Task-dependent Modification of Leg Motor Neuron Synaptic Input Underlying Changes in Walking Direction and Walking Speed
Rosenbaum P, Schmitz J, Schmidt J, Bueschges A (2015)
Journal of Neurophysiology 144(2): 1090-1101.
Zeitschriftenaufsatz
| Veröffentlicht | Englisch
Download
Es wurden keine Dateien hochgeladen. Nur Publikationsnachweis!
Autor*in
Rosenbaum, Philipp;
Schmitz, JosefUniBi ;
Schmidt, Joachim;
Bueschges, Ansgar
Einrichtung
Abstract / Bemerkung
Animals modify their behavior constantly to perform adequately in their environment. In terrestrial locomotion many forms of adaptation exist. Two tasks are changes of walking direction and walking speed. We investigated these two changes in motor output in the stick insect Cuniculina impigra to see how they are brought about at the level of leg motor neurons. We used a semi-intact preparation in which we can record intracellularly from leg motor neurons during walking. In this single-leg preparation the middle leg of the animal steps in a vertical plane on a treadwheel. Stimulation of either abdomen or head reliably elicits fictive forward or backward motor activity, respectively, in the fixed and otherwise deafferented thorax-coxa joint. With a change of walking direction only thorax-coxa-joint motor neurons protractor and retractor changed their activity. The protractor switched from swing activity during forward to stance activity during backward walking, and the retractor from stance to swing. This phase switch was due to corresponding change of phasic synaptic inputs from inhibitory to excitatory and vice versa at specific phases of the step cycle. In addition to phasic synaptic input a tonic depolarization of the motor neurons was present. Analysis of changes in stepping velocity during stance showed only a significant correlation to flexor motor neuron activity, but not to that of retractor and depressor motor neurons during forward walking. These results show that different tasks in the stick insect walking are generated by altering synaptic inputs to specific leg joint motor neurons only.
Erscheinungsjahr
2015
Zeitschriftentitel
Journal of Neurophysiology
Band
144
Ausgabe
2
Seite(n)
1090-1101
ISSN
0022-3077
Page URI
https://pub.uni-bielefeld.de/record/2757567
Zitieren
Rosenbaum P, Schmitz J, Schmidt J, Bueschges A. Task-dependent Modification of Leg Motor Neuron Synaptic Input Underlying Changes in Walking Direction and Walking Speed. Journal of Neurophysiology. 2015;144(2):1090-1101.
Rosenbaum, P., Schmitz, J., Schmidt, J., & Bueschges, A. (2015). Task-dependent Modification of Leg Motor Neuron Synaptic Input Underlying Changes in Walking Direction and Walking Speed. Journal of Neurophysiology, 144(2), 1090-1101. doi:10.1152/jn.00006.2015
Rosenbaum, Philipp, Schmitz, Josef, Schmidt, Joachim, and Bueschges, Ansgar. 2015. “Task-dependent Modification of Leg Motor Neuron Synaptic Input Underlying Changes in Walking Direction and Walking Speed”. Journal of Neurophysiology 144 (2): 1090-1101.
Rosenbaum, P., Schmitz, J., Schmidt, J., and Bueschges, A. (2015). Task-dependent Modification of Leg Motor Neuron Synaptic Input Underlying Changes in Walking Direction and Walking Speed. Journal of Neurophysiology 144, 1090-1101.
Rosenbaum, P., et al., 2015. Task-dependent Modification of Leg Motor Neuron Synaptic Input Underlying Changes in Walking Direction and Walking Speed. Journal of Neurophysiology, 144(2), p 1090-1101.
P. Rosenbaum, et al., “Task-dependent Modification of Leg Motor Neuron Synaptic Input Underlying Changes in Walking Direction and Walking Speed”, Journal of Neurophysiology, vol. 144, 2015, pp. 1090-1101.
Rosenbaum, P., Schmitz, J., Schmidt, J., Bueschges, A.: Task-dependent Modification of Leg Motor Neuron Synaptic Input Underlying Changes in Walking Direction and Walking Speed. Journal of Neurophysiology. 144, 1090-1101 (2015).
Rosenbaum, Philipp, Schmitz, Josef, Schmidt, Joachim, and Bueschges, Ansgar. “Task-dependent Modification of Leg Motor Neuron Synaptic Input Underlying Changes in Walking Direction and Walking Speed”. Journal of Neurophysiology 144.2 (2015): 1090-1101.
Daten bereitgestellt von European Bioinformatics Institute (EBI)
2 Zitationen in Europe PMC
Daten bereitgestellt von Europe PubMed Central.
Six-legged walking in insects: how CPGs, peripheral feedback, and descending signals generate coordinated and adaptive motor rhythms.
Bidaye SS, Bockemühl T, Büschges A., J Neurophysiol 119(2), 2018
PMID: 29070634
Bidaye SS, Bockemühl T, Büschges A., J Neurophysiol 119(2), 2018
PMID: 29070634
Design process and tools for dynamic neuromechanical models and robot controllers.
Szczecinski NS, Hunt AJ, Quinn RD., Biol Cybern 111(1), 2017
PMID: 28224266
Szczecinski NS, Hunt AJ, Quinn RD., Biol Cybern 111(1), 2017
PMID: 28224266
71 References
Daten bereitgestellt von Europe PubMed Central.
Segment specificity of load signal processing depends on walking direction in the stick insect leg muscle control system.
Akay T, Ludwar BCh, Goritz ML, Schmitz J, Buschges A., J. Neurosci. 27(12), 2007
PMID: 17376989
Akay T, Ludwar BCh, Goritz ML, Schmitz J, Buschges A., J. Neurosci. 27(12), 2007
PMID: 17376989
Signals from load sensors underlie interjoint coordination during stepping movements of the stick insect leg.
Akay T, Haehn S, Schmitz J, Buschges A., J. Neurophysiol. 92(1), 2004
PMID: 14999042
Akay T, Haehn S, Schmitz J, Buschges A., J. Neurophysiol. 92(1), 2004
PMID: 14999042
AUTHOR UNKNOWN, 0
Load signals assist the generation of movement-dependent reflex reversal in the femur-tibia joint of stick insects.
Akay T, Buschges A., J. Neurophysiol. 96(6), 2006
PMID: 16956989
Akay T, Buschges A., J. Neurophysiol. 96(6), 2006
PMID: 16956989
AUTHOR UNKNOWN, 0
AUTHOR UNKNOWN, 0
The femur-tibia control system of stick insects--a model system for the study of the neural basis of joint control.
Bassler U., Brain Res. Brain Res. Rev. 18(2), 1993
PMID: 8339107
Bassler U., Brain Res. Brain Res. Rev. 18(2), 1993
PMID: 8339107
Pattern generation for stick insect walking movements--multisensory control of a locomotor program.
Bassler U, Buschges A., Brain Res. Brain Res. Rev. 27(1), 1998
PMID: 9639677
Bassler U, Buschges A., Brain Res. Brain Res. Rev. 27(1), 1998
PMID: 9639677
Contributions of structure and innervation pattern of the stick insect extensor tibiae muscle to the filter characteristics of the muscle-joint system
BÄSsler U, Stein W., J. Exp. Biol. 199(Pt 10), 1996
PMID: 9320094
BÄSsler U, Stein W., J. Exp. Biol. 199(Pt 10), 1996
PMID: 9320094
AUTHOR UNKNOWN, 0
Single perturbations cause sustained changes in searching behavior in stick insects.
Berg E, Buschges A, Schmidt J., J. Exp. Biol. 216(Pt 6), 2012
PMID: 23197090
Berg E, Buschges A, Schmidt J., J. Exp. Biol. 216(Pt 6), 2012
PMID: 23197090
Neuronal control of Drosophila walking direction.
Bidaye SS, Machacek C, Wu Y, Dickson BJ., Science 344(6179), 2014
PMID: 24700860
Bidaye SS, Machacek C, Wu Y, Dickson BJ., Science 344(6179), 2014
PMID: 24700860
Interjoint coordination in the stick insect leg-control system: the role of positional signaling.
Bucher D, Akay T, DiCaprio RA, Buschges A., J. Neurophysiol. 89(3), 2003
PMID: 12626610
Bucher D, Akay T, DiCaprio RA, Buschges A., J. Neurophysiol. 89(3), 2003
PMID: 12626610
Adaptive control for backward quadrupedal walking. II. Hindlimb muscle synergies.
Buford JA, Smith JL., J. Neurophysiol. 64(3), 1990
PMID: 2230922
Buford JA, Smith JL., J. Neurophysiol. 64(3), 1990
PMID: 2230922
Adaptive control for backward quadrupedal walking. I. Posture and hindlimb kinematics.
Buford JA, Zernicke RF, Smith JL., J. Neurophysiol. 64(3), 1990
PMID: 2230921
Buford JA, Zernicke RF, Smith JL., J. Neurophysiol. 64(3), 1990
PMID: 2230921
AUTHOR UNKNOWN, 0
Inhibitory synaptic drive patterns motoneuronal activity in rhythmic preparations of isolated thoracic ganglia in the stick insect.
Buschges A., Brain Res. 783(2), 1998
PMID: 9507159
Buschges A., Brain Res. 783(2), 1998
PMID: 9507159
Lessons for circuit function from large insects: towards understanding the neural basis of motor flexibility.
Buschges A., Curr. Opin. Neurobiol. 22(4), 2012
PMID: 22386530
Buschges A., Curr. Opin. Neurobiol. 22(4), 2012
PMID: 22386530
Synaptic drive contributing to rhythmic activation of motoneurons in the deafferented stick insect walking system.
Buschges A, Ludwar BCh, Bucher D, Schmidt J, DiCaprio RA., Eur. J. Neurosci. 19(7), 2004
PMID: 15078559
Buschges A, Ludwar BCh, Bucher D, Schmidt J, DiCaprio RA., Eur. J. Neurosci. 19(7), 2004
PMID: 15078559
Mechanosensory feedback in walking: From joint control to locomotor patterns.
Buschges A, Gruhn M., Advances in insect physiology. 34(), 2008
PMID: IND44011216
Buschges A, Gruhn M., Advances in insect physiology. 34(), 2008
PMID: IND44011216
AUTHOR UNKNOWN, 0
Nonspiking pathways antagonize the resistance reflex in the thoraco-coxal joint of stick insects.
Buschges A, Schmitz J., J. Neurobiol. 22(3), 1991
PMID: 1890415
Buschges A, Schmitz J., J. Neurobiol. 22(3), 1991
PMID: 1890415
The behavioural transition from straight to curve walking: kinetics of leg movement parameters and the initiation of turning.
Durr V, Ebeling W., J. Exp. Biol. 208(Pt 12), 2005
PMID: 15939767
Durr V, Ebeling W., J. Exp. Biol. 208(Pt 12), 2005
PMID: 15939767
AUTHOR UNKNOWN, 0
Control of flexor motoneuron activity during single leg walking of the stick insect on an electronically controlled treadwheel.
Gabriel JP, Scharstein H, Schmidt J, Buschges A., J. Neurobiol. 56(3), 2003
PMID: 12884263
Gabriel JP, Scharstein H, Schmidt J, Buschges A., J. Neurobiol. 56(3), 2003
PMID: 12884263
Control of stepping velocity in a single insect leg during walking.
Gabriel JP, Buschges A., Philos Trans A Math Phys Eng Sci 365(1850), 2007
PMID: 17148059
Gabriel JP, Buschges A., Philos Trans A Math Phys Eng Sci 365(1850), 2007
PMID: 17148059
Motoneurons, DUM cells, and sensory neurons in an insect thoracic ganglion: a tracing study in the stick insect Carausius morosus.
Goldammer J, Buschges A, Schmidt J., J. Comp. Neurol. 520(2), 2012
PMID: 21618233
Goldammer J, Buschges A, Schmidt J., J. Comp. Neurol. 520(2), 2012
PMID: 21618233
Circuits controlling vertebrate locomotion: moving in a new direction.
Goulding M., Nat. Rev. Neurosci. 10(7), 2009
PMID: 19543221
Goulding M., Nat. Rev. Neurosci. 10(7), 2009
PMID: 19543221
AUTHOR UNKNOWN, 0
Graham, J Exp Biol 296(), 1985
AUTHOR UNKNOWN, 0
Neural networks that co-ordinate locomotion and body orientation in lamprey.
Grillner S, Deliagina T, Ekeberg O , el Manira A, Hill RH, Lansner A, Orlovsky GN, Wallen P., Trends Neurosci. 18(6), 1995
PMID: 7571002
Grillner S, Deliagina T, Ekeberg O , el Manira A, Hill RH, Lansner A, Orlovsky GN, Wallen P., Trends Neurosci. 18(6), 1995
PMID: 7571002
The motor infrastructure: from ion channels to neuronal networks.
Grillner S., Nat. Rev. Neurosci. 4(7), 2003
PMID: 12838332
Grillner S., Nat. Rev. Neurosci. 4(7), 2003
PMID: 12838332
On the central generation of locomotion in the low spinal cat.
Grillner S, Zangger P., Exp Brain Res 34(2), 1979
PMID: 421750
Grillner S, Zangger P., Exp Brain Res 34(2), 1979
PMID: 421750
Control of stepping velocity in the stick insect Carausius morosus.
Gruhn M, von Uckermann G, Westmark S, Wosnitza A, Buschges A, Borgmann A., J. Neurophysiol. 102(2), 2009
PMID: 19535483
Gruhn M, von Uckermann G, Westmark S, Wosnitza A, Buschges A, Borgmann A., J. Neurophysiol. 102(2), 2009
PMID: 19535483
Neural activity in the central complex of the cockroach brain is linked to turning behaviors.
Guo P, Ritzmann RE., J. Exp. Biol. 216(Pt 6), 2012
PMID: 23197098
Guo P, Ritzmann RE., J. Exp. Biol. 216(Pt 6), 2012
PMID: 23197098
Characterization of obstacle negotiation behaviors in the cockroach, Blaberus discoidalis.
Harley CM, English BA, Ritzmann RE., J. Exp. Biol. 212(Pt 10), 2009
PMID: 19411540
Harley CM, English BA, Ritzmann RE., J. Exp. Biol. 212(Pt 10), 2009
PMID: 19411540
Haspel, Caenorhabditis elegans. J Neurosci 30(), 2010
AUTHOR UNKNOWN, 0
Role of proprioceptive signals from an insect femur-tibia joint in patterning motoneuronal activity of an adjacent leg joint.
Hess D, Buschges A., J. Neurophysiol. 81(4), 1999
PMID: 10200220
Hess D, Buschges A., J. Neurophysiol. 81(4), 1999
PMID: 10200220
Sensorimotor pathways involved in interjoint reflex action of an insect leg.
Hess D, Buschges A., J. Neurobiol. 33(7), 1997
PMID: 9407012
Hess D, Buschges A., J. Neurobiol. 33(7), 1997
PMID: 9407012
Jander, 1982
AUTHOR UNKNOWN, 0
Locomotor circuits in the mammalian spinal cord.
Kiehn O., Annu. Rev. Neurosci. 29(), 2006
PMID: 16776587
Kiehn O., Annu. Rev. Neurosci. 29(), 2006
PMID: 16776587
Modulation of membrane potential in mesothoracic moto- and interneurons during stick insect front-leg walking.
Ludwar BCh, Westmark S, Buschges A, Schmidt J., J. Neurophysiol. 94(4), 2005
PMID: 16000520
Ludwar BCh, Westmark S, Buschges A, Schmidt J., J. Neurophysiol. 94(4), 2005
PMID: 16000520
Principles of rhythmic motor pattern generation.
Marder E, Calabrese RL., Physiol. Rev. 76(3), 1996
PMID: 8757786
Marder E, Calabrese RL., Physiol. Rev. 76(3), 1996
PMID: 8757786
During fictive locomotion, graded synaptic currents drive bursts of impulses in swimmeret motor neurons.
Mulloney B., J. Neurosci. 23(13), 2003
PMID: 12843300
Mulloney B., J. Neurosci. 23(13), 2003
PMID: 12843300
Common inhibitory motoneurones in insects.
Pearson KG, Bergman SJ., J. Exp. Biol. 50(2), 1969
PMID: 5795092
Pearson KG, Bergman SJ., J. Exp. Biol. 50(2), 1969
PMID: 5795092
Adaptive control for backward quadrupedal walking V. Mutable activation of bifunctional thigh muscles.
Pratt CA, Buford JA, Smith JL., J. Neurophysiol. 75(2), 1996
PMID: 8714656
Pratt CA, Buford JA, Smith JL., J. Neurophysiol. 75(2), 1996
PMID: 8714656
Adaptive motor behavior in insects.
Ritzmann RE, Buschges A., Curr. Opin. Neurobiol. 17(6), 2007
PMID: 18308559
Ritzmann RE, Buschges A., Curr. Opin. Neurobiol. 17(6), 2007
PMID: 18308559
Origin of excitatory drive to a spinal locomotor network.
Roberts A, Li WC, Soffe SR, Wolf E., Brain Res Rev 57(1), 2007
PMID: 17825424
Roberts A, Li WC, Soffe SR, Wolf E., Brain Res Rev 57(1), 2007
PMID: 17825424
Activity patterns and timing of muscle activity in the forward walking and backward walking stick insect Carausius morosus.
Rosenbaum P, Wosnitza A, Buschges A, Gruhn M., J. Neurophysiol. 104(3), 2010
PMID: 20668273
Rosenbaum P, Wosnitza A, Buschges A, Gruhn M., J. Neurophysiol. 104(3), 2010
PMID: 20668273
Role of presynaptic inputs to proprioceptive afferents in tuning sensorimotor pathways of an insect joint control network.
Sauer AE, Buschges A, Stein W., J. Neurobiol. 32(4), 1997
PMID: 9087889
Sauer AE, Buschges A, Stein W., J. Neurobiol. 32(4), 1997
PMID: 9087889
AUTHOR UNKNOWN, 0
AUTHOR UNKNOWN, 0
AUTHOR UNKNOWN, 0
Excitatory and inhibitory postsynaptic potentials in alpha-motoneurons produced during fictive locomotion by stimulation of the mesencephalic locomotor region.
Shefchyk SJ, Jordan LM., J. Neurophysiol. 53(6), 1985
PMID: 4009222
Shefchyk SJ, Jordan LM., J. Neurophysiol. 53(6), 1985
PMID: 4009222
Tonic and phasic synaptic input to spinal cord motoneurons during fictive locomotion in frog embryos.
Soffe SR, Roberts A., J. Neurophysiol. 48(6), 1982
PMID: 6296327
Soffe SR, Roberts A., J. Neurophysiol. 48(6), 1982
PMID: 6296327
The central complex and the genetic dissection of locomotor behaviour.
Strauss R., Curr. Opin. Neurobiol. 12(6), 2002
PMID: 12490252
Strauss R., Curr. Opin. Neurobiol. 12(6), 2002
PMID: 12490252
A higher control center of locomotor behavior in the Drosophila brain.
Strauss R, Heisenberg M., J. Neurosci. 13(5), 1993
PMID: 8478679
Strauss R, Heisenberg M., J. Neurosci. 13(5), 1993
PMID: 8478679
Spatial co-ordination of foot contacts in unrestrained climbing insects.
Theunissen LM, Vikram S, Durr V., J. Exp. Biol. 217(Pt 18), 2014
PMID: 25013102
Theunissen LM, Vikram S, Durr V., J. Exp. Biol. 217(Pt 18), 2014
PMID: 25013102
Von, 2008
Premotor interneurons in the local control of stepping motor output for the stick insect single middle leg.
von Uckermann G, Buschges A., J. Neurophysiol. 102(3), 2009
PMID: 19605613
von Uckermann G, Buschges A., J. Neurophysiol. 102(3), 2009
PMID: 19605613
Origin of phasic synaptic inhibition in myotomal motoneurons during fictive locomotion in the lamprey.
Wallen P, Shupliakov O, Hill RH., Exp Brain Res 96(2), 1993
PMID: 8270016
Wallen P, Shupliakov O, Hill RH., Exp Brain Res 96(2), 1993
PMID: 8270016
AUTHOR UNKNOWN, 0
AUTHOR UNKNOWN, 0
Wolf, J Exp Biol 304(), 1990
Inhibitory motoneurons in arthropod motor control: organisation, function, evolution.
Wolf H., J. Comp. Physiol. A Neuroethol. Sens. Neural. Behav. Physiol. 200(8), 2014
PMID: 24965579
Wolf H., J. Comp. Physiol. A Neuroethol. Sens. Neural. Behav. Physiol. 200(8), 2014
PMID: 24965579
Inter-leg coordination in the control of walking speed in Drosophila.
Wosnitza A, Bockemuhl T, Dubbert M, Scholz H, Buschges A., J. Exp. Biol. 216(Pt 3), 2012
PMID: 23038731
Wosnitza A, Bockemuhl T, Dubbert M, Scholz H, Buschges A., J. Exp. Biol. 216(Pt 3), 2012
PMID: 23038731
Segment-specific and state-dependent targeting accuracy of the stick insect.
Wosnitza A, Engelen J, Gruhn M., J. Exp. Biol. 216(Pt 22), 2013
PMID: 23948479
Wosnitza A, Engelen J, Gruhn M., J. Exp. Biol. 216(Pt 22), 2013
PMID: 23948479
Reticulospinal neurons controlling forward and backward swimming in the lamprey.
Zelenin PV., J. Neurophysiol. 105(3), 2011
PMID: 21248057
Zelenin PV., J. Neurophysiol. 105(3), 2011
PMID: 21248057
Export
Markieren/ Markierung löschen
Markierte Publikationen
Web of Science
Dieser Datensatz im Web of Science®Quellen
PMID: 26063769
PubMed | Europe PMC
Suchen in