nat. Rev. Immunol. 7(4), 2007
PMID: 17380156
Interactions between Siglec-7/9 receptors and ligands influence NK cell-dependent tumor immunosurveillance.
Jandus C, Boligan KF, Chijioke O, Liu H, Dahlhaus M, Demoulins T, Schneider C, Wehrli M, Hunger RE, Baerlocher GM, Simon HU, Romero P, Munz C, von Gunten S., J. Clin. Invest. 124(4), 2014
PMID: 24569453
Jandus C, Boligan KF, Chijioke O, Liu H, Dahlhaus M, Demoulins T, Schneider C, Wehrli M, Hunger RE, Baerlocher GM, Simon HU, Romero P, Munz C, von Gunten S., J. Clin. Invest. 124(4), 2014
PMID: 24569453
Engagement of myelomonocytic Siglecs by tumor-associated ligands modulates the innate immune response to cancer.
Laubli H, Pearce OM, Schwarz F, Siddiqui SS, Deng L, Stanczak MA, Deng L, Verhagen A, Secrest P, Lusk C, Schwartz AG, Varki NM, Bui JD, Varki A., Proc. Natl. Acad. Sci. U.S.A. 111(39), 2014
PMID: 25225409
Laubli H, Pearce OM, Schwarz F, Siddiqui SS, Deng L, Stanczak MA, Deng L, Verhagen A, Secrest P, Lusk C, Schwartz AG, Varki NM, Bui JD, Varki A., Proc. Natl. Acad. Sci. U.S.A. 111(39), 2014
PMID: 25225409
Glycocalyx engineering reveals a Siglec-based mechanism for NK cell immunoevasion.
Hudak JE, Canham SM, Bertozzi CR., Nat. Chem. Biol. 10(1), 2013
PMID: 24292068
Hudak JE, Canham SM, Bertozzi CR., Nat. Chem. Biol. 10(1), 2013
PMID: 24292068
Binding of the sialic acid-binding lectin, Siglec-9, to the membrane mucin, MUC1, induces recruitment of β-catenin and subsequent cell growth.
Tanida S, Akita K, Ishida A, Mori Y, Toda M, Inoue M, Ohta M, Yashiro M, Sawada T, Hirakawa K, Nakada H., J. Biol. Chem. 288(44), 2013
PMID: 24045940
Tanida S, Akita K, Ishida A, Mori Y, Toda M, Inoue M, Ohta M, Yashiro M, Sawada T, Hirakawa K, Nakada H., J. Biol. Chem. 288(44), 2013
PMID: 24045940
Recombinant MUC1 mucin with a breast cancer-like O-glycosylation produced in large amounts in Chinese-hamster ovary cells.
Backstrom M, Link T, Olson FJ, Karlsson H, Graham R, Picco G, Burchell J, Taylor-Papadimitriou J, Noll T, Hansson GC., Biochem. J. 376(Pt 3), 2003
PMID: 12950230
Backstrom M, Link T, Olson FJ, Karlsson H, Graham R, Picco G, Burchell J, Taylor-Papadimitriou J, Noll T, Hansson GC., Biochem. J. 376(Pt 3), 2003
PMID: 12950230
Siglec-9, a novel sialic acid binding member of the immunoglobulin superfamily expressed broadly on human blood leukocytes.
Zhang JQ, Nicoll G, Jones C, Crocker PR., J. Biol. Chem. 275(29), 2000
PMID: 10801862
Zhang JQ, Nicoll G, Jones C, Crocker PR., J. Biol. Chem. 275(29), 2000
PMID: 10801862
The relative activities of the C2GnT1 and ST3Gal-I glycosyltransferases determine O-glycan structure and expression of a tumor-associated epitope on MUC1.
Dalziel M, Whitehouse C, McFarlane I, Brockhausen I, Gschmeissner S, Schwientek T, Clausen H, Burchell JM, Taylor-Papadimitriou J., J. Biol. Chem. 276(14), 2000
PMID: 11118434
Dalziel M, Whitehouse C, McFarlane I, Brockhausen I, Gschmeissner S, Schwientek T, Clausen H, Burchell JM, Taylor-Papadimitriou J., J. Biol. Chem. 276(14), 2000
PMID: 11118434
Molecular mimicry of host sialylated glycans allows a bacterial pathogen to engage neutrophil Siglec-9 and dampen the innate immune response.
Carlin AF, Uchiyama S, Chang YC, Lewis AL, Nizet V, Varki A., Blood 113(14), 2009
PMID: 19196661
Carlin AF, Uchiyama S, Chang YC, Lewis AL, Nizet V, Varki A., Blood 113(14), 2009
PMID: 19196661
CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis.
Qian BZ, Li J, Zhang H, Kitamura T, Zhang J, Campion LR, Kaiser EA, Snyder LA, Pollard JW., Nature 475(7355), 2011
PMID: 21654748
Qian BZ, Li J, Zhang H, Kitamura T, Zhang J, Campion LR, Kaiser EA, Snyder LA, Pollard JW., Nature 475(7355), 2011
PMID: 21654748
Plasminogen activator inhibitor-1 regulates infiltration of macrophages into melanoma via phosphorylation of FAK-Tyr⁹²⁵.
Thapa B, Koo BH, Kim YH, Kwon HJ, Kim DS., Biochem. Biophys. Res. Commun. 450(4), 2014
PMID: 25063025
Thapa B, Koo BH, Kim YH, Kwon HJ, Kim DS., Biochem. Biophys. Res. Commun. 450(4), 2014
PMID: 25063025
Plasminogen activator inhibitor-1 regulates tumor growth and angiogenesis.
McMahon GA, Petitclerc E, Stefansson S, Smith E, Wong MK, Westrick RJ, Ginsburg D, Brooks PC, Lawrence DA., J. Biol. Chem. 276(36), 2001
PMID: 11441025
McMahon GA, Petitclerc E, Stefansson S, Smith E, Wong MK, Westrick RJ, Ginsburg D, Brooks PC, Lawrence DA., J. Biol. Chem. 276(36), 2001
PMID: 11441025
Nuclear factor κB-dependent regulation of angiogenesis, and metastasis in an in vivo model of thyroid cancer is associated with secreted interleukin-8.
Bauerle KT, Schweppe RE, Lund G, Kotnis G, Deep G, Agarwal R, Pozdeyev N, Wood WM, Haugen BR., J. Clin. Endocrinol. Metab. 99(8), 2014
PMID: 24758177
Bauerle KT, Schweppe RE, Lund G, Kotnis G, Deep G, Agarwal R, Pozdeyev N, Wood WM, Haugen BR., J. Clin. Endocrinol. Metab. 99(8), 2014
PMID: 24758177
Silencing of plasminogen activator inhibitor-1 suppresses colorectal cancer progression and liver metastasis.
Chen H, Peng H, Liu W, Sun Y, Su N, Tang W, Zhang X, Wang J, Cui L, Hu P, Liu S., Surgery 158(6), 2015
PMID: 26275833
Chen H, Peng H, Liu W, Sun Y, Su N, Tang W, Zhang X, Wang J, Cui L, Hu P, Liu S., Surgery 158(6), 2015
PMID: 26275833
Environmental immune disruptors, inflammation and cancer risk.
Thompson PA, Khatami M, Baglole CJ, Sun J, Harris SA, Moon EY, Al-Mulla F, Al-Temaimi R, Brown DG, Colacci A, Mondello C, Raju J, Ryan EP, Woodrick J, Scovassi AI, Singh N, Vaccari M, Roy R, Forte S, Memeo L, Salem HK, Amedei A, Hamid RA, Lowe L, Guarnieri T, Bisson WH., Carcinogenesis 36 Suppl 1(), 2015
PMID: 26106141
Thompson PA, Khatami M, Baglole CJ, Sun J, Harris SA, Moon EY, Al-Mulla F, Al-Temaimi R, Brown DG, Colacci A, Mondello C, Raju J, Ryan EP, Woodrick J, Scovassi AI, Singh N, Vaccari M, Roy R, Forte S, Memeo L, Salem HK, Amedei A, Hamid RA, Lowe L, Guarnieri T, Bisson WH., Carcinogenesis 36 Suppl 1(), 2015
PMID: 26106141
Tumor-mediated inhibition of human dendritic cell differentiation and function is consistently counteracted by combined p38 MAPK and STAT3 inhibition.
Oosterhoff D, Lougheed S, van de Ven R, Lindenberg J, van Cruijsen H, Hiddingh L, Kroon J, van den Eertwegh AJ, Hangalapura B, Scheper RJ, de Gruijl TD., Oncoimmunology 1(5), 2012
PMID: 22934257
Oosterhoff D, Lougheed S, van de Ven R, Lindenberg J, van Cruijsen H, Hiddingh L, Kroon J, van den Eertwegh AJ, Hangalapura B, Scheper RJ, de Gruijl TD., Oncoimmunology 1(5), 2012
PMID: 22934257
Nitric oxide synthase in innate and adaptive immunity: an update.
Bogdan C., Trends Immunol. 36(3), 2015
PMID: 25687683
Bogdan C., Trends Immunol. 36(3), 2015
PMID: 25687683
Macrophage activation and polarization: nomenclature and experimental guidelines.
Murray PJ, Allen JE, Biswas SK, Fisher EA, Gilroy DW, Goerdt S, Gordon S, Hamilton JA, Ivashkiv LB, Lawrence T, Locati M, Mantovani A, Martinez FO, Mege JL, Mosser DM, Natoli G, Saeij JP, Schultze JL, Shirey KA, Sica A, Suttles J, Udalova I, van Ginderachter JA, Vogel SN, Wynn TA., Immunity 41(1), 2014
PMID: 25035950
Murray PJ, Allen JE, Biswas SK, Fisher EA, Gilroy DW, Goerdt S, Gordon S, Hamilton JA, Ivashkiv LB, Lawrence T, Locati M, Mantovani A, Martinez FO, Mege JL, Mosser DM, Natoli G, Saeij JP, Schultze JL, Shirey KA, Sica A, Suttles J, Udalova I, van Ginderachter JA, Vogel SN, Wynn TA., Immunity 41(1), 2014
PMID: 25035950
Recombinant tumor-associated MUC1 glycoprotein impairs the differentiation and function of dendritic cells.
Rughetti A, Pellicciotta I, Biffoni M, Backstrom M, Link T, Bennet EP, Clausen H, Noll T, Hansson GC, Burchell JM, Frati L, Taylor-Papadimitriou J, Nuti M., J. Immunol. 174(12), 2005
PMID: 15944279
Rughetti A, Pellicciotta I, Biffoni M, Backstrom M, Link T, Bennet EP, Clausen H, Noll T, Hansson GC, Burchell JM, Frati L, Taylor-Papadimitriou J, Nuti M., J. Immunol. 174(12), 2005
PMID: 15944279
Immunology in the clinic review series; focus on cancer: tumour-associated macrophages; undisputed stars of the inflammatory tumour micrenvironment
Allavena P, Mantovani A., 2012
Allavena P, Mantovani A., 2012
Differential immunosuppressive effect of indoleamine 2,3-dioxygenase (IDO) on primary human CD4+ and CD8+ T cells.
Forouzandeh F, Jalili RB, Germain M, Duronio V, Ghahary A., Mol. Cell. Biochem. 309(1-2), 2007
PMID: 18008147
Forouzandeh F, Jalili RB, Germain M, Duronio V, Ghahary A., Mol. Cell. Biochem. 309(1-2), 2007
PMID: 18008147
Recent insights into the role of the PD-1/PD-L1 pathway in immunological tolerance and autoimmunity.
Gianchecchi E, Delfino DV, Fierabracci A., Autoimmun Rev 12(11), 2013
PMID: 23792703
Gianchecchi E, Delfino DV, Fierabracci A., Autoimmun Rev 12(11), 2013
PMID: 23792703
Human breast cancer cells educate macrophages toward the M2 activation status.
Sousa S, Brion R, Lintunen M, Kronqvist P, Sandholm J, Monkkonen J, Kellokumpu-Lehtinen PL, Lauttia S, Tynninen O, Joensuu H, Heymann D, Maatta JA., Breast Cancer Res. 17(), 2015
PMID: 26243145
Sousa S, Brion R, Lintunen M, Kronqvist P, Sandholm J, Monkkonen J, Kellokumpu-Lehtinen PL, Lauttia S, Tynninen O, Joensuu H, Heymann D, Maatta JA., Breast Cancer Res. 17(), 2015
PMID: 26243145
Macrophage diversity enhances tumor progression and metastasis.
Qian BZ, Pollard JW., Cell 141(1), 2010
PMID: 20371344
Qian BZ, Pollard JW., Cell 141(1), 2010
PMID: 20371344
Myeloid specific human CD33 is an inhibitory receptor with differential ITIM function in recruiting the phosphatases SHP-1 and SHP-2.
Paul SP, Taylor LS, Stansbury EK, McVicar DW., Blood 96(2), 2000
PMID: 10887109
Paul SP, Taylor LS, Stansbury EK, McVicar DW., Blood 96(2), 2000
PMID: 10887109
The functional contribution of calcium ion flux heterogeneity in T cells
Christo SN, Diener KR, Hayball JD., 2015
Christo SN, Diener KR, Hayball JD., 2015
A synthetic inhibitor of the mitogen-activated protein kinase cascade.
Dudley DT, Pang L, Decker SJ, Bridges AJ, Saltiel AR., Proc. Natl. Acad. Sci. U.S.A. 92(17), 1995
PMID: 7644477
Dudley DT, Pang L, Decker SJ, Bridges AJ, Saltiel AR., Proc. Natl. Acad. Sci. U.S.A. 92(17), 1995
PMID: 7644477
Tumor-associated macrophages are correlated with tamoxifen resistance in the postmenopausal breast cancer patients.
Xuan QJ, Wang JX, Nanding A, Wang ZP, Liu H, Lian X, Zhang QY., Pathol. Oncol. Res. 20(3), 2014
PMID: 24414992
Xuan QJ, Wang JX, Nanding A, Wang ZP, Liu H, Lian X, Zhang QY., Pathol. Oncol. Res. 20(3), 2014
PMID: 24414992
Tumor-associated macrophages: from mechanisms to therapy.
Noy R, Pollard JW., Immunity 41(1), 2014
PMID: 25035953
Noy R, Pollard JW., Immunity 41(1), 2014
PMID: 25035953
Pembrolizumab for the treatment of non-small-cell lung cancer.
Garon EB, Rizvi NA, Hui R, Leighl N, Balmanoukian AS, Eder JP, Patnaik A, Aggarwal C, Gubens M, Horn L, Carcereny E, Ahn MJ, Felip E, Lee JS, Hellmann MD, Hamid O, Goldman JW, Soria JC, Dolled-Filhart M, Rutledge RZ, Zhang J, Lunceford JK, Rangwala R, Lubiniecki GM, Roach C, Emancipator K, Gandhi L; KEYNOTE-001 Investigators, Hui R, Chu Q, Leighl N, Chomy F, Dansin E, Lena H, Quere G, Soria JC, Cappuzzo F, Garassino M, Melotti B, Morabito A, Santini D, Brunsvig P, Flotten O, Ahn MJ, Lee DH, Lee JS, Carcereny E, Felip E, Insa A, Yang JC, Tsai CM, Arkenau HT, Grummet S, Middleton G, Aggarwal C, Balmanoukian AS, Bessudo A, Blumenschein GR Jr, Dronca R, Eder JP, Garon EB, Gandhi L, Goldman J, Gubens M, Hager S, Hamid O, Hellmann MD, Horn L, Johnson E, O'Day S, Patnaik A, Ramalingam S, Rizvi NA, Ross H, Socinski M., N. Engl. J. Med. 372(21), 2015
PMID: 25891174
Garon EB, Rizvi NA, Hui R, Leighl N, Balmanoukian AS, Eder JP, Patnaik A, Aggarwal C, Gubens M, Horn L, Carcereny E, Ahn MJ, Felip E, Lee JS, Hellmann MD, Hamid O, Goldman JW, Soria JC, Dolled-Filhart M, Rutledge RZ, Zhang J, Lunceford JK, Rangwala R, Lubiniecki GM, Roach C, Emancipator K, Gandhi L; KEYNOTE-001 Investigators, Hui R, Chu Q, Leighl N, Chomy F, Dansin E, Lena H, Quere G, Soria JC, Cappuzzo F, Garassino M, Melotti B, Morabito A, Santini D, Brunsvig P, Flotten O, Ahn MJ, Lee DH, Lee JS, Carcereny E, Felip E, Insa A, Yang JC, Tsai CM, Arkenau HT, Grummet S, Middleton G, Aggarwal C, Balmanoukian AS, Bessudo A, Blumenschein GR Jr, Dronca R, Eder JP, Garon EB, Gandhi L, Goldman J, Gubens M, Hager S, Hamid O, Hellmann MD, Horn L, Johnson E, O'Day S, Patnaik A, Ramalingam S, Rizvi NA, Ross H, Socinski M., N. Engl. J. Med. 372(21), 2015
PMID: 25891174
MYC regulates the antitumor immune response through CD47 and PD-L1.
Casey SC, Tong L, Li Y, Do R, Walz S, Fitzgerald KN, Gouw AM, Baylot V, Gutgemann I, Eilers M, Felsher DW., Science 352(6282), 2016
PMID: 26966191
Casey SC, Tong L, Li Y, Do R, Walz S, Fitzgerald KN, Gouw AM, Baylot V, Gutgemann I, Eilers M, Felsher DW., Science 352(6282), 2016
PMID: 26966191
The blockade of immune checkpoints in cancer immunotherapy.
Pardoll DM., Nat. Rev. Cancer 12(4), 2012
PMID: 22437870
Pardoll DM., Nat. Rev. Cancer 12(4), 2012
PMID: 22437870
Identification of Siglec-9 as the receptor for MUC16 on human NK cells, B cells, and monocytes.
Belisle JA, Horibata S, Jennifer GA, Petrie S, Kapur A, Andre S, Gabius HJ, Rancourt C, Connor J, Paulson JC, Patankar MS., Mol. Cancer 9(), 2010
PMID: 20497550
Belisle JA, Horibata S, Jennifer GA, Petrie S, Kapur A, Andre S, Gabius HJ, Rancourt C, Connor J, Paulson JC, Patankar MS., Mol. Cancer 9(), 2010
PMID: 20497550
Immunomodulation of monocyte-derived dendritic cells through ligation of tumor-produced mucins to Siglec-9.
Ohta M, Ishida A, Toda M, Akita K, Inoue M, Yamashita K, Watanabe M, Murata T, Usui T, Nakada H., Biochem. Biophys. Res. Commun. 402(4), 2010
PMID: 20971061
Ohta M, Ishida A, Toda M, Akita K, Inoue M, Yamashita K, Watanabe M, Murata T, Usui T, Nakada H., Biochem. Biophys. Res. Commun. 402(4), 2010
PMID: 20971061
Responses of human T cells to peptides flanking the tandem repeat and overlapping the signal sequence of MUC1.
Correa I, Plunkett T, Coleman J, Galani E, Windmill E, Burchell JM, Taylor-Papdimitriou J., Int. J. Cancer 115(5), 2005
PMID: 15729696
Correa I, Plunkett T, Coleman J, Galani E, Windmill E, Burchell JM, Taylor-Papdimitriou J., Int. J. Cancer 115(5), 2005
PMID: 15729696
The ST3Gal-I sialyltransferase controls CD8+ T lymphocyte homeostasis by modulating O-glycan biosynthesis.
Priatel JJ, Chui D, Hiraoka N, Simmons CJ, Richardson KB, Page DM, Fukuda M, Varki NM, Marth JD., Immunity 12(3), 2000
PMID: 10755614
Priatel JJ, Chui D, Hiraoka N, Simmons CJ, Richardson KB, Page DM, Fukuda M, Varki NM, Marth JD., Immunity 12(3), 2000
PMID: 10755614
Sialyl-Lewis(x) on P-selectin glycoprotein ligand-1 is regulated during differentiation and maturation of dendritic cells: a mechanism involving the glycosyltransferases C2GnT1 and ST3Gal I.
Julien S, Grimshaw MJ, Sutton-Smith M, Coleman J, Morris HR, Dell A, Taylor-Papadimitriou J, Burchell JM., J. Immunol. 179(9), 2007
PMID: 17947642
Julien S, Grimshaw MJ, Sutton-Smith M, Coleman J, Morris HR, Dell A, Taylor-Papadimitriou J, Burchell JM., J. Immunol. 179(9), 2007
PMID: 17947642
Cyclooxygenase-2 enzyme induces the expression of the α-2,3-sialyltransferase-3 (ST3Gal-I) in breast cancer.
Sproviero D, Julien S, Burford B, Taylor-Papadimitriou J, Burchell JM., J. Biol. Chem. 287(53), 2012
PMID: 23275522
Sproviero D, Julien S, Burford B, Taylor-Papadimitriou J, Burchell JM., J. Biol. Chem. 287(53), 2012
PMID: 23275522
Characterization of human sialoadhesin, a sialic acid binding receptor expressed by resident and inflammatory macrophage populations.
Hartnell A, Steel J, Turley H, Jones M, Jackson DG, Crocker PR., Blood 97(1), 2001
PMID: 11133773
Hartnell A, Steel J, Turley H, Jones M, Jackson DG, Crocker PR., Blood 97(1), 2001
PMID: 11133773
Negative regulation of Toll-like receptor-4 signaling through the binding of glycosylphosphatidylinositol-anchored glycoprotein, CD14, with the sialic acid-binding lectin, CD33.
Ishida A, Akita K, Mori Y, Tanida S, Toda M, Inoue M, Nakada H., J. Biol. Chem. 289(36), 2014
PMID: 25059667
Ishida A, Akita K, Mori Y, Tanida S, Toda M, Inoue M, Nakada H., J. Biol. Chem. 289(36), 2014
PMID: 25059667
Engagement of Siglec-7 receptor induces a pro-inflammatory response selectively in monocytes.
Varchetta S, Brunetta E, Roberto A, Mikulak J, Hudspeth KL, Mondelli MU, Mavilio D., PLoS ONE 7(9), 2012
PMID: 23029261
Varchetta S, Brunetta E, Roberto A, Mikulak J, Hudspeth KL, Mondelli MU, Mavilio D., PLoS ONE 7(9), 2012
PMID: 23029261
Molecular mimicry of host sialylated glycans allows a bacterial pathogen to engage neutrophil Siglec-9 and dampen the innate immune response.
Carlin AF, Uchiyama S, Chang YC, Lewis AL, Nizet V, Varki A., Blood 113(14), 2009
PMID: 19196661
Carlin AF, Uchiyama S, Chang YC, Lewis AL, Nizet V, Varki A., Blood 113(14), 2009
PMID: 19196661
Luminal lipid regulates CD36 levels and downstream signaling to stimulate chylomicron synthesis.
Tran TT, Poirier H, Clement L, Nassir F, Pelsers MM, Petit V, Degrace P, Monnot MC, Glatz JF, Abumrad NA, Besnard P, Niot I., J. Biol. Chem. 286(28), 2011
PMID: 21610069
Tran TT, Poirier H, Clement L, Nassir F, Pelsers MM, Petit V, Degrace P, Monnot MC, Glatz JF, Abumrad NA, Besnard P, Niot I., J. Biol. Chem. 286(28), 2011
PMID: 21610069
Altered microenvironment promotes progression of preinvasive breast cancer: myoepithelial expression of αvβ6 integrin in DCIS identifies high-risk patients and predicts recurrence.
Allen MD, Thomas GJ, Clark S, Dawoud MM, Vallath S, Payne SJ, Gomm JJ, Dreger SA, Dickinson S, Edwards DR, Pennington CJ, Sestak I, Cuzick J, Marshall JF, Hart IR, Jones JL., Clin. Cancer Res. 20(2), 2013
PMID: 24150233
Allen MD, Thomas GJ, Clark S, Dawoud MM, Vallath S, Payne SJ, Gomm JJ, Dreger SA, Dickinson S, Edwards DR, Pennington CJ, Sestak I, Cuzick J, Marshall JF, Hart IR, Jones JL., Clin. Cancer Res. 20(2), 2013
PMID: 24150233
Normal B lymphocyte development but impaired T cell maturation in CD45-exon6 protein tyrosine phosphatase-deficient mice.
Kishihara K, Penninger J, Wallace VA, Kundig TM, Kawai K, Wakeham A, Timms E, Pfeffer K, Ohashi PS, Thomas ML., Cell 74(1), 1993
PMID: 8334701
Kishihara K, Penninger J, Wallace VA, Kundig TM, Kawai K, Wakeham A, Timms E, Pfeffer K, Ohashi PS, Thomas ML., Cell 74(1), 1993
PMID: 8334701
Tocilizumab inhibits signal transduction mediated by both mIL-6R and sIL-6R, but not by the receptors of other members of IL-6 cytokine family.
Mihara M, Kasutani K, Okazaki M, Nakamura A, Kawai S, Sugimoto M, Matsumoto Y, Ohsugi Y., Int. Immunopharmacol. 5(12), 2005
PMID: 16102523
Mihara M, Kasutani K, Okazaki M, Nakamura A, Kawai S, Sugimoto M, Matsumoto Y, Ohsugi Y., Int. Immunopharmacol. 5(12), 2005
PMID: 16102523
Safety and tumor responses with lambrolizumab (anti-PD-1) in melanoma.
Hamid O, Robert C, Daud A, Hodi FS, Hwu WJ, Kefford R, Wolchok JD, Hersey P, Joseph RW, Weber JS, Dronca R, Gangadhar TC, Patnaik A, Zarour H, Joshua AM, Gergich K, Elassaiss-Schaap J, Algazi A, Mateus C, Boasberg P, Tumeh PC, Chmielowski B, Ebbinghaus SW, Li XN, Kang SP, Ribas A., N. Engl. J. Med. 369(2), 2013
PMID: 23724846
Hamid O, Robert C, Daud A, Hodi FS, Hwu WJ, Kefford R, Wolchok JD, Hersey P, Joseph RW, Weber JS, Dronca R, Gangadhar TC, Patnaik A, Zarour H, Joshua AM, Gergich K, Elassaiss-Schaap J, Algazi A, Mateus C, Boasberg P, Tumeh PC, Chmielowski B, Ebbinghaus SW, Li XN, Kang SP, Ribas A., N. Engl. J. Med. 369(2), 2013
PMID: 23724846
Stearoyl-CoA desaturase 1 and paracrine diffusible signals have a major role in the promotion of breast cancer cell migration induced by cancer-associated fibroblasts.
Angelucci C, Maulucci G, Colabianchi A, Iacopino F, D'Alessio A, Maiorana A, Palmieri V, Papi M, De Spirito M, Di Leone A, Masetti R, Sica G., Br. J. Cancer 112(10), 2015
PMID: 25880005
Angelucci C, Maulucci G, Colabianchi A, Iacopino F, D'Alessio A, Maiorana A, Palmieri V, Papi M, De Spirito M, Di Leone A, Masetti R, Sica G., Br. J. Cancer 112(10), 2015
PMID: 25880005
Crucial role of IL1beta and C3a in the in vitro-response of multipotent mesenchymal stromal cells to inflammatory mediators of polytrauma.
Hengartner NE, Fiedler J, Schrezenmeier H, Huber-Lang M, Brenner RE., PLoS ONE 10(1), 2015
PMID: 25562599
Hengartner NE, Fiedler J, Schrezenmeier H, Huber-Lang M, Brenner RE., PLoS ONE 10(1), 2015
PMID: 25562599
Bortezomib inhibits expression of TGF-β1, IL-10, and CXCR4, resulting in decreased survival and migration of cutaneous T cell lymphoma cells.
Chang TP, Poltoratsky V, Vancurova I., J. Immunol. 194(6), 2015
PMID: 25681335
Chang TP, Poltoratsky V, Vancurova I., J. Immunol. 194(6), 2015
PMID: 25681335
NKP30-B7-H6 Interaction Aggravates Hepatocyte Damage through Up-Regulation of Interleukin-32 Expression in Hepatitis B Virus-Related Acute-On-Chronic Liver Failure.
Zou Y, Bao J, Pan X, Lu Y, Liao S, Wang X, Wang G, Lin D., PLoS ONE 10(8), 2015
PMID: 26241657
Zou Y, Bao J, Pan X, Lu Y, Liao S, Wang X, Wang G, Lin D., PLoS ONE 10(8), 2015
PMID: 26241657
CD33 detection by immunohistochemistry in paraffin-embedded tissues: a new antibody shows excellent specificity and sensitivity for cells of myelomonocytic lineage.
Hoyer JD, Grogg KL, Hanson CA, Gamez JD, Dogan A., Am. J. Clin. Pathol. 129(2), 2008
PMID: 18208813
Hoyer JD, Grogg KL, Hanson CA, Gamez JD, Dogan A., Am. J. Clin. Pathol. 129(2), 2008
PMID: 18208813
The membrane-proximal immunoreceptor tyrosine-based inhibitory motif is critical for the inhibitory signaling mediated by Siglecs-7 and -9, CD33-related Siglecs expressed on human monocytes and NK cells.
Avril T, Floyd H, Lopez F, Vivier E, Crocker PR., J. Immunol. 173(11), 2004
PMID: 15557178
Avril T, Floyd H, Lopez F, Vivier E, Crocker PR., J. Immunol. 173(11), 2004
PMID: 15557178
Expression profiles of novel cell surface molecules on B-cell subsets and plasma cells as analyzed by flow cytometry.
Llinas L, Lazaro A, de Salort J, Matesanz-Isabel J, Sintes J, Engel P., Immunol. Lett. 134(2), 2010
PMID: 20951740
Llinas L, Lazaro A, de Salort J, Matesanz-Isabel J, Sintes J, Engel P., Immunol. Lett. 134(2), 2010
PMID: 20951740
Human Siglec-10 can bind to vascular adhesion protein-1 and serves as its substrate.
Kivi E, Elima K, Aalto K, Nymalm Y, Auvinen K, Koivunen E, Otto DM, Crocker PR, Salminen TA, Salmi M, Jalkanen S., Blood 114(26), 2009
PMID: 19861682
Kivi E, Elima K, Aalto K, Nymalm Y, Auvinen K, Koivunen E, Otto DM, Crocker PR, Salminen TA, Salmi M, Jalkanen S., Blood 114(26), 2009
PMID: 19861682
CD14(+)HLA-DR(low/-) expression: A novel prognostic factor in chronic lymphocytic leukemia.
Liu J, Zhou Y, Huang Q, Qiu L., Oncol Lett 9(3), 2014
PMID: 25663875
Liu J, Zhou Y, Huang Q, Qiu L., Oncol Lett 9(3), 2014
PMID: 25663875
A human NK and K cell subset shares with cytotoxic T cells expression of the antigen recognized by antibody OKT8.
Perussia B, Fanning V, Trinchieri G., J. Immunol. 131(1), 1983
PMID: 6408172
Perussia B, Fanning V, Trinchieri G., J. Immunol. 131(1), 1983
PMID: 6408172
Common variants in P2RY11 are associated with narcolepsy.
Kornum BR, Kawashima M, Faraco J, Lin L, Rico TJ, Hesselson S, Axtell RC, Kuipers H, Weiner K, Hamacher A, Kassack MU, Han F, Knudsen S, Li J, Dong X, Winkelmann J, Plazzi G, Nevsimalova S, Hong SC, Honda Y, Honda M, Hogl B, Ton TG, Montplaisir J, Bourgin P, Kemlink D, Huang YS, Warby S, Einen M, Eshragh JL, Miyagawa T, Desautels A, Ruppert E, Hesla PE, Poli F, Pizza F, Frauscher B, Jeong JH, Lee SP, Strohl KP, Longstreth WT Jr, Kvale M, Dobrovolna M, Ohayon MM, Nepom GT, Wichmann HE, Rouleau GA, Gieger C, Levinson DF, Gejman PV, Meitinger T, Peppard P, Young T, Jennum P, Steinman L, Tokunaga K, Kwok PY, Risch N, Hallmayer J, Mignot E., Nat. Genet. 43(1), 2010
PMID: 21170044
Kornum BR, Kawashima M, Faraco J, Lin L, Rico TJ, Hesselson S, Axtell RC, Kuipers H, Weiner K, Hamacher A, Kassack MU, Han F, Knudsen S, Li J, Dong X, Winkelmann J, Plazzi G, Nevsimalova S, Hong SC, Honda Y, Honda M, Hogl B, Ton TG, Montplaisir J, Bourgin P, Kemlink D, Huang YS, Warby S, Einen M, Eshragh JL, Miyagawa T, Desautels A, Ruppert E, Hesla PE, Poli F, Pizza F, Frauscher B, Jeong JH, Lee SP, Strohl KP, Longstreth WT Jr, Kvale M, Dobrovolna M, Ohayon MM, Nepom GT, Wichmann HE, Rouleau GA, Gieger C, Levinson DF, Gejman PV, Meitinger T, Peppard P, Young T, Jennum P, Steinman L, Tokunaga K, Kwok PY, Risch N, Hallmayer J, Mignot E., Nat. Genet. 43(1), 2010
PMID: 21170044
Frequencies of Circulating MAIT Cells Are Diminished in Chronic HCV, HIV and HCV/HIV Co-Infection and Do Not Recover during Therapy.
Spaan M, Hullegie SJ, Beudeker BJ, Kreefft K, van Oord GW, Groothuismink ZM, van Tilborg M, Rijnders B, de Knegt RJ, Claassen MA, Boonstra A., PLoS ONE 11(7), 2016
PMID: 27416100
Spaan M, Hullegie SJ, Beudeker BJ, Kreefft K, van Oord GW, Groothuismink ZM, van Tilborg M, Rijnders B, de Knegt RJ, Claassen MA, Boonstra A., PLoS ONE 11(7), 2016
PMID: 27416100
Human autoreactive T cells recognize CD1b and phospholipids.
Van Rhijn I, van Berlo T, Hilmenyuk T, Cheng TY, Wolf BJ, Tatituri RV, Uldrich AP, Napolitani G, Cerundolo V, Altman JD, Willemsen P, Huang S, Rossjohn J, Besra GS, Brenner MB, Godfrey DI, Moody DB., Proc. Natl. Acad. Sci. U.S.A. 113(2), 2015
PMID: 26621732
Van Rhijn I, van Berlo T, Hilmenyuk T, Cheng TY, Wolf BJ, Tatituri RV, Uldrich AP, Napolitani G, Cerundolo V, Altman JD, Willemsen P, Huang S, Rossjohn J, Besra GS, Brenner MB, Godfrey DI, Moody DB., Proc. Natl. Acad. Sci. U.S.A. 113(2), 2015
PMID: 26621732
CD4CD8αα lymphocytes, a novel human regulatory T cell subset induced by colonic bacteria and deficient in patients with inflammatory bowel disease.
Sarrabayrouse G, Bossard C, Chauvin JM, Jarry A, Meurette G, Quevrain E, Bridonneau C, Preisser L, Asehnoune K, Labarriere N, Altare F, Sokol H, Jotereau F., PLoS Biol. 12(4), 2014
PMID: 24714093
Sarrabayrouse G, Bossard C, Chauvin JM, Jarry A, Meurette G, Quevrain E, Bridonneau C, Preisser L, Asehnoune K, Labarriere N, Altare F, Sokol H, Jotereau F., PLoS Biol. 12(4), 2014
PMID: 24714093
Modulation of human immune responses by bovine interleukin-10.
den Hartog G, Savelkoul HF, Schoemaker R, Tijhaar E, Westphal AH, de Ruiter T, van de Weg-Schrijver E, van Neerven RJ., PLoS ONE 6(3), 2011
PMID: 21464967
den Hartog G, Savelkoul HF, Schoemaker R, Tijhaar E, Westphal AH, de Ruiter T, van de Weg-Schrijver E, van Neerven RJ., PLoS ONE 6(3), 2011
PMID: 21464967
T-cell-biased immune responses generated by a mucosally targeted adenovirus-σ1 vaccine.
Weaver EA, Mercier GT, Gottschalk S, Barry MA., Mucosal Immunol 5(3), 2012
PMID: 22377931
Weaver EA, Mercier GT, Gottschalk S, Barry MA., Mucosal Immunol 5(3), 2012
PMID: 22377931
CDDO-Me Redirects Activation of Breast Tumor Associated Macrophages.
Ball MS, Shipman EP, Kim H, Liby KT, Pioli PA., PLoS ONE 11(2), 2016
PMID: 26918785
Ball MS, Shipman EP, Kim H, Liby KT, Pioli PA., PLoS ONE 11(2), 2016
PMID: 26918785
Lysophosphatidic acid enhances survival of human CD34(+) cells in ischemic conditions.
Kostic I, Fidalgo-Carvalho I, Aday S, Vazao H, Carvalheiro T, Graos M, Duarte A, Cardoso C, Goncalves L, Carvalho L, Paiva A, Ferreira L., Sci Rep 5(), 2015
PMID: 26553339
Kostic I, Fidalgo-Carvalho I, Aday S, Vazao H, Carvalheiro T, Graos M, Duarte A, Cardoso C, Goncalves L, Carvalho L, Paiva A, Ferreira L., Sci Rep 5(), 2015
PMID: 26553339
Inflammatory and alternatively activated human macrophages attract vessel-associated stem cells, relying on separate HMGB1- and MMP-9-dependent pathways.
Lolmede K, Campana L, Vezzoli M, Bosurgi L, Tonlorenzi R, Clementi E, Bianchi ME, Cossu G, Manfredi AA, Brunelli S, Rovere-Querini P., J. Leukoc. Biol. 85(5), 2009
PMID: 19197071
Lolmede K, Campana L, Vezzoli M, Bosurgi L, Tonlorenzi R, Clementi E, Bianchi ME, Cossu G, Manfredi AA, Brunelli S, Rovere-Querini P., J. Leukoc. Biol. 85(5), 2009
PMID: 19197071
Assessment of costimulation and coinhibition in a triple parameter T cell reporter line: Simultaneous measurement of NF-κB, NFAT and AP-1.
Jutz S, Leitner J, Schmetterer K, Doel-Perez I, Majdic O, Grabmeier-Pfistershammer K, Paster W, Huppa JB, Steinberger P., J. Immunol. Methods 430(), 2016
PMID: 26780292
Jutz S, Leitner J, Schmetterer K, Doel-Perez I, Majdic O, Grabmeier-Pfistershammer K, Paster W, Huppa JB, Steinberger P., J. Immunol. Methods 430(), 2016
PMID: 26780292
The prognostic value of the monoclonal antibodies HMFG1 and HMFG2 in breast cancer.
Berry N, Jones DB, Smallwood J, Taylor I, Kirkham N, Taylor-Papadimitriou J., Br. J. Cancer 51(2), 1985
PMID: 2578285
Berry N, Jones DB, Smallwood J, Taylor I, Kirkham N, Taylor-Papadimitriou J., Br. J. Cancer 51(2), 1985
PMID: 2578285
CD95 co-stimulation blocks activation of naive T cells by inhibiting T cell receptor signaling.
Strauss G, Lindquist JA, Arhel N, Felder E, Karl S, Haas TL, Fulda S, Walczak H, Kirchhoff F, Debatin KM., J. Exp. Med. 206(6), 2009
PMID: 19487421
Strauss G, Lindquist JA, Arhel N, Felder E, Karl S, Haas TL, Fulda S, Walczak H, Kirchhoff F, Debatin KM., J. Exp. Med. 206(6), 2009
PMID: 19487421
Discoidin domain receptor 1 protein is a novel modulator of megakaryocyte-collagen interactions.
Abbonante V, Gruppi C, Rubel D, Gross O, Moratti R, Balduini A., J. Biol. Chem. 288(23), 2013
PMID: 23530036
Abbonante V, Gruppi C, Rubel D, Gross O, Moratti R, Balduini A., J. Biol. Chem. 288(23), 2013
PMID: 23530036
AUTHOR UNKNOWN, 0
Export
Markieren/ Markierung löschen
Markierte Publikationen
Web of Science
Dieser Datensatz im Web of Science®Quellen
PMID: 27595232
PubMed | Europe PMC
Suchen in